Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ELK3	35	1	36	40.901
#2	LASS6	30	6	36	2383.543
#3	RUNX3	29	8	37	3517.029
#4	RB1	29	5	34	1583.814
#5	CREB3L2	29	4	33	1817.403
#6	REL	29	5	34	1986.86
#7	TSHZ1	28	4	32	442.038
#8	KLF3	27	6	33	579.304
#9	PHTF1	26	1	27	63.227
#10	HMGA1	25	8	33	3723.244
#11	ADNP2	25	6	31	493.169
#12	MGA	24	4	28	2080.796
#13	KCNH8	24	13	37	3001.838
#14	SNAI3	23	10	33	2263.407
#15	UHRF1	22	2	24	1782.347
#16	TCF3	22	5	27	714.887
#17	LEF1	22	2	24	905.049
#18	ZNF83	22	6	28	341.551
#19	ZNF207	21	3	24	776.66
#20	JUND	21	5	26	563.681
#21	IKZF1	20	12	32	1451.9
#22	SATB1	20	5	25	340.925
#23	USF1	20	4	24	1178.411
#24	MEF2C	20	8	28	754.266
#25	BHLHE41	20	6	26	1126.143
#26	ZFHX3	19	8	27	725.531
#27	BHLHE40	19	10	29	2735.493
#28	TCEAL1	19	7	26	4180.368
#29	CSDA	19	8	27	1390.213
#30	NR4A2	19	2	21	65.673
#31	EGR2	19	8	27	886.916
#32	TSC22D1	18	3	21	536.938
#33	NKX3-1	18	11	29	2641.084
#34	BCL6	18	8	26	1865.916
#35	BCL3	18	5	23	709.28
#36	HOXC4	18	11	29	3013.919
#37	DDIT3	17	4	21	618.796
#38	TCF4	17	15	32	2193.917
#39	ZNF238	17	7	24	1227.405
#40	HOXB3	17	13	30	4301.679
#41	ENO1	17	10	27	1236.245
#42	ZNF117	17	11	28	2935.234
#43	FOSB	17	4	21	405.606
#44	TP53	17	5	22	445.302
#45	PTTG1	16	3	19	82.966
#46	EBF1	16	7	23	1066.701
#47	SMAD5	16	7	23	527.187
#48	JUNB	16	3	19	2667.261
#49	SIX5	16	10	26	2351.689
#50	CNOT7	16	7	23	960.801
#51	EGR1	16	4	20	172.309
#52	MYC	16	12	28	1377.433
#53	CSRNP1	16	2	18	136.693
#54	NR3C2	16	12	28	2144.925
#55	TEAD3	16	5	21	1812.653
#56	KLF10	16	6	22	501.077
#57	E2F7	16	11	27	2355.368
#58	ATF5	16	11	27	1721.253
#59	SREBF2	16	7	23	1874.875
#60	ATF2	15	12	27	1664.322
#61	HOXA3	15	6	21	1647.99
#62	HOXA2	15	12	27	2896.867
#63	FOXP1	15	12	27	1097.029
#64	TRIM29	15	8	23	1280.687
#65	CTBP1	15	9	24	1001.803
#66	FOS	15	5	20	459.285
#67	NFAT5	15	9	24	2073.695
#68	MAFF	15	10	25	2349.782
#69	RCAN1	14	8	22	775.314
#70	TBX21	14	10	24	730.761
#71	TEAD1	14	9	23	1147.961
#72	HAND2	14	6	20	4031.024
#73	GTF2I	14	4	18	245.37
#74	L3MBTL4	14	7	21	514.457
#75	FOXM1	14	3	17	177.826
#76	BACH2	14	7	21	1979.049
#77	GTF2H2	14	10	24	1074.326
#78	KLF2	14	9	23	688.99
#79	ZNF80	14	10	24	1028.471
#80	MSC	14	8	22	1572.043
#81	ZSCAN18	14	10	24	1030.495
#82	MYBL2	14	5	19	662.326
#83	MSRB2	13	11	24	1159.802
