Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	BCL11B	60	5	65	9586.139
#2	GRHL2	57	2	59	624.912
#3	BNC1	54	4	58	64.935
#4	MITF	53	9	62	1444.238
#5	GATA3	52	7	59	199.143
#6	TP63	49	0	49	0
#7	RXRA	48	9	57	256.815
#8	ETS2	47	9	56	771.789
#9	IRX2	45	10	55	1038.679
#10	TRIM29	43	3	46	750.484
#11	PRDM1	43	7	50	1145.363
#12	KLF5	42	10	52	611.854
#13	ALX1	42	8	50	14337.663
#14	IRX4	41	7	48	2157.593
#15	FBXW7	40	7	47	234.65
#16	C1orf85	40	10	50	7516.015
#17	NFIA	39	6	45	740.122
#18	SOX15	39	10	49	461.056
#19	TFAP2B	37	7	44	465.953
#20	SOX7	37	8	45	240.539
#21	EHF	36	5	41	62.508
#22	GRHL3	34	7	41	810.268
#23	POU2F3	34	9	43	701.7
#24	HOXB7	34	10	44	14813.09
#25	FOXD3	34	15	49	18399.841
#26	DLX3	34	10	44	453.181
#27	MAX	34	1	35	110.999
#28	FOXQ1	33	6	39	2743.115
#29	HMG20B	33	4	37	449.898
#30	CEBPA	33	15	48	889.077
#31	FOXN3	33	7	40	1038.062
#32	IRF6	33	3	36	66.287
#33	JUN	32	9	41	509.453
#34	TP53	32	9	41	1763.972
#35	ZFP36L2	31	3	34	755.028
#36	HEY1	31	13	44	403.444
#37	NFIX	31	9	40	412.968
#38	JUND	30	5	35	9040.988
#39	SIX1	29	12	41	593.672
#40	FOXP1	29	11	40	1768.392
#41	KLF4	29	4	33	5172.275
#42	MEF2C	29	12	41	7375.147
#43	HLF	29	10	39	1161.033
#44	BHLHE40	29	5	34	1357.123
#45	GLI2	28	7	35	607.89
#46	ETV1	27	10	37	3693.207
#47	TCF12	27	9	36	3228.876
#48	CREB1	27	14	41	2848.901
#49	HOPX	27	6	33	70.793
#50	SOX10	26	11	37	1691.673
#51	HES6	26	8	34	1463.716
#52	NR1H2	25	3	28	264.855
#53	HR	25	13	38	446.172
#54	ARNTL	25	8	33	3340.833
#55	OVOL1	25	4	29	52.175
#56	ARNT2	25	15	40	1794.608
#57	JUNB	25	7	32	1514.956
#58	ZNF323	24	7	31	103.169
#59	ZNF165	24	12	36	3045.731
#60	ZEB1	24	11	35	3693.963
#61	TFE3	24	9	33	755.685
#62	SOX9	24	10	34	258.518
#63	HSF1	24	8	32	2345.668
#64	MAFB	24	9	33	491.551
#65	ENO1	24	3	27	150.46
#66	HOXB2	24	9	33	250.157
#67	SATB1	23	12	35	2211.708
#68	NFIC	23	11	34	1165.233
#69	THRB	22	12	34	8586.145
#70	ETV4	22	10	32	4489.449
#71	GTF2H2	22	15	37	4861.129
#72	ZNF117	22	13	35	1596.238
#73	PITX1	22	11	33	1224.386
#74	RORA	22	7	29	462.71
#75	NFATC3	22	6	28	2789.385
#76	GAS7	22	7	29	1588.478
#77	BACH2	21	11	32	666.209
#78	NFAT5	21	10	31	1141.225
#79	HOXB6	21	7	28	284.966
#80	TCF4	21	11	32	2503.362
#81	ZNF91	21	11	32	477.304
#82	CREB5	21	10	31	1793.349
#83	EBF1	21	15	36	5434.802
#84	TULP4	21	14	35	1539.84
#85	EGR3	21	10	31	915.091
