Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GAS7	52	5	57	1485.621
#2	SNAI2	46	2	48	487.588
#3	NR3C1	44	2	46	540.057
#4	NFE2L3	44	2	46	235.736
#5	MSX1	41	7	48	1229.885
#6	FOXQ1	38	4	42	46.243
#7	TRIM29	37	8	45	3522.631
#8	SPIB	33	3	36	24.692
#9	NKX2-3	33	7	40	129.946
#10	MAF	31	8	39	1709.399
#11	SLC26A3	31	7	38	773.443
#12	THRB	29	9	38	172.503
#13	TEAD4	29	7	36	132.663
#14	NFATC2	27	9	36	3222.32
#15	HOXD10	27	8	35	2742.943
#16	ASCL2	26	8	34	189.335
#17	GLI2	25	13	38	2097.425
#18	ZNF643	25	11	36	4193.887
#19	MYCN	25	10	35	3383.16
#20	GRHL3	24	13	37	393.003
#21	ARNTL2	24	6	30	1522.689
#22	PITX2	23	9	32	4810.372
#23	HSF1	23	11	34	1196.757
#24	ZNF202	23	12	35	1439.956
#25	NR5A2	23	13	36	1114.294
#26	FOXP2	23	9	32	715.335
#27	FOXK2	22	9	31	3526.397
#28	SOX10	22	10	32	369.912
#29	ZFPM2	22	10	32	1426.333
#30	MSX2	21	14	35	439.351
#31	FEV	20	9	29	242.118
#32	NEUROD1	20	12	32	4012.756
#33	ETV4	20	9	29	1607.733
#34	AHCTF1	20	11	31	1753.195
#35	NKX2-5	20	11	31	1482.53
#36	ISL1	19	8	27	510.925
#37	TCF3	19	10	29	264.816
#38	TCF21	19	6	25	284.397
#39	FOSL1	19	10	29	311.213
#40	FOXO1	19	14	33	1348.672
#41	KLF17	18	10	28	1647.406
#42	SOX18	18	7	25	1628.535
#43	NKX6-2	18	10	28	2525.65
#44	HLF	18	12	30	1197.636
#45	ZNF277	18	7	25	1009.474
#46	EBF1	18	14	32	754.474
#47	ETS1	18	9	27	1381.927
#48	THRA	18	10	28	1488.288
#49	HOXA5	17	7	24	225.395
#50	TWIST2	17	8	25	275.101
#51	HOXB8	17	11	28	926.63
#52	TCF12	17	9	26	1827.215
#53	NKX2-8	17	8	25	1163.614
#54	MEIS1	17	9	26	2084.451
#55	BACH2	17	15	32	1529.738
#56	WNT5A	17	10	27	764.408
#57	ARX	17	12	29	1149.677
#58	TRERF1	16	11	27	863.931
#59	NPAT	16	7	23	1024.348
#60	ZIC1	16	11	27	1298.753
#61	ZIC2	16	15	31	2498.404
#62	CSDA	16	8	24	1401.933
#63	ZRANB2	16	11	27	1802.077
#64	MLLT10	16	13	29	2761.702
#65	TLX3	16	9	25	914.298
#66	ZNF132	16	10	26	498.585
#67	EN1	15	12	27	1700.385
#68	ZSCAN18	15	9	24	955.128
#69	C12orf28	15	8	23	848.005
#70	SIM2	15	13	28	1066.036
#71	MXD1	15	10	25	711.92
#72	SCAND1	15	9	24	813.457
#73	FOS	15	8	23	1157.777
#74	CLOCK	15	11	26	1587.927
#75	HOXA9	15	7	22	348.84
#76	KLF9	15	13	28	2816.257
#77	SOX17	15	11	26	1063.897
#78	ESR2	15	6	21	377.936
#79	PAX4	15	6	21	687.46
#80	HOXD11	15	6	21	1015.233
#81	ZSCAN1	15	10	25	1240.886
#82	ZNF24	15	11	26	1256.221
#83	SOX30	15	10	25	1477.322
#84	MAFK	15	11	26	1471.54
