Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NR3C2	91	2	93	772.997
#2	ETV4	85	3	88	206.687
#3	NFE2L3	77	5	82	3147.7
#4	MSX1	75	7	82	429.173
#5	KLF7	69	8	77	462.888
#6	FOXQ1	64	4	68	38.127
#7	TGIF2	61	4	65	631.347
#8	TEAD4	60	7	67	569.988
#9	SIX1	59	6	65	5519.887
#10	ASCL2	54	8	62	183.115
#11	SPIB	50	9	59	571.687
#12	KLF4	49	4	53	136.278
#13	SLC26A3	46	13	59	1248.896
#14	ZNF213	46	2	48	274.872
#15	MYBL2	45	8	53	165.891
#16	ARID3A	42	10	52	975.961
#17	TFCP2L1	41	12	53	1992.243
#18	ZNF24	41	10	51	1801.402
#19	PITX2	41	10	51	285.01
#20	KLF3	40	5	45	581.922
#21	SOX11	40	8	48	5655.189
#22	TWIST1	39	9	48	1335.496
#23	HMGA1	38	7	45	192.822
#24	SMAD2	37	4	41	661.111
#25	KLF9	37	13	50	632.217
#26	HOXB13	37	10	47	17550.924
#27	SCAND1	36	7	43	263.546
#28	SALL2	36	6	42	592.938
#29	RFXANK	36	12	48	639.769
#30	FOXP1	36	13	49	762.655
#31	MSL3	36	8	44	7957.237
#32	SPDEF	35	10	45	390.138
#33	MAF	34	8	42	1396.917
#34	FOXO1	34	15	49	2256.294
#35	ISL1	33	13	46	955.273
#36	GRHL3	33	20	53	3098.085
#37	PKNOX2	32	10	42	789.791
#38	E2F6	31	11	42	638.01
#39	CBFB	31	9	40	923.832
#40	NR3C1	31	10	41	411.857
#41	CEBPB	31	9	40	1385.988
#42	SP3	30	11	41	2379.909
#43	NCOR1	30	16	46	923.531
#44	CREB5	30	14	44	3784.371
#45	RAX2	30	9	39	3902.395
#46	DRAP1	29	17	46	981.837
#47	TAF10	29	8	37	846.393
#48	MLL	28	10	38	4821.989
#49	MEF2D	28	8	36	1449.893
#50	TRIM28	27	10	37	382.123
#51	CEBPE	27	11	38	1625.973
#52	GSC	27	14	41	1740.451
#53	PROX1	26	15	41	2320.719
#54	SMAD1	26	16	42	5865.092
#55	MAFG	26	19	45	1612.635
#56	TCF15	26	8	34	1088.528
#57	RUNX1T1	26	4	30	797.189
#58	STRN3	26	12	38	4208.849
#59	GABPB1	25	10	35	448.815
#60	HOXD13	25	9	34	521.571
#61	MEF2C	25	6	31	279.672
#62	FOXM1	25	6	31	65.784
#63	FEV	24	9	33	1531.31
#64	HNF1A	24	15	39	1937.595
#65	ZNF91	24	10	34	1563.727
#66	ZNF135	24	8	32	1823.629
#67	FOXF2	24	4	28	1398.311
#68	GLI3	24	6	30	1401.86
#69	MBD1	24	12	36	646.812
#70	CBFA2T3	24	18	42	521.104
#71	ENO1	23	12	35	1173.212
#72	NR5A2	23	10	33	411.346
#73	OTX1	23	19	42	7681.421
#74	ZFP36L1	23	12	35	1429.61
#75	ISX	23	18	41	2122.766
#76	EN2	22	1	23	18.797
#77	ZNF397	22	13	35	3353.876
#78	ATF7	21	10	31	1066.37
#79	CTNNB1	21	7	28	790.931
#80	SIX4	21	12	33	3497.849
#81	TRIM25	21	20	41	1884.936
#82	TRPS1	21	9	30	2447.003
#83	FOXN3	21	11	32	532.152
