Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXA1	101	3	104	110.222
#2	GATA3	96	4	100	40.816
#3	FOXC1	93	1	94	13.36
#4	SPDEF	93	5	98	2587.426
#5	AR	90	4	94	2149.207
#6	ESR1	89	6	95	76.905
#7	EN1	73	6	79	61.335
#8	SOX10	72	1	73	654.35
#9	SOX11	71	6	77	286.186
#10	FOXM1	70	12	82	4172.329
#11	EOMES	69	3	72	53.816
#12	PGR	66	7	73	126.085
#13	IRX1	66	3	69	59.053
#14	HLF	65	10	75	899.745
#15	HSF1	63	8	71	365.894
#16	SPIB	63	6	69	748.59
#17	MEOX1	61	10	71	492.832
#18	ZFP36L2	61	0	61	0
#19	NR2E3	58	12	70	267.9
#20	KLF5	58	10	68	1047.877
#21	SOX8	58	9	67	1752.766
#22	NFE2L3	57	6	63	48.48
#23	MYBL2	56	7	63	167.006
#24	HOXA3	56	4	60	92.591
#25	GLI3	55	11	66	1492.5
#26	E2F8	55	7	62	165.926
#27	IRF6	55	12	67	962.698
#28	TRIM29	54	10	64	122.227
#29	TRPS1	54	9	63	910.767
#30	TP63	54	4	58	63.884
#31	LASS6	53	12	65	3887.788
#32	EGR2	51	11	62	632.435
#33	BHLHE41	51	7	58	217.259
#34	HOXB2	50	13	63	344.051
#35	STAT1	49	10	59	573.301
#36	HOXA5	49	4	53	873.302
#37	TFE3	49	4	53	206.143
#38	NR2F6	48	8	56	1009.204
#39	NR2F1	47	14	61	3751.884
#40	BCL3	47	7	54	772.473
#41	PBX1	47	16	63	1455.737
#42	MYCN	47	13	60	734.307
#43	MYT1	46	14	60	437.337
#44	UHRF1	46	4	50	78.154
#45	PBX4	46	11	57	2220.891
#46	ESRRG	45	17	62	1411.725
#47	ARNTL2	45	10	55	5019.335
#48	HOXC9	45	9	54	2190.798
#49	ENO1	45	12	57	938.971
#50	CDKN2A	44	13	57	485.097
#51	ARNT2	44	20	64	540.015
#52	ZNF238	44	24	68	2401.814
#53	HOXA9	44	7	51	127.779
#54	ANKRD30A	44	12	56	546.631
#55	MEIS3	44	19	63	943.165
#56	HOXA7	43	9	52	616.958
#57	SIX2	43	22	65	713.239
#58	HOXB6	43	12	55	2257.419
#59	HMGA1	42	16	58	697.666
#60	CITED1	42	14	56	273.396
#61	TFCP2L1	41	11	52	124.72
#62	POU2F2	41	12	53	430.203
#63	KLF4	40	13	53	1710.275
#64	HOXB3	40	14	54	142.384
#65	IRX2	40	20	60	2366.102
#66	SOX9	40	16	56	420.148
#67	FOSB	39	6	45	134.905
#68	EGR3	39	9	48	1183.19
#69	MMP14	39	13	52	499.228
#70	ONECUT2	39	18	57	281.922
#71	ATF3	39	18	57	1305.969
#72	PPARG	39	19	58	1756.581
#73	CREB3L1	39	14	53	644.538
#74	MNX1	39	12	51	506.481
#75	E2F1	38	11	49	307.21
#76	CEBPD	38	21	59	1099.014
#77	NFIB	38	15	53	281.447
#78	HOXC11	38	5	43	94.043
#79	ZNF174	38	17	55	370.337
#80	HOXC10	37	4	41	141.854
#81	TFAP2C	37	21	58	1042.035
#82	TCF3	36	15	51	370.511
#83	SLC26A3	36	20	56	806.236
#84	PEG3	36	19	55	4215.338
#85	TBX10	36	21	57	549.87
#86	RUNX2	36	10	46	294.957
