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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TGIF1	46	2	48	125.974
#2	CREB3L2	44	2	46	842.97
#3	HOPX	35	5	40	1195.538
#4	GAS7	32	4	36	787.517
#5	TCF7L2	30	3	33	807.142
#6	NR4A2	28	7	35	704.084
#7	CUX1	28	5	33	1181.104
#8	TCF4	28	6	34	788.044
#9	TBX21	27	8	35	1056.16
#10	CREB5	26	5	31	1357.119
#11	STAT4	25	4	29	496.11
#12	HOXA1	25	10	35	1376.048
#13	MAF	24	9	33	1489.542
#14	LEF1	24	5	29	289.396
#15	MAFB	24	11	35	1030.529
#16	ZSCAN18	24	9	33	1770.082
#17	PHTF1	24	8	32	442.541
#18	KLF3	23	10	33	1381.239
#19	ZEB1	23	8	31	743.18
#20	MYC	23	7	30	242.075
#21	ZNF287	22	8	30	1869.977
#22	MEIS2	22	10	32	1620.666
#23	SMAD3	22	7	29	1445.15
#24	HES1	22	7	29	377.969
#25	AHR	22	13	35	1741.287
#26	FOXP4	21	6	27	1346.633
#27	BCL11B	21	4	25	985.591
#28	PLAG1	21	11	32	2802.595
#29	ZNF165	21	10	31	1166.987
#30	IRF4	21	10	31	924.264
#31	ETS1	21	9	30	1422.623
#32	SEBOX	21	11	32	1377.323
#33	EBF1	20	5	25	154.07
#34	ETV5	20	13	33	1074.977
#35	CREM	20	6	26	642.11
#36	NR4A1	20	5	25	1030.517
#37	PBX4	20	11	31	1993.181
#38	TBX15	20	10	30	907.519
#39	FOSL2	19	9	28	1131.267
#40	SMAD2	19	13	32	1193.266
#41	NR4A3	19	5	24	258.98
#42	TCF25	19	5	24	382.907
#43	EGR3	18	7	25	1015.718
#44	CTBP1	18	10	28	1796.772
#45	BHLHE41	18	10	28	979.033
#46	ZNF117	18	11	29	2178.92
#47	TADA3	18	10	28	1421.39
#48	HSF5	18	9	27	1229.374
#49	MEF2C	18	11	29	1986.21
#50	SIX2	18	7	25	1441.675
#51	SIX3	18	7	25	1687.521
#52	EGR2	18	8	26	1212.959
#53	RXRA	18	11	29	1056.953
#54	CSDA	18	11	29	1865.862
#55	ESR2	18	6	24	314.612
#56	SOX5	18	12	30	924.365
#57	HESX1	18	13	31	1085.587
#58	HOXA5	18	9	27	992.437
#59	POU3F1	18	9	27	1361.692
#60	MXD1	17	15	32	2283.413
#61	TAF4B	17	6	23	188.739
#62	TP63	17	13	30	2173.914
#63	VAX2	17	10	27	1854.357
#64	SOX4	17	11	28	372.569
#65	MYT1	17	10	27	1132.235
#66	MGA	17	14	31	1909.017
#67	KLF10	17	8	25	548.066
#68	MEIS3P1	17	16	33	2552.519
#69	KLF11	17	11	28	877.287
#70	KLF4	17	12	29	1044.095
#71	HOXB2	17	15	32	852.428
#72	GATA3	16	13	29	907.467
#73	HOXB6	16	9	25	2814.148
#74	BHLHE40	16	6	22	421.5
#75	ETS2	16	12	28	1862.98
#76	LHX2	16	11	27	1867.587
#77	HOXA3	16	10	26	1157.94
#78	UHRF1	16	11	27	2258.14
#79	KLF7	16	10	26	955.629
#80	ZNF41	16	9	25	1238.94
#81	FOXO3	16	9	25	1426.106
#82	PRDM2	16	13	29	2181.742
#83	GSC2	16	7	23	1127.109
