Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TCF7L1	59	2	61	258.299
#2	ZFP36L2	39	4	43	868.573
#3	FOSL2	38	5	43	863.19
#4	TCF3	37	9	46	1046.523
#5	RXRB	37	7	44	766.095
#6	ZNF446	35	9	44	1218.382
#7	TEAD1	35	12	47	1680.071
#8	NANOGNB	35	9	44	1354.942
#9	TSHZ2	34	9	43	1195.412
#10	NR4A2	32	12	44	1544.701
#11	ERF	32	8	40	811.097
#12	NFATC4	31	6	37	779.9
#13	GLIS3	31	10	41	1001.596
#14	LASS6	31	14	45	1821.777
#15	HSF2	30	8	38	818.589
#16	DMRT1	29	12	41	1395.892
#17	ZNF174	28	6	34	654.733
#18	ASCL1	28	14	42	1799.496
#19	SOX4	28	8	36	429.069
#20	POU2F1	27	22	49	2626.139
#21	PHOX2B	27	9	36	1195.922
#22	ZNF193	26	13	39	1621.155
#23	MMP14	26	4	30	169.61
#24	YY1	26	7	33	1156.636
#25	FOXQ1	25	11	36	1570.037
#26	TAF13	25	11	36	1496.692
#27	LHX5	25	11	36	1333.509
#28	ARNT2	25	12	37	844.378
#29	NFATC1	25	8	33	566.636
#30	ONECUT1	24	8	32	709.948
#31	RARA	24	15	39	1271.022
#32	HCFC1	24	7	31	835.943
#33	TCF21	24	10	34	1014.225
#34	ZSCAN18	24	13	37	1488.587
#35	SOX9	23	17	40	1383.235
#36	AHCTF1	23	11	34	1345.745
#37	KLF16	23	14	37	1369.157
#38	SPEN	23	10	33	852.602
#39	RFXAP	23	12	35	936.428
#40	KLF6	23	15	38	1653.584
#41	ZFP37	23	11	34	1457.517
#42	CEBPD	23	11	34	926.574
#43	KLF4	23	7	30	496.078
#44	ETV7	23	10	33	1453.278
#45	KLF1	22	11	33	1305.934
#46	MYC	22	8	30	966.449
#47	MSX1	22	15	37	1516.937
#48	ZFHX3	22	12	34	542.163
#49	ISX	22	12	34	1131.717
#50	ZNF148	22	12	34	1178.44
#51	NEUROG1	22	12	34	1442.243
#52	KLF12	22	13	35	1076.981
#53	MAFK	22	11	33	1175.664
#54	SPIC	22	13	35	1160.719
#55	ZNF287	22	13	35	1414.329
#56	ZNF238	22	13	35	1204.49
#57	MIXL1	22	15	37	1205.205
#58	MYCL1	22	11	33	991.071
#59	THRB	22	15	37	1494.751
#60	FOXN1	21	11	32	999.219
#61	MESP1	21	15	36	1397.012
#62	MYCN	21	10	31	962.55
#63	ELF5	21	10	31	1288.558
#64	HAND2	21	9	30	1434
#65	TRIM29	21	13	34	1118.267
#66	ZKSCAN3	21	12	33	1268.239
#67	FOXN4	21	8	29	837.062
#68	FOXH1	21	12	33	1564.915
#69	RFX1	21	10	31	868.31
#70	NFYC	20	14	34	1434.383
#71	CREB5	20	12	32	799.64
#72	FOXA2	20	13	33	1105.692
#73	FOSB	20	9	29	647.665
#74	RUNX2	20	15	35	1163.298
#75	FOXP1	20	10	30	841.762
#76	HOXA10	20	10	30	1000.303
#77	TAF10	20	21	41	1717.326
#78	DMRT2	20	15	35	1489.376
#79	HIRA	19	10	29	804.868
#80	VAX2	19	15	34	1733.112
#81	SOX18	19	20	39	1517.974
#82	CDKN2A	19	12	31	1054.529
#83	ATF6B	19	12	31	1180.264
