Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TGIF1	75	2	77	1322.727
#2	HLF	74	4	78	1044.426
#3	ZNF217	67	2	69	307.107
#4	YBX1	62	6	68	476.623
#5	ELK3	56	3	59	266.74
#6	E2F7	53	3	56	231.416
#7	MYT1L	53	2	55	82.314
#8	CSDA	52	10	62	807.911
#9	ELF4	51	7	58	1170.974
#10	THRB	49	5	54	1518.235
#11	SATB1	46	7	53	334.045
#12	PEG3	44	9	53	4889.343
#13	SOX4	41	8	49	355.687
#14	TBR1	41	9	50	297.468
#15	UHRF1	40	8	48	3596.996
#16	ASCL1	38	10	48	8288.194
#17	E2F5	38	9	47	573.469
#18	MEF2C	37	4	41	47.163
#19	TP53	37	10	47	722.618
#20	SOX8	37	7	44	3804.345
#21	NEUROD2	37	3	40	52.401
#22	CUX2	35	4	39	7272.951
#23	FOXM1	35	4	39	112.412
#24	MMP14	35	8	43	168.913
#25	MSRB2	35	6	41	1378.736
#26	SOX2	34	10	44	853.505
#27	GAS7	34	11	45	3499.21
#28	FOSL2	34	8	42	419.368
#29	MYT1	34	9	43	1291.118
#30	SOX11	33	7	40	718.189
#31	LMO4	33	8	41	139.347
#32	ZFP36L2	33	7	40	263.399
#33	KLF6	32	11	43	493.44
#34	THRA	32	14	46	2647.315
#35	FOXC1	32	14	46	7129.894
#36	NR2E1	32	12	44	5763.396
#37	MEOX2	32	13	45	1711.021
#38	CBL	32	3	35	653.082
#39	LHX6	32	7	39	160.687
#40	C1orf85	31	9	40	14076.784
#41	CEBPD	31	4	35	49.617
#42	HOXA3	31	4	35	90.267
#43	KCNH8	30	11	41	675.6
#44	BHLHE40	30	14	44	8039.954
#45	SUPT6H	30	7	37	491.595
#46	GABPA	30	7	37	805.373
#47	ZNF367	30	6	36	556.848
#48	ZEB1	30	8	38	488.625
#49	GLIS3	30	10	40	1930.799
#50	FBXW7	30	5	35	272.853
#51	NR3C2	29	8	37	8463.845
#52	MYC	29	9	38	915.489
#53	TEAD3	29	9	38	428.016
#54	SOX6	29	10	39	696.792
#55	IRF7	28	12	40	258.938
#56	PROX1	27	8	35	1408.017
#57	ARNTL	27	12	39	5100.755
#58	SP1	27	11	38	1000.182
#59	SOX1	27	11	38	944.492
#60	ZNF238	26	18	44	6419.019
#61	SIX1	26	8	34	667.128
#62	ARX	26	11	37	1643.976
#63	HOXA5	26	3	29	439.427
#64	TEAD4	26	9	35	1021.757
#65	STAT1	26	3	29	698.16
#66	TRIM22	26	7	33	553.709
#67	HEY1	25	9	34	4174.212
#68	RUNX1	25	11	36	259.302
#69	PAX6	25	11	36	1707.055
#70	ETV1	24	9	33	688.073
#71	FOXO1	24	10	34	591.745
#72	ATF5	24	17	41	1308.253
#73	LHX2	24	17	41	15615.547
#74	SATB2	24	11	35	3287.184
#75	BCL6	24	11	35	167.332
#76	SCRT1	23	8	31	77.063
#77	HOXB3	23	9	32	588.956
#78	TCF3	23	13	36	353.437
#79	BCL3	23	7	30	891.184
#80	TAF12	23	13	36	4566.936
#81	SALL1	23	18	41	6204.484
#82	MYBL2	23	9	32	631.21
#83	HOXC10	23	6	29	1558.016
#84	WNT5A	22	13	35	404.133
#85	SMAD5	22	3	25	679.566
