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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SOX6	65	4	69	2314.676
#2	NFIA	57	1	58	59.209
#3	MECOM	56	4	60	807.597
#4	HMGA2	50	5	55	3837.191
#5	KLF4	45	5	50	1259.423
#6	HLF	43	11	54	4228.251
#7	FOXQ1	40	11	51	876.124
#8	GATA6	40	8	48	413.142
#9	CEBPA	37	4	41	92.745
#10	NR3C2	36	3	39	81.559
#11	SOX2	35	6	41	2058.741
#12	TBX3	34	8	42	535.595
#13	TCF4	34	8	42	650.641
#14	HOXA10	32	8	40	304.767
#15	HOXA1	29	8	37	1654.699
#16	ONECUT2	28	9	37	762.363
#17	HOXA3	27	6	33	166.696
#18	PROX1	27	13	40	1810.894
#19	ZSCAN18	26	13	39	2861.974
#20	ASCL2	26	7	33	607.857
#21	HOXC10	26	11	37	688.572
#22	ETV1	26	4	30	1838.933
#23	THRB	26	2	28	57.308
#24	PBX1	26	10	36	625.543
#25	MEF2C	25	9	34	1382.662
#26	ALX1	25	6	31	117.701
#27	HOXC11	24	7	31	1071.164
#28	FOXA1	24	11	35	3078.613
#29	LHX2	24	15	39	948.55
#30	VTN	24	8	32	429.478
#31	TAF7	24	10	34	1285.604
#32	ZIC1	23	8	31	2136.734
#33	ZIC2	23	7	30	557.136
#34	TBX2	23	6	29	183.675
#35	L3MBTL4	23	7	30	2151.657
#36	IRF7	23	9	32	5745.233
#37	TEAD4	22	9	31	409.007
#38	NR1I2	22	11	33	4465.434
#39	HOXA5	22	12	34	331.308
#40	NR0B1	22	7	29	186.144
#41	HOXA4	22	9	31	241.21
#42	CREB3L1	21	14	35	3520.451
#43	TFCP2L1	21	9	30	930.084
#44	NR1H4	21	13	34	4242.593
#45	ZFP36L2	21	14	35	2942.718
#46	ZNF323	21	9	30	423.05
#47	STAT1	21	9	30	729.485
#48	FOXA2	21	10	31	873.924
#49	BHLHE41	20	12	32	2784.278
#50	FOXA3	20	5	25	569.737
#51	SCML1	20	8	28	1855.216
#52	ETV6	20	8	28	5455.147
#53	AHR	20	16	36	1922.124
#54	EGR1	20	11	31	1107.508
#55	IRF5	19	7	26	2633.278
#56	TRIM22	19	9	28	2013.365
#57	LEF1	19	11	30	427.085
#58	TBX4	19	10	29	295.941
#59	SALL1	19	7	26	466.7
#60	FOXP2	19	9	28	186.936
#61	POU2F2	18	11	29	1440.721
#62	PBX4	18	11	29	2576.964
#63	SIX4	18	10	28	890.422
#64	PITX1	18	12	30	458.444
#65	STAT4	17	11	28	5267.325
#66	SMAD9	17	11	28	1107.653
#67	AR	17	15	32	5203.855
#68	BATF	17	12	29	2676.118
#69	TCFL5	17	7	24	1195.435
#70	MAFF	17	13	30	965.667
#71	SPI1	17	14	31	2390.346
#72	ZEB2	17	11	28	3872.944
#73	HOXB7	17	11	28	2171.385
#74	FOS	17	11	28	1091.704
#75	IRF6	17	16	33	1292.238
#76	DLX2	17	10	27	1236.714
#77	NFE2L3	17	9	26	336.186
#78	ETS2	17	6	23	2621.962
#79	ZKSCAN1	16	11	27	1054.368
#80	NR2F1	16	8	24	2532.858
#81	SOX17	16	9	25	444.428
#82	SATB1	16	12	28	588.749
