Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SOX15	79	1	80	33.031
#2	ZNF3	50	0	50	0
#3	HIC1	48	4	52	2567.75
#4	MNX1	47	2	49	152.834
#5	TRIM28	46	1	47	51.064
#6	HMGA1	46	0	46	0
#7	HNF1B	45	2	47	138.092
#8	TAF10	43	2	45	64.362
#9	HNRNPAB	40	6	46	2264.368
#10	NFE2L2	40	3	43	755.747
#11	ZSCAN29	39	6	45	1964.303
#12	DRAP1	39	6	45	688.291
#13	ESRRA	38	5	43	976.139
#14	RUNX3	38	3	41	307.537
#15	CNBP	37	4	41	233.521
#16	RFXAP	37	5	42	851.381
#17	GTF2H4	37	5	42	1296.208
#18	MAFG	36	3	39	598.094
#19	ZNF207	36	10	46	3071.216
#20	IKZF4	36	6	42	5206.879
#21	IRF3	36	2	38	1176.956
#22	ZBTB25	35	5	40	2396.197
#23	HOXB3	35	3	38	710.373
#24	CEBPD	35	5	40	2738.167
#25	FOXM1	35	5	40	387.101
#26	SLC2A4RG	35	2	37	1342.608
#27	NFKB2	34	3	37	74.266
#28	RXRA	33	4	37	509.193
#29	PBX3	33	9	42	2449.619
#30	TCF25	33	5	38	5388.571
#31	MGA	31	4	35	12991.664
#32	AHCTF1	31	3	34	11431.296
#33	C5orf41	31	4	35	276.433
#34	HEY1	30	4	34	526.577
#35	GTF2I	30	1	31	46.726
#36	TSC22D3	29	7	36	2166.462
#37	MTA1	28	7	35	867.184
#38	HNF4G	28	6	34	287.92
#39	MAFF	28	8	36	2179.525
#40	TAF12	28	13	41	1812.4
#41	MLL	27	11	38	561.517
#42	XBP1	27	5	32	303.673
#43	ZNF277	27	9	36	2508.44
#44	CREB5	27	8	35	580.9
#45	HMGB1	27	6	33	2939.515
#46	NOLC1	26	7	33	1576.158
#47	MLLT10	25	8	33	2681.758
#48	SP4	25	7	32	1129.193
#49	MEF2C	25	3	28	1065.281
#50	CSRNP1	25	4	29	186.854
#51	ZNF639	25	5	30	748.846
#52	ATF1	25	13	38	1596.747
#53	TP53	25	6	31	4991.754
#54	TFEB	25	4	29	838.702
#55	PRDM1	24	5	29	887.663
#56	NR3C1	24	15	39	5875.61
#57	SPEN	24	6	30	1320.35
#58	POU2F2	24	9	33	2179.836
#59	STAT1	24	10	34	2755.452
#60	JUND	24	6	30	2745.732
#61	IRF4	23	6	29	2083.079
#62	HMX2	23	13	36	1330.918
#63	RBPJ	23	7	30	1892.582
#64	YEATS4	23	5	28	116.585
#65	PURB	23	13	36	5649.565
#66	CBFB	23	4	27	1125.065
#67	HOXB4	22	7	29	3500.26
#68	ZFPM1	22	4	26	87.859
#69	TCF7	22	10	32	3785.978
#70	SREBF2	22	7	29	1494.543
#71	ZNF367	21	11	32	3468.871
#72	ZEB1	21	6	27	3457.966
#73	REL	21	8	29	1659.82
#74	CREB3L2	21	6	27	484.835
#75	IRF7	21	9	30	1193.679
#76	TBX15	21	10	31	941.079
#77	GABPB1	21	13	34	1454.384
#78	ETV5	21	10	31	930.035
#79	ZNF256	21	12	33	723.46
#80	TGIF2	21	11	32	3695.202
#81	FLI1	21	7	28	650.745
#82	HHEX	21	12	33	615.993
#83	TCF3	21	4	25	65.639
#84	REST	21	12	33	2226.325
