Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	CREM	65	10	75	12805.541
#2	SATB2	64	8	72	1001.823
#3	MAFB	56	6	62	200.036
#4	HCLS1	56	1	57	24.268
#5	MTA2	52	2	54	529.596
#6	SNAI2	51	3	54	44.402
#7	C11orf9	51	7	58	2603.215
#8	NR1I2	49	12	61	1136.022
#9	PRRX1	49	6	55	318.057
#10	STAT1	48	9	57	567.539
#11	STRN3	48	4	52	465.432
#12	RXRB	47	4	51	388.325
#13	FOSL2	47	6	53	537.854
#14	EHF	47	3	50	804.305
#15	IRF6	46	1	47	27.517
#16	ZBTB48	46	8	54	4676.062
#17	AEBP1	44	6	50	1013.841
#18	STAT2	44	9	53	2762.602
#19	MEF2C	44	4	48	46.847
#20	NR3C1	43	6	49	119.065
#21	ETS2	43	11	54	768.887
#22	TSHZ3	42	4	46	106.361
#23	HOXB2	42	7	49	3663.678
#24	ETV1	41	8	49	200.412
#25	HIC1	40	8	48	434.172
#26	FLI1	40	3	43	1838.905
#27	USF1	39	6	45	688.86
#28	EBF1	39	8	47	327.823
#29	ETS1	39	6	45	438.05
#30	CTNNB1	38	10	48	790.9
#31	ZFP36L2	37	10	47	935.279
#32	HOPX	37	5	42	3415.797
#33	CDX2	37	7	44	1550.587
#34	IKZF1	37	5	42	580.662
#35	NFIB	36	10	46	1102.146
#36	HHEX	36	14	50	990.614
#37	NFATC1	36	7	43	684.213
#38	TCF3	36	9	45	874.935
#39	FOXA2	36	11	47	870.715
#40	TP53	36	11	47	1230.408
#41	SREBF1	35	7	42	598.998
#42	PROX1	35	11	46	736.979
#43	ZNF174	34	12	46	1697.626
#44	BATF	34	21	55	4564.696
#45	NR3C2	33	12	45	1317.462
#46	SPDEF	33	15	48	689.269
#47	VAV1	33	12	45	1007.33
#48	MEIS2	33	10	43	340.709
#49	ERG	32	12	44	969.491
#50	TFAP2A	32	16	48	999.615
#51	ZNF238	32	9	41	1891.412
#52	HOXA10	32	6	38	2718.8
#53	NOTCH1	32	15	47	1281.866
#54	PITX2	31	13	44	2406.147
#55	FOXO1	31	12	43	1129.19
#56	MMP14	31	13	44	2811.428
#57	HNF4G	31	7	38	143.952
#58	NR4A2	29	10	39	523.279
#59	BCL6	29	11	40	5064.174
#60	ZSCAN18	29	18	47	2769.01
#61	STAT5B	29	16	45	1077.608
#62	ETV6	28	6	34	150.669
#63	RB1	28	9	37	756.722
#64	TFCP2L1	28	11	39	2399.355
#65	ZEB1	28	12	40	220.563
#66	HOXA3	28	3	31	303.469
#67	HES6	28	13	41	939.966
#68	BHLHE40	28	9	37	564.315
#69	NR0B1	28	16	44	2912.77
#70	TRIM22	27	8	35	217.675
#71	HOXA5	27	5	32	1630.604
#72	SMAD9	27	13	40	1375.592
#73	SATB1	27	16	43	1698.611
#74	HOXB13	26	14	40	1997.385
#75	EGR2	26	12	38	392.27
#76	OVOL1	26	17	43	2266.737
#77	TBX1	26	14	40	965.165
#78	TCF4	26	16	42	960.199
#79	BCL3	25	12	37	772.573
#80	EGR3	25	8	33	685.308
#81	WNT5A	25	8	33	202.903
#82	MAF	25	12	37	747.517
#83	HOXB1	25	16	41	442.728
#84	RARA	25	18	43	1071.044
#85	FOSL1	25	8	33	983.901
