Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXI1	99	7	106	5552.253
#2	ZSCAN12	65	3	68	2388.344
#3	ZNF197	47	2	49	10761.243
#4	PAX3	44	5	49	1865.855
#5	ZNF207	38	1	39	1639.655
#6	HMX1	37	6	43	3603.186
#7	POU2F2	34	2	36	1402.448
#8	TFCP2L1	34	8	42	4586.548
#9	ZNF91	34	8	42	4607.712
#10	TAL1	34	9	43	2513.255
#11	E2F4	32	5	37	1246.654
#12	THRB	31	4	35	695.824
#13	NR2C1	31	3	34	3986.43
#14	SLC26A3	29	1	30	3663.997
#15	MNX1	28	4	32	1227.291
#16	THRA	28	4	32	12748.87
#17	ZNF287	28	6	34	1261.663
#18	NPAS2	28	6	34	3502.501
#19	MLL	27	6	33	10805.33
#20	SPDEF	27	2	29	1146.352
#21	RARG	26	2	28	61.28
#22	NFYB	26	8	34	2976.965
#23	YBX1	26	6	32	2311.831
#24	ZNF263	26	8	34	454.001
#25	NFX1	25	5	30	806.531
#26	ZNF232	25	5	30	277.728
#27	TRIM29	24	7	31	472.649
#28	CREB3L1	24	4	28	359.546
#29	MZF1	24	4	28	1080.05
#30	DLX2	24	9	33	4089.212
#31	PAX4	24	9	33	4373.964
#32	ZNF323	23	7	30	2698.531
#33	ETV4	23	5	28	2112.686
#34	HCLS1	23	9	32	1321.229
#35	VTN	23	6	29	390.425
#36	HOXB3	23	5	28	2720.048
#37	FLI1	23	1	24	17.555
#38	IRF7	23	13	36	4352.238
#39	HNF1A	22	7	29	1497.494
#40	AHR	22	11	33	6309.362
#41	SMAD5	22	7	29	6855.799
#42	TSC22D1	22	6	28	2150.329
#43	RUNX2	21	5	26	9892.538
#44	ISL1	21	11	32	1238.424
#45	IKZF4	21	7	28	2366.844
#46	SALL1	21	11	32	2356.382
#47	EPAS1	21	10	31	1770.523
#48	NR5A2	21	7	28	1087.885
#49	ADNP	21	7	28	698.187
#50	ELF5	21	6	27	1035.982
#51	ELF4	20	10	30	1417.818
#52	GRHL2	20	5	25	2790.076
#53	NOLC1	20	12	32	3157.011
#54	ZEB2	20	7	27	2540.094
#55	GATA3	19	12	31	7551.6
#56	BHLHE41	19	6	25	982.249
#57	ESRRG	19	8	27	548.62
#58	KLF10	18	6	24	1285.855
#59	ONECUT1	18	7	25	820.683
#60	RCOR1	18	4	22	663.837
#61	FOXA2	18	6	24	904.205
#62	NFE2L3	18	5	23	574.932
#63	NFIL3	18	7	25	966.761
#64	ENO1	17	9	26	2945.123
#65	ZNF238	17	11	28	5145.061
#66	KDM5B	17	6	23	497.08
#67	PHTF1	17	4	21	748.712
#68	CCRN4L	17	8	25	3637.903
#69	EVX1	17	6	23	715.643
#70	TFDP1	17	10	27	1518.791
#71	CNOT8	17	7	24	3740.319
#72	FOXA1	17	6	23	4019.889
#73	ELK3	17	9	26	4327.91
#74	ZBTB17	17	8	25	420.003
#75	NFYA	17	3	20	361.9
#76	NFYC	16	6	22	3219.426
#77	KLF12	16	4	20	43.816
#78	SIX3	16	10	26	516.682
#79	MSX2	16	7	23	1128.407
#80	NR2F1	16	7	23	1990.862
#81	KDM5A	16	11	27	1225.727
#82	ELF2	16	6	22	970.609