#84	MAF	13	9	22	1267.695
#85	HMBOX1	13	14	27	2914.896
#86	NFATC3	13	12	25	1080.032
#87	TSHZ3	13	8	21	1021.404
#88	SCML1	13	11	24	3007.085
#89	ARNT2	13	6	19	1818.563
#90	C2orf3	13	10	23	2438.4
#91	SIX3	13	7	20	985.015
#92	IRF5	13	15	28	3414.832
#93	NR4A1	13	8	21	2217.252
#94	FOXP4	13	12	25	1809.376
#95	EPAS1	13	9	22	1394.377
#96	AEBP1	13	11	24	1734.056
#97	ZRANB2	13	9	22	644.066
#98	TRPS1	13	8	21	2067.657
#99	TGIF1	13	11	24	5068.795
#100	DMRT2	13	7	20	1171.542
#101	OTX2	12	6	18	1361.7
#102	TCFL5	12	11	23	1300.854
#103	PBX3	12	8	20	1519.057
#104	SOX30	12	8	20	1688.387
#105	FOXC1	12	8	20	1933.452
#106	TULP4	12	10	22	1083.026
#107	ARNT	12	6	18	1541.266
#108	NANOGNB	12	10	22	1303.878
#109	SPIB	12	11	23	1307.195
#110	NPAS2	12	9	21	2087.981
#111	POU3F2	12	11	23	2052.88
#112	XBP1	12	8	20	807.444
#113	JUN	12	8	20	3341.574
#114	HIF1A	12	7	19	963.447
#115	HEY2	12	7	19	1325.006
#116	KDM5A	12	9	21	1352.863
#117	AFF1	12	13	25	4195.44
#118	EGR3	12	9	21	1071.386
#119	STAT1	12	9	21	798.873
#120	ZNF274	12	7	19	800.236
#121	STAT4	12	14	26	966.026
#122	ZSCAN1	12	7	19	1607.244
#123	FOXA3	11	7	18	1427.485
#124	NFE2	11	8	19	1327.62
#125	CDKN2A	11	10	21	1053.268
#126	MYF6	11	6	17	1294.497
#127	SOX4	11	4	15	810.249
#128	ZFP36L2	11	10	21	367.234
#129	RXRA	11	6	17	219.95
#130	KLF7	11	11	22	845.244
#131	ZNF90	11	9	20	2844.301
#132	HOXA1	11	10	21	948.892
#133	MYCL1	11	9	20	1473.72
#134	HOXC9	11	9	20	1192.768
#135	E2F2	11	10	21	1601.255
#136	ZNF165	11	9	20	512.977
#137	FLI1	11	8	19	1633.703
#138	BTG2	11	13	24	1387.629
#139	TFDP1	11	10	21	744.21
#140	MECOM	11	11	22	1997.896
#141	PRRX1	11	5	16	925.346
#142	NANOG	11	8	19	1391.616
#143	CEBPA	11	9	20	1533.891
#144	ZFP37	11	11	22	1434.153
#145	MEIS1	11	9	20	2016.8
#146	DLX3	11	6	17	1063.712
#147	HOXD3	11	8	19	1148.04
#148	POU1F1	11	11	22	1654.006
#149	ESX1	10	10	20	1979.621
#150	HOXB2	10	16	26	4397.73
#151	NR2F6	10	12	22	588.536
#152	MYCN	10	8	18	1155.269
#153	FOSL2	10	7	17	1201.077
#154	ZNF91	10	15	25	1609.47
#155	GATA3	10	5	15	1086.71
#156	NR5A2	10	10	20	1452.865
#157	ANKRD30A	10	12	22	4880.911
#158	POU2F1	10	10	20	1268.327
#159	NR1D2	10	8	18	1260.543
#160	GATA4	10	12	22	1645.682
#161	SIM2	10	10	20	3509.756
#162	TFE3	10	8	18	607.2
#163	RERE	10	10	20	2136.169
#164	TEF	10	9	19	1598.623
