Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	AFF4	39	7	46	5050.183
#2	RUNX1T1	31	6	37	2428.604
#3	CEBPB	27	2	29	47.559
#4	SREBF1	27	7	34	1977.068
#5	SOX18	25	11	36	1977.663
#6	SPIB	25	8	33	2424.157
#7	HMX1	24	8	32	1219.175
#8	CEBPD	23	2	25	39.247
#9	CSDA	23	9	32	618.932
#10	HAND1	23	4	27	417.408
#11	FOXO3	23	7	30	1663.365
#12	UHRF1	23	5	28	449.797
#13	RORA	22	14	36	3030.503
#14	ELF1	22	12	34	2379.183
#15	HES6	22	9	31	1230.601
#16	VAX2	22	10	32	2197.68
#17	ZEB1	22	11	33	1570.634
#18	JUNB	22	0	22	0
#19	TGIF2	22	10	32	2601.83
#20	NR4A2	22	5	27	137.425
#21	SOX6	21	8	29	1338.362
#22	LASS5	21	7	28	1246.609
#23	CSRNP1	21	1	22	19.256
#24	MLXIPL	21	7	28	1683.527
#25	SMAD5	20	8	28	1403.264
#26	E2F1	20	6	26	795.546
#27	FOSL2	20	5	25	1399.374
#28	FOXP1	20	12	32	3156.967
#29	MYCN	20	15	35	2858.268
#30	NR4A1	20	5	25	92.333
#31	MAFF	20	6	26	185.604
#32	HOXA3	20	11	31	1414.364
#33	GTF2H2	19	6	25	2004.778
#34	FOXM1	19	2	21	109.307
#35	LASS6	19	5	24	969.931
#36	PRRX1	19	8	27	676.44
#37	IRX5	19	11	30	1472.105
#38	GATA4	19	7	26	1876.278
#39	RXRA	19	6	25	1049.103
#40	VENTX	19	11	30	2830.196
#41	FOXD3	19	6	25	734.444
#42	ETV5	19	8	27	817.071
#43	TADA2A	19	8	27	1541.176
#44	NR4A3	19	5	24	656.271
#45	DLX6	18	9	27	846.161
#46	SOX9	18	15	33	2470.773
#47	ZNF444	18	8	26	1701.516
#48	TFEC	18	10	28	2120.57
#49	ZFP36L2	18	8	26	1452.123
#50	MYBL2	18	8	26	1304.223
#51	FOXD1	18	13	31	2088.654
#52	FOXC1	18	9	27	420.503
#53	ATF2	18	8	26	1444.168
#54	HOXA5	18	7	25	326.964
#55	CREB3L1	17	7	24	327.064
#56	ZNF41	17	10	27	2345.5
#57	TWIST1	17	10	27	1720.73
#58	IRX3	17	6	23	1434.321
#59	NFAT5	17	7	24	2305.477
#60	MGA	17	11	28	1950.066
#61	HAND2	17	9	26	1720.783
#62	E2F7	17	3	20	259.196
#63	GAS7	17	6	23	1727.219
#64	LZTS1	17	10	27	1740.731
#65	HOXA7	17	8	25	563.706
#66	PKNOX1	16	8	24	1881.656
#67	ETS1	16	8	24	2269.52
#68	KLF5	16	7	23	1382.904
#69	RXRB	16	9	25	1527.12
#70	ZNF238	16	14	30	904.798
#71	TBX3	16	10	26	1672.473
#72	FOS	16	4	20	73.211
#73	E2F8	16	6	22	402.821
#74	EGR3	16	7	23	151.273
#75	FOXQ1	16	8	24	1838.026
#76	TEAD4	16	13	29	1489.083
#77	HOXB7	16	8	24	997.583
#78	SOX17	16	5	21	652.325
#79	SCRT1	16	10	26	2489.105
#80	HEY2	16	11	27	1368.902
#81	TBX1	16	13	29	2419.984
#82	ZRANB2	16	7	23	1096.92
#83	ZNF75D	15	5	20	830.093
#84	TSHZ2	15	6	21	1293.596