#84	ZNF148	16	11	27	2043.361
#85	ZNF154	16	12	28	1729.163
#86	ZSCAN10	16	11	27	2238.281
#87	MAFF	16	8	24	691.601
#88	NPAS1	16	11	27	1556.653
#89	ATF5	15	8	23	1442.272
#90	ATOH1	15	9	24	1295.077
#91	SNAI3	15	10	25	2021.314
#92	TFAP2D	15	4	19	581.897
#93	LHX9	15	8	23	1380.559
#94	ZNF155	15	9	24	1474.804
#95	SP3	15	11	26	581.235
#96	GLI3	15	11	26	1084.908
#97	TBX6	15	8	23	1330.333
#98	SIM2	15	14	29	1600.508
#99	MYCN	15	11	26	1918.83
#100	FOXD3	15	10	25	1744.081
#101	KCNH8	15	13	28	1973.932
#102	TRERF1	15	11	26	997.17
#103	VDR	14	10	24	1527.846
#104	HOXB7	14	16	30	1706.41
#105	PBX3	14	15	29	1414.121
#106	FOSB	14	7	21	688.187
#107	TEAD2	14	5	19	154.083
#108	FOXD1	14	11	25	1041.051
#109	GLIS3	14	8	22	1401.127
#110	CREBBP	14	9	23	1507.223
#111	TSHZ3	14	10	24	464.171
#112	ELK3	14	11	25	970.616
#113	HOXC12	14	15	29	1584.821
#114	E2F7	14	10	24	1767.49
#115	E2F2	14	10	24	1457.979
#116	SLC2A4RG	14	9	23	930.178
#117	POU3F4	14	10	24	1075.836
#118	FOXP1	14	10	24	1215.737
#119	MYCL1	14	12	26	1846.923
#120	SOX18	14	10	24	1275.426
#121	ZNF135	14	10	24	1055.454
#122	ZNF3	14	12	26	1585.189
#123	RARA	14	17	31	3138.742
#124	HIF1A	14	9	23	1591.229
#125	GTF2IRD1	13	8	21	724.28
#126	NR6A1	13	11	24	2044.977
#127	IKZF4	13	9	22	1422.29
#128	RUNX2	13	11	24	721.405
#129	KLF16	13	11	24	1997.372
#130	PRDM1	13	9	22	935.533
#131	ARNTL	13	11	24	1221.401
#132	FOXD4	13	11	24	1374.836
#133	AEBP1	13	14	27	1606.768
#134	KLF12	13	11	24	1372.836
#135	TSHZ2	13	14	27	1485.128
#136	SALL1	13	11	24	1174.625
#137	TFE3	13	5	18	623.97
#138	FOS	13	11	24	1368.948
#139	KLF17	13	10	23	1256.776
#140	HOXA9	13	14	27	1765.433
#141	HOXD3	13	12	25	1364.724
#142	TFAP2B	13	8	21	911.976
#143	GATA4	13	8	21	1774.074
#144	MSX1	13	8	21	909.983
#145	ZNF207	13	10	23	1091.15
#146	POU5F2	13	13	26	1439.815
#147	HOXD13	13	11	24	1130.407
#148	TFEC	13	15	28	1121.899
#149	GSX2	12	11	23	1499.079
#150	RBPJL	12	14	26	2232.056
#151	PITX2	12	8	20	789.373
#152	ATF3	12	10	22	728.918
#153	ZBTB38	12	7	19	337.917
#154	MLL	12	16	28	1797.107
#155	WNT5A	12	13	25	1512.126
#156	ZNF85	12	13	25	979.509
#157	NR3C2	12	8	20	1025.002
#158	ELK1	12	12	24	1922.415
#159	TBX3	12	10	22	1347.755
#160	SCML1	12	10	22	667.277
#161	MSRB2	12	6	18	778.442
#162	EN1	12	10	22	1166.669
#163	IRF5	12	9	21	1091.239
#164	RFXAP	12	8	20	822.637
