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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	RXRB	50	2	52	279.624
#2	IKZF1	45	5	50	67.216
#3	BTG2	44	2	46	19.347
#4	RB1	44	8	52	151.653
#5	TEAD2	41	10	51	845.901
#6	HOPX	41	10	51	1069.399
#7	MEOX2	40	6	46	1456.345
#8	MAX	40	1	41	260.454
#9	EHF	39	6	45	909.073
#10	TCF3	39	6	45	146.79
#11	NFATC1	38	12	50	524.085
#12	ZNF117	38	10	48	300.851
#13	SMAD3	36	8	44	202.641
#14	PBX4	36	7	43	1780.064
#15	TFE3	35	10	45	751.491
#16	GATA3	35	9	44	749.242
#17	ZNF92	35	15	50	422.203
#18	BCL6	34	10	44	1049.258
#19	SP1	34	7	41	136.093
#20	NR2F1	34	10	44	1343.404
#21	ETV6	33	12	45	1374.139
#22	FOXQ1	33	6	39	511.553
#23	NPAS2	33	9	42	598.051
#24	ZFP36L2	32	3	35	2243.837
#25	ZSCAN10	32	14	46	1651.816
#26	STAT1	31	6	37	857.422
#27	BCL3	31	14	45	466.709
#28	FOXC1	31	14	45	868.513
#29	PROX1	31	12	43	998.691
#30	HMGA1	30	12	42	814.202
#31	IRX3	30	9	39	696.836
#32	FOXM1	30	6	36	279.413
#33	SMAD1	30	7	37	367.868
#34	ZKSCAN3	30	10	40	1041.15
#35	NFIX	30	10	40	1109.49
#36	ZNF238	29	9	38	753.265
#37	HLF	29	13	42	1426.653
#38	TSHZ2	28	19	47	1363.14
#39	SOX9	28	9	37	584.659
#40	EVX1	28	14	42	1411.869
#41	KLF5	28	10	38	432.296
#42	SOX4	28	11	39	1006.781
#43	TP53	27	9	36	5400.96
#44	ARNT	27	14	41	924.827
#45	THRB	27	17	44	1421.832
#46	TRIM29	27	7	34	264.578
#47	HOXB1	26	14	40	1170.075
#48	LEF1	26	20	46	1186.413
#49	BNC1	26	18	44	1642.018
#50	GLIS3	26	20	46	1270.112
#51	ATF2	26	16	42	797.819
#52	TWIST2	26	13	39	1426.5
#53	HOXC10	26	11	37	894.25
#54	HOXC9	26	11	37	1096.396
#55	ESRRB	26	14	40	1148.569
#56	TFAP2C	26	9	35	493.185
#57	PKNOX1	25	15	40	877.365
#58	HOXA9	25	9	34	794.345
#59	HOXC12	25	10	35	817.428
#60	STAT5B	25	15	40	1178.41
#61	SOX8	25	8	33	281.895
#62	GATA4	25	15	40	1215.528
#63	SUPT6H	25	14	39	661.544
#64	CREB3L1	25	17	42	1677.175
#65	TBX3	25	14	39	1086.981
#66	CRX	25	13	38	1169.312
#67	AHCTF1	25	13	38	440.718
#68	ZBTB17	25	11	36	269.211
#69	E2F8	25	9	34	247.426
#70	GRHL3	24	10	34	604.105
#71	MLXIPL	24	16	40	1208.313
#72	HESX1	24	16	40	1162.537
#73	CREM	24	18	42	1707.231
#74	TSC22D1	24	14	38	1268.613
#75	NKX2-3	24	12	36	684.175
#76	FOSL2	24	17	41	1248.71
#77	RUNX1T1	24	18	42	1330.181
#78	TSC22D2	24	21	45	1114.669
#79	TGIF1	24	17	41	1136.044
#80	FUBP1	23	13	36	497.623
#81	FOXG1	23	17	40	869.781
#82	SIX2	23	15	38	1487.09
#83	RELA	23	18	41	981.83