#85	TFAP2A	15	5	20	373.63
#86	HOXC10	15	7	22	823.983
#87	SIX5	15	14	29	1049.02
#88	EMX1	15	9	24	1169.221
#89	GRHL2	15	12	27	2736.384
#90	VTN	15	12	27	2169.77
#91	GATA1	15	7	22	1617.929
#92	FUBP1	15	10	25	1145.029
#93	KLF4	15	7	22	167.554
#94	TGIF1	15	10	25	723.43
#95	TBX15	15	10	25	1241.8
#96	HOXD11	15	6	21	761.736
#97	EGR2	15	8	23	229.64
#98	FOXR2	15	8	23	1613.763
#99	EGR1	14	7	21	134.749
#100	ZNF93	14	11	25	1217.404
#101	ZFHX3	14	14	28	1743.047
#102	STAT6	14	15	29	1775.135
#103	HOXC5	14	10	24	2405.803
#104	TLX2	14	7	21	893.673
#105	GRHL3	14	15	29	2755.653
#106	MMP14	14	11	25	866.814
#107	RUNX3	14	6	20	1511.943
#108	ZNF85	14	12	26	1155.455
#109	MYT1L	14	8	22	898.157
#110	ZBTB25	14	11	25	1650.627
#111	SOX10	14	3	17	661.386
#112	RB1	14	9	23	700.255
#113	CITED1	14	10	24	1729.721
#114	MEIS2	14	11	25	1277.769
#115	TULP4	14	13	27	1598.538
#116	FOXP3	14	12	26	1803.68
#117	SIX2	14	6	20	1139.194
#118	FOSB	14	8	22	132.968
#119	PTTG1	14	3	17	182.254
#120	ZFP36L1	14	10	24	680.959
#121	TBX5	14	9	23	1193.917
#122	MAFG	14	9	23	1273.124
#123	FOXP2	14	12	26	2172.668
#124	ZNF287	13	10	23	1135.745
#125	FEV	13	13	26	991.002
#126	HOXD13	13	9	22	916.956
#127	MLL	13	8	21	1066.057
#128	NFIX	13	9	22	1035.258
#129	ENO1	13	11	24	1059.245
#130	FOXL1	13	7	20	848.455
#131	KLF2	13	10	23	1754.597
#132	PURB	13	12	25	1502.336
#133	CREBZF	13	13	26	2218.766
#134	ERF	13	10	23	1330.318
#135	ZSCAN10	13	10	23	1624.346
#136	AFF1	13	9	22	1749.593
#137	ZNF157	13	15	28	2598.134
#138	HMGB2	13	9	22	1979.071
#139	ZFHX4	13	10	23	1251.813
#140	GATA5	13	8	21	698.284
#141	ZHX3	13	10	23	994.999
#142	ZBTB38	13	11	24	725.064
#143	TBX10	13	9	22	1899.949
#144	MEIS1	13	12	25	2274.285
#145	FOXJ2	12	9	21	1231.159
#146	NANOG	12	10	22	880.876
#147	CREB5	12	12	24	1224.535
#148	FOXE3	12	8	20	875.479
#149	ZFP42	12	7	19	816.878
#150	ZNF215	12	14	26	1913.102
#151	SOX8	12	12	24	946.974
#152	MSX2	12	9	21	971.898
#153	IRF4	12	10	22	1235.003
#154	TFDP1	12	10	22	2567.747
#155	PPARG	12	7	19	443.639
#156	BTG2	12	6	18	673.116
#157	RORB	12	9	21	750.776
#158	TEAD1	12	6	18	717.551
#159	MESP2	12	11	23	1658.969
#160	ELF3	12	11	23	1452.344
#161	VDR	12	11	23	1686.969
#162	KLF9	12	11	23	1319.892
#163	ATF5	12	17	29	2902.57
#164	ATF1	12	7	19	1269.04
#165	ZNF174	12	8	20	1438.798
