Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SALL1	58	6	64	441.888
#2	MLL	55	5	60	1045.338
#3	HLF	54	3	57	105.655
#4	MLX	51	6	57	1074.214
#5	PFDN1	50	9	59	1010.092
#6	RBPJ	50	11	61	2595.448
#7	NR1H4	48	6	54	2318.709
#8	TFAP4	47	5	52	623.441
#9	GTF2H3	45	7	52	1170.256
#10	TCF20	44	5	49	312.583
#11	CUX1	43	10	53	790.257
#12	MLLT10	43	8	51	597.917
#13	SOX4	41	8	49	688.054
#14	NR2F2	41	12	53	1912.257
#15	PA2G4	41	10	51	834.381
#16	HMX1	40	1	41	14.144
#17	CEBPA	39	11	50	2140.524
#18	HR	38	8	46	16199.58
#19	ELF4	37	8	45	518.534
#20	POU2F1	37	7	44	731.692
#21	MMP14	36	13	49	1036.661
#22	SOX15	35	0	35	0
#23	ZNF446	34	7	41	364.932
#24	KLF9	34	13	47	1029.255
#25	MZF1	34	7	41	237.181
#26	MECOM	34	12	46	475.142
#27	NFYC	34	9	43	713.138
#28	ZNF277	33	10	43	1479.67
#29	PPARA	33	8	41	2584.813
#30	CSDA	33	16	49	1601.274
#31	RARG	33	5	38	1756.315
#32	VTN	33	12	45	1677.901
#33	HHEX	32	12	44	4132.976
#34	CREM	32	15	47	3002.044
#35	ZNF148	31	13	44	625.121
#36	NR1I3	31	7	38	321.774
#37	LZTR1	31	10	41	2711.158
#38	FOXA2	31	15	46	3961.29
#39	SOX9	31	14	45	1647.678
#40	SUPT4H1	31	6	37	301.115
#41	CNOT8	30	11	41	972.359
#42	HMGA1	30	11	41	1004.362
#43	CREB3L1	30	17	47	1644.248
#44	ADNP	30	10	40	2373.237
#45	RORC	30	10	40	1409.675
#46	USF2	30	12	42	1152.172
#47	TAF12	30	6	36	238.792
#48	HCFC1	30	7	37	643.608
#49	POU6F1	29	9	38	882.616
#50	FOSL1	29	13	42	3658.809
#51	RCAN1	29	13	42	2342.752
#52	CITED2	28	13	41	2756.241
#53	HSF4	28	8	36	539.001
#54	NFIL3	28	9	37	4760.672
#55	TCF3	27	9	36	678.532
#56	HCLS1	27	5	32	846.92
#57	RAX	27	3	30	33.203
#58	HSF2	27	8	35	460.839
#59	THRA	27	5	32	229.764
#60	NFIB	26	19	45	5599.598
#61	TWIST1	26	9	35	3873.508
#62	TRIM28	26	18	44	4100.661
#63	CREBL2	26	15	41	3948.707
#64	CDX2	25	14	39	9939.944
#65	HNF1B	25	18	43	2591.238
#66	MLXIPL	25	9	34	1746.494
#67	ZNF202	25	6	31	399.233
#68	ZNF444	25	11	36	668.387
#69	HEYL	25	6	31	97.587
#70	ARNT	25	7	32	1144.392
#71	TSC22D4	25	9	34	1513.964
#72	E2F3	24	12	36	473.187
#73	HNRNPK	24	9	33	1153.832
#74	PCGF2	24	13	37	2535.415
#75	C11orf9	24	11	35	352.547
#76	MYOG	24	2	26	7.789
#77	LASS2	24	9	33	5021.423
#78	HNF4A	24	11	35	938.879
#79	PROX1	23	12	35	918.519
#80	E2F4	23	8	31	815.266
#81	FUBP1	23	11	34	874.828
#82	GABPA	22	11	33	465.176
#83	TCF7L2	22	16	38	812.572
#84	SNAPC2	22	6	28	1713.744
