Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZFP36L2	33	7	40	3774.176
#2	KLF6	33	3	36	863.732
#3	ENO1	33	1	34	34.738
#4	ATF6	29	1	30	25.804
#5	ELF3	27	5	32	295.828
#6	ZNF91	25	2	27	564.8
#7	STAT1	25	9	34	604.964
#8	ZNF281	25	4	29	1044.984
#9	HMBOX1	24	5	29	2222.207
#10	GTF2I	24	2	26	1198.75
#11	MSRB2	23	3	26	617.454
#12	JUNB	23	3	26	405.513
#13	SOX9	22	9	31	965.262
#14	BCL3	22	8	30	311.767
#15	MSX1	22	8	30	268.315
#16	HEYL	21	10	31	8076.636
#17	ZNF117	21	6	27	298.322
#18	JUND	21	7	28	257.409
#19	EGR4	20	1	21	77.031
#20	CDX2	20	5	25	665.499
#21	SREBF1	20	6	26	4893.41
#22	NFAT5	19	6	25	19779.222
#23	MAX	19	7	26	3988.837
#24	FEV	19	9	28	2269.094
#25	HSF1	18	8	26	733.44
#26	SOX18	18	10	28	2562.305
#27	STAT6	18	10	28	764.522
#28	MSL3	18	8	26	1445.797
#29	SP1	18	4	22	634.639
#30	MYBL2	18	7	25	270.606
#31	ZFHX4	17	6	23	1063.662
#32	TFAP2A	17	14	31	4952.233
#33	RBPJ	17	1	18	53.994
#34	TADA3	17	7	24	1620.227
#35	TCF7L2	17	10	27	1885.378
#36	REL	17	9	26	852.36
#37	FOXO3	17	8	25	773.425
#38	ZSCAN18	17	6	23	1470.547
#39	NKX3-2	17	8	25	903.267
#40	MLXIPL	16	11	27	1628.884
#41	TFAP4	16	17	33	3336.68
#42	TCF12	16	7	23	1197.164
#43	SNAI2	16	7	23	469.307
#44	ZNF236	16	6	22	1007.588
#45	SMAD3	16	6	22	632.093
#46	SATB2	16	10	26	362.863
#47	DLX4	16	9	25	1887.725
#48	RORA	16	7	23	807.119
#49	MYCL1	16	8	24	1529.09
#50	ZNF131	15	7	22	352.112
#51	GTF2H4	15	9	24	538.422
#52	MYF5	15	7	22	1301.594
#53	PROX1	15	7	22	1157.394
#54	HSF2	15	7	22	327.227
#55	TP73	15	11	26	1231.295
#56	TSC22D4	15	5	20	624.735
#57	BTG2	15	6	21	174.437
#58	SNAPC2	15	10	25	1295.228
#59	CREBZF	15	11	26	1822.2
#60	ZKSCAN1	15	5	20	542.674
#61	RUNX1T1	15	13	28	1340.36
#62	FOXN1	14	10	24	2718.467
#63	TFEB	14	11	25	1244.892
#64	TP53	14	6	20	14644.306
#65	SALL2	14	12	26	1127.985
#66	ZNF444	14	5	19	548.408
#67	FOXN2	14	6	20	191.459
#68	ZNF41	14	9	23	921.518
#69	MSC	14	9	23	2083.104
#70	JUN	14	3	17	315.003
#71	LEF1	14	11	25	2712.061
#72	SNAPC5	14	10	24	1168.523
#73	RARB	13	12	25	1623.562
#74	PHF1	13	10	23	1215.868
#75	FOXN3	13	6	19	991.772
#76	ONECUT2	13	7	20	1446.494
#77	ZNF174	13	9	22	964.923
#78	LHX2	13	9	22	1011.744
#79	MYT1L	13	11	24	1946.44
#80	TAF4	13	6	19	1043.599
#81	FOXF2	13	12	25	2633.817
#82	AHR	13	8	21	973.897
#83	ZNF192	13	11	24	666.857
