Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF131	64	7	71	1694.53
#2	RFX5	56	11	67	2208.19
#3	MMP14	48	8	56	882.439
#4	TCF3	43	6	49	1482.827
#5	ESRRA	43	9	52	841.515
#6	HMGA1	42	4	46	256.107
#7	KLF6	42	8	50	1014.31
#8	MAFB	41	6	47	553.272
#9	ATF1	41	5	46	682.16
#10	ETS1	40	10	50	1418.271
#11	HOXA3	40	9	49	1022.9
#12	MZF1	39	7	46	953.958
#13	NFE2L1	38	6	44	716.972
#14	FUBP1	38	5	43	304.226
#15	FOSB	38	0	38	0
#16	BUD31	37	3	40	301.34
#17	ZNF394	37	10	47	840.574
#18	TFEC	36	11	47	1591.865
#19	NR3C1	36	11	47	1470.259
#20	PHF1	35	11	46	1504.619
#21	EVX1	35	6	41	1162.682
#22	IRF8	35	5	40	175.229
#23	AFF1	35	9	44	1074.783
#24	ZNF219	35	11	46	1656.128
#25	TFAM	34	10	44	1000.195
#26	CEBPE	34	10	44	2175.536
#27	HDAC1	34	6	40	748.552
#28	TFAP2A	34	6	40	679.53
#29	JUN	33	5	38	374.606
#30	NKX3-2	33	10	43	935.114
#31	KLF2	33	4	37	364.234
#32	HSF1	32	12	44	1573.441
#33	SOX10	32	6	38	433.053
#34	TFDP3	32	12	44	1331.246
#35	MNT	32	8	40	925.152
#36	HEYL	31	9	40	520.255
#37	FOS	31	5	36	337.241
#38	EMX1	31	9	40	476.88
#39	POU3F3	31	9	40	963.739
#40	CSRNP3	30	11	41	1413.529
#41	TCF7L2	30	11	41	1440.798
#42	TEAD3	29	6	35	539.361
#43	ZNF217	29	13	42	880.653
#44	MYT1	29	12	41	1425.327
#45	TSC22D3	28	8	36	792.58
#46	BTG2	28	13	41	1363.052
#47	TARDBP	28	10	38	930.584
#48	FOXO1	28	16	44	1331.728
#49	TBX10	28	6	34	549.99
#50	CLOCK	27	10	37	1200.466
#51	STAT5A	27	10	37	1338.545
#52	BACH2	27	18	45	1332.58
#53	RUNX3	27	10	37	1189.516
#54	BHLHE41	27	13	40	1224.27
#55	E2F5	26	17	43	1642.464
#56	FOXH1	26	14	40	1718.367
#57	E2F4	26	9	35	470.538
#58	ZFP36L1	26	15	41	1045.017
#59	BLZF1	26	9	35	1000.735
#60	GABPB1	26	10	36	545.293
#61	KLF4	26	14	40	565.568
#62	BRD8	26	16	42	2091.483
#63	RELB	25	11	36	1177.018
#64	FOXA1	25	14	39	2301.773
#65	STAT3	25	16	41	1366.262
#66	KLF10	25	8	33	583.977
#67	GSC2	25	12	37	583.326
#68	KLF9	25	14	39	1317.361
#69	USF2	25	15	40	833.704
#70	CREB3L1	25	7	32	351.861
#71	HOXB2	24	6	30	743.402
#72	ALX4	24	21	45	1854.915
#73	SPIB	24	14	38	1855.582
#74	STAT2	24	12	36	1099.475
#75	ADNP2	24	13	37	948.649
#76	MEF2A	24	14	38	1740.502
#77	HHEX	24	10	34	843.912
#78	ZNF434	24	19	43	2560.596
#79	TAF12	24	17	41	1191.375
#80	ZSCAN16	23	19	42	1767.326
#81	CEBPA	23	9	32	402.049
#82	NFATC3	23	7	30	600.647
#83	BHLHE40	23	17	40	1024.34
#84	HIC1	23	11	34	933.506