#85	MEF2C	15	9	24	251.508
#86	LHX4	15	10	25	1364.208
#87	GATA6	15	12	27	1600.811
#88	SOX4	15	8	23	919.723
#89	MYBL2	15	9	24	186.733
#90	ELK4	15	10	25	1361.565
#91	SIX1	14	13	27	1427.051
#92	VENTX	14	10	24	1197.253
#93	RAX2	14	13	27	2812.521
#94	FOXD1	14	14	28	1642.747
#95	ZNF83	14	13	27	2052.729
#96	BATF3	14	14	28	1482.353
#97	NOTCH1	14	11	25	1260.11
#98	SCAND3	14	13	27	834.241
#99	NFE2L2	14	10	24	1052.105
#100	ASCL1	14	8	22	3649.424
#101	NR2C1	14	7	21	1079.717
#102	FOXK1	14	10	24	1160.951
#103	ENO1	14	13	27	2261.325
#104	IRX3	14	12	26	402.174
#105	HOXD3	14	13	27	2116.628
#106	ZFP42	14	11	25	1446.539
#107	FOXC2	14	11	25	991.624
#108	MYC	14	10	24	918.801
#109	BHLHE41	14	11	25	1018.83
#110	CBL	14	12	26	2352.838
#111	NKX6-1	14	9	23	1241.275
#112	LMX1A	14	8	22	979.083
#113	LEF1	14	12	26	1562.294
#114	PRRX1	14	14	28	3721.842
#115	MEOX1	14	12	26	1282.042
#116	SPI1	14	13	27	1218.721
#117	REST	14	8	22	1317.657
#118	FUBP1	14	13	27	1463.031
#119	GBX2	14	10	24	1517.499
#120	HES6	14	7	21	604.263
#121	HES5	14	16	30	698.355
#122	MIXL1	14	12	26	1353.693
#123	ZNF3	14	7	21	984.5
#124	NANOGNB	14	10	24	848.431
#125	ZNF207	14	17	31	2293.214
#126	TFAP2C	14	11	25	1237.965
#127	ZNF219	13	12	25	929.145
#128	MYF6	13	17	30	2458.985
#129	BACH1	13	15	28	1440.795
#130	PITX1	13	11	24	506.126
#131	MEF2D	13	6	19	950.011
#132	CREB5	13	13	26	1447.868
#133	MLXIPL	13	15	28	1672.523
#134	LZTS1	13	9	22	974.793
#135	SRY	13	13	26	1138.839
#136	MNT	13	9	22	984.321
#137	TSC22D3	13	17	30	2172.404
#138	HOXB6	13	11	24	829.616
#139	ATF6B	13	14	27	1226.907
#140	SOX8	13	9	22	432.026
#141	ONECUT1	13	10	23	1621.388
#142	EPAS1	13	8	21	877.217
#143	ZNF215	13	13	26	1343.126
#144	ALX4	13	6	19	677.051
#145	ESRRG	13	11	24	847.514
#146	TFAP2E	13	7	20	867.465
#147	MLL	13	12	25	1410.066
#148	MGA	13	12	25	1291.703
#149	MECOM	13	9	22	707.253
#150	SOX1	13	14	27	792.693
#151	VSX1	13	14	27	1669.866
#152	TBX10	13	10	23	835.092
#153	CRX	13	11	24	1264.886
#154	TFAP2A	13	13	26	419.788
#155	SMAD9	13	8	21	393.764
#156	TRPS1	13	10	23	855.996
#157	PEG3	13	8	21	967.34
#158	ARNT	13	14	27	1786.213
#159	RORB	13	14	27	1416.204
#160	GSC2	13	12	25	1449.038
#161	ZNF131	13	8	21	1077.082
#162	ZXDC	13	9	22	1263.113
#163	GATA3	13	11	24	1540.307
#164	SNAPC5	13	13	26	1595.427
#165	RUNX2	13	9	22	1838.925
#166	FOXH1	13	12	25	1494.93