#84	RXRG	13	9	22	1629.673
#85	NR1I2	13	9	22	1310.291
#86	NR2E1	13	13	26	1922.177
#87	NOLC1	13	6	19	1057.161
#88	TSC22D3	13	9	22	884.821
#89	HOXD4	13	12	25	1432.874
#90	KLF7	13	5	18	208.602
#91	TADA2A	13	12	25	1663.323
#92	ARNTL2	13	9	22	2631.624
#93	NR6A1	13	3	16	462.119
#94	ELK3	13	10	23	2304.342
#95	E2F4	13	8	21	1226.903
#96	DMRT1	13	9	22	1528.628
#97	CLOCK	13	8	21	1761.037
#98	PBX2	13	7	20	1038.61
#99	HMX1	13	6	19	897.956
#100	SOX1	13	8	21	1161.113
#101	PPBPL2	13	9	22	1190.387
#102	STRN3	13	6	19	349.416
#103	SP4	13	9	22	932.653
#104	RB1	12	9	21	20509.494
#105	SIX6	12	13	25	2168.818
#106	ARNT	12	13	25	20305.879
#107	CSRNP3	12	8	20	732.921
#108	HOXB1	12	12	24	2019.201
#109	FOSB	12	8	20	306.665
#110	ZNF3	12	12	24	1307.596
#111	EGR2	12	6	18	214.387
#112	HOXD12	12	8	20	1254.486
#113	ZNF197	12	7	19	1536.828
#114	ZKSCAN3	12	9	21	20314.021
#115	HOXB13	12	11	23	5583.88
#116	SMAD5	12	9	21	2514.693
#117	SMAD1	12	3	15	178.82
#118	STAT5A	12	8	20	996.437
#119	HSF4	12	13	25	1666.931
#120	TBX1	12	10	22	1051.404
#121	SPI1	12	9	21	1139.504
#122	PRRX1	12	6	18	642.565
#123	EN2	12	4	16	828.374
#124	USF2	12	12	24	2012.343
#125	ZNF446	12	8	20	1166.972
#126	RORB	12	14	26	1956.736
#127	RFX3	12	8	20	862.131
#128	NR5A2	12	10	22	1573.75
#129	TSHZ2	12	12	24	1638.951
#130	ETS2	12	6	18	451.926
#131	TLX1	12	6	18	1400.771
#132	BACH1	12	6	18	957.744
#133	NPAS2	12	7	19	1217.702
#134	POU2F2	12	10	22	1286.016
#135	BHLHE40	12	7	19	372.599
#136	EPAS1	12	7	19	785.623
#137	ST18	12	16	28	1906.79
#138	CITED1	12	10	22	871.106
#139	HOXB2	12	10	22	1042.391
#140	BRD8	12	10	22	1667.633
#141	NR4A2	12	8	20	404.36
#142	TBX10	12	14	26	1785.595
#143	MZF1	12	8	20	777.415
#144	TFCP2L1	12	11	23	946.972
#145	ETV6	11	7	18	538.462
#146	LMX1B	11	12	23	1970.212
#147	SP140	11	9	20	1360.742
#148	HOXD9	11	11	22	1897.134
#149	GBX1	11	10	21	1258.671
#150	IRX4	11	9	20	771.735
#151	FLI1	11	15	26	1938.498
#152	VDR	11	10	21	1363.858
#153	SOX5	11	10	21	1308.092
#154	RFXAP	11	11	22	21768.17
#155	HIF3A	11	10	21	1632.806
#156	SPDEF	11	6	17	1393.161
#157	CREB3L1	11	11	22	1448.552
#158	KLF10	11	2	13	91.487
#159	FOSL2	11	9	20	1001.567
#160	TCF3	11	10	21	2557.032
#161	LHX6	11	11	22	1890.966
#162	LHX3	11	8	19	801.858
#163	ZNF81	11	7	18	1342.08
#164	MLLT10	11	8	19	1346.155
#165	ALX3	11	10	21	1501.194