#83	RORC	16	12	28	381.62
#84	POU4F2	16	13	29	1363.238
#85	SCAND3	16	7	23	2013.316
#86	NR2F2	16	9	25	1631.769
#87	ARNTL	16	15	31	4134.83
#88	HOXB3	16	7	23	896.804
#89	HIRA	15	12	27	3459.413
#90	IRX3	15	13	28	230.412
#91	TEAD1	15	10	25	2162.728
#92	CLOCK	15	10	25	3256.535
#93	TFEB	15	12	27	1490.036
#94	E2F5	15	13	28	2669.348
#95	ETS1	15	10	25	1162.767
#96	KLF5	15	10	25	591.685
#97	BCL6	15	12	27	2086.629
#98	CSRNP3	15	14	29	2309.776
#99	TAF4B	15	12	27	1042.403
#100	SIM2	14	10	24	2488.89
#101	MNX1	14	9	23	528.829
#102	HOXA2	14	9	23	695.65
#103	WT1	14	12	26	2968.5
#104	SREBF1	14	10	24	867.412
#105	IRF4	14	6	20	386.876
#106	ST18	14	11	25	227.855
#107	KLF2	14	9	23	932.674
#108	SNAI3	14	10	24	2581.787
#109	KLF1	14	9	23	1641.6
#110	CREB5	14	13	27	4672.427
#111	ZNF438	14	12	26	411.777
#112	IRF1	14	11	25	6623.263
#113	SPIB	14	12	26	1661.118
#114	SOX4	14	13	27	1446.44
#115	NPAS2	14	11	25	354.297
#116	MSC	14	7	21	632.569
#117	FOXG1	14	14	28	1360.808
#118	EGR3	13	9	22	1670.998
#119	MAF	13	13	26	733.666
#120	CREB3L3	13	16	29	1835.08
#121	HEY1	13	14	27	647.777
#122	NR4A2	13	11	24	907.047
#123	PRDM1	13	10	23	1469.889
#124	HDX	13	14	27	1712.774
#125	ZNF165	13	8	21	562.418
#126	IRF8	13	11	24	848.399
#127	CBFA2T3	13	14	27	4201.128
#128	HOXA7	13	10	23	273.009
#129	ZSCAN12	13	10	23	1900.314
#130	NANOG	13	8	21	2864.079
#131	SLC2A4RG	13	13	26	1116.564
#132	TBX21	13	9	22	2713.308
#133	SCAND1	13	11	24	1322.513
#134	GATA2	13	11	24	996.752
#135	MYC	13	6	19	931.968
#136	MSX1	13	11	24	1237.06
#137	ZNF174	13	9	22	1771.847
#138	LHX9	12	10	22	2041.445
#139	VAV1	12	10	22	2515.782
#140	NOBOX	12	12	24	2467.359
#141	ZNF33B	12	11	23	952.32
#142	ZNF80	12	10	22	2035.02
#143	HOXD1	12	8	20	1175.83
#144	NEUROD1	12	7	19	1208.672
#145	HOXD10	12	7	19	1833.732
#146	MEIS1	12	9	21	1195.72
#147	ZNF483	12	12	24	2607.148
#148	TWIST1	12	11	23	1090.505
#149	ZNF83	12	6	18	937.666
#150	SIX1	12	14	26	2281.524
#151	CSDA	12	6	18	310.522
#152	ARNT2	12	13	25	3542.555
#153	ATF5	12	12	24	731.249
#154	TBX5	12	8	20	435.048
#155	HOXB6	12	14	26	774.496
#156	ARX	12	9	21	1779.088
#157	POU5F1B	11	12	23	2110.938
#158	TCF7L1	11	9	20	869.067
#159	FOXD3	11	13	24	3031.245
#160	MYT1	11	11	22	2574.341
#161	RORA	11	19	30	4797.436
#162	NKX2-8	11	7	18	929.27
#163	KLF15	11	6	17	164.474
#164	ONECUT1	11	9	20	2609.555
