Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXE1	53	1	54	16.438
#2	ZEB2	52	3	55	2687.743
#3	CITED2	51	7	58	1894.96
#4	TP63	48	1	49	622.486
#5	SOX2	43	4	47	146.02
#6	HOPX	42	7	49	2576.781
#7	EPAS1	40	8	48	987.442
#8	GAS7	39	4	43	437.711
#9	SNAI2	39	7	46	901.017
#10	KLF5	38	3	41	134.635
#11	TFEC	38	5	43	718.569
#12	BATF	36	10	46	2084.497
#13	BHLHE41	36	9	45	347.772
#14	LMO4	36	11	47	1149.247
#15	E2F3	35	10	45	4302.369
#16	PROX1	34	7	41	788.287
#17	FOSL2	33	10	43	2500.043
#18	BNC1	33	5	38	424.663
#19	KLF6	33	11	44	675.875
#20	CEBPB	33	5	38	598.414
#21	BHLHE40	33	1	34	17.526
#22	PRRX1	33	6	39	714.711
#23	GLI2	32	7	39	887.519
#24	JUNB	32	5	37	452.709
#25	FOXM1	32	12	44	1453.391
#26	NR2F2	31	10	41	1346.177
#27	NFE2L2	31	4	35	90.456
#28	MYC	31	9	40	1056.876
#29	TRIM29	30	5	35	445.89
#30	NKX2-1	30	8	38	559.986
#31	IRF6	30	4	34	2164.776
#32	E2F6	29	12	41	2287.139
#33	FLI1	29	11	40	2383.629
#34	XBP1	29	11	40	679.949
#35	TRIM22	29	3	32	109.041
#36	E2F1	28	19	47	2474.008
#37	MEIS1	28	7	35	965.035
#38	ARNT	28	18	46	2293.803
#39	SPIB	28	5	33	299.254
#40	ZFHX4	27	9	36	1318.943
#41	ZNF45	27	12	39	1416.083
#42	NPAT	26	12	38	2155.457
#43	SPI1	26	9	35	652.331
#44	ALX1	26	12	38	1299.17
#45	TCF4	25	14	39	1906.515
#46	ST18	25	10	35	1058.305
#47	NR1H3	25	2	27	34.684
#48	ERF	25	9	34	1270.984
#49	FOS	25	6	31	476.624
#50	WNT5A	25	10	35	958.17
#51	MEF2C	25	11	36	3062.848
#52	MYNN	25	13	38	623.018
#53	GATA6	25	12	37	1327.801
#54	FOSL1	25	13	38	1005.874
#55	ETV5	24	12	36	2968.184
#56	HCLS1	24	11	35	1246.79
#57	RXRB	24	16	40	2045.402
#58	AEBP1	24	4	28	423.118
#59	HOXB2	24	11	35	2446.795
#60	TWIST1	23	8	31	309.251
#61	ZBTB38	23	8	31	986.209
#62	EN1	23	13	36	2479.797
#63	VTN	23	10	33	1685.866
#64	MGA	23	14	37	2344.1
#65	BCL11B	23	7	30	301.787
#66	RUNX3	23	12	35	1489.287
#67	TSC22D1	22	11	33	639.292
#68	SOX9	22	9	31	1215.422
#69	ZFPM2	22	8	30	174.549
#70	HEY1	22	12	34	1094.075
#71	RORA	22	16	38	1164.241
#72	IRF7	22	7	29	719.902
#73	EHF	22	15	37	1131.22
#74	CBFA2T2	22	11	33	1028.735
#75	SIX2	22	14	36	804.267
#76	ELF3	22	11	33	1958.59
#77	ARNTL2	21	7	28	684.868
#78	ETV1	21	17	38	2370.87
#79	POU5F1B	21	13	34	1058.292
#80	NFYB	21	13	34	1861.519
#81	ZNF83	21	15	36	1109.426
#82	HAND1	21	8	29	993.052
#83	SOX4	21	10	31	2066.828
#84	AHR	21	12	33	1548.289
#85	RARG	21	9	30	962.486