#86	TFDP2	22	16	38	1747.573
#87	HES6	22	13	35	546.735
#88	OLIG2	22	11	33	2501.091
#89	BCL11B	22	9	31	139.943
#90	HCLS1	22	5	27	331.192
#91	NKX3-2	22	20	42	1619.649
#92	HOXA10	21	13	34	2174.171
#93	SOX9	21	15	36	1676.235
#94	HOXD9	21	12	33	733.138
#95	LZTS1	21	12	33	1536.064
#96	EN2	21	11	32	1187.982
#97	FOXD1	21	10	31	972.07
#98	VAV1	21	10	31	284.659
#99	HOXA11	21	8	29	1053.998
#100	STAT5B	21	10	31	183.095
#101	HES5	21	12	33	484.669
#102	ETS1	20	12	32	527.176
#103	EN1	20	15	35	1207.003
#104	ZNF75D	20	15	35	5101.929
#105	HOXA7	20	9	29	250.973
#106	ATF3	20	9	29	223.255
#107	ST18	20	15	35	1101.626
#108	C11orf9	20	7	27	525.316
#109	E2F8	20	6	26	651.922
#110	MECOM	19	16	35	1412.067
#111	HOXD10	19	12	31	496.162
#112	AEBP1	19	15	34	1252.044
#113	NOTCH1	19	14	33	1865.081
#114	NEUROD1	19	13	32	3710.879
#115	PRRX1	19	8	27	179.521
#116	NR0B1	19	12	31	1287.753
#117	TRIM25	19	12	31	1607.062
#118	HOXB9	19	16	35	490.495
#119	RXRB	19	13	32	2966.683
#120	KLF12	19	10	29	283.742
#121	KLF5	18	15	33	2047.94
#122	NFATC2	18	17	35	1283.238
#123	TBX2	18	15	33	910.654
#124	KLF4	18	8	26	613.959
#125	HEY2	18	13	31	948.592
#126	HES1	18	11	29	852.209
#127	HNF4G	18	13	31	784.247
#128	NFAT5	18	11	29	4695.057
#129	TLX3	17	16	33	4187.122
#130	ZNF117	17	13	30	1607.889
#131	SNAI2	17	15	32	1443.151
#132	NFIX	17	9	26	4386.112
#133	FOSL1	17	15	32	1972.712
#134	ZFPM2	17	14	31	511.89
#135	SLC2A4RG	17	17	34	1337.728
#136	POU3F3	17	20	37	4474.058
#137	MEIS1	17	16	33	1254.299
#138	SMAD3	17	14	31	2059.648
#139	ZNF167	17	13	30	331.385
#140	MAFB	17	13	30	2693.245
#141	CITED1	17	14	31	1071.011
#142	JUN	17	15	32	3198.384
#143	ZIC3	16	12	28	4531.001
#144	DLX6	16	11	27	383.787
#145	IRX1	16	14	30	3788.786
#146	SOX10	16	8	24	728.593
#147	NR4A2	16	16	32	1014.552
#148	NFE2L2	16	14	30	474.959
#149	EMX1	16	6	22	388.019
#150	DLX1	16	12	28	4803.272
#151	MAFG	16	11	27	3080.246
#152	ZIC2	16	16	32	6215.965
#153	HOXA13	15	11	26	311.784
#154	FOXI1	15	11	26	350.412
#155	TEAD2	15	10	25	3522.353
#156	SPEN	15	12	27	1081.774
#157	NKX2-5	15	12	27	4018.375
#158	IRX2	15	15	30	1151.151
#159	E2F1	15	9	24	610.788
#160	SMAD9	15	11	26	427.257
#161	SIX5	15	11	26	1197.045
#162	LASS5	15	15	30	367.699
#163	HMX1	15	10	25	2868.396
#164	MKX	15	12	27	1019.188
#165	GABPB1	15	10	25	301.27
#166	ARNT	15	16	31	3218.326
#167	FOXG1	14	21	35	11777.981
