Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NFE2L2	100	5	105	716.983
#2	CSDA	99	8	107	1233.242
#3	YBX1	91	4	95	988.042
#4	MITF	86	4	90	642.164
#5	TGIF1	85	8	93	1315.691
#6	CNBP	81	5	86	1014.922
#7	SOX9	75	5	80	1082.555
#8	MZF1	74	6	80	644.847
#9	ZNF148	72	10	82	346.891
#10	CNOT8	72	7	79	276.141
#11	SCML1	66	14	80	1672.323
#12	BHLHE41	65	10	75	1439.278
#13	ADNP	64	5	69	633.306
#14	EDF1	64	8	72	14544.821
#15	RFXANK	63	12	75	1617.029
#16	EPAS1	62	4	66	2344.383
#17	ENO1	61	5	66	166.742
#18	ZNF207	58	9	67	1526.736
#19	NFE2L1	58	5	63	982.463
#20	TP63	57	6	63	2777.962
#21	NFKB1	56	8	64	640.049
#22	CEBPD	55	9	64	538.55
#23	ELF1	53	15	68	1660.206
#24	STAT3	52	12	64	978.904
#25	LZTS1	50	3	53	387.979
#26	SMAD4	49	7	56	203.041
#27	HMGA1	49	13	62	1982.006
#28	MYC	47	9	56	2145.437
#29	ZKSCAN1	46	14	60	349.921
#30	MAFB	44	10	54	39043.94
#31	DDIT3	44	7	51	5653.384
#32	KLF5	43	9	52	3871.51
#33	RARA	42	9	51	438.929
#34	FOXO3	42	16	58	2498.261
#35	ZNF131	42	11	53	548.302
#36	NR4A3	40	9	49	390.377
#37	WNT5A	39	8	47	953.535
#38	ZNF83	39	13	52	4293.37
#39	ZNF274	38	15	53	10393.431
#40	ZNF140	38	11	49	829.533
#41	HOXB7	37	16	53	3630.228
#42	SOX4	36	10	46	953.805
#43	CSRNP2	35	11	46	1994.437
#44	HMGA2	35	14	49	1343.335
#45	AHR	34	13	47	3327.21
#46	TCF7L2	34	14	48	798.921
#47	ETV5	34	13	47	1906.893
#48	TFCP2	34	19	53	824.016
#49	TWIST1	33	11	44	876.015
#50	TCFL5	33	16	49	3916.963
#51	BACH1	33	20	53	1459.816
#52	THRA	33	13	46	1020.895
#53	ZNF394	33	13	46	951.86
#54	MNT	32	8	40	691.022
#55	TAF12	32	12	44	535.985
#56	GAS7	31	6	37	927.241
#57	TRIM22	31	9	40	1501.543
#58	NR1D2	31	16	47	1333.401
#59	BHLHE40	31	18	49	1788.432
#60	MLX	31	15	46	1489.041
#61	HEY1	31	15	46	1052.503
#62	MAF	30	8	38	432.668
#63	RCOR1	30	13	43	472.702
#64	ARNTL	30	15	45	795.17
#65	DRAP1	30	18	48	8724.425
#66	NFYB	29	16	45	250.362
#67	ZEB1	29	8	37	967.139
#68	ZNF167	29	12	41	5938.576
#69	MSRB2	29	11	40	1541.199
#70	GABPA	29	14	43	426.526
#71	TFDP2	28	13	41	4500.758
#72	SOX10	28	4	32	527.395
#73	PTTG1	28	13	41	2791.501
#74	ALS2CR8	28	14	42	2672.449
#75	STAT1	27	9	36	400.244
#76	ETS2	27	13	40	7748.688
#77	RBCK1	27	23	50	2894.081
#78	PURA	27	18	45	18748.325
#79	NFYC	27	19	46	759.95
#80	BLZF1	26	18	44	4661.067
#81	EGR3	26	13	39	1916.448
#82	ZIC1	25	15	40	559.262