#86	CREB3L1	25	13	38	446.739
#87	MEIS1	24	16	40	455.326
#88	CSDA	24	14	38	1019.732
#89	NR2F6	24	10	34	207.967
#90	GLIS2	24	8	32	116.518
#91	YY1	24	18	42	623.051
#92	ENO1	24	17	41	1756.947
#93	GAS7	24	9	33	144.437
#94	HNF4A	23	20	43	886.147
#95	POU2F2	23	15	38	6141.547
#96	CBFA2T3	23	9	32	2247.134
#97	TRPS1	23	17	40	1295.535
#98	MXD1	23	7	30	1070.293
#99	TRERF1	22	16	38	555.978
#100	MESP2	22	22	44	2220.5
#101	NR4A1	22	3	25	299.188
#102	MBD1	22	15	37	1355.406
#103	C12orf28	22	13	35	638.414
#104	MEOX1	22	11	33	164.356
#105	PHF1	21	14	35	1318.627
#106	SOX4	21	10	31	1081.33
#107	FUBP1	21	12	33	933.508
#108	FOXQ1	21	18	39	1408.504
#109	TWIST2	21	11	32	5141.926
#110	HEY1	21	17	38	1038.511
#111	NR4A3	21	14	35	777.972
#112	HMGA2	21	18	39	1750.395
#113	RUNX1T1	21	10	31	211.712
#114	ISX	21	8	29	447.634
#115	EGR1	21	15	36	858.214
#116	ZIC2	21	12	33	314.363
#117	CNOT7	21	15	36	2138.847
#118	MLL	21	16	37	1017.117
#119	ZFPM2	21	8	29	415.924
#120	VAX2	20	15	35	1018.049
#121	ZEB2	20	11	31	2598.23
#122	NR5A2	20	15	35	1168.013
#123	SIX4	20	15	35	808.139
#124	FOXD1	20	14	34	934.882
#125	TFE3	20	12	32	656.098
#126	SLC26A3	20	16	36	859.29
#127	ZIC5	20	13	33	1511.798
#128	ARNT	20	12	32	419.163
#129	SOX10	20	16	36	1627.911
#130	KLF4	20	11	31	600.374
#131	TWIST1	20	7	27	410.03
#132	SPI1	20	8	28	619.043
#133	CDKN2A	19	23	42	1465.599
#134	HOXD10	19	9	28	796.21
#135	IRX3	19	9	28	699.117
#136	FOXC1	18	15	33	302.206
#137	SIX1	18	16	34	730.382
#138	TAL1	18	20	38	1751.158
#139	PBX1	18	20	38	2510.579
#140	SMAD3	18	14	32	684.967
#141	RFXAP	18	16	34	1318.979
#142	HOXA13	18	11	29	513.419
#143	SOX8	18	23	41	3448.723
#144	CITED1	17	11	28	718.128
#145	FOXA1	17	17	34	1647.516
#146	ISL1	17	14	31	615.126
#147	HOXD4	17	17	34	2050.667
#148	NFAT5	17	19	36	1251.76
#149	HOXA11	17	15	32	1504.207
#150	FOXL2	17	21	38	1731.835
#151	HOXC9	17	17	34	2332.582
#152	HNF1B	17	17	34	1930.499
#153	MEIS3	17	14	31	3031.497
#154	ZNF434	17	22	39	2040.969
#155	SMAD2	17	19	36	1507.075
#156	HOXA4	16	7	23	174.502
#157	ZNF90	16	14	30	1461.021
#158	SOX18	16	9	25	100.313
#159	CREB5	16	20	36	2080.226
#160	ETV5	16	17	33	358.118
#161	MLLT10	16	16	32	1076.449
#162	HOXA7	16	8	24	456.677
#163	ZBTB38	16	17	33	1774.988
#164	VENTX	16	13	29	892.077
#165	ZNF83	16	18	34	928.443
#166	NR2E3	16	15	31	1031.767
#167	RCAN1	16	18	34	864.218