#168	TFAP2A	14	15	29	9308.923
#169	FOS	14	3	17	154.089
#170	FUBP1	14	14	28	1538.942
#171	NR2F2	14	14	28	557.665
#172	HESX1	14	12	26	540.359
#173	FOXJ1	14	12	26	275.663
#174	SOX15	14	15	29	1164.161
#175	HOXC13	14	11	25	1421.01
#176	TFEC	14	8	22	1001.545
#177	IRF1	14	12	26	321.038
#178	ATF2	14	20	34	1947.353
#179	EGR4	14	11	25	103.761
#180	HOXC9	14	10	24	2409.27
#181	HOXD11	14	13	27	398.25
#182	HOXD3	14	8	22	694.629
#183	ZXDC	14	14	28	1755.699
#184	TCFL5	14	12	26	6796.617
#185	EGR2	14	5	19	432.107
#186	SPI1	14	11	25	668.516
#187	HIC1	13	12	25	439.967
#188	MYCN	13	11	24	249.487
#189	PKNOX1	13	16	29	1759.747
#190	HIF3A	13	19	32	2115.419
#191	ALX3	13	17	30	3340.222
#192	PKNOX2	13	10	23	515.364
#193	NFATC4	13	15	28	1213.733
#194	ISX	13	12	25	1650.636
#195	MNX1	13	12	25	2799.367
#196	MAFF	13	12	25	660.484
#197	RUNX1T1	13	15	28	873.701
#198	HOXA1	13	10	23	697.542
#199	EGR3	13	11	24	241.171
#200	TCF7	12	16	28	2314.677
#201	NR5A2	12	15	27	254.771
#202	MEIS3	12	11	23	289.741
#203	TSHZ2	12	13	25	791.383
#204	LEF1	12	16	28	731.844
#205	NKX2-3	12	13	25	935.579
#206	HOXB7	12	10	22	406.896
#207	ETV5	12	17	29	1087.345
#208	HMGA1	12	21	33	1641.487
#209	TEF	12	9	21	137.001
#210	STAT6	12	18	30	673.521
#211	SIX3	12	16	28	1659.846
#212	PAX7	12	12	24	1631.696
#213	TFCP2L1	12	13	25	457.011
#214	VENTX	12	22	34	3709.504
#215	PBX4	12	18	30	2638.626
#216	NR6A1	12	21	33	1836.236
#217	NR1H4	12	19	31	1153.657
#218	ZNF174	12	21	33	3147.754
#219	NFYA	11	17	28	914.35
#220	GLI3	11	15	26	308.938
#221	POU2F2	11	15	26	333.664
#222	MLLT10	11	15	26	5918.376
#223	FOSB	11	9	20	1076.328
#224	PITX2	11	12	23	715.781
#225	HOXA2	11	6	17	243.715
#226	POU2F1	11	20	31	1881.036
#227	ELK1	11	10	21	6363.302
#228	JUNB	11	9	20	1874.653
#229	MITF	11	14	25	2297.207
#230	ETV4	11	12	23	1653.44
#231	TRIM29	11	17	28	1914.957
#232	HOXA9	11	6	17	544.109
#233	PCGF2	11	22	33	1387.806
#234	DLX2	11	13	24	183.663
#235	KLF16	11	16	27	389.453
#236	PITX1	11	20	31	1053.118
#237	ZSCAN12	11	9	20	291.363
#238	TCF21	11	16	27	2169.099
#239	E2F2	11	20	31	1139.703
#240	HOXD8	11	13	24	469.694
#241	MAFK	11	21	32	3042.192
#242	AHR	11	13	24	676.948
#243	NANOG	11	20	31	2935.059
#244	DLX3	10	11	21	3340.817
#245	LHX9	10	20	30	547.684
#246	IRX3	10	13	23	332.927
#247	ISL2	10	14	24	1083.256
#248	IRX5	10	13	23	1219.712
