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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF207	57	3	60	223.594
#2	ETV5	55	7	62	1157.169
#3	GABPA	51	8	59	1949.216
#4	MEF2C	48	1	49	34.827
#5	EBF1	47	5	52	2210.698
#6	MBD1	41	6	47	766.837
#7	IKZF1	40	9	49	752.071
#8	STRN3	39	3	42	124.139
#9	ASCL2	38	7	45	3717.536
#10	FOXO1	37	6	43	828.414
#11	FOSL2	37	6	43	1600.406
#12	GLIS2	36	6	42	164.084
#13	MAFB	35	6	41	500.566
#14	ETS2	34	6	40	2314.896
#15	ZBTB38	34	2	36	336.998
#16	SATB2	33	4	37	305.342
#17	ZBTB48	33	7	40	3171.343
#18	AEBP1	33	1	34	30.083
#19	HHEX	32	7	39	1211.936
#20	TSHZ3	32	11	43	1425.655
#21	TWIST1	32	3	35	291.075
#22	CDX2	31	5	36	1671.816
#23	MMP14	31	10	41	703.173
#24	CREM	31	13	44	2086.081
#25	CEBPA	30	6	36	1167.257
#26	HOPX	30	4	34	218.904
#27	MTA2	30	4	34	415.012
#28	ETV1	30	9	39	522.623
#29	ERG	29	8	37	522.515
#30	ISX	29	9	38	709.465
#31	HOXB2	29	16	45	1651.524
#32	NFIB	29	13	42	1761.6
#33	USF1	28	7	35	567.59
#34	HIC1	27	14	41	668.809
#35	C11orf9	27	8	35	421.99
#36	PRRX1	26	7	33	190.708
#37	TFCP2L1	26	13	39	601.026
#38	BCL6	26	12	38	858.211
#39	ZEB1	26	9	35	287.764
#40	ZIC5	25	12	37	891.412
#41	MLL	25	8	33	939.88
#42	FOXQ1	25	13	38	2184.917
#43	TCF3	25	8	33	1131.643
#44	STAT1	25	10	35	380.971
#45	RB1	24	11	35	1674.274
#46	NR3C1	24	15	39	1107.819
#47	ZNF75D	24	14	38	1835.118
#48	HNF4A	24	14	38	1901.641
#49	ZRANB2	24	12	36	1638.712
#50	CTNNB1	24	9	33	630.535
#51	NR4A2	24	12	36	1713.105
#52	MEIS2	24	12	36	1451.96
#53	SPDEF	23	14	37	1503.165
#54	HOXB1	23	7	30	501.043
#55	BHLHE40	22	12	34	1124.838
#56	PROX1	22	12	34	624.507
#57	ZNF197	22	13	35	1032.342
#58	FOXS1	22	12	34	1455.253
#59	MXD1	22	12	34	1420.755
#60	ZNF268	22	10	32	1490.477
#61	HES6	22	11	33	2032.017
#62	NR2E3	22	18	40	1699.651
#63	MEOX1	22	11	33	712.73
#64	EGR1	22	10	32	1107.293
#65	ZNF238	22	9	31	1245.942
#66	DLX1	21	19	40	1488.199
#67	ZIC2	21	10	31	838.71
#68	CREB3L1	21	5	26	115.659
#69	OVOL1	21	11	32	1667.8
#70	CBL	21	12	33	1587.755
#71	NFATC3	21	3	24	228.861
#72	TRERF1	21	13	34	2217.778
#73	SATB1	21	13	34	2212.249
#74	VAV1	21	17	38	1683.67
#75	TFAP2A	21	15	36	634.238
#76	TAL1	20	15	35	1330.763
#77	CREBBP	20	16	36	2034.534
#78	TCF4	20	9	29	1281.24
#79	TRIM22	20	8	28	178.438
#80	EGR2	20	13	33	1036.877
#81	PHF1	20	10	30	1058.772
#82	SP140	19	8	27	3225.122
#83	HNF4G	19	14	33	1319.046