#85	KLF6	20	9	29	1474.031
#86	RELA	20	5	25	1188.073
#87	ZFP36L2	20	8	28	248.68
#88	MTF1	20	9	29	2454.948
#89	NFE2L1	20	10	30	7974.486
#90	RCAN1	20	12	32	810.578
#91	EBF1	19	10	29	3021.899
#92	ZNF281	19	6	25	1513.297
#93	SPIB	19	10	29	1165.95
#94	LASS6	19	7	26	924.715
#95	UHRF1	19	5	24	594.213
#96	ARID4A	19	10	29	1486.872
#97	MEF2A	19	14	33	16294.774
#98	TSC22D4	19	13	32	6868.637
#99	ARNTL2	19	7	26	419.731
#100	TFCP2	19	8	27	391.79
#101	SOLH	19	6	25	415.849
#102	BHLHE40	19	15	34	1850.837
#103	C11orf9	19	12	31	2143.097
#104	RERE	19	6	25	1429.921
#105	ETV4	19	10	29	957.779
#106	PA2G4	18	3	21	85.843
#107	HES1	18	14	32	8894.682
#108	E2F6	18	10	28	2563.73
#109	TEAD2	18	2	20	14.902
#110	PLSCR1	18	8	26	921.56
#111	USF2	18	9	27	235.12
#112	ZBTB38	18	10	28	901.963
#113	CREBZF	18	10	28	1582.885
#114	CLOCK	18	12	30	1532.659
#115	PRRX1	18	12	30	4349.717
#116	HOXB2	18	6	24	1290.748
#117	BLZF1	18	13	31	1932.826
#118	LHX2	17	22	39	28568.681
#119	AFF1	17	7	24	423.537
#120	IRF8	17	11	28	1579.286
#121	DBP	17	13	30	1338.404
#122	TCFL5	17	12	29	1457.768
#123	ZBTB48	17	8	25	2379.097
#124	ZFP90	17	6	23	1230.845
#125	NFYA	17	5	22	375.648
#126	NFIB	17	8	25	936.122
#127	E2F8	17	11	28	5526.938
#128	PURA	17	8	25	299.598
#129	ZNF397	17	10	27	4747.671
#130	PLAGL2	17	17	34	6099.247
#131	TRIM22	17	14	31	1300.594
#132	CCRN4L	17	12	29	3406.407
#133	MBD1	16	11	27	1863.113
#134	ZKSCAN1	16	9	25	1413.969
#135	JUNB	16	7	23	545.747
#136	TFAP2B	16	8	24	1011.801
#137	BCL3	16	11	27	1846.755
#138	KDM5B	16	10	26	1115.707
#139	KLF7	16	11	27	3678.194
#140	ATF7	16	18	34	1200.397
#141	BACH1	16	8	24	1512.925
#142	CREB1	16	7	23	123.604
#143	ZNF238	16	11	27	1786.576
#144	NR1H2	16	9	25	335.393
#145	RBCK1	15	10	25	496.094
#146	STAT2	15	10	25	994.776
#147	HMG20B	15	8	23	1972.101
#148	IKZF3	15	9	24	22529.851
#149	E2F2	15	11	26	939.01
#150	GLIS3	15	15	30	1786.765
#151	BATF	15	17	32	1614.376
#152	PGBD1	15	13	28	2325.967
#153	FOXG1	15	17	32	5663.195
#154	MSX1	15	11	26	309.227
#155	FUBP1	15	14	29	1472.726
#156	GLIS2	15	17	32	3262.074
#157	UBN1	14	7	21	395.482
#158	CREB3L4	14	13	27	1006.856
#159	TSC22D2	14	16	30	1727.911
#160	FBXW7	14	17	31	755.807
#161	CSRNP2	14	11	25	2927.804
#162	LCOR	13	15	28	976.653
#163	RORA	13	16	29	1646.714
#164	STAT4	13	15	28	2600.223
#165	EGR3	13	8	21	741.545
