Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HIF3A	49	2	51	1507.919
#2	GSX1	44	1	45	201.253
#3	SPIB	36	4	40	680.141
#4	NR6A1	36	4	40	336.63
#5	FOXF2	36	5	41	4655.09
#6	ZHX2	35	3	38	3461.488
#7	HMGA1	34	7	41	576.617
#8	FOXM1	31	6	37	2781.413
#9	TFAP4	31	6	37	1827.973
#10	STAT5B	31	7	38	389.397
#11	HMGB1	30	2	32	398.073
#12	MAX	29	6	35	1623.235
#13	ZNF154	29	6	35	6395.265
#14	NR2C1	29	6	35	1186.912
#15	ONECUT2	28	4	32	1820.217
#16	KLF12	27	5	32	5860.047
#17	RORC	26	6	32	1115.442
#18	SOX10	26	6	32	317.449
#19	GATAD2B	26	1	27	62.212
#20	TBX3	25	6	31	343.756
#21	ATF4	24	2	26	268.565
#22	TBX20	24	8	32	892.056
#23	ARNT	24	1	25	16.729
#24	KLF2	23	11	34	1914.19
#25	VDR	23	3	26	438.471
#26	PURB	23	12	35	1887.462
#27	RXRB	23	8	31	484.857
#28	HMBOX1	22	5	27	1041.243
#29	NFIX	21	8	29	252.251
#30	TRPS1	21	11	32	1914.079
#31	MSL3	21	4	25	2494.095
#32	TCF25	21	8	29	4676.168
#33	BHLHE41	21	4	25	782.957
#34	ASCL1	20	9	29	1489.983
#35	ZEB2	20	5	25	4642.581
#36	KLF15	20	11	31	781.878
#37	TEF	20	10	30	564.024
#38	SIM2	20	5	25	1007.305
#39	ZNF187	20	6	26	1355.429
#40	ZNF281	20	4	24	607.52
#41	FOXO1	19	4	23	1038.752
#42	NFX1	19	9	28	1772.26
#43	AFF1	19	7	26	1354.029
#44	E2F4	19	5	24	537.392
#45	MEF2C	19	5	24	313.844
#46	NKX1-1	18	5	23	177.652
#47	ZNF396	18	7	25	826.025
#48	MBD1	18	9	27	504.218
#49	PAX8	17	2	19	46.155
#50	MMP14	17	9	26	655.762
#51	ZNF394	17	8	25	998.015
#52	RBPJL	17	8	25	813.118
#53	E2F1	17	4	21	207.192
#54	TP73	16	4	20	87.14
#55	KLF10	16	9	25	2541.759
#56	BNC1	16	9	25	2481.516
#57	TFAP2D	16	5	21	507.34
#58	FOXN3	16	6	22	4782.126
#59	ELK1	16	7	23	685.844
#60	LMX1B	15	9	24	329.834
#61	MEIS1	15	7	22	9123.612
#62	MYF6	15	6	21	597.58
#63	NKX3-1	15	12	27	1809.258
#64	E2F3	15	5	20	1090.568
#65	SMAD5	15	7	22	679.412
#66	RAX	15	4	19	49.939
#67	GATA4	14	4	18	393.43
#68	HNF1B	14	10	24	3322.245
#69	TP63	14	9	23	807.984
#70	POU6F1	14	6	20	410.464
#71	VAV1	14	12	26	5772.433
#72	KLF7	14	3	17	127.004
#73	LHX9	14	11	25	3792.37
#74	PRDM1	14	8	22	3480.562
#75	FOXH1	14	8	22	746.409
#76	NOTCH1	14	4	18	117.289
#77	TLX3	14	3	17	169.458
#78	MTF1	14	6	20	1720.757
#79	RCAN1	13	7	20	777.605
#80	KLF9	13	10	23	1782.581
#81	ZNF445	13	7	20	769.015
#82	ZNF19	13	11	24	1048.077