#165	ETV7	11	10	21	2025.244
#166	TFAP2A	11	12	23	2653.194
#167	SOX21	11	9	20	1254.486
#168	TCF7L2	11	9	20	613.878
#169	ELF4	11	10	21	1137.86
#170	SCAND2	11	9	20	484.574
#171	MSX2	11	7	18	135.553
#172	ZNF197	11	9	20	1297.742
#173	HOXC5	11	11	22	966.441
#174	FOSL1	11	13	24	701.163
#175	ZBTB48	11	13	24	359.502
#176	ZNF154	11	13	24	1278.61
#177	ZNF131	11	10	21	3924.199
#178	IKZF1	11	9	20	578.626
#179	HCLS1	11	12	23	1423.178
#180	PKNOX1	11	4	15	726.647
#181	HOXB2	11	9	20	804.897
#182	HOXA13	10	14	24	1893.932
#183	BATF3	10	9	19	868.993
#184	ATF2	10	11	21	1551.251
#185	NR6A1	10	10	20	270.798
#186	TAF13	10	7	17	647.827
#187	PRDM2	10	11	21	1172.369
#188	KLF7	10	10	20	1000.981
#189	HR	10	7	17	688.18
#190	ESRRG	10	12	22	515.309
#191	GATAD2A	10	16	26	2644.376
#192	HOXA11	10	7	17	140.881
#193	TP63	10	13	23	817.162
#194	ZNF167	10	11	21	1350.468
#195	FOXI1	10	14	24	1716.804
#196	SOX30	10	12	22	1642.422
#197	OVOL1	10	17	27	1878.322
#198	GCM1	10	9	19	1289.539
#199	POU5F2	10	13	23	1574.035
#200	PAX6	10	13	23	2957.571
#201	MYNN	10	12	22	2030.526
#202	TCF3	10	8	18	1727.29
#203	EBF1	10	11	21	1463.155
#204	GATA5	10	13	23	1548.935
#205	PPARD	10	12	22	6063.643
#206	FOXL1	10	10	20	1600.786
#207	TBX15	10	11	21	1714.002
#208	ZNF446	10	10	20	414.052
#209	RFXAP	10	13	23	844.058
#210	POU3F1	10	6	16	1326.153
#211	RARB	10	9	19	483.816
#212	TADA3	10	6	16	1017.764
#213	TFAP2C	10	10	20	810.192
#214	MSRB2	10	9	19	503.986
#215	ESR1	10	9	19	923.635
#216	MIXL1	9	7	16	665.882
#217	ZNF193	9	10	19	802.34
#218	C11orf9	9	10	19	1040.16
#219	HOXD8	9	10	19	1229.26
#220	BATF2	9	10	19	1270.9
#221	ALX3	9	11	20	1459.818
#222	TEAD2	9	11	20	1486.689
#223	ARNTL2	9	10	19	1534.639
#224	FUBP1	9	8	17	977.064
#225	LHX8	9	15	24	444.895
#226	MKX	9	9	18	329.46
#227	DMRT1	9	9	18	952.604
#228	ZNF287	9	13	22	1584.313
#229	TRERF1	9	8	17	531.889
#230	PGBD1	9	14	23	480.713
#231	HOPX	9	14	23	1418.616
#232	SLC26A3	9	11	20	2439.517
#233	LMO4	9	10	19	1455.038
#234	SP140	9	10	19	982.832
#235	NR2F6	9	12	21	1229.886
#236	ANKRD30A	9	10	19	590.397
#237	ZNF449	9	11	20	2073.599
#238	ISL1	9	10	19	2112.983
#239	ZNF496	9	12	21	702.263
#240	PKNOX2	9	11	20	1834.314
#241	NFAT5	9	7	16	1196.668
#242	SPDEF	9	13	22	695.246
#243	EHF	9	15	24	1107.677
#244	DLX6	9	11	20	1879.159
#245	WNT5A	9	8	17	2089.231
#246	ZNF19	9	10	19	1141.353