#86	HOXA10	21	12	33	638.923
#87	TCFL5	20	10	30	910.891
#88	TEAD4	20	11	31	1240.203
#89	TFAP2C	20	12	32	1075.959
#90	ELF1	20	10	30	1681.913
#91	NFIC	20	18	38	2102.661
#92	ZBTB48	20	16	36	2081.942
#93	TFAP2A	20	12	32	1417.598
#94	MSC	20	17	37	2212.492
#95	NR4A2	20	10	30	1031.924
#96	VSX1	20	11	31	1813.901
#97	ZSCAN16	20	13	33	2172.977
#98	JUN	20	12	32	1515.187
#99	MLXIPL	20	8	28	833.84
#100	FOXA2	20	16	36	1727.545
#101	ECSIT	20	8	28	501.509
#102	PITX1	19	10	29	299.662
#103	TBX3	19	21	40	1049.579
#104	HOXB6	19	8	27	568.813
#105	SOX13	19	17	36	2037.257
#106	FOXI1	19	7	26	501.3
#107	DBP	19	14	33	1850.821
#108	TFEB	19	15	34	1127.598
#109	FOXA1	19	11	30	1116.996
#110	ZNF140	19	9	28	2223.778
#111	ZNF277	19	6	25	895.508
#112	LASS6	19	18	37	1147.297
#113	IRF9	19	6	25	240.473
#114	NFIB	18	23	41	1613.453
#115	KLF15	18	12	30	1243.427
#116	RAX	18	7	25	719.374
#117	ARNTL	18	10	28	1255.52
#118	SOX15	18	9	27	190.918
#119	SMAD9	18	15	33	1289.293
#120	KLF9	18	14	32	1150.978
#121	HMGB2	18	15	33	788.574
#122	TFE3	18	11	29	1844.261
#123	ZNF238	18	13	31	1014.628
#124	MYCL1	18	17	35	1503.143
#125	RXRA	18	15	33	1435.688
#126	ZEB1	18	21	39	2292.98
#127	FOXC1	17	10	27	1782.369
#128	DLX2	17	15	32	1280.976
#129	HOXB13	17	13	30	1399.844
#130	HMGA1	17	18	35	1256.759
#131	MMP14	17	8	25	198.651
#132	ZNF187	17	8	25	916.169
#133	TBR1	17	13	30	2114.962
#134	YEATS4	17	12	29	1577.283
#135	VAX2	17	14	31	1332.981
#136	CREB3L1	17	17	34	694.719
#137	GTF2H3	17	11	28	953.764
#138	SUPT6H	17	13	30	1962.455
#139	MAFB	17	11	28	421.321
#140	KLF4	17	11	28	357.635
#141	TCF21	17	13	30	599.46
#142	KLF2	17	15	32	953.771
#143	TFDP2	16	15	31	1188.568
#144	RB1	16	12	28	1263.023
#145	NFYA	16	17	33	1566.973
#146	TBX2	16	18	34	1163.764
#147	POU2F3	16	9	25	689.593
#148	SOX21	16	14	30	805.196
#149	TSC22D3	16	14	30	809.339
#150	EGR1	16	11	27	368.232
#151	MEIS2	16	17	33	1223.99
#152	SLC2A4RG	16	13	29	1466.805
#153	FOSB	16	6	22	288.667
#154	ZNF91	16	13	29	1321.182
#155	CUX1	16	6	22	764.057
#156	BCL3	16	8	24	883.722
#157	ZHX2	16	14	30	1535.718
#158	GATA2	16	12	28	2238.799
#159	HOXD11	16	13	29	1041.249
#160	TP73	16	17	33	1956.808
#161	HR	15	15	30	2143.663
#162	KLF10	15	9	24	413.672
#163	HOXA11	15	13	28	1410.552
#164	MEOX1	15	15	30	1017.358
#165	ZNF323	15	13	28	1060.413
#166	PPARA	15	10	25	932.136
#167	RUNX1T1	15	16	31	1425.242
