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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MEIS1	56	3	59	298.844
#2	KLF4	37	4	41	180.25
#3	ERG	37	4	41	72.106
#4	FLI1	34	8	42	842.301
#5	ETS2	34	11	45	9314.98
#6	FOXF1	34	2	36	2288.597
#7	ZEB1	34	3	37	53.299
#8	TCF21	33	5	38	391.128
#9	TBX2	33	1	34	9.021
#10	CBFA2T3	32	6	38	1972.013
#11	HMGA1	32	11	43	1144.588
#12	E2F8	30	6	36	2821.327
#13	SOX4	30	10	40	4007.427
#14	KLF6	29	7	36	173.822
#15	MAFF	29	7	36	242.761
#16	TAL1	29	5	34	4731.557
#17	FOXM1	29	5	34	1495.567
#18	NR2F6	27	5	32	2781.783
#19	RCAN1	27	9	36	682.523
#20	ETV4	27	5	32	4647.807
#21	HHEX	26	9	35	5321.923
#22	KLF9	26	14	40	3725.744
#23	HDAC2	26	7	33	3320.648
#24	MTA1	26	12	38	1466.393
#25	MEF2A	26	10	36	716.244
#26	EPAS1	25	10	35	1057.28
#27	NKX2-1	25	7	32	3302.817
#28	CREBL2	25	14	39	2976.545
#29	NR2F1	25	10	35	1162.353
#30	TBX3	24	4	28	28.87
#31	STAT5B	24	12	36	7566.184
#32	MAF	24	4	28	485.532
#33	STAT6	24	8	32	2373.657
#34	ARNTL2	24	9	33	2745.841
#35	SOX17	23	10	33	1624.688
#36	JUND	23	6	29	929.411
#37	FOXF2	22	7	29	164.106
#38	ZNF193	22	13	35	2475.416
#39	ZNF500	22	5	27	1021.548
#40	RB1	22	6	28	657.404
#41	PTTG1	22	6	28	742.517
#42	FOXN3	21	8	29	620.694
#43	FOXO1	21	8	29	2054.106
#44	SOX12	21	7	28	1460.166
#45	ADNP2	21	8	29	3045.262
#46	C11orf9	21	12	33	1685.567
#47	FOXA2	21	5	26	1747.048
#48	TRIM22	20	11	31	2478.528
#49	SIX2	20	12	32	3350.227
#50	IRX5	20	10	30	1949.235
#51	TCF3	20	7	27	768.942
#52	HDAC1	20	11	31	4315.818
#53	NFYC	20	6	26	2531.702
#54	SPDEF	20	14	34	6721.496
#55	NFE2L2	20	12	32	2256.279
#56	NFATC3	20	10	30	1538.851
#57	NFIL3	19	8	27	1677.021
#58	TFAP2C	19	12	31	3374.859
#59	CREM	19	7	26	2425.122
#60	VDR	18	14	32	2159.803
#61	LASS6	18	12	30	870.577
#62	ETV1	18	14	32	1501.938
#63	TSC22D1	18	8	26	715.859
#64	ZSCAN16	18	9	27	3099.216
#65	FOSB	18	7	25	573.936
#66	SMAD6	17	10	27	791.524
#67	HOXB7	17	13	30	3170.455
#68	HMGB2	17	12	29	2706.963
#69	TAF6	17	8	25	2425.545
#70	YY1	17	13	30	1118.703
#71	ZNF3	17	13	30	1488.678
#72	ZEB2	17	8	25	180.089
#73	MYBL2	17	4	21	751.099
#74	NFYB	17	7	24	172.655
#75	SOX9	17	14	31	4378.694
#76	ZFPM2	17	7	24	645.783
#77	HNRNPAB	17	6	23	552.892
#78	SLC2A4RG	17	6	23	279.8
#79	IRF8	17	11	28	882.719
#80	ZNF83	17	10	27	3867.105
#81	GTF2H4	17	11	28	1862.415