#167	NR2F6	13	10	23	1065.644
#168	TBX3	12	12	24	486.415
#169	OTX2	12	12	24	1210.904
#170	PKNOX1	12	9	21	377.278
#171	POU3F2	12	12	24	1218.877
#172	KLF16	12	13	25	1117.472
#173	TLX2	12	14	26	1308.225
#174	ELK1	12	12	24	1545.65
#175	DMRT2	12	12	24	1492.07
#176	NRL	12	11	23	1020.003
#177	IRX4	12	12	24	1189.823
#178	PLSCR1	12	12	24	1024.141
#179	SOX21	12	9	21	595.24
#180	SMAD6	12	11	23	733.123
#181	FOXE1	12	14	26	1412.769
#182	HDX	12	10	22	1037.555
#183	SREBF1	12	8	20	1376.395
#184	PPARD	12	10	22	1585.842
#185	TFDP3	12	15	27	1512.806
#186	SIX6	12	15	27	1384.227
#187	GLIS2	12	11	23	890.462
#188	HOXD9	12	5	17	232.96
#189	DMBX1	12	11	23	905.569
#190	PHTF1	12	14	26	1287.273
#191	NR1H4	12	8	20	1062.414
#192	CSRNP3	12	11	23	1124.756
#193	PURA	12	12	24	1247.87
#194	NEUROG1	12	11	23	1066.467
#195	RUNX1	12	14	26	1529.01
#196	SP140	12	11	23	2196.19
#197	ZNF157	12	10	22	1143.575
#198	HCFC1	11	12	23	1459.434
#199	DLX6	11	15	26	1068.669
#200	SPIC	11	9	20	734.896
#201	IRX5	11	9	20	646.618
#202	SOX2	11	11	22	928.171
#203	BCL11B	11	14	25	1390.069
#204	ELF5	11	15	26	1887.001
#205	TEF	11	12	23	958.748
#206	TFAP2B	11	13	24	1366.14
#207	NR2E3	11	15	26	1329.922
#208	ZFHX4	11	13	24	1583.121
#209	FOXD3	11	10	21	334.914
#210	POU2F3	11	10	21	1496.525
#211	EN2	11	17	28	2072.98
#212	ETV5	11	10	21	699.582
#213	STRN3	11	14	25	1135.268
#214	ARNT2	11	18	29	1201.742
#215	ZNF396	11	13	24	1266.709
#216	SNAI3	11	10	21	1419.932
#217	PHOX2A	11	13	24	1033.352
#218	ZFP36L1	11	4	15	403.817
#219	SCAND2	11	13	24	1149.947
#220	TFAP2D	11	12	23	1011.25
#221	ERF	11	12	23	1324.32
#222	CDKN2A	11	10	21	1204.701
#223	NR4A1	11	11	22	754.134
#224	HIC1	11	12	23	1088.106
#225	PRDM2	11	10	21	1053.914
#226	PDX1	11	11	22	1678.418
#227	HESX1	11	11	22	2245.568
#228	LMO4	11	9	20	795.325
#229	RARB	11	10	21	925.74
#230	GCM1	11	12	23	1170.2
#231	CEBPE	11	13	24	1394.679
#232	ZNF434	11	7	18	507.159
#233	E2F2	11	7	18	714.629
#234	AFF4	11	9	20	842.704
#235	BCL6	11	15	26	1052.744
#236	ETV6	11	8	19	618.438
#237	TAF4	11	9	20	649.228
#238	SMAD2	11	13	24	1470.528
#239	NPAS2	11	12	23	1121.424
#240	MESP1	11	8	19	5033.357
#241	ZIC5	11	10	21	1472.45
#242	HNF4A	11	13	24	793.796
#243	NR0B1	10	17	27	1578.172
#244	TCF7	10	9	19	327.846
#245	WT1	10	12	22	1245.303
#246	HOXB13	10	9	19	2880.399
#247	RXRG	10	10	20	629.618