#168	E2F4	15	17	32	1995.682
#169	LEF1	15	15	30	1218.49
#170	ELK3	15	20	35	2842.79
#171	FOXL2	15	17	32	2384.311
#172	HOXA1	15	18	33	2755.442
#173	HINFP	15	15	30	1143.866
#174	C2orf3	15	12	27	1334.31
#175	MYT1L	15	16	31	1379.005
#176	ESRRG	15	16	31	2548.211
#177	SMAD5	15	13	28	1250.719
#178	ZNF446	14	12	26	816.117
#179	TFCP2L1	14	14	28	1195.935
#180	NFE2L3	14	14	28	1063.82
#181	CEBPD	14	16	30	1001.004
#182	FOXD1	14	14	28	468.296
#183	MAFG	14	11	25	366.557
#184	BLZF1	14	15	29	1300.274
#185	ESRRA	14	15	29	1612.154
#186	PPARD	14	17	31	2065.997
#187	TBX10	14	8	22	550.858
#188	AR	14	13	27	1742.117
#189	HSF4	14	9	23	481.492
#190	HLF	14	21	35	1397.782
#191	GRHL2	14	9	23	376.572
#192	STAT1	14	9	23	956.651
#193	HES1	14	14	28	1206.798
#194	MZF1	14	18	32	1012.481
#195	HOXB9	14	13	27	955.386
#196	NR4A1	14	6	20	441.862
#197	PAX6	14	20	34	903.804
#198	MYBL2	14	10	24	1097.416
#199	LZTS1	14	13	27	920.267
#200	NR2F1	14	15	29	1091.143
#201	OVOL1	14	14	28	1270.259
#202	HOXB8	14	13	27	1165.63
#203	NFKB2	14	15	29	767.254
#204	CREB5	14	17	31	1791.082
#205	NEUROD1	14	19	33	1538.754
#206	TCF3	14	11	25	994.299
#207	MTA2	14	11	25	1279.349
#208	MECOM	14	6	20	282.344
#209	CNOT8	14	16	30	1819.389
#210	PHF1	14	10	24	680.634
#211	OLIG2	14	11	25	1203.986
#212	NFATC4	14	15	29	2171.417
#213	HNF1B	14	13	27	1100.296
#214	MSX1	13	12	25	665.507
#215	HOXC5	13	12	25	859.009
#216	E2F8	13	11	24	970.834
#217	PRDM1	13	12	25	505.397
#218	NR0B1	13	11	24	829.152
#219	ZNF132	13	14	27	1028.253
#220	STAT2	13	15	28	813.686
#221	CEBPA	13	15	28	1065.724
#222	ZNF134	13	12	25	1193.363
#223	ATF3	13	7	20	967.277
#224	HOXD9	13	11	24	378.581
#225	ZFP36L2	13	14	27	609.219
#226	MYCN	13	21	34	1210.299
#227	NFIX	13	17	30	1746.202
#228	NKX3-2	13	12	25	682.545
#229	MAFF	13	13	26	543.421
#230	NFAT5	13	15	28	1063.073
#231	TRPS1	13	11	24	1195.504
#232	ZNF117	13	4	17	731.119
#233	ASCL1	13	20	33	1759.818
#234	HHEX	13	11	24	536.08
#235	STRN3	13	17	30	1275.023
#236	SCML1	13	10	23	859.805
#237	MYOD1	13	17	30	1300.756
#238	POU3F3	13	18	31	1423.486
#239	POU4F1	12	15	27	662.765
#240	NR2C1	12	13	25	510.205
#241	PRRX2	12	16	28	984.931
#242	HOXD3	12	14	26	1220.906
#243	CSRNP3	12	17	29	1292.061
#244	MAFK	12	21	33	1549.473
#245	ZNF174	12	19	31	880.655
#246	GABPB1	12	14	26	1098.704
#247	ATOH1	12	14	26	1072.821