#168	SMAD6	16	15	31	725.16
#169	ZNF444	16	17	33	1330.336
#170	HOXA1	16	8	24	1023.551
#171	AHCTF1	15	20	35	1873.792
#172	C2orf3	15	16	31	1811.134
#173	NFE2	15	11	26	632.575
#174	FOXJ1	15	20	35	1066.207
#175	HIF3A	15	9	24	709.341
#176	TAF1B	15	20	35	1573.212
#177	RORA	15	14	29	1078.241
#178	ZNF117	15	15	30	1824.368
#179	FOS	15	6	21	232.491
#180	ESR1	15	14	29	906.527
#181	ARNT2	15	21	36	895.029
#182	PAX6	15	19	34	1165.45
#183	FOXE1	15	14	29	2581.928
#184	HOXD9	15	10	25	742.651
#185	NKX2-1	15	17	32	1643.442
#186	SALL1	15	14	29	515.405
#187	CREBZF	15	14	29	1564.927
#188	HCFC1	15	16	31	899.452
#189	NRL	15	23	38	2140.734
#190	ETV7	15	19	34	1035.994
#191	LMO4	15	16	31	519.77
#192	TFEC	15	7	22	142.541
#193	ELF5	15	17	32	682.237
#194	SCAND1	15	26	41	3612.42
#195	MYF5	14	17	31	1717.513
#196	ZSCAN10	14	16	30	3644.461
#197	NPAT	14	15	29	679.356
#198	NFKB2	14	13	27	1198.311
#199	PKNOX2	14	15	29	840.35
#200	NEUROG1	14	18	32	1425.244
#201	ALS2CR8	14	12	26	1110.785
#202	GRHL3	14	23	37	1202.078
#203	DLX3	14	18	32	1430.094
#204	CSRNP3	14	23	37	1147.601
#205	ONECUT2	14	12	26	787.501
#206	MZF1	14	18	32	840.127
#207	FOXK2	14	14	28	536.219
#208	SOX13	14	17	31	1452.931
#209	MECOM	14	22	36	1194.556
#210	NR2F1	14	12	26	339.332
#211	TBX2	14	12	26	460.502
#212	RARB	14	19	33	1449.377
#213	HMGB2	14	21	35	1087.485
#214	PKNOX1	14	17	31	919.179
#215	ZNF483	14	21	35	13578.167
#216	ATOH1	14	9	23	826.442
#217	CBL	14	16	30	666.393
#218	CREBBP	13	15	28	916.428
#219	GLIS3	13	13	26	522.708
#220	HOXA9	13	10	23	457.456
#221	POU4F1	13	16	29	801.207
#222	RCOR2	13	17	30	727.324
#223	FOXR2	13	20	33	2328.211
#224	RORB	13	18	31	936.506
#225	BACH2	13	12	25	857.444
#226	ATF7	13	20	33	857.351
#227	NFATC2	13	18	31	1706.092
#228	DMRT2	13	19	32	954.439
#229	NPAS1	13	15	28	473.114
#230	HOXA2	13	12	25	570.363
#231	KDM5A	13	21	34	1288.491
#232	VTN	13	14	27	831.459
#233	FOSB	13	8	21	839.644
#234	ATF3	13	6	19	134.638
#235	KLF9	13	20	33	1278.867
#236	SOX11	13	12	25	203.273
#237	TBX3	13	21	34	1381.878
#238	HOXB6	13	17	30	721.947
#239	ATF6B	13	16	29	745.376
#240	HES5	13	26	39	1449.408
#241	REST	13	16	29	1264.739
#242	HR	13	15	28	1601.728
#243	NKX2-3	13	15	28	491.055
#244	HOXD11	13	12	25	1195.534
#245	TRIM29	13	22	35	2665.159
#246	MSX2	13	25	38	1539.833
#247	SNAI3	13	15	28	1133.116
#248	TAF13	12	20	32	2224.793
#249	SIM2	12	18	30	962.591