#248	SLC2A4RG	10	13	23	1327.367
#249	FOXC1	10	14	24	1175.532
#250	HOXD4	10	12	22	3974.096
#251	IKZF3	10	14	24	1086.229
#252	FOXS1	10	12	22	955.032
#253	HEY2	10	13	23	811.469
#254	NFAT5	10	12	22	835.277
#255	HOPX	10	10	20	1136.883
#256	ESX1	10	14	24	1143.749
#257	TEAD2	10	11	21	561.577
#258	ZNF92	10	10	20	1029.578
#259	RFX3	10	10	20	388.046
#260	NCOR1	10	10	20	1151.863
#261	TBX15	10	17	27	1419.48
#262	LHX9	10	15	25	1203.38
#263	NR4A3	10	12	22	1161.905
#264	GSX1	10	10	20	1299.652
#265	HOXC11	10	12	22	942.863
#266	PAX7	10	14	24	1294.362
#267	POU6F2	10	11	21	958.51
#268	ZBTB17	10	12	22	866.928
#269	HOXA2	10	9	19	801.151
#270	TAF13	10	6	16	526.283
#271	POU4F1	10	13	23	918.056
#272	ZNF167	10	17	27	1286.49
#273	TAF10	10	13	23	1716.566
#274	ZFHX2	10	13	23	946.054
#275	ZHX2	10	13	23	1556.652
#276	ATF7	10	9	19	759.022
#277	PLAG1	10	12	22	1139.926
#278	ZSCAN20	10	12	22	1350.52
#279	MITF	10	12	22	1210.437
#280	ESR1	10	15	25	1439.018
#281	ZNF449	10	10	20	1049.601
#282	CCRN4L	10	6	16	483.428
#283	NFX1	10	12	22	1191.687
#284	SUPT6H	10	12	22	1019.62
#285	LHX3	10	15	25	1657.201
#286	TBX6	10	11	21	609.505
#287	FOXO3	10	14	24	1286.608
#288	C11orf9	10	7	17	774.769
#289	SOX11	10	10	20	896.388
#290	RUNX1T1	10	13	23	492.871
#291	MEOX2	10	16	26	643.996
#292	PBX4	10	12	22	674.184
#293	ONECUT2	10	11	21	691.054
#294	L3MBTL4	10	8	18	720.79
#295	ETV7	10	14	24	893.819
#296	ZNF496	10	11	21	923.28
#297	VDR	10	15	25	957.846
#298	C2orf3	9	12	21	1303.603
#299	SP3	9	9	18	569.07
#300	ZSCAN10	9	11	20	1530.636
#301	VTN	9	12	21	1356.501
#302	IKZF4	9	12	21	1410.371
#303	MYT1	9	8	17	911.662
#304	ZFHX3	9	12	21	810.399
#305	ZIC3	9	13	22	1294.713
#306	ETV3	9	11	20	1086.944
#307	LASS5	9	12	21	837.513
#308	POU3F3	9	8	17	760.871
#309	MYT1L	9	9	18	842.176
#310	NR1I3	9	15	24	1539.329
#311	ZNF639	9	18	27	2003.037
#312	SP4	9	7	16	636.049
#313	CREBBP	9	12	21	1272.63
#314	HOXC9	9	11	20	872.961
#315	SOX7	9	10	19	962.639
#316	ZNF446	9	5	14	257.281
#317	TULP4	9	15	24	989.851
#318	ZNF397	9	10	19	1004.691
#319	POU2F2	9	9	18	858.744
#320	ZNF90	9	12	21	1275.407
#321	ZEB1	9	13	22	1132.547
#322	PHF1	9	10	19	705.385
#323	RFXAP	9	13	22	692.967
#324	NFIB	9	11	20	998.57
#325	RELA	9	11	20	662.611
#326	ONECUT3	9	8	17	1491.997
#327	HOXC8	9	11	20	914.174
#328	CUX2	9	12	21	1039.959
#329	POU4F3	9	12	21	974.2
#330	MYF5	9	14	23	1745.074