#166	ELF4	12	14	26	2230.218
#167	PKNOX2	12	13	25	1889.676
#168	SNAI3	12	9	21	1446.536
#169	TCF3	12	11	23	1544.658
#170	ZSCAN2	12	9	21	1602.248
#171	YY1	11	12	23	1051.458
#172	SOX13	11	10	21	1833.079
#173	SEBOX	11	17	28	1880.06
#174	NFYA	11	9	20	755.616
#175	HOXC9	11	13	24	580.234
#176	NR2F1	11	16	27	1694.01
#177	ETV1	11	14	25	1476.217
#178	ZIC2	11	12	23	1235.392
#179	E2F2	11	6	17	952.078
#180	NFATC1	11	6	17	1243.527
#181	HOXD3	11	15	26	1164.778
#182	HOXD10	11	13	24	1798.129
#183	HOXD9	11	15	26	2288.787
#184	FOXA3	11	8	19	811.563
#185	TCF7L2	11	8	19	578.95
#186	POU3F2	11	10	21	1642.673
#187	PBX3	11	13	24	3141.85
#188	MEF2D	11	7	18	549.631
#189	ZNF71	11	9	20	760.906
#190	ZIC3	11	13	24	2255.758
#191	MIXL1	11	8	19	1242.879
#192	NR3C2	11	11	22	723.712
#193	NR0B1	11	6	17	936.476
#194	SIM2	11	8	19	825.651
#195	POU6F1	11	10	21	1645.172
#196	MNT	11	9	20	1076.161
#197	KLF17	11	14	25	2563.384
#198	HNF1A	11	10	21	1365.066
#199	HES5	10	5	15	711.436
#200	HOXA10	10	10	20	1067.432
#201	KLF16	10	12	22	1276.309
#202	ARX	10	14	24	2151.768
#203	BACH1	10	6	16	282.743
#204	NFIC	10	8	18	996.497
#205	KLF12	10	11	21	1486.614
#206	POU3F1	10	10	20	508.131
#207	PPARD	10	12	22	1428.652
#208	NKX6-2	10	10	20	1559.741
#209	SIX3	10	10	20	1061.665
#210	PROX1	10	14	24	1310.534
#211	ZNF80	10	6	16	800.639
#212	PRRX2	10	12	22	832.057
#213	PEG3	10	9	19	1013.339
#214	SPI1	10	7	17	628.485
#215	CUX2	10	10	20	867.049
#216	NANOGNB	10	13	23	1343.177
#217	SLC26A3	10	16	26	2207.052
#218	ZSCAN20	10	10	20	1874.825
#219	NKX2-8	10	6	16	631.19
#220	NKX2-5	10	11	21	2598.93
#221	GBX2	10	12	22	2178.205
#222	SP4	10	11	21	519.367
#223	ZNF446	10	8	18	609.713
#224	ONECUT2	10	7	17	966.255
#225	ATF3	10	12	22	1150.51
#226	SMAD6	10	9	19	979.071
#227	C12orf28	10	7	17	1165.448
#228	PAX4	10	10	20	1017.628
#229	THRB	9	9	18	734.91
#230	TSC22D1	9	9	18	894.277
#231	MZF1	9	7	16	875.097
#232	FLI1	9	13	22	1528.819
#233	TADA3	9	10	19	1480.519
#234	SATB2	9	8	17	784.607
#235	GLIS3	9	8	17	266.106
#236	SIX4	9	12	21	468.785
#237	ELK4	9	11	20	1356.002
#238	CDKN2A	9	10	19	1233.908
#239	NEUROD2	9	9	18	956.395
#240	NR5A1	9	15	24	1635.88
#241	ELF5	9	9	18	746.027
#242	BHLHE40	9	8	17	1104.16
#243	FOXP4	9	10	19	1090.646
#244	HCFC1	9	16	25	1321.209
#245	ISX	9	7	16	1111.28
#246	TEAD2	9	13	22	1134.709
