Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXA1	89	1	90	504.788
#2	SPDEF	76	2	78	1513.875
#3	AR	71	7	78	315.879
#4	FOXC1	71	3	74	20.406
#5	XBP1	71	1	72	4.418
#6	SNAI2	70	2	72	77.415
#7	ESR1	67	6	73	2272.978
#8	LMO4	63	13	76	1247.893
#9	FOXM1	61	6	67	558.368
#10	GATA3	61	5	66	2033.972
#11	EN1	58	7	65	2495.076
#12	NR2F1	58	17	75	1211.419
#13	SOX10	55	10	65	251.494
#14	ENO1	54	7	61	153.809
#15	RUNX3	54	6	60	775.14
#16	ZFHX4	53	7	60	257.496
#17	LASS6	53	12	65	1063.004
#18	BHLHE40	51	9	60	240.771
#19	IRF8	50	1	51	68.333
#20	TCF7L1	50	8	58	1945.395
#21	TCEAL1	50	10	60	936.231
#22	PCGF2	49	13	62	3010.055
#23	NFIL3	48	9	57	126.181
#24	HSF1	48	20	68	1051.918
#25	TSC22D3	48	20	68	794.113
#26	MEOX2	48	16	64	1305.072
#27	MAFB	48	11	59	319.299
#28	BACH2	47	14	61	1383.725
#29	BTG2	47	12	59	3519.257
#30	NFE2L3	47	8	55	373.616
#31	PTTG1	47	8	55	1182.298
#32	ZFP36L2	46	14	60	911.287
#33	SOX9	46	15	61	519.11
#34	AEBP1	46	4	50	199.911
#35	TFEC	45	7	52	1092.071
#36	TRIM22	45	4	49	121.896
#37	MEIS2	45	5	50	1063.55
#38	BCL11B	45	7	52	100.666
#39	STAT1	44	14	58	1014.199
#40	GATA6	44	17	61	1168.326
#41	MYBL2	43	9	52	632.619
#42	ZSCAN16	43	10	53	979.186
#43	PLSCR1	43	7	50	1331.347
#44	ZFPM2	42	8	50	1009.85
#45	ZNF91	42	14	56	234.58
#46	HOXB2	42	13	55	480.034
#47	CSDA	42	11	53	188.324
#48	IRF6	41	13	54	2990.999
#49	TBX3	41	14	55	1044.207
#50	ETV1	41	12	53	1229.7
#51	NR3C2	41	18	59	1274.594
#52	FOXO1	41	17	58	980.477
#53	CDKN2A	40	14	54	6623.759
#54	FLI1	39	8	47	2191.76
#55	SP140	39	11	50	2567.246
#56	HMBOX1	39	18	57	1447.73
#57	ZNF93	39	10	49	652.215
#58	SOX11	38	12	50	431.172
#59	TCF7L2	38	16	54	559.471
#60	EGR1	38	7	45	421.159
#61	JUND	38	11	49	282.91
#62	SPIB	38	12	50	194.989
#63	E2F8	38	12	50	454.054
#64	JUN	38	12	50	1281.293
#65	TCF12	37	12	49	838.813
#66	BHLHE41	37	11	48	315.686
#67	NR2F6	37	18	55	1541.948
#68	HEY2	36	20	56	419.045
#69	SMAD1	36	16	52	2435.221
#70	TP53	36	16	52	1170.297
#71	PRRX2	35	15	50	535.45
#72	ZFHX3	35	19	54	989.446
#73	HOXA5	35	7	42	166.871
#74	ZEB1	35	18	53	788.981
#75	TWIST1	34	13	47	2841.905
#76	IRF7	34	12	46	441.43
#77	EPAS1	34	18	52	1047.429
#78	BCL3	33	14	47	1291.158
#79	TEAD4	33	13	46	246.422
#80	HOXD4	33	13	46	585.539
#81	MYC	33	21	54	717.954
#82	NFATC3	32	15	47	697.563
#83	HHEX	32	14	46	569.092
#84	NFIB	32	24	56	1211.023
#85	CEBPA	32	19	51	1618.521
