Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NPAT	132	3	135	515.19
#2	POU4F2	126	2	128	6516.074
#3	HMGA2	113	7	120	1891.436
#4	FOXA1	89	0	89	0
#5	ELK3	85	1	86	31.871
#6	PHOX2B	85	4	89	169.091
#7	HAND1	83	5	88	256.898
#8	GATA3	83	2	85	34.392
#9	E2F3	77	2	79	42.487
#10	JUND	75	6	81	559.094
#11	MAX	74	3	77	598.963
#12	HCLS1	73	3	76	1454.704
#13	NFYC	71	4	75	270.636
#14	TAL1	70	2	72	71.688
#15	ESR1	69	4	73	28.002
#16	E2F6	68	14	82	2067.216
#17	TSHZ2	68	14	82	796.729
#18	XBP1	68	4	72	47.177
#19	TADA3	68	10	78	2050.998
#20	ATF1	67	8	75	1388.797
#21	NFE2	67	0	67	0
#22	HOXA11	65	15	80	577.112
#23	SPDEF	63	9	72	1879.674
#24	ADNP2	62	10	72	312.587
#25	AR	61	6	67	74.16
#26	TBR1	61	10	71	936.2
#27	SPIB	60	14	74	1607.374
#28	TRIM22	60	2	62	563.653
#29	REXO4	59	12	71	1098.56
#30	MBD1	57	14	71	1161.086
#31	KLF2	57	8	65	1700.437
#32	BLZF1	56	18	74	1806.208
#33	NFYB	56	15	71	2386.646
#34	KLF15	56	10	66	2581.549
#35	SUPT6H	56	12	68	708.187
#36	TCF4	55	4	59	782.525
#37	SNAI2	55	3	58	620.788
#38	KLF1	55	6	61	9337.935
#39	ZNF83	55	5	60	513.473
#40	ZFPM2	54	12	66	2999.317
#41	TAF12	54	6	60	110.65
#42	EN1	53	5	58	28.58
#43	ZNF165	53	14	67	906.27
#44	ZNF217	53	6	59	310.276
#45	FOXC1	52	4	56	42.541
#46	GABPA	52	13	65	755.608
#47	NFYA	51	12	63	459.054
#48	CTBP1	51	6	57	501.619
#49	FOXM1	51	3	54	49.606
#50	NFATC3	51	16	67	1150.448
#51	IRX5	51	7	58	274.277
#52	SOX10	50	9	59	197.049
#53	AEBP1	50	4	54	137.328
#54	MZF1	49	10	59	442.433
#55	NFE2L1	48	11	59	1186.225
#56	IRF8	48	2	50	178.592
#57	NR3C1	47	7	54	1857.486
#58	FLI1	47	5	52	890.841
#59	ZGPAT	46	16	62	373.604
#60	LASS6	46	8	54	92.814
#61	CDKN2A	45	10	55	87.73
#62	HDAC2	45	8	53	287.505
#63	ENO1	45	13	58	2252.704
#64	CITED2	44	19	63	1286.108
#65	EPAS1	43	9	52	1145.336
#66	GTF2H3	42	28	70	2610.213
#67	MGA	42	16	58	515.185
#68	MYC	41	12	53	1134.57
#69	ZIC3	40	19	59	1376.017
#70	CNOT8	40	16	56	1935.318
#71	AHR	39	14	53	5152.034
#72	ISL1	39	17	56	732.557
#73	BHLHE40	38	9	47	229.781
#74	CREBZF	38	21	59	752.137
#75	MAFB	38	7	45	721.031
#76	RXRA	37	18	55	2167.07
#77	HNF1B	37	14	51	353.091
#78	SPI1	37	16	53	684.839
#79	ZEB2	37	13	50	546.549
#80	TFCP2	37	20	57	880.773
#81	PLSCR1	36	16	52	5597.959
#82	ESRRA	36	10	46	974.14
#83	STAT3	36	15	51	868.907
#84	CBL	36	24	60	2024.532
#85	HIF1A	35	15	50	4574.408
#86	HOXC5	35	23	58	3260.005