#87	MLLT10	36	23	59	1386.225
#88	ETV6	36	23	59	911.156
#89	HOXA10	36	9	45	2163.283
#90	NR5A2	36	14	50	5034.134
#91	FOXO3	35	16	51	322.473
#92	RORC	35	16	51	2368.795
#93	STAT2	35	15	50	1557.254
#94	SUPT6H	35	9	44	487.465
#95	EBF1	35	21	56	1357.648
#96	HOXA1	35	18	53	623.421
#97	PROX1	34	22	56	447.939
#98	NANOG	34	20	54	6193.157
#99	NFIX	34	13	47	836.563
#100	FOS	34	8	42	153.991
#101	TFAP2A	34	14	48	405.838
#102	ELF5	34	12	46	110.935
#103	TFAP2B	34	20	54	498.175
#104	PITX2	33	19	52	989.838
#105	GLIS3	33	13	46	184.003
#106	SOX6	33	11	44	2383.021
#107	ZIC2	32	22	54	2205.732
#108	AEBP1	32	12	44	1611.602
#109	ELF3	32	19	51	514.357
#110	DLX2	32	13	45	281.447
#111	PRRX2	31	15	46	1372.069
#112	NR4A1	31	2	33	507.543
#113	TCF7	31	16	47	2092.326
#114	RUNX1T1	31	21	52	509.575
#115	BNC1	31	17	48	1725.756
#116	ZNF483	30	29	59	1468.618
#117	LMO4	30	22	52	1736.583
#118	TLX1	30	30	60	538.931
#119	FOXQ1	30	19	49	286.171
#120	KCNH8	30	18	48	885.326
#121	POU4F1	30	19	49	334.647
#122	ETV7	29	13	42	681.268
#123	GATAD2A	29	26	55	1104.95
#124	HOXC13	29	14	43	1206.215
#125	SPI1	29	17	46	947.701
#126	PAX6	29	17	46	1144.604
#127	ISL2	29	18	47	1109.475
#128	SIM1	29	24	53	726.452
#129	GRHL3	29	25	54	613.204
#130	ZNF444	29	16	45	274.132
#131	BATF2	29	8	37	179.762
#132	NKX3-2	29	10	39	341.689
#133	HOXD11	29	23	52	2028.793
#134	ZNF117	28	21	49	592.849
#135	HOXC5	28	18	46	378.3
#136	ZNF33B	28	17	45	377.373
#137	NFATC4	28	20	48	588.454
#138	LHX2	27	24	51	359.233
#139	NKX3-1	27	15	42	1675.341
#140	MESP1	27	20	47	688.087
#141	ASCL2	27	23	50	703.662
#142	ETV1	27	24	51	914.017
#143	SNAI3	27	20	47	1285.274
#144	PURB	27	19	46	1736.529
#145	HIF3A	27	22	49	586.013
#146	HEY2	27	27	54	1048.53
#147	CSDA	27	17	44	1934.79
#148	TULP4	27	24	51	667.202
#149	NR4A3	26	8	34	791.908
#150	FOXL1	26	17	43	491.019
#151	ZIC1	26	16	42	1281.504
#152	HOXA4	26	11	37	1449.907
#153	EN2	26	28	54	1242.97
#154	ZEB2	26	30	56	961.054
#155	CUX2	26	29	55	856.137
#156	HSF5	25	22	47	1278.449
#157	RAX2	25	22	47	1355.078
#158	L3MBTL4	25	14	39	4471.179
#159	PITX1	25	20	45	553.544
#160	TRERF1	25	20	45	270.693
#161	HOXA11	25	21	46	1310.304
#162	WT1	25	25	50	1181.198
#163	DMRT2	25	22	47	1183.287
#164	HNF4G	25	26	51	1616.242
#165	WNT5A	25	23	48	915.177
#166	POU4F2	25	24	49	1043.34
#167	SIM2	25	27	52	906.675
#168	ZNF135	25	32	57	1343.359
