Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NR3C1	59	4	63	241.058
#2	SNAI2	47	1	48	22.5
#3	SALL1	44	2	46	34.919
#4	HHEX	37	6	43	200.957
#5	MYC	36	6	42	4408.765
#6	NR1I3	36	4	40	72.514
#7	VTN	35	1	36	38.115
#8	AR	34	7	41	164.859
#9	NR1H4	34	2	36	46.349
#10	BATF3	34	11	45	1795.223
#11	TCF4	33	6	39	314.18
#12	KLF11	32	11	43	6424.388
#13	GTF2IRD1	31	7	38	250.744
#14	ATF5	31	6	37	113.862
#15	SOX9	31	4	35	2054.53
#16	MAFF	31	7	38	189.182
#17	AEBP1	31	4	35	269.287
#18	GRHL2	31	5	36	1276.672
#19	CDX2	30	10	40	1471.862
#20	ESR1	30	9	39	220.368
#21	HLF	29	7	36	143.945
#22	NFIC	29	10	39	11124.788
#23	PLAGL2	27	8	35	319.604
#24	PEG3	27	10	37	215.765
#25	E2F8	27	6	33	589.795
#26	NFE2L3	26	8	34	742.98
#27	BHLHE41	26	6	32	1094.303
#28	BCL6	25	4	29	615.679
#29	GATA4	24	6	30	117.942
#30	ZEB2	24	6	30	835.126
#31	TCF7	24	10	34	504.656
#32	HCLS1	24	5	29	1022.273
#33	PROX1	24	13	37	778.128
#34	EGR3	23	8	31	2140.776
#35	PPARG	23	11	34	1118.248
#36	KLF5	23	4	27	581.424
#37	SNAPC4	22	9	31	513.771
#38	LHX2	22	12	34	1639.146
#39	CEBPA	22	7	29	619.172
#40	SIX1	22	11	33	4734.68
#41	HOXB9	22	10	32	3473.483
#42	MAFB	22	4	26	145.937
#43	LEF1	21	12	33	1500.626
#44	RORA	21	11	32	305.808
#45	MSL3	21	10	31	487.879
#46	JUN	21	9	30	515.569
#47	RUNX3	20	10	30	1870.35
#48	ZFPM2	20	10	30	517.774
#49	CUX2	20	3	23	54.476
#50	TFEC	20	6	26	969.242
#51	NR5A2	20	9	29	268.02
#52	FLI1	20	8	28	1317.596
#53	EPAS1	20	13	33	1904.709
#54	TWIST1	19	5	24	290.587
#55	HMGB2	19	6	25	117.792
#56	JUND	19	12	31	8372.192
#57	HEY1	19	10	29	2570.179
#58	ETV4	19	9	28	824.081
#59	ARNTL2	19	11	30	2424.422
#60	ONECUT1	19	12	31	247.963
#61	RORC	19	10	29	481.409
#62	TCF21	19	17	36	5115.34
#63	ZFHX4	19	11	30	6609.849
#64	ELF3	19	9	28	3609.9
#65	ETV5	19	9	28	2806.126
#66	HMX1	18	9	27	1949.705
#67	CITED2	18	10	28	205.297
#68	RXRA	18	5	23	53.009
#69	SATB2	18	12	30	339.163
#70	EGR2	18	12	30	1840.626
#71	NR2F2	18	7	25	10857.927
#72	TP53	18	12	30	9238.17
#73	GLI2	18	10	28	976.563
#74	ELF1	18	12	30	508.922
#75	E2F5	18	7	25	280.262
#76	SMAD4	18	9	27	806.386
#77	FOS	18	6	24	490.371
#78	ZNF117	18	8	26	947.499
#79	PTTG1	18	8	26	385.838
#80	GCM1	18	12	30	1571.782
#81	MLLT10	17	10	27	1995.2
#82	TBX3	17	15	32	2122.349
#83	TRIM22	17	9	26	773.912
#84	STAT1	17	10	27	1422.369
#85	RARB	17	13	30	738.641