#83	NFYC	13	9	22	961.256
#84	PRDM2	13	3	16	57.195
#85	SOX12	13	6	19	933.662
#86	ZNF397	13	9	22	1087.126
#87	NR2F6	13	5	18	1070.271
#88	STAT4	13	7	20	487.588
#89	MLX	13	5	18	50.686
#90	TFCP2	13	7	20	743.957
#91	ZEB1	13	5	18	278.645
#92	UHRF1	12	5	17	764.665
#93	TAF5	12	9	21	2680.311
#94	LASS2	12	4	16	800.665
#95	MAF	12	10	22	6226.501
#96	POU3F2	12	8	20	3208.167
#97	TRIM22	12	7	19	1815.44
#98	MLLT10	12	7	19	16724.213
#99	NANOGNB	12	7	19	295.407
#100	PA2G4	12	6	18	2857.828
#101	RUNX2	12	10	22	974.899
#102	TEAD2	12	5	17	575.326
#103	TSHZ1	12	10	22	819.695
#104	CSRNP2	12	7	19	1835.304
#105	C5orf41	12	10	22	472.004
#106	ARNT2	12	11	23	2245.164
#107	GAS7	12	9	21	1353.046
#108	POU2F2	11	13	24	1102.12
#109	ZSCAN1	11	3	14	301.041
#110	TCF20	11	6	17	1084.472
#111	NR1I3	11	7	18	1416.534
#112	MTA1	11	6	17	1537.915
#113	ZNF207	11	8	19	2314.171
#114	MYT1	11	10	21	1978.112
#115	ELF2	11	10	21	1244.677
#116	FOXP1	11	6	17	1321.276
#117	C11orf9	11	9	20	8929.817
#118	NKX2-8	11	6	17	125.692
#119	TCF21	11	5	16	203.943
#120	FOXD3	10	7	17	9707.647
#121	CUX1	10	5	15	380.315
#122	TFAM	10	8	18	1414.277
#123	DDIT3	10	6	16	291.521
#124	RUNX1T1	10	13	23	2669.76
#125	ESRRA	10	12	22	998.352
#126	ETV1	10	7	17	250.654
#127	SPEN	10	8	18	333.511
#128	RFXANK	10	11	21	5435.365
#129	ELK3	10	11	21	2458.894
#130	ETS1	10	4	14	780.44
#131	EHF	10	10	20	2399.956
#132	HLF	10	9	19	1199.296
#133	RERE	10	8	18	607.72
#134	GLI3	10	13	23	3187.744
#135	CREBBP	10	6	16	1215.031
#136	HOPX	10	12	22	2986.266
#137	PAX5	10	9	19	510.125
#138	TCF15	10	6	16	499.102
#139	ZNF167	10	5	15	388.649
#140	IRF6	10	6	16	164.721
#141	MECOM	10	8	18	611.105
#142	ST18	10	9	19	717.178
#143	ZSCAN23	10	9	19	280.756
#144	ZNF75D	10	7	17	1920.722
#145	MITF	10	4	14	143.451
#146	GABPB1	10	7	17	657.29
#147	TADA3	10	7	17	376.598
#148	MTA3	9	5	14	141.761
#149	SOX17	9	9	18	1136.963
#150	WNT5A	9	10	19	2899.938
#151	KCNH8	9	15	24	2861.526
#152	ELF3	9	7	16	3001.691
#153	NEUROD2	9	6	15	150.074
#154	HOXB3	9	12	21	3123.173
#155	NFE2L1	9	8	17	190.187
#156	LHX3	9	9	18	2127.366
#157	ZKSCAN2	9	7	16	623.487
#158	IRF1	9	6	15	1878.762
#159	ZNF140	9	7	16	1562.832
#160	ZHX1	9	8	17	1992.635
#161	ZNF287	9	7	16	1579.764
#162	IRF2	9	8	17	734.701