#86	SOX4	21	15	36	3910.222
#87	MYCL1	20	14	34	206.379
#88	HOXD13	20	10	30	818.511
#89	MYCN	20	8	28	228.204
#90	VDR	20	17	37	5997.629
#91	TRPS1	20	11	31	366.487
#92	TFCP2L1	20	13	33	349.532
#93	IRF4	20	6	26	778.926
#94	NR4A3	20	15	35	2450.42
#95	E2F7	20	14	34	2416.25
#96	VAV1	19	9	28	11675.587
#97	HOXC13	19	9	28	269.239
#98	SP140	19	12	31	961.816
#99	WNT5A	19	13	32	760.33
#100	HCLS1	19	8	27	1195.288
#101	TCF3	19	10	29	1776.232
#102	ETV7	18	11	29	927.953
#103	FOXM1	18	11	29	8376.414
#104	BCL6	18	12	30	368.57
#105	RXRB	18	9	27	272.509
#106	FOXE1	18	13	31	927.727
#107	ARNTL2	18	10	28	411.748
#108	TEAD2	18	16	34	3398.871
#109	MEOX2	17	12	29	1647.486
#110	LHX2	17	10	27	942.462
#111	ZFHX3	17	10	27	389.787
#112	FOXC1	17	15	32	754.02
#113	NR2C1	17	13	30	2495.387
#114	EN2	17	14	31	9537.244
#115	TBX1	17	10	27	1300.095
#116	LEF1	16	13	29	208.09
#117	TFAP2C	16	18	34	2074.431
#118	FOXO6	16	12	28	748.989
#119	NR0B1	16	11	27	804.028
#120	IKZF1	16	10	26	3319.904
#121	TWIST1	16	10	26	1354.093
#122	NFATC2	16	14	30	3162.847
#123	SMAD1	16	18	34	3356.482
#124	RUNX3	16	11	27	17191.194
#125	CREB3L2	16	8	24	692.758
#126	SMAD5	16	12	28	1502.382
#127	RUNX1T1	15	15	30	860.519
#128	TRERF1	15	8	23	624.009
#129	FOSL2	15	10	25	455.23
#130	NANOGNB	15	11	26	905.991
#131	AEBP1	15	16	31	1504.636
#132	ZNF135	15	8	23	839.911
#133	RUNX1	15	13	28	1043.331
#134	MZF1	15	14	29	2878.907
#135	HOXB9	15	14	29	2683.919
#136	NR2F2	15	13	28	2728.199
#137	MAF	15	9	24	752.95
#138	IRX5	15	6	21	176.093
#139	SPEN	15	11	26	1596.685
#140	KLF15	15	9	24	922.862
#141	POU3F1	15	9	24	170.466
#142	SCML1	15	10	25	3556.36
#143	DLX1	15	13	28	1438.517
#144	NR4A2	14	15	29	1619.184
#145	ZNF37A	14	10	24	765.363
#146	POU4F1	14	10	24	729.652
#147	MMP14	14	9	23	875.842
#148	NFIB	14	14	28	2045.37
#149	FOXO3	14	11	25	584.982
#150	TFAP2A	14	13	27	3165.511
#151	TADA2A	14	16	30	1457.22
#152	TRIM22	14	10	24	565.796
#153	IRX3	14	9	23	457.661
#154	HOXB3	14	7	21	349.602
#155	ZEB2	14	9	23	402.645
#156	KDM5A	14	16	30	654.136
#157	TFDP2	13	16	29	1989.545
#158	EGR1	13	10	23	352.343
#159	HMGA1	13	16	29	1230.25
#160	UHRF1	13	9	22	3092.339
#161	SOX5	13	11	24	195.302
#162	ZNF75D	13	14	27	648.403
#163	PPARD	13	11	24	514.952
#164	FOXD1	13	17	30	4873.797
#165	CUX2	13	14	27	499.29
#166	NR2E1	13	9	22	684.495