#87	PKNOX2	34	23	57	1407.987
#88	TFE3	34	16	50	1731.619
#89	HSF4	34	21	55	1485.229
#90	IKZF1	34	9	43	888.763
#91	TFAM	34	11	45	419.868
#92	PBX1	33	21	54	579.437
#93	MEF2C	33	8	41	560.367
#94	GTF2I	33	13	46	4172.069
#95	RUNX2	33	20	53	583.168
#96	HMGA1	32	12	44	191.405
#97	CEBPB	32	12	44	704.077
#98	ELF1	32	24	56	1218.496
#99	NFAT5	31	15	46	444.005
#100	ARNTL2	31	19	50	961.74
#101	CSDA	31	11	42	1975.387
#102	SOX11	31	15	46	578.874
#103	CBFB	31	10	41	456.589
#104	PBX2	31	25	56	1299.707
#105	BCL6	31	13	44	1602.492
#106	E2F1	31	14	45	927.316
#107	MAFF	30	17	47	1032.072
#108	E2F5	30	23	53	1923.288
#109	PPBPL2	30	16	46	197.709
#110	ZNF140	30	15	45	753.444
#111	SREBF1	30	8	38	2763.308
#112	SOX4	30	18	48	1186.273
#113	FOXC2	30	11	41	2715.449
#114	ARNTL	29	16	45	608.858
#115	SATB1	29	14	43	1484.828
#116	ERG	29	12	41	559.512
#117	SOX17	29	20	49	1545.84
#118	E2F4	29	18	47	831.161
#119	TP53	29	13	42	174.943
#120	SIM2	29	25	54	1771.942
#121	FOXO1	29	11	40	850.473
#122	MYF6	29	21	50	2080.028
#123	TLX2	28	24	52	1448.398
#124	HMGB2	28	7	35	1184.466
#125	HOXA5	28	19	47	1631.039
#126	TBX2	28	18	46	3871.176
#127	REST	28	28	56	1603.609
#128	NR2F6	28	17	45	404.184
#129	ZNF446	28	14	42	757.979
#130	MSX1	27	19	46	2557.004
#131	ECSIT	27	21	48	527.194
#132	SOX9	27	17	44	616.095
#133	NR2E1	27	23	50	4132.41
#134	ZNF91	27	12	39	437.444
#135	TBX10	27	26	53	1433.977
#136	IKZF3	27	20	47	6770.065
#137	KLF9	26	26	52	3595.298
#138	GLI2	26	20	46	1771.867
#139	STAT1	26	15	41	1247.495
#140	TCFL5	26	18	44	1959.189
#141	ZNF45	26	26	52	2884.653
#142	NFIB	26	18	44	297.13
#143	MYOD1	26	13	39	1466.24
#144	KLF6	26	15	41	309.534
#145	ZBTB48	26	12	38	543.855
#146	MLLT10	26	23	49	651.994
#147	PDX1	26	28	54	1942.016
#148	FOXF1	26	29	55	924.091
#149	EGR2	25	20	45	595.079
#150	POU6F1	25	11	36	223.939
#151	HOXD12	25	10	35	362.825
#152	HOXB2	25	12	37	271.212
#153	ZNF219	25	20	45	3728.026
#154	NR2C2	25	31	56	1703.056
#155	VENTX	25	19	44	1774.015
#156	BTG2	25	11	36	299.045
#157	MYBL2	25	9	34	309.228
#158	ZXDC	25	21	46	560.862
#159	POU2F2	25	22	47	610.152
#160	TFEB	25	13	38	194.111
#161	ZNF444	24	20	44	452.9
#162	HIRA	24	26	50	875.059
#163	TFEC	24	11	35	1284.064
#164	TRIM29	24	12	36	117.935
#165	LMO4	24	13	37	226.369
#166	ETV1	23	14	37	886.794
#167	GABPB1	23	21	44	776.589
#168	PRDM2	23	25	48	1001.816