#247	NFATC1	9	12	21	902.952
#248	KLF9	9	13	22	1059.311
#249	HOXB9	9	12	21	3849.673
#250	HEY2	9	11	20	1211.588
#251	KLF12	9	10	19	1981.153
#252	SIX2	9	11	20	569.773
#253	POU4F1	9	8	17	700.686
#254	HOXA9	9	11	20	848.714
#255	IRX5	9	13	22	772.016
#256	GSX2	9	8	17	678.832
#257	NEUROD2	9	12	21	917.664
#258	POU3F3	8	10	18	1250.018
#259	NPAS1	8	14	22	988.316
#260	FOXH1	8	10	18	671.097
#261	HOXD4	8	13	21	1314.064
#262	EN1	8	8	16	742.905
#263	MXD1	8	16	24	1830.964
#264	PDX1	8	14	22	1738.345
#265	LMX1A	8	14	22	2323.383
#266	RUNX3	8	7	15	180.007
#267	CUX2	8	10	18	1014.031
#268	PHTF1	8	8	16	1698.979
#269	TCF21	8	11	19	1149.124
#270	NFATC2	8	14	22	1044.134
#271	ATF7	8	10	18	1421.145
#272	BNC1	8	11	19	1666.243
#273	FOXC1	8	15	23	1743.009
#274	HOXC9	8	13	21	1214.201
#275	FOXR2	8	10	18	1225.131
#276	E2F2	8	7	15	834.205
#277	ZSCAN4	8	9	17	701.155
#278	IKZF3	8	7	15	581.391
#279	ZFHX2	8	12	20	859.437
#280	NR5A2	8	10	18	171.25
#281	BCL11B	8	12	20	1840.435
#282	ISL2	8	11	19	253.007
#283	ZNF132	8	15	23	1972.136
#284	ZNF238	8	15	23	2684.851
#285	T	8	9	17	618.261
#286	MITF	8	13	21	1665.731
#287	ETV4	8	12	20	896.55
#288	NKX2-1	8	6	14	814.882
#289	TP73	8	14	22	1573.024
#290	FOXO3	8	11	19	627.917
#291	ZIC3	8	6	14	770.85
#292	FOXL2	8	7	15	1106.932
#293	VAX2	8	11	19	1994.448
#294	ISX	8	13	21	1157.253
#295	GAS7	8	10	18	1039.565
#296	SMAD3	8	13	21	851.039
#297	OTX2	8	7	15	662.702
#298	PAX3	8	13	21	1645.288
#299	ZFP36L1	8	11	19	1332.153
#300	ZNF85	8	9	17	749.657
#301	RORB	8	8	16	1242.468
#302	FOXP1	8	12	20	2826.889
#303	PLSCR1	8	19	27	1688.587
#304	GSX1	8	10	18	1041.587
#305	KLF11	8	7	15	365.276
#306	RFX3	8	12	20	2688.388
#307	TSHZ3	7	13	20	1006.573
#308	MLLT10	7	8	15	354.498
#309	TEF	7	11	18	534.365
#310	POU2F3	7	11	18	865.563
#311	ZNF215	7	13	20	881.33
#312	NR2C1	7	13	20	411.42
#313	KCNH8	7	13	20	3394.935
#314	ZSCAN23	7	13	20	1762.418
#315	ZFPM2	7	13	20	1272.103
#316	CREM	7	14	21	461.997
#317	TRPS1	7	10	17	642.105
#318	TSHZ2	7	13	20	1344.526
#319	EGR2	7	12	19	1112.288
#320	KDM5B	7	12	19	1100.331
#321	MYT1L	7	14	21	2441.833
#322	POU6F2	7	11	18	831.783
#323	HOXD3	7	14	21	1237.984
#324	SOX1	7	9	16	747.978
#325	MESP2	7	9	16	771.563
#326	NANOGNB	7	15	22	2578.289
#327	GLIS3	7	13	20	1658.265
#328	TCF20	7	10	17	2911.136
#329	CEBPD	7	13	20	1610.114
#330	SOX18	7	13	20	2651.335