#331	PAX6	9	8	17	661.123
#332	EGR1	9	9	18	523.439
#333	HIF3A	9	11	20	838.036
#334	FOXG1	9	11	20	842.573
#335	MESP2	9	10	19	222.767
#336	NOBOX	9	13	22	1379.03
#337	ISL2	9	14	23	1245.712
#338	HAND1	9	10	19	1278.865
#339	TADA2A	9	10	19	591.189
#340	ZNF81	9	11	20	737.976
#341	CREM	9	9	18	994.897
#342	HOXA13	9	4	13	112.502
#343	TBX5	9	15	24	918.921
#344	FOXN3	9	16	25	1202.661
#345	TLX1	9	10	19	778.758
#346	TCF20	9	16	25	1100.077
#347	FOXI1	9	11	20	2275.207
#348	ZSCAN2	9	11	20	999.677
#349	SCRT1	9	16	25	1295.235
#350	ZNF175	9	13	22	761.548
#351	FOXA2	9	12	21	896.019
#352	NFATC1	9	13	22	1211.632
#353	HNF1B	9	16	25	860.834
#354	RARA	8	15	23	771.444
#355	HNRNPAB	8	11	19	827.964
#356	KCNH8	8	12	20	774.127
#357	FLI1	8	13	21	993.631
#358	MMP14	8	12	20	822.012
#359	HOXD13	8	7	15	390.095
#360	HOXD12	8	12	20	963.38
#361	HMG20B	8	11	19	855.636
#362	FOXL2	8	13	21	901.66
#363	TFEC	8	13	21	848.302
#364	EGR4	8	17	25	939.069
#365	TAF1B	8	12	20	718.292
#366	ZNF169	8	11	19	736.805
#367	ZKSCAN3	8	14	22	932.133
#368	SIX3	8	11	19	1233.59
#369	FOSB	8	7	15	454.44
#370	GATA4	8	16	24	1187.291
#371	MYCL1	8	11	19	637.62
#372	ATF5	8	8	16	1060.805
#373	OLIG2	8	9	17	563.079
#374	ZNF117	8	9	17	898.565
#375	HOXA11	8	11	19	443.419
#376	MTA2	8	11	19	887.228
#377	FOXR2	8	11	19	841.25
#378	PURB	8	7	15	483.982
#379	FOXP3	8	15	23	1020.466
#380	HOXA1	8	9	17	332.653
#381	CREBZF	8	12	20	807.076
#382	PAX8	8	11	19	750.506
#383	RORA	8	16	24	839.508
#384	POU5F2	8	12	20	836.11
#385	NR2E1	7	17	24	982.867
#386	RCAN1	7	15	22	847.649
#387	ANKRD30A	7	11	18	546.361
#388	NANOG	7	16	23	1579.818
#389	SOX12	7	14	21	768.969
#390	ERG	7	17	24	815.416
#391	GSX2	7	14	21	734.625
#392	DLX4	7	14	21	1043.988
#393	SOX6	7	16	23	1089.477
#394	PBX3	7	15	22	862.964
#395	ZSCAN4	7	12	19	1548.017
#396	TADA3	7	12	19	1090.052
#397	HOXA3	7	13	20	965.686
#398	TSC22D1	7	12	19	1011.88
#399	KLF12	7	12	19	1842.103
#400	GATAD2A	7	12	19	670.252
#401	SOX13	7	11	18	906.12
#402	BARX1	7	18	25	1174.776
#403	RERE	7	12	19	936.817
#404	SMAD4	7	10	17	730.354
#405	TBX1	7	12	19	676.827
#406	BLZF1	7	12	19	757.75
#407	JUND	7	14	21	758.269
#408	HMGA2	7	10	17	671.961
#409	SIM1	7	15	22	2607.327
#410	RXRB	7	12	19	844.158
#411	GATA1	7	9	16	573.42
#412	POU6F1	7	13	20	538.505
#413	HIRA	7	15	22	646.852
#414	CTBP1	7	12	19	828.317
#415	NFIX	7	15	22	928.933