#84	FOXD2	21	13	34	3166.022
#85	SNAPC4	21	12	33	1342.922
#86	SOX4	21	11	32	365.597
#87	C2orf3	21	8	29	655.037
#88	CSRNP1	21	4	25	536.265
#89	GTF2IRD1	21	9	30	494.954
#90	RUNX1	21	13	34	762.856
#91	SNAPC2	21	15	36	5823.211
#92	GLI2	21	3	24	686.515
#93	ZNF92	20	9	29	2431.666
#94	WNT5A	20	11	31	462.252
#95	AATF	20	10	30	191.217
#96	PTTG1	20	11	31	114.584
#97	FOXC1	20	17	37	871.037
#98	NKX3-2	20	5	25	4084.682
#99	NR2F2	20	8	28	827.484
#100	ZNF117	20	10	30	1636.783
#101	AFF4	20	16	36	1571.729
#102	MYPOP	19	3	22	62.381
#103	NFE2	19	14	33	733.893
#104	FOXN2	19	8	27	875.438
#105	NR1H2	19	8	27	5982.998
#106	TCF3	19	10	29	288.839
#107	AFF1	19	10	29	1765.648
#108	TCFL5	19	16	35	416.054
#109	SIM2	19	18	37	647.758
#110	RCOR2	19	2	21	120.465
#111	TCF25	18	12	30	4499.826
#112	SOX1	18	6	24	154.434
#113	NFE2L1	18	9	27	2657.101
#114	STAT5A	18	13	31	4366.701
#115	FOSL2	18	8	26	1575.861
#116	PITX1	18	17	35	1349.447
#117	FOXF1	18	6	24	844
#118	FOXK2	18	11	29	259.837
#119	ZNF263	17	11	28	1182.908
#120	TSHZ3	17	5	22	379.072
#121	MEIS1	17	7	24	327.505
#122	HOXD1	17	13	30	542.493
#123	MLXIPL	17	14	31	375.857
#124	PFDN1	17	9	26	6178.847
#125	DLX4	17	13	30	849.055
#126	CSRNP3	16	14	30	1096.939
#127	ZGPAT	16	14	30	2581.49
#128	NR4A1	16	3	19	60.217
#129	TRIM29	16	16	32	553.042
#130	AEBP1	16	4	20	243.525
#131	BHLHE41	16	18	34	222.873
#132	HMG20B	16	11	27	2238.425
#133	LZTS1	16	7	23	551.693
#134	HEYL	16	6	22	2124.555
#135	E2F7	16	10	26	459.213
#136	BATF3	16	11	27	871.65
#137	ATOH1	16	7	23	155.352
#138	NKX2-3	16	10	26	4779.315
#139	TFDP1	16	12	28	574.824
#140	TSHZ1	16	15	31	1986.299
#141	TCF7L2	16	11	27	2224.63
#142	PHOX2A	15	6	21	531.134
#143	LCOR	15	17	32	2087.679
#144	NPAS2	15	12	27	198.874
#145	ADNP	15	13	28	3603.86
#146	LEF1	15	13	28	279.95
#147	NKX2-1	15	9	24	20951.866
#148	ZFHX3	15	15	30	3767.129
#149	ZNF444	15	14	29	603.269
#150	FLI1	15	4	19	220.64
#151	ZSCAN18	15	18	33	2085.604
#152	RXRA	15	11	26	2957.496
#153	SMAD9	15	19	34	4591.087
#154	MXD1	15	11	26	615.716
#155	SRF	15	15	30	1791.003
#156	CEBPA	15	4	19	623.587
#157	ZNF643	15	17	32	2230.947
#158	TWIST2	15	9	24	3578.12
#159	CBFA2T2	15	12	27	2435.624
#160	CREB3L4	14	13	27	9478.584
#161	TAF4	14	16	30	3707.253
#162	HMGB1	14	10	24	4720.44
#163	MMP14	14	11	25	3479.083
#164	NEUROG1	14	6	20	17.094
#165	GTF2I	14	14	28	1557.981