#166	POU3F2	11	8	19	1266.454
#167	MYC	11	4	15	150.432
#168	HOXA6	11	10	21	1193.127
#169	MAFF	11	2	13	52.936
#170	HOXA3	11	10	21	674.458
#171	NR4A1	11	1	12	36.394
#172	NFX1	11	8	19	306.779
#173	RBPJL	11	9	20	1500.941
#174	ASCL2	11	12	23	528.988
#175	MYOD1	11	8	19	1488.506
#176	ETV4	11	13	24	2970.101
#177	HLF	11	14	25	1498.267
#178	TBR1	11	8	19	578.417
#179	CREM	11	12	23	1569.388
#180	RFX1	11	6	17	1233.126
#181	HNF4G	11	8	19	1127.103
#182	KLF15	10	8	18	1972.993
#183	POU1F1	10	12	22	1401.534
#184	PLAG1	10	11	21	1450.287
#185	EGR3	10	5	15	152.714
#186	TRIM22	10	11	21	1256.837
#187	HOXD3	10	9	19	1191.574
#188	EGR1	10	7	17	168.57
#189	FOXL2	10	7	17	962.037
#190	SIM2	10	6	16	171.259
#191	KLF1	10	9	19	1187.928
#192	RUNX3	10	9	19	1191.315
#193	SIX3	10	11	21	1090.073
#194	MYF6	10	9	19	1292.823
#195	TCF21	10	11	21	1571.493
#196	PKNOX1	10	12	22	1993.041
#197	NR1I3	10	10	20	1662.672
#198	SOX21	10	14	24	1651.144
#199	PHOX2A	10	7	17	1003.951
#200	ZHX3	10	12	22	1307.645
#201	CBL	10	7	17	715.177
#202	NFIB	10	9	19	530.695
#203	RARA	10	13	23	1420.416
#204	STAT2	10	9	19	1864.649
#205	VENTX	10	9	19	1214.869
#206	HR	10	10	20	530.186
#207	DLX2	10	6	16	291.189
#208	HMGA2	10	12	22	1456.456
#209	MEF2D	10	9	19	1464.685
#210	NKX2-8	10	11	21	1451.851
#211	NKX6-1	10	11	21	1372.753
#212	MYOG	10	10	20	1091.772
#213	HOXC8	10	11	21	1730.482
#214	FOXP3	10	10	20	1069.206
#215	NR2C1	10	8	18	909.633
#216	TCF15	10	14	24	1555.305
#217	HOPX	10	9	19	526.361
#218	NFATC4	10	9	19	705.654
#219	MAFK	10	9	19	760.084
#220	GBX2	10	5	15	943.652
#221	FOXE3	10	9	19	1096.19
#222	BUD31	10	9	19	764.097
#223	HAND1	10	6	16	657.662
#224	ELK4	10	10	20	916.102
#225	BCL6	10	8	18	185.39
#226	TFDP1	10	9	19	577.927
#227	ETV7	10	7	17	1129.641
#228	AFF4	10	7	17	733.56
#229	ESRRB	10	5	15	709.523
#230	HCFC1	9	6	15	564.265
#231	SCRT1	9	6	15	1092.675
#232	ZNF202	9	11	20	928.021
#233	ZNF287	9	13	22	1250.699
#234	SMAD9	9	8	17	1042.02
#235	SLC26A3	9	13	22	2028.358
#236	POU3F1	9	11	20	1266.068
#237	PPARA	9	8	17	996.355
#238	VTN	9	8	17	1259.191
#239	LMO4	9	10	19	1157.638
#240	LHX5	9	5	14	574.154
#241	SRF	9	8	17	617.107
#242	ZNF154	9	7	16	707.895
#243	IKZF4	9	9	18	1393.775
#244	ZEB1	9	10	19	1299.697
#245	BLZF1	9	10	19	690.658
#246	NR2E3	9	7	16	506.69
#247	SHOX	9	11	20	1183.477
