Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TEAD1	41	7	48	960.52
#2	MECOM	36	8	44	3162.869
#3	ENO1	36	6	42	543.986
#4	MYC	36	12	48	2503.903
#5	FOXA1	35	1	36	250.959
#6	PURA	34	2	36	251.24
#7	RXRB	33	7	40	1163.415
#8	AR	32	3	35	146.42
#9	TCF4	32	1	33	176.71
#10	FOXM1	31	4	35	929.418
#11	ARNTL2	30	9	39	2226.931
#12	MSX1	30	6	36	903.105
#13	EN1	29	12	41	1546.933
#14	BCL3	29	7	36	1815.077
#15	FOXC1	29	7	36	894.942
#16	ZFHX4	29	3	32	186.265
#17	NR2F2	29	5	34	3393.338
#18	TFDP2	28	3	31	140.372
#19	ZEB2	28	3	31	702.462
#20	ETV6	27	10	37	1175.877
#21	DLX4	27	11	38	3203.37
#22	MAFB	27	7	34	1634.089
#23	FOXF2	26	5	31	1258.257
#24	HMGA1	26	10	36	1028.769
#25	ZFP36L2	26	8	34	572.838
#26	HSF1	26	10	36	1902.199
#27	NFYC	26	3	29	1820.648
#28	TFDP1	25	6	31	378.198
#29	ZNF268	24	6	30	2131.121
#30	FOXO1	24	6	30	1437.648
#31	MEF2A	24	7	31	1066.226
#32	MEF2C	23	10	33	1771.084
#33	GTF2I	23	3	26	791.513
#34	FBXW7	23	12	35	2682.728
#35	MAFG	23	5	28	1307.699
#36	LEF1	22	4	26	207.274
#37	SOX9	22	14	36	2031.887
#38	SNAI2	22	10	32	1722.603
#39	BATF	22	6	28	633.459
#40	SPDEF	22	6	28	550.553
#41	E2F8	22	7	29	1740.63
#42	NFIX	22	8	30	1948.25
#43	JUND	22	9	31	812.45
#44	EGR2	21	6	27	919.853
#45	PRRX1	21	7	28	897.929
#46	GABPB1	21	12	33	1224.915
#47	PBX2	21	5	26	1439.942
#48	FLI1	21	5	26	325.243
#49	ERF	21	12	33	1811.982
#50	BHLHE40	21	7	28	491.544
#51	TFAP2C	21	11	32	1247.745
#52	ZNF238	21	10	31	761.508
#53	SOX18	21	10	31	1175.628
#54	HMGB2	20	11	31	2296.734
#55	C11orf9	20	11	31	1389.036
#56	VDR	20	9	29	2498.933
#57	HOXC10	20	4	24	1423.094
#58	SMAD4	20	7	27	1121.926
#59	BTG2	20	9	29	1660.249
#60	IRF8	20	8	28	992.677
#61	HIC1	20	18	38	2553.7
#62	TWIST1	20	7	27	484.181
#63	RUNX1T1	20	7	27	1135.701
#64	TCF3	20	11	31	939.691
#65	NFIC	19	4	23	738.284
#66	TGIF2	19	8	27	724.823
#67	IRX5	19	13	32	2796.044
#68	HMX1	19	7	26	1385.481
#69	MYCL1	19	6	25	651.916
#70	KLF4	19	14	33	1879.457
#71	GATA2	19	8	27	1625.145
#72	EHF	19	12	31	2768.581
#73	STAT1	19	11	30	1578.93
#74	ETV1	19	5	24	770.767
#75	NR4A3	19	9	28	1799.106
#76	POU3F3	18	8	26	1177.296
#77	TFAP2B	18	8	26	607.847
#78	C2orf3	18	16	34	1921.383
#79	ZFHX3	18	13	31	2204.63
#80	HOXB8	18	9	27	1748.392
#81	XBP1	17	11	28	897.903
#82	FOXI1	17	13	30	570.901
#83	SIM2	17	9	26	1509.998
#84	ERG	17	8	25	1564.336