#82	DRAP1	16	9	25	1007.371
#83	ENO1	16	13	29	6430.25
#84	SOLH	16	9	25	1684.714
#85	BUD31	16	13	29	2412.745
#86	GATA3	16	11	27	2971.921
#87	KLF2	16	9	25	682.911
#88	FOS	16	8	24	295.617
#89	KLF10	16	8	24	329.56
#90	GATA2	16	10	26	282.102
#91	NOLC1	16	9	25	1200.023
#92	HLF	15	15	30	2244.929
#93	IRF3	15	9	24	926.728
#94	SALL2	15	9	24	1150.223
#95	HOXA5	15	7	22	157.282
#96	NR4A1	15	6	21	1084.769
#97	FOXJ3	15	10	25	2688.885
#98	MZF1	15	13	28	1792.052
#99	ZFP36L2	15	12	27	1986.285
#100	NR3C1	15	12	27	1616.401
#101	SOX13	15	6	21	469.882
#102	KDM5B	15	13	28	1756.133
#103	HOXA10	15	10	25	1912.794
#104	YBX1	15	11	26	2908.652
#105	LMO4	15	11	26	2264.034
#106	TAF12	15	9	24	1838.827
#107	NR4A3	15	6	21	1472.907
#108	UBN1	15	10	25	1892.071
#109	PRRX2	14	9	23	1440.943
#110	ZNF277	14	8	22	2021.338
#111	JUN	14	12	26	1428.69
#112	HOXC10	14	10	24	2300.977
#113	JUNB	14	9	23	589.942
#114	ZNF238	14	12	26	2266.194
#115	ZNF85	14	4	18	616.889
#116	ZSCAN18	14	12	26	1251.887
#117	PBX1	14	16	30	2828.047
#118	ZNF117	14	11	25	1393.44
#119	KLF11	14	12	26	368.137
#120	NFE2L3	14	10	24	2454.514
#121	CREB1	14	12	26	2962.068
#122	TFCP2L1	14	13	27	2424.061
#123	PBX3	14	11	25	2955.546
#124	GATA6	14	13	27	4475.154
#125	TBX4	14	10	24	316.176
#126	TFAM	14	8	22	1296.252
#127	CEBPB	13	7	20	502.832
#128	SREBF2	13	14	27	7542.269
#129	CNBP	13	16	29	1907.401
#130	MNX1	13	14	27	6123.282
#131	ZBTB48	13	9	22	956.144
#132	MEF2C	13	15	28	3804.772
#133	PITX1	13	10	23	2583.992
#134	NR3C2	13	13	26	1798.718
#135	TSC22D3	13	14	27	869.278
#136	NFATC1	13	8	21	506.65
#137	SATB1	13	10	23	1329.085
#138	BTG2	13	13	26	1870.874
#139	BARX1	13	11	24	1908.082
#140	PA2G4	13	10	23	766.565
#141	TFAP2A	13	17	30	3907.556
#142	MSRB2	13	7	20	1048.398
#143	FOXK2	13	14	27	1421.07
#144	ASCL1	13	6	19	1700.286
#145	PRDM1	12	9	21	684.899
#146	PPARG	12	19	31	1998.822
#147	SNAI2	12	15	27	2093.719
#148	LHX3	12	5	17	373.598
#149	TCF12	12	9	21	1480.544
#150	AATF	12	11	23	987.5
#151	GAS7	12	4	16	104.011
#152	SCML1	12	12	24	2036.057
#153	DLX4	12	11	23	3871.501
#154	ZNF207	12	9	21	1401.927
#155	TFEB	12	8	20	1613.32
#156	CSDA	12	9	21	1078.049
#157	MNT	12	13	25	1732.849
#158	HCLS1	12	13	25	643.341
#159	PHF1	12	10	22	2111.953
#160	MEOX2	12	8	20	2074.51
#161	NR2F2	12	13	25	606.805
#162	GTF2I	12	12	24	2892.439
#163	AHR	12	14	26	2465.362