#167	MYF6	13	10	23	1592.913
#168	CSRNP3	13	15	28	5671.44
#169	ASCL2	13	9	22	118.536
#170	CTNNB1	13	12	25	1444.602
#171	ETV5	13	15	28	1208.636
#172	PKNOX2	13	17	30	2931.189
#173	GATAD2B	13	13	26	1943.336
#174	TWIST2	13	9	22	223.404
#175	NPAS2	13	15	28	1961.759
#176	CITED1	12	15	27	319.763
#177	TFEC	12	9	21	622.026
#178	GTF2H4	12	7	19	522.155
#179	DLX2	12	13	25	1194.795
#180	ZSCAN20	12	11	23	716.991
#181	TCF20	12	11	23	445.715
#182	MTA2	12	12	24	2491.588
#183	FOXN1	12	11	23	1349.725
#184	MEOX1	12	17	29	1435.63
#185	BATF	12	17	29	8931.241
#186	LZTS1	12	11	23	1544.216
#187	TCF7	12	12	24	1766.717
#188	PGR	12	9	21	844.399
#189	FOXP4	12	12	24	527.217
#190	GLI3	12	16	28	1621.021
#191	WT1	12	12	24	2255.379
#192	ELF5	11	8	19	79.352
#193	HOXB8	11	16	27	500.969
#194	FOXP3	11	14	25	1077.592
#195	STAT1	11	9	20	687.307
#196	PAX4	11	12	23	3674.626
#197	ZHX2	11	14	25	3919.339
#198	SOX18	11	13	24	531.45
#199	ZNF238	11	15	26	2016.089
#200	TP73	11	12	23	224.892
#201	ZNF83	11	13	24	1791.469
#202	ETS1	11	12	23	1311.555
#203	POU3F2	11	13	24	179.634
#204	PRRX2	11	15	26	3236.161
#205	PLAG1	11	12	23	730.73
#206	HOXD1	11	10	21	1924.002
#207	NFE2L3	11	16	27	2967.204
#208	ZNF207	11	11	22	2522.007
#209	SIN3A	11	13	24	3402.244
#210	NR2F6	11	19	30	2330.646
#211	CREB3L1	11	9	20	484.36
#212	C12orf28	11	8	19	70.363
#213	TSHZ2	11	15	26	511.819
#214	ZBTB38	11	15	26	1007.089
#215	ZNF193	11	18	29	11607.583
#216	ZXDC	11	16	27	2073.134
#217	NR4A1	11	15	26	309.851
#218	ZFP42	11	9	20	318.902
#219	ZNF3	11	7	18	1000.295
#220	RXRG	11	12	23	1517.802
#221	SATB2	11	9	20	407.421
#222	PHF1	10	12	22	1129.004
#223	ATF7	10	11	21	1020.488
#224	HIC1	10	13	23	1248.215
#225	TEF	10	14	24	2129.725
#226	ATF2	10	17	27	829.214
#227	HHEX	10	17	27	1300.146
#228	MYBL2	10	14	24	2536.525
#229	ESR1	10	19	29	403.436
#230	E2F5	10	20	30	611.082
#231	PKNOX1	10	14	24	1309.718
#232	MBD1	10	12	22	1098.677
#233	FOXP2	10	18	28	1153.799
#234	ONECUT1	10	10	20	294.705
#235	ZNF85	10	15	25	3785.128
#236	CDKN2A	10	16	26	4582.302
#237	SIX5	10	16	26	1355.082
#238	PITX2	10	19	29	816.46
#239	SNAI3	10	9	19	1868.659
#240	ARNT	10	10	20	745.502
#241	ZNF131	10	11	21	394.078
#242	HOXD3	10	12	22	518.182
#243	HOXA4	10	7	17	479.006
#244	ZNF449	9	9	18	870.854
#245	OLIG2	9	15	24	2469.572
#246	HOXA3	9	10	19	575.173
#247	HOXA5	9	12	21	3035.05
