Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ARX	65	3	68	165.696
#2	TCF4	59	18	77	12005.763
#3	PA2G4	58	4	62	2421.04
#4	TRIM28	57	3	60	2327.168
#5	PPARA	56	5	61	619.682
#6	RORA	55	8	63	5524.675
#7	ZNF202	51	7	58	1653.498
#8	TFDP1	50	3	53	1664.129
#9	ATOH1	49	7	56	716.345
#10	ETS2	46	7	53	2773.485
#11	ELK4	45	5	50	1741.645
#12	STAT3	44	6	50	2211.322
#13	CITED2	44	9	53	1121.136
#14	TP53	43	5	48	301.238
#15	DRAP1	41	9	50	5684.661
#16	TWIST2	40	4	44	1037.142
#17	ENO1	40	3	43	783.218
#18	NR5A2	39	3	42	264.637
#19	CBFB	39	5	44	604.599
#20	RORC	38	4	42	208.416
#21	GATAD2B	38	9	47	1431.922
#22	HES5	37	10	47	1643.037
#23	EDF1	37	10	47	4100.413
#24	TSC22D3	37	9	46	1748.814
#25	ELK1	35	3	38	152.232
#26	GTF2I	35	5	40	238.591
#27	SP1	34	5	39	392.238
#28	TEAD4	34	5	39	404.521
#29	NR3C2	34	11	45	2871.923
#30	TFDP2	34	12	46	1140.948
#31	SMAD2	33	5	38	683.705
#32	GABPA	33	8	41	1058.078
#33	IRF6	33	6	39	358.324
#34	ZNF445	33	8	41	2139.385
#35	TCF7L2	33	10	43	3489.461
#36	HMGB1	32	9	41	3428.211
#37	VDR	32	7	39	1521.861
#38	FOXQ1	32	10	42	23373.128
#39	NFIC	31	12	43	1089.642
#40	ZXDA	31	15	46	3235.964
#41	PPARD	31	10	41	851.828
#42	NPAS2	31	9	40	1696.821
#43	NR2F6	31	6	37	334.173
#44	TADA3	30	5	35	897.157
#45	TSHZ2	30	6	36	464.612
#46	MECOM	30	11	41	603.712
#47	TRIM29	30	9	39	1363.734
#48	HOXD1	30	11	41	6620.275
#49	IKZF4	30	9	39	614.943
#50	ZNF238	30	6	36	1220.538
#51	SOX6	30	8	38	591.041
#52	KLF6	30	7	37	1791.73
#53	HHEX	29	11	40	1241.604
#54	ZNF394	29	10	39	505.205
#55	SOX17	29	10	39	649.153
#56	FOXO1	28	15	43	5685.191
#57	NFE2L3	28	6	34	1865.311
#58	ZHX1	28	14	42	3710.948
#59	BHLHE40	28	15	43	2071.879
#60	CREM	28	13	41	775.258
#61	PITX1	27	8	35	252.097
#62	ZNF219	27	9	36	683.134
#63	THRB	27	9	36	2691.701
#64	ATF3	27	11	38	1435.33
#65	POU2F2	26	10	36	403.535
#66	RERE	26	8	34	938.694
#67	ATF7	25	17	42	4128.238
#68	ARNTL2	25	16	41	2626.456
#69	TCF7L1	25	13	38	2327.602
#70	TAF13	25	12	37	1538.119
#71	GTF2IRD1	25	5	30	438.198
#72	RELA	24	4	28	157.471
#73	SP3	24	14	38	1289.209
#74	ZNF277	24	10	34	955.331
#75	MSRB2	24	12	36	1959.858
#76	ZNF498	24	11	35	838.42
#77	TAF10	24	11	35	1217.079
#78	TSHZ3	24	5	29	458.469
#79	CREB3L2	24	14	38	1387.932
#80	MLLT10	24	11	35	3293.571
#81	SUPT4H1	23	16	39	810.222
#82	IRF3	23	9	32	4763.87
#83	FOXN2	23	13	36	1402.736