#166	NR1D2	13	10	23	2568.909
#167	SMAD6	13	7	20	4106.939
#168	TADA3	13	8	21	5545.296
#169	RB1	13	10	23	2039.936
#170	FOXP2	13	11	24	1410.229
#171	IRF9	13	14	27	1358.963
#172	CREB3L1	13	18	31	5951.874
#173	JDP2	13	21	34	3641.554
#174	NFAT5	13	9	22	11776.55
#175	SP1	13	10	23	1049.401
#176	SIN3A	13	13	26	1891.09
#177	ARNTL	13	16	29	4944.73
#178	GATAD2B	13	5	18	786.369
#179	ATF2	13	5	18	1266.772
#180	KLF10	13	12	25	4219.845
#181	MEOX1	13	13	26	7115.04
#182	NFIL3	13	17	30	906.138
#183	ZNF232	13	17	30	1359.901
#184	RXRB	12	10	22	348.539
#185	KLF3	12	20	32	2025.795
#186	STAT5A	12	9	21	1787.981
#187	ELK1	12	11	23	1833.908
#188	ZNF498	12	13	25	2541.343
#189	SMAD5	12	10	22	1952.76
#190	CITED2	12	7	19	625.499
#191	GAS7	12	14	26	1582.029
#192	PBX4	12	19	31	901.41
#193	NFATC3	12	11	23	5272.621
#194	SNAPC2	12	10	22	2329.015
#195	RUNX1	12	14	26	3535.675
#196	ELF1	12	14	26	3383.579
#197	ELF2	12	9	21	572.537
#198	ZSCAN16	12	15	27	625.23
#199	KLF9	12	11	23	2180.9
#200	SALL2	12	14	26	1709.653
#201	FOXO4	12	8	20	147.285
#202	STAT6	11	9	20	1528.34
#203	ZNF91	11	10	21	651.618
#204	RELB	11	8	19	493.254
#205	ZHX2	11	10	21	201.858
#206	TFDP1	11	8	19	2178.457
#207	TP73	11	22	33	2628.342
#208	POU3F1	11	16	27	3508.775
#209	NFIC	11	8	19	680.111
#210	SLC30A9	11	16	27	1562.723
#211	E2F7	11	20	31	3750.128
#212	ZNF496	11	14	25	1157.951
#213	HOXC4	11	17	28	4163.207
#214	SOX9	11	19	30	1307.032
#215	HOXB7	11	12	23	505.904
#216	ZGPAT	11	9	20	872.393
#217	ASCL1	11	18	29	3780.404
#218	ZNF643	11	18	29	850.375
#219	ELK3	11	15	26	985.388
#220	EPAS1	11	19	30	1544.414
#221	HSF2	11	7	18	1244.472
#222	AHR	11	17	28	1001.938
#223	TAF5L	11	15	26	567.704
#224	KLF16	11	10	21	346.927
#225	FOXP4	10	11	21	805.568
#226	GTF2IRD1	10	16	26	530.935
#227	ZNF133	10	9	19	1647.361
#228	ADNP2	10	10	20	873.145
#229	LMO4	10	11	21	2601.835
#230	FOSL2	10	13	23	521.72
#231	NFE2L3	10	15	25	574.564
#232	SUPT6H	10	5	15	606.756
#233	PCGF2	10	13	23	1247.328
#234	RCOR1	10	14	24	1206.389
#235	ZKSCAN4	10	9	19	360.927
#236	SIX1	10	7	17	1217.757
#237	CREM	10	14	24	542.518
#238	PPARA	10	12	22	566.814
#239	MLXIPL	10	9	19	5987.354
#240	GTF2H2	10	14	24	1099.147
#241	HCFC1	10	10	20	576.407
#242	TP63	10	16	26	1817.971
#243	SIX3	10	12	22	2629.038
#244	ZNF134	10	6	16	3082.109
#245	CUX1	10	16	26	1201.694