#83	CBFB	25	14	39	275.545
#84	IRF6	25	6	31	170.714
#85	KLF6	24	13	37	237.621
#86	MLLT10	24	19	43	821.129
#87	RCAN1	23	14	37	678.823
#88	REL	23	17	40	961.766
#89	TFAP2C	23	14	37	1764.478
#90	JUN	22	15	37	3860.568
#91	TFDP1	22	18	40	247.24
#92	MEF2A	22	16	38	954.378
#93	FOXD1	22	13	35	1272.821
#94	HOXC4	22	11	33	988.847
#95	SMAD5	22	15	37	276.912
#96	RUNX3	22	11	33	1653.645
#97	ZNF165	21	18	39	3561.34
#98	GATAD1	21	12	33	91.758
#99	RB1	21	16	37	731.188
#100	ZHX2	21	17	38	3071.116
#101	KLF2	21	13	34	1662.685
#102	PKNOX2	21	8	29	181.21
#103	CREB1	21	21	42	3900.075
#104	HMG20B	20	15	35	934.914
#105	ATF3	20	16	36	1930.866
#106	FOXF2	20	18	38	2375.259
#107	DMTF1	20	9	29	360.734
#108	HOXB2	20	11	31	1821.146
#109	HOXD4	19	5	24	367.503
#110	GATA3	19	8	27	1048.841
#111	BTG2	19	18	37	848.344
#112	GRHL2	18	13	31	772.822
#113	LEF1	18	9	27	467.492
#114	NFYA	18	11	29	172.582
#115	GTF2I	18	15	33	663.136
#116	FOXD2	18	15	33	692.759
#117	TFAP2A	18	11	29	640.935
#118	FOXN3	17	19	36	1974.645
#119	STAT4	17	17	34	930.194
#120	IRF4	17	9	26	1057.004
#121	ZEB2	17	7	24	295.426
#122	LMO4	17	18	35	2762.91
#123	FOXO1	16	18	34	5117.458
#124	NR6A1	16	11	27	511.356
#125	NOTCH1	16	12	28	1126.73
#126	NFIB	16	12	28	1896.314
#127	RUNX1T1	16	15	31	3497.844
#128	SATB1	16	15	31	6992.254
#129	VDR	16	15	31	712.824
#130	PA2G4	15	16	31	276.082
#131	MECOM	15	10	25	689.288
#132	E2F1	15	15	30	784.656
#133	NFATC3	15	17	32	281.224
#134	IRX4	15	16	31	972.904
#135	SMAD1	15	12	27	3156.949
#136	AEBP1	15	15	30	1722.415
#137	NKX3-1	15	10	25	1009.797
#138	ELK4	15	15	30	782.318
#139	PLSCR1	15	14	29	470.944
#140	STAT5A	15	10	25	1097.202
#141	CDKN2A	15	14	29	1944.565
#142	ELK3	14	18	32	3580.402
#143	GATA2	14	16	30	591.515
#144	ZSCAN18	14	13	27	1867.483
#145	ELF3	14	8	22	1396.566
#146	BCL11B	14	12	26	1802.49
#147	ZNF75D	14	17	31	472.365
#148	KLF4	14	16	30	772.52
#149	ZNF45	14	14	28	259.175
#150	PITX2	14	15	29	6742.563
#151	MLL	14	20	34	1152.801
#152	JUND	14	16	30	1195.694
#153	REST	13	12	25	1276.413
#154	NR4A2	13	12	25	1212.699
#155	MAX	13	16	29	255.901
#156	SP140	13	8	21	489.908
#157	FOS	13	13	26	172.925
#158	ZNF91	13	14	27	2918.68
#159	PRRX2	13	14	27	644.317
#160	PEG3	13	12	25	932.414
#161	MGA	13	13	26	3179.526
#162	EN2	13	15	28	2056.875
#163	ZFP36L2	13	18	31	581.11