#169	BARX1	25	22	47	1089.341
#170	POU2F3	24	33	57	778.825
#171	KLF15	24	22	46	811.373
#172	DLX4	24	12	36	281.92
#173	HOXD3	24	25	49	923.965
#174	C12orf28	24	20	44	590.882
#175	TEAD1	24	23	47	1054.038
#176	HOXB13	24	26	50	1324.597
#177	ASCL1	24	22	46	758.94
#178	SATB2	24	26	50	1816.697
#179	LHX8	24	28	52	554.201
#180	DLX6	24	17	41	757.479
#181	SMAD3	24	23	47	443.954
#182	FOXD1	24	27	51	593.847
#183	HES1	23	21	44	2973.879
#184	ST18	23	27	50	890.677
#185	SMAD2	23	26	49	1634.573
#186	MZF1	23	13	36	391.621
#187	RARA	23	21	44	741.085
#188	FOXG1	23	20	43	4180.617
#189	ATF6B	23	19	42	476.232
#190	TBX3	23	9	32	246.854
#191	EHF	23	17	40	1363.585
#192	EVX1	22	27	49	1170.581
#193	NPAS2	22	27	49	491.122
#194	RFXAP	22	19	41	656.358
#195	ZNF449	22	23	45	1190.909
#196	NR4A2	22	20	42	323.564
#197	YY1	22	23	45	516.98
#198	RFX3	22	31	53	1103.069
#199	MSX2	22	14	36	164.282
#200	TSHZ2	22	18	40	728.777
#201	TLX3	22	19	41	487.297
#202	HOXD9	22	31	53	1610
#203	HOXA2	22	15	37	334.209
#204	HOXA6	22	32	54	1200.88
#205	IRX4	21	19	40	1089.092
#206	ZBTB17	21	18	39	281.461
#207	GATA5	21	34	55	1125.703
#208	FUBP1	21	25	46	2676.534
#209	MTA2	21	27	48	565.291
#210	POU3F1	21	22	43	1209.053
#211	SIX1	21	13	34	415.677
#212	HES5	21	31	52	968.99
#213	NEUROD2	21	23	44	1052.639
#214	SOLH	21	27	48	1110.724
#215	TFAP2D	21	27	48	1030.911
#216	SP140	21	18	39	806.534
#217	SALL1	21	20	41	1678.682
#218	EMX1	21	26	47	1145.587
#219	TBX1	20	27	47	325.29
#220	HCFC1	20	29	49	1292.409
#221	HES6	20	17	37	385.825
#222	PAX7	20	30	50	1009.17
#223	OVOL1	20	35	55	1493.588
#224	VTN	20	18	38	506.283
#225	HNF1B	20	31	51	1430.859
#226	ISL1	20	20	40	530.926
#227	HOXB1	20	22	42	698.793
#228	SCAND3	20	26	46	1163.707
#229	STRN3	20	29	49	892.971
#230	DLX3	20	27	47	2720.168
#231	KLF12	20	33	53	1224.788
#232	SNAPC5	20	21	41	430.907
#233	RELA	20	27	47	1606.466
#234	TADA2A	20	22	42	642.111
#235	NKX6-1	20	25	45	2283.633
#236	MYF6	20	28	48	1865.133
#237	E2F2	20	15	35	137.377
#238	ZKSCAN3	20	24	44	1017.685
#239	IRF5	20	21	41	589.664
#240	HOXD4	20	23	43	398.319
#241	DMRT1	19	20	39	556.811
#242	PKNOX1	19	23	42	696.904
#243	GSX2	19	28	47	639.958
#244	SMAD4	19	29	48	1120.823
#245	SOX2	19	25	44	1189.674
#246	MAFK	19	23	42	445.11
#247	RORB	19	18	37	742.81
#248	HR	19	31	50	633.553
#249	FOXP3	19	15	34	156.187
#250	ETV5	19	22	41	711.325
#251	NFATC1	19	27	46	498.698