#84	HOXB9	19	10	29	954.467
#85	POU6F1	19	10	29	805.913
#86	EN1	19	16	35	1177.419
#87	ZNF165	19	14	33	1391.225
#88	NKX2-3	19	8	27	650.524
#89	NFIX	19	13	32	1391.763
#90	ZFHX4	19	14	33	1092.721
#91	NFX1	19	12	31	945.461
#92	ELF3	18	12	30	1234.557
#93	ZNF33A	18	10	28	909.296
#94	BARX1	18	17	35	1408.427
#95	EVX1	18	10	28	977.686
#96	NPAS2	18	11	29	804.985
#97	HOXA9	18	8	26	726.721
#98	PROX1	18	12	30	790.512
#99	HOXD12	18	13	31	1041.615
#100	GRHL2	18	9	27	998.898
#101	PBX1	18	12	30	834.099
#102	SHOX	18	11	29	930.048
#103	PHTF1	18	14	32	1083.704
#104	TCF7L2	18	12	30	996.07
#105	PPARG	18	16	34	1214.793
#106	FUBP1	18	12	30	737.077
#107	LMX1B	18	11	29	708.572
#108	GATA3	17	13	30	673.672
#109	SOX30	17	13	30	1437.72
#110	KLF9	17	14	31	994.735
#111	HOXD9	17	12	29	1023.536
#112	PDX1	17	10	27	1188.433
#113	FOXB1	17	11	28	831.407
#114	ZFHX2	17	15	32	1057.312
#115	ZNF169	17	12	29	945.997
#116	FOXR2	17	14	31	1524.992
#117	SMAD2	17	18	35	1488.358
#118	KDM5B	17	13	30	792.757
#119	ZIC5	17	13	30	1037.435
#120	NFIA	17	17	34	1373.765
#121	TLX1	17	13	30	906.902
#122	NKX6-1	17	16	33	1170.143
#123	HNF1A	17	13	30	919.869
#124	LEF1	17	13	30	1181.428
#125	BRD8	17	16	33	1297.749
#126	HOXB6	17	7	24	710.518
#127	MNX1	17	13	30	921.795
#128	TGIF1	17	14	31	892.278
#129	RBPJL	17	8	25	709.244
#130	DLX4	17	13	30	977.778
#131	HLF	17	13	30	1064.151
#132	JUND	16	14	30	886.595
#133	SIN3A	16	14	30	940.715
#134	NR0B1	16	8	24	405.859
#135	SNAPC5	16	9	25	768.051
#136	SOX21	16	8	24	753.777
#137	CUX2	16	16	32	1015.909
#138	MSRB2	16	16	32	879.677
#139	BCL11B	16	19	35	1241.03
#140	NKX2-1	16	15	31	1291.011
#141	FOXO1	16	11	27	843.853
#142	RUNX1	16	17	33	1226.139
#143	POU3F4	16	10	26	741.784
#144	LHX2	16	12	28	599.215
#145	SP3	16	10	26	958.879
#146	ERG	16	10	26	810.71
#147	FOXK1	16	12	28	633.252
#148	EMX1	16	14	30	1135.117
#149	LMO4	16	17	33	1604.942
#150	IKZF1	16	9	25	743.624
#151	PAX4	16	15	31	1170.972
#152	USF1	16	12	28	859.556
#153	SOX1	16	11	27	930.216
#154	GATA4	16	8	24	495.524
#155	TAF4	16	14	30	904.843
#156	POU3F2	16	14	30	1118.362
#157	NPAT	16	12	28	1031.972
#158	NR1I3	16	14	30	1009.033
#159	MEIS1	16	16	32	766.988
#160	HESX1	16	11	27	818.996
#161	KLF17	16	13	29	1052.073
#162	ZNF167	16	12	28	936.192
#163	NR4A3	15	16	31	1312.61
#164	REST	15	12	27	851.973
#165	HOPX	15	12	27	903.099
#166	ZNF71	15	12	27	867.761
