Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GTF2H4	37	4	41	839.377
#2	KLF7	30	3	33	976.678
#3	SCML2	29	7	36	1195.408
#4	IRF2	28	6	34	1215.468
#5	KLF9	27	10	37	2339.306
#6	LMO4	26	6	32	1110.682
#7	ENO1	26	5	31	1514.897
#8	TCF3	26	7	33	1780.334
#9	MGA	25	5	30	325.394
#10	ATF2	25	5	30	1281.826
#11	ADNP2	24	9	33	1441.394
#12	NFE2L1	24	9	33	1706.875
#13	ZFP36L2	24	7	31	1247.135
#14	RBCK1	24	9	33	1683.694
#15	KLF11	24	6	30	810.621
#16	HDAC2	23	7	30	957.303
#17	RELB	23	9	32	2235.439
#18	CSRNP3	23	3	26	547.245
#19	GLI3	22	6	28	2588.613
#20	GTF2H3	21	8	29	1268.097
#21	KDM5A	21	4	25	327.905
#22	ZNF189	21	11	32	1312.46
#23	TFDP1	21	5	26	565.021
#24	MAFF	21	8	29	1788.688
#25	ELF4	21	13	34	2056.41
#26	SOX10	20	13	33	3196.509
#27	ZNF140	20	5	25	608.78
#28	BCL3	20	9	29	1602.736
#29	BHLHE41	20	8	28	1516.479
#30	STAT2	20	11	31	1608.475
#31	LHX2	20	8	28	853.155
#32	STAT5A	20	6	26	1909.075
#33	E2F6	20	8	28	2570.39
#34	NFYA	19	14	33	1567.566
#35	ZNF232	19	6	25	410.414
#36	ATF1	19	6	25	831.846
#37	CNOT8	19	4	23	906.899
#38	SLC2A4RG	19	6	25	1010.937
#39	NR3C1	19	7	26	897.257
#40	IRX4	19	8	27	1553.031
#41	JUNB	18	9	27	1714.179
#42	NFATC3	18	7	25	877.722
#43	TAF1B	18	9	27	1601.879
#44	HOXA7	18	10	28	1662.146
#45	ZGPAT	18	10	28	1796.942
#46	MAFG	18	10	28	3023.655
#47	FOXM1	18	6	24	555.694
#48	ZNF45	18	5	23	453.006
#49	RUNX3	18	9	27	1553.101
#50	JUN	18	7	25	1342.942
#51	ZNF187	18	6	24	760.07
#52	ZNF238	18	12	30	1774.072
#53	FOSB	18	4	22	658.009
#54	TBX10	18	8	26	2019.395
#55	IRF1	18	6	24	670.984
#56	MSRB2	17	8	25	1745.801
#57	E2F8	17	11	28	1311.865
#58	HDAC1	17	11	28	1105.579
#59	REXO4	17	9	26	1101.534
#60	HNF4G	17	6	23	814.267
#61	FUBP1	17	9	26	1886.306
#62	MEF2C	17	10	27	835.912
#63	MYBL2	17	8	25	1313.57
#64	FOXO1	17	9	26	1301.922
#65	ZNF175	17	5	22	748.099
#66	RXRB	17	5	22	406.081
#67	HOXA3	17	9	26	1389.013
#68	KLF2	17	5	22	606.324
#69	NFYB	16	5	21	691.297
#70	MTF1	16	9	25	1303.681
#71	CITED2	16	10	26	1466.985
#72	FOSL2	16	11	27	1842.68
#73	KLF15	16	10	26	2630.078
#74	PLSCR1	16	8	24	1396.122
#75	MYC	16	15	31	2512.268
#76	TFDP2	16	8	24	1981.793
#77	HOXB7	16	7	23	1373.347
#78	E2F4	16	11	27	1907.498
#79	NR1I2	16	8	24	1551.369
#80	ELK4	16	7	23	520.344
#81	ELF2	15	6	21	591.83
#82	BUD31	15	10	25	1689.05
#83	EVX1	15	5	20	943.128
#84	TFEB	15	10	25	1222.038
