Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TEAD2	79	1	80	123.469
#2	PITX3	63	3	66	172.054
#3	MAFG	60	5	65	201.468
#4	CNOT7	57	11	68	1823.015
#5	HEYL	54	11	65	1652.198
#6	SOX15	51	5	56	463.788
#7	PROX1	51	7	58	1158.962
#8	RAX	49	3	52	55.099
#9	CITED2	49	10	59	4492.121
#10	TCF15	48	4	52	64.98
#11	MYBL2	47	8	55	206.873
#12	MYOD1	47	7	54	1353.428
#13	EMX1	46	10	56	2978.431
#14	NKX3-1	45	10	55	635.9
#15	ZSCAN5A	45	5	50	597.027
#16	STAT2	44	11	55	1582.439
#17	MLX	44	11	55	1099.26
#18	POU6F1	44	15	59	1663.685
#19	ATF5	43	11	54	996.099
#20	BARHL1	42	10	52	251.692
#21	PRRX2	42	11	53	3305.259
#22	MYOG	39	13	52	1318.889
#23	ETV4	39	12	51	667.938
#24	POU2F2	38	12	50	1508.055
#25	MNX1	37	12	49	3383.391
#26	KLF16	37	14	51	1155.813
#27	RCOR1	37	10	47	565.654
#28	ZFPM1	36	9	45	917.438
#29	CDX2	35	6	41	135.604
#30	ZNF449	35	14	49	4726.494
#31	HOXC13	34	6	40	175.195
#32	CDKN2A	34	9	43	791.538
#33	FOXP3	34	16	50	615.242
#34	NKX1-1	34	9	43	824.313
#35	PURA	33	13	46	545.127
#36	RXRB	32	4	36	445.328
#37	ZNF277	32	11	43	828.041
#38	ZNF174	32	7	39	877.143
#39	LHX4	32	12	44	1010.829
#40	TP73	32	4	36	338.593
#41	HOXC5	32	9	41	824.268
#42	RB1	31	6	37	1483.154
#43	HMX1	31	8	39	1073.699
#44	MYCN	31	5	36	123.991
#45	HSF4	31	9	40	648.545
#46	FOXL1	31	14	45	591.565
#47	SOX10	31	10	41	947.1
#48	MMP14	30	8	38	285.686
#49	CITED1	30	8	38	415.047
#50	PDX1	30	10	40	234.182
#51	SOLH	30	11	41	347.746
#52	RUNX3	30	14	44	1143.653
#53	VSX1	30	14	44	1042.787
#54	LHX5	29	8	37	341.812
#55	FOSL2	29	6	35	1427.989
#56	LMX1B	29	13	42	795.304
#57	NR4A1	29	13	42	991.857
#58	ZNF238	29	6	35	905.085
#59	HR	29	15	44	1064.303
#60	HMGA1	29	10	39	6921.228
#61	ZSCAN10	29	10	39	383.355
#62	NFATC4	28	11	39	579.086
#63	HNF4A	28	12	40	1503.176
#64	ZNF219	28	17	45	1673.56
#65	NR2E3	28	12	40	4581.077
#66	SOX7	27	11	38	348.932
#67	FOXN3	27	14	41	1916.759
#68	SREBF1	27	11	38	821.003
#69	BUD31	26	10	36	2742.326
#70	HMGB2	26	14	40	420.01
#71	MEIS3	26	14	40	2584.36
#72	NR2F6	25	8	33	959.757
#73	PPARA	25	11	36	741.432
#74	TCF25	25	17	42	779.085
#75	SPEN	25	9	34	320.811
#76	ZNF169	25	12	37	1743.519
#77	SMAD6	25	11	36	2116.848
#78	RUNX1	25	8	33	508.422
#79	ZNF192	25	9	34	476.008
#80	AEBP1	25	14	39	11444.781
#81	MESP1	25	8	33	562.617
#82	TSHZ2	25	12	37	2650.418
#83	HES6	24	18	42	1235.059
#84	TFAP4	24	12	36	2693.355