#167	GRHL3	15	12	27	973.118
#168	NR5A1	15	9	24	527.473
#169	TFDP3	15	18	33	1658.275
#170	SOX11	15	14	29	773.859
#171	TFAP2C	15	9	24	692.799
#172	CBL	15	11	26	642.316
#173	SOX10	15	9	24	446.702
#174	GAS7	15	14	29	662.075
#175	FOXA3	15	10	25	786.127
#176	FOXJ1	15	12	27	910.778
#177	PEG3	15	16	31	1083.277
#178	NFATC3	15	15	30	934.191
#179	TAL1	15	9	24	549.285
#180	HSF5	15	21	36	1564.83
#181	TGIF2LY	15	11	26	906.224
#182	VDR	15	11	26	858.845
#183	AFF1	15	13	28	758.716
#184	EHF	15	16	31	1116.105
#185	ZNF496	15	16	31	1037.58
#186	CBFA2T2	15	10	25	648.56
#187	MTA2	15	15	30	1032.678
#188	ISL1	15	13	28	1418.186
#189	SUPT6H	15	19	34	1440.68
#190	FOXR1	15	14	29	1130.226
#191	HES6	15	9	24	634.032
#192	TWIST2	15	19	34	1468.994
#193	GATAD2A	15	12	27	637.415
#194	TBX2	15	13	28	988.811
#195	HOXA2	15	16	31	1011.672
#196	RUNX3	15	16	31	1209.288
#197	POU3F1	15	12	27	794.154
#198	SMAD6	15	13	28	898.31
#199	SMAD1	15	15	30	1017.214
#200	EN2	15	15	30	1133.204
#201	STAT5B	15	11	26	684.197
#202	TBR1	15	14	29	1254.522
#203	PAX7	15	15	30	1275.085
#204	WNT5A	15	9	24	793.643
#205	MEIS3	15	13	28	879.469
#206	LASS5	14	14	28	1007.206
#207	VSX1	14	17	31	1277.281
#208	ZNF80	14	14	28	825.086
#209	FOSL1	14	12	26	732.265
#210	TFE3	14	12	26	1176.858
#211	TADA3	14	12	26	863.059
#212	SMAD9	14	12	26	726.229
#213	ZSCAN2	14	12	26	971.841
#214	ATF3	14	10	24	919.824
#215	TRERF1	14	15	29	831.702
#216	HOXA3	14	16	30	1053.325
#217	ZNF154	14	17	31	977.142
#218	HEY2	14	19	33	1370.61
#219	KCNH8	14	14	28	978.738
#220	ONECUT3	14	15	29	901.337
#221	IRX1	14	10	24	654.367
#222	FOXL1	14	13	27	938.481
#223	HMX2	14	13	27	1020.108
#224	CREB3L2	14	10	24	432.247
#225	FOXP3	14	11	25	728.489
#226	BLZF1	14	15	29	1172.636
#227	TFCP2L1	14	11	25	665.953
#228	TLX3	14	14	28	866.81
#229	NEUROD2	13	10	23	453.366
#230	ZNF215	13	15	28	823.394
#231	HOXD3	13	21	34	1331.768
#232	SOX8	13	13	26	538.497
#233	ZNF135	13	20	33	1206.529
#234	WT1	13	11	24	468.511
#235	ZNF90	13	12	25	699.169
#236	SMAD4	13	15	28	1103.081
#237	LMX1A	13	17	30	1141.263
#238	TEF	13	20	33	1085.036
#239	NEUROD1	13	15	28	1067.654
#240	IRX2	13	13	26	701.483
#241	RUNX1T1	13	20	33	798.559
#242	ZNF175	13	15	28	1078.39
#243	ZNF277	13	16	29	925.947
#244	NFE2	13	14	27	1049.028
#245	MYF5	13	12	25	942.873
#246	PAX3	13	19	32	1120.993
#247	ZNF132	13	16	29	918.338