#85	TAF12	15	11	26	877.684
#86	YEATS4	15	11	26	1146.41
#87	BLZF1	15	14	29	1078.248
#88	TFAP2B	15	8	23	1978.886
#89	ZNF236	15	5	20	890.853
#90	ZNF217	15	8	23	776.298
#91	LZTS1	15	9	24	1232.938
#92	PHF1	15	8	23	1171.258
#93	NFATC1	15	12	27	2193.458
#94	NR4A2	14	7	21	1110.949
#95	HOXA11	14	7	21	1163.449
#96	ATF3	14	9	23	994.672
#97	HOXD3	14	12	26	1926.45
#98	LEF1	14	10	24	3079.561
#99	FLI1	14	10	24	1019.145
#100	HOXA9	14	11	25	2631.355
#101	BACH1	14	5	19	318.853
#102	FOXK2	14	6	20	1185.291
#103	TSC22D3	14	10	24	1508.657
#104	HEY2	14	10	24	1660.866
#105	ZNF215	14	6	20	645.768
#106	ALS2CR8	14	6	20	1261.055
#107	NR6A1	14	11	25	1477.485
#108	RUNX1T1	14	10	24	1529.012
#109	SIM2	14	14	28	2790.548
#110	REL	14	14	28	1904.636
#111	MSX1	14	8	22	1492.999
#112	HOXA5	14	2	16	315.103
#113	TRPS1	14	10	24	1112.572
#114	SUPT6H	14	9	23	1108.965
#115	HMGA1	14	12	26	929.04
#116	MZF1	14	9	23	1265.14
#117	GABPB1	13	5	18	1008.486
#118	FOXC2	13	5	18	747.881
#119	PPARA	13	8	21	1621.868
#120	SMAD3	13	11	24	1042.336
#121	ATF6	13	15	28	2256.99
#122	NKX3-2	13	8	21	1461.539
#123	PROX1	13	8	21	1187.19
#124	POU6F2	13	8	21	788.671
#125	RORA	13	11	24	1008.625
#126	EGR3	13	4	17	792.252
#127	SOX9	13	11	24	1850.704
#128	ARNT	13	10	23	1090.141
#129	PRDM2	13	12	25	953.505
#130	ZNF323	13	9	22	765.581
#131	LASS6	13	5	18	664.263
#132	ZBTB38	13	11	24	1524.879
#133	ZEB1	13	8	21	1344.925
#134	ZFPM2	13	10	23	1873.016
#135	FOXL2	13	14	27	2705.391
#136	NPAT	13	11	24	885.747
#137	ZNF193	13	8	21	901.897
#138	HINFP	13	12	25	1024.85
#139	STAT3	13	10	23	1612.097
#140	TAF5	13	13	26	1018.372
#141	EPAS1	13	15	28	1155.679
#142	NEUROD1	13	11	24	1399.949
#143	STAT1	13	12	25	1679.029
#144	IRF7	13	7	20	809.964
#145	USF2	13	8	21	858.843
#146	ETS2	13	14	27	2227.235
#147	TSC22D2	13	9	22	1488.695
#148	IRX5	13	8	21	1282.363
#149	HIF1A	13	7	20	779.954
#150	HMG20B	13	12	25	1876.639
#151	ALX3	13	6	19	1691.503
#152	HOXB2	12	9	21	1073.19
#153	ZXDC	12	8	20	615.016
#154	ZIC1	12	11	23	1079.12
#155	ARNTL	12	9	21	1062.936
#156	EGR2	12	12	24	1010.344
#157	ZNF91	12	10	22	1504.379
#158	FOXD2	12	11	23	1788.092
#159	JUND	12	14	26	1098.32
#160	FOS	12	11	23	1262.758
#161	ZNF131	12	12	24	817.165
#162	BACH2	12	8	20	818.677
#163	ETV6	12	15	27	1236.589
#164	ZBTB48	12	6	18	727.49
#165	MYF5	12	14	26	1485.664