#164	NFAT5	12	13	25	1686.946
#165	STAT5A	12	4	16	563.63
#166	POU5F1B	12	12	24	2034.89
#167	NPAS2	12	12	24	1207.577
#168	TFEC	12	5	17	207.923
#169	NOTCH1	12	10	22	760.674
#170	ATF3	12	4	16	587.305
#171	MBD1	12	7	19	488.851
#172	SNAPC4	12	7	19	880.709
#173	EGR4	12	7	19	1192.98
#174	TFDP1	12	9	21	1599.565
#175	TRIM28	12	12	24	2058.463
#176	ZNF75D	12	14	26	1972.938
#177	HOPX	12	11	23	2226.55
#178	TCF4	12	11	23	913.96
#179	MAX	12	14	26	5173.388
#180	HOXD4	12	12	24	1293.344
#181	POU2F1	12	7	19	1037.029
#182	GLI3	12	10	22	1388.323
#183	HOXB2	12	8	20	2185.572
#184	ATF2	11	14	25	2644.782
#185	HINFP	11	9	20	980.633
#186	ZFHX4	11	9	20	1957.737
#187	ZXDC	11	10	21	1743.079
#188	GTF2IRD1	11	15	26	1794.838
#189	GABPB1	11	11	22	2210.097
#190	GATAD1	11	11	22	1779.06
#191	PITX2	11	4	15	603.525
#192	IRF6	11	9	20	1550.233
#193	ZNF148	11	9	20	1036.192
#194	FOSL2	11	9	20	1633.632
#195	NFKB1	11	8	19	1191.745
#196	CREBZF	11	12	23	1907.957
#197	HOXD1	11	15	26	3166.249
#198	BATF3	11	3	14	216.869
#199	BHLHE40	11	10	21	602.777
#200	SMAD4	10	13	23	2347.765
#201	HIF3A	10	8	18	1032.266
#202	TEAD4	10	11	21	908.558
#203	SCAND1	10	10	20	1349.593
#204	HMG20A	10	11	21	2120.339
#205	ZKSCAN1	10	17	27	1747.324
#206	CUX1	10	11	21	1127.522
#207	ADNP	10	15	25	2832.31
#208	SIX1	10	16	26	1951.996
#209	ZNF217	10	17	27	1236.812
#210	E2F5	10	12	22	866.651
#211	REL	10	10	20	1801.502
#212	GABPA	10	9	19	936.227
#213	LEF1	10	8	18	935.539
#214	TGIF1	10	16	26	3811.787
#215	ARID4A	10	8	18	876.927
#216	TRPS1	10	13	23	1713.96
#217	CITED2	10	14	24	1136.444
#218	EHF	10	13	23	1491.413
#219	TULP4	10	12	22	1551.379
#220	LZTR1	10	12	22	1885.953
#221	SP3	10	11	21	1251.79
#222	ZKSCAN4	10	10	20	472.284
#223	NFX1	10	7	17	1169.346
#224	PLSCR1	10	18	28	1571.17
#225	RUNX1T1	9	8	17	1607.123
#226	EGR3	9	5	14	968.352
#227	MAFB	9	12	21	1049.299
#228	STAT1	9	13	22	1378.02
#229	CDKN2A	9	16	25	2111.535
#230	MEIS2	9	12	21	449.118
#231	RUNX3	9	13	22	639.885
#232	IRF7	9	14	23	1230.326
#233	TP63	9	10	19	2727.228
#234	MYCN	9	6	15	1273.335
#235	IRF4	9	8	17	426.455
#236	TCF7L1	9	13	22	1798.987
#237	TCF25	9	7	16	371.621
#238	ELF1	9	11	20	4612.085
#239	AFF1	9	12	21	815.406
#240	MMP14	9	8	17	1015.748
#241	E4F1	9	14	23	1165.571
#242	RERE	9	14	23	2423.401
#243	DMTF1	9	12	21	1679.016
#244	ETS1	9	6	15	184.41