#84	NFYB	23	15	38	781.618
#85	FOXP4	23	16	39	2473.151
#86	CSDA	23	11	34	1274.294
#87	ZFP36L2	22	12	34	827.345
#88	ZSCAN18	22	13	35	795.962
#89	CEBPA	22	17	39	890.259
#90	NFYA	22	11	33	3412.421
#91	CREB1	22	11	33	903.275
#92	ZNF281	22	12	34	1020.835
#93	CSRNP3	22	12	34	3328.661
#94	HMG20B	21	13	34	813.299
#95	TRPS1	21	6	27	748.476
#96	KLF12	21	14	35	1058.854
#97	SREBF2	21	11	32	778.94
#98	JUND	21	6	27	306.241
#99	ARNTL	21	13	34	2957.75
#100	ZBTB25	21	12	33	928.166
#101	FOXK2	21	11	32	1739.331
#102	PROX1	21	7	28	6347.109
#103	ZNF256	21	13	34	425.696
#104	HMGA1	21	11	32	1251.121
#105	EHF	20	12	32	1336.663
#106	MAFB	20	12	32	1093.986
#107	NEUROD1	20	7	27	1931.709
#108	ATF1	20	10	30	405.307
#109	FOXO3	20	15	35	833.165
#110	HOXB7	20	15	35	1301.933
#111	ZEB1	20	9	29	797.416
#112	ZNF148	20	12	32	1513.249
#113	EPAS1	20	7	27	505.101
#114	ZEB2	20	6	26	482.199
#115	AHR	20	17	37	1380.235
#116	STAT5B	20	7	27	133.572
#117	TFCP2	20	19	39	1763.392
#118	NR3C1	20	12	32	1395.379
#119	RCOR1	20	11	31	524.247
#120	ETV5	20	18	38	1395.568
#121	ZKSCAN1	19	16	35	1054.888
#122	SMAD4	19	10	29	2937.999
#123	NR1I2	19	12	31	2528.366
#124	ZNF71	19	10	29	1363.977
#125	NFYC	19	12	31	3981.135
#126	SOX13	19	12	31	768.394
#127	TCF25	19	14	33	1143.435
#128	PHTF1	19	13	32	278.256
#129	RFXANK	19	14	33	638.576
#130	SNAI2	18	8	26	1230.392
#131	E2F5	18	10	28	9570.047
#132	ZNF75D	18	10	28	2776.294
#133	HCLS1	18	6	24	778.925
#134	STAT6	18	14	32	720.924
#135	ATF5	18	10	28	1737.877
#136	YBX1	18	10	28	10098.009
#137	MAX	18	8	26	1186.059
#138	ZNF500	18	15	33	817.138
#139	GTF2H2	18	15	33	5003.329
#140	TAF1B	18	16	34	576.907
#141	AEBP1	18	12	30	483.945
#142	JDP2	18	8	26	1181.284
#143	CEBPB	18	17	35	5660.796
#144	MYC	18	8	26	252.601
#145	HOXA6	17	14	31	815.647
#146	FLI1	17	12	29	906.988
#147	HOXD9	17	8	25	15716.103
#148	NFX1	17	13	30	3009.547
#149	ASCL2	17	11	28	738.988
#150	ISX	17	14	31	1946.232
#151	ZFPM1	17	12	29	2032.851
#152	NFKB2	17	11	28	1503.048
#153	NCOR1	17	8	25	772.381
#154	E2F6	17	13	30	5415.847
#155	JUN	17	13	30	776.902
#156	CEBPD	16	17	33	1631.243
#157	HIC1	16	17	33	1003.4
#158	SOX1	16	13	29	2214.812
#159	HNF4A	16	14	30	676.558
#160	HOXB9	16	14	30	916.026
#161	HAND1	16	6	22	462.148
#162	IRF5	16	11	27	881.633
#163	SLC26A3	15	15	30	21187.638
#164	NOLC1	15	15	30	1759.056