#166	ERG	12	12	24	1655.192
#167	NR2E3	12	6	18	1026.889
#168	FOXN3	12	12	24	1006.285
#169	NFIL3	12	10	22	1042.998
#170	SOX4	12	11	23	1548.279
#171	SPDEF	11	11	22	2024.107
#172	KLF4	11	18	29	2336.4
#173	KLF6	11	16	27	1335.019
#174	ZNF83	11	12	23	948.457
#175	TCF4	11	6	17	336.161
#176	TCFL5	11	12	23	697.208
#177	NFIC	11	11	22	1224.797
#178	BCL6	11	11	22	1150.34
#179	CEBPD	11	12	23	1497.123
#180	TFE3	11	8	19	913.868
#181	ZNF643	11	7	18	704.506
#182	IRF8	11	7	18	1343.986
#183	SCRT1	11	9	20	1243.196
#184	MBD1	11	9	20	855.975
#185	SOX2	11	13	24	1471.404
#186	TAL1	11	12	23	1250.19
#187	ZNF75D	11	6	17	306.529
#188	SRF	11	10	21	645.957
#189	PAX5	11	7	18	1122.321
#190	BTG2	11	13	24	915.474
#191	ELF5	11	12	23	1094.753
#192	ISL1	11	10	21	1551.575
#193	OVOL1	11	10	21	1179.109
#194	NFIX	11	11	22	1492.819
#195	MTA2	11	9	20	999.316
#196	NFX1	11	8	19	612.823
#197	TRIM29	11	9	20	1186.909
#198	ETV5	11	11	22	1504.958
#199	FBXW7	11	9	20	1496.098
#200	CTNNB1	11	9	20	878.683
#201	CTBP1	11	7	18	543.854
#202	HOXC13	11	13	24	1240.548
#203	SPIB	11	7	18	1045.068
#204	PAX4	11	8	19	1298.555
#205	ZNF202	11	6	17	784.461
#206	MAF	10	13	23	2408.072
#207	ETV3	10	12	22	1269.65
#208	PGR	10	11	21	1023.158
#209	NR2F1	10	10	20	1142.089
#210	TEAD4	10	11	21	1514.19
#211	TGIF1	10	13	23	1222.173
#212	TFCP2	10	10	20	497.929
#213	NR2E1	10	17	27	1757.277
#214	GAS7	10	11	21	1314.694
#215	TEAD1	10	14	24	1515.827
#216	TFAP4	10	8	18	1306.309
#217	CEBPB	10	11	21	1244.366
#218	ELF1	10	13	23	1389.596
#219	DLX6	10	7	17	621.411
#220	FOXO3	10	11	21	893.879
#221	HMX1	10	11	21	2151.108
#222	TP53	10	9	19	504.036
#223	MYT1L	10	11	21	1185.683
#224	TBX5	10	11	21	1686.855
#225	NKX2-5	10	9	19	882.309
#226	IRF9	10	9	19	588.25
#227	NFKB2	10	9	19	588.082
#228	NR2C1	10	13	23	1030.34
#229	MAFB	10	11	21	971.113
#230	ZSCAN12	10	4	14	383.862
#231	LHX6	10	11	21	1174.843
#232	SNAI2	10	9	19	1477.639
#233	ONECUT2	10	11	21	1153.503
#234	SREBF1	10	10	20	703.338
#235	SOX30	10	13	23	2276.141
#236	ZNF93	10	9	19	1503.382
#237	ESRRA	10	7	17	734.637
#238	POU3F1	10	5	15	655.058
#239	ZNF81	10	10	20	979.738
#240	SIX1	10	9	19	1630.433
#241	ZFHX3	10	15	25	1662.887
#242	CSDA	10	16	26	1242.958
#243	CEBPA	10	19	29	1631.884
#244	ZNF154	10	9	19	1694.621
#245	GSC2	10	11	21	2229.264
#246	BHLHE40	10	19	29	1074.424