#247	FOXJ1	9	6	15	1080.142
#248	MNX1	9	13	22	1037.852
#249	RARA	9	11	20	1142.628
#250	NRL	9	9	18	661.54
#251	ZBTB17	9	10	19	841.815
#252	ALX1	9	13	22	990.97
#253	RFX3	9	8	17	606.944
#254	FOXN4	9	11	20	1090.883
#255	SOX15	9	11	20	1032.255
#256	TBR1	9	14	23	2219.651
#257	TP63	9	14	23	1262.192
#258	EBF1	9	11	20	1113.882
#259	MYF5	9	10	19	1007.19
#260	TFAP2D	9	11	20	1306.973
#261	NPAT	9	10	19	1682.215
#262	WT1	9	11	20	1115.014
#263	TWIST2	9	14	23	1075.496
#264	NR1I2	9	11	20	691.887
#265	PDX1	9	10	19	1173.44
#266	BCL6	9	10	19	692.597
#267	OTX1	9	11	20	1356.561
#268	PTH	9	11	20	872.801
#269	EHF	9	8	17	1036.62
#270	MESP1	9	12	21	1453.112
#271	MEOX2	9	9	18	1194.935
#272	NKX2-1	9	10	19	1282.901
#273	L3MBTL4	9	13	22	1979.321
#274	ETV6	9	4	13	406.667
#275	RAX2	9	11	20	1113.627
#276	SOX2	9	9	18	566.039
#277	FOXL2	9	13	22	909.899
#278	EPAS1	9	10	19	1063.387
#279	SIX1	8	8	16	323.125
#280	NR1H4	8	9	17	657.377
#281	NEUROD1	8	12	20	1683.977
#282	SOX5	8	7	15	694.358
#283	FOXD2	8	13	21	990.724
#284	TFAP2C	8	9	17	845.188
#285	MAX	8	11	19	836.204
#286	ZNF483	8	10	18	884.026
#287	TBX2	8	11	19	634.302
#288	TCF15	8	17	25	1333.434
#289	AHCTF1	8	11	19	863.081
#290	GSX1	8	12	20	1909.204
#291	TBX20	8	9	17	548.206
#292	RUNX2	8	9	17	668.303
#293	ELK3	8	10	18	724.887
#294	MYCL1	8	10	18	1036.12
#295	REST	8	8	16	600.263
#296	ARNT	8	9	17	1061.975
#297	SCAND2	8	5	13	431.188
#298	OLIG2	8	8	16	1395.532
#299	TFCP2L1	8	14	22	1134.485
#300	NKX6-1	8	11	19	641
#301	HOPX	8	13	21	1040.779
#302	TFAP4	8	10	18	554.11
#303	HOXA4	8	10	18	650.238
#304	RERE	8	16	24	2034.143
#305	GATA6	8	8	16	519.626
#306	TFAP2B	8	5	13	334.705
#307	DLX3	8	8	16	825.256
#308	ZNF24	8	15	23	2181.699
#309	NOBOX	8	13	21	1221.513
#310	HIF3A	8	17	25	1722.863
#311	ZNF81	8	7	15	1237.907
#312	SNAPC5	8	11	19	901.484
#313	ZNF367	8	7	15	206.11
#314	HOXB6	8	10	18	2032.46
#315	PAX3	8	11	19	1377.614
#316	HES1	8	10	18	882.123
#317	BCL3	7	9	16	1003.463
#318	NPAS2	7	11	18	919.683
#319	GLI2	7	16	23	1959.336
#320	NR6A1	7	10	17	748.758
#321	NFATC4	7	10	17	767.069
#322	HOXC12	7	13	20	1122.583
#323	LEF1	7	10	17	882.745
#324	FOSL1	7	8	15	242.032
#325	RCAN1	7	10	17	558.343
#326	ZNF397	7	9	16	818.095
#327	PCGF2	7	12	19	757.371
#328	ZEB2	7	9	16	851.087
#329	LMO4	7	10	17	1210.742
#330	ZIC5	7	10	17	1285.518