#85	CREB1	22	11	33	1255.62
#86	TCF25	22	11	33	1148.97
#87	KLF11	22	13	35	711.651
#88	MNX1	22	8	30	494.383
#89	HDAC2	22	8	30	773.914
#90	SMAD3	22	11	33	2586.81
#91	MEIS2	22	20	42	3254.756
#92	SNAPC4	22	15	37	875.426
#93	SOX10	21	4	25	539.582
#94	HOXB2	21	9	30	1440.758
#95	SIM2	21	13	34	1831.989
#96	SP3	21	11	32	654.445
#97	STAT5B	21	9	30	678.628
#98	CBFA2T2	21	11	32	1617.857
#99	POU5F1B	20	14	34	6048.623
#100	ZNF45	20	13	33	687.152
#101	CTNNB1	20	11	31	2023.615
#102	MITF	20	22	42	3071.669
#103	ZNF238	20	18	38	2538.974
#104	ZNF193	20	12	32	1691.915
#105	UBN1	20	12	32	623.147
#106	DMTF1	20	17	37	3243.019
#107	XBP1	20	17	37	1460.616
#108	HIF1A	20	10	30	1021.552
#109	ATF1	20	11	31	2103.647
#110	MNT	20	8	28	102.318
#111	MEF2D	20	6	26	196.959
#112	LZTS1	19	11	30	222.533
#113	ZNF189	19	19	38	3366.026
#114	FOXO4	19	2	21	21.851
#115	EVX1	19	11	30	366.579
#116	NPAS2	19	13	32	941.487
#117	ENO1	19	14	33	372.785
#118	RUNX1	18	16	34	1138.811
#119	FOXD1	18	12	30	1938.912
#120	NR1I2	18	16	34	1361.015
#121	NR5A2	18	15	33	4783.991
#122	FOXN3	18	18	36	1241.325
#123	FOXM1	18	15	33	3009.904
#124	TCF4	18	9	27	1369.137
#125	MYOD1	18	8	26	726.352
#126	TFE3	18	10	28	617.679
#127	TCF7	18	13	31	788.931
#128	BCL3	18	16	34	1309.239
#129	TCF12	18	13	31	1420.937
#130	MEF2C	17	11	28	1935.12
#131	HDAC1	17	19	36	3282.084
#132	SPI1	17	10	27	1989.224
#133	STAT1	17	12	29	3422.143
#134	ZNF187	17	8	25	615.296
#135	SMAD4	17	13	30	417.189
#136	ELF1	17	10	27	957.602
#137	EPAS1	17	12	29	951.134
#138	GTF2I	17	13	30	1442.394
#139	KLF5	17	14	31	581.797
#140	MSX1	17	10	27	2151.002
#141	HOXB5	17	12	29	1940.181
#142	STAT6	17	16	33	1398.773
#143	POU2F2	17	6	23	2530.195
#144	ZEB1	17	16	33	1796.22
#145	MYCL1	17	10	27	1154.604
#146	GTF2IRD1	17	22	39	3080.578
#147	REST	17	9	26	285.819
#148	NR4A1	17	11	28	1467.786
#149	GATA2	17	9	26	1047.708
#150	TCF15	17	6	23	79.929
#151	ZSCAN16	16	15	31	2362.446
#152	ELK3	16	16	32	1019.756
#153	TFEB	16	15	31	818.497
#154	RXRB	16	13	29	1164.684
#155	RELA	16	11	27	1784.122
#156	ZFHX3	16	15	31	2644.565
#157	PRRX2	16	12	28	460.518
#158	HMG20A	16	17	33	14878.067
#159	ADNP2	16	13	29	3982.818
#160	NR3C1	16	11	27	1802.393
#161	RFX5	16	10	26	2121.236
#162	IKZF1	16	14	30	2469.885
#163	NR1H3	16	17	33	954.367
#164	NANOG	16	12	28	6884.037
#165	HOXC4	16	13	29	509.336
#166	ZNF219	15	12	27	913.968