#247	NR1H4	10	9	19	893.82
#248	TP63	9	6	15	416.729
#249	KDM5B	9	9	18	722.12
#250	ETV4	9	9	18	997.949
#251	PAX6	9	9	18	1105.828
#252	STRN3	9	11	20	1018.042
#253	MAFK	9	11	20	1126.588
#254	ECSIT	9	12	21	923.052
#255	HOXA2	9	7	16	669.234
#256	RORC	9	11	20	1371.96
#257	NFAT5	9	10	19	603.808
#258	ZNF444	9	9	18	1001.634
#259	PTTG1	9	12	21	593.974
#260	MNX1	9	11	20	1692.712
#261	IKZF1	9	13	22	1033.005
#262	CDKN2A	9	10	19	1059.064
#263	ZNF174	9	12	21	1872.191
#264	HOPX	9	13	22	1041.469
#265	KLF10	9	14	23	1027.986
#266	NR4A3	9	14	23	1874.767
#267	ZSCAN16	9	6	15	573.251
#268	PBX1	9	11	20	1085.103
#269	ATOH1	9	16	25	1554.867
#270	MEOX1	9	7	16	640.778
#271	ZNF80	9	8	17	853.509
#272	FOXJ1	9	14	23	1819.497
#273	ZSCAN18	9	17	26	1675.935
#274	MLXIPL	9	13	22	1215.533
#275	MYCN	9	12	21	1067.191
#276	HMGB2	9	8	17	520.386
#277	MEF2A	9	7	16	592.704
#278	VSX1	9	9	18	622.882
#279	AEBP1	9	14	23	1035.435
#280	NRL	9	9	18	710.431
#281	SP1	9	10	19	1065.895
#282	HLF	9	6	15	957.705
#283	ZNF155	9	12	21	949.735
#284	KLF5	8	9	17	986.639
#285	BATF3	8	10	18	817.276
#286	PLAG1	8	14	22	1148.028
#287	SIX3	8	11	19	979.914
#288	EGR1	8	9	17	631.019
#289	HOXB6	8	11	19	829.294
#290	HOXC8	8	11	19	1142.692
#291	TADA2A	8	13	21	1250.417
#292	SLC26A3	8	9	17	990.645
#293	SCAND2	8	7	15	476.437
#294	C2orf3	8	14	22	1072.745
#295	GATA6	8	11	19	1477.309
#296	HOXB9	8	9	17	1290.188
#297	PAX8	8	6	14	622.317
#298	NPAS2	8	7	15	675.303
#299	SALL1	8	6	14	1081.42
#300	EMX1	8	10	18	751.135
#301	ZNF134	8	9	17	940.949
#302	GATA2	8	9	17	1452.539
#303	GCM1	8	11	19	884.528
#304	ETV7	8	11	19	1183.268
#305	EGR4	8	12	20	1295.697
#306	ARNT2	8	12	20	1312.678
#307	NEUROG1	8	8	16	1005.556
#308	TSC22D1	8	13	21	866.745
#309	SATB2	8	10	18	1126.756
#310	PKNOX2	8	8	16	945.651
#311	HOXB8	8	9	17	1386.934
#312	POU4F1	8	12	20	1253.621
#313	FOXG1	8	7	15	488.72
#314	SOX21	8	9	17	755.34
#315	ZNF167	8	14	22	1321.786
#316	ERF	8	6	14	472.329
#317	ESRRB	8	10	18	926.694
#318	STAT5B	8	7	15	1415.634
#319	ZEB2	8	7	15	397.518
#320	MLL	8	11	19	1625.357
#321	POU2F2	8	10	18	1010.587
#322	TFAP2A	7	8	15	585.021
#323	BNC1	7	11	18	862.108
#324	RARG	7	12	19	916.325
#325	FOXD1	7	16	23	2147.005
#326	ZNF165	7	15	22	989.272
#327	TEAD3	7	13	20	940.621
#328	WNT5A	7	17	24	968.782
#329	SOX5	7	6	13	444.93
#330	TRIM22	7	16	23	1092.231