#246	MXD1	9	11	20	494.437
#247	MEIS3P1	9	14	23	396.559
#248	SPI1	9	9	18	952.648
#249	NPAT	9	13	22	1651.46
#250	ATF3	9	10	19	3161.449
#251	E2F5	9	16	25	1959.196
#252	CBL	9	14	23	10454.261
#253	HOPX	9	20	29	2920.373
#254	CSDA	9	10	19	184.831
#255	MYPOP	9	14	23	2277.915
#256	HMGA2	9	11	20	2157.167
#257	MEF2D	9	8	17	4837.917
#258	MEIS2	9	24	33	2513.913
#259	FOXJ1	9	12	21	3153.866
#260	MYBL2	9	9	18	279.182
#261	NR2F2	9	14	23	3471.892
#262	TAF5	9	16	25	827.2
#263	TCF19	9	7	16	1862.681
#264	ZNF217	9	11	20	1347.772
#265	FOXN2	9	16	25	1969.214
#266	EGR2	8	16	24	1868.72
#267	ZNF187	8	18	26	768.636
#268	MAFK	8	16	24	4622.028
#269	E2F3	8	14	22	1918.036
#270	SPDEF	8	12	20	653.63
#271	BATF3	8	19	27	663.624
#272	ZHX1	8	7	15	90.753
#273	ZFHX3	8	18	26	1354.163
#274	EOMES	8	14	22	1312.637
#275	TSHZ2	8	10	18	2937.325
#276	TFAM	8	10	18	559.616
#277	ERF	8	10	18	114.542
#278	EMX1	8	18	26	2599.34
#279	ELK4	8	16	24	2076.993
#280	E2F1	8	10	18	2219.497
#281	ZSCAN18	8	14	22	344.449
#282	FOXO1	8	13	21	749.076
#283	PBX2	8	7	15	895.591
#284	SOX12	8	17	25	1688.21
#285	EGR1	8	13	21	4501.526
#286	CEBPB	8	11	19	7569.643
#287	ZNF92	8	13	21	4533.126
#288	SOX4	8	12	20	1006.678
#289	ZFP36L1	8	9	17	110.965
#290	IRF1	8	15	23	912.641
#291	GATA3	7	20	27	3928.449
#292	ZNF500	7	11	18	1319.54
#293	TSHZ1	7	6	13	135.375
#294	NR4A1	7	9	16	1347.585
#295	SP3	7	16	23	3262.799
#296	NEUROD1	7	4	11	354.731
#297	TULP4	7	16	23	1346.354
#298	SP140	7	15	22	737.425
#299	STAT3	7	9	16	1196.533
#300	NFATC2	7	16	23	1196.515
#301	ZNF167	7	16	23	524.162
#302	POU2F1	7	17	24	590.761
#303	JUN	7	13	20	546.833
#304	NR2C2	7	14	21	1164.301
#305	ARNT	7	15	22	149.198
#306	ZNF165	7	19	26	709.459
#307	E2F4	7	15	22	438.089
#308	TCF12	7	11	18	848.398
#309	TRPS1	7	18	25	1773.468
#310	FOSL1	7	14	21	625.33
#311	PPARD	7	11	18	285.858
#312	HOXB6	7	9	16	295.42
#313	NFATC1	7	10	17	1435.53
#314	RFX1	7	13	20	260.548
#315	IRF2	6	10	16	6177.776
#316	FOXP1	6	19	25	1483.629
#317	SMAD1	6	17	23	278.887
#318	SREBF1	6	11	17	2332.965
#319	BTG2	6	12	18	1206.388
#320	YY1	6	10	16	662.976
#321	TCF15	6	6	12	871.07
#322	CBFA2T3	6	15	21	383.87
#323	CBFA2T2	6	12	18	2006.92
#324	ZSCAN2	6	21	27	1065.138
#325	CNOT7	6	6	12	160.93
#326	FOXN3	6	14	20	1564.031
#327	ARID3A	6	8	14	56.263
#328	ZNF132	6	16	22	1903.23
#329	TRIM25	6	13	19	832.013