#84	CDKN2A	19	12	31	1306.565
#85	HOXA5	19	3	22	794.16
#86	SOX8	19	8	27	570.656
#87	HMGA2	19	9	28	1608.336
#88	ATF3	19	6	25	756.42
#89	EN2	18	14	32	2733.708
#90	KLF4	18	7	25	717.109
#91	NR2F6	18	15	33	1922.44
#92	ARNT	18	11	29	782.23
#93	FOXK2	18	11	29	780.491
#94	NFAT5	18	15	33	2373.324
#95	MZF1	18	11	29	1632.833
#96	HOXA9	18	8	26	465.719
#97	STAT5B	18	8	26	276.31
#98	MESP2	18	11	29	2070.834
#99	NOTCH1	18	11	29	2143.946
#100	ELF5	18	16	34	1353.82
#101	ZNF24	18	11	29	1085.846
#102	ZNF397	17	13	30	950.98
#103	TFE3	17	16	33	1121.184
#104	EGR3	17	14	31	841.748
#105	TP63	17	10	27	1445.337
#106	ATF7	17	9	26	2000.557
#107	MEF2D	17	7	24	1542.258
#108	LZTS1	17	15	32	1789.816
#109	HOXA10	17	7	24	777.751
#110	ALX3	17	12	29	1299.509
#111	HOXA13	17	10	27	966.646
#112	WT1	17	12	29	2052.834
#113	CBFA2T3	17	10	27	1173.579
#114	SPIB	17	9	26	1285.447
#115	GLIS3	17	15	32	1670.291
#116	TBX1	16	14	30	990.151
#117	E2F2	16	16	32	1661.036
#118	TP53	16	11	27	839.049
#119	SOX11	16	10	26	511.763
#120	FOSB	16	8	24	649.297
#121	ETV6	16	11	27	552.683
#122	ETS1	16	10	26	607.793
#123	FOXJ2	16	11	27	1230.069
#124	TFAP4	16	14	30	1767.331
#125	HOXD9	16	13	29	1127.459
#126	FOXL1	16	8	24	1278.776
#127	FOS	16	4	20	172.352
#128	HSF1	16	10	26	1077.334
#129	HOXA3	16	4	20	226.492
#130	PLAG1	16	17	33	827.422
#131	CREB5	15	13	28	1360.191
#132	MEIS1	15	15	30	626.492
#133	SLC26A3	15	17	32	1025.193
#134	HOXD11	15	7	22	652.286
#135	NKX2-8	15	14	29	1846.248
#136	C2orf3	15	11	26	2071.217
#137	NPAS2	15	18	33	1298.63
#138	RUNX1T1	15	14	29	1438.039
#139	PPARA	15	14	29	1617.659
#140	ATOH1	15	10	25	1755.867
#141	C12orf28	15	14	29	622.955
#142	WNT5A	15	15	30	1011.699
#143	DLX3	14	16	30	1147.318
#144	POU3F1	14	12	26	1206.94
#145	NR2F1	14	12	26	583.938
#146	HOXB13	14	19	33	1852.053
#147	IRX3	14	12	26	452.547
#148	NR4A3	14	18	32	1144.303
#149	HOXA2	14	10	24	676.795
#150	FOXC1	14	12	26	789.772
#151	ZSCAN18	14	13	27	1579.236
#152	BACH1	14	14	28	1023.696
#153	FOXP3	14	14	28	1752.856
#154	FOXN4	14	13	27	1059.146
#155	HOXA7	14	7	21	793.599
#156	NKX2-5	14	10	24	1373.58
#157	ETV7	14	13	27	1005.407
#158	ARNT2	14	17	31	1667.55
#159	ZNF45	14	12	26	1557.69
#160	CREBZF	14	14	28	1182.296
#161	RCAN1	14	13	27	902.405
#162	CEBPD	14	17	31	2202.078
#163	SCAND1	14	15	29	1128.974
#164	HOXC11	13	14	27	805.777
#165	ELK1	13	11	24	913.75