#163	ZNF238	9	12	21	2084.345
#164	TCF7	9	7	16	270.597
#165	TCEAL1	9	6	15	304.431
#166	SOX8	9	5	14	403.301
#167	TCF12	9	7	16	652.364
#168	ZNF92	9	7	16	916.344
#169	FOXE1	9	13	22	2416.356
#170	EGR4	9	6	15	400.48
#171	TCF4	8	7	15	1476.582
#172	HDX	8	8	16	195.797
#173	TWIST2	8	12	20	21263.389
#174	TFDP2	8	7	15	202.073
#175	KLF4	8	8	16	1333.941
#176	ZFPM2	8	13	21	969.071
#177	USF2	8	7	15	1379.688
#178	MEF2D	8	9	17	985.099
#179	ZNF93	8	3	11	389.805
#180	GATA6	8	7	15	1252.185
#181	LMO4	8	6	14	207.02
#182	ZIC1	8	13	21	3277.504
#183	NFATC2	8	8	16	366.956
#184	TWIST1	8	9	17	5173.778
#185	ZNF189	8	5	13	114.865
#186	MAFK	8	8	16	1662.825
#187	ZNF193	8	9	17	559.07
#188	CIR1	8	7	15	433.202
#189	PHF1	8	8	16	580.839
#190	MLXIPL	8	8	16	887.309
#191	BCL6	8	6	14	2097.338
#192	ZNF45	8	6	14	727.03
#193	IRF9	8	7	15	377.998
#194	ERG	8	13	21	834.373
#195	CREB3L2	8	5	13	422.351
#196	NFIA	8	13	21	1590.446
#197	PLSCR1	8	9	17	1411.035
#198	NR3C1	8	10	18	2406.671
#199	ONECUT1	8	11	19	1100.8
#200	ZNF3	8	5	13	232.054
#201	RFX5	8	4	12	184.931
#202	LHX2	7	6	13	242.568
#203	MEIS2	7	9	16	3396.754
#204	KDM5A	7	9	16	1429.357
#205	HAND1	7	6	13	408.266
#206	ZNF277	7	9	16	1408.957
#207	TBR1	7	7	14	2123.27
#208	E2F7	7	5	12	642.783
#209	HOXB7	7	9	16	146.094
#210	MEOX1	7	13	20	2821.733
#211	ZNF628	7	6	13	259.177
#212	BCL3	7	10	17	3508.698
#213	MYCL1	7	15	22	6580.493
#214	FOXK2	7	5	12	557.845
#215	NFATC4	7	7	14	283.221
#216	HOXA10	7	7	14	533.946
#217	EPAS1	7	10	17	1577.583
#218	CREBL2	7	6	13	490.976
#219	ZSCAN12	7	11	18	761.494
#220	FOXA2	7	7	14	6037.835
#221	PBX3	7	10	17	282.378
#222	MGA	7	9	16	814.458
#223	HMGA2	7	14	21	6015.477
#224	BACH1	7	3	10	56.648
#225	NRL	7	10	17	323.882
#226	NOLC1	7	7	14	1351.374
#227	HOXA7	7	9	16	4659.267
#228	HOXA5	7	7	14	328.03
#229	NANOG	7	10	17	1243.59
#230	KDM5B	7	9	16	502.928
#231	FOXQ1	7	8	15	1123.805
#232	SMAD3	7	5	12	334.958
#233	PEG3	7	4	11	595.209
#234	LHX8	7	8	15	3133.759
#235	ZNF83	7	10	17	1443.189
#236	TBP	7	5	12	155.867
#237	FOXJ2	7	6	13	813.4
#238	ETV3	7	7	14	361.271
#239	JUNB	7	6	13	633.995
#240	AHR	6	9	15	2114.912
#241	EGR3	6	4	10	352.457
#242	VAX2	6	16	22	883.7
#243	ZNF35	6	13	19	283.166
#244	ETV5	6	5	11	354.72
#245	TGIF2	6	12	18	2578.526
#246	ATF7	6	6	12	900.123