#166	PBX1	14	16	30	485.198
#167	BHLHE40	14	14	28	613.785
#168	MYC	14	18	32	1987.917
#169	DDIT3	14	20	34	3068.991
#170	JUNB	14	13	27	7806.952
#171	FOXP4	14	9	23	586.449
#172	POU2F1	14	12	26	857.138
#173	HNF4A	14	18	32	12102.076
#174	CUX1	14	15	29	903.725
#175	TCF4	13	5	18	284.505
#176	TADA3	13	11	24	2153.534
#177	ONECUT2	13	23	36	6517.052
#178	KLF12	13	17	30	2429.84
#179	PURA	13	13	26	1885.262
#180	ZNF281	13	9	22	1918.993
#181	IRX3	13	9	22	2473.482
#182	FOXK1	13	14	27	410.165
#183	TEAD1	13	15	28	2308.212
#184	HES1	13	20	33	3583.391
#185	RFXAP	13	13	26	3904.755
#186	MITF	12	9	21	418.288
#187	NFATC1	12	9	21	574.485
#188	ZSCAN2	12	16	28	427.04
#189	ZFPM1	12	6	18	71.61
#190	HOXA13	12	15	27	4598.087
#191	ZBTB38	12	18	30	656.701
#192	EGR1	12	4	16	1253.893
#193	STAT3	12	11	23	1225.034
#194	AHCTF1	12	9	21	928.209
#195	ZC3H8	12	17	29	4349.792
#196	HOXB6	12	11	23	1457.601
#197	BATF2	12	13	25	767.778
#198	SREBF1	12	14	26	4761.396
#199	ATF3	12	7	19	343.98
#200	E2F3	12	14	26	1278.028
#201	NR2F6	12	14	26	1986.336
#202	TEAD2	12	17	29	3593.955
#203	HOXD10	12	14	26	364.426
#204	ELK1	12	12	24	1015.967
#205	TEF	12	15	27	720.05
#206	MTA1	12	7	19	1325.113
#207	HOXA9	11	12	23	4298.04
#208	RORC	11	11	22	181.602
#209	MECOM	11	19	30	3915.504
#210	NOLC1	11	13	24	613.248
#211	KLF2	11	13	24	561.823
#212	TCF21	11	11	22	2764.978
#213	SOX9	11	10	21	107.505
#214	NEUROD1	11	12	23	1032.567
#215	ZHX1	11	19	30	6339.936
#216	CREBBP	11	15	26	756.825
#217	ERG	11	9	20	486.886
#218	YEATS4	11	16	27	3837.993
#219	HOXD11	11	9	20	278.842
#220	HNRNPK	11	13	24	1520.661
#221	E2F4	11	10	21	820.494
#222	FOSB	11	5	16	1024.398
#223	SOX17	11	6	17	394.279
#224	ZEB2	11	11	22	1242.315
#225	STAT2	11	18	29	1285.366
#226	IKZF1	11	16	27	519.78
#227	TFEC	11	14	25	1428.811
#228	HOXB5	10	8	18	1950.049
#229	FOXE1	10	9	19	100.961
#230	NR4A2	10	8	18	279.12
#231	ZNF71	10	17	27	991.831
#232	PPARA	10	15	25	374.831
#233	GATAD2A	10	17	27	431.524
#234	ZIC5	10	12	22	2243.189
#235	ARNT	10	17	27	1443.119
#236	ELK3	10	7	17	314.718
#237	FOS	10	8	18	623.353
#238	THRA	10	13	23	1251.219
#239	RARG	10	17	27	628.059
#240	C5orf41	10	15	25	702.225
#241	HOXA10	10	9	19	6036.972
#242	NRL	10	15	25	1181.499
#243	MTF1	10	14	24	460.874
#244	CITED2	10	14	24	1643.723
#245	CREB3L1	10	9	19	558.645
#246	MNT	10	13	23	3151.601