#331	CREBBP	7	8	15	659.36
#332	CREBZF	7	7	14	600.249
#333	PAX3	7	8	15	1267.343
#334	BRD8	7	12	19	740.028
#335	GATA4	7	9	16	648.718
#336	ST18	7	12	19	809.018
#337	EHF	7	11	18	944.821
#338	FOXP3	7	12	19	1024.804
#339	HESX1	7	11	18	559.101
#340	POU5F1B	7	7	14	406.985
#341	RCAN1	7	9	16	1375.887
#342	PHOX2A	7	14	21	1353.317
#343	IRF4	7	13	20	863.051
#344	POU6F1	7	10	17	828.56
#345	LHX5	7	11	18	557.185
#346	HES1	7	14	21	1696.342
#347	SMAD6	7	13	20	680.987
#348	NR2F2	7	15	22	1312.225
#349	MEIS2	7	12	19	757.025
#350	ZFP36L1	7	17	24	1232.294
#351	TBX6	7	13	20	970.524
#352	ZHX3	7	12	19	804.942
#353	VAX2	7	10	17	1171.492
#354	HNF4A	7	9	16	305.853
#355	FOXE1	7	11	18	1655.129
#356	OLIG2	7	14	21	1042.389
#357	CREB3L1	7	8	15	798.687
#358	NKX2-1	7	10	17	1122.723
#359	HEY1	7	11	18	925.721
#360	PITX1	7	8	15	480.206
#361	HIC1	7	11	18	845.701
#362	NR2F6	7	10	17	563.138
#363	PAX7	7	11	18	963.356
#364	ZNF3	7	9	16	1004.737
#365	GBX2	7	7	14	498.836
#366	GATA1	7	9	16	553.216
#367	FOXO4	6	13	19	826.718
#368	PPBPL2	6	11	17	678.363
#369	E2F2	6	12	18	757.688
#370	NR3C2	6	10	16	1073.822
#371	POU3F2	6	5	11	363.268
#372	SOX18	6	13	19	1018.785
#373	FOXD3	6	14	20	1445.772
#374	FOXI1	6	8	14	317.606
#375	POU3F4	6	9	15	489.21
#376	ASCL1	6	12	18	768.219
#377	BARX1	6	14	20	970.036
#378	GTF2I	6	12	18	534.149
#379	MECOM	6	8	14	781.222
#380	HMBOX1	6	9	15	834.542
#381	TFEC	6	11	17	799.062
#382	T	6	13	19	1766.929
#383	ONECUT1	6	8	14	619.171
#384	NR0B1	6	9	15	854.814
#385	TBX2	6	14	20	674.516
#386	FOXB1	6	9	15	647.449
#387	YY1	6	11	17	1004.601
#388	SMAD1	6	14	20	1989.213
#389	IRF5	6	12	18	913.887
#390	ZFP37	6	14	20	732.08
#391	SRY	6	8	14	722.843
#392	C11orf9	6	15	21	1356.265
#393	TCF7L2	6	16	22	1230.909
#394	TBX3	6	9	15	650.136
#395	ALX4	6	11	17	1339.805
#396	PITX2	6	10	16	819.767
#397	PKNOX1	6	12	18	782.127
#398	HOXA1	6	12	18	821.223
#399	VTN	6	13	19	1058.943
#400	KLF12	6	9	15	771.52
#401	NFE2	6	13	19	548.106
#402	RB1	6	11	17	458.994
#403	TEF	6	12	18	1511.147
#404	RXRA	6	19	25	1182.608
#405	TCF21	5	12	17	573.829
#406	HOXD13	5	13	18	831.155
#407	E2F5	5	13	18	375.918
#408	RUNX1	5	12	17	833.578
#409	CUX2	5	11	16	1055.76
#410	POU2F3	5	10	15	662.355
#411	SOX11	5	9	14	780.833
#412	TLX3	5	10	15	710.693
#413	SPI1	5	15	20	1947.389
#414	RARB	5	19	24	1411.954
