Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	WT1	53	4	57	5009.368
#2	SOX17	48	2	50	380.867
#3	HNF1B	47	2	49	322.08
#4	ADNP	40	3	43	177.538
#5	NFYC	39	6	45	1269.074
#6	MEIS1	37	5	42	243.369
#7	KLF2	36	7	43	2142.126
#8	TCF4	36	8	44	862.119
#9	TGIF2	35	1	36	138.507
#10	FOXN3	34	10	44	1032.069
#11	STAT5B	34	6	40	795.9
#12	MYCL1	34	19	53	6011.706
#13	GTF2I	32	7	39	695.251
#14	PBX3	32	6	38	932.294
#15	ZFPM2	31	5	36	978.588
#16	NFATC3	31	12	43	1882.657
#17	ESR1	31	3	34	555.861
#18	SALL2	31	11	42	1709.074
#19	FOXO1	30	7	37	1336.168
#20	TCF21	30	4	34	937.191
#21	ZNF217	30	7	37	1266.585
#22	TCF25	30	7	37	1392.448
#23	MEF2C	29	7	36	954.279
#24	FOXM1	29	6	35	633.227
#25	MITF	29	6	35	483.43
#26	GRHL2	29	8	37	479.103
#27	JUNB	29	2	31	157.472
#28	PBX1	29	6	35	1621.284
#29	MNX1	28	7	35	1332.461
#30	PTTG1	28	2	30	268.166
#31	MECOM	28	10	38	6902.512
#32	GABPA	28	11	39	1325.75
#33	NR1H4	28	8	36	1365.392
#34	FOXL2	27	3	30	484.538
#35	TCF7L1	27	6	33	382.007
#36	IRF6	27	10	37	2260.185
#37	ATF6	27	6	33	735.885
#38	SPEN	27	7	34	470.835
#39	CREB1	27	10	37	1730.204
#40	GTF2H3	27	6	33	544.532
#41	E2F5	26	12	38	993.43
#42	TCEAL1	26	7	33	1238.104
#43	FOXA2	26	5	31	183.084
#44	GATAD2A	25	9	34	1933.742
#45	PEG3	25	5	30	693.642
#46	MAX	25	10	35	1699.967
#47	EPAS1	25	9	34	973.812
#48	ARID3A	25	11	36	5339.95
#49	ZBTB38	25	5	30	1444.935
#50	NR1I2	25	9	34	1378.966
#51	YBX1	25	5	30	652.487
#52	NFYB	25	8	33	689.676
#53	IRF1	24	7	31	2864.596
#54	KLF5	24	10	34	1286.045
#55	MSX2	24	6	30	2015.805
#56	BHLHE41	24	9	33	1305.798
#57	ELF3	24	13	37	3521.944
#58	MAFG	24	9	33	3537.343
#59	PAX8	23	8	31	783.309
#60	PLSCR1	23	6	29	599.574
#61	SALL1	23	4	27	699.184
#62	TCF7	23	6	29	581.993
#63	BCL3	23	9	32	4170.034
#64	E2F3	23	12	35	2342.733
#65	ZNF193	22	6	28	1026.119
#66	SMAD5	22	8	30	845.737
#67	CREBL2	22	10	32	724.671
#68	AFF1	21	9	30	2373.366
#69	KLF11	21	11	32	2497.429
#70	PPARG	21	10	31	732.949
#71	ZEB1	21	9	30	2021.406
#72	TFDP2	21	12	33	1088.735
#73	STAT3	20	13	33	2051.394
#74	HMGA1	20	17	37	1955.391
#75	TFCP2L1	20	11	31	1325.693
#76	MAFF	20	8	28	368.873
#77	SMAD4	20	8	28	717.593
#78	C2orf3	20	8	28	540.262
#79	E2F6	20	13	33	2138.948
#80	NFIB	20	15	35	1759.736
#81	IRF7	20	10	30	2329.523
#82	KLF4	20	8	28	958.604
#83	PBX2	20	11	31	1214.612
#84	CEBPB	19	12	31	963.52