#85	MYOG	17	10	27	1796.295
#86	HOXA5	17	9	26	1595.792
#87	TFDP3	17	11	28	1119.2
#88	HOXC13	17	14	31	1807.711
#89	AEBP1	17	9	26	1145.364
#90	BRD8	16	7	23	594.328
#91	NFE2L3	16	11	27	520.501
#92	TFEC	16	5	21	261.555
#93	MMP14	16	11	27	689.573
#94	RORA	16	14	30	2951.221
#95	MEIS2	16	10	26	876.441
#96	SALL1	16	7	23	1288.995
#97	EPAS1	16	14	30	1071.81
#98	ZFPM2	16	11	27	1027.907
#99	BHLHE41	16	10	26	1526.787
#100	E2F5	16	11	27	1183.562
#101	ELF5	16	11	27	775.145
#102	CREBBP	16	8	24	2067.486
#103	KLF6	16	9	25	909.234
#104	RUNX3	16	13	29	1192.999
#105	ZSCAN16	16	7	23	1230.204
#106	HCLS1	16	8	24	423.222
#107	HOPX	15	13	28	859.922
#108	MXD1	15	15	30	2197.247
#109	SCML1	15	8	23	1072.424
#110	BLZF1	15	14	29	2587.755
#111	RCAN1	15	6	21	1739.182
#112	STAT6	15	12	27	537.386
#113	MEOX1	15	8	23	1112.23
#114	LMX1B	15	12	27	1879.6
#115	MYBL2	15	12	27	1471.149
#116	NFATC4	15	14	29	2130.438
#117	NFIB	15	16	31	2631.922
#118	ATF6	15	9	24	947.175
#119	SMAD5	15	6	21	407.549
#120	NR2F1	15	9	24	480.277
#121	NFYA	15	8	23	407.54
#122	AHR	15	11	26	2280.797
#123	HIF3A	15	12	27	1758.41
#124	HOXA6	15	8	23	1170.284
#125	LMO4	15	20	35	1618.17
#126	NPAT	14	12	26	1266.77
#127	PPARG	14	14	28	801.502
#128	STAT2	14	12	26	1666.038
#129	ZNF434	14	10	24	1830.851
#130	TCF7L1	14	11	25	616.898
#131	TRPS1	14	8	22	914.185
#132	HMGA2	14	8	22	1737.246
#133	IRF7	14	8	22	489.472
#134	SP1	14	10	24	949.17
#135	IRF6	14	7	21	527.205
#136	EGR3	14	7	21	807.905
#137	PITX1	14	12	26	1649.183
#138	NR4A1	14	12	26	1758.807
#139	ELK1	14	11	25	823.003
#140	NFAT5	14	15	29	1482.227
#141	MEF2D	14	8	22	1846.505
#142	BCL11B	14	14	28	1035.04
#143	MLXIPL	14	7	21	798.06
#144	FOSB	14	5	19	694.055
#145	ARNTL	14	8	22	840.531
#146	RBPJL	14	7	21	1099.155
#147	FOXF1	14	8	22	623.212
#148	HOXB6	14	15	29	2086.821
#149	SOX10	13	7	20	736.891
#150	CEBPA	13	12	25	1042.651
#151	SPI1	13	14	27	617.28
#152	CREB3L1	13	12	25	1501.484
#153	ZNF323	13	11	24	1538.752
#154	ARNT	13	13	26	673.236
#155	SREBF1	13	12	25	1247.645
#156	CDKN2A	13	13	26	2701.25
#157	TP53	13	15	28	1621.218
#158	MTA2	13	11	24	1090.285
#159	ZXDC	13	10	23	949.805
#160	ZFP37	13	9	22	704.665
#161	ESRRB	13	10	23	725.985
#162	CBFA2T2	13	9	22	905.982
#163	HNF1B	13	14	27	1971.887
#164	GABPA	13	11	24	996.34
#165	HOXD4	13	11	24	1235.61
#166	ZBTB48	13	15	28	1888.407