#248	SOX4	9	6	15	138.095
#249	HOXA7	9	16	25	1515.402
#250	TFDP3	9	8	17	814.849
#251	YY1	9	12	21	1237.055
#252	T	9	15	24	2158.788
#253	ZSCAN2	9	15	24	1651.307
#254	FOXD1	9	11	20	1249.717
#255	MEOX2	9	13	22	1820.134
#256	FOXJ1	9	15	24	1591.54
#257	TBX21	9	11	20	1180.4
#258	TRIM29	9	8	17	561.329
#259	PEG3	9	13	22	2004.611
#260	NR2F1	9	10	19	1255.802
#261	GTF2H3	9	4	13	78.735
#262	HMGA1	9	5	14	383.299
#263	KLF2	9	10	19	312.447
#264	HNF4A	9	12	21	720.207
#265	ESR1	9	11	20	1146.313
#266	NANOG	9	11	20	1394.857
#267	DLX6	9	8	17	1461.828
#268	TEF	9	14	23	1536.218
#269	TAF4B	9	6	15	559.112
#270	HOXB8	8	15	23	1863.19
#271	NFE2	8	9	17	893.29
#272	ZNF434	8	8	16	798.546
#273	ZNF135	8	12	20	992.736
#274	FOXA2	8	12	20	1287.758
#275	NR4A3	8	8	16	478.131
#276	FOXD3	8	9	17	732.591
#277	NRL	8	13	21	1178.384
#278	CDKN2A	8	14	22	1744.126
#279	RUNX2	8	11	19	1285.173
#280	HAND2	8	7	15	911.203
#281	WT1	8	10	18	945.632
#282	OVOL1	8	7	15	1088.613
#283	POU6F1	8	10	18	1203.062
#284	SATB1	8	9	17	1142.333
#285	HOXA4	8	14	22	1422.593
#286	FOXO4	8	9	17	1508
#287	ETV5	8	9	17	948.526
#288	TLX2	8	12	20	878.965
#289	ATF7	8	4	12	300.289
#290	REST	8	10	18	928.328
#291	MMP14	8	14	22	1083.474
#292	TCF25	8	13	21	1608.104
#293	MYCN	8	8	16	985.605
#294	PITX1	8	11	19	1048.356
#295	RCAN1	8	7	15	793.923
#296	TFCP2	8	16	24	1928.262
#297	RELB	8	8	16	777.878
#298	HCLS1	8	11	19	1109.687
#299	ESRRA	8	12	20	995.026
#300	KDM5B	8	12	20	1247.016
#301	BHLHE41	8	9	17	432.91
#302	NEUROG1	8	7	15	847.117
#303	POU3F3	8	11	19	888.501
#304	TBX6	8	10	18	546.349
#305	PRDM1	8	9	17	997.587
#306	KLF9	8	12	20	1204.443
#307	ASCL1	8	12	20	2298.917
#308	PAX8	8	11	19	1634.528
#309	DDIT3	8	3	11	155.319
#310	CRX	8	9	17	912.186
#311	CREB5	8	12	20	1072.976
#312	MBD1	8	12	20	1392.05
#313	FOXH1	8	10	18	1271.435
#314	POU6F2	8	10	18	1421.721
#315	HOXB3	8	8	16	734.792
#316	ZEB2	8	11	19	871.964
#317	NEUROD1	8	10	18	946.419
#318	ONECUT1	8	11	19	312.144
#319	SCAND2	8	12	20	1368.41
#320	HOXA11	8	13	21	1224.906
#321	POU2F3	8	7	15	702.898
#322	RORC	8	10	18	703.188
#323	FOXL1	8	9	17	731.199
#324	MAFG	8	6	14	142.273
#325	FOXJ3	8	12	20	1135.027
#326	ELF5	8	12	20	741.785
#327	PITX3	8	8	16	1109.791
#328	BNC1	8	9	17	969.57
#329	NFATC1	7	9	16	709.41
#330	MTA2	7	9	16	753.33
#331	FOXG1	7	12	19	1741.005