#85	ZBTB17	24	11	35	324.405
#86	LHX6	24	10	34	950.946
#87	TBX1	23	16	39	2725.881
#88	HSF1	23	9	32	211.941
#89	ALX3	23	13	36	298.381
#90	FUBP1	23	17	40	1993.5
#91	RCOR2	23	6	29	359.732
#92	GBX1	22	10	32	164.678
#93	HOXB3	22	8	30	233.583
#94	KLF2	22	16	38	1788.729
#95	NOTCH1	22	18	40	1052.33
#96	TAF4	22	6	28	652.559
#97	CREB3L1	22	5	27	131.706
#98	IKZF1	21	11	32	285.337
#99	ARNTL2	21	11	32	783.198
#100	ZFP36L2	21	7	28	734.973
#101	ATF7	21	11	32	200.833
#102	NPAS1	21	16	37	1449.044
#103	TRIM25	21	17	38	9579.262
#104	GATAD2A	21	11	32	429.58
#105	EGR4	21	16	37	566.824
#106	HNF1B	21	16	37	1259.112
#107	BACH1	21	11	32	813.245
#108	FOXF1	20	16	36	2322.19
#109	SIX5	20	10	30	1605.287
#110	BCL3	20	11	31	270.493
#111	FEV	20	11	31	231.747
#112	ST18	20	18	38	1162.422
#113	MLLT10	20	13	33	2003.142
#114	HNF4G	19	13	32	2498.436
#115	TFDP3	19	14	33	685.763
#116	CSDA	19	16	35	1118.584
#117	ZFHX3	19	10	29	1956.695
#118	TAL1	19	19	38	932.298
#119	YY1	19	10	29	2203.918
#120	SMAD3	19	4	23	85.129
#121	MESP2	19	10	29	652.443
#122	ARX	19	11	30	1022.968
#123	HOXA5	19	16	35	1594.236
#124	LHX1	19	15	34	263.292
#125	ZNF157	19	10	29	537.371
#126	CRX	19	19	38	340.695
#127	RFX1	19	13	32	2967.634
#128	NR2C1	19	12	31	3194.813
#129	HCFC1	18	18	36	822.781
#130	FOXH1	18	13	31	551.567
#131	NPAS2	18	11	29	1146.202
#132	BARX1	18	15	33	3084.214
#133	ESR1	18	16	34	810.298
#134	CREBZF	18	18	36	2182.375
#135	ZSCAN2	18	13	31	899.081
#136	TADA2A	18	12	30	517.536
#137	MGA	18	10	28	1202.817
#138	PHOX2A	17	17	34	3551.83
#139	VDR	17	17	34	649.412
#140	NFE2	17	13	30	1929.599
#141	HOXA4	17	13	30	364.548
#142	HOXD10	17	14	31	1219.369
#143	GATA1	17	13	30	946.108
#144	POU3F1	17	12	29	327.278
#145	ZNF117	17	10	27	1231.668
#146	TP53	16	11	27	1091.147
#147	TBX10	16	9	25	883.926
#148	HOXD13	16	17	33	1984.095
#149	FOXB1	16	17	33	773.697
#150	EGR2	16	6	22	421.226
#151	CUX2	16	19	35	2928.15
#152	TLX2	15	17	32	2336.009
#153	GABPB1	15	17	32	1173.049
#154	TEF	15	11	26	1457.401
#155	ZNF93	15	14	29	949.217
#156	TRERF1	15	15	30	692.119
#157	SMAD4	15	10	25	278.853
#158	FOXP2	15	10	25	4033.906
#159	MSX1	15	16	31	758.018
#160	NFIB	14	17	31	2720.587
#161	NEUROD1	14	15	29	1168.336
#162	TFAP2C	14	16	30	1665.199
#163	HOXC11	14	13	27	2749.575
#164	PAX5	14	9	23	2237.801
#165	ZNF483	14	11	25	3418.741
#166	TAF13	14	13	27	1829.044