#245	MLL	9	13	22	2127.495
#246	IRF2	9	9	18	1295.859
#247	TAF10	9	12	21	821.026
#248	UBP1	9	11	20	2488.509
#249	NFYA	9	9	18	575.83
#250	ELF2	9	7	16	842.034
#251	ZNF263	9	12	21	751.968
#252	PRDM2	9	11	20	2060.495
#253	TEAD1	9	9	18	946.174
#254	HOXC4	9	6	15	612.891
#255	KLF3	9	12	21	2197.103
#256	RXRB	9	9	18	1275.441
#257	HOXB1	9	3	12	812.759
#258	T	9	7	16	750.285
#259	ZNF268	8	10	18	918.424
#260	KLF5	8	14	22	3040.062
#261	HSF4	8	12	20	973.034
#262	ARNT	8	12	20	2180.257
#263	MLX	8	9	17	773.419
#264	CBFB	8	7	15	1499.042
#265	HSF1	8	10	18	1531.548
#266	HMG20B	8	7	15	952.091
#267	STRN3	8	8	16	592.731
#268	FOXD1	8	7	15	742.51
#269	BRD8	8	15	23	966.501
#270	TARDBP	8	15	23	2146.109
#271	NCOR1	8	13	21	1745.89
#272	PRRX1	8	9	17	1148.615
#273	MAFG	8	13	21	1378.124
#274	SPEN	8	7	15	1282.533
#275	FOSL1	8	13	21	2349.672
#276	FOXA1	8	17	25	3389.092
#277	CTCF	8	12	20	1422.627
#278	BCL6	8	13	21	844.579
#279	KDM5A	8	15	23	1166.885
#280	GATAD2A	8	11	19	1182.897
#281	MYC	8	7	15	174.808
#282	MGA	8	9	17	1403.402
#283	AR	8	9	17	2080.069
#284	NR5A2	8	7	15	279.69
#285	MYNN	8	11	19	1921.732
#286	SOX2	8	15	23	1537.088
#287	EDF1	8	15	23	1953.657
#288	AEBP1	8	11	19	1529.108
#289	RORA	8	16	24	1243.649
#290	ZIC3	8	6	14	1264.027
#291	E2F3	8	15	23	1865.499
#292	IRF1	8	12	20	1022.493
#293	TAF5	8	8	16	825.766
#294	HOXC11	8	5	13	359.178
#295	TFCP2	8	13	21	2512.58
#296	ZNF274	8	13	21	1907.148
#297	ZNF323	8	16	24	1593.126
#298	ELF3	8	16	24	574.533
#299	ATF4	7	9	16	673.692
#300	FOXO3	7	16	23	1123.723
#301	SRF	7	9	16	264.104
#302	CEBPD	7	10	17	245.388
#303	ATF6	7	11	18	991.744
#304	SMAD3	7	12	19	1061
#305	BACH1	7	11	18	230.378
#306	ATF1	7	17	24	1399.482
#307	TCF7	7	10	17	1258.001
#308	HNF1B	7	8	15	617.905
#309	AHCTF1	7	5	12	669.73
#310	ELK1	7	14	21	1524.484
#311	SMAD2	7	13	20	2252.541
#312	NPAT	7	10	17	703.766
#313	TFDP2	7	11	18	1289.495
#314	ZNF91	7	14	21	845.854
#315	ZNF444	7	13	20	1747.044
#316	MECOM	7	19	26	3367.752
#317	TCEAL1	7	14	21	1294.281
#318	PAX8	7	4	11	229.337
#319	MXD1	7	6	13	1888.206
#320	ERF	7	10	17	549.477
#321	PFDN1	7	12	19	2473.01
#322	PCGF2	7	14	21	1587.622
#323	FOXG1	7	6	13	991.74
#324	TSC22D4	7	10	17	578.142
#325	ZNF232	7	5	12	652.333
#326	CREB3L2	7	12	19	631.415
#327	HMGA2	7	14	21	1033.638
#328	NFATC4	7	7	14	788.702
#329	NFE2	7	10	17	1297.49