#86	TEAD1	32	15	47	873.448
#87	HEY1	32	16	48	632.881
#88	ARNTL2	32	14	46	826.079
#89	MEOX1	32	17	49	769.716
#90	E2F5	32	20	52	1510.051
#91	ZNF165	31	28	59	957.827
#92	RORC	31	14	45	193.251
#93	SLC26A3	31	22	53	490.309
#94	RXRB	31	18	49	2089.607
#95	TRPS1	31	11	42	944.588
#96	HLF	31	18	49	316.184
#97	HOXA7	31	14	45	670.356
#98	MEF2C	31	20	51	954.017
#99	GATA2	31	11	42	105.948
#100	TFCP2L1	31	19	50	972.703
#101	ZEB2	30	19	49	775.761
#102	ELF5	30	8	38	50.093
#103	NR4A2	30	17	47	2208.655
#104	ARNT	30	19	49	1628.424
#105	MYCN	30	17	47	399.095
#106	ESRRG	29	19	48	995.218
#107	KLF5	29	15	44	1257.288
#108	STAT6	29	22	51	2029.286
#109	WNT5A	29	20	49	559.491
#110	IRX5	29	14	43	178.844
#111	ZNF323	29	20	49	804.891
#112	PBX1	29	14	43	1637.536
#113	EGR2	28	16	44	1146.727
#114	RARA	28	20	48	560.587
#115	SREBF1	28	15	43	123.855
#116	VAX2	28	14	42	503.035
#117	ZNF446	28	24	52	900.999
#118	ZFP37	28	28	56	1763.486
#119	GAS7	28	20	48	1007.005
#120	TCF4	28	14	42	200.091
#121	HOXC10	27	12	39	346.286
#122	HOXA10	27	21	48	1288.648
#123	HINFP	27	14	41	757.704
#124	ARNT2	27	22	49	772.656
#125	SATB1	27	23	50	837.626
#126	EGR3	27	13	40	1300.775
#127	NFIC	27	24	51	2231.636
#128	RXRA	27	18	45	1856.245
#129	EHF	27	24	51	1254.831
#130	SIX3	27	23	50	932.641
#131	ZNF434	26	17	43	603.435
#132	PLAG1	26	20	46	745.846
#133	TFAP2B	26	21	47	489.349
#134	GABPA	26	20	46	740.351
#135	ATF3	26	3	29	143.084
#136	ZNF167	26	24	50	754.182
#137	CBFA2T2	26	21	47	1154.652
#138	TBX19	26	17	43	435.457
#139	HOXA4	25	18	43	1621.874
#140	RORB	25	17	42	1344.11
#141	ZNF500	25	20	45	1339.184
#142	PGR	25	16	41	171.652
#143	GABPB1	25	19	44	1045.434
#144	NR1D2	25	19	44	1780.708
#145	TAF1B	25	18	43	1054.85
#146	NR4A3	25	18	43	435.783
#147	NKX3-1	24	26	50	983.349
#148	HOPX	24	24	48	698.926
#149	TBX2	24	20	44	1392.013
#150	ETV5	24	21	45	1165.001
#151	FOXF1	24	25	49	3425.31
#152	TSHZ2	24	22	46	729.106
#153	AFF4	24	23	47	1118.112
#154	ZBTB48	24	21	45	836.86
#155	FOSL1	23	22	45	1540.228
#156	PEG3	23	25	48	8059.582
#157	FOS	23	13	36	1675.904
#158	BATF3	23	23	46	562.969
#159	IKZF1	23	19	42	971.721
#160	ZIC1	23	18	41	406.014
#161	REL	23	20	43	969.579
#162	HOXC11	23	16	39	657.757
#163	PITX1	23	23	46	518.23
#164	DLX6	23	21	44	1185.42
#165	NFYA	23	25	48	983.131
#166	NFAT5	23	22	45	562.152
#167	FOXD1	23	23	46	427.216
#168	NANOG	22	22	44	593.725