#85	TFAP2C	19	11	30	1152.958
#86	PPARD	19	18	37	2704.051
#87	LEF1	19	16	35	2578.018
#88	SCML1	19	9	28	816.983
#89	CREB3L1	19	10	29	761.632
#90	STAT1	19	7	26	1213.74
#91	CITED2	19	16	35	2909.807
#92	ZNF131	19	11	30	979.951
#93	SNAI2	19	4	23	787.181
#94	SUPT4H1	19	15	34	2163.542
#95	ZNF3	18	13	31	1470.078
#96	KDM5A	18	10	28	655.335
#97	NR4A1	18	3	21	117.928
#98	BHLHE40	18	9	27	1263.086
#99	TFEC	18	12	30	2033.746
#100	SMAD3	18	13	31	1211.216
#101	KDM5B	18	13	31	1525.197
#102	SLC2A4RG	17	5	22	216.439
#103	ZHX3	17	14	31	1023.316
#104	RARG	17	9	26	683.877
#105	GATA4	17	9	26	224.259
#106	TRIM22	17	16	33	2170.7
#107	NR3C1	17	12	29	1355.755
#108	HDAC1	17	11	28	1700.026
#109	TAF12	17	9	26	1195.069
#110	FOXA1	17	16	33	2644.769
#111	SPDEF	17	14	31	1402.153
#112	FOSL2	17	13	30	1369.757
#113	TSC22D1	17	16	33	1891.97
#114	RELA	17	10	27	1504.661
#115	IRX5	17	10	27	2854.393
#116	ENO1	17	11	28	1395.334
#117	IRF8	17	12	29	711.033
#118	RB1	17	9	26	967.858
#119	SOX4	17	10	27	702.438
#120	STRN3	16	15	31	2802.55
#121	RUNX1T1	16	11	27	2920.062
#122	HOXD3	16	6	22	417.904
#123	ZNF148	16	7	23	543.429
#124	FUBP1	16	7	23	1427.791
#125	TWIST1	16	9	25	1492.559
#126	CNOT8	16	11	27	844.805
#127	E4F1	16	11	27	2509.841
#128	TSC22D3	16	7	23	517.18
#129	CDKN2A	16	17	33	2365.468
#130	ZNF93	16	11	27	1817.911
#131	HOXD1	16	11	27	888.597
#132	SP1	15	9	24	421.818
#133	HIRA	15	12	27	1131.945
#134	FOS	15	2	17	179.212
#135	TLX3	15	12	27	2711.138
#136	EGR3	15	7	22	219.413
#137	MSX1	15	13	28	727.594
#138	NR0B1	15	10	25	2245.279
#139	PLAGL2	15	11	26	1033.904
#140	ZSCAN16	15	12	27	1092.361
#141	TCF3	15	16	31	1668.607
#142	PGR	15	11	26	445.909
#143	NR3C2	15	9	24	1018.141
#144	MLX	15	11	26	1146.403
#145	HCLS1	15	15	30	1315.095
#146	BTG2	15	10	25	417.013
#147	EGR1	15	2	17	1058.586
#148	TFAM	15	7	22	517.668
#149	MAF	14	8	22	782.23
#150	PKNOX2	14	16	30	1573.251
#151	SCML2	14	6	20	537.251
#152	REL	14	12	26	2316.447
#153	BCL6	14	7	21	186.14
#154	NPAS2	14	13	27	1265.929
#155	HMGA2	14	10	24	667.299
#156	RUNX1	14	14	28	1583.971
#157	AEBP1	14	11	25	755.032
#158	POU6F1	14	17	31	2839.545
#159	KLF9	14	10	24	1284.65
#160	ZXDC	14	15	29	1531.029
#161	IRF9	14	8	22	891.478
#162	DBP	14	15	29	1796.824
#163	GATA6	14	16	30	2189.476
#164	RFXANK	14	14	28	1878.19
#165	TRIM25	14	12	26	1847.948
#166	E2F1	14	9	23	629.113