#330	MLLT10	7	10	17	1250.033
#331	HOXA1	7	9	16	934.294
#332	PKNOX2	7	9	16	669.44
#333	NR4A2	7	11	18	2075.586
#334	TCFL5	7	14	21	999.684
#335	NKX3-1	7	8	15	1015.762
#336	E2F1	6	9	15	427.754
#337	BATF	6	8	14	437.06
#338	CREBBP	6	9	15	836.131
#339	SPI1	6	10	16	648.55
#340	ZNF140	6	7	13	896.227
#341	STAT3	6	7	13	374.925
#342	RELB	6	9	15	735.521
#343	NFIB	6	10	16	395.075
#344	LHX6	6	9	15	1161.606
#345	ZNF219	6	11	17	4002.988
#346	NR1H4	6	6	12	509.424
#347	RELA	6	10	16	1453.484
#348	SP140	6	11	17	724.353
#349	NEUROD1	6	4	10	147.574
#350	PURA	6	17	23	594.545
#351	TGIF2	6	16	22	1679.053
#352	STAT4	6	12	18	860.243
#353	NFKB2	6	5	11	266.445
#354	LASS2	6	7	13	747.46
#355	XBP1	6	12	18	893.443
#356	SOX11	6	13	19	1536.907
#357	ZNF434	6	10	16	490.901
#358	HIRA	6	11	17	795.309
#359	HMGB1	6	9	15	364.06
#360	TP53	6	10	16	1570.396
#361	TFE3	6	13	19	845.42
#362	ESR1	6	11	17	859.857
#363	ZNF45	6	12	18	1642.476
#364	ZNF202	6	14	20	607.829
#365	CNOT8	6	12	18	698.318
#366	CEBPA	6	16	22	1224.488
#367	MAFK	6	12	18	586.876
#368	ZHX3	6	9	15	657.058
#369	TWIST1	6	9	15	794.152
#370	SREBF1	6	14	20	848.149
#371	BTAF1	6	15	21	1070.707
#372	CNOT7	6	11	17	1337.876
#373	GRHL2	6	17	23	981.679
#374	TEAD3	6	12	18	542.747
#375	TBX21	5	9	14	621.12
#376	SNAPC5	5	7	12	250.57
#377	HEY1	5	9	14	90.807
#378	E2F6	5	12	17	274.591
#379	SCMH1	5	7	12	454.842
#380	SLC30A9	5	14	19	2382.974
#381	ETV7	5	12	17	1124.71
#382	SUPT4H1	5	12	17	841.67
#383	NR1H3	5	10	15	455.365
#384	VAV1	5	7	12	607.673
#385	ZNF281	5	17	22	521.695
#386	GCFC1	5	12	17	3479.354
#387	TCF20	5	13	18	1119.449
#388	ETV6	5	8	13	349.97
#389	SIX3	5	6	11	263.467
#390	MSX1	5	7	12	207.826
#391	STAT2	5	8	13	917.336
#392	KLF7	5	11	16	462.886
#393	MEIS3P1	5	10	15	606.709
#394	ATF6B	5	10	15	963.731
#395	MSL3	5	9	14	1264.807
#396	HNRNPK	5	11	16	985.893
#397	ETV5	5	14	19	785.797
#398	NFIX	5	6	11	121.23
#399	MYCL1	5	10	15	454.018
#400	TSC22D2	5	17	22	1062.577
#401	NFE2L1	5	13	18	1203.536
#402	EGR2	5	13	18	1230.176
#403	HAND1	5	10	15	1261.617
#404	SATB2	5	4	9	246.701
#405	CBFA2T2	5	10	15	526.269
#406	ZNF189	4	12	16	743.24
#407	RCOR1	4	14	18	1256.264
#408	RBPJ	4	12	16	1199.852
#409	NR1D2	4	15	19	880.725
#410	MITF	4	11	15	300.421
#411	ONECUT2	4	7	11	230.24
#412	FUBP1	4	15	19	892.567
#413	SOX18	4	10	14	120.527
#414	ZNF131	4	13	17	999.796