#332	FUBP1	7	16	23	1218.058
#333	ETV3	7	8	15	1211.796
#334	POU4F3	7	7	14	939.972
#335	RERE	7	14	21	1255.625
#336	ETV2	7	13	20	713.491
#337	GCM1	7	11	18	699.446
#338	ZNF132	7	13	20	1258.956
#339	MYT1	7	13	20	1388.855
#340	SPIB	7	13	20	11638.246
#341	ZBTB17	7	10	17	575.683
#342	ETS1	7	13	20	899.341
#343	MEOX1	7	10	17	643.348
#344	TBX4	7	10	17	818.852
#345	ATF5	7	12	19	932.063
#346	HMG20B	7	9	16	830.701
#347	ZNF175	7	9	16	569.031
#348	SIX2	7	5	12	211.36
#349	POU5F1B	7	9	16	932.42
#350	STAT4	7	9	16	1115.001
#351	AEBP1	7	9	16	686.334
#352	EN1	7	11	18	648.85
#353	SIX1	7	13	20	1380.044
#354	HIC1	7	11	18	817.047
#355	SIM1	7	12	19	1244.136
#356	BCL11B	7	11	18	790.707
#357	HOXD10	7	11	18	1050.877
#358	NKX3-1	7	11	18	875.519
#359	CEBPD	7	7	14	676.156
#360	MSX2	7	11	18	1358.584
#361	CUX2	7	17	24	1392.836
#362	PDX1	7	10	17	1170.19
#363	ZFP36L1	7	14	21	892.522
#364	SOX15	7	12	19	1091.715
#365	PRRX2	7	12	19	993.06
#366	TEAD4	7	11	18	856.966
#367	LHX1	7	9	16	265.614
#368	HOXB9	7	7	14	524.089
#369	ATF3	7	3	10	161.65
#370	SOX11	7	11	18	903.216
#371	TBX2	7	12	19	696.234
#372	HNF1A	7	10	17	1054.866
#373	NPAS1	7	12	19	2138.749
#374	NFIX	7	16	23	1117.199
#375	HES1	7	12	19	926.81
#376	GATA4	7	13	20	1237.618
#377	TBX5	7	7	14	756.578
#378	HOXA2	6	14	20	2288.328
#379	TFEC	6	13	19	994.287
#380	ZNF80	6	11	17	852.444
#381	VSX1	6	11	17	726.059
#382	ATOH1	6	9	15	948.884
#383	SALL1	6	13	19	754.96
#384	EVX1	6	13	19	647.933
#385	HOXA1	6	7	13	527.695
#386	OLIG2	6	10	16	989.495
#387	E2F2	6	10	16	473.591
#388	POU4F2	6	12	18	945.021
#389	NR3C2	6	10	16	909.448
#390	SRY	6	9	15	841.821
#391	GLI2	6	17	23	1575.186
#392	NFKB2	6	16	22	1095.937
#393	ZFP37	6	12	18	1133.61
#394	PHOX2B	6	12	18	1219.605
#395	PAX4	6	11	17	771.505
#396	ZNF215	6	11	17	1115.339
#397	FOS	6	7	13	305.258
#398	WNT5A	6	10	16	669.732
#399	MLL	6	11	17	286.983
#400	NEUROD2	6	11	17	860.688
#401	ESR2	6	9	15	613.829
#402	DBP	6	12	18	730.904
#403	PAX5	6	10	16	584.728
#404	CBFA2T2	6	14	20	1321.349
#405	CEBPE	6	9	15	827.655
#406	RXRB	6	7	13	571.375
#407	EHF	6	13	19	2192.876
#408	SMAD6	6	8	14	652.374
#409	FOSL1	6	4	10	63.046
#410	AFF1	6	13	19	880.416
#411	ETV1	6	9	15	955.875
#412	BARX1	6	12	18	957.587
#413	NR5A1	6	13	19	938.869
#414	EMX1	6	12	18	858.34
#415	IRF5	6	12	18	742.113
#416	CSDA	6	6	12	740.593