#415	EN2	5	13	18	785.416
#416	CREM	5	12	17	633.603
#417	TCF15	5	13	18	735.165
#418	TLX2	5	12	17	570.643
#419	STAT6	5	18	23	710.648
#420	PPARG	5	9	14	866.366
#421	VDR	5	12	17	636.557
#422	ARNTL2	5	12	17	850.444
#423	ATF5	5	12	17	634.719
#424	FOSL1	5	12	17	1111.292
#425	PDX1	5	13	18	616.231
#426	HNF1A	5	11	16	670.822
#427	SIM1	5	9	14	436.968
#428	NR5A2	5	9	14	522.107
#429	ZNF287	5	12	17	1025.687
#430	ZSCAN2	5	10	15	672.88
#431	BATF	5	15	20	689.562
#432	WT1	5	15	20	669.542
#433	NFIB	5	11	16	989.646
#434	HOXB3	5	9	14	649.41
#435	ZNF135	5	11	16	942.253
#436	E2F1	5	12	17	759.963
#437	PPARD	5	15	20	1010.892
#438	ELK1	5	11	16	451.454
#439	MSL3	5	13	18	890.127
#440	MEOX2	5	6	11	452.691
#441	TBX19	5	12	17	757.939
#442	POU4F3	5	12	17	880.545
#443	EN1	5	11	16	695.518
#444	ETV2	5	10	15	717.478
#445	ZNF268	4	10	14	699.637
#446	DLX2	4	8	12	427.214
#447	MXD1	4	20	24	791.431
#448	NPAS1	4	14	18	459.728
#449	MLLT10	4	8	12	584.173
#450	ESR1	4	13	17	608.033
#451	TADA3	4	11	15	586.108
#452	RUNX2	4	14	18	606.712
#453	GATA3	4	15	19	1130.647
#454	ZNF446	4	12	16	746.035
#455	NFATC4	4	10	14	384.184
#456	ZNF219	4	12	16	568.993
#457	PTH	4	8	12	362.659
#458	PCGF2	4	10	14	498.731
#459	TCF12	4	12	16	793.442
#460	NR4A1	4	10	14	520.717
#461	SATB1	4	10	14	391.316
#462	DBP	4	13	17	368.509
#463	ESRRG	4	18	22	1173.044
#464	TSHZ2	4	18	22	962.385
#465	MSX2	4	15	19	1032.41
#466	SCML1	4	10	14	468.097
#467	MYF6	4	14	18	390.07
#468	AHR	4	14	18	730.124
#469	TWIST1	4	7	11	292.073
#470	CREB5	3	13	16	428.43
#471	HIF3A	3	8	11	254.285
#472	RARA	3	13	16	410.685
#473	SNAPC5	3	15	18	1069.811
#474	HOXB1	3	7	10	440.494
#475	AR	3	12	15	559.502
#476	HOXA4	3	11	14	381.016
#477	HOXD11	3	11	14	630.813
#478	TBX1	3	9	12	590.882
#479	ZNF157	3	17	20	407.947
#480	TAF13	3	12	15	317.372
#481	POU3F3	3	7	10	639.447
#482	DMRT1	3	12	15	898.811
#483	THRA	3	13	16	453.246
#484	NR5A1	3	15	18	523.713
#485	ZNF639	3	11	14	386.589
#486	MSC	3	11	14	292.999
#487	ZIC3	3	10	13	595.635
#488	TFAP2C	3	17	20	382.162
#489	HOXA10	3	16	19	1004.199
#490	FOXH1	2	12	14	398.147
#491	HOXD1	2	9	11	241.34
#492	POU1F1	2	9	11	196.999
#493	REST	2	13	15	673.183
#494	RERE	2	15	17	321.652
#495	CBFA2T2	2	12	14	409.208
#496	RFXAP	2	14	16	351.264
#497	ESR2	2	14	16	245.653
#498	ZNF41	1	6	7	112.806
#499	ETV1	0	20	20	0
#500	FOXA2	0	13	13	0