#84	ZBTB38	23	13	36	1138.66
#85	IRF5	23	16	39	557.237
#86	SOX10	23	18	41	1191.307
#87	NR2F2	22	16	38	1137.576
#88	HOXD4	22	24	46	1796.509
#89	PBX3	22	14	36	1016.318
#90	LHX2	22	25	47	1432.533
#91	ELK4	22	13	35	1119.927
#92	ZNF3	22	15	37	1249.81
#93	KLF3	22	14	36	1159.569
#94	ZNF135	22	11	33	340.907
#95	MEIS1	22	15	37	838.649
#96	NR4A3	22	12	34	719.644
#97	FOXE3	22	15	37	1308.785
#98	YY1	22	18	40	542.79
#99	STAT2	22	11	33	131.044
#100	HMG20B	22	13	35	848.956
#101	TFAP2A	21	10	31	577.971
#102	TFAP4	21	12	33	678.106
#103	KLF4	21	14	35	1059.918
#104	FOXK1	21	13	34	973.235
#105	FOXD2	21	19	40	1722.621
#106	ISX	21	18	39	1442.534
#107	AR	21	13	34	3560.269
#108	PHTF1	21	18	39	1166.168
#109	NEUROD2	21	15	36	1091.298
#110	ZIC2	21	16	37	1330.436
#111	HSF2	20	14	34	426.636
#112	ATF7	20	11	31	567.401
#113	CUX2	20	16	36	1160.406
#114	PAX5	20	11	31	549.806
#115	POU3F3	20	12	32	1113.279
#116	SOX17	20	12	32	711.867
#117	TP63	20	13	33	923.272
#118	SOX2	20	19	39	1022.587
#119	WNT5A	20	25	45	1553.463
#120	PITX1	20	10	30	395.125
#121	POU4F1	20	12	32	618.259
#122	NFIB	20	17	37	1454.4
#123	IRX4	19	14	33	705.358
#124	KLF11	19	12	31	601.755
#125	LHX8	19	18	37	1279.408
#126	LHX1	19	16	35	906.222
#127	CREBZF	19	16	35	1237.999
#128	TEAD4	19	18	37	1429.672
#129	IRX5	19	14	33	932.666
#130	HOXA5	19	13	32	550.859
#131	FOXP3	19	12	31	358.351
#132	GBX2	19	18	37	1212.146
#133	CBL	19	15	34	846.74
#134	CEBPD	19	10	29	565.178
#135	FOXA1	19	20	39	1164.08
#136	MLLT10	19	15	34	1036.265
#137	NR4A2	19	8	27	417.328
#138	NFAT5	19	15	34	702.834
#139	HOXA11	19	22	41	1210.872
#140	PBX1	19	16	35	670.857
#141	TGIF2LY	18	21	39	1333.623
#142	CSRNP3	18	17	35	1047.715
#143	ZNF174	18	13	31	658.041
#144	HOXA13	18	23	41	1068.998
#145	SIX1	18	21	39	919.276
#146	TCF20	18	17	35	1154.299
#147	FOXP1	18	16	34	863.281
#148	SOX30	18	14	32	757.213
#149	CLOCK	18	16	34	1039.474
#150	LMO4	18	20	38	896.935
#151	STRN3	18	16	34	770.211
#152	RARA	18	16	34	803.798
#153	PPARA	18	18	36	930.009
#154	ATF3	18	8	26	369.883
#155	TFCP2L1	18	23	41	1198.473
#156	NFIA	18	15	33	1042.068
#157	OVOL1	18	16	34	3845.588
#158	ZEB2	18	20	38	1159.704
#159	TADA2A	18	14	32	760.376
#160	HOXA7	18	14	32	574.364
#161	FOSL1	18	16	34	1067.327
#162	TEF	18	17	35	1231.982
#163	TBX5	18	16	34	1394.384
#164	ZNF132	18	16	34	961.116
#165	BACH1	17	14	31	972.021
#166	HOXD13	17	20	37	1290.605