#83	PURA	16	5	21	1562.998
#84	ATF1	16	8	24	853.199
#85	NKX2-5	16	6	22	517.879
#86	STAT5B	16	9	25	8298.844
#87	YY1	15	4	19	3344.759
#88	FUBP1	15	10	25	1421.227
#89	SPIB	15	7	22	1479.96
#90	DBP	15	9	24	2803.061
#91	LZTS1	15	2	17	40.363
#92	CNBP	15	4	19	477.899
#93	HLF	15	11	26	5312.861
#94	TBX1	15	3	18	68.045
#95	ZNF155	15	5	20	2315.298
#96	ASCL1	15	4	19	475.665
#97	POU3F1	15	11	26	4164.413
#98	USF2	15	7	22	3745.138
#99	TGIF1	15	10	25	2742.923
#100	ZNF93	15	11	26	3211.392
#101	RUNX3	15	6	21	543.383
#102	BACH1	15	10	25	2120.581
#103	TCF4	15	9	24	2430.836
#104	PPARG	15	7	22	2215.373
#105	HMGB1	14	7	21	5039.218
#106	HIF3A	14	7	21	478.185
#107	ZNF500	14	4	18	1508.941
#108	ZNF187	14	4	18	795.109
#109	LZTR1	14	11	25	1543.729
#110	SNAI2	14	7	21	2459.981
#111	TARDBP	14	9	23	2826.18
#112	GCM1	14	9	23	327.078
#113	C2orf3	14	9	23	688.894
#114	TFAP2A	14	11	25	1211.153
#115	ONECUT2	14	8	22	2384.654
#116	SP3	13	10	23	2520.392
#117	REST	13	7	20	1117.057
#118	CBFA2T2	13	7	20	1278.444
#119	ZKSCAN3	13	10	23	2545.57
#120	NR6A1	13	5	18	809.776
#121	EMX1	13	10	23	1502.549
#122	SMAD3	13	7	20	3295.751
#123	CUX2	12	7	19	268.899
#124	PKNOX1	12	7	19	2351.423
#125	MYT1L	12	6	18	2995.23
#126	TP53	12	10	22	1906.742
#127	HCFC1	12	9	21	810.426
#128	TFAP2B	12	9	21	1175.365
#129	NR3C1	12	9	21	820.946
#130	ZNF193	12	11	23	1774.321
#131	EGR3	12	4	16	883.6
#132	NKX3-1	12	9	21	1278.476
#133	CTBP1	12	11	23	2204.766
#134	ZNF140	12	11	23	1121.712
#135	RFXANK	12	10	22	3429.844
#136	GTF2H4	12	9	21	1478.119
#137	CBFB	12	12	24	953.387
#138	GABPA	11	5	16	937.615
#139	PEG3	11	12	23	1076.42
#140	MLLT10	11	7	18	1447.542
#141	HOXA9	11	13	24	4506.528
#142	JUN	11	11	22	977.98
#143	ZNF217	11	10	21	1108.448
#144	FOXC1	11	9	20	2931.108
#145	PA2G4	11	17	28	2736.363
#146	NOTCH1	11	13	24	10719.091
#147	CEBPB	11	12	23	2436.721
#148	HMG20B	11	4	15	488.53
#149	ETV6	11	5	16	166.331
#150	HMGA1	11	10	21	787.451
#151	CREB1	11	9	20	3469.356
#152	CREB5	11	13	24	1972.367
#153	TGIF2	11	3	14	64.824
#154	ZHX2	11	13	24	1515.331
#155	IRF6	11	11	22	2094.642
#156	AHCTF1	11	5	16	367.994
#157	HSF2	11	14	25	3780.365
#158	ZNF83	11	12	23	2233.602
#159	EGR1	11	9	20	1483.557
#160	GTF2H3	11	7	18	337.99
#161	HMG20A	10	11	21	10002.793
#162	IRF8	10	4	14	459.739
#163	CREBL2	10	9	19	1441.731