#169	HOXA9	22	15	37	1375.114
#170	MSX2	22	18	40	286.075
#171	TRIM29	22	19	41	1901.019
#172	PAX6	22	19	41	944.705
#173	ISL1	22	28	50	1926.552
#174	HOXA2	22	18	40	929.242
#175	FOXC2	22	15	37	748.664
#176	TCF7	22	18	40	646.233
#177	HSF2	22	15	37	511.926
#178	SNAPC4	22	17	39	547.303
#179	HOXC5	22	23	45	962.99
#180	CEBPD	22	19	41	879.523
#181	MSC	22	18	40	1269.387
#182	SP1	22	18	40	1237.236
#183	ZGPAT	21	20	41	792.462
#184	NFIX	21	24	45	1030.642
#185	SIX2	21	23	44	1341.563
#186	EMX1	21	16	37	1006.905
#187	ALX1	21	27	48	2008.031
#188	LEF1	20	21	41	1180.327
#189	HMGA2	20	20	40	1179.254
#190	HOXB13	20	14	34	260.595
#191	MYF6	20	26	46	1061.54
#192	STRN3	20	15	35	594.168
#193	NFX1	20	18	38	1400.861
#194	NKX2-8	20	21	41	1380.986
#195	HR	20	15	35	392.765
#196	SPI1	20	22	42	629.716
#197	ZKSCAN1	20	16	36	1085.364
#198	IRX4	20	26	46	1716.4
#199	TADA2A	20	26	46	2210.744
#200	VENTX	20	25	45	894.875
#201	NKX3-2	20	16	36	638.02
#202	PPARG	20	20	40	1634.661
#203	PHF1	19	28	47	1266.394
#204	ZNF174	19	25	44	1158.153
#205	SCRT1	19	22	41	1518.582
#206	FOXO4	19	22	41	1051.317
#207	E2F4	19	21	40	938.738
#208	PROX1	19	21	40	1000.138
#209	CITED2	19	23	42	798.89
#210	NPAS2	19	20	39	338.645
#211	CREBBP	19	26	45	924.957
#212	ZNF268	19	17	36	522.982
#213	NR2E1	19	26	45	796.837
#214	TFAP2C	19	26	45	723.522
#215	HOXB6	19	14	33	222.014
#216	AHR	19	19	38	529.214
#217	CITED1	19	22	41	959.509
#218	PAX7	19	21	40	791.767
#219	SRY	19	26	45	1130.909
#220	TRIM25	19	22	41	1083.016
#221	E2F1	19	11	30	175.491
#222	MMP14	19	17	36	520.81
#223	ASCL1	19	23	42	631.916
#224	TLX1	19	17	36	503.891
#225	RORA	19	25	44	901.018
#226	SATB2	19	31	50	1810.521
#227	MLLT10	19	30	49	1511.733
#228	HCFC1	19	23	42	1062.359
#229	CREM	18	23	41	667.26
#230	ZNF643	18	27	45	1362.429
#231	FOSB	18	3	21	159.931
#232	HOXD11	18	27	45	1179.864
#233	ETV2	18	24	42	1129.438
#234	SCML1	18	25	43	835.341
#235	T	18	22	40	1387.064
#236	MLL	18	25	43	542.245
#237	KLF4	18	22	40	611.357
#238	AFF1	18	27	45	1435.343
#239	ZBTB17	18	25	43	1310.062
#240	FOSL2	18	24	42	1059.087
#241	THRB	18	23	41	877.235
#242	SMAD3	18	20	38	1857.87
#243	SALL1	18	33	51	3365.156
#244	CREB3L1	18	26	44	442.548
#245	TFDP3	18	25	43	978.123
#246	PITX2	18	22	40	871.97
#247	SIX1	18	26	44	1693.852
#248	HIC1	18	15	33	428.109
#249	TFAP2A	18	17	35	1432.079
#250	DLX2	17	25	42	970.007