#250	NR1I3	12	16	28	841.965
#251	FOXO3	12	14	26	218.097
#252	SPIB	12	16	28	1205.047
#253	TSC22D2	12	22	34	1030.665
#254	MKX	12	16	28	379.778
#255	PPARA	12	16	28	1884.417
#256	PITX1	12	19	31	767.308
#257	ZNF167	12	19	31	1271.185
#258	IRX1	12	17	29	1702.908
#259	ZNF24	12	15	27	439.673
#260	ZNF397	12	21	33	444.801
#261	TADA3	12	19	31	1284.45
#262	NPAS2	12	24	36	860.177
#263	NOBOX	12	13	25	539.31
#264	ZSCAN12	12	17	29	1012.338
#265	SP4	12	18	30	1618.257
#266	ZNF446	12	20	32	1618.705
#267	ZXDC	12	19	31	754.313
#268	ALX3	12	19	31	1297.64
#269	TBR1	12	20	32	1087.714
#270	MGA	12	23	35	2316.55
#271	TFAP2C	12	23	35	1872.951
#272	CTBP1	12	15	27	964.255
#273	ARX	12	15	27	667.205
#274	ZNF92	12	18	30	1590.518
#275	TAF4	12	13	25	2246.897
#276	NKX6-2	12	13	25	1027.954
#277	RXRG	12	19	31	1354.815
#278	SP140	12	8	20	173.476
#279	KCNH8	12	13	25	1508.913
#280	ZNF3	12	14	26	752.951
#281	E2F2	12	20	32	2067.964
#282	WT1	11	24	35	1855.48
#283	TFAP2D	11	14	25	658.22
#284	ZNF207	11	12	23	936.211
#285	TEAD2	11	17	28	507.692
#286	TBX5	11	17	28	1172.456
#287	PAX4	11	19	30	735.132
#288	THRB	11	21	32	876.037
#289	GATA5	11	10	21	733.397
#290	ZSCAN23	11	18	29	918.551
#291	ZSCAN4	11	18	29	1204.906
#292	FOXC2	11	22	33	992.579
#293	IRX5	11	16	27	660.695
#294	NKX2-5	11	11	22	862.64
#295	HOXC11	11	22	33	1365.607
#296	SIM1	11	20	31	929.331
#297	EMX1	11	12	23	1062.781
#298	RUNX3	11	14	25	1055.363
#299	IKZF4	11	17	28	1194.369
#300	FOXG1	11	19	30	1720.844
#301	ZNF219	11	18	29	1397.141
#302	NFATC4	11	15	26	1365.627
#303	NR1H4	11	22	33	672.152
#304	GLI2	11	18	29	2475.177
#305	TLX1	11	20	31	466.94
#306	PLAG1	11	15	26	705.304
#307	TP73	10	17	27	399.509
#308	SOX2	10	25	35	1058.378
#309	BHLHE41	10	17	27	368.941
#310	HOXB8	10	21	31	532.609
#311	RORC	10	18	28	398.072
#312	L3MBTL4	10	23	33	747.967
#313	NANOG	10	20	30	773.769
#314	POU2F3	10	11	21	164.433
#315	DLX1	10	15	25	659.825
#316	ZNF256	10	19	29	855.471
#317	BNC1	10	15	25	1693.695
#318	ZIC3	10	23	33	1679.356
#319	LHX9	10	16	26	777.47
#320	SIN3A	10	20	30	3293.391
#321	SP3	10	24	34	646.366
#322	TULP4	10	17	27	1185.957
#323	POU2F1	10	17	27	1089.77
#324	HDX	10	21	31	494.429
#325	GATA3	10	20	30	1486.185
#326	FOXH1	10	16	26	1144.645
#327	NFIX	10	21	31	1088.587
#328	GCM1	10	12	22	1072.553
#329	ZSCAN20	10	17	27	907.397
#330	FOXN4	10	16	26	1071.359