#167	SCAND2	17	18	35	913.82
#168	LASS6	17	16	33	934.716
#169	ATOH1	17	16	33	995.513
#170	ZIC5	17	14	31	864.123
#171	RERE	17	17	34	1191.195
#172	TRPS1	17	15	32	537.053
#173	PPBPL2	17	17	34	901.038
#174	NANOGNB	17	20	37	1324.355
#175	RARB	17	19	36	1002.932
#176	CSDA	17	19	36	948.008
#177	ZNF71	17	13	30	840.195
#178	ZNF90	17	16	33	908.331
#179	SCAND3	17	20	37	1361.316
#180	RFXAP	17	17	34	709.402
#181	CCRN4L	17	15	32	640.677
#182	VAX2	17	12	29	586.759
#183	NR2E1	17	12	29	645.118
#184	OLIG2	17	16	33	1166.156
#185	E2F2	17	13	30	1236.733
#186	ZNF131	17	18	35	833.174
#187	POU1F1	17	21	38	1178.832
#188	ZFHX3	17	17	34	835.102
#189	HAND1	17	18	35	948.114
#190	FOSB	17	9	26	444.803
#191	CDKN2A	17	18	35	833.382
#192	HMGB2	17	20	37	862.721
#193	FOXE1	17	20	37	1226.04
#194	SRY	17	15	32	836.962
#195	ERF	17	22	39	1189.587
#196	ESX1	17	15	32	778.997
#197	FOS	17	10	27	1052.022
#198	NFKB2	16	20	36	1175.458
#199	ARX	16	18	34	1399.643
#200	FOXD4	16	14	30	641.349
#201	MESP2	16	12	28	805.453
#202	ENO1	16	20	36	896.625
#203	ESRRG	16	19	35	1245.399
#204	ZSCAN1	16	16	32	714.013
#205	ASCL2	16	15	31	758.325
#206	SLC26A3	16	18	34	970.521
#207	ERG	16	12	28	600.952
#208	TFAP2D	16	16	32	837.263
#209	NR2F6	16	13	29	763.73
#210	MLX	16	16	32	784.932
#211	TCF21	16	16	32	802.789
#212	ALX3	16	18	34	1460.861
#213	GATAD2A	16	12	28	696.28
#214	NR1I2	16	18	34	1038.992
#215	ATF5	16	18	34	842.819
#216	TAF4	16	26	42	1015.081
#217	CEBPE	16	17	33	997.082
#218	GLI3	16	20	36	1839.283
#219	NFATC4	16	11	27	767.118
#220	FOXD3	16	20	36	936.025
#221	TLX2	16	16	32	1042.329
#222	MYCN	16	12	28	431.668
#223	HOXA3	16	18	34	987.44
#224	NKX3-2	16	20	36	838.73
#225	RORC	16	18	34	977.161
#226	IRF4	16	19	35	1595.551
#227	ASCL1	16	16	32	1254.599
#228	PAX7	16	17	33	944.615
#229	LMX1A	16	12	28	705.493
#230	PPARG	16	13	29	451.241
#231	MECOM	15	16	31	768.099
#232	BHLHE41	15	20	35	857.174
#233	ZNF85	15	21	36	1133.758
#234	BCL11B	15	19	34	787.137
#235	MYT1L	15	17	32	897.335
#236	ELF3	15	20	35	1669.102
#237	FOXR2	15	22	37	908.706
#238	CREB3L3	15	21	36	1071.847
#239	DMRT2	15	21	36	1197.766
#240	IRX1	15	18	33	1055.384
#241	MSX2	15	21	36	1194.968
#242	RORA	15	18	33	1030.493
#243	RARG	15	17	32	684.08
#244	EGR4	15	16	31	855.586
#245	HEY2	15	22	37	992.514
#246	PRDM2	15	16	31	903.427
#247	HIRA	15	18	33	785.889
#248	RUNX2	15	18	33	918.303
#249	KLF17	15	20	35	1056.452