#247	POU3F3	10	10	20	59.949
#248	ERF	10	14	24	326.865
#249	UHRF1	10	10	20	203.876
#250	MZF1	10	17	27	1683.805
#251	VAV1	9	13	22	2268.026
#252	MEIS3P1	9	19	28	206.177
#253	NFYA	9	19	28	636.634
#254	NFIA	9	17	26	1031.65
#255	KCNH8	9	17	26	2386.543
#256	HSF2	9	12	21	904.756
#257	FBXW7	9	15	24	1527.93
#258	HOXB4	9	16	25	1610.13
#259	HOXA3	9	4	13	35.445
#260	KLF15	9	21	30	3592.819
#261	HEY1	9	13	22	766.779
#262	ZSCAN10	9	7	16	140.238
#263	PRDM1	9	8	17	820.908
#264	HIC1	9	10	19	2709.337
#265	ZKSCAN1	9	11	20	2314.396
#266	FOSL1	9	12	21	238.928
#267	IRX4	9	7	16	162.692
#268	HOXB8	9	17	26	601.047
#269	NANOG	9	15	24	939.719
#270	MAFA	9	9	18	1813.456
#271	KLF6	9	16	25	2110.024
#272	NFIC	9	12	21	1052.572
#273	XBP1	9	9	18	273.201
#274	MSX2	9	17	26	4056.697
#275	RBPJ	9	10	19	509.332
#276	ZFHX2	9	15	24	2312.48
#277	RBCK1	9	11	20	690.262
#278	MEIS2	9	12	21	518.706
#279	REL	8	14	22	636.017
#280	FOXA1	8	16	24	738.212
#281	TBX10	8	19	27	441.439
#282	HOXA7	8	15	23	1243.623
#283	KLF16	8	10	18	486.429
#284	EVX1	8	10	18	518.41
#285	PRRX2	8	19	27	846.754
#286	EGR3	8	12	20	2323.263
#287	VENTX	8	19	27	2495.899
#288	MAFF	8	10	18	225.284
#289	SCML1	8	17	25	497.58
#290	SNAI2	8	14	22	592.19
#291	HCLS1	8	8	16	439.627
#292	PA2G4	8	15	23	818.377
#293	RUNX2	8	12	20	574.337
#294	CDX2	8	11	19	807.375
#295	RORA	8	10	18	349.559
#296	NFIL3	8	8	16	571.896
#297	BTG2	8	16	24	1772.428
#298	EPAS1	8	14	22	1441.559
#299	CREBL2	8	16	24	1577.701
#300	PHF1	8	15	23	1650.167
#301	NR1I3	8	16	24	1971.934
#302	MYOD1	8	6	14	205.246
#303	ZXDC	8	13	21	2028.914
#304	PBX3	7	13	20	614.03
#305	YBX1	7	15	22	1675.38
#306	PPARD	7	20	27	1988.655
#307	ZIC2	7	12	19	594.426
#308	TBX15	7	20	27	9076.026
#309	BCL11B	7	22	29	1370.007
#310	ZNF85	7	12	19	1911.7
#311	NFATC3	7	16	23	1126.093
#312	TBX21	7	11	18	2283.778
#313	CNBP	7	14	21	571.945
#314	NR2E3	7	13	20	403.112
#315	HNF1B	7	16	23	345.367
#316	CREB3	7	18	25	3601.156
#317	NKX1-2	7	7	14	29.415
#318	CNOT7	7	13	20	813.656
#319	SATB2	7	13	20	277.669
#320	TSC22D1	7	13	20	422.435
#321	PKNOX1	7	10	17	483.447
#322	HMGA2	7	23	30	1528.373
#323	SNAPC5	7	16	23	6555.83
#324	HAND2	7	8	15	534.332
#325	IRF1	7	12	19	843.552
#326	FOXD4	7	16	23	1859.742
#327	BCL3	7	16	23	1775.712
#328	PLAGL2	7	17	24	5642.698
#329	HOXD9	7	11	18	165.82
#330	TCF12	7	14	21	1019.139