#330	MTA3	6	18	24	3047.167
#331	HEY2	6	16	22	1013.46
#332	GATAD2A	6	12	18	1015.155
#333	NOTCH1	6	17	23	4716.504
#334	PHF5A	6	10	16	394.294
#335	ZNF175	6	19	25	967.634
#336	ZNF138	6	14	20	1501.056
#337	ZNF155	5	16	21	491.907
#338	FOS	5	8	13	306.648
#339	ZNF131	5	14	19	848.113
#340	ZNF215	5	18	23	1844.584
#341	MSRB2	5	10	15	160.657
#342	HSF1	5	11	16	2130.808
#343	ETS1	5	11	16	1621.59
#344	ZNF268	5	9	14	302.065
#345	MSC	5	10	15	2505.578
#346	POU6F1	5	8	13	84.631
#347	ALS2CR8	5	16	21	652.435
#348	TRERF1	5	21	26	1205.79
#349	SIX5	5	11	16	551.105
#350	FOXO3	5	18	23	1204.338
#351	BCL6	5	14	19	1584.686
#352	WT1	5	12	17	835.029
#353	NFATC4	5	17	22	654.19
#354	MAX	5	12	17	160.751
#355	SCML1	5	23	28	2177.659
#356	ZNF174	5	10	15	89.155
#357	ZNF83	5	11	16	705.8
#358	ZNF193	5	10	15	923.851
#359	ZNF628	5	15	20	540.552
#360	HOXA1	5	15	20	2362.67
#361	PRDM2	5	9	14	386.589
#362	HMBOX1	5	9	14	744.419
#363	MLX	5	17	22	2085.105
#364	ATF6B	5	13	18	1154.028
#365	NR4A3	5	10	15	952.757
#366	TFE3	5	11	16	2574.187
#367	ZNF41	5	13	18	1182.212
#368	HSF5	5	20	25	1698.339
#369	TARDBP	5	13	18	290.98
#370	ETV7	5	17	22	1178.547
#371	HDX	4	18	22	1954.382
#372	TAF4B	4	17	21	1998.789
#373	TBX21	4	24	28	1077.894
#374	ETV6	4	20	24	2674.97
#375	AEBP1	4	11	15	492.312
#376	LEF1	4	20	24	3656.233
#377	KLF11	4	15	19	219.671
#378	ELF3	4	17	21	664.278
#379	ZNF117	4	17	21	570.435
#380	ATF5	4	15	19	271.664
#381	ZNF202	4	11	15	1570.33
#382	WNT5A	4	27	31	1590.654
#383	HOXC8	4	7	11	1371.614
#384	NR4A2	4	9	13	500.265
#385	PLAG1	4	18	22	1497.428
#386	ZRANB2	4	17	21	661.154
#387	MYC	4	10	14	792.943
#388	ZXDA	4	12	16	528.913
#389	PITX2	4	12	16	181.536
#390	GATAD1	4	16	20	456.153
#391	MEOX2	4	9	13	116.524
#392	DLX2	4	8	12	161.341
#393	ZNF24	4	12	16	421.726
#394	ISL2	4	15	19	1457.846
#395	KLF2	4	22	26	568.566
#396	PHF1	4	12	16	658.726
#397	TFEC	4	13	17	188.206
#398	SOX5	4	10	14	200.071
#399	TAF1B	3	13	16	488.023
#400	PITX1	3	17	20	251.405
#401	SCAND1	3	26	29	2896.528
#402	SOX6	3	9	12	855.127
#403	TCF4	3	11	14	1924.748
#404	ZNF71	3	14	17	168.086
#405	HOXA9	3	15	18	652.392
#406	CSRNP3	3	13	16	2435.335
#407	HESX1	3	18	21	993.232
#408	SRF	3	10	13	460.559
#409	FOXJ3	3	14	17	365.206
#410	BHLHE41	3	18	21	652.644
#411	L3MBTL4	3	19	22	992.584
#412	ZNF394	3	15	18	223.154
#413	AFF4	3	10	13	1281.073