#167	ETV5	14	16	30	1012.385
#168	TBX6	14	13	27	965.666
#169	SEBOX	14	13	27	853.965
#170	ZNF71	14	12	26	523.188
#171	TLX1	14	11	25	1672.65
#172	TADA3	14	16	30	3155.518
#173	C11orf9	14	15	29	6783.905
#174	MEF2D	14	17	31	6750.073
#175	ESX1	14	11	25	308.78
#176	POU4F1	14	13	27	331.175
#177	FOXG1	14	15	29	2006.373
#178	SCRT1	14	12	26	199.487
#179	AHCTF1	14	14	28	1386.149
#180	NR1I2	14	15	29	1913.501
#181	MXD1	14	11	25	1124.045
#182	MIXL1	14	13	27	246.753
#183	TBX3	14	11	25	6386.142
#184	MYNN	13	14	27	509.031
#185	SP3	13	17	30	627.587
#186	SOX1	13	14	27	1666.98
#187	MAF	13	12	25	6425.188
#188	ELF5	13	15	28	1904.307
#189	ZNF175	13	11	24	677.566
#190	EBF1	13	16	29	1191.365
#191	KLF17	13	12	25	1123.281
#192	HOXA6	13	19	32	1862.77
#193	KLF11	13	15	28	595.54
#194	HOXC9	13	15	28	952.712
#195	SUPT6H	13	16	29	637.673
#196	NKX2-8	13	12	25	595.01
#197	SCAND2	13	20	33	2133.512
#198	ETV7	13	17	30	491.934
#199	ZSCAN12	12	17	29	2478.22
#200	RORB	12	14	26	1649.616
#201	NFATC1	12	13	25	1468.186
#202	FOXO1	12	11	23	2056.523
#203	POU3F4	12	13	25	1088.442
#204	MTA2	12	11	23	167.303
#205	ETS1	12	16	28	1788.316
#206	PPARG	12	11	23	847.845
#207	POU2F3	12	17	29	5528.257
#208	HOPX	12	16	28	1128.807
#209	MZF1	12	18	30	3276.939
#210	PAX8	12	11	23	837.804
#211	FOXA2	12	12	24	576.599
#212	E2F2	12	16	28	1346.156
#213	ZKSCAN3	12	13	25	515.212
#214	CTNNB1	12	17	29	2152.057
#215	ZSCAN18	12	17	29	805.365
#216	PKNOX2	12	10	22	2319.974
#217	NKX3-2	12	21	33	4397.611
#218	HAND2	12	18	30	2922.235
#219	MLXIPL	12	12	24	3206.882
#220	MYF6	12	9	21	187.672
#221	GATA4	12	14	26	1368.767
#222	KCNH8	11	18	29	1163.717
#223	GATAD1	11	14	25	1666.919
#224	CREB5	11	16	27	1014.281
#225	NKX2-5	11	13	24	630.001
#226	ATF6B	11	15	26	1030.497
#227	MYCL1	11	15	26	1292.3
#228	ZNF438	11	14	25	2776.587
#229	THRA	11	15	26	691.329
#230	HNF1A	11	20	31	1861.863
#231	EN1	11	18	29	2233.58
#232	ZNF81	11	17	28	1583.242
#233	TFCP2L1	11	20	31	2913.105
#234	IRF5	11	14	25	211.168
#235	OVOL1	11	21	32	1229.349
#236	EVX1	11	16	27	291.885
#237	GATA6	11	11	22	183.997
#238	LZTS1	11	13	24	9084.471
#239	RORA	11	15	26	653.442
#240	HOXD9	11	14	25	1531.807
#241	KDM5B	11	16	27	1891.822
#242	HOXA9	11	16	27	2387.385
#243	TFAP2A	11	12	23	1561.657
#244	VTN	11	12	23	1292.366
#245	JUND	11	13	24	893.046
#246	ZSCAN23	11	11	22	308.927
#247	FOXL2	11	14	25	957.946