#85	HOXB1	23	15	38	1450.806
#86	C11orf9	23	18	41	1979.968
#87	PDX1	23	10	33	1111.736
#88	ZNF444	23	15	38	1345.321
#89	TFE3	22	16	38	995.648
#90	POU2F2	22	13	35	668.42
#91	TP73	22	13	35	688.068
#92	ZEB2	22	11	33	569.014
#93	ZFP36L2	21	7	28	253.814
#94	IRX4	21	16	37	1417.738
#95	ATF3	21	12	33	1176.544
#96	ETV2	21	15	36	1159.855
#97	MXD1	21	7	28	1102.022
#98	HOXA5	21	13	34	783.917
#99	SPDEF	21	18	39	1496.369
#100	MYC	21	14	35	798.826
#101	MSX2	21	18	39	1199.902
#102	MAX	21	14	35	1108.84
#103	MGA	21	18	39	1259.234
#104	RORA	20	14	34	737.071
#105	RB1	20	12	32	1021.015
#106	TFDP2	20	15	35	1211.607
#107	NFKB2	20	19	39	1188.199
#108	DLX4	20	11	31	985.829
#109	NFIC	20	14	34	860.87
#110	NFYA	20	19	39	1203.437
#111	FOXP3	20	13	33	1701.698
#112	HIF1A	20	10	30	472.857
#113	NFYB	20	10	30	1570.85
#114	MAFF	20	18	38	2040.543
#115	STAT5B	20	9	29	1025.964
#116	SRF	20	11	31	677.31
#117	NR4A1	20	8	28	358.023
#118	REL	20	14	34	768.914
#119	HNF1A	19	10	29	675.007
#120	ZFHX3	19	14	33	721.215
#121	E4F1	19	13	32	655.476
#122	ZXDC	19	15	34	916.108
#123	NFATC1	19	13	32	1780.35
#124	NEUROD1	19	19	38	1137.363
#125	ERF	19	15	34	888.136
#126	HOXA4	19	15	34	1496.173
#127	MYF6	19	21	40	1104.42
#128	NR2F1	19	19	38	1387.815
#129	TADA3	19	8	27	869.262
#130	FOXA2	19	19	38	1973.066
#131	TCF12	19	15	34	768.923
#132	HOXB8	19	17	36	1037.781
#133	HOXD9	18	15	33	882.847
#134	PHTF1	18	15	33	889.113
#135	BCL3	18	24	42	1505.548
#136	TGIF1	18	13	31	350.862
#137	GLI3	18	13	31	535.923
#138	RBPJL	18	15	33	1630.54
#139	SOX17	18	12	30	652.811
#140	HSF2	18	9	27	902.74
#141	OVOL1	18	16	34	942.997
#142	LASS6	18	16	34	1264.122
#143	ZBTB17	18	7	25	579.794
#144	SLC2A4RG	18	14	32	965.792
#145	RUNX2	18	13	31	1167.08
#146	ZNF500	18	16	34	1403.637
#147	MLXIPL	18	19	37	965.779
#148	SUPT6H	18	16	34	635.997
#149	TFAP4	18	14	32	534.037
#150	IRX5	18	19	37	1145.458
#151	ZNF140	18	16	34	1104.627
#152	PPARG	17	15	32	582.223
#153	TWIST1	17	14	31	945.436
#154	HOXD4	17	16	33	1156.298
#155	FOXI1	17	16	33	1131.92
#156	FOXD2	17	15	32	1098.991
#157	KDM5B	17	17	34	2055.493
#158	MYF5	17	16	33	1223.221
#159	HNF1B	17	13	30	955.646
#160	E2F6	17	23	40	1554.638
#161	SOX11	17	14	31	1286.559
#162	PAX5	17	22	39	1232.523
#163	HEY2	17	9	26	504.26
#164	MLLT10	17	15	32	710.782
#165	HOXC10	17	16	33	1241.796
#166	PHOX2A	17	14	31	1123.83