#164	NR2F2	13	19	32	2635.436
#165	PAX4	13	9	22	724.684
#166	ALX1	12	11	23	248.055
#167	SOX5	12	11	23	182.821
#168	RUNX1	12	9	21	16806.342
#169	NR2F1	12	13	25	2011.568
#170	ETV1	12	15	27	398.811
#171	HOXB6	12	12	24	406.996
#172	TAF4B	12	16	28	3866.519
#173	CTBP1	12	13	25	39774.408
#174	SOX13	12	16	28	710.657
#175	EN1	11	12	23	8707.411
#176	BNC1	11	11	22	975.85
#177	E2F8	11	12	23	392.938
#178	MYBL2	11	12	23	411.037
#179	RXRG	11	14	25	144.858
#180	FOXC1	11	14	25	762
#181	HSF1	11	14	25	995.908
#182	PLAG1	11	11	22	1664.235
#183	ZNF192	11	16	27	5183.546
#184	MAFF	11	13	24	737.659
#185	SPEN	11	16	27	1883.124
#186	HSF2	11	17	28	845.841
#187	STAT6	11	20	31	568.217
#188	MYCL1	11	16	27	659.004
#189	CITED2	10	21	31	1171.372
#190	RAX	10	16	26	1953.096
#191	TBX5	10	15	25	9306.275
#192	ATF6	10	11	21	629.946
#193	HOXA10	10	10	20	381.164
#194	HOXA9	10	13	23	449.902
#195	TEF	10	16	26	8394.34
#196	ZFPM2	10	16	26	1188.137
#197	ZFP37	10	14	24	2504.011
#198	NFAT5	10	14	24	1732.469
#199	HEY2	10	14	24	1175.977
#200	TP53	10	14	24	1510.379
#201	TCF7L1	9	14	23	416.132
#202	NR1I2	9	14	23	14960.86
#203	RORA	9	13	22	10377.289
#204	HIRA	9	13	22	685.866
#205	ELF5	9	11	20	2029.21
#206	ARNT	9	19	28	1917.582
#207	ISL1	9	12	21	634.44
#208	HOXC10	9	16	25	2425.348
#209	BCL6	9	19	28	351.79
#210	TAF13	9	21	30	544.428
#211	SMAD6	9	7	16	307.084
#212	NR4A1	9	11	20	225.445
#213	TFAM	9	25	34	2610.736
#214	HOXA5	9	17	26	3663.784
#215	FBXW7	9	20	29	795.332
#216	MEF2D	9	14	23	1105.847
#217	FOXH1	9	11	20	4111.704
#218	MLXIPL	8	11	19	1390.743
#219	NEUROD2	8	14	22	5686.915
#220	NR5A1	8	13	21	3588.994
#221	ZFHX3	8	14	22	461.074
#222	ERG	8	13	21	299.86
#223	FOXF1	8	14	22	2974.777
#224	PAX3	8	13	21	471.542
#225	SALL1	8	15	23	2091.57
#226	POU6F1	8	10	18	521.696
#227	CUX2	8	15	23	272.475
#228	TBX6	8	13	21	1410.453
#229	RFXAP	7	16	23	1888.09
#230	SIX3	7	18	25	1163.105
#231	PHOX2B	7	14	21	8905.652
#232	FOSL2	7	20	27	814.445
#233	ZNF202	7	17	24	1787.879
#234	SPIB	7	9	16	2336.335
#235	ZIC3	7	14	21	1529.323
#236	TCF12	7	14	21	391.325
#237	EGR1	7	14	21	986.5
#238	NPAS1	7	9	16	520.618
#239	ZNF155	7	19	26	402.499
#240	RXRB	7	12	19	78.901
#241	TBX10	7	13	20	1216.537
#242	TFAP2B	7	14	21	434.449
#243	HCFC1	7	14	21	482.927
#244	TADA3	7	12	19	3267.804