#248	ZNF93	13	13	26	776.403
#249	IRX5	13	15	28	825.097
#250	CTBP1	13	15	28	958.375
#251	GLI2	13	14	27	966.92
#252	ZSCAN20	13	16	29	863.043
#253	PBX3	13	15	28	1285.242
#254	ELK1	13	14	27	952.465
#255	ATF7	13	15	28	973.704
#256	NR6A1	13	11	24	754.689
#257	NFATC2	13	16	29	771.52
#258	NR1I2	13	11	24	575.75
#259	CRX	13	13	26	1048.302
#260	MYF6	13	12	25	744.064
#261	HNF4A	13	14	27	967.779
#262	FOXD4	13	13	26	845.479
#263	NPAS1	13	20	33	1551.757
#264	PGBD1	13	15	28	803.108
#265	HNF1B	13	13	26	864.531
#266	HSF1	12	16	28	845.689
#267	SEBOX	12	12	24	424.856
#268	ZFP42	12	16	28	1297.151
#269	CLOCK	12	11	23	751.968
#270	HAND1	12	13	25	966.237
#271	HOXD10	12	14	26	722.476
#272	HOXA11	12	13	25	719.997
#273	AFF4	12	16	28	1104.443
#274	HDX	12	18	30	937.795
#275	PKNOX1	12	13	25	977.273
#276	TBX6	12	10	22	540.257
#277	PPARA	12	15	27	921.055
#278	TCF25	12	18	30	1180.822
#279	CSRNP3	12	15	27	941.77
#280	MGA	12	20	32	1197.387
#281	SRF	12	20	32	1000.477
#282	IRX4	12	14	26	666.714
#283	SCAND3	12	19	31	1300.847
#284	GCM1	12	13	25	753.099
#285	CREBBP	12	12	24	700.212
#286	RARB	12	14	26	889.03
#287	ESR2	12	15	27	912.145
#288	HMG20B	12	14	26	723.579
#289	SIX6	12	12	24	1041.426
#290	NKX6-2	12	10	22	863.217
#291	IRF5	12	9	21	519.108
#292	PCGF2	12	14	26	830.004
#293	ARX	12	12	24	741.039
#294	FOXE3	12	13	25	983.482
#295	FOXD1	12	12	24	782.262
#296	VTN	12	12	24	738.762
#297	AR	12	14	26	727.425
#298	NFIB	12	15	27	807.327
#299	ALS2CR8	12	15	27	771.313
#300	ZIC3	12	13	25	855.248
#301	FOXG1	11	17	28	824.952
#302	OTX1	11	12	23	598.058
#303	ALX4	11	17	28	911.46
#304	IRF6	11	15	26	659.639
#305	NFKB2	11	18	29	990.702
#306	ASCL2	11	18	29	978.012
#307	SRY	11	16	27	1051.698
#308	TSC22D3	11	16	27	908.082
#309	FOXD2	11	14	25	788.012
#310	LHX4	11	11	22	611.847
#311	GSX1	11	19	30	1242.909
#312	ETV2	11	13	24	711.53
#313	PRDM2	11	10	21	488.86
#314	ZSCAN12	11	18	29	919.663
#315	FOXC2	11	13	24	825.05
#316	ZNF75D	11	16	27	650.155
#317	HMGB2	11	10	21	386.885
#318	BHLHE41	11	16	27	1005.294
#319	OVOL1	11	14	25	545.713
#320	SP140	11	12	23	680.013
#321	POU5F2	11	13	24	818.386
#322	BNC1	11	13	24	768.114
#323	PPARD	11	15	26	535.079
#324	ZNF19	11	22	33	1315.014
#325	HOXC9	11	12	23	861.828
#326	RARG	11	13	24	722.831
#327	MLL	11	10	21	679.621
#328	FOXO3	11	12	23	533.08
#329	GSX2	11	9	20	511.713
#330	L3MBTL4	11	13	24	576.135