#414	ZXDC	3	13	16	352.146
#415	SCAND3	3	18	21	651.097
#416	ZNF434	3	8	11	109.574
#417	DDIT3	3	9	12	599.223
#418	PHTF1	3	10	13	555.821
#419	KLF5	3	23	26	564.025
#420	STAT5B	3	17	20	1101.12
#421	SMAD2	3	11	14	460.62
#422	MSL3	3	14	17	253.527
#423	NFYC	3	6	9	432.647
#424	PPARG	3	17	20	667.49
#425	FOXO6	3	13	16	2730.328
#426	TEAD1	3	17	20	943.214
#427	ZNF70	3	11	14	501.706
#428	SNAPC4	3	10	13	77.979
#429	SMAD3	3	14	17	1195.301
#430	T	3	18	21	1144.487
#431	MZF1	3	16	19	738.493
#432	VDR	3	18	21	521.237
#433	IKZF1	3	17	20	345.13
#434	TSC22D1	3	19	22	2658.549
#435	ZSCAN5A	3	17	20	965.91
#436	ZNF169	3	14	17	2186.039
#437	NFX1	3	14	17	282.377
#438	ENO1	2	11	13	164.82
#439	ZNF75D	2	13	15	191.045
#440	SMAD4	2	12	14	574.339
#441	ATF6	2	17	19	167.736
#442	TAF13	2	14	16	2153.509
#443	ZNF438	2	12	14	40.544
#444	FOXA3	2	17	19	317.994
#445	BATF2	2	14	16	225.669
#446	C2orf3	2	14	16	598.849
#447	KLF12	2	18	20	704.05
#448	GCFC1	2	13	15	1129.196
#449	ISX	2	22	24	279.324
#450	ZNF19	2	8	10	136.563
#451	RFX3	2	15	17	233.914
#452	RUNX2	2	18	20	973.184
#453	NR2F6	2	21	23	108.093
#454	ZNF148	2	13	15	324.602
#455	TFDP2	2	19	21	228.269
#456	TADA2A	2	16	18	166.717
#457	HOXA2	2	22	24	523.47
#458	ZKSCAN2	2	17	19	1331.688
#459	ZNF37A	2	15	17	165.328
#460	SCMH1	2	16	18	2844.595
#461	ETS2	2	8	10	61.999
#462	MYCL1	2	14	16	332.549
#463	BCL11B	2	17	19	1699.977
#464	TGIF1	2	12	14	195.055
#465	MYF6	2	8	10	245.277
#466	POU2F3	2	13	15	717.855
#467	POU4F1	1	11	12	51.089
#468	ETV2	1	13	14	176.983
#469	PEG3	1	12	13	95.007
#470	TFAP4	1	17	18	5736.771
#471	ZNF93	1	13	14	44.875
#472	NR2C1	1	13	14	1265.799
#473	DMRT1	1	15	16	545.698
#474	IRF5	1	17	18	1299.057
#475	ZNF323	1	13	14	26.94
#476	STRN3	1	21	22	19008.843
#477	ZSCAN21	1	12	13	248.78
#478	SATB1	1	13	14	590.716
#479	KDM5A	1	10	11	14.865
#480	MTA2	1	14	15	410.168
#481	PKNOX1	1	16	17	87.572
#482	TEF	1	15	16	144.49
#483	CDKN2A	1	13	14	77.274
#484	ZNF274	1	22	23	77.263
#485	ZFP37	1	17	18	2552.899
#486	ZNF85	1	17	18	115.005
#487	C1orf85	1	12	13	253.974
#488	TEAD4	0	23	23	0
#489	ESR2	0	18	18	0
#490	USF1	0	9	9	0
#491	FOXK2	0	12	12	0
#492	RARA	0	16	16	0
#493	HES6	0	17	17	0
#494	TBX1	0	15	15	0
#495	PAX8	0	18	18	0
#496	NR1H3	0	18	18	0
#497	CTBP1	0	23	23	0
#498	CTNNB1	0	14	14	0
#499	NR1I2	0	14	14	0
#500	ZNF33A	0	16	16	0