#164	MECOM	10	9	19	327.69
#165	NR1H4	10	11	21	2013.608
#166	HNRNPK	10	9	19	1389.337
#167	POU6F2	10	9	19	1360.053
#168	BCL3	10	13	23	2302.317
#169	POU3F4	10	7	17	6164.348
#170	ZNF174	10	8	18	171.841
#171	NR4A1	10	4	14	1443.66
#172	PBX3	10	10	20	6001.356
#173	E2F1	10	4	14	939.193
#174	RUNX1T1	10	7	17	3776.211
#175	TFE3	10	10	20	4115.863
#176	PHF1	10	10	20	3812.907
#177	HAND1	10	9	19	925.799
#178	FOXJ3	10	14	24	10285.153
#179	TSC22D2	10	9	19	3777.178
#180	NR1D2	10	11	21	860.288
#181	MTA2	10	3	13	221.559
#182	ZKSCAN1	10	8	18	1457.59
#183	MEF2C	10	11	21	1760.801
#184	NEUROD1	10	7	17	642.51
#185	HNF4A	10	11	21	2342.386
#186	ETV3	10	9	19	700.295
#187	ATF5	9	11	20	4225.381
#188	TCF7	9	15	24	913.163
#189	EHF	9	12	21	958.36
#190	FOXF1	9	11	20	15228.373
#191	E2F5	9	12	21	2181.292
#192	TFEB	9	9	18	978.53
#193	TBX3	9	12	21	1339.283
#194	ZNF24	9	7	16	1199.519
#195	NPAT	9	6	15	207.15
#196	ZKSCAN4	9	7	16	746.445
#197	PTTG1	9	11	20	1235.804
#198	UBP1	9	8	17	1924.229
#199	TRIM25	9	8	17	2701.45
#200	POU4F2	9	7	16	172.531
#201	NFE2L1	9	14	23	2491.21
#202	MAFB	9	9	18	404.061
#203	HHEX	9	4	13	800.329
#204	ZFP36L2	9	10	19	2467.112
#205	MYCN	9	15	24	3740.649
#206	NR3C2	9	12	21	1689.134
#207	HDAC2	9	14	23	3972.909
#208	NR2E3	9	10	19	3207.791
#209	PKNOX2	9	5	14	303.443
#210	ESRRA	9	14	23	1358.699
#211	CDKN2A	9	1	10	13.258
#212	HNF1B	9	14	23	4458.041
#213	CEBPA	9	12	21	2519.453
#214	SOX12	9	13	22	3475.04
#215	IRF1	8	11	19	1039.366
#216	TFAP2C	8	8	16	287.707
#217	STAT3	8	10	18	4129.621
#218	KLF5	8	10	18	2158.862
#219	IRF3	8	9	17	1361.821
#220	PPARA	8	6	14	62.17
#221	XBP1	8	9	17	1704.86
#222	FOXF2	8	9	17	3333.041
#223	CEBPD	8	10	18	6160.578
#224	HMBOX1	8	8	16	357.234
#225	GSC2	8	7	15	593.077
#226	NR1H2	8	5	13	860.125
#227	TP63	8	8	16	1242.124
#228	JUND	8	5	13	1921.817
#229	CITED2	8	10	18	3667.996
#230	STAT1	8	11	19	764.811
#231	DMRT1	8	6	14	100.732
#232	STRN3	8	10	18	1435.656
#233	SMAD4	8	6	14	314.573
#234	TCF7L2	8	6	14	1155.939
#235	ARNT2	8	11	19	500.951
#236	MMP14	8	8	16	5114.115
#237	CSDA	8	9	17	749.813
#238	GATAD1	8	10	18	1693.585
#239	SNAPC5	8	6	14	254.513
#240	HOXD11	8	6	14	478.138
#241	ETS2	8	9	17	4498.436
#242	MEOX1	8	5	13	91.493
#243	ETV5	8	9	17	949.289
#244	HESX1	8	9	17	3175.359