#86	FOXA1	17	17	34	2696.66
#87	CEBPD	17	8	25	572.603
#88	CSDA	17	10	27	1142.125
#89	PITX1	17	11	28	722.963
#90	NR2F1	17	13	30	3901.612
#91	ELF4	17	6	23	1963.676
#92	ZGPAT	17	7	24	100.302
#93	PPBPL2	16	11	27	2599.229
#94	MSX1	16	12	28	664.276
#95	POU5F1B	16	8	24	486.602
#96	HEY2	16	9	25	1074.582
#97	OVOL1	16	14	30	2201.324
#98	ARID3A	16	5	21	384.203
#99	SPI1	16	6	22	1007.66
#100	ZNF165	16	13	29	10268.859
#101	PHF1	16	9	25	4370.384
#102	SOX18	16	12	28	1255.158
#103	MLXIPL	16	11	27	1437.8
#104	PLAG1	16	9	25	887.512
#105	HOXB7	16	9	25	2030.134
#106	HOXB6	16	6	22	602.481
#107	PRRX1	16	7	23	1009.528
#108	BHLHE40	15	10	25	689.838
#109	GSC2	15	12	27	1727.374
#110	ARNT2	15	16	31	1776.211
#111	MEIS1	15	9	24	2155.566
#112	KLF4	15	10	25	732.015
#113	MEIS2	15	9	24	1577.945
#114	CREB3L1	15	12	27	1227.418
#115	DBP	15	8	23	867.723
#116	SOX4	15	9	24	210.36
#117	FOXA2	15	7	22	759.038
#118	HOXA10	15	6	21	4190.11
#119	ASCL2	15	13	28	442.015
#120	NR1I2	15	17	32	12868.87
#121	TRPS1	15	9	24	840.122
#122	SOX13	15	14	29	1638.363
#123	BACH2	15	13	28	3468.761
#124	HOXB2	15	12	27	1128.344
#125	WNT5A	15	14	29	1385.726
#126	SCAND2	15	15	30	1924.943
#127	HMGA2	15	14	29	1781.12
#128	ZNF434	15	10	25	526.583
#129	ZEB1	15	11	26	4338.309
#130	NKX3-2	15	14	29	3579.259
#131	ZNF238	15	8	23	1191.108
#132	HOXA11	15	9	24	288.445
#133	VDR	15	11	26	807.9
#134	HOXA5	14	5	19	237.307
#135	HNF1B	14	12	26	1259.167
#136	NR2C1	14	12	26	1669.058
#137	CREB5	14	11	25	2322.215
#138	TCF3	14	8	22	217.969
#139	ZNF174	14	10	24	1670.571
#140	MAF	14	10	24	370.363
#141	ERG	14	8	22	417.424
#142	NFIX	14	9	23	844.037
#143	HMGA1	14	7	21	181.749
#144	MEOX2	14	8	22	286.104
#145	FOXF2	14	8	22	849.281
#146	CBL	14	9	23	1082.365
#147	ONECUT2	14	11	25	1646.945
#148	ELK4	14	12	26	1302.342
#149	HSF1	14	8	22	1871.661
#150	KLF1	14	11	25	2023.948
#151	TRIM29	14	13	27	592.729
#152	PHOX2A	14	12	26	1420.937
#153	MNX1	14	8	22	1059.682
#154	ZNF83	13	12	25	816.058
#155	SOX30	13	16	29	2081.296
#156	MYBL2	13	7	20	185.131
#157	RUNX1	13	14	27	2148.821
#158	HOPX	13	10	23	1815.798
#159	TBX6	13	8	21	1216.468
#160	RARA	13	12	25	1352.762
#161	KLF9	13	13	26	1558.557
#162	MYCL1	13	12	25	1028.27
#163	FOSL1	13	8	21	244.743
#164	MEIS3P1	13	9	22	330.152
#165	POU4F2	13	16	29	1920.029
#166	HOXD11	13	7	20	310.716
#167	VAV1	13	10	23	426.72