#165	ZFP36L1	12	11	23	1067.141
#166	ZNF80	12	12	24	978.379
#167	CREBZF	12	9	21	1238.881
#168	SNAPC5	12	8	20	814.913
#169	NFE2L3	12	13	25	722.639
#170	KLF1	12	13	25	1346.418
#171	HMGA2	12	11	23	1465.115
#172	MYNN	12	9	21	981.599
#173	NANOG	12	16	28	1235.386
#174	TGIF2LY	12	12	24	1264.757
#175	HLF	12	12	24	1405.316
#176	NR5A2	11	9	20	1070.827
#177	ZSCAN20	11	8	19	832.78
#178	NKX3-2	11	14	25	1565.828
#179	TAF13	11	11	22	737.389
#180	FOXP2	11	10	21	1501.108
#181	NPAT	11	13	24	1334.048
#182	ZIC2	11	9	20	1013.953
#183	MYF6	11	13	24	786.371
#184	TEF	11	14	25	1767.603
#185	PPARA	11	13	24	1282.085
#186	RUNX1T1	11	11	22	1345.493
#187	MSC	11	10	21	1115.671
#188	CSRNP3	11	10	21	927.361
#189	HNF4A	11	11	22	1240.851
#190	OVOL1	11	10	21	849.35
#191	TADA2A	11	9	20	844.511
#192	HNF1A	11	9	20	989.732
#193	AR	11	9	20	936.574
#194	ESRRB	11	11	22	1177.907
#195	HES6	11	13	24	1172.426
#196	SMAD1	11	12	23	1586.73
#197	NFIC	11	13	24	2350.852
#198	HOXD4	11	12	23	1448.254
#199	TBX20	11	12	23	1061.825
#200	SNAI2	11	12	23	1100.089
#201	ESRRG	11	11	22	1137.71
#202	FOXJ1	11	12	23	1126.72
#203	SATB1	11	13	24	1318.551
#204	SCAND2	11	9	20	840.492
#205	MEIS3	11	11	22	1547.529
#206	ZFP36L2	11	15	26	1144.393
#207	PPARG	11	7	18	649.517
#208	TSC22D1	11	13	24	1671.039
#209	HNRNPAB	11	9	20	1282.54
#210	RAX2	11	8	19	1262.206
#211	ZHX3	11	13	24	646.411
#212	C12orf28	11	11	22	1297.247
#213	NANOGNB	11	12	23	1868.82
#214	ARNT2	11	10	21	840.751
#215	DLX1	11	8	19	645.212
#216	NOBOX	11	11	22	1449.259
#217	GLIS2	10	10	20	917.208
#218	HMG20B	10	14	24	995.965
#219	SOX9	10	11	21	909.138
#220	HMGB2	10	9	19	801.504
#221	OTX2	10	9	19	674.53
#222	MYBL2	10	15	25	813.769
#223	LMO4	10	8	18	562.184
#224	MESP1	10	7	17	736.449
#225	MSX2	10	11	21	879.39
#226	ELF5	10	9	19	1114.634
#227	EGR1	10	7	17	249.089
#228	SOX11	10	16	26	727.608
#229	PEG3	10	9	19	616.154
#230	FOXA2	10	9	19	820.13
#231	SOX6	10	11	21	1044.594
#232	ZKSCAN3	10	15	25	1139.356
#233	RCOR1	10	12	22	838.446
#234	HOXA6	10	9	19	1321.404
#235	AFF4	10	6	16	471.791
#236	FOXR2	10	9	19	505.259
#237	TFAP2C	10	7	17	644.923
#238	SOX7	10	16	26	955.609
#239	PPARD	10	12	22	1479.509
#240	SOX2	10	14	24	1284.056
#241	FOXM1	10	10	20	1084.918
#242	SOX8	10	13	23	724.085
#243	NFKB2	10	14	24	1372.93
#244	ZNF397	10	8	18	780.423
#245	HOXA2	10	9	19	894.684
#246	NR2F1	10	10	20	1085.867