#167	ZBTB48	14	13	27	816.956
#168	CEBPA	14	8	22	1430.162
#169	HMBOX1	13	12	25	1814.227
#170	MXD1	13	11	24	1420.526
#171	ETV1	13	19	32	1708.82
#172	PHOX2A	13	14	27	2259.465
#173	MYCN	13	16	29	835.113
#174	PRRX2	13	14	27	1368.724
#175	HEY1	13	12	25	989.162
#176	ERG	13	10	23	1138.004
#177	YY1	13	12	25	1182.071
#178	HES1	13	12	25	1016.683
#179	EHF	13	17	30	690.516
#180	ZNF83	13	14	27	2448.189
#181	EN2	13	13	26	1706.738
#182	FOSB	13	4	17	247.62
#183	TRIM29	13	14	27	1527.76
#184	HOXA10	13	12	25	2025.551
#185	ZGPAT	13	16	29	1712.131
#186	ZNF134	13	13	26	1394.867
#187	VDR	13	17	30	1518.644
#188	NFIC	12	15	27	1555.358
#189	E2F8	12	11	23	1536.926
#190	BATF3	12	11	23	3085.848
#191	AHR	12	11	23	602.642
#192	FOXO3	12	10	22	604.112
#193	BATF	12	13	25	694.618
#194	ZFP36L1	12	19	31	2070.466
#195	ZFP36L2	12	15	27	2294.813
#196	NR1D2	12	10	22	1168.216
#197	VAV1	12	12	24	1931.324
#198	ZNF238	12	17	29	6154.304
#199	SOX9	12	16	28	1307.615
#200	MYC	11	19	30	1696.19
#201	T	11	9	20	2019.465
#202	JUND	11	11	22	2077.079
#203	NR2F1	11	15	26	970.305
#204	ATF3	11	6	17	1879.401
#205	NR2E3	11	10	21	1112.471
#206	HOXB7	11	9	20	1653.913
#207	SATB2	11	18	29	2668.024
#208	PITX1	11	15	26	1880.852
#209	TRPS1	11	13	24	799.681
#210	KLF6	11	14	25	1220.289
#211	ELF1	11	14	25	576.224
#212	PPBPL2	11	15	26	1351.888
#213	PITX2	11	11	22	1673.149
#214	TAF1B	11	13	24	1763.008
#215	HSF1	11	11	22	2234.229
#216	RFX5	11	13	24	603.415
#217	NFIL3	11	10	21	584.237
#218	RBCK1	11	11	22	532.936
#219	ZNF232	11	12	23	1077.947
#220	ZKSCAN1	11	15	26	1640.214
#221	ZNF167	11	13	24	2896.455
#222	THRA	11	14	25	1215.263
#223	ZNF75D	11	15	26	1750.177
#224	DDIT3	11	12	23	915.392
#225	SUPT6H	11	17	28	1934.222
#226	MZF1	11	19	30	2441.149
#227	GLI2	11	13	24	1707.952
#228	FOXG1	11	11	22	1153.302
#229	HOXC10	11	13	24	1356.298
#230	TCF7L2	11	16	27	1484.599
#231	CEBPD	10	18	28	1448.914
#232	TFDP1	10	19	29	1162.526
#233	ATOH1	10	12	22	2197.015
#234	FLI1	10	12	22	882.45
#235	HLF	10	12	22	1957.477
#236	SATB1	10	19	29	2522.77
#237	RXRB	10	15	25	1118.906
#238	CREM	10	12	22	1572.274
#239	ASCL1	10	9	19	2119.218
#240	LASS2	10	8	18	394.75
#241	SMAD6	10	13	23	2215.324
#242	EGR2	10	8	18	570.335
#243	SIX3	10	13	23	1329.464
#244	HOXA2	10	8	18	1293.027
#245	NFKB2	10	14	24	1718.365
#246	NPAT	10	12	22	633.705