#168	NEUROG1	13	9	22	1410.716
#169	SPDEF	13	10	23	2445.133
#170	CREBBP	12	10	22	1454.159
#171	FOXO3	12	12	24	1364.19
#172	ZNF157	12	14	26	2331.501
#173	NR5A1	12	10	22	1251.79
#174	FOSL2	12	18	30	939.175
#175	SPIB	12	15	27	3229.663
#176	HOXD4	12	9	21	969.421
#177	MYF6	12	15	27	2971.692
#178	NPAT	12	14	26	2869.639
#179	SHOX	12	11	23	1151.102
#180	HNF1A	12	12	24	989.394
#181	LASS6	12	12	24	544.625
#182	CBFA2T2	12	14	26	1390.687
#183	HMG20B	12	12	24	1648.163
#184	LHX1	12	15	27	1580.738
#185	HNF4G	12	12	24	1602.786
#186	PRRX2	12	10	22	474.674
#187	ZIC1	12	13	25	1837.471
#188	NKX2-8	11	13	24	1446.387
#189	HOXA9	11	7	18	1365.792
#190	WT1	11	11	22	1066.068
#191	DMRT1	11	14	25	1313.667
#192	HNF4A	11	15	26	464.738
#193	HOXA7	11	5	16	139.168
#194	TFAP2A	11	16	27	970.541
#195	PITX2	11	14	25	591.284
#196	TSHZ2	11	15	26	570.836
#197	TP63	11	17	28	2051.122
#198	NEUROD2	11	11	22	2672.233
#199	PGR	11	12	23	2231.842
#200	ZNF167	11	9	20	656.296
#201	NR2E3	11	12	23	1303.646
#202	ETV1	11	13	24	1322.745
#203	POU3F2	11	13	24	3068.558
#204	HIF3A	11	14	25	1966.241
#205	FOXM1	11	10	21	484.934
#206	MLL	11	9	20	570.639
#207	PBX1	11	8	19	1089.267
#208	ALX1	11	8	19	946.662
#209	ZNF93	11	7	18	606.885
#210	HOXC11	11	9	20	840.408
#211	FOXE3	11	8	19	1552.253
#212	NFAT5	11	11	22	315.311
#213	ETV2	11	7	18	780.699
#214	HOXB1	11	9	20	1074.122
#215	TCF12	11	17	28	1512.142
#216	C11orf9	11	10	21	968.482
#217	NKX3-1	11	15	26	2530.82
#218	ZBTB48	11	13	24	1544.976
#219	E2F1	11	10	21	311.602
#220	SATB1	11	13	24	1051.067
#221	ZNF45	11	8	19	933.002
#222	HOXC4	11	15	26	1999.518
#223	BCL11B	11	10	21	232.399
#224	EGR1	11	10	21	854.723
#225	SOX17	11	11	22	957.992
#226	IKZF3	10	9	19	981.845
#227	PPARD	10	13	23	938.012
#228	BCL3	10	11	21	1128.54
#229	FOXH1	10	12	22	788.61
#230	PAX4	10	12	22	1023.812
#231	SIX3	10	14	24	914.806
#232	NFATC1	10	14	24	1498.664
#233	SIM2	10	13	23	1905.351
#234	FOXD2	10	8	18	668.217
#235	POU6F1	10	9	19	763.049
#236	MYOD1	10	7	17	527.225
#237	SIX2	10	18	28	1705.653
#238	SOX1	10	12	22	1351.892
#239	RXRG	10	11	21	1395.104
#240	CBFA2T3	10	15	25	604.945
#241	RBPJL	10	14	24	2190.358
#242	RXRB	10	13	23	2110.973
#243	ESRRA	10	13	23	1923.064
#244	NFYA	10	13	23	1522.247
#245	FOXF1	10	8	18	1493.312
#246	ZNF444	10	13	23	1658.718
#247	ZIC3	10	12	22	1867.039
#248	DLX4	10	13	23	1500.874