#245	GLI2	8	2	10	312.612
#246	ZHX3	8	3	11	63.622
#247	MITF	8	12	20	1878.555
#248	DDIT3	8	15	23	1703.017
#249	HOXD4	7	12	19	2289.717
#250	MLX	7	11	18	2305.398
#251	ETS1	7	8	15	719.396
#252	CNOT7	7	7	14	1921.426
#253	SATB2	7	7	14	1055.114
#254	ZNF157	7	10	17	468.452
#255	SREBF2	7	11	18	6025.501
#256	HDAC1	7	9	16	1350.572
#257	PBX1	7	5	12	131.245
#258	TAF1B	7	5	12	269.679
#259	NR2F6	7	8	15	963.012
#260	ETV2	7	10	17	294.97
#261	PLSCR1	7	13	20	849.826
#262	NR1H3	7	6	13	223.906
#263	TCF21	7	11	18	779.81
#264	SPEN	7	11	18	2742.815
#265	HEY1	7	9	16	493.019
#266	RCAN1	7	14	21	2053.746
#267	MYCL1	7	7	14	211.141
#268	IRF5	7	9	16	253.522
#269	TCF25	7	10	17	3362.437
#270	LASS6	7	12	19	3941.359
#271	YEATS4	7	14	21	2372.568
#272	ZNF85	7	7	14	228.621
#273	ZEB1	7	9	16	2221.549
#274	HOXC8	7	7	14	3003.399
#275	MTA1	6	10	16	1226.14
#276	REL	6	12	18	1214.732
#277	SIX1	6	10	16	2940.547
#278	EGR2	6	9	15	2464.21
#279	FOXD1	6	14	20	2446.702
#280	ZBTB38	6	8	14	1197.775
#281	HOXC10	6	13	19	585.311
#282	CTCF	6	11	17	1480.786
#283	ELK4	6	5	11	82.704
#284	HOXB9	6	7	13	6789.106
#285	TCF20	6	7	13	2171.138
#286	GTF2I	6	14	20	2612.32
#287	ADNP2	6	9	15	1402.487
#288	GAS7	6	7	13	1376.554
#289	ATF3	6	9	15	222.295
#290	BCL6	6	14	20	309.549
#291	RUNX1	6	5	11	2021.217
#292	ERG	6	13	19	1273.621
#293	FOXO1	6	9	15	703.759
#294	ZNF189	6	9	15	439.246
#295	HOXA7	6	12	18	753.226
#296	KLF1	6	4	10	88.245
#297	ATF6	6	12	18	2366.99
#298	HSF1	6	7	13	560.069
#299	SIM1	6	12	18	765.716
#300	LEF1	6	14	20	3874.676
#301	SOX15	6	9	15	850.816
#302	KLF6	6	9	15	2178.822
#303	RBCK1	6	11	17	536.001
#304	TADA3	6	11	17	4631.662
#305	ELF3	6	22	28	2405.849
#306	GATA4	6	5	11	172.693
#307	WNT5A	6	10	16	780.513
#308	MYC	6	14	20	2512.754
#309	ZFHX3	6	14	20	2950.745
#310	JUNB	6	17	23	4320.507
#311	ZFP36L1	6	11	17	1732.08
#312	HOXB6	6	8	14	200.168
#313	NCOR1	5	16	21	3537.137
#314	BLZF1	5	8	13	675.098
#315	PITX2	5	9	14	694.193
#316	FOSB	5	6	11	173.671
#317	TAF13	5	6	11	60.632
#318	PAX8	5	15	20	1040.117
#319	ATF2	5	11	16	1335.527
#320	MAF	5	10	15	2539.06
#321	HES1	5	11	16	1168.316
#322	RFX3	5	7	12	512.799
#323	NFIB	5	13	18	3114.775
#324	SOX18	5	9	14	242.489
#325	TRIM22	5	13	18	889.857
#326	KLF9	5	17	22	1237.541
#327	NR2F2	5	15	20	2831.21
#328	NKX2-1	5	10	15	12239.365