#248	KLF15	11	15	26	3065.86
#249	TCF20	11	13	24	917.085
#250	NFIX	11	15	26	1651.666
#251	TBX15	11	17	28	2081.287
#252	HOXD1	11	13	24	620.57
#253	HOXA10	11	12	23	2970.461
#254	AFF4	11	15	26	856.173
#255	ZNF193	11	19	30	1582.76
#256	MKX	11	14	25	1756.651
#257	RUNX2	11	17	28	1533.03
#258	NR1H4	11	12	23	973.527
#259	NCOR1	11	14	25	1619.652
#260	USF1	11	9	20	2160.747
#261	MEF2C	10	16	26	1803.608
#262	MEOX1	10	13	23	1750.829
#263	FOXK1	10	13	23	610.443
#264	REST	10	16	26	1412.533
#265	ZNF215	10	19	29	924.71
#266	NR1I3	10	21	31	2097.622
#267	PRDM1	10	13	23	294.188
#268	ASCL1	10	18	28	1077.492
#269	ERG	10	17	27	3625.43
#270	RXRG	10	18	28	1861.692
#271	SOX17	10	11	21	734.114
#272	OTX2	10	13	23	768.391
#273	FOXO3	10	19	29	1387.015
#274	TRIM29	10	16	26	830.398
#275	SLC26A3	10	16	26	2054.547
#276	BHLHE41	10	15	25	284.192
#277	ZNF80	10	19	29	717.074
#278	SPI1	10	13	23	553.356
#279	FOXD2	10	17	27	878.26
#280	ZNF287	10	16	26	1439.027
#281	ERF	10	17	27	5722.059
#282	HOXB7	10	15	25	1725.574
#283	ENO1	10	20	30	640.415
#284	HOXC8	10	15	25	11602.611
#285	MAFK	10	17	27	550.401
#286	HDX	10	14	24	1468.956
#287	LHX9	10	17	27	3841.308
#288	ZFPM2	10	11	21	569.896
#289	PTH	9	19	28	1450.122
#290	ETV3	9	18	27	558.927
#291	MSX2	9	17	26	418.609
#292	ETV1	9	16	25	1433.461
#293	TBX5	9	17	26	580.85
#294	PURB	9	13	22	874.776
#295	HIC1	9	16	25	370.41
#296	NFE2L2	9	19	28	609.116
#297	HOXD11	9	15	24	1102.049
#298	MYT1	9	16	25	2093.228
#299	BCL11B	9	22	31	12604.148
#300	ZEB2	9	15	24	701.102
#301	ZSCAN4	9	20	29	1535.929
#302	NR2E1	9	20	29	1495.324
#303	NR6A1	9	18	27	2653.07
#304	FOXR2	9	14	23	574.848
#305	NRL	9	13	22	236.665
#306	FOXS1	9	19	28	1089.942
#307	ZFHX4	9	15	24	542.547
#308	ZIC5	9	12	21	602.955
#309	NKX6-2	9	18	27	1144.688
#310	FOXN4	9	19	28	1056.009
#311	NFAT5	9	15	24	1277.9
#312	PRRX1	9	12	21	1714.142
#313	POU3F3	9	17	26	291.492
#314	BRD8	9	21	30	3614.994
#315	NR4A3	9	16	25	1781.325
#316	MLL	9	18	27	691.175
#317	LEF1	9	17	26	1028.92
#318	FOS	9	2	11	325.802
#319	CEBPE	9	20	29	1193.726
#320	SPIC	9	18	27	3009.209
#321	IRX4	8	12	20	714.474
#322	MEOX2	8	18	26	1266.685
#323	HOXB8	8	13	21	448.3
#324	SOX4	8	18	26	1005.473
#325	HIRA	8	16	24	899.999
#326	NR5A2	8	17	25	995.939
#327	DMBX1	8	9	17	995.82
#328	ATF2	8	17	25	646.668
#329	ONECUT2	8	16	24	634.775
#330	TWIST2	8	16	24	1696.33