#249	FOXP3	10	13	23	1794.634
#250	LMX1B	10	12	22	974.729
#251	FEV	10	11	21	896.683
#252	EHF	10	13	23	955.485
#253	RFX3	10	10	20	1627.993
#254	RB1	10	14	24	807.189
#255	NR2E1	10	11	21	1000.587
#256	NPAS2	10	13	23	459.088
#257	TAF13	10	12	22	1849.018
#258	HOXB5	10	4	14	344.026
#259	HOXC10	10	12	22	1789.408
#260	MYF5	10	13	23	1652.525
#261	SRY	10	11	21	720.265
#262	TSC22D2	10	14	24	926.063
#263	TBX21	10	12	22	1809.535
#264	TAF4B	10	11	21	2149.869
#265	SREBF1	10	12	22	456.989
#266	MMP14	10	14	24	1000.51
#267	ETS2	10	11	21	619.869
#268	ZNF202	10	14	24	1210.573
#269	PAX6	10	17	27	1549.508
#270	HOXA3	10	11	21	1618.473
#271	POU3F3	9	12	21	830.857
#272	ZNF134	9	18	27	2019.998
#273	PDX1	9	12	21	944.174
#274	FOXE1	9	14	23	1095.623
#275	SCRT1	9	14	23	1484.108
#276	NFIB	9	10	19	1480.039
#277	ELF5	9	21	30	1661.958
#278	CDKN2A	9	14	23	1316.108
#279	REL	9	12	21	458.208
#280	MYT1	9	13	22	1204.052
#281	SIM1	9	10	19	323.561
#282	ARNT	9	8	17	478.524
#283	KDM5B	9	11	20	908.29
#284	BARX1	9	17	26	1678.882
#285	MYCN	9	16	25	1512.046
#286	MZF1	9	15	24	665.16
#287	FOXN1	9	10	19	765.608
#288	SOX2	9	12	21	1583.553
#289	POU3F4	9	12	21	1001.294
#290	EVX1	9	15	24	644.426
#291	ZNF215	9	9	18	175.481
#292	EGR4	9	18	27	1650.465
#293	HOXA6	9	10	19	422.85
#294	THRA	9	17	26	869.191
#295	RFXAP	9	14	23	3368.927
#296	ATOH1	9	11	20	1062.064
#297	GAS7	9	10	19	314.11
#298	SP4	9	12	21	1176.404
#299	BATF	9	10	19	739.39
#300	HOXA4	9	12	21	1836.496
#301	TP73	9	12	21	1616.504
#302	ZNF643	9	14	23	1153.723
#303	FOXB1	9	7	16	755.03
#304	KLF15	9	7	16	68.925
#305	SOX15	9	9	18	2029.499
#306	NR3C2	9	15	24	1213.418
#307	HSF4	9	17	26	1213.348
#308	MEF2C	9	10	19	768.96
#309	NR0B1	9	14	23	1666.656
#310	HEYL	9	15	24	1685.368
#311	MTA2	9	12	21	928.35
#312	STRN3	9	6	15	741.633
#313	POU2F3	9	12	21	1086.425
#314	HOXD1	9	15	24	1162.841
#315	TFEB	9	10	19	525.028
#316	HMBOX1	8	12	20	1322.122
#317	OLIG2	8	19	27	1683.319
#318	CRX	8	13	21	1029.868
#319	RCAN1	8	12	20	2975.765
#320	NKX2-5	8	16	24	1264.378
#321	PRDM2	8	11	19	670.958
#322	PAX5	8	10	18	527.394
#323	TFCP2L1	8	12	20	304.496
#324	RBCK1	8	10	18	464.943
#325	SOX5	8	15	23	220.156
#326	E2F4	8	12	20	1414.419
#327	HOXD12	8	11	19	974.268
#328	CSRNP3	8	13	21	778.089
#329	ZNF81	8	15	23	6359.704
#330	AFF1	8	10	18	636.776
#331	HOXC8	8	10	18	863.341