#167	HOXA9	15	5	20	237.295
#168	NFYB	15	15	30	1884.14
#169	SMAD5	15	14	29	542.11
#170	MAFB	15	14	29	2593.385
#171	ARID3A	15	11	26	1672.018
#172	TCEAL1	15	14	29	1932.009
#173	PLAGL2	15	15	30	2546.248
#174	ELF3	15	21	36	1005.983
#175	SOX12	15	16	31	1377.576
#176	SPDEF	15	5	20	51.539
#177	NFE2L3	15	12	27	882.858
#178	ZNF281	15	15	30	3571.024
#179	TARDBP	15	11	26	647.125
#180	HOXA1	15	14	29	3850.545
#181	AR	14	13	27	397.863
#182	HOXB6	14	11	25	1438.535
#183	IRF3	14	13	27	791.018
#184	YEATS4	14	12	26	1039.226
#185	E2F8	14	13	27	834.859
#186	ZKSCAN5	14	9	23	304.032
#187	HOXB1	14	5	19	64.798
#188	NR2F6	14	13	27	937.174
#189	SCMH1	14	12	26	977.12
#190	ZNF133	14	15	29	1741.618
#191	NFYA	14	15	29	457.813
#192	MSRB2	14	14	28	1032.294
#193	CSRNP2	14	13	27	1334.385
#194	GLI3	14	9	23	155.047
#195	PHF1	14	12	26	506.481
#196	RUNX3	14	10	24	318.343
#197	E2F5	14	15	29	1241.047
#198	NOLC1	14	16	30	628.388
#199	KLF2	14	18	32	2318.318
#200	ONECUT2	14	14	28	811.495
#201	SALL2	14	16	30	958.973
#202	ZEB2	14	14	28	669.719
#203	TGIF2	13	17	30	1733.694
#204	FBXW7	13	18	31	395.073
#205	ZNF232	13	15	28	3699.665
#206	TEF	13	12	25	1055.735
#207	IRF7	13	22	35	1417.237
#208	TAF4	13	11	24	767.068
#209	LASS6	13	19	32	3666.203
#210	NOTCH1	13	18	31	875.497
#211	IRF8	13	14	27	1131.531
#212	HOXA11	13	9	22	2461.868
#213	BLZF1	13	13	26	660.57
#214	ETV7	13	9	22	200.54
#215	SOX11	13	15	28	1299.736
#216	SIX1	13	14	27	1506.608
#217	HOPX	13	10	23	525.37
#218	FOXJ2	13	14	27	467.413
#219	GATAD2A	13	14	27	1067.139
#220	FOXA1	13	15	28	1361.471
#221	SMAD2	13	7	20	179.954
#222	GABPB1	13	12	25	809.953
#223	TEAD4	13	23	36	2744.052
#224	BHLHE41	13	17	30	1320.213
#225	ARID4A	13	16	29	2034.807
#226	STAT2	12	15	27	688.386
#227	HNRNPAB	12	16	28	2407.079
#228	HMGA2	12	15	27	2196.291
#229	MGA	12	19	31	3158.274
#230	GATA3	12	13	25	615.187
#231	ETV4	12	12	24	273.87
#232	ZKSCAN1	12	15	27	1268.482
#233	STRN3	12	13	25	1384.999
#234	HOXB7	12	11	23	988.324
#235	ZNF75D	12	15	27	6140.777
#236	KDM5B	12	15	27	910.894
#237	ESR1	12	12	24	1919.697
#238	IRX5	12	13	25	927.39
#239	RORA	12	17	29	1056.488
#240	TBX3	12	16	28	1235.711
#241	TAF5	12	20	32	4220.016
#242	CUX2	12	16	28	500.569
#243	TFCP2L1	12	13	25	2467.875
#244	SPEN	12	9	21	762.541
#245	ELK1	12	11	23	476.13
#246	ATF3	12	13	25	2459.652
#247	PRRX1	12	11	23	2131.681