#252	NKX2-5	18	26	44	524.352
#253	PAX4	18	35	53	1577.417
#254	MXD1	18	32	50	1506.783
#255	BRD8	18	32	50	2007.29
#256	TAF13	18	23	41	1875.812
#257	SIN3A	18	24	42	992.966
#258	ONECUT1	18	29	47	768.303
#259	MESP2	18	23	41	767.329
#260	IKZF1	18	23	41	327.617
#261	ELK1	18	27	45	595.557
#262	HOXD10	18	23	41	531.426
#263	LMX1B	18	21	39	435.746
#264	ZNF3	18	21	39	462.692
#265	CRX	18	29	47	1113.16
#266	OTX1	18	22	40	631.121
#267	NKX2-8	18	29	47	1871.825
#268	ZNF639	18	23	41	776.384
#269	ZFHX4	18	30	48	1019.887
#270	HOXC12	18	28	46	1129.836
#271	ESRRB	18	27	45	671.128
#272	VENTX	17	28	45	1045.675
#273	EGR4	17	23	40	767.557
#274	FOXN4	17	22	39	668.425
#275	POU3F4	17	21	38	857.119
#276	FOXD4	17	26	43	985.674
#277	BCL11B	17	28	45	2243.583
#278	SCAND2	17	35	52	894.545
#279	FOXL2	17	35	52	1325.745
#280	NPAS1	17	27	44	491.294
#281	MYF5	17	26	43	1021.523
#282	FOXC2	17	23	40	859.764
#283	OLIG2	17	26	43	794.734
#284	NFYA	17	32	49	833.7
#285	ATF7	17	27	44	818.228
#286	HNRNPAB	17	36	53	1891.841
#287	ZNF397	17	33	50	1102.436
#288	RUNX1	17	22	39	633.595
#289	FOXD3	17	24	41	3066.43
#290	CSRNP3	17	37	54	1580.525
#291	NFE2	17	32	49	907.602
#292	RERE	17	27	44	4442.992
#293	LHX9	17	32	49	1623.617
#294	HIC1	16	25	41	554.962
#295	TLX2	16	27	43	1240.258
#296	NR1I3	16	35	51	1029.516
#297	HOPX	16	27	43	1240.942
#298	THRA	16	32	48	973.601
#299	ZSCAN10	16	26	42	947.525
#300	SOX5	16	30	46	806.741
#301	SREBF1	16	31	47	2439.269
#302	NFIA	16	30	46	1392.893
#303	ZSCAN18	16	29	45	663.451
#304	SPIC	16	31	47	940.374
#305	NKX2-3	16	30	46	1025.535
#306	ZFHX3	16	30	46	595.219
#307	ZNF85	16	29	45	5260.178
#308	SEBOX	16	27	43	952.731
#309	FOXA2	16	25	41	960.747
#310	POU3F2	16	29	45	708.949
#311	HMX1	16	25	41	572.193
#312	CREM	16	31	47	532.481
#313	SOX21	16	25	41	1241.187
#314	ZHX3	16	27	43	1652.798
#315	KLF17	16	30	46	1558.335
#316	NPAT	16	31	47	608.131
#317	HSF4	16	30	46	755.91
#318	NEUROG1	16	36	52	1570.205
#319	ZNF219	15	29	44	659.8
#320	PHOX2B	15	31	46	1092.289
#321	CBL	15	34	49	1237.716
#322	TCF21	15	31	46	1155.488
#323	PPBPL2	15	24	39	410.835
#324	TBX20	15	28	43	1570.779
#325	PKNOX2	15	27	42	457.002
#326	GCM1	15	27	42	2149.585
#327	LEF1	15	29	44	445.042
#328	HMGB2	15	28	43	509.397
#329	FOXA3	15	26	41	920.473
#330	MLXIPL	15	29	44	867.232
#331	ZNF81	15	32	47	734.397
#332	TFAP4	15	32	47	1018.2
#333	ZNF167	15	34	49	1519.204