#165	HR	15	11	26	630.152
#166	TCF21	15	13	28	4880.295
#167	RB1	15	16	31	19395.492
#168	ZNF85	15	13	28	541.798
#169	MEIS1	15	11	26	1151.149
#170	NFIB	15	14	29	1022.223
#171	RARB	15	14	29	1860.316
#172	AHCTF1	15	14	29	4270.414
#173	FEV	15	10	25	434.397
#174	HNF4G	15	8	23	505.788
#175	LASS6	15	15	30	466.25
#176	PKNOX1	14	18	32	3249.788
#177	ZNF396	14	15	29	277.626
#178	NFIX	14	14	28	1094.85
#179	BATF	14	15	29	2171.147
#180	TFEC	14	16	30	679.344
#181	ARNT	14	14	28	404.646
#182	CTNNB1	14	13	27	958.704
#183	NFE2L1	14	15	29	712.407
#184	SPI1	14	8	22	391.629
#185	SPIB	14	9	23	20735.562
#186	TSHZ1	14	15	29	3218.675
#187	TRIM25	14	11	25	331.69
#188	IRF9	14	12	26	1454.032
#189	FOXN3	14	11	25	557.486
#190	E2F7	14	11	25	1010.636
#191	IKZF1	14	14	28	744.022
#192	FOXD2	14	15	29	544.641
#193	HOXA10	14	12	26	916.336
#194	MYBL2	13	13	26	2165.99
#195	ZNF367	13	14	27	561.45
#196	CBL	13	15	28	1589.801
#197	BTG2	13	17	30	1016.714
#198	MNT	13	14	27	199.002
#199	THRA	13	16	29	1961.392
#200	MEF2C	13	9	22	697.189
#201	NR4A2	13	11	24	868.959
#202	PBX2	13	14	27	166.316
#203	HOXC4	13	10	23	335.722
#204	RUNX1T1	13	3	16	115.406
#205	ZNF33A	13	17	30	438.676
#206	TEAD2	13	14	27	193.106
#207	RCAN1	13	13	26	425.313
#208	HOXC8	13	10	23	1149.452
#209	MEIS2	13	11	24	554.344
#210	SMAD3	13	11	24	911.533
#211	CNOT8	13	15	28	3899.644
#212	FOXF1	13	7	20	1287.13
#213	NR1H3	12	13	25	1376.878
#214	MAFG	12	17	29	3141.425
#215	SIX1	12	10	22	1604.835
#216	TCFL5	12	10	22	308.018
#217	KLF2	12	17	29	1653.341
#218	PRRX1	12	11	23	1892.735
#219	NANOGNB	12	18	30	1009.984
#220	ZSCAN5A	12	9	21	4981.351
#221	SPDEF	12	17	29	600.624
#222	ZRANB2	12	12	24	640.716
#223	SOX2	12	12	24	2194.606
#224	RORB	12	16	28	606.661
#225	TEAD1	12	12	24	2967.912
#226	ETV4	12	16	28	63629.146
#227	MITF	12	8	20	1166.101
#228	CREBBP	12	10	22	2472.798
#229	FOXG1	11	10	21	16046.763
#230	NR2F1	11	10	21	537.437
#231	KDM5A	11	15	26	2432.858
#232	RARG	11	11	22	884.175
#233	HOXD13	11	10	21	154.61
#234	SCAND1	11	13	24	543.823
#235	ARID4A	11	9	20	218.301
#236	KLF4	11	20	31	2619.031
#237	ZNF41	11	14	25	468.283
#238	TSC22D4	11	22	33	1272.218
#239	HOXB2	11	13	24	1653.763
#240	NKX3-1	11	17	28	1204.912
#241	ZNF274	11	15	26	246.847
#242	FOXP1	11	15	26	708.356
#243	RFXAP	11	17	28	1287.189
#244	LCOR	11	13	24	1261.654
#245	ZFP36L1	11	20	31	668.089