#332	THRB	8	10	18	568.789
#333	NKX6-1	8	16	24	1535.686
#334	TFAP2B	8	14	22	670.295
#335	RAX	8	10	18	399.395
#336	NANOG	8	13	21	965.916
#337	SOX11	8	12	20	1333.314
#338	FOXL1	8	15	23	920.698
#339	TLX1	8	13	21	701.402
#340	FOXJ1	8	15	23	740.835
#341	HOXD10	8	8	16	458.229
#342	SLC26A3	8	16	24	995.466
#343	PAX8	8	17	25	1150.749
#344	CLOCK	8	9	17	952.776
#345	NKX2-1	8	15	23	1231.48
#346	PKNOX1	8	14	22	823.885
#347	ZNF155	8	12	20	832.045
#348	NFATC4	8	12	20	468.728
#349	BUD31	8	12	20	982.684
#350	HES1	8	12	20	1022.442
#351	IRX5	8	13	21	514.564
#352	PURA	8	6	14	225.944
#353	FOXG1	8	20	28	1090.249
#354	TFAP2C	8	15	23	1366.582
#355	NR4A1	8	9	17	139.075
#356	POU6F2	8	14	22	1285.072
#357	ZNF3	8	14	22	974.636
#358	FUBP1	7	16	23	770.783
#359	ZSCAN18	7	18	25	1662.375
#360	TBR1	7	16	23	3926.269
#361	GBX2	7	12	19	1200.737
#362	NR2F6	7	14	21	591.296
#363	ZNF446	7	12	19	857.788
#364	NR6A1	7	17	24	327.263
#365	MECOM	7	14	21	848.893
#366	KLF12	7	10	17	724.55
#367	HOXA2	7	14	21	506.067
#368	HIC1	7	13	20	722.219
#369	HOXD9	7	11	18	360.167
#370	MEF2D	7	12	19	642.459
#371	ELK1	7	11	18	1000.189
#372	TSC22D4	7	17	24	732.111
#373	SOX21	7	14	21	1633.211
#374	VAX2	7	12	19	533.221
#375	TAL1	7	14	21	1224.528
#376	NR4A2	7	10	17	581.038
#377	RUNX1T1	7	11	18	415.085
#378	GATA1	7	14	21	1565.658
#379	HESX1	7	12	19	1149.948
#380	TLX2	7	11	18	1808.497
#381	PTH	7	13	20	1355.35
#382	SP140	7	11	18	483.937
#383	ZNF236	7	11	18	661.525
#384	TLX3	7	16	23	1014.362
#385	TBX2	7	13	20	820.207
#386	ZNF135	7	15	22	754.624
#387	MXD1	7	14	21	2900.583
#388	POU1F1	7	17	24	1621.969
#389	ISL1	7	17	24	767.536
#390	DLX2	7	16	23	1686.98
#391	GATA3	7	15	22	1410.573
#392	ETS1	7	17	24	1424.042
#393	TADA2A	7	10	17	665.105
#394	HOXC5	7	11	18	1190.245
#395	RORB	7	12	19	1036.456
#396	CREBZF	6	15	21	2659.401
#397	NFKB2	6	17	23	1241.984
#398	HCFC1	6	14	20	448.262
#399	FOXL2	6	18	24	1097.582
#400	POU2F2	6	14	20	1075.941
#401	ATF6B	6	14	20	877.24
#402	POU4F1	6	13	19	485.731
#403	HOXB8	6	6	12	77.712
#404	HOXB3	6	16	22	376.205
#405	ZNF80	6	8	14	369.417
#406	POU3F1	6	16	22	915.228
#407	NR4A3	6	13	19	816.108
#408	HOXD13	6	18	24	1246.361
#409	TCF15	6	15	21	765.898
#410	SNAPC5	6	12	18	1061.955
#411	TBX4	6	12	18	890.385
#412	ESRRG	6	16	22	1057.486
#413	PBX2	6	15	21	976.302
#414	BRD8	6	16	22	1106.097
#415	MYT1L	6	22	28	1258.107