#249	TBX1	10	13	23	1652.023
#250	CSRNP3	10	14	24	1053.908
#251	ZNF135	10	14	24	578.324
#252	NFE2L3	10	13	23	2530.375
#253	SOX13	10	12	22	575.228
#254	ENO1	10	17	27	2486.587
#255	GATA3	10	11	21	349.967
#256	VDR	10	12	22	655.123
#257	RUNX3	10	12	22	201.532
#258	NFKB2	10	11	21	705.374
#259	RORA	10	16	26	1548.273
#260	ANKRD30A	10	16	26	1059.927
#261	TEAD1	10	16	26	1293.883
#262	FOXO3	10	15	25	506.681
#263	AFF4	10	16	26	1129.153
#264	EGR1	10	10	20	1862.074
#265	NFIB	10	17	27	1103.571
#266	TLX1	10	14	24	1695.785
#267	NFIA	10	18	28	1555.369
#268	RCOR1	10	16	26	1559.031
#269	T	10	13	23	1193.924
#270	TAL1	10	17	27	728.896
#271	NFIC	10	15	25	787.066
#272	ZNF83	10	16	26	1968.44
#273	ONECUT1	10	12	22	1174.381
#274	ZKSCAN3	10	18	28	1016.425
#275	NKX2-8	10	19	29	1408.368
#276	PGR	10	14	24	3726.639
#277	ZSCAN18	10	13	23	435.347
#278	TADA3	10	13	23	1298.589
#279	FOXL1	9	13	22	516.034
#280	POU4F1	9	19	28	532.582
#281	ZIC1	9	14	23	94.697
#282	HOXB2	9	14	23	555.397
#283	LHX1	9	20	29	1852.741
#284	GRHL3	9	11	20	979.083
#285	C12orf28	9	15	24	541.032
#286	FOXH1	9	17	26	2031.281
#287	GSX1	9	15	24	250.724
#288	NR5A1	9	19	28	2446.933
#289	ZNF193	9	17	26	810.706
#290	NCOR1	9	9	18	343.13
#291	CREB3L2	9	13	22	1178.455
#292	TFDP1	9	14	23	216.82
#293	TWIST1	9	13	22	5702.281
#294	ZNF81	9	19	28	939.492
#295	FEV	9	22	31	2019.266
#296	WT1	9	10	19	268.735
#297	FOXK1	8	15	23	870.612
#298	RFXAP	8	17	25	850.775
#299	NPAS1	8	12	20	223.296
#300	ATF6B	8	19	27	1921.622
#301	ZNF33B	8	19	27	1832.46
#302	TCF7L2	8	11	19	540.84
#303	SPDEF	8	16	24	1371.26
#304	TADA2A	8	19	27	2385.804
#305	ETV2	8	14	22	764.354
#306	FOXE1	8	23	31	2494.393
#307	PBX1	8	13	21	10251.451
#308	HOPX	8	16	24	527.907
#309	NKX2-1	8	18	26	2208.01
#310	PPARG	8	13	21	1806.063
#311	POU6F2	8	11	19	126.765
#312	ZNF85	8	17	25	502.491
#313	ZSCAN4	8	15	23	2086.813
#314	POU3F1	8	16	24	1774.219
#315	BHLHE41	8	20	28	318.452
#316	IKZF3	8	15	23	938.018
#317	ZIC5	8	13	21	277.193
#318	TBX20	8	12	20	1372.845
#319	GATA1	8	15	23	564.952
#320	PPARD	8	10	18	505.213
#321	NR4A3	8	14	22	3439.008
#322	RORB	8	17	25	659.449
#323	GATA6	8	21	29	14152.822
#324	PTH	8	21	29	1275.526
#325	TFAP2D	8	12	20	4475.06
#326	SCAND1	8	10	18	121.144
#327	ZFP42	7	19	26	1764.55
#328	MEOX1	7	14	21	854.194
#329	ZNF396	7	15	22	1043.955
#330	STAT2	7	14	21	1151.009