#329	BHLHE40	5	18	23	1110.52
#330	C11orf9	5	12	17	1040.485
#331	SCML1	5	11	16	853.264
#332	TEAD4	5	8	13	55.977
#333	RERE	5	10	15	617.611
#334	TFAM	5	7	12	732.493
#335	IRF2	5	12	17	1818.647
#336	SPI1	5	10	15	431.751
#337	MSRB2	5	13	18	1756.229
#338	TFEC	5	10	15	1135.766
#339	ZNF148	5	9	14	1252.586
#340	ZNF175	5	7	12	1887.991
#341	TCF12	5	9	14	1267.214
#342	ZNF274	5	8	13	7098.689
#343	SCAND1	5	13	18	1357.168
#344	TBX19	5	7	12	192.346
#345	NFKB2	5	13	18	1596.418
#346	FOXO3	5	12	17	902.338
#347	MYF5	5	10	15	2327.241
#348	TEAD3	5	11	16	3226.125
#349	PRRX1	5	12	17	1259.769
#350	GATA2	4	9	13	990.125
#351	POU4F3	4	12	16	847.301
#352	MEIS2	4	8	12	888.825
#353	ETV7	4	6	10	221.579
#354	EN2	4	10	14	291.783
#355	NR1I3	4	7	11	62.002
#356	BTG2	4	13	17	1282.292
#357	POU3F3	4	5	9	50.822
#358	SATB1	4	13	17	4160.334
#359	HNRNPAB	4	14	18	2494.67
#360	ZFPM2	4	9	13	1770.113
#361	CUX1	4	14	18	989.178
#362	TAF10	4	17	21	1245.127
#363	RXRA	4	20	24	641.174
#364	SOX10	4	10	14	943.202
#365	RB1	4	14	18	366.823
#366	PPARD	4	7	11	36.579
#367	FOS	4	9	13	3558.846
#368	NR0B1	4	8	12	3189.577
#369	CREBZF	4	15	19	1948.378
#370	FOXD3	4	6	10	218.8
#371	NFAT5	4	12	16	2525.926
#372	HOPX	4	15	19	1500.032
#373	SOX21	4	8	12	1380.075
#374	ELF1	4	12	16	506.846
#375	FOXM1	4	12	16	321.483
#376	NFE2L2	4	11	15	2876.56
#377	HSF4	4	9	13	571.092
#378	ARNT	4	14	18	1461.674
#379	ETV1	4	15	19	1919.454
#380	SCAND2	4	9	13	2063.409
#381	PRDM2	4	14	18	855.767
#382	SLC2A4RG	4	14	18	927.969
#383	SLC30A9	3	10	13	581.771
#384	ZNF236	3	10	13	171.034
#385	EDF1	3	8	11	957.269
#386	BUD31	3	14	17	1798.819
#387	RBPJ	3	13	16	1305.154
#388	NR4A2	3	11	14	209.97
#389	ZNF135	3	8	11	4894.325
#390	WT1	3	7	10	59.232
#391	HOXA1	3	10	13	289.419
#392	FOXN3	3	15	18	269.098
#393	SCRT1	3	11	14	465.717
#394	PHOX2A	3	6	9	1598.008
#395	HOXA10	3	12	15	608.964
#396	ATF6B	3	12	15	7058.231
#397	HOXB13	3	13	16	1712.438
#398	HOXD3	3	10	13	3985.955
#399	RORB	3	9	12	697.243
#400	SIX2	3	14	17	850.209
#401	SOX17	3	12	15	491.515
#402	HOXD1	3	12	15	588.892
#403	HOXA4	3	8	11	756.14
#404	HIC1	3	10	13	1664.904
#405	SUPT4H1	3	13	16	7213.017
#406	MNT	3	11	14	200.866
#407	EN1	3	12	15	1118.465
#408	SP140	3	7	10	117.377
#409	KLF4	3	13	16	608.73
#410	CREB3L2	3	12	15	2088.786
#411	E2F3	2	12	14	928.591