#248	USF2	12	16	28	968.81
#249	TCF7	12	15	27	593.094
#250	SOX10	12	8	20	449.714
#251	SP1	12	10	22	911.092
#252	FOXD2	12	15	27	1378.85
#253	TBX1	12	16	28	911.406
#254	ETS2	12	16	28	526.86
#255	NPAS2	12	15	27	1329.501
#256	ARNT2	12	18	30	1079.032
#257	NR2E1	12	11	23	481.797
#258	FOXF2	12	15	27	850.624
#259	FOXG1	12	17	29	811.362
#260	POU3F1	12	13	25	338.845
#261	TP53	12	17	29	1480.198
#262	FUBP1	12	15	27	969.969
#263	PLSCR1	12	9	21	415.491
#264	SPDEF	12	17	29	1033.12
#265	FOXE3	11	14	25	1220.266
#266	PITX2	11	14	25	1630.094
#267	TSC22D2	11	17	28	1359.147
#268	PLAG1	11	16	27	1048.632
#269	ESRRB	11	11	22	407.795
#270	HOXA2	11	17	28	1180.587
#271	ZNF167	11	19	30	1789.741
#272	SMAD3	11	17	28	617.624
#273	NR4A3	11	7	18	422.696
#274	REST	11	16	27	794.427
#275	POU3F2	11	15	26	743.478
#276	PKNOX2	11	10	21	574.213
#277	ZNF154	11	15	26	1439.725
#278	TFAP2B	11	10	21	579.825
#279	HOXA4	11	7	18	538.152
#280	ZSCAN2	11	11	22	1073.72
#281	JUND	11	13	24	539.25
#282	ZNF155	11	13	24	1034.259
#283	RCAN1	11	16	27	2232.715
#284	DMRT1	11	18	29	1242.073
#285	ATF5	11	11	22	766.762
#286	NKX3-1	11	11	22	658.435
#287	MSX2	11	16	27	799.721
#288	SIX1	11	17	28	948.32
#289	SCRT1	11	9	20	1037.084
#290	HOXA7	11	14	25	769.15
#291	PBX1	11	22	33	1154.007
#292	ISL1	11	16	27	1108.544
#293	NR5A2	11	20	31	1066.732
#294	SRY	10	16	26	1264.789
#295	VENTX	10	10	20	567.126
#296	E2F5	10	14	24	445.643
#297	TAF1B	10	15	25	842.792
#298	TBX5	10	13	23	908.434
#299	TBX19	10	19	29	876.939
#300	HOXC10	10	17	27	955.368
#301	HOXB1	10	15	25	1405.822
#302	RERE	10	16	26	962.416
#303	EGR4	10	17	27	764.931
#304	ZNF202	10	11	21	556.478
#305	EMX1	10	15	25	682.095
#306	T	10	16	26	1077.84
#307	MYF6	10	14	24	1165.071
#308	GABPA	10	12	22	634.103
#309	GCM1	10	17	27	1133.337
#310	REL	10	11	21	533.623
#311	ZNF93	10	13	23	560.661
#312	NEUROG1	10	13	23	1059.754
#313	LHX2	10	21	31	1039.245
#314	TFAP4	10	16	26	1523.866
#315	ZNF75D	10	18	28	990.067
#316	MLLT10	10	15	25	886.145
#317	TSHZ2	10	17	27	932.259
#318	NR3C2	10	14	24	687.489
#319	BARX1	10	14	24	929.01
#320	SOX5	10	8	18	484.399
#321	ERG	10	19	29	837.248
#322	NPAS1	10	9	19	367.496
#323	TEF	10	20	30	984.63
#324	ZXDC	9	19	28	598.287
#325	FOXJ1	9	21	30	1015.102
#326	HMGA2	9	22	31	1469.23
#327	GSC2	9	14	23	835.999
#328	C11orf9	9	16	25	708.3
#329	ZNF3	9	17	26	1158.181