#165	NFIX	10	10	20	1741.367
#166	SCML2	10	10	20	2759.684
#167	HOXB6	10	12	22	2027.63
#168	LHX4	10	7	17	781.74
#169	C12orf28	10	7	17	973.363
#170	DLX1	10	5	15	1100.362
#171	OTX1	10	9	19	1675.041
#172	LHX2	10	9	19	2420.667
#173	TGIF2LY	10	10	20	1732.738
#174	FOXO6	10	9	19	1336.169
#175	SP1	10	11	21	918.785
#176	FOSL1	10	9	19	1861.107
#177	TSC22D3	9	11	20	953.581
#178	POU4F2	9	7	16	1440.423
#179	BCL11B	9	10	19	1018.654
#180	NEUROD1	9	5	14	1101.141
#181	PPBPL2	9	8	17	1601.28
#182	KLF5	9	8	17	1222.541
#183	MTA2	9	8	17	900.873
#184	ARX	9	11	20	1769.4
#185	BRD8	9	6	15	971.474
#186	HES1	9	9	18	1909.322
#187	HAND1	9	9	18	1517.093
#188	HOXA5	9	8	17	1260.523
#189	PROX1	9	9	18	1497.805
#190	ZNF92	9	8	17	503.627
#191	TLX3	9	10	19	2409.277
#192	ZNF192	9	11	20	1050.189
#193	SMAD3	9	9	18	569.767
#194	TFCP2L1	9	8	17	1776.589
#195	REST	9	7	16	701.634
#196	TCF21	9	6	15	937.807
#197	T	9	5	14	868.793
#198	TADA2A	9	9	18	917.557
#199	SREBF1	9	10	19	960.427
#200	CTNNB1	9	8	17	716.237
#201	TSHZ2	9	9	18	691.244
#202	SOX18	9	7	16	1055.699
#203	GSX1	9	8	17	1542.994
#204	IRX3	9	8	17	1992.789
#205	FOXA1	9	10	19	1386.126
#206	OVOL1	9	10	19	2306.797
#207	TFEC	9	9	18	1322.378
#208	FOXF2	9	9	18	1908.543
#209	BATF2	9	12	21	961.257
#210	OLIG2	9	9	18	1692.109
#211	NKX2-1	9	11	20	1624.825
#212	MEOX1	9	8	17	1174.146
#213	HOXA7	9	10	19	1348.237
#214	GATA1	9	8	17	1377.251
#215	E2F8	9	7	16	2203.218
#216	IRX4	9	7	16	727.066
#217	NR2F2	9	7	16	986.189
#218	ETS1	9	6	15	243.843
#219	GCM1	9	12	21	2280.879
#220	AFF4	8	9	17	1873.844
#221	NPAT	8	10	18	1607.516
#222	C11orf9	8	15	23	2764.808
#223	POU3F4	8	10	18	1854.799
#224	NKX6-1	8	12	20	1673.737
#225	PTH	8	10	18	1964.582
#226	SP3	8	7	15	443.27
#227	FOXO1	8	6	14	760.646
#228	SATB2	8	9	17	2199.447
#229	ASCL1	8	12	20	1350.087
#230	IRF6	8	9	17	1823.71
#231	ZFHX4	8	10	18	1494.048
#232	MESP2	8	8	16	823.137
#233	TP63	8	13	21	1721.395
#234	LHX6	8	13	21	1621.324
#235	ZFPM1	8	8	16	1177.287
#236	NFATC4	8	9	17	995.988
#237	HOXA10	8	13	21	1748.01
#238	NR2E3	8	5	13	649.81
#239	SPIC	8	11	19	1650.661
#240	NCOR1	8	12	20	1274.025
#241	SOX2	8	11	19	1879.6
#242	ASCL2	8	11	19	1425.944
#243	ONECUT1	8	6	14	1852.445
#244	ISL2	8	7	15	763.446
#245	MYNN	8	10	18	1138.187
#246	HOXA9	8	9	17	1119.119
#247	MLLT10	8	5	13	420.282