#415	PEG3	4	13	17	448.249
#416	RBCK1	4	15	19	874.172
#417	ZGPAT	4	11	15	641.608
#418	TBX5	4	8	12	235.585
#419	NR1H2	4	16	20	1123.681
#420	HOXB5	4	8	12	942.018
#421	BHLHE41	4	15	19	870.906
#422	SPIB	4	9	13	502.866
#423	BACH2	4	9	13	567.412
#424	HOXB6	4	8	12	1517.83
#425	SOX15	4	8	12	316.993
#426	RARB	4	6	10	342.661
#427	DBP	4	11	15	546.72
#428	CLOCK	4	9	13	253.156
#429	USF2	4	12	16	670.017
#430	HNF4A	4	7	11	351.83
#431	YEATS4	4	12	16	1379.599
#432	PLAGL2	4	10	14	747.695
#433	FOXC1	4	14	18	634.883
#434	SUPT6H	3	14	17	380.645
#435	TRIM29	3	11	14	154.493
#436	HEY2	3	5	8	17.533
#437	ISL1	3	17	20	1515.644
#438	PBX2	3	8	11	589.843
#439	PHTF1	3	9	12	170.87
#440	BCL11B	3	9	12	411.833
#441	ZNF133	3	11	14	1003.572
#442	MEF2D	3	11	14	220.518
#443	CTBP1	3	13	16	494.884
#444	HIF1A	3	8	11	102.17
#445	ZNF93	3	7	10	145.666
#446	ZNF24	3	15	18	361.356
#447	ZNF165	3	15	18	1082.195
#448	ELF4	3	12	15	728.681
#449	HOXA4	3	9	12	24.263
#450	NR0B1	3	7	10	731.607
#451	TAF4	3	10	13	576.828
#452	ELK3	3	12	15	999.854
#453	ATF5	3	12	15	329.17
#454	DDIT3	3	11	14	452.162
#455	ZHX2	3	10	13	398.759
#456	NR2C1	3	15	18	958.468
#457	SMAD5	3	10	13	861.331
#458	ZFHX3	3	13	16	537.93
#459	RXRA	3	16	19	874.893
#460	CTNNB1	3	17	20	745.621
#461	GTF2H3	3	11	14	276.612
#462	PLAG1	3	13	16	866.511
#463	ARNT2	3	9	12	277.013
#464	ZIC1	3	7	10	738.079
#465	IKZF1	3	10	13	340.282
#466	CREB5	3	8	11	409.118
#467	PPARD	2	14	16	175.265
#468	NFIC	2	17	19	355.981
#469	CREB3	2	13	15	281.163
#470	CSRNP2	2	8	10	745.024
#471	ZBTB17	2	12	14	164.713
#472	EGR1	2	10	12	113.178
#473	HES1	2	15	17	302.294
#474	IRF5	2	11	13	1293.531
#475	CITED1	2	6	8	152.144
#476	HMBOX1	2	11	13	340.81
#477	FBXW7	2	16	18	282.93
#478	RUNX1	2	10	12	276.723
#479	PROX1	2	13	15	344.55
#480	ELF5	2	15	17	1052.04
#481	ZBTB38	2	12	14	649.393
#482	TAF7	2	13	15	511.6
#483	HSF2	2	16	18	208.448
#484	RFX5	2	10	12	332.78
#485	RFXANK	2	13	15	526.466
#486	ZFP36L1	2	20	22	298.238
#487	IRF9	2	11	13	306.919
#488	WNT5A	2	11	13	228.587
#489	BCL3	1	17	18	128.865
#490	ZNF394	1	11	12	59.586
#491	ZNF215	1	9	10	157.343
#492	TCF7L2	1	12	13	85.759
#493	FOXJ1	1	13	14	168.155
#494	SMAD1	1	13	14	522.769
#495	CIR1	1	11	12	83.253
#496	C2orf3	1	12	13	391.985
#497	RARA	1	10	11	80.033
#498	ARNTL	0	12	12	0
#499	HIC1	0	11	11	0
#500	CREB3L1	0	15	15	0