#331	POU3F1	10	20	30	1047.504
#332	SOX21	10	22	32	1191.564
#333	HESX1	10	18	28	1131.181
#334	MYF6	10	19	29	683.06
#335	TFDP3	10	15	25	510.307
#336	KLF1	10	18	28	1567.61
#337	MIXL1	10	24	34	1137.254
#338	TEF	10	9	19	284.226
#339	ZNF33B	10	15	25	1142.646
#340	RFX3	10	17	27	683.089
#341	POU6F1	10	21	31	1880.224
#342	FOXK1	9	24	33	962.465
#343	ZFP42	9	17	26	1493.27
#344	GSX1	9	15	24	1106.483
#345	HMG20B	9	16	25	1012.592
#346	TCF25	9	24	33	1654.984
#347	PGBD1	9	15	24	423.294
#348	ZFP37	9	17	26	661.851
#349	POU3F4	9	19	28	1456.931
#350	TCF20	9	13	22	678.782
#351	CRX	9	17	26	997.106
#352	MYT1L	9	16	25	950.693
#353	ZNF287	9	24	33	1142.881
#354	PDX1	9	17	26	943.045
#355	MYCN	9	18	27	662.117
#356	ZSCAN2	9	19	28	702.021
#357	KLF12	9	18	27	1148.576
#358	TFAP2B	9	20	29	1145.869
#359	SCAND3	9	19	28	1072.031
#360	HEY2	9	12	21	984.069
#361	ZNF71	9	19	28	690.229
#362	SOX6	9	21	30	778.043
#363	POU1F1	9	14	23	614.853
#364	SIX2	9	22	31	956.294
#365	ZFHX2	9	18	27	900.748
#366	DLX4	8	21	29	1063.583
#367	ZFHX4	8	15	23	459.706
#368	VSX1	8	21	29	822.776
#369	SLC2A4RG	8	28	36	1692.444
#370	PCGF2	8	18	26	1179.263
#371	ST18	8	17	25	1077.121
#372	PGR	8	18	26	1448.812
#373	FOXI1	8	19	27	902.502
#374	LHX8	8	19	27	686.377
#375	RUNX2	8	18	26	2045.6
#376	ELK1	8	28	36	1624.076
#377	ZSCAN1	8	19	27	704.436
#378	ZNF496	8	21	29	744.289
#379	MESP1	8	15	23	505.244
#380	SNAPC5	8	16	24	681.091
#381	THRA	8	22	30	914.924
#382	ASCL2	8	20	28	759.142
#383	FOXP3	8	20	28	520.191
#384	PPARD	8	18	26	813.335
#385	FOXS1	8	19	27	625.449
#386	GATAD2A	8	18	26	571.028
#387	GATA4	8	22	30	830.212
#388	POU4F2	8	19	27	857.892
#389	PLSCR1	8	23	31	1044.633
#390	ZNF396	8	21	29	1026.538
#391	ZNF70	8	16	24	573.145
#392	TSHZ2	8	16	24	592.567
#393	ZNF500	8	17	25	539.999
#394	LHX2	8	16	24	593.908
#395	IRX4	7	13	20	659.793
#396	ASCL1	7	20	27	833.777
#397	TLX3	7	20	27	833.456
#398	PHOX2B	7	16	23	401.906
#399	ANKRD30A	7	21	28	986.557
#400	ATF2	7	23	30	690.04
#401	FOXD3	7	20	27	1789.826
#402	PRDM2	7	16	23	678.612
#403	NEUROD2	7	21	28	1114.075
#404	ZIC1	7	17	24	1300.943
#405	BARX1	7	21	28	1059.632
#406	GATAD1	7	18	25	1301.451
#407	ELK4	7	17	24	1028.311
#408	PAX7	7	19	26	1197.083
#409	HNRNPAB	7	18	25	936.04
#410	NR2E1	7	18	25	618.52
#411	ZNF132	7	20	27	743.938
#412	CREB3L3	7	21	28	809.354
#413	POU5F2	7	17	24	641.103
#414	MLX	7	18	25	417.339