#167	TCFL5	17	17	34	1151.049
#168	TCF4	17	20	37	1254.322
#169	GRHL2	17	20	37	1725.599
#170	AFF4	17	15	32	1609.131
#171	GATA1	17	19	36	1411.767
#172	CDKN2A	17	17	34	843.624
#173	GBX2	17	11	28	753.176
#174	SATB1	17	22	39	1734.416
#175	TBX4	16	11	27	597.936
#176	TFAP2C	16	13	29	872.806
#177	ASCL2	16	19	35	1185.271
#178	MYBL2	16	12	28	869.243
#179	NR0B1	16	20	36	1009.094
#180	KLF11	16	13	29	998.057
#181	IKZF1	16	16	32	787.55
#182	HMG20B	16	16	32	1434.03
#183	ETS2	16	11	27	504.552
#184	TEF	16	18	34	1448.322
#185	LHX5	16	12	28	996.428
#186	BCL6	16	18	34	983.216
#187	NR1I3	16	13	29	1274.65
#188	GTF2H3	16	17	33	1308.269
#189	ZNF135	16	10	26	503.32
#190	AEBP1	15	15	30	1123.356
#191	HNF4A	15	16	31	997.629
#192	PITX1	15	11	26	487.754
#193	MTF1	15	14	29	642.386
#194	MAF	15	12	27	673.495
#195	FOXM1	15	15	30	782.956
#196	MYCN	15	15	30	931.957
#197	NPAS1	15	19	34	999.663
#198	FOXO4	15	16	31	933.448
#199	ELK4	15	18	33	960.741
#200	NPAT	15	14	29	1144.765
#201	ZNF236	15	15	30	1223.179
#202	REXO4	15	17	32	882.233
#203	JUND	15	16	31	756.589
#204	FOXJ1	15	16	31	790.663
#205	PAX8	15	17	32	1263.937
#206	HINFP	15	18	33	781.852
#207	ZNF75D	15	11	26	778.09
#208	GTF2H4	15	15	30	1162.659
#209	ZNF91	15	12	27	918.129
#210	ESRRG	15	15	30	1096.352
#211	ELF4	15	15	30	1605.391
#212	ZKSCAN5	15	18	33	991.758
#213	ONECUT1	15	13	28	851.038
#214	MBD1	15	11	26	666.506
#215	REST	15	12	27	462.842
#216	LMO4	15	12	27	851.889
#217	EGR1	15	10	25	306.696
#218	FOSL1	15	14	29	689.891
#219	ELF2	14	12	26	736.045
#220	CREM	14	18	32	1114.704
#221	ESR1	14	15	29	958.569
#222	PRDM2	14	19	33	1230.096
#223	ZSCAN2	14	14	28	473.537
#224	T	14	18	32	952.499
#225	SMAD3	14	17	31	1056.199
#226	WT1	14	18	32	1407.183
#227	ZNF80	14	18	32	1154.596
#228	SMAD1	14	18	32	803.191
#229	FOXF1	14	15	29	1148.622
#230	ZBTB48	14	17	31	715.881
#231	ZNF268	14	19	33	1103.322
#232	HOXA11	14	12	26	929.046
#233	ZNF193	14	20	34	1232.862
#234	ZEB1	14	14	28	759.761
#235	ZNF154	14	13	27	680.028
#236	ZNF93	14	19	33	861.031
#237	CNOT8	14	12	26	779.531
#238	HOXA2	13	13	26	961.905
#239	ZNF165	13	16	29	783.09
#240	MEOX2	13	18	31	1255.068
#241	PKNOX1	13	17	30	1036.346
#242	TAF1B	13	21	34	923.135
#243	ELF5	13	20	33	1052.871
#244	MYT1L	13	13	26	499.355
#245	PPARD	13	10	23	667.996
#246	CUX2	13	14	27	1372.524
#247	NR4A2	13	13	26	363.216
#248	POU5F1B	13	20	33	851.676