#331	HNF4G	7	12	19	343.802
#332	TBX20	7	9	16	1217.914
#333	ZNF41	7	9	16	1279.811
#334	TULP4	7	11	18	603.063
#335	REST	7	5	12	1451.869
#336	JUND	7	9	16	1144.662
#337	MEOX2	7	12	19	1159.232
#338	FOXP3	7	10	17	2024.232
#339	VSX1	7	11	18	847.926
#340	ZNF135	7	13	20	1599.802
#341	FOXO1	7	12	19	1118.602
#342	HMG20B	7	11	18	997.727
#343	NKX2-3	7	10	17	1663.47
#344	ZNF397	7	6	13	1039.478
#345	TSC22D2	7	12	19	1395.038
#346	BLZF1	7	10	17	630.981
#347	ZNF117	7	15	22	1149.765
#348	FOXD2	7	11	18	1396.77
#349	SATB2	7	12	19	1109.867
#350	ESRRB	7	11	18	1181.661
#351	NFKB2	7	12	19	720.139
#352	ERG	7	13	20	1503.633
#353	RARG	7	10	17	1587.143
#354	IRX4	7	11	18	754.479
#355	MYF5	7	8	15	1209.127
#356	MZF1	7	10	17	1494.609
#357	ZFP37	7	9	16	355.009
#358	ZSCAN20	7	8	15	2082.111
#359	ASCL1	7	10	17	248.546
#360	NR2E1	7	13	20	1207.267
#361	KLF17	6	12	18	1414.605
#362	TBX1	6	11	17	1141.877
#363	SMAD6	6	12	18	1771.975
#364	MEOX1	6	13	19	889.826
#365	GRHL2	6	13	19	722.051
#366	ARNT	6	12	18	1496.303
#367	ESR2	6	17	23	1709.392
#368	RCAN1	6	12	18	951.768
#369	NFIX	6	12	18	1249.787
#370	PITX2	6	15	21	755.005
#371	TFAP2B	6	12	18	894.034
#372	NR1I3	6	12	18	379.274
#373	SMAD4	6	9	15	800.13
#374	NR2E3	6	12	18	1041.359
#375	MAFB	6	12	18	257.644
#376	ZNF71	6	12	18	1582.728
#377	PGR	6	8	14	2802.252
#378	TFEC	6	13	19	464.219
#379	ETV2	6	13	19	791.301
#380	NR4A3	6	15	21	1953.322
#381	ZNF93	6	15	21	799.543
#382	SNAI2	6	10	16	793.637
#383	FLI1	6	15	21	411.214
#384	TRIM29	6	11	17	611.76
#385	ZNF90	6	10	16	773.882
#386	POU6F1	6	13	19	815.323
#387	CREBBP	6	11	17	1163.45
#388	TSC22D1	6	13	19	1267.935
#389	RARA	6	12	18	1750.512
#390	SIM1	6	18	24	1439.181
#391	GLI3	6	13	19	1536.702
#392	HSF5	6	11	17	1083.635
#393	SOX7	6	13	19	837.37
#394	HOXC13	6	12	18	764.94
#395	RXRG	6	10	16	864.408
#396	ZNF396	6	8	14	271.196
#397	TBX6	6	9	15	1033.854
#398	HAND1	6	11	17	1298.101
#399	ZNF75D	6	19	25	2021.569
#400	LHX6	6	6	12	642.307
#401	TWIST2	6	12	18	2434.085
#402	TBX22	6	13	19	2052.803
#403	DLX1	5	11	16	549.045
#404	FOXF1	5	12	17	549.347
#405	HNF1B	5	11	16	476.63
#406	NPAT	5	6	11	178.986
#407	GSC2	5	12	17	688.229
#408	RERE	5	15	20	2107.012
#409	BRD8	5	20	25	823.427
#410	NCOR1	5	11	16	731.833
#411	VDR	5	13	18	731.854
#412	ZNF207	5	15	20	1315.708
#413	PCGF2	5	13	18	572.677
#414	TLX3	5	13	18	1165.487
#415	ZKSCAN3	5	16	21	1964.301