#248	LMO4	9	11	20	236.583
#249	TAF13	9	11	20	1808.15
#250	NFE2L2	9	15	24	897.709
#251	HEY2	9	18	27	635.428
#252	ONECUT2	9	14	23	1050.519
#253	SOX8	9	14	23	800.679
#254	ZNF287	9	13	22	639.43
#255	MEIS1	9	18	27	1454.66
#256	KCNH8	9	13	22	1766.675
#257	HSF4	9	14	23	5410.429
#258	STAT2	9	14	23	1235.349
#259	RUNX2	9	18	27	1783.188
#260	EVX1	9	13	22	4536.191
#261	POU2F1	9	13	22	1570.65
#262	HOXC5	9	15	24	1190.856
#263	MLL	9	17	26	2518.79
#264	GATAD1	9	12	21	791.786
#265	HOXA13	9	11	20	280.004
#266	IRF1	9	11	20	404.155
#267	NPAS1	9	17	26	1375.638
#268	NR3C2	8	17	25	7522.637
#269	SLC2A4RG	8	11	19	2298.081
#270	ELF4	8	18	26	2079.675
#271	NFATC4	8	11	19	454.105
#272	SIX4	8	16	24	1000.587
#273	HOXB13	8	14	22	950.853
#274	HMGA2	8	12	20	666.459
#275	MLXIPL	8	20	28	1720.986
#276	DLX6	8	13	21	871.697
#277	NEUROD1	8	14	22	2414.617
#278	ZNF174	8	17	25	2343.573
#279	IRX1	8	15	23	323.52
#280	BTG2	8	17	25	463.635
#281	VTN	8	12	20	803.143
#282	RORC	8	16	24	991.849
#283	NANOG	8	11	19	269.244
#284	ZIC1	8	17	25	3139.986
#285	HESX1	8	16	24	2228.683
#286	MLLT10	8	12	20	538.511
#287	ZIC2	8	12	20	1927.564
#288	HOXA1	8	20	28	1946.822
#289	ZNF24	8	10	18	734.408
#290	SIM2	8	11	19	493.367
#291	ZNF41	8	11	19	609.613
#292	TAL1	7	14	21	4046.69
#293	TBX2	7	10	17	572.315
#294	STAT5B	7	15	22	1087.291
#295	PRRX1	7	11	18	534.039
#296	ZNF33B	7	13	20	1052.258
#297	RORB	7	11	18	336
#298	SOX13	7	15	22	315.793
#299	SOX2	7	15	22	7093.378
#300	PAX7	7	15	22	1777.651
#301	RFX3	7	14	21	686.592
#302	TBX3	7	19	26	2031.424
#303	SOX11	7	12	19	842.644
#304	ZNF167	7	11	18	308.68
#305	FOXG1	7	13	20	1076.34
#306	FOXK2	7	16	23	1527.723
#307	ZSCAN2	7	13	20	478.051
#308	NR1H4	7	13	20	1553.657
#309	MESP1	7	15	22	398.79
#310	POU6F1	7	12	19	3218.037
#311	AFF4	7	12	19	2735.205
#312	ZSCAN12	7	14	21	1946.552
#313	TBX5	7	15	22	936.613
#314	SIM1	7	15	22	788.202
#315	STRN3	7	12	19	363.544
#316	SUPT6H	7	13	20	2788.815
#317	ZIC5	7	8	15	2151.447
#318	MYT1	7	12	19	591.498
#319	ZSCAN18	7	12	19	821.293
#320	PAX3	7	13	20	327.14
#321	PAX6	7	12	19	194.129
#322	NKX3-2	7	18	25	1211.015
#323	SOX30	7	15	22	500.616
#324	MXD1	7	13	20	182.47
#325	MNX1	7	14	21	430.457
#326	KLF16	7	17	24	1652.814
#327	HOXD4	7	14	21	810.53
#328	ZNF444	7	17	24	2801.982
#329	GATA6	6	17	23	599.167
#330	GATA4	6	14	20	410.125
#331	MKX	6	14	20	1607.223