#331	PRDM2	8	20	28	1638.127
#332	RARG	8	13	21	554.837
#333	ATOH1	8	15	23	468.671
#334	TFAP2B	8	15	23	1170.483
#335	HSF5	8	15	23	745.728
#336	PAX7	8	16	24	2399.545
#337	ZNF639	8	17	25	2418.96
#338	PHOX2B	8	14	22	706.411
#339	SP140	8	14	22	1673.332
#340	ESRRB	8	20	28	2050.304
#341	CREBBP	8	18	26	843.693
#342	BLZF1	8	14	22	1657.521
#343	HMX2	8	14	22	378.277
#344	CREB3L3	8	16	24	952.539
#345	DLX1	8	14	22	849.334
#346	GSX1	8	14	22	1692.929
#347	FOXM1	8	17	25	477.656
#348	TGIF2LY	8	21	29	1301.674
#349	ISX	8	19	27	728.519
#350	DMRT1	8	20	28	1631.489
#351	RCAN1	8	13	21	2128.985
#352	ALX4	8	15	23	981.78
#353	STAT5B	8	18	26	1264.984
#354	TEAD4	8	19	27	3172.722
#355	GATA5	8	18	26	1213.07
#356	ZNF131	8	21	29	1479.457
#357	GLI3	8	16	24	1197.769
#358	ZNF41	8	15	23	619.052
#359	ZEB1	7	15	22	624.619
#360	NFYA	7	15	22	607.933
#361	SIX6	7	18	25	2071.975
#362	TBX2	7	22	29	738.394
#363	ARNT2	7	16	23	300.716
#364	HOXA3	7	17	24	646.803
#365	SOX18	7	17	24	541.283
#366	TBX20	7	18	25	4016.319
#367	TFEC	7	19	26	561.905
#368	NFATC2	7	17	24	631.896
#369	SALL1	7	17	24	635.208
#370	PAX4	7	14	21	547.411
#371	HOXA2	7	19	26	1076.942
#372	ZNF167	7	19	26	1320.092
#373	ZNF396	7	18	25	1087.346
#374	KLF12	7	16	23	664.35
#375	HOXA7	7	12	19	695.673
#376	TBR1	7	16	23	1551.588
#377	FOXI1	7	16	23	783.041
#378	HOXB1	7	17	24	496.731
#379	ZNF643	7	11	18	736.653
#380	EGR1	7	8	15	1088.452
#381	TULP4	7	19	26	1026.189
#382	PAX6	7	16	23	1308.189
#383	POU1F1	7	15	22	720.781
#384	TSC22D3	7	12	19	728.305
#385	SRY	7	15	22	2437.425
#386	PAX3	7	14	21	360.075
#387	FOSL1	7	18	25	927.285
#388	POU4F2	7	17	24	540.064
#389	VAX2	7	21	28	881.435
#390	RUNX1T1	7	13	20	239.062
#391	SPIB	7	16	23	614.518
#392	TSC22D2	7	14	21	888.939
#393	SOX5	7	11	18	2266.183
#394	TP63	7	23	30	2323.525
#395	HOXD3	7	17	24	1130.438
#396	HIF3A	6	14	20	89.673
#397	EGR3	6	9	15	321.905
#398	FOSB	6	10	16	167.49
#399	LASS5	6	18	24	1631.391
#400	NKX2-3	6	12	18	1791.977
#401	SP4	6	16	22	686.721
#402	FOXE1	6	21	27	736.722
#403	LHX2	6	13	19	780.957
#404	TLX3	6	18	24	578.556
#405	PLSCR1	6	16	22	396.807
#406	HOXA13	6	18	24	1441.157
#407	CTBP1	6	17	23	491.072
#408	FLI1	6	18	24	1136.486
#409	RELA	6	17	23	595.39
#410	POU3F2	6	22	28	3178.694
#411	GSC2	6	13	19	644.225
#412	CSRNP3	6	22	28	843.315
#413	KLF9	6	18	24	1259.629
#414	PGR	6	17	23	746.017
#415	ZNF135	6	17	23	638.085