#248	NR6A1	8	12	20	1441.527
#249	TFAP2B	8	12	20	1353.346
#250	HESX1	8	12	20	950.043
#251	ZNF71	8	7	15	980.102
#252	SIN3A	8	10	18	896.651
#253	ONECUT3	8	9	17	1865.455
#254	MYF5	8	9	17	1299.119
#255	ONECUT2	8	10	18	1078.542
#256	CUX2	8	6	14	479.095
#257	THRB	8	13	21	1590.645
#258	SCAND3	8	9	17	832.591
#259	AHR	8	14	22	1710.615
#260	TEAD4	8	8	16	1023.303
#261	PBX4	8	4	12	934.587
#262	PEG3	8	12	20	1153.137
#263	RARG	8	6	14	868.132
#264	CREB5	8	4	12	455.836
#265	IRF1	8	13	21	1475.143
#266	GSX2	8	11	19	2194.169
#267	ZNF135	8	11	19	929.776
#268	FOXR2	7	5	12	781.242
#269	TCF7	7	16	23	691.229
#270	ZSCAN23	7	8	15	1394.041
#271	EN2	7	10	17	1312.077
#272	ZNF93	7	11	18	1594.934
#273	ZNF397	7	10	17	1077.606
#274	ESRRB	7	10	17	1002.039
#275	NFATC2	7	9	16	1038.733
#276	HSF5	7	15	22	966.898
#277	ZNF628	7	6	13	1351.471
#278	SIX2	7	8	15	707.333
#279	POU3F1	7	10	17	1695.613
#280	MXD1	7	17	24	1073.933
#281	THRA	7	16	23	781.072
#282	ISX	7	7	14	1232.469
#283	DLX4	7	12	19	1353.879
#284	HNRNPAB	7	8	15	983.204
#285	POU4F3	7	11	18	1416.783
#286	GATA6	7	13	20	1802.041
#287	TAL1	7	10	17	1149.988
#288	KLF17	7	10	17	2541.876
#289	ZSCAN10	7	7	14	1062.796
#290	TFDP3	7	9	16	934.74
#291	HCFC1	7	10	17	790.076
#292	ESR1	7	10	17	1415.554
#293	TEAD2	7	12	19	766.2
#294	HOXD13	7	10	17	744.168
#295	TCF7L1	7	12	19	1551.668
#296	ELF3	7	8	15	1282.412
#297	FOXP2	7	11	18	1220.422
#298	ZNF3	7	9	16	1165.202
#299	POU5F2	7	10	17	683.391
#300	ATF6B	7	7	14	634.286
#301	FOXE1	7	9	16	1902.01
#302	DLX2	7	13	20	3391.776
#303	SOX11	7	10	17	959.498
#304	SIX4	7	7	14	1518.034
#305	ZNF215	7	13	20	1657.863
#306	HNF4G	7	7	14	932.475
#307	KLF4	7	8	15	231.845
#308	LHX1	7	12	19	1492.367
#309	HOPX	7	9	16	679.521
#310	NFATC1	7	7	14	1292.693
#311	CREM	7	9	16	1174.962
#312	RARA	7	15	22	1397.721
#313	PGR	7	10	17	1051.74
#314	EHF	7	9	16	831.762
#315	LASS5	7	11	18	1476.422
#316	PAX5	7	11	18	1022.786
#317	MKX	7	11	18	785.875
#318	RELA	6	9	15	1407.709
#319	RARB	6	8	14	714.577
#320	PHOX2A	6	10	16	1191.371
#321	SALL2	6	11	17	665.078
#322	SMAD1	6	6	12	393.425
#323	KLF6	6	6	12	184.44
#324	PDX1	6	9	15	853.097
#325	SRF	6	7	13	884.493
#326	PAX3	6	10	16	1663.758
#327	SLC26A3	6	7	13	559.765
#328	MAFB	6	10	16	948.104
#329	HLF	6	10	16	817.536
#330	PBX1	6	10	16	1255.026