#416	SIX6	6	16	22	891.985
#417	LHX3	6	13	19	1115.872
#418	HOXD3	6	20	26	876.684
#419	ZFP36L1	6	13	19	978.562
#420	TFAP4	6	12	18	558.186
#421	SMAD3	6	16	22	1823.036
#422	TADA3	6	16	22	816.82
#423	NEUROD1	6	13	19	692.106
#424	LMO4	6	10	16	811.002
#425	ZNF154	6	19	25	1074.479
#426	RARG	6	12	18	1000.486
#427	E2F2	6	13	19	576.323
#428	ZNF132	6	10	16	274.653
#429	ZFP37	6	16	22	717.902
#430	T	6	19	25	1196.114
#431	ZNF639	6	14	20	749.85
#432	BNC1	6	13	19	613.384
#433	VSX1	6	11	17	631.758
#434	MEOX1	6	14	20	477.032
#435	TBX10	6	10	16	1287.105
#436	NPAS1	6	18	24	952.926
#437	IKZF1	6	12	18	1205.503
#438	STAT2	5	10	15	642.043
#439	ZBTB17	5	11	16	712.221
#440	YY1	5	13	18	592.339
#441	DLX6	5	10	15	434.276
#442	TCF25	5	13	18	669.137
#443	LZTS1	5	12	17	945.689
#444	SMAD6	5	11	16	1364.209
#445	VENTX	5	14	19	657.39
#446	HOXB13	5	20	25	358.503
#447	SMAD9	5	15	20	524.134
#448	BLZF1	5	14	19	738.199
#449	ZSCAN2	5	10	15	373.079
#450	SIX5	5	13	18	466.065
#451	TAF4	5	13	18	323.781
#452	EN1	5	18	23	1291.264
#453	ALX4	5	8	13	341.901
#454	ZNF192	5	13	18	300.92
#455	CREM	5	13	18	499.387
#456	IRF4	5	21	26	1377.411
#457	PKNOX2	4	13	17	450.047
#458	ZNF287	4	11	15	406.286
#459	PHOX2B	4	14	18	980.04
#460	RERE	4	13	17	438.218
#461	HOXA1	4	13	17	237.63
#462	ST18	4	15	19	2331.356
#463	POU4F3	4	16	20	661.999
#464	MYOG	4	15	19	258.927
#465	ASCL1	4	11	15	432.422
#466	HOXC13	4	9	13	263.052
#467	HAND2	4	14	18	435.931
#468	SRF	4	12	16	706.745
#469	MAX	4	12	16	1327.671
#470	TEF	4	14	18	186.024
#471	IRX4	4	18	22	804.979
#472	FOSB	4	11	15	303.066
#473	ZHX3	4	19	23	556.219
#474	SOX10	4	13	17	765.584
#475	HR	4	10	14	298.885
#476	IRF5	4	15	19	528.488
#477	REST	4	19	23	498.284
#478	FOXI1	4	16	20	642.155
#479	EN2	4	13	17	1128.594
#480	EMX1	4	14	18	1088.326
#481	PAX7	3	14	17	493.16
#482	CTBP1	3	12	15	408.769
#483	FOXC2	3	12	15	326.166
#484	MSX2	3	16	19	296.665
#485	TFDP3	3	19	22	490.501
#486	ZNF500	3	11	14	198.667
#487	FOXD1	3	18	21	369.391
#488	TBX5	3	11	14	220.619
#489	ZSCAN12	3	14	17	1108.433
#490	CITED1	3	17	20	341.725
#491	NFE2	3	15	18	459.137
#492	PAX3	2	12	14	234.415
#493	RUNX2	2	18	20	349.867
#494	ATF7	2	11	13	149.004
#495	ESR2	2	13	15	380.557
#496	NRL	2	17	19	214.751
#497	ALX3	2	14	16	407.986
#498	ETV3	2	17	19	214.611
#499	TBX1	1	20	21	389.733
#500	ZNF41	0	18	18	0