#330	POU2F2	9	17	26	506.198
#331	ELK1	9	11	20	779.525
#332	RORB	9	13	22	1234.589
#333	NR5A1	9	17	26	796.415
#334	HEY2	9	16	25	1106.42
#335	ONECUT2	9	13	22	1004.559
#336	SALL1	9	16	25	1170.827
#337	SMAD6	9	20	29	1448.724
#338	SATB2	9	14	23	800.652
#339	IRX4	9	19	28	1010.918
#340	MYT1	9	15	24	916.311
#341	ARID3A	9	11	20	582.489
#342	ETV4	9	18	27	1088.894
#343	NRL	9	16	25	720.959
#344	GBX2	9	20	29	1324.457
#345	ZNF444	9	17	26	864.337
#346	POU4F3	9	16	25	2046.618
#347	SMAD1	9	14	23	465.005
#348	NFX1	9	21	30	1195.679
#349	HOXB3	9	16	25	1459.594
#350	ZGPAT	9	12	21	618.292
#351	LHX1	9	12	21	543.132
#352	FOXO3	9	15	24	2397.285
#353	MXD1	9	23	32	893.605
#354	NR2E3	9	14	23	584.603
#355	ALX3	8	10	18	302.981
#356	RFXAP	8	15	23	423.789
#357	MNX1	8	22	30	760.622
#358	NR2F6	8	22	30	747.642
#359	ZIC3	8	16	24	858.093
#360	PPBPL2	8	14	22	836.936
#361	DLX6	8	14	22	569.853
#362	IKZF1	8	18	26	830.44
#363	NKX2-8	8	18	26	1176.09
#364	ZNF157	8	15	23	559.408
#365	SIX3	8	15	23	1075.741
#366	NR1H4	8	12	20	410.546
#367	HOXA9	8	14	22	559.888
#368	ATF6	8	19	27	1121.122
#369	RBPJL	8	12	20	712.506
#370	HNF1A	8	18	26	670.074
#371	ZIC1	8	24	32	931.428
#372	ZHX3	8	17	25	1417.618
#373	RUNX2	8	15	23	715.758
#374	EN2	8	13	21	510.074
#375	ZKSCAN1	8	13	21	632.964
#376	BACH1	8	16	24	1086.092
#377	SOX11	8	20	28	721.526
#378	ZBTB17	8	15	23	563.543
#379	ZSCAN12	8	14	22	562.31
#380	FOXB1	8	12	20	675.644
#381	SIM1	8	20	28	1108.5
#382	TAL1	8	21	29	839.288
#383	MYOG	8	14	22	541.635
#384	CSDA	8	15	23	785.489
#385	MEOX2	8	12	20	267.478
#386	HOXD10	8	8	16	549.314
#387	POU6F1	8	18	26	926.55
#388	ELF5	8	14	22	638.699
#389	E2F2	7	16	23	715.455
#390	ZNF643	7	13	20	396.88
#391	FOXH1	7	15	22	1246.985
#392	HNF4A	7	12	19	391.4
#393	PHOX2B	7	16	23	683.758
#394	POU6F2	7	16	23	640.09
#395	ZNF165	7	22	29	1333.67
#396	YY1	7	16	23	609.396
#397	ZNF135	7	22	29	1152.191
#398	MLL	7	13	20	581.967
#399	CREBBP	7	15	22	654.722
#400	ZNF80	7	18	25	1167.874
#401	HIC1	7	23	30	608.794
#402	TLX2	7	19	26	934.78
#403	ELF4	7	17	24	555.074
#404	TCF12	7	16	23	604.594
#405	CREBZF	7	13	20	837.621
#406	SIM2	7	15	22	534.065
#407	PGR	7	17	24	784.479
#408	MAF	7	21	28	866.103
#409	GATA4	7	22	29	1228.201
#410	TCF15	7	20	27	1284.911
#411	LHX5	7	15	22	796.662
#412	CITED1	7	13	20	848.265
#413	ZNF639	7	17	24	594.159
#414	TAF4	7	13	20	730.247