#415	SOX30	7	22	29	939.29
#416	ESX1	7	21	28	1898.396
#417	JUND	7	23	30	794.339
#418	FOXP2	7	17	24	487.563
#419	BLZF1	7	14	21	307.785
#420	IKZF3	7	16	23	521.992
#421	POU6F2	7	24	31	889.207
#422	EN1	7	16	23	487.908
#423	ZNF93	6	16	22	843.778
#424	ZKSCAN3	6	19	25	456.422
#425	ZFHX3	6	10	16	265.343
#426	ZNF157	6	16	22	904.84
#427	ZFP36L1	6	17	23	525.694
#428	ZNF81	6	21	27	571.089
#429	TBX6	6	18	24	283.06
#430	TSC22D3	6	22	28	855.551
#431	HOXD3	6	22	28	1012.658
#432	ZNF80	6	18	24	779.507
#433	HOXD13	6	17	23	412.845
#434	HOXD1	6	14	20	547.231
#435	ONECUT1	6	21	27	608.543
#436	OLIG2	6	18	24	587.171
#437	ZNF639	6	21	27	997.783
#438	PBX3	6	14	20	602.096
#439	ESR2	6	20	26	765.031
#440	TLX2	6	14	20	832.982
#441	NFIC	6	13	19	310.658
#442	NCOR1	6	17	23	511.147
#443	LMX1A	6	18	24	624.852
#444	EGR4	6	15	21	1306.084
#445	GATA1	6	14	20	561.976
#446	TBX15	6	18	24	682.192
#447	DMRT1	6	18	24	504.987
#448	MEOX2	6	8	14	62.462
#449	TCF21	6	13	19	87.104
#450	IRX2	6	19	25	775.19
#451	NEUROD1	6	21	27	344.492
#452	ZNF85	6	22	28	713.55
#453	EN2	6	25	31	839.431
#454	LZTS1	6	21	27	5024.022
#455	ZNF154	6	18	24	526.809
#456	EPAS1	6	17	23	409.274
#457	KDM5B	6	18	24	616.613
#458	SCAND2	6	19	25	561.991
#459	CUX2	5	23	28	595.612
#460	SPIC	5	20	25	696.289
#461	OTX2	5	13	18	339.658
#462	ISL2	5	19	24	175.563
#463	ESRRB	5	17	22	571.475
#464	SIX3	5	25	30	889.709
#465	GSX2	5	16	21	454.807
#466	POU3F2	5	17	22	690.964
#467	FOXN3	5	22	27	443.738
#468	PAX3	5	20	25	1053.79
#469	MYT1	5	14	19	454.332
#470	ZNF175	5	11	16	230.908
#471	PTH	5	15	20	351.603
#472	KLF17	5	17	22	502.205
#473	ZNF135	4	17	21	380.646
#474	NFIA	4	19	23	545.742
#475	ZNF134	4	19	23	203.609
#476	BCL11B	4	19	23	229.006
#477	NFYA	4	18	22	671.278
#478	RUNX1	4	21	25	495.761
#479	NR5A1	4	13	17	215.734
#480	DLX6	4	21	25	273.607
#481	RERE	4	20	24	532.818
#482	ESRRG	4	17	21	264.73
#483	BRD8	4	18	22	451.76
#484	SMAD4	4	17	21	687.961
#485	GLI3	4	17	21	355.523
#486	SOX5	4	22	26	469.324
#487	TP63	4	11	15	218.674
#488	HIRA	4	14	18	413.023
#489	SOX1	4	30	34	711.557
#490	ZNF215	4	19	23	371.037
#491	HSF5	3	22	25	877.126
#492	MITF	3	22	25	266.847
#493	PAX8	3	25	28	644.552
#494	TBX20	3	21	24	307.919
#495	HLF	3	21	24	270.606
#496	DLX2	3	12	15	359.734
#497	NANOGNB	3	22	25	396.544
#498	AFF4	3	21	24	1069.212
#499	MYNN	3	21	24	301.633
#500	ZNF131	2	24	26	233.813