#245	NFIC	7	19	26	2738.326
#246	AFF1	7	13	20	4927.394
#247	ELF4	7	17	24	630.981
#248	VSX1	7	12	19	2214.462
#249	NFATC4	6	14	20	406.48
#250	HNF1B	6	17	23	26912.945
#251	PAX6	6	7	13	100.685
#252	BATF	6	13	19	248.445
#253	SATB2	6	18	24	401.704
#254	CITED1	6	17	23	764.164
#255	ZNF215	6	16	22	1265.678
#256	HHEX	6	19	25	442.351
#257	ZNF117	6	13	19	165.988
#258	HOXA6	6	15	21	1519.878
#259	SOX15	6	15	21	250.004
#260	MYCN	6	13	19	5485.325
#261	NPAS2	6	17	23	288.794
#262	ASCL1	6	14	20	1075.665
#263	FOXL1	6	13	19	1227.84
#264	SIM1	6	14	20	9874.587
#265	BUD31	6	17	23	567.371
#266	FOXM1	6	16	22	551.192
#267	NFX1	6	20	26	3646.489
#268	HR	6	17	23	267.609
#269	ZNF238	6	15	21	1803.265
#270	MYT1	6	8	14	686.307
#271	PROX1	6	17	23	7522.464
#272	TCF4	6	12	18	754.603
#273	ZNF135	6	11	17	153.083
#274	SOX18	6	19	25	519.836
#275	SOX11	6	13	19	162.883
#276	SPDEF	6	14	20	690.127
#277	DBP	6	17	23	1002.125
#278	TRIM29	5	10	15	74.363
#279	MEF2C	5	9	14	83.86
#280	MBD1	5	13	18	427.93
#281	POU3F2	5	20	25	1301.458
#282	OLIG2	5	11	16	735.925
#283	HOXA7	5	21	26	347.421
#284	SPI1	5	13	18	175.067
#285	ZNF444	5	8	13	28.576
#286	TFDP3	5	12	17	87.855
#287	ZNF639	5	12	17	2130.452
#288	CREB3L1	5	15	20	2046.537
#289	DLX2	5	17	22	18265.046
#290	CREM	5	15	20	1199.513
#291	NEUROG1	5	10	15	1270.902
#292	FOXD3	5	16	21	1311
#293	ALX3	5	13	18	1037.574
#294	SIX2	5	13	18	6104.886
#295	DLX6	5	9	14	341.144
#296	HOXC13	5	16	21	328.507
#297	SIX5	5	11	16	5572.63
#298	KLF1	5	10	15	1973.402
#299	BARX1	5	9	14	429.959
#300	HIC1	5	10	15	528.563
#301	NFIX	5	18	23	492.105
#302	ZNF81	5	13	18	589.905
#303	NR2F6	5	17	22	3817.374
#304	ZBTB48	5	16	21	998.311
#305	FOXE3	5	12	17	1812.941
#306	ZNF434	5	14	19	1819.615
#307	PRRX1	5	16	21	1937.398
#308	CBFA2T2	5	18	23	708.7
#309	CREB5	5	16	21	2092.297
#310	MYOG	5	12	17	3183.829
#311	ZFP36L1	4	14	18	2016.641
#312	CEBPA	4	19	23	216.874
#313	GATA6	4	17	21	237.209
#314	HNF4A	4	14	18	192.632
#315	HOXD13	4	13	17	106.107
#316	EMX1	4	11	15	560.81
#317	TCF3	4	12	16	165.647
#318	CLOCK	4	13	17	1206.428
#319	POU3F3	4	13	17	760.82
#320	AR	4	10	14	206.429
#321	SIX6	4	9	13	55.69
#322	MTA2	4	16	20	2489.931
#323	ZNF3	4	17	21	3174.673
#324	ETS1	4	12	16	795.232
#325	ZNF24	4	22	26	2716.92
#326	PITX1	4	12	16	75.246
#327	SLC26A3	4	10	14	423.078