#412	CREBBP	2	11	13	146.422
#413	HOXC4	2	14	16	1990.279
#414	KLF11	2	11	13	381.834
#415	MEF2A	2	13	15	373.24
#416	TCEAL1	2	10	12	1536.4
#417	HMGA2	2	8	10	1223.776
#418	ERF	2	14	16	3565.261
#419	PCGF2	2	11	13	1258.169
#420	TAF7	2	11	13	62.037
#421	HOXD10	2	11	13	733.126
#422	GCFC1	2	6	8	98.689
#423	MSC	2	11	13	7485.67
#424	MEF2D	2	8	10	87.138
#425	GATA6	2	13	15	2030.405
#426	BRD8	2	10	12	694.551
#427	E2F8	2	12	14	157.735
#428	HOXB5	2	6	8	521.74
#429	TSC22D3	2	11	13	279.388
#430	HEY2	2	14	16	377.166
#431	STAT6	2	12	14	1533.144
#432	ZNF131	2	14	16	95.64
#433	PLAGL2	2	5	7	86.873
#434	OVOL1	2	18	20	464.242
#435	IKZF1	2	15	17	946.101
#436	HOXB7	2	15	17	456.653
#437	HIF1A	2	10	12	419.995
#438	LHX1	2	10	12	722.606
#439	IRF9	2	8	10	1778.485
#440	TRPS1	2	7	9	15.32
#441	ESR1	2	11	13	690.75
#442	CLOCK	2	8	10	77.018
#443	KLF3	2	8	10	691.008
#444	RARB	2	10	12	66.138
#445	TWIST1	2	16	18	794.96
#446	AFF1	2	17	19	1121.832
#447	TULP4	1	9	10	69.888
#448	LASS2	1	13	14	310.368
#449	PITX1	1	8	9	9124.915
#450	TLX2	1	11	12	1502.279
#451	SMAD6	1	13	14	869.086
#452	MAFF	1	17	18	52.319
#453	ATF4	1	11	12	62.835
#454	TBX2	1	10	11	466.457
#455	KLF2	1	11	12	475.137
#456	MEOX2	1	15	16	50.825
#457	ESR2	1	8	9	423.806
#458	AEBP1	1	14	15	58.062
#459	ARNTL	1	6	7	61.187
#460	IRF4	1	9	10	54.733
#461	SMAD1	1	10	11	283.14
#462	PLAG1	1	12	13	1599.487
#463	SMAD2	1	10	11	512.485
#464	HOXB1	1	7	8	178.363
#465	NR4A3	1	8	9	1116.785
#466	CREM	1	6	7	14.738
#467	VDR	1	13	14	437.515
#468	HOXA5	1	6	7	97.813
#469	HOXB2	1	15	16	3562.659
#470	CTNNB1	1	8	9	18.101
#471	TCF3	1	12	13	52.414
#472	ZNF45	1	9	10	26.36
#473	ZNF165	1	11	12	154.819
#474	SOLH	1	11	12	59.285
#475	TCFL5	1	12	13	38.906
#476	ZGPAT	1	12	13	373.189
#477	MEIS1	1	13	14	640.901
#478	ZNF3	1	7	8	60.703
#479	IRX5	1	14	15	26.204
#480	ASCL2	1	14	15	5370.149
#481	SIM2	1	14	15	133.66
#482	ZSCAN18	1	15	16	1404.471
#483	HMGB2	0	14	14	0
#484	FOSL2	0	13	13	0
#485	LMO4	0	19	19	0
#486	EGR4	0	13	13	0
#487	SOX13	0	12	12	0
#488	SREBF1	0	15	15	0
#489	MEIS3P1	0	13	13	0
#490	ZNF80	0	12	12	0
#491	POU4F1	0	12	12	0
#492	AR	0	12	12	0
#493	POU1F1	0	10	10	0
#494	DRAP1	0	12	12	0
#495	SOX11	0	13	13	0
#496	SOX4	0	11	11	0
#497	TRIM28	0	16	16	0
#498	KLF7	0	9	9	0
#499	SOX9	0	21	21	0
#500	ZNF268	0	10	10	0