#166	SMAD3	13	16	29	1583.063
#167	VAX2	13	11	24	1246.747
#168	HSF5	13	13	26	1367.87
#169	REST	13	11	24	1324.084
#170	SREBF1	13	10	23	286.696
#171	SOX7	13	18	31	1292.249
#172	ATF6B	13	12	25	1383.915
#173	PITX2	13	10	23	728.796
#174	MLX	13	11	24	962.559
#175	NFIC	13	17	30	1070.396
#176	SMAD9	13	15	28	1513.848
#177	MLLT10	13	14	27	920.267
#178	RFXAP	13	12	25	1111.17
#179	ZNF446	13	12	25	1164.268
#180	ZNF134	13	11	24	956.098
#181	HOXA11	13	18	31	1299.675
#182	CITED1	13	12	25	445.989
#183	ZNF117	13	10	23	907.393
#184	NANOG	13	14	27	1296.417
#185	ERF	13	19	32	2023.679
#186	LEF1	13	14	27	1249.036
#187	ZNF157	13	14	27	1612.254
#188	RARA	13	10	23	683.575
#189	EMX1	13	12	25	727.732
#190	NFATC4	13	12	25	1136.645
#191	NEUROG1	12	12	24	960.697
#192	TRPS1	12	15	27	1383.091
#193	FOXD1	12	11	23	181.632
#194	PBX1	12	14	26	837.607
#195	NR3C2	12	13	25	832.696
#196	SIX4	12	13	25	1622.855
#197	SP3	12	14	26	899.266
#198	FOXL2	12	16	28	1469.729
#199	SNAPC5	12	13	25	868.66
#200	NPAT	12	11	23	653.978
#201	SOX4	12	11	23	709.883
#202	HOXD10	12	14	26	923.545
#203	NR6A1	12	9	21	929.003
#204	SIX1	12	15	27	1021.01
#205	TBR1	12	11	23	1294.594
#206	NR1I2	12	17	29	1015.583
#207	HES5	12	11	23	1053.408
#208	RORC	12	17	29	1235.737
#209	NR2E1	12	13	25	1109.843
#210	SIX2	12	12	24	1408.747
#211	RXRB	12	14	26	1234.576
#212	ETV4	12	15	27	1346.308
#213	HEY1	12	12	24	993.082
#214	ZNF41	12	11	23	1084.575
#215	NPAS1	12	11	23	1183.213
#216	ZNF287	12	11	23	1062.859
#217	HOXD13	12	14	26	793.79
#218	KLF12	12	11	23	1156.116
#219	MESP1	12	12	24	624.432
#220	HOXA1	12	13	25	766.137
#221	SOX13	12	15	27	810.169
#222	CSDA	12	14	26	1181.548
#223	NFE2	12	9	21	546.768
#224	SPI1	12	15	27	915.552
#225	HOXD4	11	11	22	688.41
#226	NFATC2	11	12	23	836.789
#227	TBX5	11	18	29	1938.315
#228	NFIX	11	14	25	1407.966
#229	ONECUT1	11	11	22	829.796
#230	ALS2CR8	11	11	22	803.902
#231	NR5A1	11	14	25	1068.329
#232	TP73	11	15	26	1070.196
#233	ZNF85	11	17	28	1640.984
#234	IRX4	11	11	22	980.529
#235	FOXA1	11	17	28	1115.665
#236	HCFC1	11	10	21	542.817
#237	PAX4	11	14	25	1364.627
#238	SMAD2	11	14	25	982.493
#239	RORA	11	14	25	1664.415
#240	KLF15	11	15	26	1159.591
#241	NOBOX	11	12	23	616.388
#242	ZFPM2	11	14	25	388.987
#243	LMO4	11	17	28	1203.314
#244	RXRG	11	16	27	1387.804
#245	NR1I3	11	9	20	741.098
#246	ZNF81	11	14	25	882.901