#247	MAFF	6	15	21	9274.861
#248	HMX1	6	7	13	487.947
#249	E2F8	6	10	16	950.887
#250	HSF1	6	6	12	266.983
#251	TAF10	6	6	12	939.966
#252	XBP1	6	9	15	753.954
#253	SNAI2	6	7	13	1403.049
#254	CNOT7	6	9	15	278.706
#255	TAF4B	6	6	12	1453.498
#256	PBX1	6	6	12	2494.748
#257	TCF3	6	7	13	1498.6
#258	MXD1	6	8	14	234.042
#259	ATF1	6	8	14	1922.06
#260	NR0B1	6	7	13	800.839
#261	ZIC2	6	12	18	4559.736
#262	IRX3	6	12	18	2123.831
#263	HOXB6	6	5	11	4857.846
#264	KLF6	6	9	15	3712.528
#265	HCLS1	6	5	11	807.973
#266	ZNF268	6	7	13	2244.962
#267	MSRB2	6	10	16	1055.312
#268	GATA5	6	11	17	240.173
#269	DMRT1	6	5	11	511.163
#270	RARB	6	3	9	89.222
#271	ARX	6	11	17	543.005
#272	WT1	6	12	18	2331.918
#273	KLF3	6	5	11	231.513
#274	JUN	6	10	16	719.542
#275	MEF2A	6	5	11	626.7
#276	ZNF165	6	11	17	1619.907
#277	SCML1	6	15	21	1375.683
#278	AR	6	10	16	2326.872
#279	ZNF202	6	11	17	511.058
#280	NFE2L3	6	10	16	154.696
#281	ZSCAN20	6	10	16	1218.732
#282	SLC30A9	6	7	13	682.581
#283	SOX6	6	9	15	328.478
#284	ESR1	5	8	13	1303.006
#285	STAT3	5	6	11	336.632
#286	NPAS2	5	16	21	5574.204
#287	FOSL2	5	9	14	1989.284
#288	GRHL2	5	7	12	485.012
#289	TCFL5	5	6	11	437.466
#290	TFEC	5	8	13	857.412
#291	HOXD10	5	12	17	2047.847
#292	BACH2	5	9	14	617.205
#293	MNX1	5	9	14	1239.518
#294	SOX5	5	10	15	850.205
#295	CITED2	5	7	12	2249.989
#296	IKZF1	5	12	17	1678.568
#297	NFYB	5	8	13	1375.55
#298	ZNF37A	5	10	15	560.249
#299	RUNX1	5	5	10	731.806
#300	TCF7L2	5	11	16	1564.267
#301	ENO1	5	7	12	567.848
#302	SOX4	5	9	14	291.826
#303	NR4A1	5	13	18	2188.91
#304	GLIS3	5	12	17	1283.73
#305	HEY1	5	8	13	949.007
#306	MYCN	5	10	15	439.601
#307	FLI1	5	4	9	79.877
#308	L3MBTL4	5	9	14	1117.969
#309	ELF1	5	5	10	568.848
#310	SIX4	5	13	18	538.416
#311	PAX6	5	11	16	1887.251
#312	ESRRG	5	9	14	1136.118
#313	PGBD1	5	5	10	511.308
#314	ATF2	5	8	13	299.552
#315	RBCK1	5	7	12	491.217
#316	HOXA2	5	11	16	3381.847
#317	ZNF232	5	8	13	331.969
#318	ZXDC	5	7	12	586.722
#319	VSX1	5	9	14	625.904
#320	KLF5	5	14	19	2929.123
#321	GTF2H3	5	8	13	587.033
#322	BCL11B	5	4	9	91.526
#323	OLIG2	5	5	10	76.934
#324	MEOX2	5	11	16	581.353
#325	PPARG	5	7	12	823.017
#326	SOX11	5	11	16	7215.214
#327	ETV6	5	7	12	834.539
#328	TFE3	5	4	9	241.625
#329	ZNF367	5	7	12	475.26