#247	TFAP2A	10	21	31	1875.397
#248	ERF	10	11	21	864.119
#249	HDAC2	10	15	25	1452.797
#250	XBP1	10	10	20	551.15
#251	HMG20B	10	12	22	487.214
#252	ETV4	10	13	23	2247.505
#253	FOSL1	10	9	19	1364.379
#254	TFE3	10	13	23	1945.397
#255	TEAD4	10	12	22	2196.075
#256	TCFL5	10	15	25	862.216
#257	LASS6	10	14	24	772.276
#258	SPI1	10	9	19	1388.661
#259	POU5F1B	10	15	25	1532.895
#260	CNOT7	10	14	24	963.485
#261	MAFB	9	21	30	3225.789
#262	DLX6	9	15	24	3127.852
#263	NR1H3	9	12	21	779.102
#264	WNT5A	9	17	26	1402.795
#265	PLAG1	9	12	21	1497.507
#266	SOX11	9	9	18	1200.496
#267	ELK4	9	8	17	222.097
#268	CRX	9	14	23	2378.66
#269	TLX1	9	20	29	2248.131
#270	NR5A2	9	11	20	1601.981
#271	PTH	9	9	18	618.169
#272	LMO4	9	19	28	1798.617
#273	RARA	9	12	21	1477.443
#274	SREBF1	9	12	21	503.741
#275	TBR1	9	16	25	1897.369
#276	VTN	9	11	20	1159.44
#277	ARNTL	9	18	27	1203.371
#278	HOXA11	9	7	16	1256.743
#279	ZSCAN18	9	14	23	1189.687
#280	HOXC4	9	11	20	2006.593
#281	PHTF1	9	10	19	468.025
#282	JUN	9	10	19	1412.734
#283	ZNF140	9	14	23	1559.817
#284	NKX2-1	9	7	16	690.864
#285	ONECUT1	9	11	20	827.567
#286	ETV5	9	9	18	1579.919
#287	MEF2A	8	6	14	933.685
#288	ELK3	8	19	27	1497.813
#289	MEOX1	8	16	24	1593.202
#290	ELF4	8	19	27	931.651
#291	TFCP2	8	15	23	3177.653
#292	NPAS1	8	17	25	1883.807
#293	SREBF2	8	15	23	935.58
#294	HOXA4	8	7	15	825.708
#295	ZNF287	8	17	25	1875.608
#296	ZNF33B	8	14	22	3286.196
#297	C11orf9	8	22	30	1103.581
#298	CREBZF	8	11	19	1191.81
#299	ZNF91	8	10	18	748.567
#300	LHX2	8	7	15	475.198
#301	NR2F6	8	19	27	1380.929
#302	PRRX1	8	13	21	614.259
#303	ZNF189	8	15	23	1223.21
#304	ZHX2	8	12	20	1100.375
#305	HNF1A	8	11	19	1005.938
#306	HOXB6	8	9	17	687.353
#307	POU1F1	8	12	20	839.577
#308	GTF2H4	8	13	21	1193.822
#309	NKX2-5	8	9	17	515.352
#310	ZFHX3	8	17	25	1174.115
#311	HOXA7	8	5	13	1085.254
#312	ZIC3	8	13	21	986.702
#313	TGIF1	8	16	24	1632.195
#314	TCF15	7	9	16	1115.986
#315	HOXD4	7	9	16	304.588
#316	MEOX2	7	13	20	430.895
#317	MLL	7	11	18	749.871
#318	NFATC1	7	10	17	1129.284
#319	NFKB1	7	9	16	615.025
#320	NFE2L1	7	7	14	198.935
#321	MMP14	7	25	32	1068.789
#322	MYBL2	7	8	15	153.821
#323	ALX1	7	15	22	1350.49
#324	NEUROD1	7	10	17	1945.754
#325	RAX	7	12	19	492.346
#326	CREB5	7	12	19	668.34
#327	NR2F2	7	11	18	742.162
#328	HIF3A	7	15	22	1090.114
#329	HMGB2	7	11	18	293.35
#330	MSRB2	7	17	24	1469.214