#332	SPIC	6	13	19	1779.965
#333	POU1F1	6	12	18	511.83
#334	ZNF277	6	18	24	1382.51
#335	NFE2	6	12	18	95.123
#336	KLF12	6	16	22	701.077
#337	FOXL1	6	10	16	336.756
#338	BARHL1	6	13	19	679.712
#339	BCL3	6	11	17	190.68
#340	POU3F3	6	14	20	383.033
#341	ELF3	6	11	17	229.836
#342	AHCTF1	6	11	17	5031.177
#343	LASS6	6	13	19	968.247
#344	SOX6	6	11	17	688.841
#345	HOXA2	6	11	17	601.077
#346	ESRRB	6	11	17	1224.019
#347	ESRRG	6	21	27	3480.746
#348	NFX1	6	13	19	285.879
#349	FOXL2	6	13	19	716.549
#350	C11orf9	6	12	18	304.394
#351	RARA	6	11	17	1646.98
#352	NFKB2	6	13	19	757.116
#353	RFXAP	6	13	19	704.966
#354	ANKRD30A	6	14	20	692.788
#355	PBX4	6	16	22	963.295
#356	HES5	6	7	13	173.994
#357	ISL1	6	17	23	1594.929
#358	CREM	6	16	22	875.441
#359	KLF6	6	9	15	264.261
#360	GLIS3	6	11	17	723.073
#361	ST18	6	16	22	2351.657
#362	NR5A2	6	18	24	2067.101
#363	ZFHX4	6	8	14	849.6
#364	FOXC2	6	16	22	1518.825
#365	ZNF639	6	16	22	2092.251
#366	TLX2	6	13	19	449.036
#367	TGIF1	6	16	22	634.65
#368	LHX6	6	12	18	610.958
#369	ZNF90	6	15	21	1693.854
#370	ELK1	6	15	21	1069.252
#371	SOX21	6	14	20	1436.439
#372	ZNF496	6	8	14	2272.213
#373	POU2F2	6	12	18	494.858
#374	BARX1	6	12	18	1179.003
#375	SCRT1	6	16	22	617.715
#376	HIRA	6	13	19	1521.313
#377	SREBF1	6	14	20	1151.112
#378	YY1	6	12	18	2132.027
#379	HMGB2	6	13	19	1492.111
#380	ISL2	6	13	19	523.874
#381	ERG	6	10	16	553.475
#382	TBX6	6	15	21	10552.249
#383	HOXA10	6	15	21	597.686
#384	ISX	5	13	18	755.242
#385	HNF4G	5	14	19	572.01
#386	NPAT	5	13	18	576.863
#387	HOXD11	5	14	19	931.908
#388	CREBZF	5	17	22	1936.188
#389	DMBX1	5	10	15	1421.001
#390	FOXO1	5	15	20	551.28
#391	PPARG	5	21	26	3146.939
#392	ZNF500	5	12	17	1437.085
#393	THRA	5	12	17	244.902
#394	NR5A1	5	15	20	704.712
#395	BLZF1	5	11	16	1070.972
#396	NKX2-8	5	15	20	2355.29
#397	FOSL1	5	17	22	887.773
#398	NCOR1	5	13	18	1598.502
#399	SMAD2	5	13	18	406.287
#400	SALL1	5	18	23	2188.497
#401	NFATC1	5	14	19	1019.217
#402	SOX1	5	15	20	1720.536
#403	SMAD3	5	13	18	375.031
#404	TFDP1	5	18	23	1679.823
#405	TCF7L2	5	13	18	742.374
#406	ESR2	5	12	17	1483.98
#407	FUBP1	5	14	19	853.25
#408	PCGF2	5	10	15	813.166
#409	TCF21	5	9	14	595.7
#410	NKX6-2	5	16	21	673.556
#411	SMAD4	5	17	22	1304.482
#412	ZNF483	5	10	15	1035.552
#413	MECOM	5	13	18	692.687
#414	RCAN1	5	13	18	766.453
#415	PPARA	5	14	19	4325.917