#328	ZNF132	4	15	19	1592.606
#329	ESRRG	4	17	21	1563.825
#330	THRB	4	12	16	1016.944
#331	HES1	4	9	13	128.863
#332	ONECUT1	4	14	18	906.421
#333	FOXA2	4	11	15	345.874
#334	HOXA1	4	18	22	321.246
#335	PBX1	4	16	20	167.593
#336	GATA4	4	8	12	32.651
#337	DLX4	4	14	18	599.025
#338	IRF8	4	10	14	2042.109
#339	HMX1	4	9	13	54.274
#340	CBFA2T3	4	16	20	3132.461
#341	ESR2	4	17	21	311.259
#342	PPARA	4	17	21	143.738
#343	TRPS1	4	22	26	432.607
#344	GATA1	4	7	11	7791.544
#345	ZSCAN2	4	12	16	2353.269
#346	FOXG1	4	10	14	47.912
#347	POU3F1	4	17	21	203.496
#348	TFEC	4	11	15	568.477
#349	ARNTL2	4	13	17	516.632
#350	POU2F2	4	8	12	728.741
#351	BRD8	4	12	16	9136.993
#352	HAND2	4	13	17	4740.413
#353	RARG	3	9	12	905.174
#354	BCL3	3	16	19	1180.814
#355	SHOX	3	15	18	216.553
#356	TCF15	3	12	15	486.379
#357	HOXA11	3	13	16	267.559
#358	PAX5	3	10	13	2016.241
#359	NANOG	3	14	17	392.592
#360	HOXA4	3	13	16	474.874
#361	HLF	3	11	14	248.502
#362	MEOX2	3	19	22	2986.067
#363	TCF25	3	9	12	846.605
#364	POU2F3	3	10	13	539.928
#365	HOPX	3	11	14	2798.578
#366	HOXD3	3	15	18	577.205
#367	ZNF80	3	13	16	1201.321
#368	MMP14	3	24	27	1912.09
#369	TBX2	3	15	18	94.64
#370	GSC2	3	14	17	1523.522
#371	SCAND2	3	16	19	6589.766
#372	SOX2	3	14	17	2746
#373	FOXE1	3	13	16	77.813
#374	CREBZF	3	10	13	1729.873
#375	SOX17	3	11	14	955.378
#376	GCM1	3	15	18	667.208
#377	NFE2	3	17	20	1195.602
#378	PRDM2	3	11	14	1269.983
#379	NKX2-5	3	11	14	754.259
#380	SIX1	3	12	15	1221.911
#381	GLI2	3	14	17	846.952
#382	SOX21	3	10	13	447.449
#383	TSC22D3	3	17	20	79.182
#384	NR0B1	3	13	16	354.159
#385	CSRNP3	3	17	20	170.199
#386	E2F5	3	15	18	30.981
#387	TLX2	3	11	14	1514.714
#388	NPAT	3	11	14	120.165
#389	PAX7	3	14	17	1163.031
#390	VAV1	3	11	14	983.131
#391	ZNF157	3	16	19	872.095
#392	HNF1A	3	11	14	473.094
#393	ASCL2	3	7	10	147.488
#394	ESR1	3	14	17	607.227
#395	SNAPC5	3	11	14	374.624
#396	SP1	3	22	25	599.16
#397	ATF5	3	16	19	1275.659
#398	TBX1	2	10	12	557.445
#399	GBX2	2	12	14	870.19
#400	C11orf9	2	15	17	3111.187
#401	POU4F3	2	10	12	413.152
#402	HOXD1	2	12	14	1521.58
#403	FOSB	2	10	12	75.818
#404	ETV4	2	16	18	73.019
#405	ZNF287	2	18	20	17637.166
#406	PPARG	2	17	19	1287.861
#407	SRY	2	12	14	2217.325
#408	FOXB1	2	15	17	169.893
#409	SIM2	2	6	8	236.288
#410	IKZF1	2	10	12	788.434
#411	HIF3A	2	11	13	2222.483