#251	CEBPE	17	23	40	1176.194
#252	ELK3	17	23	40	1003.754
#253	SOX4	17	24	41	972.369
#254	BLZF1	17	26	43	912.764
#255	MEF2D	17	30	47	792.795
#256	PKNOX2	17	17	34	624.383
#257	FOXG1	17	25	42	426.319
#258	TP63	17	28	45	1205.629
#259	TCF15	17	26	43	1189.527
#260	HOXC13	17	15	32	375.829
#261	ZNF236	17	26	43	667.147
#262	WT1	17	24	41	879.25
#263	FOXN2	17	13	30	667.675
#264	TFAP4	17	20	37	752.522
#265	C2orf3	17	22	39	1367.802
#266	RUNX1T1	17	16	33	670.045
#267	MXD1	17	22	39	707.92
#268	KLF9	17	22	39	1299.23
#269	PURA	17	14	31	403.698
#270	NKX2-5	17	27	44	1224.078
#271	GATA4	16	22	38	1116.485
#272	MYT1	16	21	37	589.513
#273	PAX5	16	23	39	1553.417
#274	FOXA2	16	17	33	828.153
#275	ATF7	16	19	35	1092.339
#276	NR4A1	16	11	27	329.561
#277	CREB5	16	29	45	990.426
#278	ELF4	16	29	45	607.179
#279	PHOX2B	16	31	47	1051.438
#280	MNX1	16	22	38	562.029
#281	HOXB7	16	22	38	815.885
#282	KLF12	16	27	43	1149.826
#283	MYCL1	16	26	42	761.495
#284	MAX	16	23	39	817.656
#285	REST	16	24	40	721.525
#286	ONECUT2	16	21	37	921.795
#287	HOXC8	16	22	38	803.673
#288	ALX3	16	24	40	655.356
#289	TBX10	15	28	43	1002.653
#290	NKX6-1	15	21	36	790.566
#291	FOXE1	15	21	36	582.619
#292	ZNF192	15	15	30	1276.531
#293	NEUROD1	15	27	42	1986.389
#294	HOXA11	15	24	39	484.116
#295	SOX15	15	22	37	785.291
#296	ETV3	15	19	34	475.923
#297	FOXL2	15	26	41	913.61
#298	NR2F2	15	24	39	258.287
#299	ZNF80	15	35	50	1270.214
#300	HOXA1	15	25	40	470.516
#301	ZNF639	15	23	38	718.745
#302	SIM1	15	26	41	987.373
#303	FOXD3	15	18	33	720.154
#304	POU4F2	15	23	38	1198.939
#305	GCM1	15	28	43	2265.942
#306	ONECUT1	15	25	40	805.355
#307	POU3F4	15	20	35	632.537
#308	PRDM1	15	23	38	931.919
#309	ZSCAN18	15	17	32	477.144
#310	NPAS1	15	24	39	949.026
#311	HOXD9	15	25	40	1366.668
#312	SMAD6	15	28	43	831.262
#313	ZNF135	15	21	36	380.171
#314	MYOG	14	20	34	681.902
#315	ZNF132	14	18	32	604.041
#316	PHOX2A	14	23	37	938.665
#317	DMRT1	14	23	37	669.405
#318	FOXE3	14	22	36	381.55
#319	MZF1	14	30	44	838.979
#320	DLX4	14	21	35	1359.659
#321	HNF1B	14	23	37	1225.417
#322	RUNX2	14	30	44	1048.736
#323	ETS1	14	27	41	1487.037
#324	SNAPC5	14	26	40	1312.463
#325	CTBP1	14	22	36	768.741
#326	CUX2	14	26	40	901.167
#327	CLOCK	14	30	44	729.591
#328	ASCL2	14	27	41	919.338
#329	RB1	14	22	36	1160.115
#330	PPBPL2	14	17	31	675.358
#331	ZNF202	14	30	44	876.701
#332	SOX21	14	22	36	636.124