#169	HSF1	23	14	37	998.099
#170	TAF5	23	13	36	1800.079
#171	HOXA9	23	13	36	619.339
#172	RUNX3	23	8	31	1898.214
#173	ELF4	23	17	40	839.04
#174	HOPX	22	17	39	2354.065
#175	E2F8	22	13	35	712.697
#176	ELF5	22	12	34	253.689
#177	TRPS1	22	11	33	1076.172
#178	OVOL1	22	29	51	2506.611
#179	HOXD4	22	23	45	1255.266
#180	SNAPC4	22	18	40	412.483
#181	POU3F4	21	26	47	951.653
#182	BHLHE41	21	16	37	1184.395
#183	HINFP	21	25	46	412.616
#184	MMP14	21	18	39	463.942
#185	YEATS4	21	19	40	2294.983
#186	SP140	21	6	27	2694.106
#187	FOS	21	10	31	224.335
#188	BRD8	21	26	47	1828.957
#189	BCL11B	20	10	30	1010.53
#190	HNF4A	20	21	41	649.12
#191	ZNF174	20	21	41	248.245
#192	MEOX2	20	10	30	214.721
#193	SMAD3	20	20	40	713.36
#194	PHOX2A	20	23	43	2406.013
#195	NR4A3	20	20	40	1536.565
#196	ETS1	20	28	48	2367.813
#197	ATF6	20	17	37	842.261
#198	GATA1	20	20	40	783.461
#199	FOXN3	19	16	35	519.519
#200	TEAD4	19	15	34	1799.008
#201	PEG3	19	31	50	1780.556
#202	RXRB	19	22	41	567.175
#203	OLIG2	19	22	41	1840.884
#204	RUNX1T1	19	15	34	613.045
#205	TCF7L2	19	27	46	760.294
#206	TBX19	19	16	35	190.434
#207	NR4A2	18	18	36	753.536
#208	JUN	18	16	34	405.703
#209	PPARA	18	19	37	1865.669
#210	RARA	18	20	38	563.182
#211	CUX1	18	26	44	2951.156
#212	ASCL2	18	31	49	1676.085
#213	STRN3	18	24	42	307.38
#214	NR1I3	18	26	44	1673.986
#215	NRL	18	20	38	3179.774
#216	PGR	18	16	34	217.746
#217	MEF2D	18	24	42	317.985
#218	NEUROG1	17	26	43	444.405
#219	ESR2	17	29	46	1334.483
#220	GAS7	17	27	44	474.601
#221	LHX6	17	22	39	616.903
#222	E2F2	17	23	40	798.442
#223	FOSL2	17	24	41	1335.227
#224	KLF5	17	20	37	1985.008
#225	SOX5	17	25	42	945.082
#226	FOXO4	17	28	45	2700.419
#227	MEOX1	17	20	37	714.577
#228	HOXD1	17	28	45	1858.215
#229	ESRRG	17	16	33	495.802
#230	HOXC8	17	29	46	800.145
#231	ZIC1	16	11	27	69.518
#232	ZSCAN18	16	18	34	427.541
#233	ZNF287	16	20	36	1664.657
#234	TP63	16	25	41	1326.85
#235	NANOG	16	28	44	2251.633
#236	CBFA2T2	16	31	47	837.763
#237	PRDM1	16	16	32	213.293
#238	C2orf3	16	21	37	463.471
#239	HOXB9	16	28	44	1405.43
#240	HOXA3	16	26	42	999.725
#241	ZNF202	16	26	42	1706.547
#242	MTA2	15	28	43	606.713
#243	MSX2	15	14	29	340.515
#244	ARNT2	15	14	29	556.818
#245	MXD1	15	16	31	479.19
#246	WNT5A	15	24	39	6727.881
#247	ZFP36L2	15	22	37	1113.453
#248	ST18	15	30	45	1251.31
#249	TFAP2C	15	18	33	412.828
#250	NFKB2	15	27	42	443.413