#331	ALX3	10	12	22	561.365
#332	NR2E1	10	12	22	580.65
#333	C11orf9	10	17	27	804.313
#334	TLX2	10	15	25	510.172
#335	DLX2	10	13	23	527.271
#336	CREB3L3	10	17	27	586.589
#337	GATAD1	10	14	24	1049.215
#338	TCF20	10	12	22	714.86
#339	ZNF3	10	13	23	832.637
#340	POU4F1	10	10	20	383.707
#341	ETV1	10	14	24	670.168
#342	NR2F6	10	18	28	937.585
#343	ZIC2	10	19	29	1018.171
#344	ESRRG	10	9	19	412.499
#345	RORC	10	12	22	572.627
#346	PAX8	10	16	26	754.287
#347	GSC2	10	14	24	624.305
#348	NR1H4	10	19	29	908.742
#349	FOXD3	10	16	26	946.46
#350	FOXK2	10	10	20	384.827
#351	ZNF81	10	14	24	696.208
#352	MXD1	10	6	16	293.381
#353	ELK4	10	10	20	467.798
#354	MITF	10	20	30	1143.589
#355	PGR	10	16	26	690.533
#356	ATF2	10	19	29	899.643
#357	LHX8	10	25	35	1179.318
#358	ETS2	10	11	21	437.163
#359	SOX2	10	17	27	781.962
#360	ZIC1	10	15	25	641.926
#361	DMBX1	10	15	25	803.271
#362	HOXD11	10	14	24	778.256
#363	TFAP2A	10	12	22	785.281
#364	SCRT1	9	14	23	685.525
#365	HOXD13	9	12	21	534.867
#366	SOX5	9	16	25	737.343
#367	RORB	9	18	27	766.856
#368	MYNN	9	17	26	865.392
#369	GLI3	9	17	26	608.983
#370	MYT1	9	13	22	592.545
#371	HMGA2	9	16	25	790.937
#372	MSX2	9	15	24	901.442
#373	MLXIPL	9	14	23	548.905
#374	ETV4	9	10	19	607.795
#375	SIM1	9	19	28	952.464
#376	TBX1	9	13	22	614.501
#377	RXRG	9	14	23	790.367
#378	TULP4	9	16	25	848.207
#379	TBX5	9	12	21	459.5
#380	ESR1	9	11	20	453.646
#381	ZNF219	9	14	23	693.479
#382	TCF12	9	15	24	438.253
#383	PKNOX2	9	11	20	406.211
#384	CREM	9	16	25	573.596
#385	DLX3	9	19	28	863.302
#386	FOXI1	9	14	23	522.177
#387	POU6F2	9	14	23	514.273
#388	OTX2	9	21	30	941.812
#389	FOXL2	9	22	31	982.215
#390	GBX2	9	22	31	1233.324
#391	ETV3	9	16	25	870.588
#392	EGR4	9	15	24	637.959
#393	SOX13	9	16	25	668.87
#394	LZTS1	9	16	25	775.426
#395	MLLT10	9	16	25	619.485
#396	FOXP2	9	14	23	548.173
#397	ZNF207	9	12	21	629.769
#398	HNRNPAB	9	14	23	834.788
#399	RORA	9	18	27	1069.816
#400	NKX2-8	9	10	19	565.468
#401	IRF4	9	13	22	427.29
#402	HR	9	14	23	864.141
#403	FOXE1	9	15	24	707.529
#404	KLF2	9	11	20	464.095
#405	HOXD1	9	12	21	403.187
#406	ATOH1	8	15	23	566.813
#407	SOX6	8	18	26	845.889
#408	PAX5	8	17	25	680.825
#409	HOXB8	8	16	24	628.789
#410	SIM2	8	18	26	715.477
#411	POU4F2	8	20	28	933.568
#412	ZSCAN4	8	13	21	474.284
#413	ZEB1	8	21	29	611.955
#414	SALL1	8	16	24	798.057
#415	MZF1	8	15	23	641.597