#331	GATA2	7	17	24	871.264
#332	HOPX	7	17	24	975.538
#333	HOXB5	7	7	14	681.234
#334	ZNF643	7	14	21	816.266
#335	HOXA9	7	10	17	754.249
#336	CUX2	7	14	21	1069.047
#337	TFEB	7	19	26	2086.748
#338	ATF5	7	17	24	637.397
#339	NR4A2	7	7	14	256.801
#340	ELK1	6	11	17	574.212
#341	ELF5	6	8	14	376.964
#342	HEY2	6	23	29	938.385
#343	FOXJ1	6	12	18	373.631
#344	CSRNP3	6	16	22	1140.572
#345	HOXA5	6	7	13	1012.535
#346	CTBP1	6	13	19	1159.209
#347	RCAN1	6	14	20	965.383
#348	TBX3	6	16	22	336.213
#349	ARNT2	6	12	18	644.198
#350	RERE	6	10	16	952.609
#351	GAS7	6	18	24	528.828
#352	CDX2	6	10	16	337.122
#353	NFAT5	6	17	23	1334.444
#354	ETS2	6	13	19	887.667
#355	MTA2	6	18	24	3323.041
#356	NR2C1	6	18	24	1786.768
#357	HOXD10	6	7	13	938.941
#358	POU3F1	6	14	20	699.795
#359	SOX18	6	15	21	1990.31
#360	NR4A3	6	8	14	128.861
#361	GATA3	6	19	25	1110.857
#362	HR	6	16	22	772.6
#363	ZNF323	6	10	16	175.523
#364	HIC1	6	10	16	497.883
#365	TLX2	6	11	17	653.24
#366	TBX1	6	12	18	932.268
#367	MLLT10	6	12	18	1336.061
#368	ST18	6	14	20	786.921
#369	BNC1	6	16	22	1388.063
#370	MYOD1	6	13	19	878.629
#371	ZNF117	6	13	19	1660.357
#372	SRY	6	10	16	808.103
#373	TBX6	6	12	18	1760.905
#374	BARX1	6	9	15	640.393
#375	SLC26A3	6	10	16	979.071
#376	ZNF268	5	9	14	448.027
#377	RFXAP	5	9	14	246.15
#378	TSC22D2	5	14	19	431.405
#379	HOXC13	5	14	19	1262.56
#380	POU4F1	5	6	11	476.524
#381	ECSIT	5	13	18	1677.459
#382	CREBBP	5	11	16	531.108
#383	MEIS2	5	15	20	1300.946
#384	ISL1	5	11	16	2102.902
#385	SOX15	5	12	17	268.781
#386	ZNF135	5	17	22	710.777
#387	SOX2	5	18	23	1870.565
#388	HOXD9	5	11	16	937.698
#389	NOTCH1	5	12	17	363.507
#390	NR5A1	5	12	17	1379.896
#391	EVX1	5	10	15	392.857
#392	SOX13	5	15	20	642.342
#393	SIX1	5	15	20	901.789
#394	ZSCAN2	5	14	19	2972.444
#395	NFYA	5	13	18	518.604
#396	FOXC1	5	10	15	515.576
#397	NKX3-2	5	11	16	959.307
#398	FOXP3	5	14	19	717.6
#399	LMX1B	5	7	12	477.949
#400	HNF4G	5	13	18	774.971
#401	HOXD13	5	14	19	864.067
#402	CITED1	5	13	18	942.804
#403	HAND2	5	13	18	490.515
#404	SOX5	5	20	25	593.404
#405	MYT1	5	11	16	1238.601
#406	NR2E1	4	14	18	404.407
#407	ESRRG	4	16	20	374.09
#408	USF2	4	13	17	856.273
#409	PDX1	4	16	20	1135.511
#410	POU4F3	4	10	14	548.321
#411	ETV2	4	15	19	969.317
#412	E2F2	4	16	20	1148.55
#413	HOXB8	4	11	15	485.194
#414	GBX1	4	16	20	1467.384