#251	HOXA7	15	19	34	756.387
#252	NEUROD1	15	22	37	562.077
#253	NR3C2	15	24	39	1062.3
#254	NR2C1	15	27	42	657.482
#255	ETV5	15	16	31	784.718
#256	HOXA2	15	29	44	2099.369
#257	HNF1A	15	27	42	2108.31
#258	HOXC10	15	22	37	2116.264
#259	MLL	15	25	40	1785.445
#260	SOX18	15	24	39	1677.887
#261	TFAP2B	15	20	35	1221.678
#262	PAX7	15	32	47	1466.134
#263	EGR1	14	15	29	1562.254
#264	HSF2	14	27	41	1232.027
#265	GATA6	14	24	38	1703.621
#266	ONECUT1	14	24	38	412.073
#267	HOXA4	14	30	44	3510.262
#268	CREB3L1	14	13	27	128.98
#269	HOXB1	14	26	40	1605.416
#270	LHX1	14	23	37	825.045
#271	TWIST1	14	18	32	720.479
#272	CITED1	14	20	34	654.496
#273	MEIS2	14	23	37	2016.98
#274	SMAD1	14	30	44	1239.177
#275	ONECUT2	14	26	40	1290.872
#276	PHF1	14	27	41	3110.799
#277	TFDP3	14	23	37	707.419
#278	RARG	14	33	47	1268.852
#279	NR1H4	14	28	42	1177.505
#280	HES1	14	30	44	1964.173
#281	NKX2-5	14	14	28	179.371
#282	HMG20B	14	30	44	1305.647
#283	NR5A1	14	33	47	1290.61
#284	NR2E3	13	29	42	1713.783
#285	USF2	13	27	40	353.11
#286	SCRT1	13	23	36	553.05
#287	MLXIPL	13	24	37	1521.644
#288	BNC1	13	28	41	982.213
#289	NKX3-2	13	32	45	1166.038
#290	HEY2	13	28	41	690.352
#291	NR0B1	13	28	41	1320.698
#292	ETV2	13	28	41	1086.07
#293	TBX3	13	11	24	45.773
#294	STAT6	13	19	32	812.181
#295	ELF2	13	28	41	1053.945
#296	SMAD6	13	32	45	859.047
#297	HOXB6	13	16	29	950.718
#298	NKX3-1	13	16	29	459.477
#299	GATA2	13	16	29	242.721
#300	HOXB7	13	23	36	1789.835
#301	ESRRB	13	27	40	622.104
#302	MEF2A	13	25	38	1053.875
#303	T	13	35	48	1805.875
#304	EHF	13	24	37	474.184
#305	ZNF154	13	34	47	2007.441
#306	ZNF41	12	33	45	1710.161
#307	ATF6B	12	22	34	2177.9
#308	TADA2A	12	30	42	396.189
#309	ZKSCAN1	12	21	33	291.612
#310	PRRX2	12	24	36	926.5
#311	CSRNP3	12	26	38	814.627
#312	GATA4	12	20	32	1886.394
#313	NR2F2	12	30	42	2057.307
#314	RUNX1	12	32	44	1087.451
#315	TSC22D2	12	32	44	1685.018
#316	MAF	12	13	25	196.114
#317	MYT1	12	26	38	361.385
#318	MSRB2	12	27	39	2717.703
#319	ZFHX3	12	26	38	331.347
#320	SIX3	12	15	27	304.873
#321	NR1I2	11	29	40	696.133
#322	KLF12	11	31	42	5349.922
#323	SOX21	11	26	37	1624.193
#324	SNAPC5	11	34	45	1664.052
#325	TEF	11	35	46	5364.899
#326	FOSB	11	12	23	261.199
#327	ZNF117	11	31	42	883.79
#328	NR2F1	11	22	33	263.179
#329	FOXI1	11	25	36	1075.474
#330	TBX6	11	40	51	1528.697
#331	TCF7	11	15	26	484.08