#331	SOX21	7	15	22	619.579
#332	ZNF483	7	17	24	605.458
#333	ZNF24	7	21	28	850.446
#334	KDM5A	7	17	24	633.497
#335	ZNF500	7	14	21	516.728
#336	BLZF1	7	13	20	297.775
#337	ZSCAN20	7	14	21	326.794
#338	SREBF1	7	19	26	1013.132
#339	TFAP2C	7	15	22	249.771
#340	VTN	7	7	14	299.351
#341	ATOH1	7	16	23	209.89
#342	SMAD2	7	12	19	318.226
#343	EPAS1	7	19	26	4246.188
#344	GSC2	7	16	23	1079.09
#345	HOXB6	7	17	24	497.377
#346	TP73	7	17	24	3273.289
#347	POU2F3	7	19	26	1824.849
#348	TSC22D1	7	16	23	501.645
#349	ZNF287	7	16	23	1121.146
#350	TBX5	7	17	24	1962.112
#351	SLC26A3	7	22	29	1442.386
#352	ARNTL2	7	21	28	1089.859
#353	ZNF215	7	15	22	3335.877
#354	TBX22	7	17	24	1546.947
#355	GLI2	7	11	18	867.062
#356	SPIC	7	19	26	2013.914
#357	IRF4	7	19	26	2147.306
#358	FOXB1	7	14	21	1670.049
#359	GCM1	7	19	26	1247.453
#360	BUD31	7	17	24	628.512
#361	ZHX3	7	18	25	904.556
#362	RCAN1	7	14	21	118.905
#363	RBPJL	7	11	18	761.06
#364	TCF20	7	13	20	6317.815
#365	FOXP3	7	15	22	669.781
#366	JUND	7	11	18	573.268
#367	ELK4	7	14	21	955.454
#368	FOXA1	6	18	24	2215.748
#369	ERG	6	18	24	747.653
#370	FLI1	6	18	24	1777.373
#371	SP140	6	12	18	367.86
#372	ERF	6	15	21	936.143
#373	POU1F1	6	21	27	1143.238
#374	RARB	6	8	14	3962.529
#375	ETV6	6	18	24	159.12
#376	ALS2CR8	6	15	21	350.787
#377	ZNF71	6	13	19	591.683
#378	CREM	6	11	17	1032.169
#379	PAX8	6	21	27	816.353
#380	GBX2	6	15	21	318.577
#381	CTBP1	6	13	19	814.474
#382	HOXD4	6	12	18	701.154
#383	FOXN4	6	8	14	1556.943
#384	FOXP2	6	17	23	358.13
#385	FOXD3	6	14	20	607.274
#386	EBF1	6	13	19	602.772
#387	MYNN	6	15	21	1083.604
#388	ESR1	6	19	25	1797.948
#389	HNF1A	6	11	17	556.408
#390	CREB3L1	6	18	24	727.779
#391	HOXA4	6	12	18	300.939
#392	NPAT	6	18	24	5528.241
#393	ZNF154	6	20	26	990.142
#394	SMAD6	6	15	21	743.66
#395	CREB3L3	6	18	24	470.215
#396	TBX3	6	17	23	4713.929
#397	HOXD1	5	17	22	909.444
#398	ZNF444	5	15	20	996.405
#399	NR1I3	5	19	24	2800.333
#400	MXD1	5	22	27	1230.888
#401	ESX1	5	17	22	1194.552
#402	SCAND2	5	11	16	886.332
#403	RARA	5	15	20	243.423
#404	HMG20B	5	17	22	896.431
#405	ETV7	5	16	21	244.445
#406	ZNF157	5	22	27	979.532
#407	SOX5	5	18	23	1271.189
#408	TFAP2B	5	22	27	606.85
#409	ZFHX3	5	16	21	657.207
#410	SIN3A	5	17	22	1137.101
#411	NR4A1	5	8	13	1123.511
#412	SIX6	5	11	16	3963.884
#413	TULP4	5	11	16	101.754
#414	ZFHX4	5	16	21	1075.798
#415	EHF	5	13	18	1225.451