#247	FOXP3	10	11	21	866.22
#248	HDX	10	14	24	1364.066
#249	MITF	10	10	20	1124.063
#250	BLZF1	10	8	18	1273.649
#251	TAL1	10	11	21	1014.729
#252	ZNF90	10	8	18	700.868
#253	KLF2	10	10	20	1366.063
#254	PCGF2	10	11	21	1311.797
#255	HOXD1	10	12	22	1108.8
#256	GATAD1	10	10	20	1113.178
#257	PAX3	10	10	20	571.145
#258	TRPS1	10	8	18	603.777
#259	PPBPL2	10	9	19	643.343
#260	ZNF71	10	12	22	1027.369
#261	ISX	10	10	20	994.819
#262	EHF	10	12	22	1479.796
#263	RELA	10	11	21	1090.361
#264	FOXA3	10	16	26	2163.11
#265	ONECUT1	10	13	23	1346.956
#266	SOX17	10	10	20	508.878
#267	PTH	10	10	20	1133.601
#268	ZSCAN2	10	15	25	1090.733
#269	MBD1	10	12	22	1114.558
#270	TCF7L1	10	13	23	1393.284
#271	ZNF81	10	10	20	551.385
#272	ZNF444	9	11	20	1037.061
#273	SPIC	9	14	23	1264.493
#274	E2F8	9	9	18	645.111
#275	PLSCR1	9	10	19	1161.762
#276	ZNF483	9	12	21	1052.06
#277	ZNF132	9	13	22	1250.375
#278	MYT1L	9	13	22	1601.779
#279	ZFP42	9	9	18	866.67
#280	LMX1A	9	10	19	899.972
#281	ZFPM2	9	13	22	1191.037
#282	NR2F6	9	18	27	1622.535
#283	FOXE1	9	9	18	562.225
#284	PAX6	9	13	22	1161.059
#285	ST18	9	16	25	1615.262
#286	TBX2	9	11	20	593.148
#287	HOXB3	9	11	20	740.522
#288	ATF7	9	11	20	967.539
#289	SIX1	9	9	18	683.411
#290	EN2	9	11	20	870.758
#291	FOSL1	9	14	23	908.812
#292	ONECUT2	9	7	16	820.386
#293	FOXL2	9	10	19	651.614
#294	NFE2	9	14	23	1257.251
#295	TLX3	9	15	24	1851.439
#296	PAX5	9	10	19	950.102
#297	OTX1	9	17	26	1732.808
#298	ZKSCAN2	9	12	21	1075.683
#299	SIX5	9	14	23	972.728
#300	LZTS1	9	14	23	1318.515
#301	MIXL1	9	12	21	872.21
#302	DMRT1	9	13	22	1145.121
#303	ZIC3	9	11	20	992.368
#304	ZFHX2	9	12	21	1064.702
#305	ZIC5	9	11	20	1014.187
#306	ALX3	9	13	22	971.828
#307	TSC22D2	9	10	19	1217.103
#308	LHX1	9	12	21	1376.253
#309	FOXN4	9	11	20	769.389
#310	POU4F2	9	10	19	1251.672
#311	HIC1	9	14	23	1259.164
#312	NKX2-8	9	7	16	760.658
#313	HOXA4	9	10	19	873.058
#314	GATA5	9	10	19	520.464
#315	TRIM29	9	7	16	770.457
#316	NKX2-1	9	8	17	851.486
#317	DMRT2	8	12	20	1003.275
#318	NFATC2	8	15	23	1136.15
#319	PAX7	8	16	24	1061.307
#320	IRX1	8	12	20	1354.057
#321	RARB	8	14	22	908.154
#322	HIF3A	8	17	25	1271.809
#323	SOX30	8	14	22	927.675
#324	STAT5B	8	11	19	798.36
#325	ARNT	8	10	18	999.214
#326	GCM1	8	11	19	1067.584
#327	RORA	8	11	19	1079.889
#328	ASCL1	8	16	24	1207.147
#329	TWIST2	8	13	21	860.685
#330	NFYA	8	13	21	1087.02