#332	NFIX	11	18	29	194.875
#333	ZNF80	11	41	52	1954.877
#334	NFX1	11	27	38	855.502
#335	PITX1	10	19	29	139.738
#336	FOXH1	10	26	36	422.057
#337	PROX1	10	31	41	886.099
#338	SLC26A3	10	25	35	797.252
#339	TBX5	10	29	39	1138.094
#340	FOXJ1	10	32	42	1786.963
#341	C11orf9	10	32	42	1262.761
#342	SIX1	10	23	33	410.588
#343	ZNF75D	10	30	40	678.867
#344	POU3F2	10	27	37	1347.55
#345	NKX2-8	10	35	45	2558.762
#346	EGR4	10	26	36	1458.871
#347	ATF5	10	31	41	4948.749
#348	MECOM	10	10	20	67.261
#349	HOXB3	10	22	32	1264.273
#350	TFAP2A	10	22	32	957.175
#351	FOSL1	10	27	37	1381.433
#352	PHTF1	10	24	34	930.385
#353	FOXE1	10	27	37	524.654
#354	EN2	10	26	36	1419.525
#355	SOX13	9	23	32	147.954
#356	HOXD11	9	29	38	1444.997
#357	ALS2CR8	9	26	35	729.632
#358	POU5F1B	9	30	39	442.709
#359	KDM5B	9	29	38	1414.35
#360	VSX1	9	31	40	1005.87
#361	TCF15	9	29	38	629.054
#362	ZNF175	9	27	36	609.817
#363	ZHX3	9	29	38	715.064
#364	RERE	9	30	39	2826.465
#365	MAFK	9	30	39	630.227
#366	LEF1	9	20	29	1703.673
#367	TCF3	9	24	33	467.914
#368	ZSCAN12	9	32	41	1170.594
#369	RCAN1	9	28	37	1235.111
#370	SRF	9	30	39	507.863
#371	HOXB8	9	30	39	1382.271
#372	PPARD	9	32	41	1201.414
#373	ZNF135	9	29	38	741.186
#374	FOXO3	9	20	29	709.892
#375	NR6A1	9	32	41	8620.722
#376	ZNF155	9	29	38	544.473
#377	RBPJL	9	25	34	1288.909
#378	SATB2	8	36	44	1304.256
#379	TRIM25	8	33	41	728.36
#380	FOXG1	8	29	37	722.899
#381	STAT2	8	24	32	176.093
#382	PITX2	8	32	40	1780.817
#383	CEBPE	8	21	29	594.408
#384	HIF3A	8	30	38	593.906
#385	NPAS1	8	31	39	1074.764
#386	NKX2-1	8	25	33	321.83
#387	TLX3	8	31	39	2614.394
#388	POU4F3	8	29	37	502.448
#389	PAX3	8	29	37	952.555
#390	LHX2	8	28	36	1370.337
#391	HOXA1	8	25	33	328.77
#392	ARID3A	8	31	39	840.106
#393	LZTS1	7	19	26	693.171
#394	POU1F1	7	38	45	913.994
#395	HESX1	7	25	32	992.523
#396	FOXD2	7	34	41	1038.788
#397	HOXC13	7	19	26	517.208
#398	ELK4	7	36	43	879.605
#399	TFDP2	7	24	31	178.847
#400	RFXAP	7	25	32	166.393
#401	DMRT1	7	32	39	649.538
#402	BATF3	7	25	32	256.87
#403	ZNF81	7	31	38	683.533
#404	ZFP37	7	22	29	328.159
#405	ATOH1	7	31	38	1342.572
#406	FOXB1	7	31	38	437.706
#407	SALL1	7	28	35	1175.936
#408	TCF21	7	25	32	594.597
#409	CREBBP	7	27	34	634.245
#410	ZNF323	7	20	27	774.412
#411	ZNF238	7	30	37	598.187
#412	HIC1	7	35	42	410.269
#413	HOXA10	7	25	32	912.301
#414	EMX1	7	29	36	345.924