#416	NKX6-1	6	13	19	95.103
#417	PPARD	6	20	26	1195.64
#418	HOXD8	6	17	23	1370.214
#419	GATA3	6	17	23	916.003
#420	ELK4	6	16	22	420.889
#421	GBX2	6	16	22	272.621
#422	RERE	6	11	17	176.512
#423	ATF3	6	9	15	1063.198
#424	HNRNPAB	6	19	25	1213.764
#425	FOXD3	6	20	26	746.126
#426	PITX2	6	11	17	250.878
#427	ZIC3	6	14	20	1945.339
#428	SIX3	6	13	19	432.4
#429	ZNF85	6	14	20	410.13
#430	ZIC1	6	19	25	643.611
#431	GCM1	6	11	17	1764.606
#432	HOXA1	6	16	22	589.988
#433	TFE3	6	13	19	219.79
#434	ZNF92	6	17	23	654.321
#435	ONECUT3	6	20	26	933.379
#436	EN2	6	16	22	1682.143
#437	TCF3	5	16	21	402.906
#438	OLIG2	5	20	25	1110.342
#439	BNC1	5	22	27	519.226
#440	IKZF3	5	13	18	219.535
#441	ARNT	5	18	23	646.243
#442	PCGF2	5	12	17	110.004
#443	SATB2	5	14	19	666.072
#444	HOXB9	5	16	21	416.545
#445	ZNF90	5	14	19	389.727
#446	HMGA2	5	18	23	521.478
#447	WNT5A	5	20	25	527.606
#448	ELK1	5	19	24	378.377
#449	SRF	5	17	22	317.871
#450	NPAT	5	18	23	724.32
#451	C2orf3	5	24	29	1364.588
#452	NFKB2	5	18	23	721.97
#453	GLI2	5	17	22	2541.172
#454	SOX6	5	11	16	518.958
#455	MITF	5	20	25	847.454
#456	SOX30	5	16	21	1480.792
#457	ONECUT1	5	17	22	641.102
#458	ANKRD30A	5	24	29	1015.818
#459	WT1	5	18	23	1366.024
#460	NR5A1	5	20	25	556.099
#461	ZFP36L1	4	15	19	605.061
#462	POU5F2	4	19	23	980.771
#463	ZIC2	4	20	24	874.951
#464	RARA	4	15	19	1188.411
#465	ESR2	4	13	17	452.333
#466	LMX1A	4	13	17	250.318
#467	HMG20B	4	14	18	359.954
#468	ZNF154	4	20	24	553.27
#469	MYF5	4	16	20	793.315
#470	MSC	4	13	17	184.516
#471	DLX6	4	23	27	455.969
#472	MECOM	4	15	19	257.569
#473	LHX8	4	20	24	372.516
#474	EPAS1	4	23	27	856.468
#475	GRHL3	4	16	20	829.611
#476	SIM1	4	19	23	332.384
#477	GSX2	4	14	18	296.231
#478	SLC2A4RG	4	18	22	1612.862
#479	ZFP42	4	14	18	96.731
#480	HOXB6	4	19	23	585.409
#481	POU2F1	3	16	19	220.215
#482	C12orf28	3	17	20	867.807
#483	IRF4	3	20	23	693.711
#484	DLX2	3	18	21	629.483
#485	SIN3A	3	20	23	412.747
#486	SIM2	3	22	25	517.504
#487	FOXD1	3	23	26	2475.919
#488	TCF21	3	14	17	866.717
#489	SOX11	3	22	25	463.636
#490	POU4F3	3	20	23	583.687
#491	FOXJ2	3	15	18	208.955
#492	DLX3	2	17	19	228.26
#493	NEUROD2	2	18	20	521.948
#494	ZNF207	2	20	22	529.654
#495	STRN3	2	20	22	442.898
#496	MYT1L	2	14	16	882.658
#497	HOXD4	2	19	21	340.854
#498	TBX22	2	16	18	274.162
#499	NR0B1	1	20	21	165.835
#500	ZNF397	0	15	15	0