#331	FOXL1	8	12	20	1014.638
#332	NKX2-5	8	11	19	839.037
#333	ZIC1	8	13	21	806.782
#334	ESR1	8	14	22	1002.996
#335	PRRX1	8	11	19	971.108
#336	MYF5	8	13	21	946.434
#337	TBX1	8	13	21	870.581
#338	NEUROG1	8	10	18	893.462
#339	NFIA	8	10	18	687.259
#340	SIX4	8	10	18	808.616
#341	HOXC9	8	12	20	777.503
#342	ZNF496	8	9	17	467.862
#343	NKX6-2	8	9	17	1283.993
#344	SMAD9	8	11	19	718.891
#345	NR2F2	8	11	19	789.114
#346	HOXA10	8	20	28	937.627
#347	POU3F3	8	13	21	1698.651
#348	FOXH1	8	7	15	653.91
#349	ZSCAN23	8	12	20	946.043
#350	L3MBTL4	8	14	22	1609.621
#351	PKNOX2	8	8	16	511.418
#352	NEUROD1	8	15	23	1304.875
#353	ESX1	8	10	18	918.824
#354	POU2F3	8	10	18	916.846
#355	ZNF93	8	6	14	379.267
#356	C2orf3	8	13	21	896.218
#357	ANKRD30A	8	13	21	1158.146
#358	BARX1	8	10	18	1123.924
#359	TBX5	8	13	21	699.143
#360	ETV7	8	15	23	1034.443
#361	ZNF396	8	10	18	700.706
#362	FOXF1	8	12	20	1102.824
#363	HOXA7	7	10	17	1596.107
#364	TBX22	7	6	13	364.557
#365	HNF4G	7	11	18	533.988
#366	LASS5	7	11	18	1028.586
#367	NFIB	7	13	20	729.53
#368	FOXN3	7	12	19	835.531
#369	ZSCAN1	7	11	18	499.249
#370	LASS6	7	12	19	969.491
#371	EPAS1	7	12	19	463.342
#372	HOXC10	7	11	18	689.834
#373	HOXB9	7	11	18	815.567
#374	SOX13	7	10	17	618.501
#375	CUX2	7	9	16	725.836
#376	GSX1	7	11	18	698.794
#377	POU2F1	7	13	20	743.271
#378	EVX1	7	11	18	634.648
#379	VSX1	7	11	18	753.57
#380	POU1F1	7	10	17	765.915
#381	TCF7	7	12	19	366.702
#382	LHX6	7	10	17	813.308
#383	CEBPD	7	14	21	1190.397
#384	SATB2	7	13	20	816.395
#385	TP73	7	15	22	537.73
#386	RARG	7	14	21	764.034
#387	VTN	7	11	18	652.259
#388	RCAN1	7	13	20	892.653
#389	SCAND3	7	15	22	774.75
#390	PAX8	7	13	20	1090.54
#391	NR1I2	7	8	15	549.71
#392	CCRN4L	7	14	21	437.014
#393	POU6F2	7	9	16	600.492
#394	TULP4	7	12	19	680.989
#395	GLI2	7	10	17	605.397
#396	NEUROD2	7	13	20	883.429
#397	POU4F3	7	9	16	517.585
#398	ERG	7	11	18	548.817
#399	NOTCH1	7	15	22	1198.669
#400	TFAP2A	7	10	17	799.558
#401	VENTX	7	13	20	831.053
#402	RXRG	7	15	22	853.191
#403	IRF6	7	7	14	440.141
#404	HOMEZ	6	10	16	343.817
#405	NCOR1	6	14	20	1045.265
#406	HCFC1	6	11	17	826.745
#407	HIRA	6	11	17	555.205
#408	NFATC4	6	13	19	899.163
#409	IRX3	6	12	18	796.604
#410	SMAD6	6	10	16	550.824
#411	ZNF157	6	13	19	826.178
#412	REST	6	13	19	515.632
#413	FLI1	6	13	19	1364.389
#414	LHX8	6	11	17	704.139