#415	SCAND2	4	13	17	1519.916
#416	ZBTB17	4	11	15	1540.976
#417	HOXC8	4	14	18	1721.145
#418	ZIC1	4	21	25	682.748
#419	HEYL	4	13	17	1212.466
#420	ZNF174	4	8	12	164.385
#421	IRF5	4	15	19	3162.128
#422	ETV3	4	15	19	699.735
#423	CLOCK	4	15	19	1848.982
#424	CSDA	4	13	17	856.82
#425	DMRT1	4	14	18	378.03
#426	STAT2	4	17	21	362.288
#427	GBX2	4	14	18	1186.097
#428	SIM2	4	15	19	459.268
#429	HOXB2	4	14	18	301.286
#430	POU3F2	4	11	15	1155.807
#431	ZNF165	4	13	17	440.026
#432	TP53	4	15	19	783.774
#433	LHX1	4	16	20	1428.008
#434	POU2F3	4	10	14	608.06
#435	NFIX	3	13	16	1179.599
#436	HNF4A	3	13	16	703.33
#437	POU3F3	3	17	20	1632.882
#438	SMAD9	3	13	16	251.581
#439	MAFK	3	11	14	1273.866
#440	ZNF154	3	11	14	325.209
#441	ZSCAN12	3	7	10	368.671
#442	ARNT	3	17	20	345.778
#443	ESR2	3	13	16	297.991
#444	EGR4	3	11	14	127.178
#445	PITX3	3	10	13	727.816
#446	MYT1L	3	6	9	512.537
#447	HESX1	3	11	14	508.325
#448	TBX2	3	14	17	679.469
#449	IKZF1	3	13	16	355.267
#450	PRDM2	3	10	13	636.048
#451	SCRT1	3	15	18	694.268
#452	HSF4	3	15	18	671.714
#453	HOXD12	3	10	13	467.213
#454	FOXC2	3	12	15	441.651
#455	BLZF1	3	11	14	733.243
#456	ZNF215	3	14	17	338.606
#457	ZNF155	3	10	13	748.402
#458	NANOG	3	13	16	255.945
#459	PAX6	3	22	25	970.861
#460	ZNF202	3	15	18	337.172
#461	SMAD1	3	15	18	246.064
#462	PURA	3	14	17	1364.968
#463	SOX10	3	15	18	418.803
#464	HHEX	3	9	12	382.449
#465	POU6F2	3	10	13	249.226
#466	AR	3	14	17	428.104
#467	NKX3-1	3	14	17	758.641
#468	SHOX	3	15	18	247.433
#469	PKNOX1	3	13	16	152.708
#470	FOXD1	3	9	12	990.594
#471	RORA	3	18	21	400.159
#472	ARNTL2	3	15	18	323.154
#473	RORB	3	14	17	734.364
#474	NR6A1	2	16	18	264.615
#475	NRL	2	12	14	606.869
#476	TP73	2	11	13	741.866
#477	POU2F2	2	13	15	359.67
#478	KLF10	2	14	16	121.787
#479	REST	2	20	22	1179.051
#480	FOXN1	2	11	13	163.75
#481	NFE2	2	17	19	793.457
#482	RUNX3	2	22	24	197.536
#483	EMX1	2	11	13	126.186
#484	TAF4	2	10	12	213.174
#485	TFAP2B	2	13	15	474.44
#486	KLF12	2	16	18	102.158
#487	HOXA1	2	15	17	360.762
#488	TFDP3	2	19	21	452
#489	FOXE1	2	9	11	193.648
#490	HCFC1	2	17	19	735.92
#491	FOXB1	2	9	11	218.447
#492	TBX4	2	11	13	485.958
#493	RFX1	2	17	19	630.056
#494	RARB	1	11	12	109.435
#495	HOXB13	1	18	19	157.121
#496	TAL1	1	15	16	60.227
#497	FOXD3	1	13	14	262.686
#498	HOXA3	0	15	15	0
#499	ZNF41	0	7	7	0
#500	LHX5	0	15	15	0