#416	IKZF1	5	17	22	586.338
#417	MSX2	5	19	24	413.699
#418	REST	5	19	24	846.359
#419	HR	5	17	22	214.262
#420	SIX4	5	9	14	413.904
#421	ZNF639	5	14	19	670.073
#422	RERE	5	13	18	272.308
#423	DMRT2	5	10	15	137.019
#424	ZBTB38	5	12	17	569.093
#425	ZNF80	5	19	24	554.597
#426	ZNF165	5	9	14	1244.559
#427	DMBX1	5	14	19	2920.152
#428	SIM2	5	15	20	1073.427
#429	BARX1	5	18	23	1479.738
#430	MYF5	5	20	25	1506.979
#431	HOXD13	5	14	19	163.57
#432	PAX3	5	18	23	793.68
#433	TLX2	5	16	21	819.153
#434	ELF3	5	19	24	1613.078
#435	TBX19	5	14	19	140.164
#436	ZNF90	5	19	24	1029.415
#437	ZNF93	5	22	27	351.719
#438	GATA5	5	14	19	1329.048
#439	NPAS2	5	15	20	271.6
#440	FOXC2	5	19	24	634.955
#441	HOXC5	5	15	20	993.626
#442	HSF5	4	15	19	572.017
#443	PHOX2B	4	15	19	588.12
#444	PLSCR1	4	18	22	376.063
#445	MESP1	4	19	23	1211.049
#446	RAX2	4	17	21	637.278
#447	TBX6	4	14	18	169.653
#448	NEUROG1	4	15	19	971.058
#449	SNAPC5	4	17	21	362.445
#450	PURB	4	15	19	394.249
#451	ONECUT2	4	18	22	466.218
#452	ELF5	4	18	22	2581.303
#453	RUNX2	4	16	20	421.412
#454	NFE2	4	20	24	1478.407
#455	VSX1	4	21	25	1104.812
#456	LHX8	4	18	22	1280.625
#457	PRDM2	4	13	17	848.534
#458	YY1	4	17	21	1980.041
#459	ESRRB	4	19	23	1267.652
#460	LMX1A	4	20	24	1316.659
#461	GATA4	4	11	15	295.579
#462	IRX4	4	17	21	634.198
#463	ESR2	4	13	17	784.261
#464	CREBZF	4	17	21	267.342
#465	CDKN2A	4	18	22	4040.428
#466	ZSCAN23	4	16	20	250.218
#467	ZNF3	4	15	19	412.169
#468	ZFP36L1	4	16	20	509.206
#469	BNC1	4	19	23	681.62
#470	PBX3	4	20	24	2530.184
#471	STRN3	4	18	22	256.119
#472	IRF5	3	8	11	33.873
#473	HIRA	3	18	21	537.219
#474	NKX6-2	3	20	23	496.894
#475	HMGB2	3	13	16	182.73
#476	ASCL2	3	14	17	4909.983
#477	DMRT1	3	17	20	278.652
#478	SPIB	3	20	23	2813.3
#479	POU4F3	3	12	15	894.342
#480	KLF17	3	20	23	9349.131
#481	TP63	3	16	19	470.192
#482	OTX2	3	21	24	362.06
#483	ZSCAN2	3	17	20	334.97
#484	SOX30	3	18	21	263.604
#485	MAF	3	19	22	1220.146
#486	HCFC1	2	23	25	498.545
#487	KDM5B	2	15	17	278.738
#488	CREBBP	2	16	18	975.13
#489	MLL	2	20	22	616.447
#490	IRF6	2	17	19	143.618
#491	ZNF397	2	30	32	456.356
#492	ZNF207	1	22	23	224.55
#493	HNRNPAB	1	16	17	183.05
#494	HMGA2	1	22	23	144.226
#495	NRL	1	16	17	625.68
#496	RARG	1	15	16	333.37
#497	PPARA	1	22	23	1839.402
#498	MEF2D	1	15	16	45.987
#499	SIM1	1	21	22	411.559
#500	EVX1	0	16	16	0