#167	NKX2-8	12	14	26	2249.895
#168	RFXAP	12	15	27	1975.227
#169	PKNOX1	12	9	21	830.537
#170	CUX2	12	17	29	2061.884
#171	FOXP3	12	9	21	1444.333
#172	GRHL2	12	16	28	1053.519
#173	FOS	12	11	23	822.2
#174	TFAP2A	12	10	22	596.333
#175	HOXA7	12	12	24	1686.698
#176	SPIB	12	19	31	2465.222
#177	EGR1	12	9	21	948.621
#178	TBX4	12	8	20	1589.442
#179	MLLT10	12	11	23	1170.304
#180	HOXD10	12	3	15	394.649
#181	ZNF167	12	16	28	1135.465
#182	MZF1	12	10	22	1235.523
#183	FOSL2	12	10	22	924.084
#184	NFKB2	12	10	22	1900.881
#185	KLF9	12	15	27	1596.367
#186	ARNT2	12	15	27	1306.141
#187	ATF6B	12	13	25	2176.963
#188	PTTG1	12	8	20	633.008
#189	ALS2CR8	12	10	22	1445.655
#190	HOXB7	12	10	22	1444.519
#191	TSC22D3	12	7	19	611.278
#192	ESRRG	12	13	25	732.817
#193	PLSCR1	12	14	26	666.237
#194	PHF1	12	8	20	1807.908
#195	ARID3A	12	13	25	878.127
#196	AFF1	12	14	26	2631.124
#197	HCFC1	12	16	28	1091.198
#198	SMAD9	12	7	19	713.767
#199	TADA2A	12	15	27	1751.716
#200	POU3F1	12	14	26	1112.182
#201	PPARA	12	16	28	1129.374
#202	MAFF	12	12	24	798.811
#203	HES1	11	10	21	1685.693
#204	MSX2	11	13	24	2632.368
#205	HOXA9	11	14	25	1445.087
#206	TCF21	11	11	22	905.981
#207	NR2C1	11	13	24	1730.021
#208	SMAD1	11	11	22	1699.597
#209	ZNF81	11	13	24	2224.298
#210	ELK4	11	13	24	636.79
#211	ZNF155	11	11	22	1868.329
#212	ZEB1	11	12	23	451.279
#213	CTBP1	11	14	25	1566.524
#214	VTN	11	12	23	1780.119
#215	ATOH1	11	12	23	1291.275
#216	RARA	11	12	23	688.262
#217	ZNF131	11	11	22	1199.692
#218	TSHZ2	11	11	22	2233.956
#219	GLI2	11	12	23	1924.878
#220	RXRG	11	10	21	2530.899
#221	KLF15	11	14	25	1417.742
#222	PROX1	11	7	18	511.419
#223	BACH2	11	8	19	400.563
#224	E2F4	11	7	18	334.219
#225	SP4	11	12	23	1020.416
#226	IKZF1	10	12	22	713.193
#227	NR3C2	10	17	27	1605.562
#228	MBD1	10	9	19	1425.252
#229	ZNF175	10	9	19	525.046
#230	CSDA	10	8	18	975.557
#231	BARX1	10	12	22	902.129
#232	MAFK	10	14	24	1078.632
#233	HOXA1	10	15	25	1259.554
#234	NR2E3	10	9	19	1102.416
#235	PHOX2A	10	15	25	1829.636
#236	TAF1B	10	10	20	1337.971
#237	HSF2	10	8	18	1103.308
#238	JUN	10	16	26	2424.559
#239	NKX3-2	10	14	24	1133.057
#240	ZNF91	10	14	24	1308.499
#241	BUD31	10	8	18	700.456
#242	NR2F6	10	16	26	1623.393
#243	MAF	10	15	25	1429.54
#244	NR1H4	10	9	19	1764.452
#245	SMAD6	10	14	24	1586.833
#246	HOXB1	10	13	23	1182.697
#247	SOX4	10	12	22	830.223