#250	HOXD1	15	19	34	1060.202
#251	JUN	15	7	22	207.011
#252	TFDP3	15	19	34	991.095
#253	NR2E3	15	17	32	791.419
#254	SOX21	15	17	32	1072.952
#255	NPAS1	15	17	32	1043.929
#256	ZNF19	15	15	30	536.885
#257	GATAD1	15	15	30	949.043
#258	SIN3A	15	13	28	490.522
#259	TLX3	15	16	31	750.943
#260	HMX2	15	17	32	690.368
#261	IRX2	15	14	29	434.583
#262	EGR1	15	4	19	267.838
#263	SPIC	15	16	31	556.079
#264	DLX4	15	12	27	886.822
#265	MMP14	15	18	33	1565.299
#266	SOX18	15	19	34	1012.901
#267	ZNF169	15	11	26	559.167
#268	ZFP42	14	14	28	586.464
#269	MKX	14	14	28	675.246
#270	HOXD11	14	11	25	873.769
#271	NR3C2	14	15	29	561.228
#272	ZNF639	14	19	33	973.279
#273	IRF6	14	15	29	964.766
#274	FOXL2	14	17	31	822.295
#275	HOXB6	14	22	36	1154.167
#276	ZSCAN12	14	13	27	746.923
#277	SP3	14	15	29	716.517
#278	MYT1	14	21	35	1139.215
#279	KLF12	14	15	29	794.057
#280	ETV1	14	18	32	1021.114
#281	ESR1	14	18	32	1008.975
#282	SOX7	14	18	32	630.331
#283	NFATC2	14	17	31	790.353
#284	FOXA2	14	17	31	1124.622
#285	POU3F1	14	16	30	608.63
#286	ZSCAN4	14	17	31	875.165
#287	MTA2	14	19	33	473.125
#288	ZNF215	14	19	33	1103.498
#289	CREBBP	14	24	38	1067.517
#290	SMAD9	14	13	27	585.467
#291	CREB5	14	20	34	663.778
#292	ZNF449	14	13	27	517.964
#293	GSX1	14	12	26	442.36
#294	KLF1	14	19	33	968.649
#295	FOXL1	14	22	36	1211.094
#296	ZNF444	14	15	29	727.296
#297	FOXO1	14	21	35	941.061
#298	LHX4	14	20	34	1444.588
#299	NFE2L2	14	9	23	476.937
#300	MNX1	14	16	30	804.991
#301	HOXB8	14	16	30	506.965
#302	FOXN3	14	21	35	781.593
#303	NKX2-5	14	15	29	808.344
#304	ETS2	14	12	26	365.129
#305	RCAN1	14	16	30	754.914
#306	USF1	14	13	27	504.282
#307	ZSCAN20	14	17	31	928.434
#308	PITX2	14	17	31	686.862
#309	NANOG	14	16	30	678.805
#310	TRERF1	13	16	29	621.826
#311	HES6	13	22	35	846.364
#312	PHOX2A	13	16	29	730.626
#313	MYF6	13	12	25	500.592
#314	NKX6-1	13	17	30	880.421
#315	C2orf3	13	21	34	735.802
#316	HNF4G	13	26	39	910.89
#317	TBR1	13	23	36	1027.478
#318	HNRNPAB	13	15	28	810.169
#319	SCML1	13	15	28	503.67
#320	ZFP36L1	13	20	33	747.369
#321	L3MBTL4	13	18	31	603.494
#322	C12orf28	13	21	34	1013.954
#323	PCGF2	13	17	30	771.657
#324	DLX1	13	18	31	894.633
#325	FOXA3	13	19	32	960.537
#326	SOX6	13	22	35	955.597
#327	POU3F2	13	18	31	871.974
#328	FOXD1	13	24	37	817.43
#329	HOXD9	13	18	31	917.807
#330	HIC1	13	11	24	692.807
#331	TBX22	13	18	31	1019.588