#330	NR3C2	5	11	16	537.73
#331	HOXC10	5	8	13	491.155
#332	FOXD1	5	8	13	1962.604
#333	ZFP42	5	7	12	1908.585
#334	IRF8	5	9	14	588.577
#335	ZNF213	5	8	13	216.578
#336	FOSB	5	10	15	1264.519
#337	HOXB5	5	6	11	1121.916
#338	YEATS4	5	11	16	1803.014
#339	GATA1	4	9	13	2272.676
#340	ETS2	4	9	13	128.92
#341	ZNF175	4	7	11	1496.724
#342	NR5A2	4	12	16	1670.37
#343	SP1	4	9	13	573.077
#344	TBX10	4	7	11	202.505
#345	HEYL	4	7	11	200.984
#346	HOXD8	4	6	10	302.594
#347	PRRX1	4	8	12	204.368
#348	HOXB4	4	9	13	406.549
#349	AEBP1	4	7	11	430.304
#350	EBF1	4	7	11	569.459
#351	POU3F1	4	8	12	144.723
#352	GLIS2	4	11	15	405.934
#353	NFIB	4	10	14	2361.361
#354	PLAG1	4	12	16	2771.576
#355	HOXA9	4	9	13	3386.297
#356	CTNNB1	4	10	14	2071.187
#357	SALL1	4	12	16	1702.979
#358	SMAD9	4	6	10	270.134
#359	ZNF131	4	8	12	265.667
#360	NFIL3	4	9	13	771.004
#361	SMAD4	4	9	13	176.823
#362	HOXA11	4	6	10	97.829
#363	RFXAP	4	7	11	769.023
#364	CUX2	4	4	8	385.513
#365	SOX13	4	9	13	97.684
#366	ZNF91	4	10	14	702.302
#367	HESX1	4	6	10	234.357
#368	CREM	4	8	12	927.554
#369	TLX2	4	11	15	966.62
#370	ZNF148	4	7	11	367.452
#371	ETV4	4	9	13	1679.287
#372	TRIM28	4	9	13	510.593
#373	POU2F3	4	9	13	1182.345
#374	PTTG1	4	8	12	498.364
#375	SIX3	4	10	14	2523.765
#376	LZTS1	4	13	17	1155.765
#377	TSHZ3	4	13	17	519.201
#378	CSRNP3	4	9	13	397.021
#379	SP3	4	11	15	177.625
#380	ZNF483	4	9	13	360.381
#381	CEBPD	3	9	12	767.462
#382	HES1	3	9	12	9948.462
#383	GATA2	3	10	13	2402.438
#384	ZNF496	3	7	10	433.142
#385	GSX2	3	9	12	364.645
#386	MYT1L	3	10	13	196.464
#387	STAT1	3	10	13	189.087
#388	SIX1	3	14	17	371.888
#389	FOXG1	3	18	21	1179.414
#390	TBX21	3	11	14	485.391
#391	ZNF33B	3	14	17	474.436
#392	FOS	3	9	12	1186.588
#393	FOXL2	3	10	13	299.138
#394	NR4A3	3	8	11	162.69
#395	CREB5	3	11	14	400.646
#396	ZNF85	3	6	9	405.919
#397	HEY2	3	10	13	548.076
#398	ZSCAN18	3	8	11	1737.991
#399	EGR1	3	5	8	530.978
#400	ZNF71	3	8	11	95.429
#401	EGR2	3	11	14	2160.376
#402	HOXB2	3	6	9	971.603
#403	C12orf28	3	7	10	477.215
#404	PROX1	3	10	13	158.012
#405	NFYA	3	12	15	663.874
#406	SOX9	3	10	13	392.582
#407	MSX1	3	14	17	1846.392
#408	ZNF639	3	10	13	231.64
#409	MEIS3P1	3	5	8	129.993
#410	CDKN2A	3	14	17	1294.984
#411	TFDP3	3	4	7	570.741
#412	STAT6	3	7	10	173.252