#331	HOXA2	7	13	20	183.921
#332	ETV7	7	18	25	232.374
#333	HR	7	18	25	3980.602
#334	IRF4	7	9	16	147.384
#335	SMAD6	7	14	21	818.961
#336	E2F5	7	19	26	573.412
#337	HOXB2	7	19	26	3658.061
#338	DLX3	7	14	21	1074.082
#339	C1orf85	7	16	23	511.686
#340	HMGB2	7	7	14	416.257
#341	ZNF83	7	23	30	1674.271
#342	THRB	7	13	20	779.79
#343	RCAN1	7	12	19	250.1
#344	GATA6	7	16	23	677.889
#345	ELF4	7	16	23	262.929
#346	ARNT2	7	22	29	1607.352
#347	NFIX	7	17	24	741.381
#348	PBX4	7	18	25	550.212
#349	POU5F1	6	18	24	985.956
#350	ZNF219	6	17	23	185.977
#351	ZNF93	6	15	21	3887.622
#352	TULP4	6	14	20	330.363
#353	SATB1	6	21	27	549.69
#354	SUPT4H1	6	20	26	2281.828
#355	FOXP2	6	12	18	247.946
#356	SP140	6	11	17	278.675
#357	HOXB3	6	18	24	812.475
#358	EBF1	6	12	18	350.92
#359	PLAG1	6	21	27	5899.197
#360	ZNF138	6	17	23	1300.249
#361	ZNF134	6	13	19	1825.738
#362	SCRT2	6	10	16	260.39
#363	HOXD8	6	13	19	526.503
#364	TCF20	6	12	18	368.219
#365	BCL6	6	16	22	765.173
#366	CTBP1	6	15	21	2755.199
#367	MTA3	6	25	31	2397.899
#368	MGA	6	13	19	696.642
#369	RFX1	6	11	17	1677.849
#370	TCEAL1	6	19	25	1523.495
#371	ZNF69	6	15	21	2464.876
#372	ARNTL2	6	16	22	1330.084
#373	HES5	6	17	23	217.051
#374	MYCN	6	10	16	86.324
#375	CREBZF	6	18	24	1417.46
#376	L3MBTL4	6	18	24	6082.084
#377	FOXA2	6	20	26	2042.911
#378	ZNF256	6	13	19	575.65
#379	TAF5L	5	9	14	1424.711
#380	ZSCAN29	5	11	16	477.993
#381	CDKN2A	5	17	22	1979.772
#382	CIR1	5	16	21	652.976
#383	HOXA5	5	15	20	1380.995
#384	EGR2	5	9	14	121.457
#385	HIRA	5	18	23	971.113
#386	NKX2-8	5	13	18	1151.233
#387	PAX4	5	15	20	1769.232
#388	TSHZ2	5	13	18	720.707
#389	ZNF207	5	10	15	554.794
#390	DMTF1	5	17	22	550.78
#391	ZNF167	5	20	25	562.129
#392	TAF6	5	17	22	658.705
#393	LHX6	5	14	19	118.859
#394	SLC2A4RG	5	17	22	433.323
#395	MAFB	5	14	19	1016.733
#396	IRF9	5	21	26	1550.521
#397	FOXA3	5	18	23	3663.229
#398	E2F8	5	18	23	662.048
#399	SOX8	5	11	16	668.245
#400	IRF7	5	20	25	2377.397
#401	WT1	5	22	27	327.743
#402	ZNF268	5	10	15	869.728
#403	HES6	5	19	24	333.553
#404	FOXC2	5	11	16	204.819
#405	ELF3	5	16	21	1056.295
#406	ZNF165	4	13	17	503.162
#407	MNX1	4	18	22	1198.772
#408	TCF7L1	4	12	16	301.063
#409	DBP	4	18	22	779.87
#410	HOXA4	4	18	22	512.197
#411	TARDBP	4	16	20	898.987
#412	NFIB	4	18	22	647.984
#413	TGIF1	4	20	24	1222.646
#414	FOXD1	4	17	21	466.473