#331	POU1F1	7	9	16	770.714
#332	ATF6B	7	9	16	722.105
#333	BHLHE41	7	16	23	1801.297
#334	ESX1	7	10	17	1725.197
#335	NPAS1	7	11	18	1331.261
#336	ESR1	7	8	15	566.81
#337	IRF6	7	12	19	761.638
#338	TGIF2LY	7	11	18	1058.499
#339	GCM1	7	7	14	683.326
#340	SALL1	7	11	18	1521.047
#341	TSC22D2	7	13	20	1377.588
#342	NR1I3	7	9	16	642.942
#343	TAF13	7	10	17	648.435
#344	RXRG	7	13	20	887.505
#345	IRX1	7	8	15	1226.954
#346	ZNF117	7	14	21	970.775
#347	TCF21	7	13	20	971.742
#348	RARB	7	9	16	652.862
#349	NFIA	7	11	18	553.542
#350	NEUROG1	7	11	18	1894.466
#351	MLX	7	8	15	688.772
#352	ASCL1	7	15	22	1277.954
#353	LHX3	7	13	20	1499.344
#354	BNC1	7	9	16	728.124
#355	TP73	7	6	13	329.813
#356	TRIM29	7	7	14	606.855
#357	ATOH1	6	9	15	533.788
#358	TAL1	6	11	17	740.19
#359	PRDM2	6	11	17	704.986
#360	HOXB1	6	12	18	687.49
#361	NFIB	6	15	21	949.141
#362	POU5F2	6	8	14	769.459
#363	IRX2	6	10	16	809.885
#364	ATF7	6	12	18	633.953
#365	ELK1	6	9	15	724.31
#366	TFE3	6	14	20	571.303
#367	FOXD4	6	11	17	1146.148
#368	ZSCAN4	6	16	22	1074.137
#369	MAFK	6	11	17	541.967
#370	PAX5	6	7	13	401.891
#371	PITX2	6	11	17	874.795
#372	HOXA9	6	11	17	510.528
#373	MXD1	6	10	16	588.577
#374	NCOR1	6	10	16	487.061
#375	TSC22D3	6	10	16	931.214
#376	PGR	6	13	19	2005.272
#377	SOX30	6	9	15	948.655
#378	BRD8	6	12	18	1239.661
#379	SUPT6H	6	15	21	912.026
#380	SOX21	6	10	16	1016.645
#381	RARG	6	12	18	1534.24
#382	LHX8	6	10	16	701.104
#383	WNT5A	6	12	18	1800.283
#384	ZNF496	6	10	16	693.566
#385	THRA	6	12	18	1234.183
#386	HOXA11	6	6	12	875.151
#387	KDM5B	6	11	17	1190.21
#388	CBL	6	10	16	550.37
#389	ZNF154	6	8	14	517.5
#390	TBX6	6	8	14	435.548
#391	ZNF207	6	10	16	1167.555
#392	ARNTL2	6	12	18	650.605
#393	FOXN3	6	11	17	746.883
#394	FOXH1	6	11	17	1085.841
#395	BARX1	5	9	14	803.187
#396	DLX1	5	15	20	882.186
#397	CREBBP	5	7	12	449.324
#398	FOXA1	5	6	11	221.648
#399	ST18	5	13	18	684.954
#400	ONECUT1	5	14	19	950.206
#401	FOXO1	5	10	15	480.419
#402	DMRT2	5	9	14	702.026
#403	SP140	5	11	16	882.203
#404	ESR2	5	10	15	344.969
#405	BCL11B	5	13	18	877.723
#406	EN2	5	12	17	623.403
#407	HIC1	5	14	19	938.556
#408	ZNF131	5	8	13	495.396
#409	HNRNPAB	5	8	13	516.066
#410	NR5A2	5	16	21	893.718
#411	BLZF1	5	10	15	1571.417
#412	NFE2L2	5	13	18	1069.973
#413	NR2E3	5	9	14	799.009
#414	HOXA2	5	9	14	756.845
#415	SPDEF	5	9	14	526.547