#416	SATB2	8	15	23	685.52
#417	PTH	8	15	23	930.57
#418	GATA5	8	15	23	545.691
#419	SIX4	8	14	22	582.177
#420	ZNF117	8	17	25	573.73
#421	HIC1	8	16	24	517.2
#422	HOXD4	8	16	24	749.652
#423	RCAN1	8	9	17	466
#424	PURB	8	15	23	516.335
#425	SLC2A4RG	8	17	25	842.227
#426	TP63	8	19	27	934.781
#427	NANOG	8	18	26	941.033
#428	ZSCAN10	8	19	27	642.065
#429	NR5A2	8	19	27	949.7
#430	THRA	8	16	24	558.621
#431	ZNF397	8	15	23	480.428
#432	SIX1	8	14	22	773.87
#433	ZNF131	8	17	25	585.401
#434	HIF3A	8	23	31	1031.847
#435	MAF	8	19	27	689.631
#436	ZNF483	8	14	22	517.446
#437	NRL	8	16	24	490.517
#438	SIX5	8	14	22	551.294
#439	HOXC13	7	16	23	480.403
#440	POU4F3	7	16	23	481.026
#441	CSDA	7	20	27	668.175
#442	ARNT	7	18	25	764.401
#443	ZNF33B	7	11	18	354.303
#444	SIX2	7	13	20	422.691
#445	DLX1	7	14	21	469.372
#446	DLX6	7	17	24	419.912
#447	ZFP36L1	7	16	23	649.333
#448	OLIG2	7	16	23	823.907
#449	NFYA	7	22	29	644.81
#450	TBX15	7	19	26	659.477
#451	SIX3	7	17	24	702.488
#452	LHX9	7	16	23	701.254
#453	POU3F3	7	17	24	621.391
#454	MECOM	7	19	26	614.337
#455	ZNF85	7	18	25	647.351
#456	MYT1L	7	22	29	797.609
#457	TP73	7	11	18	362.027
#458	TBX4	7	12	19	477.664
#459	HNF4G	7	13	20	393.069
#460	PITX1	7	18	25	574.251
#461	ZEB2	7	15	22	444.285
#462	POU1F1	7	18	25	490.705
#463	EPAS1	7	14	21	692.986
#464	SLC26A3	7	17	24	887.549
#465	C12orf28	6	18	24	502.762
#466	TBX3	6	19	25	742.293
#467	C2orf3	6	11	17	219.899
#468	ENO1	6	14	20	367.748
#469	FLI1	6	20	26	525.501
#470	CREBZF	6	17	23	576.042
#471	PITX2	6	19	25	485.652
#472	SCAND2	6	18	24	599.431
#473	ONECUT2	6	19	25	412.095
#474	PLSCR1	6	23	29	482.831
#475	ESX1	6	19	25	491.284
#476	TFAP2B	6	17	23	418.571
#477	RERE	6	9	15	336.656
#478	MKX	6	18	24	481.674
#479	ESRRB	6	20	26	591.795
#480	ZSCAN23	6	13	19	315.501
#481	HOXA13	6	13	19	463.318
#482	LHX1	6	14	20	605.433
#483	POU2F3	6	17	23	375.659
#484	TBX22	6	20	26	597.074
#485	NFE2L2	6	18	24	737.993
#486	TSC22D2	5	17	22	392.349
#487	PAX6	5	15	20	327.46
#488	ZNF396	5	14	19	329.327
#489	PPBPL2	5	16	21	456.96
#490	ZNF41	5	15	20	251.663
#491	TEAD2	5	21	26	636.031
#492	ANKRD30A	5	24	29	757.62
#493	FOXA1	4	17	21	307.778
#494	MEOX2	4	17	21	480.992
#495	TBX20	4	18	22	478.946
#496	ARNTL2	3	22	25	255.696
#497	ZNF157	3	16	19	170.295
#498	ST18	3	19	22	261.198
#499	NCOR1	2	13	15	116.467
#500	NR2E3	2	16	18	193.889