#248	PKNOX2	12	13	25	1269.436
#249	PBX2	12	11	23	707.426
#250	YY1	11	13	24	723.241
#251	FOS	11	13	24	1608.16
#252	IRF6	11	18	29	947.601
#253	ARNT2	11	15	26	2678.024
#254	HMGB2	11	12	23	2554.343
#255	VDR	11	13	24	502.668
#256	MAF	11	17	28	810.014
#257	PLSCR1	11	22	33	4030.459
#258	CREBZF	11	10	21	254.521
#259	ATF2	11	10	21	195.396
#260	HES1	11	17	28	759.252
#261	RBCK1	11	19	30	1269.8
#262	RXRA	11	14	25	647.985
#263	DLX2	11	6	17	284.72
#264	YBX1	11	12	23	698.753
#265	TEAD3	11	14	25	800.42
#266	E2F1	11	13	24	1113.727
#267	HOXB3	11	8	19	18363.86
#268	VAV1	11	8	19	435.04
#269	PITX3	11	12	23	175.891
#270	TULP4	11	7	18	396.505
#271	NFX1	11	17	28	458.202
#272	LHX5	11	10	21	146.945
#273	UBP1	11	14	25	1075.446
#274	PURA	10	17	27	1267.523
#275	MYBL2	10	14	24	1764.295
#276	GRHL2	10	16	26	1022.975
#277	AFF4	10	13	23	528.663
#278	ATF4	10	10	20	263.762
#279	GATAD1	10	14	24	643.505
#280	GBX1	10	11	21	638.969
#281	TSC22D3	10	25	35	1903.771
#282	ZFP36L2	10	16	26	943.902
#283	PLAG1	10	13	23	2975.064
#284	CREB3L2	10	20	30	6121.876
#285	PEG3	10	20	30	2346.612
#286	AHCTF1	10	15	25	2029.754
#287	TCFL5	10	19	29	1947.433
#288	RELB	10	13	23	1193.815
#289	NR1D2	10	19	29	1325.475
#290	TAF1B	10	14	24	1430.2
#291	MEIS3P1	10	15	25	360.395
#292	NR2C1	10	13	23	517.575
#293	FOXO1	10	15	25	1524.4
#294	FLI1	10	16	26	818.131
#295	RCOR1	10	9	19	17356.605
#296	TSC22D1	9	18	27	772.043
#297	GAS7	9	18	27	1339.703
#298	TRPS1	9	11	20	502.901
#299	KDM5A	9	19	28	295.801
#300	PPARD	9	16	25	729.578
#301	SIX2	9	12	21	1845.692
#302	CBFB	9	17	26	922.486
#303	STAT3	9	14	23	270.899
#304	CEBPD	9	17	26	859.743
#305	KLF12	9	16	25	1351.521
#306	PAX8	9	8	17	132.237
#307	ZKSCAN4	9	12	21	217.942
#308	MTA1	9	13	22	1296.083
#309	GCFC1	9	15	24	2930.514
#310	FOXJ1	9	19	28	2348.899
#311	PTTG1	9	10	19	1183.043
#312	PPARG	9	21	30	1247.486
#313	AHR	9	16	25	3530.72
#314	TFDP1	9	19	28	1887.893
#315	HIF3A	9	10	19	20352.271
#316	ZNF93	9	16	25	484.176
#317	JUNB	8	19	27	2345.6
#318	ZNF217	8	11	19	538.663
#319	ALX1	8	12	20	1585.148
#320	NFATC1	8	21	29	1423.47
#321	NFAT5	8	12	20	1831.239
#322	EGR2	8	14	22	493.901
#323	TCF7L1	8	25	33	1881.366
#324	HOXB13	8	14	22	3619.311
#325	RUNX1T1	8	17	25	2837.984
#326	ESRRA	8	6	14	512.306
#327	TFEC	8	14	22	1459.861
#328	FOXC1	8	16	24	284.645
#329	SMAD6	8	18	26	1371.769
#330	ZFHX4	8	23	31	4985.642