#249	ATF5	13	18	31	1369.975
#250	ARNT2	13	16	29	1049.611
#251	THRA	13	18	31	1044.78
#252	NR2C1	13	10	23	667.189
#253	KLF15	13	15	28	1108.173
#254	GABPA	13	11	24	464.33
#255	POU6F1	13	18	31	1012.331
#256	STAT6	13	14	27	900.74
#257	NKX2-8	13	17	30	717.326
#258	NR2E1	13	11	24	616.186
#259	HOXA7	13	17	30	1010.255
#260	ELF1	13	14	27	375.014
#261	ZHX3	13	17	30	1008.293
#262	HOXD13	13	13	26	1242.979
#263	ZNF446	13	9	22	733.408
#264	ATF6B	13	16	29	896.166
#265	PKNOX2	13	15	28	1108.493
#266	GCM1	12	17	29	822.712
#267	CREBBP	12	19	31	1023.329
#268	ZNF83	12	12	24	522.527
#269	TCF21	12	19	31	1522.679
#270	TADA2A	12	16	28	1056.398
#271	GATA4	12	15	27	988.97
#272	SREBF1	12	18	30	678.629
#273	CITED2	12	9	21	875.839
#274	HIRA	12	20	32	643.99
#275	NFAT5	12	13	25	515.377
#276	GLI2	12	21	33	951.372
#277	SNAI2	12	16	28	492.26
#278	RXRB	12	15	27	710.3
#279	SNAPC4	12	14	26	726.885
#280	STAT1	12	13	25	610.629
#281	CSDA	12	18	30	684.357
#282	ZNF643	12	17	29	955.035
#283	SOX2	12	17	29	634.545
#284	ZGPAT	12	18	30	574.058
#285	KLF12	12	16	28	1066.147
#286	MEIS2	12	18	30	1783.559
#287	TRIM22	12	19	31	760.585
#288	MAFK	12	21	33	1179.42
#289	FOXG1	12	16	28	1057.087
#290	SCML1	12	20	32	964.755
#291	AHR	12	18	30	818.299
#292	LHX6	12	16	28	628.298
#293	ZNF174	12	15	27	716.55
#294	NR2F6	12	17	29	1065.939
#295	SOX5	12	14	26	853.441
#296	ELF3	12	18	30	1067.936
#297	MYOD1	12	17	29	714.351
#298	NKX2-5	12	14	26	910.515
#299	POU1F1	12	16	28	893.359
#300	ARNT	11	16	27	844.785
#301	IKZF3	11	17	28	836.304
#302	ARNTL2	11	19	30	685.678
#303	SATB2	11	20	31	869.353
#304	CBFA2T2	11	18	29	700.071
#305	PAX6	11	18	29	1180.385
#306	TCF7	11	18	29	796.582
#307	SP1	11	21	32	1235.58
#308	NR4A3	11	10	21	319.103
#309	HOPX	11	14	25	719.794
#310	LZTS1	11	13	24	1002.505
#311	TBX2	11	15	26	414.805
#312	SOX9	11	20	31	663.91
#313	NR1I2	11	18	29	832.36
#314	ELK1	11	17	28	659.742
#315	TRIM29	11	14	25	787.1
#316	HESX1	11	16	27	594.903
#317	HNF4G	11	11	22	594.16
#318	IRF5	11	21	32	794.613
#319	TAL1	11	18	29	950.572
#320	TSHZ2	11	16	27	1037.443
#321	LHX2	11	17	28	971.398
#322	NR5A1	11	12	23	475.761
#323	ZFPM2	11	16	27	1049.171
#324	ZNF175	11	14	25	507.447
#325	TP53	11	19	30	646.758
#326	TLX2	11	16	27	710.708
#327	POU3F2	11	17	28	720.431
#328	ISL1	11	22	33	906.639
#329	ZNF238	11	23	34	1114.945
#330	NR5A2	11	16	27	682.729