#415	IRX4	7	20	27	307.493
#416	IRF5	7	31	38	954.031
#417	EGR3	7	15	22	111.456
#418	POU2F3	7	29	36	953.834
#419	POU3F3	7	35	42	1189.897
#420	TAF1B	7	22	29	1089.679
#421	HOXD3	6	33	39	677.951
#422	ALX3	6	21	27	206.847
#423	NFATC4	6	41	47	968.178
#424	VTN	6	29	35	475.167
#425	DLX6	6	28	34	1660.793
#426	FOXD3	6	30	36	787.868
#427	SOX15	6	26	32	576.046
#428	SOX30	6	38	44	963.895
#429	TBX1	6	38	44	737.902
#430	TAF13	6	32	38	481.652
#431	BARX1	6	21	27	354.261
#432	NPAS2	6	30	36	595.128
#433	DBP	6	36	42	566.572
#434	ARNT	6	21	27	1078.404
#435	KLF4	6	27	33	495.265
#436	ZEB1	6	23	29	304.036
#437	HOXD9	6	34	40	686.891
#438	FOXP3	6	35	41	817.132
#439	VDR	6	28	34	598.678
#440	PAX4	6	35	41	505.581
#441	HLF	6	26	32	382.363
#442	FOXA2	6	27	33	763.252
#443	ZNF134	6	26	32	250.944
#444	PPARG	6	17	23	437.674
#445	SP1	6	27	33	338.357
#446	PKNOX1	5	32	37	713.857
#447	IRF4	5	38	43	928.587
#448	HOXD13	5	27	32	261.085
#449	FOXD1	5	20	25	247.493
#450	PAX6	5	17	22	128.064
#451	ZFP36L1	5	26	31	1035.633
#452	SRY	5	33	38	351.381
#453	TSC22D3	5	28	33	78.736
#454	TCF12	5	35	40	1421.542
#455	GCM1	5	31	36	285.659
#456	NR4A1	5	23	28	511.598
#457	ZNF3	5	33	38	433.228
#458	THRA	5	19	24	489.824
#459	DLX2	5	28	33	227.559
#460	SIM1	5	24	29	278.82
#461	PAX5	5	36	41	1419.385
#462	MNX1	5	36	41	750.793
#463	CUX2	5	31	36	1584.513
#464	ERF	4	30	34	355.023
#465	MYCN	4	33	37	198.894
#466	POU4F1	4	21	25	341.093
#467	MSC	4	33	37	892.573
#468	PTH	4	33	37	327.497
#469	CREM	4	34	38	903.768
#470	POU3F1	4	28	32	202.28
#471	ZNF643	4	32	36	713.52
#472	HNF4G	4	27	31	244.066
#473	ZNF236	4	37	41	634.417
#474	PLAG1	4	33	37	200.4
#475	MYT1L	4	36	40	1447.168
#476	ZNF167	4	34	38	392.929
#477	MYCL1	4	31	35	290.906
#478	GBX2	4	28	32	764.784
#479	RB1	4	35	39	458.137
#480	SCAND2	3	35	38	429.893
#481	NFATC1	3	36	39	749.442
#482	ELK1	3	27	30	199.972
#483	ASCL1	3	22	25	393.397
#484	ZNF500	3	25	28	495.424
#485	YY1	3	22	25	45.151
#486	POU6F2	3	30	33	409.78
#487	FOXL2	3	27	30	74.703
#488	CREB5	3	21	24	92.795
#489	MYF5	3	34	37	440.061
#490	ETV4	2	37	39	753.149
#491	SCML1	2	28	30	130.25
#492	HEY1	2	23	25	416.674
#493	GSC2	2	34	36	762.883
#494	ZNF157	2	31	33	125.779
#495	ZNF639	2	34	36	837.447
#496	SOX2	2	31	33	181.733
#497	NR5A2	2	31	33	144.415
#498	RARB	1	38	39	40.599
#499	WT1	1	37	38	293.429
#500	PAX8	1	32	33	21.231