#331	ZNF500	8	16	24	351.217
#332	ERG	8	9	17	335
#333	PBX3	8	27	35	1724.431
#334	FOSB	8	13	21	2231.69
#335	SATB2	8	23	31	3269.677
#336	TSC22D2	8	11	19	659.228
#337	REL	8	14	22	712.457
#338	NFE2L2	8	16	24	545.023
#339	MAFG	8	20	28	417.477
#340	SLC30A9	8	12	20	1400.034
#341	TRIM22	8	17	25	1596.22
#342	ZBTB48	8	19	27	1611.752
#343	SOX5	8	16	24	839.545
#344	ZKSCAN3	8	14	22	489.432
#345	NFATC4	8	9	17	146.85
#346	SNAI2	8	21	29	1809.816
#347	POU3F1	8	11	19	167.986
#348	ZNF83	8	16	24	1658.842
#349	KLF15	8	16	24	380.315
#350	RERE	7	18	25	516.798
#351	EGR1	7	15	22	2594.543
#352	FOXO3	7	18	25	1172.78
#353	ESRRG	7	16	23	3034.109
#354	IRF2	7	18	25	2176.586
#355	CTBP1	7	16	23	431.359
#356	MAX	7	19	26	1157.298
#357	PITX1	7	15	22	1259.226
#358	JUND	7	13	20	932.84
#359	MEIS1	7	19	26	1336.049
#360	NCOR1	7	19	26	1626.121
#361	TFCP2	7	15	22	652.401
#362	NFIC	7	20	27	973.557
#363	FOXF2	7	13	20	781.904
#364	E2F6	7	15	22	586.863
#365	TFAP2A	7	17	24	405.397
#366	MYCN	7	18	25	2205.681
#367	HAND2	7	11	18	215.498
#368	PAX6	7	16	23	1713.124
#369	SCML1	7	18	25	668.48
#370	SOLH	7	23	30	873.289
#371	BCL11B	7	12	19	306.145
#372	BTAF1	7	14	21	961.467
#373	ERF	7	17	24	1325.551
#374	ZFPM2	7	11	18	318.096
#375	HOXA5	7	17	24	796.827
#376	BCL6	7	17	24	1365.246
#377	NFKB2	7	10	17	1224.342
#378	HOXD1	7	21	28	1322.951
#379	SREBF2	7	16	23	1477.552
#380	TSHZ2	6	14	20	1602.35
#381	ELK4	6	19	25	1032.248
#382	C2orf3	6	13	19	179.804
#383	FOSL2	6	24	30	1072.865
#384	BUD31	6	14	20	637.683
#385	SP140	6	8	14	273.635
#386	TAF7	6	13	19	659.475
#387	GATA4	6	18	24	923.874
#388	AEBP1	6	10	16	224.767
#389	TRIM29	6	18	24	254.913
#390	CEBPB	6	15	21	1155.761
#391	RARA	6	15	21	564.322
#392	NFATC3	6	14	20	3204.418
#393	MSX2	6	10	16	282.819
#394	ZNF24	6	15	21	396.468
#395	ETV5	6	19	25	984.871
#396	ZNF274	6	12	18	621.106
#397	IRF9	6	14	20	939.554
#398	FOXF1	6	10	16	441.849
#399	CDKN2A	6	20	26	1015.576
#400	NR2F1	6	22	28	820.363
#401	ETS2	6	19	25	1334.927
#402	ZNF91	6	19	25	350.506
#403	TBX10	6	10	16	106.186
#404	NFE2L1	6	16	22	801.419
#405	AFF1	6	17	23	356.505
#406	ELF2	5	8	13	130.878
#407	MSC	5	19	24	559.024
#408	WT1	5	10	15	289.838
#409	SLC26A3	5	12	17	478.342
#410	ZSCAN18	5	27	32	548.509
#411	EHF	5	11	16	104.104
#412	SPIB	5	14	19	803.431
#413	MAFF	5	21	26	2123.259
#414	HMBOX1	5	16	21	1081.506