#331	NRL	11	19	30	874.943
#332	E2F8	11	16	27	1345.996
#333	ZNF134	11	15	26	661.377
#334	TAF13	10	21	31	1443.938
#335	TBX3	10	17	27	859.198
#336	FOXE1	10	19	29	712.294
#337	BATF3	10	19	29	758.083
#338	SIM2	10	18	28	799.551
#339	DLX6	10	13	23	536.726
#340	PAX7	10	13	23	458.101
#341	TFEB	10	21	31	830.93
#342	POU4F1	10	26	36	965.563
#343	ASCL1	10	19	29	999.098
#344	HLF	10	16	26	706.403
#345	SIX3	10	22	32	1210.325
#346	SIX1	10	17	27	711.697
#347	AR	10	15	25	569.638
#348	HOXC13	10	16	26	527.533
#349	ZSCAN18	10	22	32	844.354
#350	GATA3	10	19	29	963.713
#351	ATOH1	10	16	26	519.745
#352	HES1	10	18	28	1201.897
#353	VENTX	10	17	27	667.991
#354	TAF5	10	17	27	400.784
#355	EPAS1	10	25	35	895.646
#356	LEF1	10	18	28	716.76
#357	NFE2	10	15	25	500.783
#358	TSC22D2	10	17	27	659.154
#359	SALL1	10	19	29	763.757
#360	TBX19	9	17	26	739.787
#361	ZFP37	9	17	26	573.831
#362	ZNF45	9	21	30	650.189
#363	TP63	9	21	30	825.761
#364	PGR	9	17	26	801.904
#365	EN2	9	14	23	844.166
#366	TBX5	9	17	26	801.235
#367	BARX1	9	16	25	531.006
#368	RFXAP	9	16	25	892.985
#369	TBR1	9	17	26	733.076
#370	DLX2	9	16	25	752.372
#371	E2F2	9	19	28	833.68
#372	TLX3	9	23	32	1005.348
#373	NFATC4	9	12	21	565.815
#374	FOXD1	9	15	24	547.414
#375	FOXK2	9	21	30	1157.978
#376	PAX3	9	21	30	770.594
#377	VSX1	9	20	29	610.734
#378	CBL	9	20	29	964.093
#379	ZNF41	9	15	24	720.493
#380	GATA6	9	19	28	741.995
#381	ONECUT2	9	12	21	461.643
#382	PLSCR1	9	18	27	720.959
#383	ESR2	9	17	26	518.873
#384	NFIB	9	22	31	740.369
#385	PTH	9	17	26	951.106
#386	SRY	9	20	29	819.313
#387	SIX2	9	17	26	541.358
#388	RCAN1	9	17	26	637.816
#389	PBX1	9	21	30	851.753
#390	ZNF277	9	17	26	799.783
#391	HOXD11	8	15	23	562.133
#392	SLC26A3	8	18	26	993.763
#393	CEBPD	8	22	30	841.025
#394	HOXD3	8	17	25	483.488
#395	RBCK1	8	16	24	383.632
#396	ZNF155	8	21	29	770.286
#397	FOSL2	8	17	25	474.154
#398	VTN	8	18	26	523.031
#399	MNX1	8	18	26	672.085
#400	PROX1	8	19	27	750.49
#401	RUNX1	8	20	28	803.383
#402	SIM1	8	15	23	602.915
#403	BNC1	8	15	23	524.902
#404	FOXB1	8	20	28	625.012
#405	TBX6	8	19	27	555.628
#406	SCAND2	8	19	27	552.073
#407	POU6F2	8	16	24	306.637
#408	SNAPC5	8	21	29	1045.684
#409	NANOG	8	14	22	489.546
#410	RXRA	8	19	27	472.747
#411	PITX2	8	18	26	880.102
#412	OLIG2	8	13	21	535.325
#413	RORC	8	12	20	373.087
#414	KLF5	8	19	27	822.963