#333	ARID3A	14	16	30	1248.683
#334	SMAD4	14	17	31	296.22
#335	NR1I2	14	25	39	631.954
#336	HOXB9	13	21	34	1010.699
#337	CSRNP3	13	24	37	393.958
#338	RERE	13	24	37	658.79
#339	NFKB2	13	29	42	1102.723
#340	PTH	13	32	45	916
#341	ZNF444	13	22	35	478.326
#342	HES1	13	21	34	691.287
#343	FOXO3	13	30	43	2261.17
#344	HOXB3	13	18	31	436.352
#345	FUBP1	13	24	37	1426.737
#346	E2F2	13	18	31	463.352
#347	LHX2	13	21	34	163.754
#348	ATOH1	13	27	40	740.114
#349	EN2	13	22	35	318.517
#350	TBX4	13	27	40	746.142
#351	POU6F2	13	21	34	832.032
#352	TFEB	13	23	36	1184.871
#353	NR2C1	13	18	31	698.509
#354	HMGA1	13	30	43	2112.839
#355	PAX4	13	21	34	989.889
#356	BARX1	13	19	32	578.988
#357	ZNF155	13	23	36	894.009
#358	TP73	13	24	37	947.837
#359	GATA1	13	25	38	724.74
#360	NR5A2	13	22	35	807.985
#361	IRF4	13	26	39	1236.209
#362	RARB	12	28	40	839.664
#363	SOX5	12	21	33	455.094
#364	TBX5	12	27	39	616.926
#365	TSC22D2	12	21	33	470.259
#366	SCAND2	12	31	43	968.211
#367	HNF1A	12	24	36	513.991
#368	ZSCAN2	12	28	40	802.158
#369	HNF4G	12	24	36	1204.942
#370	NR1I3	12	24	36	697.772
#371	SOX18	12	30	42	769.315
#372	RBPJL	12	27	39	1089.434
#373	ELK1	12	23	35	292.341
#374	TADA3	12	27	39	421.505
#375	YY1	12	28	40	905.512
#376	THRA	12	25	37	1295.457
#377	RARG	12	29	41	985.883
#378	ZNF81	12	21	33	884.944
#379	HNF4A	12	24	36	1210.991
#380	VTN	12	26	38	1000.242
#381	HOXB1	12	22	34	697.457
#382	POU3F1	12	21	33	1040.698
#383	ZNF117	12	26	38	671.874
#384	TCF3	12	39	51	1237.086
#385	HOXD10	12	18	30	734.958
#386	RXRG	12	20	32	1392.034
#387	STAT2	12	20	32	729.962
#388	SIM2	12	21	33	329.775
#389	VDR	11	27	38	602.605
#390	HOXD13	11	25	36	647.903
#391	TAF13	11	29	40	917.304
#392	TBX1	11	32	43	573.105
#393	IKZF3	11	25	36	852.267
#394	RCAN1	11	26	37	1103.128
#395	ARNTL	11	22	33	861.981
#396	KLF15	11	26	37	633.902
#397	SRF	11	22	33	723.632
#398	SIX6	11	27	38	558.529
#399	ZIC3	11	26	37	913.532
#400	NFATC4	11	23	34	1486.892
#401	ZNF154	11	24	35	883.477
#402	ALX4	11	23	34	490.883
#403	PPARA	11	24	35	674.625
#404	LMX1B	11	26	37	603.077
#405	FOXI1	11	31	42	772.202
#406	OLIG2	11	28	39	1014.521
#407	NR2E3	11	24	35	756.127
#408	MTA2	11	27	38	775.474
#409	HOXA3	11	34	45	1143.2
#410	KLF1	11	24	35	708.649
#411	TLX2	11	31	42	890.345
#412	BUD31	11	23	34	420.879
#413	POU6F1	10	23	33	521.889
#414	MAF	10	30	40	398.333