#248	TADA3	10	9	19	475.122
#249	ST18	10	12	22	1178.199
#250	NEUROG1	10	10	20	1127.195
#251	DLX6	10	12	22	988.554
#252	GATA1	10	15	25	2356.645
#253	PBX1	10	10	20	647.948
#254	SIX3	9	13	22	1597.521
#255	KLF5	9	12	21	659.097
#256	TLX2	9	13	22	1064.919
#257	NR2E1	9	9	18	847.315
#258	TEAD4	9	9	18	742.112
#259	GAS7	9	14	23	1017.29
#260	POU2F2	9	12	21	686.288
#261	ZNF236	9	13	22	2426.374
#262	CREB5	9	12	21	968.908
#263	ZNF132	9	12	21	945.063
#264	GATA6	9	11	20	1157.816
#265	ALX3	9	13	22	1247.882
#266	SATB1	9	9	18	1133.972
#267	PLAG1	9	8	17	771.105
#268	HOXA4	9	10	19	1183.532
#269	HOXB2	9	13	22	1210.771
#270	BATF3	9	13	22	1146.16
#271	CREBZF	9	12	21	1353.712
#272	GTF2H3	9	9	18	827.686
#273	ALX4	9	11	20	856.089
#274	LASS6	9	12	21	677.513
#275	ZNF165	9	12	21	770.972
#276	CTNNB1	9	7	16	909.443
#277	NR5A2	9	10	19	1039.078
#278	MYF6	9	14	23	1829.512
#279	ZNF277	8	12	20	1224.094
#280	FOXD3	8	15	23	1036.419
#281	ZNF643	8	15	23	1295.709
#282	TFCP2L1	8	11	19	861.165
#283	MNX1	8	10	18	723.209
#284	POU3F2	8	16	24	1781.469
#285	NFYB	8	10	18	656.474
#286	MYF5	8	13	21	1302.273
#287	SOX2	8	14	22	1827.872
#288	PPARD	8	7	15	594.406
#289	HR	8	11	19	970.558
#290	FUBP1	8	11	19	1422.725
#291	TCF7	8	10	18	1467.25
#292	ZNF41	8	12	20	908.183
#293	FOSL1	8	12	20	1525.036
#294	HSF4	8	9	17	855.597
#295	HOXB9	8	12	20	1012.63
#296	SIX5	8	12	20	1183.163
#297	THRA	8	12	20	1534.398
#298	HOXB13	8	12	20	756.214
#299	TCF7L2	8	8	16	1375.313
#300	MYOD1	8	8	16	1768.442
#301	BNC1	8	9	17	1344.973
#302	SOX13	8	9	17	546.764
#303	PRDM1	8	18	26	879.192
#304	VSX1	8	12	20	913.943
#305	ZNF93	8	9	17	649.96
#306	PTH	8	11	19	1547.165
#307	NPAS2	8	15	23	951.616
#308	ZHX3	8	11	19	708.226
#309	TFAP4	8	12	20	836.42
#310	KLF12	8	12	20	1270.377
#311	ZNF117	8	12	20	831.427
#312	LHX2	8	19	27	2174.584
#313	HOXC11	8	8	16	783.209
#314	ZNF500	8	11	19	1300.505
#315	MEOX2	8	15	23	1672.868
#316	ALX1	8	10	18	941.378
#317	HAND2	8	10	18	938.357
#318	FOXH1	8	10	18	1368.678
#319	NR0B1	8	10	18	1256.926
#320	TAL1	8	12	20	1302.659
#321	POU3F4	7	10	17	1110.378
#322	ATF5	7	13	20	1019.13
#323	FOXB1	7	10	17	764.307
#324	NKX3-1	7	13	20	923.626
#325	NEUROD1	7	16	23	1571.32
#326	HDAC2	7	13	20	655.312
#327	LHX1	7	11	18	1205.717
#328	GATA3	7	20	27	1662.375
#329	ZIC1	7	15	22	705.173
#330	IRF5	7	10	17	328.749