#247	TFAP2C	11	11	22	2146.277
#248	SOX18	11	16	27	815.863
#249	NFYA	11	12	23	694.386
#250	FOXA2	11	15	26	2918.27
#251	VTN	11	16	27	1868.753
#252	FOXI1	11	14	25	955.25
#253	ZSCAN10	11	16	27	1250.183
#254	CTBP1	11	9	20	1476.803
#255	ZSCAN23	11	13	24	1110.519
#256	FOXR2	11	13	24	1491.134
#257	MSX2	10	19	29	1729.234
#258	TBX15	10	15	25	1094.3
#259	FOXE3	10	13	23	884.792
#260	SEBOX	10	14	24	1282.412
#261	ANKRD30A	10	16	26	1304.101
#262	TCF21	10	12	22	718.718
#263	NFATC1	10	17	27	978.367
#264	SOX17	10	16	26	997.707
#265	TFEC	10	15	25	906.19
#266	IRX2	10	18	28	1812.974
#267	CRX	10	14	24	1118.445
#268	SP4	10	10	20	586.059
#269	KLF9	10	15	25	694.972
#270	ZSCAN2	10	15	25	1205.167
#271	HOXC9	10	14	24	1015.5
#272	ASCL1	10	16	26	1428.683
#273	FOXO3	10	16	26	879.576
#274	NR0B1	10	11	21	1660.009
#275	IRX5	10	17	27	1135.778
#276	MEIS3	10	13	23	1440.643
#277	ZIC1	10	15	25	1427.709
#278	RUNX3	10	15	25	615.024
#279	NFKB2	10	11	21	869.568
#280	POU6F1	10	16	26	1134.209
#281	KLF2	10	15	25	1447.373
#282	CUX2	10	14	24	1032.545
#283	SIM1	10	12	22	970.971
#284	TADA3	10	11	21	1247.186
#285	SLC2A4RG	10	12	22	2246.916
#286	ZFHX3	10	13	23	713.11
#287	ZFP36L1	10	14	24	1485.03
#288	TULP4	10	21	31	1674.376
#289	HESX1	10	11	21	961.804
#290	FOXH1	10	13	23	1225.429
#291	NFIA	10	16	26	1467.768
#292	POU6F2	10	20	30	1930.081
#293	ZNF132	10	14	24	998.008
#294	TAF4	10	12	22	1037.576
#295	POU1F1	10	11	21	1195.959
#296	ZSCAN1	10	9	19	727.932
#297	NR5A2	10	12	22	523.344
#298	NKX6-2	9	17	26	1802.887
#299	ZNF131	9	14	23	1168.281
#300	MECOM	9	15	24	912.289
#301	VSX1	9	13	22	922.84
#302	BRD8	9	16	25	1227.609
#303	POU5F2	9	13	22	970.063
#304	ZNF90	9	11	20	1352.304
#305	KLF1	9	16	25	1339.288
#306	ZSCAN20	9	13	22	1576.305
#307	TLX3	9	9	18	870.697
#308	NKX2-3	9	12	21	361.872
#309	HR	9	17	26	1522.965
#310	ZFHX4	9	16	25	740.013
#311	SIM2	9	13	22	1456.442
#312	FOXJ1	9	16	25	953.599
#313	HLF	9	12	21	836.883
#314	GATA3	9	12	21	568.701
#315	PITX1	9	13	22	805.474
#316	ZNF92	9	12	21	945.929
#317	GATA4	9	15	24	600.576
#318	ESR2	9	19	28	1336.542
#319	IKZF3	9	12	21	803.704
#320	POU2F1	9	15	24	1301.031
#321	MYF6	9	12	21	585.059
#322	GAS7	9	14	23	827.045
#323	GRHL3	9	18	27	1074.12
#324	EGR4	9	14	23	1042.767
#325	IRX1	9	16	25	1200.79
#326	GATAD1	9	12	21	715.581
#327	PGBD1	8	12	20	2669.198
#328	THRB	8	20	28	798.903
#329	ARX	8	14	22	608.074