#415	NFIX	6	11	17	578.349
#416	GRHL2	6	15	21	1163.076
#417	NR2E1	6	8	14	441.274
#418	HOXD10	6	12	18	705.052
#419	ISL1	6	12	18	600.486
#420	IRX4	6	12	18	730.889
#421	HOXB8	6	10	16	605.502
#422	NFE2L2	6	12	18	745.544
#423	MECOM	6	16	22	1410.776
#424	BNC1	6	10	16	564.249
#425	HAND2	6	5	11	289.119
#426	SLC26A3	6	8	14	345.671
#427	OLIG2	6	18	24	1509.087
#428	DMBX1	6	15	21	835.082
#429	IRX5	6	14	20	830.243
#430	DLX6	6	15	21	663.359
#431	BCL3	6	11	17	385.071
#432	GRHL3	6	8	14	447.558
#433	PROX1	6	15	21	895.499
#434	TFCP2L1	6	11	17	813.283
#435	BCL6	6	9	15	253.132
#436	TWIST1	6	11	17	703.696
#437	ZNF174	6	10	16	680.405
#438	EGR4	6	13	19	1095.545
#439	ELF3	6	10	16	505.645
#440	C11orf9	6	12	18	526.703
#441	CREB3L3	6	11	17	734.202
#442	ZNF131	5	16	21	866.117
#443	FOXI1	5	12	17	753.288
#444	GATA2	5	10	15	611.658
#445	PHOX2B	5	15	20	751.405
#446	ZFP37	5	15	20	1687.645
#447	FOXD2	5	15	20	817.078
#448	GATAD2A	5	14	19	736.145
#449	KLF9	5	12	17	757.606
#450	ZFHX4	5	11	16	576.345
#451	ELK4	5	9	14	890.186
#452	NR2E3	5	11	16	710.126
#453	SOX1	5	11	16	568.19
#454	MEIS1	5	13	18	794.577
#455	RUNX1	5	15	20	794.749
#456	NPAS2	5	11	16	611.607
#457	FOXA1	5	11	16	580.184
#458	ISL2	5	13	18	481.662
#459	GATA6	5	13	18	694.745
#460	BRD8	5	16	21	737.438
#461	RORB	5	10	15	421.241
#462	ZSCAN12	5	10	15	394.724
#463	PGR	5	11	16	530.162
#464	TFDP3	5	10	15	465.354
#465	SIM1	5	6	11	290.229
#466	FOXC1	5	15	20	787.41
#467	ETV1	5	18	23	594.123
#468	USF1	5	11	16	608.57
#469	HOXD11	5	15	20	899.165
#470	PKNOX1	5	14	19	553.167
#471	ARNTL2	5	12	17	952.997
#472	DLX2	4	15	19	763.864
#473	PAX4	4	15	19	482.44
#474	MEOX2	4	9	13	750.121
#475	ZNF215	4	15	19	759.888
#476	TCF20	4	16	20	651.598
#477	ETV3	4	8	12	315.866
#478	ZFHX3	4	15	19	620.603
#479	RERE	4	7	11	721.791
#480	TEAD1	4	9	13	310.993
#481	ZNF167	4	13	17	771.916
#482	ZEB2	4	14	18	966.355
#483	TEAD3	4	13	17	478.387
#484	ASCL2	4	14	18	483.18
#485	MKX	4	11	15	234.462
#486	NR0B1	4	14	18	530.951
#487	ZSCAN4	4	10	14	898.217
#488	ARX	4	13	17	736.738
#489	TBR1	3	15	18	339.756
#490	HEY2	3	16	19	506.046
#491	POU3F2	3	16	19	455.238
#492	NKX2-3	3	16	19	468.121
#493	POU4F1	3	9	12	284.038
#494	NR1I3	2	11	13	299.534
#495	TCF21	2	14	16	331.927
#496	THRB	2	14	16	191.392
#497	ETV2	2	10	12	235.682
#498	NR1H4	2	9	11	254.914
#499	NKX6-1	2	12	14	205.508
#500	PBX1	1	10	11	136.751