#416	GBX2	5	13	18	387.483
#417	RAX2	5	15	20	2381.622
#418	IKZF3	5	10	15	277.278
#419	CTBP1	5	14	19	1300.398
#420	ATF6B	5	15	20	984.059
#421	HOXB1	4	16	20	2211.032
#422	HOXA9	4	12	16	818.561
#423	ESX1	4	8	12	796.769
#424	ZSCAN23	4	14	18	349.187
#425	FOSB	4	11	15	725.953
#426	ELK4	4	16	20	1591.972
#427	RCOR1	4	16	20	1220.314
#428	SIX3	4	18	22	470.223
#429	REST	4	12	16	1130.252
#430	EGR2	4	14	18	202.98
#431	GATA5	4	11	15	557.282
#432	ZNF93	4	13	17	453.671
#433	LMX1A	4	9	13	1009.039
#434	KLF9	4	18	22	1731.135
#435	ZNF81	4	13	17	2447.452
#436	HOXA11	4	12	16	138.228
#437	ZNF19	4	13	17	1412.865
#438	HNRNPAB	4	13	17	906.236
#439	OTX2	4	10	14	514.537
#440	SPDEF	4	12	16	2843.87
#441	PBX1	4	14	18	174.385
#442	LHX9	4	16	20	576.031
#443	SPI1	4	16	20	921.03
#444	DMRT2	4	14	18	1054.462
#445	ZNF396	4	18	22	553.325
#446	USF1	4	18	22	2509.887
#447	GSC2	4	9	13	450.55
#448	TEAD1	3	10	13	657.933
#449	FLI1	3	12	15	319.067
#450	ZNF215	3	17	20	475.47
#451	NRL	3	15	18	653.329
#452	MSX2	3	13	16	3274.711
#453	TBX20	3	14	17	1027.964
#454	MYNN	3	14	17	775.524
#455	SPIB	3	16	19	1213.178
#456	HOXD10	3	8	11	2974.648
#457	TADA3	3	11	14	186.75
#458	ALX3	3	15	18	542.51
#459	FOXA1	3	14	17	298.991
#460	ERF	3	13	16	1259.134
#461	HOXA7	3	14	17	1225.321
#462	SLC26A3	3	13	16	912.289
#463	ARX	3	10	13	205.816
#464	SMAD6	3	6	9	385.243
#465	HIF3A	3	14	17	1044.822
#466	EGR4	3	16	19	408.184
#467	FOS	3	14	17	875.032
#468	POU6F2	3	12	15	389.953
#469	PLSCR1	3	17	20	434.346
#470	KDM5B	3	13	16	493.218
#471	ALS2CR8	3	13	16	1456.403
#472	MGA	3	14	17	566.437
#473	VSX1	2	16	18	1784.688
#474	ZNF80	2	13	15	824.122
#475	LHX8	2	20	22	621.082
#476	ZFP36L1	2	18	20	1297.411
#477	ASCL1	2	13	15	711.646
#478	SCAND2	2	13	15	389.266
#479	GCM1	2	12	14	1362.337
#480	BHLHE41	2	22	24	211.738
#481	NKX2-3	2	19	21	345.205
#482	RERE	2	23	25	1074.261
#483	PEG3	2	11	13	284.137
#484	SNAPC5	2	12	14	747
#485	NEUROG1	2	17	19	698.876
#486	NFYA	1	13	14	119.292
#487	PTH	1	17	18	170.986
#488	HSF5	1	19	20	92.902
#489	TBX22	1	10	11	409.92
#490	PAX8	1	12	13	562.517
#491	NKX2-5	1	13	14	313.432
#492	NR6A1	1	15	16	228.685
#493	ZNF397	1	17	18	187.421
#494	PRDM2	1	15	16	816.877
#495	ZSCAN4	1	9	10	122.756
#496	MYF5	1	14	15	420.042
#497	LHX1	1	13	14	49.774
#498	ZFHX2	0	15	15	0
#499	MYT1L	0	15	15	0
#500	ZNF157	0	13	13	0