#246	BCL3	11	12	23	455.955
#247	ATF6B	11	14	25	1323.856
#248	PURB	11	9	20	226.953
#249	ZNF207	11	10	21	881.091
#250	SUPT6H	11	17	28	2744.91
#251	IRX2	10	21	31	63154.291
#252	GATA6	10	15	25	1284.303
#253	EGR2	10	16	26	18419.623
#254	TGIF2	10	14	24	994.447
#255	SOX9	10	11	21	5423.725
#256	ZBTB17	10	12	22	812.788
#257	HOXB6	10	12	22	27106.037
#258	ZNF3	10	18	28	443.142
#259	SOLH	10	18	28	972.859
#260	RUNX1	10	17	27	2695.042
#261	CUX1	10	20	30	2356.954
#262	HLF	10	19	29	570.134
#263	EBF1	10	9	19	779.202
#264	HOXA9	10	13	23	3884.327
#265	LASS5	10	13	23	181.211
#266	HCFC1	10	10	20	9397.382
#267	ZNF131	10	12	22	1662.572
#268	JUNB	10	15	25	1031.065
#269	ZNF193	9	18	27	1428.706
#270	TAF4	9	8	17	686.37
#271	NFE2L2	9	11	20	251.595
#272	CLOCK	9	10	19	113.685
#273	HOXA2	9	11	20	610.153
#274	PHF1	9	16	25	416.336
#275	ERF	9	14	23	911.409
#276	SIN3A	9	10	19	792.042
#277	SIM2	9	13	22	12031.62
#278	NFATC4	9	17	26	299.973
#279	ZSCAN12	9	14	23	462.091
#280	ZNF155	9	14	23	1490.542
#281	HOXA1	8	11	19	1399.34
#282	SP140	8	12	20	449.899
#283	RCOR2	8	14	22	433.426
#284	FOXA3	8	16	24	3646.036
#285	HOXD8	8	16	24	367.785
#286	BACH2	8	22	30	721.648
#287	TFAP2A	8	16	24	1723.554
#288	ZNF444	8	15	23	872.924
#289	YEATS4	8	13	21	1291.355
#290	MLX	8	14	22	285.665
#291	KLF16	8	14	22	862.251
#292	ERG	8	14	22	449.642
#293	ZNF91	8	16	24	2904.754
#294	MSX2	8	17	25	1734.988
#295	HOXB4	8	19	27	477.077
#296	MTF1	8	16	24	6968.378
#297	FOXD1	8	12	20	12399.802
#298	ZNF81	8	20	28	548.369
#299	TWIST1	8	13	21	2983.9
#300	TCF3	8	13	21	414.512
#301	MXD1	7	12	19	70.096
#302	CREB3L1	7	14	21	1482.632
#303	ATF6	7	20	27	1831.294
#304	C11orf9	7	20	27	20709.525
#305	STAT1	7	18	25	459.474
#306	TBX3	7	14	21	1455.132
#307	AFF4	7	8	15	281.452
#308	LZTS1	7	19	26	504.322
#309	SOX4	7	13	20	782.65
#310	ZNF639	7	21	28	314.742
#311	REL	7	19	26	348.455
#312	YY1	7	17	24	1755.804
#313	TFCP2L1	7	16	23	412.572
#314	ZNF446	7	20	27	1901.886
#315	FOSB	7	10	17	17841.521
#316	NR4A1	7	7	14	83.41
#317	ZNF140	7	14	21	584.822
#318	CREB3	7	17	24	843.435
#319	ZNF45	7	10	17	618.285
#320	ZNF93	7	11	18	513.52
#321	MBD1	7	17	24	312.485
#322	MSL3	7	21	28	416.526
#323	FOXF2	7	13	20	9241.795
#324	ZNF24	7	20	27	1206.592
#325	GAS7	7	11	18	3687.456
#326	EGR3	7	12	19	570.676
#327	ZKSCAN3	7	13	20	536.803
#328	TAF6	6	10	16	341.229