#415	ATF6	5	12	17	154.837
#416	JUN	5	19	24	2923.773
#417	TP53	5	16	21	563.632
#418	HEY1	5	25	30	1601.958
#419	HIRA	5	11	16	2130.281
#420	ZNF140	5	13	18	200.407
#421	ZNF268	5	15	20	262.104
#422	HNF4G	5	14	19	244.533
#423	BHLHE40	5	20	25	868.9
#424	LMO4	5	19	24	435.445
#425	PHTF1	5	16	21	179.874
#426	TFAP2C	5	13	18	362.874
#427	KLF7	5	20	25	189.937
#428	KLF6	5	21	26	928.353
#429	ZNF165	4	18	22	2091.132
#430	TGIF1	4	19	23	632.037
#431	BATF	4	17	21	6148.752
#432	ZNF85	4	12	16	228.867
#433	RXRG	4	10	14	944.847
#434	NR0B1	4	12	16	1060.065
#435	ATF6B	4	7	11	33.449
#436	ZNF167	4	20	24	1047.673
#437	SLC2A4RG	4	15	19	1287.914
#438	SMAD1	4	14	18	148.961
#439	MEOX2	4	16	20	979.61
#440	MYC	4	28	32	805.964
#441	CREB5	4	18	22	1970.037
#442	ARNTL	4	17	21	180.259
#443	GATA6	4	21	25	684.364
#444	SATB1	4	18	22	1673.914
#445	ZNF174	4	20	24	458.378
#446	ARNTL2	4	21	25	1451.954
#447	NR4A3	4	13	17	210.931
#448	HEY2	4	15	19	985.926
#449	ZNF323	4	14	18	207.188
#450	ZGPAT	4	13	17	366.82
#451	BACH1	4	13	17	197.21
#452	ZFP36L1	4	16	20	262.887
#453	TBX2	4	18	22	596.005
#454	RB1	4	16	20	439.148
#455	NKX3-1	4	19	23	2262.342
#456	SOX13	4	21	25	322.592
#457	RARB	3	15	18	553.523
#458	TFAM	3	21	24	917.394
#459	FOXK2	3	21	24	506.097
#460	RFXANK	3	18	21	309.607
#461	ZBTB38	3	19	22	743.828
#462	ETV1	3	22	25	324.891
#463	EN1	3	5	8	544.146
#464	NR3C2	3	18	21	1099.125
#465	DLX4	3	17	20	794.622
#466	PBX1	3	24	27	781.904
#467	ZHX2	3	18	21	704.074
#468	POU2F3	3	8	11	556.041
#469	DDIT3	3	15	18	128.494
#470	DBP	3	18	21	156.871
#471	KLF4	3	25	28	1243.285
#472	BACH2	3	15	18	171.81
#473	TFDP2	3	21	24	2046.02
#474	HOXD4	3	15	18	1097.679
#475	CNOT7	3	16	19	1566.646
#476	CLOCK	2	17	19	157.681
#477	BTG2	2	21	23	310.192
#478	HOXA10	2	17	19	670.061
#479	HSF1	2	15	17	29.657
#480	HOXC10	2	12	14	245.088
#481	IRF1	2	17	19	372.865
#482	ZNF131	2	13	15	127.94
#483	KLF10	2	21	23	1053.811
#484	MEF2A	2	16	18	1135.377
#485	ZNF117	2	15	17	520.202
#486	ONECUT1	2	20	22	670.365
#487	SREBF1	1	21	22	88.662
#488	STAT4	1	24	25	123.706
#489	SIM1	1	10	11	630.025
#490	FOXG1	1	10	11	1159.61
#491	NR4A2	1	15	16	174.974
#492	PITX2	1	11	12	32.245
#493	ASCL1	1	17	18	150.898
#494	LHX2	1	16	17	42.608
#495	LEF1	1	31	32	211.864
#496	ZIC1	1	30	31	143.512
#497	ATF5	0	21	21	0
#498	ZNF33B	0	15	15	0
#499	CREBBP	0	16	16	0
#500	WNT5A	0	25	25	0