#412	MXD1	2	16	18	83.131
#413	FUBP1	2	12	14	415.595
#414	ELK1	2	18	20	347.732
#415	SNAPC4	2	10	12	17.18
#416	PDX1	2	11	13	248.705
#417	RUNX2	2	14	16	457.721
#418	ZBTB17	2	14	16	4190.352
#419	NEUROD1	2	16	18	3383.34
#420	ZNF41	2	10	12	926.674
#421	RBPJL	2	9	11	186.721
#422	ALX4	2	10	12	3114.904
#423	HOXB1	2	13	15	966.127
#424	MSX2	2	9	11	630.064
#425	EGR4	2	10	12	641.918
#426	RARB	2	10	12	1304.037
#427	CRX	2	13	15	4122.449
#428	TSC22D2	2	17	19	3049.237
#429	RORB	2	17	19	139.844
#430	NR2E3	2	17	19	505.026
#431	EHF	2	12	14	64.598
#432	LHX2	2	20	22	169.744
#433	HOXB13	2	12	14	339.38
#434	MYF6	2	10	12	4442.169
#435	EGR2	2	18	20	127.211
#436	NR1I3	2	12	14	592.84
#437	VTN	2	14	16	6919.231
#438	PGR	1	11	12	46.945
#439	HNF4G	1	15	16	5615.346
#440	HEYL	1	11	12	28.263
#441	ZSCAN12	1	18	19	341.832
#442	ZNF174	1	11	12	1522.449
#443	TAL1	1	14	15	26.574
#444	NKX6-1	1	13	14	115.977
#445	KLF15	1	11	12	23.051
#446	POU1F1	1	15	16	314.787
#447	E2F2	1	13	14	1092.954
#448	FOXC2	1	12	13	34.139
#449	MNX1	1	14	15	284.088
#450	PKNOX1	1	15	16	953.816
#451	RERE	1	11	12	38.304
#452	NKX3-2	1	11	12	11.143
#453	HOXD9	1	12	13	76.022
#454	PAX8	1	14	15	58.927
#455	NKX2-1	1	12	13	210.782
#456	HOXD10	1	13	14	488.03
#457	ARNT2	1	14	15	10.908
#458	TLX3	1	12	13	513.002
#459	NR2E1	1	13	14	43.363
#460	DMRT1	1	12	13	115.377
#461	FOXL2	1	12	13	49.481
#462	SOX30	1	15	16	465.938
#463	HOXD11	1	14	15	63.83
#464	KDM5B	1	13	14	37.785
#465	ZNF154	1	13	14	784.676
#466	STAT2	1	16	17	1010.318
#467	POU4F1	1	12	13	28.001
#468	STRN3	1	15	16	145.139
#469	KLF9	1	15	16	25.971
#470	IRF5	1	14	15	1112.144
#471	TP73	1	8	9	2531.626
#472	MYF5	1	13	14	1000.638
#473	TCF21	1	11	12	493.194
#474	TADA2A	1	11	12	102.736
#475	WT1	1	12	13	285.465
#476	LMX1B	1	13	14	86.563
#477	LHX1	1	11	12	816.294
#478	POU4F2	1	10	11	16.262
#479	NFKB2	1	13	14	2577.298
#480	HOXB3	1	14	15	173.732
#481	KLF12	0	12	12	0
#482	HESX1	0	12	12	0
#483	FEV	0	12	12	0
#484	ZNF500	0	11	11	0
#485	FOXA1	0	12	12	0
#486	NKX2-8	0	14	14	0
#487	IKZF3	0	14	14	0
#488	HOXB8	0	8	8	0
#489	TAF4	0	15	15	0
#490	FLI1	0	14	14	0
#491	ST18	0	12	12	0
#492	PTH	0	11	11	0
#493	HSF4	0	15	15	0
#494	POU6F2	0	9	9	0
#495	YY1	0	10	10	0
#496	NR5A2	0	14	14	0
#497	FOXJ1	0	13	13	0
#498	HOXA2	0	15	15	0
#499	TSHZ2	0	13	13	0
#500	MYT1L	0	14	14	0