#329	C5orf41	6	15	21	545.03
#330	BCL11B	6	16	22	853.881
#331	ZNF70	6	15	21	317.619
#332	EGR4	6	9	15	308.467
#333	GATAD1	6	13	19	146.535
#334	CSRNP1	6	15	21	3858.01
#335	PGR	6	15	21	372.085
#336	TFAM	6	11	17	719.572
#337	FOXJ1	6	18	24	4626.175
#338	KLF9	6	18	24	1843.968
#339	TEF	6	18	24	287.824
#340	TSC22D1	6	17	23	618.391
#341	LEF1	6	21	27	542.17
#342	CBFA2T2	6	10	16	960.867
#343	ELF3	6	12	18	172.477
#344	CCRN4L	6	16	22	160.632
#345	ELF5	6	10	16	1755.782
#346	FOXA2	6	18	24	421.003
#347	UHRF1	6	9	15	204.226
#348	PLAGL2	6	15	21	617.562
#349	MNX1	6	19	25	521.05
#350	ZNF92	6	13	19	1029.613
#351	PCGF2	6	18	24	276.449
#352	PITX2	6	18	24	397.616
#353	NPAT	5	10	15	1433.708
#354	TFE3	5	11	16	395.082
#355	HOXA13	5	18	23	1904.179
#356	IRX3	5	13	18	471.25
#357	MMP14	5	15	20	770.16
#358	TBX1	5	15	20	526.859
#359	FOSL2	5	15	20	458.243
#360	BHLHE41	5	14	19	743.831
#361	HMGA2	5	13	18	859.656
#362	POU5F1B	5	17	22	495.819
#363	NKX2-3	5	13	18	1082.762
#364	HIRA	5	15	20	382.16
#365	ALS2CR8	5	14	19	225.068
#366	HOXA3	5	12	17	1547.167
#367	MLL	5	21	26	2034.091
#368	TULP4	5	13	18	1540.827
#369	HOXA7	5	10	15	522.741
#370	FOXM1	5	13	18	685.331
#371	ZNF83	5	9	14	149.636
#372	ZNF167	5	15	20	711.814
#373	ZNF117	5	12	17	1261.863
#374	SATB1	5	16	21	2558.707
#375	HOXB3	5	24	29	4218.642
#376	HES6	5	19	24	4391.505
#377	ATF4	5	11	16	824.078
#378	ZNF215	5	14	19	127.177
#379	FUBP1	5	14	19	203.573
#380	RBCK1	5	14	19	5818.54
#381	MAFF	5	14	19	3735.647
#382	E2F3	5	14	19	757.815
#383	CREB3L4	5	7	12	1433.412
#384	ZXDC	5	13	18	712.366
#385	MEOX2	5	16	21	533.912
#386	TCF7	5	16	21	648.993
#387	MEIS3P1	5	22	27	2261.878
#388	GLI3	5	12	17	4347.612
#389	HEY1	5	14	19	1090.065
#390	GLIS2	5	13	18	957.472
#391	PTTG1	4	14	18	92.417
#392	ARID3A	4	14	18	306.163
#393	HEY2	4	16	20	79.425
#394	ZNF236	4	19	23	401.139
#395	SATB2	4	12	16	937.196
#396	RELB	4	13	17	163.197
#397	TAF5	4	16	20	367.719
#398	IRF4	4	21	25	974.7
#399	ARNT2	4	17	21	665.748
#400	ELF2	4	16	20	543.598
#401	ZBTB48	4	12	16	387.919
#402	MAF	4	11	15	135.868
#403	SPEN	4	18	22	867.442
#404	KLF5	4	22	26	1335.274
#405	TCF19	4	7	11	1338.663
#406	NR1H2	4	14	18	210.884
#407	PRDM2	4	14	18	384.827
#408	RFX5	4	10	14	180.755
#409	ZNF174	4	17	21	662.893
#410	MEF2D	4	12	16	897.774
#411	REST	4	26	30	986.417
#412	ZIC2	4	11	15	1393.677