#415	ONECUT1	7	17	24	672.594
#416	SOX18	7	15	22	825.742
#417	ELF2	7	16	23	952.557
#418	PAX4	7	15	22	584.365
#419	ZFP37	7	17	24	428.379
#420	FOXD3	6	13	19	765.386
#421	BATF3	6	15	21	441.308
#422	IRF4	6	14	20	1625.898
#423	LHX6	6	15	21	609.092
#424	CUX2	6	14	20	1027.193
#425	CBL	6	12	18	562.311
#426	PHOX2A	6	9	15	360.792
#427	ASCL2	6	13	19	600.982
#428	ZNF236	6	17	23	512.419
#429	PDX1	6	17	23	548.582
#430	RUNX1	6	22	28	772.69
#431	HOXB7	6	25	31	1296.752
#432	VDR	6	19	25	605.993
#433	TBX6	6	17	23	803.391
#434	WT1	6	15	21	1042.481
#435	CTBP1	6	14	20	404.047
#436	FOXO1	6	20	26	592.337
#437	IRX5	6	20	26	737.519
#438	NR6A1	6	12	18	644.433
#439	KLF12	6	14	20	465.99
#440	HOXD13	6	21	27	673.632
#441	PRDM2	6	13	19	529.498
#442	PKNOX1	6	17	23	579.736
#443	ETV2	6	14	20	479.96
#444	HESX1	5	12	17	748.625
#445	NFE2	5	18	23	486.404
#446	ZSCAN18	5	11	16	916.918
#447	ESR1	5	17	22	627.46
#448	RARA	5	16	21	737.186
#449	HIF3A	5	16	21	417.215
#450	PAX5	5	18	23	733.623
#451	CEBPE	5	16	21	1088.973
#452	SOX30	5	14	19	398.686
#453	PPARG	5	24	29	424.138
#454	PAX7	5	15	20	298.995
#455	TCF7L2	5	20	25	402.89
#456	FOXP3	5	17	22	452.937
#457	ESR2	5	21	26	665.778
#458	MBD1	5	23	28	563.75
#459	ZFP36L1	5	15	20	466.906
#460	NR1I2	5	15	20	619.46
#461	GATA3	5	20	25	810.199
#462	PTH	5	16	21	510.039
#463	HMG20B	4	12	16	533.682
#464	PAX3	4	15	19	272.618
#465	MYF5	4	20	24	503.376
#466	FOXO4	4	17	21	594.405
#467	ZNF41	4	19	23	598.125
#468	TLX3	4	14	18	396.17
#469	MSRB2	4	15	19	383.155
#470	TADA2A	4	18	22	551.776
#471	HOXD1	4	17	21	555.166
#472	TAF12	4	15	19	475.572
#473	HMX1	4	16	20	515.946
#474	TBX4	4	17	21	472.76
#475	CREM	4	13	17	496.035
#476	BRD8	4	14	18	648.293
#477	HOXC13	4	16	20	354.275
#478	SNAPC5	4	18	22	1143.209
#479	PAX8	4	16	20	679.106
#480	KDM5B	4	18	22	490.375
#481	IKZF3	4	11	15	225.056
#482	FOXC2	4	14	18	307.044
#483	SLC26A3	3	15	18	436.124
#484	NFATC1	3	16	19	345.334
#485	IRF5	3	20	23	336.516
#486	HOXC8	3	20	23	531.643
#487	HOXA3	3	17	20	375.297
#488	HNF4G	3	16	19	500.556
#489	HAND2	3	12	15	168.96
#490	ATF6B	3	16	19	381.511
#491	ELK4	3	13	16	296.187
#492	NKX2-5	2	18	20	213.997
#493	POU1F1	2	23	25	219.091
#494	THRA	2	17	19	278.834
#495	CDKN2A	2	18	20	171.521
#496	TAF13	2	24	26	357.546
#497	ZNF287	2	17	19	269.03
#498	SCAND2	2	14	16	653.612
#499	RARB	2	16	18	369.934
#500	ZNF81	0	21	21	0