#416	PAX8	5	11	16	654.423
#417	ZNF92	5	13	18	530.685
#418	C11orf9	5	11	16	448.896
#419	SOX1	5	12	17	781.882
#420	GSX2	5	14	19	1765.626
#421	HOXC11	5	7	12	367.113
#422	PAX7	5	13	18	772.492
#423	ETV4	5	15	20	1050.673
#424	ZIC1	5	13	18	1036.363
#425	HOXA1	5	8	13	329.439
#426	PAX6	5	9	14	552.539
#427	SIN3A	5	13	18	867.11
#428	ZSCAN23	4	8	12	396.947
#429	SIX6	4	14	18	720.941
#430	TEF	4	8	12	277.019
#431	MYF6	4	16	20	1048.239
#432	FOXK1	4	8	12	779.975
#433	SIM1	4	9	13	832.095
#434	POU3F3	4	13	17	804.804
#435	MITF	4	9	13	517.691
#436	SPIC	4	8	12	227.672
#437	FOXG1	4	7	11	322.785
#438	JUND	4	9	13	596.624
#439	SLC2A4RG	4	10	14	333.839
#440	MTA2	4	7	11	344.817
#441	NFATC2	4	12	16	544.822
#442	SMAD9	4	10	14	488.205
#443	ZNF396	4	14	18	650.312
#444	FOXE1	4	16	20	760.762
#445	TFDP3	4	9	13	603.713
#446	HNF4A	4	16	20	682.984
#447	LMX1A	4	13	17	635.879
#448	LHX1	4	14	18	921.388
#449	POU2F3	4	11	15	570.741
#450	GLI3	4	16	20	980.456
#451	ESRRB	4	12	16	670.068
#452	FOXC2	4	13	17	926.139
#453	NFE2	4	14	18	523.429
#454	VSX1	4	15	19	962.679
#455	ERG	4	12	16	396.602
#456	NFYC	4	13	17	1148.764
#457	PURA	4	12	16	489.378
#458	TRERF1	4	9	13	449.69
#459	PPARA	4	7	11	592.944
#460	ZSCAN18	4	11	15	438.438
#461	STRN3	4	11	15	629.414
#462	ZSCAN1	4	10	14	643.932
#463	TLX3	3	15	18	453.311
#464	POU4F2	3	13	16	983.988
#465	TCF20	3	10	13	323.836
#466	POU4F1	3	12	15	499.992
#467	CREB3L3	3	14	17	466.375
#468	ASCL2	3	10	13	488.478
#469	ZSCAN12	3	10	13	334.687
#470	DLX2	3	13	16	274.418
#471	CLOCK	3	11	14	507.883
#472	KLF1	3	15	18	363.114
#473	MAF	3	7	10	163.649
#474	IKZF3	3	6	9	498.475
#475	HMGA2	3	12	15	406.407
#476	NFKB2	3	12	15	645.977
#477	CTBP1	3	8	11	323.372
#478	LHX2	3	12	15	521.243
#479	RORC	3	14	17	396.517
#480	HIRA	3	7	10	353.876
#481	RBPJL	3	6	9	332.617
#482	RELA	3	14	17	534.19
#483	MECOM	3	11	14	433.039
#484	IKZF1	3	8	11	583.833
#485	CSRNP3	3	10	13	335.76
#486	DMRT1	2	8	10	216.039
#487	HR	2	10	12	164.798
#488	GSC2	2	10	12	355.486
#489	HSF5	2	14	16	364.18
#490	ZNF219	2	14	16	204.976
#491	CREM	2	14	16	330.345
#492	HOXB8	2	15	17	623.259
#493	DLX4	2	10	12	419.349
#494	EGR4	2	14	16	288.329
#495	HOXD1	1	13	14	151.129
#496	HNF4G	1	14	15	291.41
#497	HESX1	1	14	15	173.418
#498	HMG20B	1	10	11	100.365
#499	RUNX1	1	11	12	83.007
#500	LHX9	0	9	9	0