#330	ISL1	8	17	25	1135.006
#331	NR1H4	8	17	25	1320.394
#332	TEAD2	8	12	20	646.692
#333	ISL2	8	13	21	1482.623
#334	MYCN	8	16	24	1372.841
#335	HOXB8	8	7	15	434.593
#336	KCNH8	8	14	22	526.74
#337	TBX2	8	14	22	618.063
#338	GLI2	8	16	24	932.225
#339	YY1	8	16	24	664.155
#340	LMX1A	8	16	24	1138.692
#341	SOX5	8	19	27	881.185
#342	HOXB6	8	8	16	223.572
#343	MYNN	8	19	27	1144.254
#344	SMAD6	8	16	24	714.259
#345	FOXC2	8	16	24	1047.202
#346	POU3F2	8	17	25	1100.711
#347	KDM5A	8	16	24	816.336
#348	ESX1	8	17	25	1245.767
#349	RERE	8	15	23	1100.939
#350	SOX30	8	12	20	1124.183
#351	ZNF71	8	14	22	738.103
#352	GATA5	8	11	19	730.053
#353	RORB	8	12	20	760.359
#354	KDM5B	8	8	16	591.118
#355	ZIC3	8	19	27	1115.122
#356	ATF2	8	14	22	770.211
#357	BNC1	8	17	25	1263.97
#358	POU3F4	8	15	23	996.255
#359	SALL1	8	16	24	1001.048
#360	ZNF154	8	12	20	742.809
#361	ZXDC	8	11	19	457.925
#362	PKNOX1	8	13	21	751.948
#363	MEOX2	8	10	18	738.711
#364	THRA	8	16	24	1118.052
#365	TFAP2D	8	13	21	864.454
#366	RARG	8	15	23	822.917
#367	TSC22D2	8	13	21	1478.836
#368	RFX3	8	16	24	904.866
#369	HMG20B	8	18	26	1089.302
#370	TSC22D3	8	17	25	950.103
#371	GATA1	8	18	26	808.792
#372	RBPJL	8	11	19	1230.957
#373	TCF20	8	10	18	676.649
#374	FOXK1	7	16	23	674.615
#375	PAX6	7	18	25	720.651
#376	RARB	7	14	21	274.559
#377	ZNF83	7	13	20	293.182
#378	TWIST2	7	13	20	1239.073
#379	HOXA4	7	11	18	492.793
#380	PBX3	7	14	21	862.122
#381	BCL11B	7	19	26	788.263
#382	ZSCAN4	7	12	19	898.732
#383	PGR	7	10	17	521.315
#384	VENTX	7	18	25	875.654
#385	FOXG1	7	12	19	618.243
#386	DMRT2	7	15	22	642.906
#387	ST18	7	17	24	1128.225
#388	DBP	7	18	25	1409.176
#389	GCM1	7	15	22	666.259
#390	CREB3L3	7	12	19	696.06
#391	ONECUT3	7	13	20	983.71
#392	REL	7	15	22	503.465
#393	POU2F2	7	21	28	889.922
#394	SNAI3	7	11	18	569.578
#395	PAX3	7	14	21	914.245
#396	TAF13	7	12	19	804.92
#397	L3MBTL4	7	20	27	1224.135
#398	ZFP37	7	12	19	754.292
#399	ZNF93	7	14	21	778.436
#400	ELK4	7	16	23	733.141
#401	PLSCR1	7	13	20	554.254
#402	SOX10	7	17	24	1202.047
#403	FOXP2	7	16	23	752.746
#404	DLX4	7	12	19	936.038
#405	LHX9	7	12	19	674.484
#406	PAX8	7	12	19	676.538
#407	ESRRB	7	11	18	389.826
#408	FOXE1	7	11	18	537.054
#409	FUBP1	7	18	25	764.576
#410	NEUROD1	7	14	21	439.473
#411	ZNF256	6	13	19	580.52
#412	MIXL1	6	11	17	348.776
#413	ZNF483	6	11	17	1120.703
#414	ZEB2	6	12	18	319.813