#415	BNC1	10	25	35	435.304
#416	NEUROG1	10	27	37	1204.769
#417	SMAD9	10	24	34	942.251
#418	POU4F3	10	29	39	732.955
#419	NKX2-1	10	30	40	822.488
#420	ATF6B	10	21	31	959.224
#421	HESX1	10	28	38	772.373
#422	PAX8	10	27	37	652.051
#423	ESR2	10	27	37	683.132
#424	FOXP3	10	23	33	375.643
#425	LZTS1	10	28	38	549.251
#426	ZNF215	10	25	35	490.951
#427	NRL	10	27	37	668.278
#428	POU1F1	10	32	42	731.259
#429	TBX6	10	29	39	692.146
#430	ZFP36L1	9	28	37	810.477
#431	OVOL1	9	29	38	994.291
#432	HEYL	9	20	29	574.626
#433	ETV4	9	32	41	359.293
#434	ELK4	9	29	38	933.278
#435	NR0B1	9	31	40	662.414
#436	ZSCAN12	9	31	40	467.007
#437	NPAT	9	24	33	427.994
#438	MYT1L	9	23	32	589.593
#439	NR1H4	9	28	37	930.956
#440	NR5A1	9	31	40	1205.603
#441	HAND2	9	26	35	393.143
#442	POU3F2	9	21	30	908.085
#443	ZNF41	9	26	35	671.44
#444	PAX3	8	35	43	955.18
#445	C11orf9	8	27	35	948.931
#446	TCF21	8	23	31	254.632
#447	DBP	8	32	40	576.654
#448	TBR1	8	29	37	856.746
#449	POU3F3	8	32	40	799.539
#450	ZNF287	8	28	36	805.153
#451	KDM5B	8	25	33	433.113
#452	HOXB8	8	30	38	596.227
#453	EGR4	8	31	39	582.559
#454	TAL1	8	35	43	822.639
#455	FOXB1	8	26	34	759.002
#456	FOXJ1	8	28	36	1003.103
#457	ZNF157	8	30	38	523.407
#458	SOX2	8	26	34	807.599
#459	SP4	8	25	33	420.685
#460	FOXD2	8	27	35	446.328
#461	CREBZF	7	30	37	444.779
#462	PKNOX1	7	25	32	302.645
#463	POU2F3	7	33	40	577.64
#464	IRF5	7	16	23	207.283
#465	RFX3	7	25	32	364.342
#466	LHX1	7	28	35	384.149
#467	MLXIPL	7	24	31	421.649
#468	ST18	7	31	38	585.778
#469	SOX30	7	30	37	569.973
#470	PDX1	7	28	35	567.547
#471	TLX3	7	33	40	584.993
#472	ZNF238	7	29	36	1877.693
#473	POU2F2	7	23	30	349.179
#474	GSC2	7	31	38	481.08
#475	RAX	7	27	34	1165.798
#476	ATF5	7	23	30	569.172
#477	NR6A1	7	28	35	482.811
#478	PRDM2	7	28	35	383.271
#479	GBX2	6	24	30	430.659
#480	HOXD3	6	31	37	536.221
#481	NFE2	6	30	36	490.352
#482	HIF3A	6	26	32	444.873
#483	RFXAP	6	23	29	300.915
#484	GLI2	6	30	36	2179.292
#485	RUNX1	6	27	33	437.864
#486	MAFK	6	27	33	351.938
#487	HAND1	6	32	38	463.719
#488	POU4F1	6	26	32	144.153
#489	CRX	5	23	28	405.319
#490	MECOM	5	38	43	319.481
#491	ZHX3	5	20	25	261.56
#492	HMX1	5	29	34	321.776
#493	BRD8	5	30	35	486.252
#494	MYF5	5	26	31	357.36
#495	HOXD1	5	25	30	314.589
#496	NFATC1	4	23	27	434.87
#497	TEF	4	37	41	447.755
#498	PPARD	4	33	37	204.862
#499	FOXH1	4	23	27	200.724
#500	ZNF3	3	30	33	134.306