#416	SIN3A	7	9	16	815.236
#417	ZNF71	7	12	19	779.753
#418	IKZF1	7	15	22	624.743
#419	CREB3L3	7	17	24	1145.697
#420	DMRT1	7	14	21	951.357
#421	ALS2CR8	7	12	19	1025.745
#422	NFYA	7	10	17	513.888
#423	RARG	6	13	19	1047.827
#424	ST18	6	17	23	482.604
#425	DLX3	6	10	16	507.706
#426	ZNF85	6	13	19	915.644
#427	ZNF80	6	12	18	753.905
#428	DLX1	6	15	21	750.197
#429	FOXJ1	6	10	16	544.672
#430	TSC22D2	6	14	20	692.961
#431	ZNF93	6	12	18	522.462
#432	TP73	6	13	19	687.698
#433	ZEB2	6	12	18	454.852
#434	ZNF135	6	15	21	743.581
#435	POU2F1	6	11	17	692.165
#436	PCGF2	6	12	18	764.21
#437	ATF2	6	14	20	628.784
#438	POU4F2	6	11	17	535.233
#439	NFIC	6	9	15	451.455
#440	HNF1A	6	7	13	335.061
#441	MEIS3	6	13	19	594.053
#442	MKX	6	16	22	1117.596
#443	NFIA	6	14	20	725.563
#444	ZNF70	6	11	17	528.718
#445	TBX2	6	10	16	632.051
#446	STAT5B	5	12	17	1140.572
#447	POU3F1	5	12	17	885.215
#448	CITED1	5	10	15	624.414
#449	HMGB2	5	11	16	502.624
#450	HSF5	5	11	16	845.176
#451	ZNF500	5	12	17	457.457
#452	ZNF154	5	9	14	346.345
#453	TAL1	5	12	17	709.508
#454	TBX22	5	18	23	768.306
#455	SIX2	5	10	15	537.285
#456	TSHZ2	5	11	16	561.671
#457	HOXA4	5	7	12	490.473
#458	PGBD1	5	10	15	408.294
#459	GATA5	5	15	20	781.831
#460	DLX2	5	10	15	768.543
#461	FOXL1	5	13	18	660.203
#462	MYNN	5	13	18	598.315
#463	IRF4	5	13	18	643.21
#464	BRD8	5	12	17	525.032
#465	ZSCAN12	5	11	16	849.136
#466	SOX5	5	12	17	550.715
#467	ZNF444	5	7	12	333.458
#468	PKNOX2	5	16	21	1134.465
#469	TBR1	5	17	22	654.262
#470	POU1F1	4	11	15	411.628
#471	PHOX2B	4	12	16	330.996
#472	TBX20	4	16	20	612.27
#473	NEUROD2	4	13	17	541.336
#474	TP63	4	14	18	529.782
#475	ZNF287	4	13	17	415.363
#476	FOXN4	4	8	12	347.509
#477	ETV1	4	10	14	448.66
#478	ZNF483	4	13	17	392.776
#479	HOXD1	4	14	18	541.222
#480	NFKB2	4	22	26	1425.859
#481	NPAS1	4	14	18	378.05
#482	NKX2-1	4	14	18	765.775
#483	HOXC12	4	10	14	311.269
#484	ZSCAN23	4	14	18	835.788
#485	SIX4	4	11	15	495.027
#486	BNC1	4	12	16	389.859
#487	PTH	4	13	17	461.238
#488	LHX2	3	15	18	678.912
#489	KDM5B	3	13	16	538.005
#490	GATAD1	3	15	18	286.839
#491	PGR	3	14	17	330.46
#492	ALX3	3	15	18	827.838
#493	TFE3	2	17	19	211.15
#494	ESRRB	2	18	20	588.276
#495	GLI3	2	12	14	267.04
#496	PAX3	2	15	17	221.757
#497	LHX8	2	17	19	276.711
#498	PPARA	1	12	13	74.892
#499	IRX2	1	17	18	107.876
#500	NFE2	1	12	13	116.417