#334	CREBZF	15	26	41	708.755
#335	SCRT1	15	27	42	844.772
#336	TBX22	15	31	46	842.555
#337	NR0B1	15	41	56	2154.648
#338	ALX4	15	26	41	720.212
#339	MKX	15	33	48	912.243
#340	MAFG	15	21	36	354.024
#341	IKZF3	14	25	39	351.794
#342	ESX1	14	22	36	622.059
#343	FOXH1	14	31	45	670.283
#344	ZNF154	14	31	45	847.518
#345	POU4F3	14	32	46	539.723
#346	C11orf9	14	32	46	1059.046
#347	LMX1A	14	31	45	610.506
#348	CTBP1	14	33	47	1012.42
#349	TSC22D3	14	33	47	830.563
#350	ZSCAN2	14	26	40	645.083
#351	SOX1	14	30	44	755.238
#352	GATA1	14	28	42	598.795
#353	TGIF2LY	14	27	41	782.703
#354	ETV2	14	26	40	520.191
#355	RORA	14	34	48	830.531
#356	KLF1	14	25	39	520.942
#357	NFE2L2	14	28	42	1149.774
#358	PDX1	14	29	43	1460.417
#359	ALX3	14	26	40	317.355
#360	HAND1	14	25	39	788.687
#361	PLSCR1	14	26	40	739.111
#362	HMGA2	14	28	42	761.123
#363	TCF15	14	31	45	609.22
#364	PBX3	14	30	44	936.172
#365	POU6F1	13	30	43	938.039
#366	DLX1	13	25	38	647.331
#367	POU1F1	13	32	45	1348.99
#368	GATA4	13	32	45	1832.423
#369	ETV4	13	33	46	422.959
#370	FOXE1	13	27	40	811.571
#371	TP73	13	32	45	713.743
#372	FOXJ1	13	31	44	796.941
#373	ZIC3	13	25	38	720.435
#374	TFDP3	13	34	47	5053.912
#375	KDM5B	13	28	41	871.973
#376	RARG	13	24	37	659.861
#377	ZNF80	13	26	39	555.839
#378	TBX2	13	31	44	840.175
#379	REST	13	31	44	1012.129
#380	GSX1	13	33	46	831.845
#381	TBR1	13	28	41	811.53
#382	HAND2	13	33	46	1223.184
#383	FOXR2	13	30	43	1166.958
#384	MIXL1	13	33	46	691.89
#385	TAL1	13	27	40	540.962
#386	HNF1A	13	34	47	2144.75
#387	GBX2	13	29	42	583.352
#388	TWIST2	13	32	45	532.255
#389	TBX6	13	28	41	492.891
#390	ETV3	13	27	40	692.906
#391	PAX5	13	27	40	701.064
#392	ZNF90	12	28	40	647.438
#393	MYCL1	12	22	34	317.077
#394	ZNF131	12	29	41	687.413
#395	SMAD6	12	33	45	527.085
#396	BLZF1	12	26	38	555.905
#397	FOXB1	12	34	46	893.71
#398	NR2E1	12	25	37	347.674
#399	SIX4	12	24	36	486.177
#400	ZFP42	12	30	42	1552.678
#401	SOX30	12	30	42	1797.12
#402	NR6A1	12	40	52	797.154
#403	MLL	12	27	39	498.464
#404	SIX5	12	30	42	731.129
#405	ZIC5	12	38	50	978.541
#406	SIX6	12	29	41	897.659
#407	ISX	12	29	41	722.598
#408	MEOX2	12	33	45	578.408
#409	FOXO1	12	33	45	855.553
#410	GATA6	12	30	42	820.018
#411	HOXD13	12	30	42	676.675
#412	HMG20B	12	27	39	327.159
#413	SP3	12	30	42	715.238
#414	ZSCAN23	12	29	41	677.086
#415	HIRA	12	35	47	2441.435