#415	MYT1L	6	9	15	358.458
#416	ZNF80	6	13	19	1045.252
#417	DLX6	6	12	18	1023.495
#418	SOX21	6	10	16	421.967
#419	POU2F3	6	16	22	567.395
#420	SMAD4	6	16	22	720.657
#421	BLZF1	6	19	25	746.132
#422	DMRT1	6	11	17	525.58
#423	HIF3A	6	14	20	894.771
#424	MYF5	6	18	24	1016.836
#425	ZNF639	6	16	22	871.209
#426	PAX7	6	16	22	848.981
#427	HDX	6	12	18	756.995
#428	PKNOX2	6	16	22	972.687
#429	TBX3	6	11	17	670.967
#430	TLX1	6	12	18	576.887
#431	SPIC	6	14	20	888.156
#432	ZNF70	6	12	18	537.947
#433	ZNF496	6	16	22	1488.166
#434	ZNF135	6	15	21	1094.964
#435	TBX6	6	16	22	703.399
#436	MGA	6	13	19	425.226
#437	POU4F2	6	14	20	771.935
#438	SIN3A	6	15	21	850.658
#439	BARX1	6	12	18	1190.269
#440	DLX2	6	14	20	438.788
#441	GSX2	6	15	21	605.802
#442	PHOX2B	5	13	18	607.519
#443	PDX1	5	19	24	1112.539
#444	OLIG2	5	11	16	360.064
#445	ESR1	5	15	20	696.546
#446	TRIM29	5	16	21	397.306
#447	MYT1	5	13	18	605.569
#448	FOXN3	5	13	18	485.166
#449	NEUROD2	5	16	21	718.943
#450	FOXD3	5	9	14	210.47
#451	MITF	5	16	21	688.576
#452	AFF4	5	18	23	731.264
#453	NKX2-1	5	18	23	490.889
#454	ZNF434	5	12	17	437.34
#455	JUND	5	16	21	570.348
#456	HOXD3	5	14	19	661.206
#457	KLF17	5	15	20	975.164
#458	PCGF2	5	11	16	436.391
#459	ONECUT2	5	17	22	1503.615
#460	SOX1	5	17	22	656.415
#461	TSHZ2	5	15	20	526.282
#462	HNF1B	5	15	20	439.65
#463	CSRNP3	5	13	18	474.29
#464	ZFP42	5	12	17	551.075
#465	ZNF167	5	18	23	1462.2
#466	HOXD1	5	9	14	723.482
#467	RUNX1	4	16	20	425.231
#468	TEF	4	13	17	618.403
#469	LHX2	4	15	19	580.069
#470	ZFHX2	4	10	14	278.039
#471	ZSCAN12	4	18	22	408.109
#472	ZKSCAN3	4	13	17	313.662
#473	ZNF396	4	14	18	334.877
#474	SOX6	4	13	17	796.581
#475	GATAD2A	4	12	16	668.891
#476	PRDM2	4	15	19	672.074
#477	PTH	4	16	20	471.777
#478	BHLHE41	4	17	21	290.243
#479	TFAP2B	4	11	15	570.406
#480	ZNF175	4	15	19	581.01
#481	TFDP3	4	12	16	342.183
#482	SCAND2	4	17	21	431.188
#483	NRL	4	14	18	536.39
#484	HIRA	4	17	21	547.09
#485	MAF	4	14	18	386.405
#486	ZNF3	4	12	16	293.589
#487	FLI1	4	14	18	592.521
#488	ESRRG	4	18	22	422.295
#489	TBX20	3	19	22	577.874
#490	POU4F1	3	17	20	451.056
#491	ZNF215	3	14	17	586.387
#492	HEY2	3	16	19	280.626
#493	GSX1	3	8	11	193.479
#494	PEG3	3	12	15	285.442
#495	SCAND3	3	12	15	228.884
#496	MKX	2	13	15	172.844
#497	PPARD	2	13	15	264.807
#498	RUNX2	2	11	13	72.279
#499	SOX2	2	20	22	219.245
#500	SIX3	1	12	13	38.868