#416	MGA	5	12	17	931.369
#417	ZNF157	5	13	18	863.839
#418	MYF6	5	15	20	1025.991
#419	POU4F3	5	13	18	937.25
#420	ALS2CR8	5	8	13	514.651
#421	ELK4	5	10	15	574.729
#422	PTH	5	10	15	791.279
#423	POU2F1	5	11	16	1126.784
#424	SIX3	5	11	16	704.013
#425	LZTS1	5	13	18	880.266
#426	POU1F1	5	9	14	702.306
#427	DLX4	5	9	14	633.444
#428	HNF4A	5	14	19	1941.981
#429	SOX5	5	11	16	1061.275
#430	SIN3A	5	15	20	782.387
#431	CDX2	5	6	11	96.21
#432	CREBZF	5	12	17	1392.757
#433	FOXD1	5	9	14	763.341
#434	NFIC	5	16	21	621.072
#435	NFIB	5	15	20	461.845
#436	REL	5	9	14	388.442
#437	ZNF175	5	10	15	507.142
#438	TFAP4	5	10	15	277.207
#439	ESX1	5	16	21	1126.891
#440	NFATC4	5	11	16	241.001
#441	EGR4	5	17	22	1690.744
#442	DMBX1	5	13	18	1722.962
#443	SOX11	5	13	18	1094.918
#444	ZHX3	5	8	13	643.033
#445	PHOX2B	5	11	16	707.565
#446	ETV5	5	10	15	113.2
#447	HCFC1	5	12	17	1132.226
#448	ZNF3	4	13	17	931.052
#449	ATOH1	4	15	19	724.709
#450	NKX6-2	4	9	13	572.112
#451	EPAS1	4	12	16	870.298
#452	DMRT2	4	15	19	1949.383
#453	ZNF81	4	8	12	166.491
#454	SNAPC5	4	10	14	518.303
#455	PRRX1	4	9	13	198.152
#456	ELF5	4	20	24	3804.755
#457	STRN3	4	14	18	652.881
#458	NFE2	4	12	16	698.644
#459	EN2	4	10	14	415.15
#460	C2orf3	4	13	17	523.207
#461	HNRNPAB	4	8	12	603.3
#462	PAX5	4	10	14	806.131
#463	POU3F2	4	16	20	900.094
#464	SPIC	4	12	16	496.119
#465	HOXD11	4	9	13	611.361
#466	PAX7	4	13	17	576.907
#467	HES6	4	15	19	284.558
#468	IRX2	4	7	11	152.995
#469	RUNX2	4	10	14	549.812
#470	OLIG2	4	9	13	944.122
#471	MTA2	4	14	18	455.328
#472	TFDP3	4	10	14	559.009
#473	NFYA	4	10	14	613.755
#474	PPBPL2	4	18	22	1571.679
#475	PEG3	4	10	14	289.72
#476	ZXDC	4	13	17	468.256
#477	ZFP42	4	12	16	674.912
#478	RUNX1T1	4	10	14	494.038
#479	GBX2	3	12	15	318.791
#480	SP4	3	12	15	523.562
#481	GATAD1	3	14	17	1036.227
#482	PAX8	3	15	18	439.595
#483	ZNF434	3	9	12	575.179
#484	GRHL3	3	9	12	358.41
#485	TCF12	3	13	16	236.812
#486	POU3F4	3	12	15	2504.51
#487	RUNX1	3	15	18	1116.974
#488	TFE3	3	16	19	1083.598
#489	HOXB8	3	12	15	423.925
#490	GATA3	3	17	20	619.285
#491	AFF4	3	14	17	713.011
#492	HOXC12	2	5	7	532.843
#493	RELA	2	15	17	928.854
#494	ZFHX4	2	15	17	1653.372
#495	FOXS1	2	8	10	143.25
#496	C12orf28	2	8	10	118.822
#497	HIF3A	2	10	12	211.466
#498	FOXE1	1	16	17	72.918
#499	HOXD13	1	12	13	378.517
#500	MYCL1	1	10	11	145.688