#332	HOXC5	13	13	26	425.501
#333	NKX2-1	13	17	30	740.094
#334	TSC22D3	13	20	33	929.109
#335	HOXA10	13	14	27	372.285
#336	DLX2	13	10	23	478.845
#337	FOXO6	13	18	31	725.863
#338	ETV4	13	24	37	1755.546
#339	FOXC2	13	16	29	574.671
#340	ZFHX4	13	16	29	735.574
#341	SMAD2	13	18	31	737.146
#342	ELK1	13	21	34	623.867
#343	HES5	13	19	32	870.047
#344	HNF4A	13	15	28	606.753
#345	HIF3A	13	16	29	2165.114
#346	SOX13	13	18	31	1029.963
#347	ETV7	13	22	35	1103.541
#348	ZIC3	12	20	32	919.234
#349	PHOX2B	12	19	31	617.41
#350	ALS2CR8	12	15	27	769.414
#351	PDX1	12	23	35	1072.471
#352	C11orf9	12	18	30	730.636
#353	EPAS1	12	18	30	568.225
#354	ZNF483	12	20	32	980.085
#355	NEUROD1	12	21	33	1083.739
#356	TP73	12	18	30	784.499
#357	BARX1	12	13	25	455.707
#358	PKNOX2	12	13	25	388.633
#359	LASS5	12	21	33	725.769
#360	ZIC1	12	13	25	1754.462
#361	ISL2	12	28	40	1088.319
#362	KDM5B	12	13	25	431.923
#363	NCOR1	12	17	29	780.964
#364	MYNN	12	19	31	748.769
#365	JUND	12	16	28	586.982
#366	TBX6	12	18	30	747.953
#367	HNF1B	12	17	29	734.464
#368	ISL1	12	19	31	666.116
#369	GCM1	12	16	28	440.992
#370	NEUROG1	12	17	29	581.829
#371	AFF4	12	16	28	903.575
#372	ANKRD30A	12	20	32	874.541
#373	TULP4	12	15	27	607.427
#374	HCFC1	12	17	29	604.597
#375	SNAPC5	12	16	28	700.122
#376	SMAD4	12	19	31	819.122
#377	ZHX3	12	21	33	947.162
#378	FOXB1	12	16	28	688.93
#379	GATA5	11	13	24	709.794
#380	GSX2	11	11	22	421.492
#381	HOXB9	11	22	33	778.357
#382	HOXA2	11	19	30	763.193
#383	SIM1	11	23	34	726.433
#384	SIM2	11	21	32	694.201
#385	NR5A1	11	14	25	663.9
#386	MAFK	11	23	34	1020.549
#387	SLC2A4RG	11	22	33	1183.953
#388	MYCL1	11	16	27	682.362
#389	DLX6	11	21	32	1085.713
#390	LHX9	11	19	30	1067.481
#391	ZNF207	11	14	25	682.286
#392	POU2F3	11	23	34	985.249
#393	NR0B1	11	23	34	912.746
#394	AFF1	11	20	31	964.794
#395	NOBOX	11	16	27	545.566
#396	ELF5	11	25	36	765.821
#397	RORB	11	18	29	850.676
#398	ZNF175	11	18	29	1252.503
#399	MITF	11	27	38	1027.319
#400	TBX2	11	21	32	698.641
#401	DMBX1	11	21	32	1001.372
#402	DMRT1	11	19	30	907.161
#403	ZNF496	11	18	29	910.374
#404	WT1	11	22	33	826.756
#405	GLI2	11	17	28	824.485
#406	MIXL1	11	15	26	603.949
#407	TFAP2B	11	19	30	593.34
#408	NPAT	11	18	29	812.295
#409	ONECUT1	11	21	32	650.066
#410	TEAD1	11	20	31	815.033
#411	POU3F4	11	17	28	673.898
#412	MYF5	10	16	26	593.159
#413	MLL	10	19	29	570.447
#414	LZTS1	10	17	27	549.027