#417	TSC22D2	6	10	16	735.885
#418	IKZF1	6	11	17	1044.084
#419	NKX2-1	6	11	17	972.234
#420	HOXD11	6	13	19	793.929
#421	FOXD2	6	12	18	888.086
#422	TLX3	6	12	18	1099.281
#423	PAX7	6	14	20	1672.193
#424	ERG	6	15	21	1154.427
#425	MEF2C	5	8	13	456.302
#426	TAF13	5	7	12	300.755
#427	RUNX1	5	16	21	841.815
#428	TAL1	5	13	18	622.281
#429	FOXC2	5	12	17	1049.804
#430	KLF12	5	16	21	1003.235
#431	HOXA9	5	12	17	1489.188
#432	FOXO1	5	8	13	345.109
#433	ZNF238	5	11	16	769.808
#434	IRF4	5	16	21	998.791
#435	FOXE1	5	16	21	1133.671
#436	ZNF167	5	11	16	562.511
#437	PRDM2	5	15	20	899.572
#438	ZFPM2	5	13	18	1022.316
#439	ZSCAN12	5	9	14	775.494
#440	HOXC5	5	9	14	865.884
#441	ATF6B	5	15	20	974.597
#442	GATA1	5	10	15	675.735
#443	PTH	5	11	16	763.209
#444	BATF3	5	11	16	2054.653
#445	THRB	5	6	11	262.716
#446	NKX2-5	5	11	16	716.104
#447	PPARD	5	9	14	699.104
#448	IKZF3	5	16	21	755.187
#449	HEY1	5	11	16	650.09
#450	TCF7	5	15	20	976.938
#451	NR2F6	5	11	16	145.272
#452	SOX2	5	13	18	744.74
#453	PURA	5	7	12	296.296
#454	POU4F1	5	13	18	821.197
#455	SOX17	5	13	18	726.792
#456	RARG	5	11	16	959.715
#457	ESRRG	5	15	20	1177.924
#458	ALX4	5	8	13	430.096
#459	FOXF1	5	8	13	403.626
#460	FOXB1	5	10	15	937.792
#461	THRA	4	10	14	405.412
#462	FOXI1	4	11	15	748.676
#463	HOXB5	4	7	11	375.365
#464	BACH2	4	10	14	348.825
#465	HOXD1	4	10	14	468.881
#466	IRF8	4	12	16	748.496
#467	NR0B1	4	13	17	968.904
#468	HOXD13	4	10	14	448.176
#469	NR1H4	4	15	19	535.583
#470	CREBBP	4	13	17	653.368
#471	ZIC3	4	14	18	499.431
#472	MAF	4	14	18	601.513
#473	HNF1B	4	11	15	711.3
#474	GAS7	4	12	16	464.04
#475	TCF4	4	14	18	770.181
#476	POU3F4	4	12	16	758.318
#477	SIX5	4	7	11	281.158
#478	SOX30	4	18	22	853.52
#479	VAV1	4	15	19	692.716
#480	PKNOX2	4	11	15	759.118
#481	HOXB6	4	11	15	554.483
#482	TWIST1	4	12	16	724.457
#483	ZNF639	4	8	12	294.147
#484	TFAP2B	4	12	16	766.953
#485	ALX1	3	9	12	368.95
#486	TP63	3	15	18	438.27
#487	NFIC	3	14	17	333.393
#488	PAX6	3	14	17	388.147
#489	MXD1	3	15	18	572.284
#490	HESX1	3	10	13	329.133
#491	C11orf9	3	12	15	733.96
#492	NPAT	3	13	16	432.999
#493	LZTS1	3	17	20	1025.153
#494	MECOM	3	12	15	638.949
#495	ELK1	3	13	16	274.464
#496	PAX3	3	11	14	409.533
#497	SOX10	2	9	11	109.156
#498	ZNF157	2	19	21	570.352
#499	GSC2	2	10	12	337.085
#500	ISL1	2	12	14	495.747