#331	OVOL1	7	15	22	2080.574
#332	ZNF3	7	8	15	493
#333	FOXA2	7	13	20	691.062
#334	ZNF154	7	13	20	1402.896
#335	HLF	7	18	25	1617.629
#336	TLX3	7	11	18	743.661
#337	TBX19	7	11	18	1203.737
#338	REST	7	11	18	491.147
#339	TP63	7	13	20	686.52
#340	ELF3	7	16	23	1672.84
#341	ONECUT2	7	9	16	547.738
#342	FOXE1	7	10	17	1094.068
#343	HNF4A	7	10	17	621.8
#344	PHOX2B	7	10	17	664.096
#345	PAX5	7	12	19	1061.314
#346	SOX21	7	13	20	1057.195
#347	SCAND2	7	14	21	1028.885
#348	FOXO4	7	10	17	537.173
#349	PAX8	7	12	19	1110.632
#350	TCF15	7	8	15	492.07
#351	FOXC2	7	12	19	797.596
#352	EN2	7	12	19	1242.304
#353	ZSCAN18	7	12	19	738.633
#354	SOX5	7	10	17	934.692
#355	ZNF157	6	11	17	1570.371
#356	TAF4	6	12	18	780.772
#357	ZNF444	6	18	24	844.53
#358	HOXA11	6	12	18	1052.401
#359	SOX30	6	15	21	789.004
#360	POU5F1B	6	12	18	753.874
#361	ZNF80	6	12	18	478.221
#362	NFX1	6	13	19	565.463
#363	HOXA10	6	9	15	653.231
#364	NKX2-1	6	7	13	464.18
#365	FOXD1	6	12	18	408.322
#366	TSC22D2	6	11	17	843.451
#367	ETV2	6	13	19	872.456
#368	CITED1	6	12	18	645.784
#369	ASCL1	6	16	22	787.037
#370	NRL	6	13	19	723.626
#371	ELF4	6	17	23	1145.316
#372	HOXD11	6	16	22	1181.113
#373	IRX4	6	11	17	452.426
#374	IRF4	6	11	17	1447.248
#375	ISL1	6	10	16	366.43
#376	HOXC5	6	13	19	991.334
#377	GATA4	6	16	22	1103.587
#378	MYT1L	6	9	15	549.107
#379	HMG20B	6	7	13	289.287
#380	HOXB3	6	12	18	1017.051
#381	FOXO3	6	15	21	523.636
#382	PAX4	6	9	15	605.543
#383	ZNF135	6	10	16	375.135
#384	TRIM29	6	14	20	638.664
#385	HNF4G	6	10	16	885.727
#386	HOXA2	6	10	16	268.055
#387	MSRB2	6	11	17	480.69
#388	CRX	6	5	11	659.915
#389	ATF3	6	10	16	510.843
#390	SRY	6	15	21	1036.698
#391	POU1F1	6	8	14	843.17
#392	SIM1	6	18	24	1712.815
#393	TP73	6	8	14	489.131
#394	SLC26A3	6	15	21	1394.534
#395	TAF13	6	14	20	773.855
#396	ZNF446	6	10	16	1544.155
#397	DLX2	6	18	24	1109.11
#398	NR4A2	6	14	20	1230.749
#399	TLX1	6	13	19	678.891
#400	TCF12	5	16	21	1248.944
#401	PAX6	5	14	19	1003.28
#402	SCRT1	5	11	16	616.758
#403	PRRX2	5	19	24	1122.517
#404	FOXJ1	5	15	20	892.638
#405	MLL	5	11	16	851.243
#406	SNAPC5	5	13	18	918.081
#407	TBX5	5	11	16	383.528
#408	TBR1	5	12	17	360.835
#409	PGR	5	12	17	825.374
#410	SIX1	5	12	17	708.619
#411	RERE	5	12	17	375.264
#412	RORB	5	11	16	568.821
#413	WT1	5	16	21	707.047
#414	E2F2	5	13	18	618.133
#415	RB1	5	8	13	599.852