#415	TMEM229A	4	14	18	1450.468
#416	HOXB9	4	15	19	708.759
#417	SOX10	4	12	16	8210.659
#418	HOXC9	4	12	16	1548.494
#419	KLF5	4	15	19	2637.648
#420	FOXS1	4	14	18	476.392
#421	TSC22D3	4	18	22	825.863
#422	FOXO3	4	16	20	1160.555
#423	NR2F1	4	19	23	234.66
#424	ETS2	4	13	17	614.655
#425	ARX	4	12	16	748.405
#426	TBX1	4	13	17	5155.36
#427	HLF	4	10	14	71.445
#428	C12orf28	4	19	23	1273.41
#429	HIF3A	4	12	16	178.262
#430	JDP2	4	21	25	866.929
#431	KLF11	4	19	23	714.923
#432	BARX1	4	16	20	810.22
#433	TBX2	4	15	19	626.069
#434	MAFK	4	16	20	1159.62
#435	TFAP2C	3	21	24	626.024
#436	SOX2	3	26	29	4233.947
#437	GLIS3	3	16	19	339.714
#438	TLX2	3	9	12	1869.258
#439	PLSCR1	3	12	15	207.323
#440	HSF4	3	16	19	201.632
#441	EMX1	3	15	18	576.328
#442	TBX3	3	23	26	5999.941
#443	NR1D1	3	18	21	607.636
#444	HOPX	3	16	19	473.219
#445	CREM	3	19	22	196.665
#446	POU6F2	3	22	25	1203.516
#447	BATF	3	19	22	74.103
#448	ZIC1	3	6	9	49.141
#449	ZFP36L2	3	23	26	532.619
#450	DMRT2	3	22	25	829.231
#451	STAT1	3	14	17	434.067
#452	MESP1	3	21	24	359.855
#453	CCRN4L	3	20	23	1055.343
#454	C11orf9	3	24	27	982.311
#455	STAT6	3	14	17	1080.292
#456	E2F2	3	17	20	117.002
#457	ELF5	3	19	22	1228.078
#458	ZNF215	2	21	23	222.383
#459	IRF8	2	20	22	395.973
#460	SOLH	2	19	21	134.318
#461	SCAND3	2	24	26	704.54
#462	DMRT1	2	15	17	178.097
#463	USF1	2	16	18	1435.433
#464	ETS1	2	17	19	565.533
#465	JUND	2	17	19	108.343
#466	LMO4	2	15	17	365.67
#467	GRHL2	2	13	15	703.693
#468	RARA	2	25	27	453.833
#469	PAX8	2	15	17	205.029
#470	FOXJ1	2	22	24	1034.258
#471	HMX1	2	15	17	2404.544
#472	NFAT5	2	19	21	259.524
#473	FOXB1	2	10	12	11.817
#474	ZNF133	2	21	23	664.491
#475	RUNX3	2	17	19	1543.76
#476	CREB3L2	2	21	23	759.41
#477	TP63	2	19	21	175.214
#478	NR1H4	2	15	17	5789.249
#479	SOX18	2	7	9	1538.582
#480	POU3F1	2	9	11	618.481
#481	HMBOX1	1	19	20	100.131
#482	TAF13	1	19	20	68.821
#483	IRF5	1	23	24	254.072
#484	EHF	1	16	17	129.872
#485	CREB3L3	1	12	13	29.352
#486	HNRNPAB	1	18	19	46.547
#487	HOXB7	1	17	18	242.002
#488	KLF10	1	18	19	90.228
#489	GBX2	1	16	17	155.157
#490	CEBPD	1	17	18	1441.078
#491	SMAD3	1	14	15	253.931
#492	IRX2	1	18	19	1687.275
#493	BACH2	1	10	11	20.59
#494	NR1I2	1	16	17	4464.94
#495	ZNF277	0	22	22	0
#496	RELB	0	16	16	0
#497	TRIM22	0	19	19	0
#498	HOXC4	0	8	8	0
#499	IRX5	0	25	25	0
#500	NR1D2	0	16	16	0