#413	RBPJ	3	4	7	88.528
#414	FUBP1	3	13	16	306.286
#415	NR1D2	3	4	7	49.485
#416	HOXB8	3	10	13	1464.092
#417	ERF	3	9	12	183.55
#418	KLF16	3	9	12	528.013
#419	RORA	3	10	13	275.884
#420	HOXD3	3	5	8	257.142
#421	NCOR1	3	7	10	2247.354
#422	HOXB1	3	6	9	127.079
#423	CSRNP1	2	9	11	263.192
#424	GATAD2A	2	10	12	198.931
#425	TSHZ2	2	9	11	1182.018
#426	TFAP2C	2	15	17	879.226
#427	ATF3	2	7	9	1998.929
#428	FOXA1	2	6	8	68.972
#429	ZNF80	2	11	13	133.494
#430	FOXO6	2	10	12	2906.611
#431	HOXA3	2	12	14	4560.605
#432	HOXC9	2	9	11	92.858
#433	BLZF1	2	7	9	1125.143
#434	CTBP1	2	7	9	48.6
#435	CREBZF	2	7	9	617.249
#436	MYC	2	9	11	206.57
#437	STAT5A	2	4	6	22.52
#438	HOXA6	2	7	9	53.838
#439	MAFB	2	12	14	3704.498
#440	HOXD1	2	9	11	818.054
#441	LHX1	2	10	12	211.197
#442	HNF4A	2	13	15	262.526
#443	HIRA	2	7	9	50.15
#444	SIX2	2	9	11	192.584
#445	HOXD4	2	11	13	359.262
#446	NFATC1	2	10	12	120.297
#447	IRF5	2	8	10	42.96
#448	PPARA	2	8	10	126.353
#449	ZNF236	2	9	11	79.713
#450	ZNF117	2	8	10	1048.355
#451	AFF4	2	9	11	1096.292
#452	SOX7	2	10	12	39.949
#453	IRX2	2	7	9	63.069
#454	TSC22D2	2	11	13	88.297
#455	FOXJ3	2	5	7	66.466
#456	BHLHE40	2	8	10	442.836
#457	SREBF1	2	6	8	1204.414
#458	DLX6	2	15	17	884.598
#459	RFX3	2	7	9	260.533
#460	TSC22D3	2	7	9	195.871
#461	PTH	2	6	8	303.282
#462	SMAD6	2	9	11	1056.354
#463	NR2F2	2	12	14	364.788
#464	ZNF24	2	7	9	202.187
#465	SCRT1	2	9	11	736.272
#466	LEF1	1	13	14	132.818
#467	FOXP2	1	8	9	931.823
#468	TFDP1	1	8	9	159.484
#469	ELF4	1	10	11	341.952
#470	RUNX3	1	16	17	932.354
#471	PGR	1	11	12	70.583
#472	TEAD4	1	12	13	844.225
#473	FOXC1	1	10	11	53.293
#474	GRHL3	1	12	13	133.021
#475	E2F5	1	8	9	227.197
#476	PITX2	1	10	11	1302.693
#477	ZNF70	1	8	9	90.191
#478	HOXC4	1	13	14	151.286
#479	RXRA	1	11	12	75.9
#480	POU1F1	1	13	14	536.971
#481	TFCP2L1	1	12	13	3310.469
#482	NR2F1	1	11	12	198.897
#483	FOXA3	1	10	11	481.517
#484	DMRT2	1	10	11	203.18
#485	FOXJ1	1	10	11	410.249
#486	THRB	1	9	10	117.84
#487	ZNF81	0	13	13	0
#488	SIX5	0	11	11	0
#489	SIM1	0	13	13	0
#490	GATA3	0	11	11	0
#491	SOX2	0	12	12	0
#492	MKX	0	12	12	0
#493	NR4A2	0	11	11	0
#494	ZNF169	0	10	10	0
#495	NPAT	0	7	7	0
#496	HHEX	0	7	7	0
#497	TFAP2A	0	9	9	0
#498	MYOG	0	5	5	0
#499	SPIC	0	6	6	0
#500	TP53	0	8	8	0