#416	SATB2	5	13	18	865.75
#417	RUNX1	5	12	17	879.671
#418	RORC	5	12	17	480.214
#419	HOXD13	5	5	10	483.253
#420	HOXD1	5	13	18	546.188
#421	FOXE3	5	12	17	658.369
#422	WNT5A	5	16	21	554.783
#423	NANOG	5	9	14	459.975
#424	YY1	5	9	14	442.406
#425	EGR4	5	14	19	1560.407
#426	FOXL2	5	9	14	513.306
#427	NPAS1	5	12	17	927.837
#428	RUNX2	5	8	13	448.621
#429	NFATC1	5	16	21	842.665
#430	E2F1	5	17	22	491.203
#431	NR6A1	5	16	21	989.467
#432	SMAD3	5	15	20	956.68
#433	ZNF202	5	10	15	743.138
#434	ESR2	5	16	21	1018.932
#435	EMX1	5	14	19	1253.467
#436	IKZF3	5	14	19	1092.268
#437	ETV3	5	13	18	407.62
#438	VENTX	5	11	16	638.828
#439	HESX1	4	10	14	1149.51
#440	HOXD9	4	9	13	275.394
#441	HOXC8	4	11	15	1087.719
#442	ETV5	4	16	20	512.43
#443	RARG	4	14	18	1231.508
#444	MYT1	4	13	17	1101.84
#445	HOXD3	4	15	19	1214.092
#446	FOXG1	4	14	18	618.362
#447	HEY1	4	17	21	675.016
#448	OLIG2	4	11	15	378.128
#449	RARB	4	17	21	627.107
#450	GCM1	4	11	15	797.745
#451	ZSCAN2	4	10	14	422.506
#452	POU2F3	4	14	18	604.172
#453	SNAPC4	4	10	14	458.801
#454	DBP	4	16	20	539.997
#455	GSC2	4	15	19	595.553
#456	ONECUT1	4	14	18	809.495
#457	NR5A1	4	10	14	680.486
#458	PEG3	4	15	19	523.744
#459	NKX2-5	4	18	22	754.588
#460	SIX2	4	16	20	899.261
#461	ZIC3	4	16	20	1001.565
#462	POU4F3	4	11	15	788.882
#463	DMRT1	4	17	21	1200.437
#464	T	4	11	15	924.781
#465	HOXA3	4	11	15	1370.567
#466	POU4F1	3	15	18	615.862
#467	POU6F2	3	9	12	302.958
#468	NR1I3	3	15	18	1998.564
#469	PKNOX2	3	13	16	352.337
#470	ESR1	3	13	16	346.498
#471	ASCL2	3	9	12	284.491
#472	POU6F1	3	13	16	368.053
#473	TBX2	3	18	21	646.59
#474	ZFP36L1	3	10	13	706.131
#475	CEBPE	3	12	15	683.245
#476	PAX7	3	11	14	514.977
#477	CREM	3	14	17	790.119
#478	ZNF174	3	11	14	342.351
#479	PRDM2	3	15	18	272.964
#480	TBX1	3	20	23	587.051
#481	NR1I2	3	8	11	271.212
#482	CSRNP3	3	8	11	323.173
#483	ZNF639	3	6	9	326.064
#484	NKX6-1	3	17	20	629.818
#485	PDX1	3	12	15	341.397
#486	LZTS1	3	11	14	337.508
#487	TEF	3	14	17	717.561
#488	ETV4	2	13	15	129.817
#489	GBX2	2	16	18	302.128
#490	FOXD2	2	14	16	636.931
#491	ZNF287	2	13	15	264.052
#492	HEY2	2	11	13	305.049
#493	KDM5B	2	12	14	293.234
#494	SOX11	2	14	16	94.784
#495	STRN3	2	11	13	268.207
#496	TBX6	2	13	15	339.099
#497	PITX2	1	12	13	149.731
#498	MYCN	1	18	19	391.872
#499	NFE2	1	12	13	120.403
#500	PAX3	1	17	18	183.151