#416	CREB3L3	12	30	42	1171.233
#417	ZNF207	12	28	40	721.32
#418	TADA3	11	28	39	670.259
#419	SLC2A4RG	11	36	47	866.569
#420	TSC22D1	11	35	46	1276.574
#421	VDR	11	31	42	657.971
#422	KLF9	11	30	41	636.774
#423	SP4	11	26	37	1119.216
#424	LZTS1	11	34	45	1158.515
#425	SMAD9	11	23	34	549.745
#426	LHX1	11	28	39	977.857
#427	OTX2	11	36	47	601.968
#428	LASS5	11	29	40	530.197
#429	ZSCAN1	11	29	40	546.834
#430	MITF	11	33	44	593.096
#431	NEUROD1	11	33	44	765.752
#432	POU6F2	11	29	40	583.068
#433	FLI1	11	31	42	787.623
#434	NCOR1	11	31	42	510.728
#435	TEF	11	28	39	515.114
#436	NR1H4	11	27	38	375.332
#437	DMBX1	11	33	44	898.192
#438	NOBOX	11	34	45	984.976
#439	TSC22D2	10	23	33	374.969
#440	MYT1L	10	33	43	842.141
#441	MYNN	10	29	39	460.369
#442	PPARA	10	30	40	603.049
#443	NRL	10	37	47	1062.194
#444	ATF5	10	27	37	524.829
#445	TEAD2	10	35	45	771.94
#446	TBX5	10	36	46	827.583
#447	RCAN1	10	30	40	327.992
#448	C2orf3	10	26	36	534.158
#449	ATOH1	10	29	39	645.678
#450	FOXI1	9	36	45	341.841
#451	PCGF2	9	33	42	542.008
#452	PAX8	9	31	40	413.675
#453	ARNT	9	27	36	365.789
#454	IRF4	9	27	36	345.292
#455	RBPJL	9	29	38	562.027
#456	KLF2	9	33	42	734.347
#457	GLI2	9	33	42	560.637
#458	EPAS1	9	28	37	465.914
#459	ELK4	9	30	39	761.781
#460	GSC2	9	37	46	1016.194
#461	ZSCAN4	9	28	37	423.259
#462	NR5A1	9	27	36	351.089
#463	VSX1	9	33	42	623.618
#464	ZNF71	9	32	41	948.118
#465	POU2F1	9	34	43	644.242
#466	CREBBP	9	34	43	503.354
#467	POU3F3	9	31	40	396.653
#468	ZSCAN12	9	30	39	544.696
#469	PPARD	8	33	41	309.058
#470	NFATC2	8	32	40	1060.188
#471	ZNF287	8	31	39	582.235
#472	JUND	8	34	42	655.181
#473	MECOM	8	32	40	350.508
#474	NKX2-1	8	28	36	542.499
#475	NFKB2	8	28	36	720.155
#476	ESR2	8	32	40	686.649
#477	ARX	8	29	37	547.91
#478	TCF20	8	24	32	635.328
#479	ZNF157	8	32	40	329.059
#480	RARB	8	37	45	422.433
#481	POU5F2	8	26	34	1122.518
#482	PRDM2	7	28	35	501.179
#483	ZNF215	7	30	37	359.277
#484	ZFP36L1	7	28	35	409.627
#485	HOXD1	7	39	46	398.007
#486	FOXD2	7	32	39	399.721
#487	AFF4	7	30	37	455.805
#488	NR1I2	7	33	40	1793.875
#489	PAX3	7	35	42	651.326
#490	SOX15	6	26	32	513.21
#491	FOXP2	6	29	35	338.256
#492	PTH	6	34	40	608.931
#493	HOXB8	6	30	36	544.74
#494	SIX3	6	38	44	455.445
#495	MAF	6	33	39	436.131
#496	SRY	5	38	43	303.065
#497	HNF4A	5	27	32	195.44
#498	HOXA13	5	34	39	231.753
#499	FOXK1	4	28	32	393.179
#500	ZNF396	1	38	39	44.923