#413	SNAPC5	4	20	24	596.617
#414	MZF1	4	14	18	162.553
#415	SMAD5	4	16	20	761.513
#416	TAF12	4	14	18	173.204
#417	ETV6	4	17	21	344.331
#418	RUNX3	3	24	27	108.794
#419	RXRB	3	21	24	279.496
#420	ZNF197	3	21	24	109.25
#421	HOPX	3	17	20	161.094
#422	MSX1	3	18	21	918.849
#423	RAX2	3	24	27	118.422
#424	HOXA11	3	17	20	267.245
#425	BCL6	3	20	23	444.988
#426	TAF4B	3	20	23	188.698
#427	GTF2H4	3	12	15	322.524
#428	TGIF1	3	11	14	185.167
#429	PBX3	3	16	19	1122.808
#430	ZGPAT	3	8	11	132.381
#431	NFAT5	3	19	22	4145.72
#432	MYCL1	3	17	20	1004.636
#433	HOXB8	3	20	23	3374.704
#434	NR2F2	3	14	17	79.925
#435	ZFHX3	3	13	16	144.03
#436	MESP1	3	15	18	96.697
#437	E2F2	3	15	18	368.752
#438	FOS	3	19	22	8363.005
#439	ISL1	3	16	19	2203.222
#440	PEG3	3	14	17	2385.986
#441	SCML1	3	17	20	303.789
#442	GCFC1	3	16	19	79.597
#443	EGR1	3	14	17	3738.439
#444	CBFA2T3	3	14	17	869.507
#445	ETV1	3	19	22	152.632
#446	POU2F1	3	14	17	897.766
#447	NR1H4	2	19	21	2456.206
#448	TBX10	2	16	18	1143.965
#449	SMAD9	2	14	16	73.455
#450	HOXB13	2	24	26	1424.468
#451	FOSL1	2	17	19	120.634
#452	HMBOX1	2	16	18	799.241
#453	HOXA5	2	18	20	681.633
#454	SALL1	2	13	15	125.057
#455	HOXB5	2	18	20	396.578
#456	TAF5L	2	24	26	111.076
#457	NFATC2	2	17	19	209.498
#458	DLX6	2	20	22	435.165
#459	SNAPC2	2	19	21	143.096
#460	ZKSCAN4	2	18	20	143.881
#461	IRF1	2	15	17	510.425
#462	GATA3	2	14	16	130.869
#463	PBX1	2	23	25	308.471
#464	SOX7	2	10	12	370.813
#465	FOXP2	1	15	16	60.388
#466	L3MBTL4	1	10	11	97.768
#467	ZBTB38	1	15	16	427.495
#468	NR1D2	1	13	14	98.127
#469	ZFPM2	1	14	15	81.375
#470	WNT5A	1	19	20	4168.019
#471	FOXL1	1	11	12	5309.947
#472	LMO4	1	14	15	114.909
#473	HOXD11	1	15	16	93.832
#474	ZNF397	1	18	19	251.803
#475	ZNF37A	1	15	16	114.794
#476	HOXD10	1	19	20	585.553
#477	MGA	1	19	20	1535.758
#478	NFIA	1	19	20	85.747
#479	E2F8	1	13	14	32.963
#480	HDAC2	1	12	13	75.537
#481	KLF11	1	19	20	41.897
#482	NR4A3	1	14	15	2484.521
#483	ZNF268	1	17	18	492.726
#484	RUNX2	1	13	14	658.066
#485	PRDM1	1	16	17	109.537
#486	WT1	1	18	19	541.86
#487	PPARG	0	21	21	0
#488	TCF12	0	13	13	0
#489	KLF7	0	18	18	0
#490	ZNF33B	0	20	20	0
#491	TRIM22	0	16	16	0
#492	FOXA1	0	26	26	0
#493	DMRT2	0	17	17	0
#494	CTBP1	0	21	21	0
#495	GLIS3	0	19	19	0
#496	ESRRG	0	16	16	0
#497	CREBZF	0	13	13	0
#498	SLC30A9	0	23	23	0
#499	ZNF165	0	18	18	0
#500	DBP	0	18	18	0