#415	ST18	8	18	26	681.88
#416	IRF4	8	23	31	794.734
#417	TFDP1	8	9	17	235.934
#418	RUNX1T1	8	20	28	758.458
#419	SOX18	8	19	27	865.228
#420	RERE	8	23	31	672.312
#421	POU2F3	8	15	23	889.694
#422	MLL	8	17	25	399.741
#423	ZNF81	8	19	27	819.079
#424	ARNTL	8	21	29	800.549
#425	ZNF3	8	18	26	1225.231
#426	ATF6	8	22	30	777.13
#427	MSRB2	8	18	26	844.857
#428	MTA2	7	12	19	524.104
#429	ZIC3	7	15	22	586.136
#430	GAS7	7	13	20	291.522
#431	DMRT1	7	18	25	726.181
#432	EN1	7	17	24	410.171
#433	TEAD4	7	19	26	557.392
#434	C2orf3	7	16	23	646.821
#435	POU3F1	7	15	22	292.611
#436	NPAS2	7	17	24	731.301
#437	DBP	7	15	22	614.855
#438	RARA	7	17	24	323.477
#439	ZNF323	7	19	26	653.917
#440	HOXB7	7	17	24	425.198
#441	SMAD6	7	21	28	520.506
#442	ZSCAN12	7	17	24	531.663
#443	ZNF639	7	13	20	440.833
#444	PPBPL2	7	19	26	830.997
#445	TEAD1	7	20	27	915.335
#446	NFX1	7	17	24	463.632
#447	PAX4	7	17	24	564.814
#448	YY1	7	16	23	469.414
#449	RARG	7	22	29	802.289
#450	TRPS1	7	17	24	351.032
#451	SOX30	7	14	21	941.994
#452	FOXD3	7	16	23	787.261
#453	SMAD5	7	16	23	444.002
#454	SOX21	7	15	22	307.251
#455	ZNF287	7	17	24	544.367
#456	HOXA9	7	14	21	519.235
#457	EHF	7	22	29	684.603
#458	ZNF215	7	19	26	370.235
#459	NR3C2	7	17	24	437.256
#460	SPI1	7	19	26	490.568
#461	HOXB9	6	19	25	421.501
#462	POU4F3	6	17	23	438.575
#463	CREB5	6	23	29	863.008
#464	CREBZF	6	20	26	698.389
#465	EGR2	6	19	25	453.172
#466	ZNF167	6	20	26	814.102
#467	HOXB6	6	19	25	457.204
#468	HIF3A	6	16	22	473.267
#469	ETV5	6	19	25	347.314
#470	ETV4	6	16	22	381.93
#471	NR2F2	6	16	22	266.797
#472	CRX	6	18	24	449.387
#473	SCRT1	6	11	17	287.578
#474	SOX4	6	16	22	575.786
#475	NEUROG1	6	18	24	487.597
#476	HOXA10	5	17	22	354.547
#477	RARB	5	17	22	359.57
#478	TBX1	5	17	22	517.752
#479	NR1H4	5	18	23	375.966
#480	NR6A1	5	15	20	496.406
#481	FOXC2	5	20	25	358.842
#482	ERG	5	22	27	462.183
#483	FOXO3	5	20	25	456.688
#484	NKX2-1	5	15	20	313.757
#485	PLAG1	5	25	30	409.128
#486	WNT5A	5	21	26	515.09
#487	MECOM	5	16	21	277.084
#488	ETV1	5	29	34	662.503
#489	HEY1	5	20	25	493.024
#490	MSX1	4	14	18	561.292
#491	ZIC1	4	12	16	191.523
#492	FOXL2	4	22	26	470.051
#493	HOXC8	4	23	27	385.646
#494	ZNF157	3	19	22	175.957
#495	EGR4	3	13	16	198.109
#496	HOXD1	2	18	20	270.045
#497	VDR	2	20	22	185.298
#498	TFAP2B	2	20	22	192.232
#499	PCGF2	1	18	19	86.182
#500	MEOX1	1	15	16	194.986