#415	MESP1	10	17	27	772.614
#416	POU6F2	10	17	27	527.973
#417	NR4A1	10	12	22	341.901
#418	HOXB7	10	19	29	577.915
#419	FOXH1	10	21	31	591.797
#420	ZSCAN2	10	17	27	694.283
#421	NR6A1	10	16	26	409.904
#422	FOXN4	10	18	28	576.075
#423	BRD8	10	15	25	559.605
#424	ALX4	10	18	28	633.313
#425	ETV2	10	17	27	632.788
#426	ZNF24	10	22	32	549.807
#427	ZNF287	10	23	33	1039.573
#428	SOX5	10	24	34	938.254
#429	NFIC	10	18	28	581.592
#430	MGA	10	24	34	1322.401
#431	ONECUT2	10	23	33	760.146
#432	CTBP1	10	16	26	889.778
#433	SIX3	10	13	23	430.298
#434	PURB	10	26	36	958.626
#435	GSC2	10	18	28	731.537
#436	ETV5	10	16	26	632.08
#437	ZNF167	10	21	31	765.122
#438	SCRT1	10	17	27	640.018
#439	SALL1	10	28	38	776.112
#440	SIX4	10	18	28	600.392
#441	HDX	10	17	27	422.068
#442	FOXP2	10	23	33	754.863
#443	HMGA2	9	21	30	641.159
#444	NKX6-2	9	22	31	817.094
#445	ESR2	9	15	24	311.537
#446	TAL1	9	17	26	541.209
#447	PAX3	9	22	31	634.571
#448	HOXA1	9	21	30	729.235
#449	PAX8	9	20	29	571.631
#450	SATB2	9	14	23	636.813
#451	PGR	9	18	27	413.939
#452	FOXI1	9	19	28	498.337
#453	ZNF80	9	19	28	697.694
#454	ZSCAN18	9	16	25	665.41
#455	ST18	9	20	29	512.062
#456	SOX1	9	16	25	479.784
#457	EN2	9	18	27	615.548
#458	NRL	9	21	30	643.404
#459	THRA	9	23	32	705.793
#460	FOXO3	8	16	24	774.97
#461	NR1I3	8	23	31	629.214
#462	TAF13	8	18	26	545.738
#463	ZNF396	8	23	31	792.105
#464	TBX1	8	22	30	484.823
#465	TBX20	8	24	32	723.987
#466	SMAD6	8	20	28	669.449
#467	HOXD3	8	20	28	474.493
#468	NR1H4	8	19	27	696.795
#469	RBPJL	8	9	17	212.332
#470	ZNF93	8	15	23	404.715
#471	ZFHX2	8	24	32	719.244
#472	VTN	8	22	30	838.434
#473	ZNF397	7	15	22	318.567
#474	VDR	7	21	28	583.858
#475	POU4F3	7	19	26	445.911
#476	KLF9	7	17	24	397.139
#477	GAS7	7	17	24	446.237
#478	PEG3	7	21	28	641.899
#479	PPARD	7	23	30	566.875
#480	ZNF81	7	23	30	456.391
#481	VSX1	6	29	35	472.247
#482	ZSCAN23	6	24	30	479.833
#483	BLZF1	6	15	21	300.733
#484	NR5A2	6	15	21	260.92
#485	TADA3	6	25	31	409.417
#486	PAX4	6	19	25	579.968
#487	MAF	6	24	30	644.277
#488	NFYA	6	23	29	485.62
#489	RUNX1	5	18	23	317.661
#490	PTH	5	18	23	326.61
#491	POU2F1	5	21	26	366.997
#492	PAX6	5	23	28	361.023
#493	SIX6	5	20	25	301.801
#494	PLSCR1	5	25	30	488.154
#495	POU4F2	4	18	22	262.015
#496	SEBOX	4	23	27	302.649
#497	OTX2	4	23	27	397.696
#498	ARNTL2	4	21	25	314.313
#499	REST	4	24	28	315.235
#500	FLI1	3	24	27	295.799