#331	TFAP2C	6	11	17	1974.471
#332	NR1I3	6	10	16	778.52
#333	ZNF643	6	8	14	748.409
#334	FOXO3	6	7	13	1220.441
#335	MEOX2	6	7	13	774.81
#336	KLF1	6	10	16	1359.339
#337	KLF9	6	11	17	1375.289
#338	POU3F3	6	9	15	956.27
#339	DLX6	6	12	18	1939.441
#340	PITX2	6	8	14	964.372
#341	LMX1A	6	8	14	1091.563
#342	LZTS1	6	10	16	1048.127
#343	ZFP36L1	6	9	15	1044.868
#344	SOX9	6	9	15	887.965
#345	NFYA	6	8	14	422.755
#346	ERG	6	10	16	897.325
#347	SALL1	6	9	15	1072.535
#348	SIM1	6	9	15	939.215
#349	FOXF1	6	6	12	494.461
#350	SOX5	6	15	21	2037.669
#351	TBR1	6	8	14	1161.129
#352	HDX	6	12	18	747.158
#353	RUNX2	6	10	16	1479.254
#354	PAX4	6	10	16	1266.323
#355	SLC2A4RG	6	12	18	855.297
#356	NR2E1	6	8	14	1148.038
#357	DMRT1	6	10	16	906.076
#358	PAX6	6	9	15	922.292
#359	TBX3	6	8	14	799.393
#360	MITF	6	9	15	734.258
#361	VTN	6	11	17	1399.279
#362	ETV2	6	12	18	1050.624
#363	RORC	6	9	15	1056.561
#364	SOX17	6	14	20	1086.997
#365	ETV5	6	13	19	677.182
#366	ETS2	6	11	17	967.481
#367	GLI2	6	8	14	624.133
#368	CREBZF	6	13	19	768.04
#369	HR	6	7	13	833.596
#370	TWIST1	6	7	13	769.233
#371	MYT1L	6	7	13	1170.667
#372	SOX1	6	11	17	923.694
#373	PRDM2	6	9	15	274.554
#374	NR4A3	6	13	19	647.453
#375	BLZF1	6	10	16	1085.591
#376	TCF20	5	8	13	518.266
#377	FOXL1	5	9	14	843.923
#378	ZIC5	5	8	13	755.362
#379	TP73	5	11	16	1165.768
#380	ELF5	5	14	19	1165.92
#381	HOXB8	5	9	14	1207.038
#382	ZSCAN4	5	8	13	820.894
#383	ZNF131	5	7	12	585.616
#384	HOXD1	5	10	15	881.357
#385	VSX1	5	10	15	687.445
#386	KLF11	5	8	13	287.938
#387	FOXH1	5	11	16	732.148
#388	ZNF81	5	15	20	1490.153
#389	PAX7	5	5	10	350.833
#390	FOXN4	5	6	11	872.714
#391	GTF2IRD1	5	9	14	313.058
#392	HOXD9	5	7	12	507.536
#393	MESP1	5	11	16	891.384
#394	SMAD4	5	13	18	1239.705
#395	FOXP3	5	8	13	562.524
#396	POU4F1	5	10	15	773.062
#397	MIXL1	5	14	19	1090.822
#398	SOLH	5	8	13	861.891
#399	NR0B1	5	9	14	503.633
#400	NEUROD2	5	10	15	960.215
#401	PHOX2B	5	11	16	1420.531
#402	ZFHX2	5	9	14	537.105
#403	TBX5	5	7	12	563.108
#404	PPARD	5	9	14	726.715
#405	DMBX1	5	13	18	1173.815
#406	ARNTL2	5	8	13	927.703
#407	NR1H4	5	13	18	1595.566
#408	ISL1	5	9	14	608.074
#409	HMGA2	5	9	14	1491.807
#410	ZNF85	5	8	13	929.884
#411	ZIC2	5	7	12	840.073
#412	FOXD1	5	7	12	415.697
#413	GAS7	5	9	14	971.17
#414	NFIB	5	11	16	870.525
#415	NFIA	5	9	14	668.712
#416	RORB	5	9	14	709.093
#417	LHX9	5	12	17	1330.842
#418	ZNF396	5	8	13	1764.912
#419	MMP14	5	4	9	280.413
#420	RUNX1T1	5	11	16	801.634
#421	GSC2	4	10	14	1985.334
#422	NR2F1	4	9	13	671.419
#423	CREB3L3	4	10	14	650.561
#424	ETV7	4	10	14	668.469
#425	ST18	4	10	14	846.773
#426	SNAI2	4	16	20	1398.875
#427	TBX22	4	10	14	798.502
#428	PAX8	4	8	12	665.009
#429	RORA	4	11	15	788.311
#430	ZSCAN12	4	10	14	486.092
#431	PRDM1	4	10	14	1098.973
#432	ZSCAN20	4	10	14	678.516
#433	NKX3-2	4	10	14	1241.093
#434	PPARG	4	4	8	281.979
#435	SMAD6	4	8	12	872.157
#436	NFE2L2	4	9	13	470.732
#437	PBX2	4	9	13	762.507
#438	TBX2	4	12	16	848.33
#439	KLF16	4	8	12	742.388
#440	NR1I2	4	10	14	578.115
#441	ZNF157	4	12	16	975.729
#442	NKX2-3	4	9	13	952.045
#443	PPARA	4	11	15	1025.766
#444	HOXD11	4	8	12	969.491
#445	ATF7	4	11	15	549.983
#446	FOXB1	4	10	14	774.737
#447	TRERF1	4	10	14	777.562
#448	AR	4	5	9	878.408
#449	HOXA4	4	9	13	670.697
#450	FOXC2	4	8	12	809.225
#451	VDR	4	14	18	1163.107
#452	BARX1	4	5	9	257.993
#453	WNT5A	4	7	11	230.426
#454	GATAD2A	4	12	16	710.135
#455	SRY	4	8	12	1770.929
#456	EVX1	4	9	13	892.048
#457	RUNX1	4	10	14	820.104
#458	ESRRG	4	9	13	635.149
#459	HOXB7	4	11	15	651.217
#460	ZFPM2	4	9	13	1018.797
#461	HIF3A	3	9	12	710.37
#462	CSRNP3	3	11	14	743.226
#463	HNF4A	3	7	10	344.49
#464	ETV1	3	7	10	280.219
#465	MSX1	3	8	11	314.515
#466	EGR4	3	5	8	722.292
#467	TBX15	3	9	12	450.661
#468	SOX13	3	12	15	1146.952
#469	TWIST2	3	9	12	627.737
#470	TBX20	3	8	11	187.191
#471	PKNOX2	3	11	14	356.211
#472	MEIS3	3	5	8	370.218
#473	HOXC5	3	9	12	937.163
#474	NFKB2	3	9	12	547.401
#475	BATF3	3	9	12	168.838
#476	MLL	3	11	14	258.596
#477	LHX8	3	12	15	561.623
#478	ZIC1	3	15	18	848.892
#479	HOXD4	3	11	14	386.267
#480	BNC1	3	11	14	811.854
#481	IRF4	3	13	16	694.357
#482	ZFP42	3	12	15	916.581
#483	MSX2	3	9	12	464.507
#484	HOXC11	3	10	13	726.581
#485	ESR2	3	7	10	410.565
#486	TCF25	2	11	13	220.593
#487	FOXD3	2	10	12	485.994
#488	POU2F3	2	8	10	334.296
#489	EMX1	2	11	13	632.45
#490	SOX6	2	12	14	407.419
#491	MYT1	2	11	13	630.26
#492	ZIC3	2	11	13	921.79
#493	SMAD9	2	13	15	561.131
#494	KLF12	2	11	13	2429.792
#495	PLSCR1	2	15	17	618.419
#496	EN1	2	7	9	560.989
#497	TCF7L2	2	11	13	1016.285
#498	TBX1	1	5	6	323.979
#499	CEBPD	1	13	14	226.569
#500	FOXL2	0	10	10	0