Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	IRF2	59	1	60	15.579
#2	ATF1	53	3	56	773.228
#3	RELA	51	8	59	626.815
#4	RARG	47	2	49	117.194
#5	TAF4	46	9	55	722.257
#6	RELB	44	5	49	181.719
#7	MAFF	42	11	53	677.193
#8	HDAC2	42	7	49	552.447
#9	ZKSCAN1	42	9	51	1415.161
#10	MLXIPL	42	0	42	0
#11	NPAT	41	4	45	307.385
#12	PRRX2	40	4	44	1168.914
#13	ADNP	39	9	48	1291.086
#14	BACH1	39	4	43	4311.06
#15	ZNF189	38	7	45	124.465
#16	CTCF	38	4	42	2447.418
#17	SP3	38	8	46	318.559
#18	NFYC	37	10	47	582.201
#19	KLF9	36	17	53	732.219
#20	FOXJ3	36	11	47	4170.105
#21	ATF2	34	7	41	652.953
#22	IRF3	34	6	40	237.413
#23	HNRNPAB	34	9	43	650.374
#24	TCF15	34	3	37	83.324
#25	SNAPC5	33	11	44	1105.044
#26	PKNOX2	33	4	37	232.459
#27	E2F4	33	9	42	942.347
#28	MEF2C	33	11	44	390.609
#29	SNAPC2	32	4	36	1326.608
#30	MGA	32	8	40	180.248
#31	NCOR1	32	4	36	518.797
#32	CBFA2T3	31	19	50	2553.251
#33	MLX	31	9	40	1807.063
#34	CIR1	31	5	36	275.352
#35	TFAM	31	12	43	3318.862
#36	HMG20A	31	10	41	1204.93
#37	NFE2L2	31	11	42	300.032
#38	FLI1	31	7	38	1253.539
#39	ETV4	30	8	38	327.708
#40	SOX15	30	4	34	45.52
#41	HR	30	7	37	466.092
#42	NR1H2	29	8	37	284.063
#43	HMX1	29	1	30	8.029
#44	PAX8	29	9	38	490.358
#45	RAX	29	9	38	3324.001
#46	E2F6	28	16	44	2433.111
#47	ZNF444	28	8	36	5837.083
#48	ZNF202	28	11	39	2461.09
#49	BCL3	28	11	39	1064.046
#50	ADNP2	28	12	40	503.841
#51	SOX21	28	7	35	1308.168
#52	PRDM2	28	8	36	644.461
#53	TBX4	26	4	30	174.484
#54	SPDEF	26	5	31	205.525
#55	ARID4A	26	8	34	734.332
#56	GTF2I	26	7	33	1253.208
#57	PHF1	26	14	40	2424.436
#58	ZNF236	25	4	29	522.475
#59	CREBZF	25	14	39	1206.319
#60	HSF4	25	10	35	428.838
#61	ELF4	25	16	41	1451.044
#62	ZNF217	25	12	37	569.379
#63	ELK1	25	12	37	1378.806
#64	ENO1	25	11	36	1245.431
#65	TP53	25	10	35	2142.136
#66	RORA	25	15	40	799.824
#67	ELF2	25	12	37	1185.601
#68	ETV7	25	6	31	9566.335
#69	ZNF75D	24	13	37	944.724
#70	ESRRA	24	8	32	702.714
#71	RBPJ	24	12	36	4859.332
#72	ZNF140	24	13	37	3346.697
#73	ELK4	24	16	40	3367.903
#74	CREBBP	24	12	36	656.67
#75	RCOR1	24	14	38	4293.218
#76	E2F8	24	8	32	879.731
#77	SLC30A9	23	12	35	5149.99
#78	SOX13	23	7	30	2239.014
#79	EGR4	23	6	29	30031.804
#80	SIX1	23	7	30	127.935
#81	ATF4	23	15	38	1205.658
#82	PAX7	23	9	32	503.337
#83	FOXL1	23	7	30	618.451
#84	RUNX3	23	16	39	1984.06
#85	MMP14	23	4	27	717.962
#86	TRIM28	23	12	35	1704.292
#87	REST	22	10	32	314.281
#88	CDX2	22	9	31	231.563
#89	HNF1B	22	5	27	1008.63
#90	RARA	22	20	42	3404.454
#91	TSC22D2	22	13	35	1162.78
#92	ZNF187	22	15	37	2737.82
#93	RORC	21	6	27	2750.147
#94	BARX1	21	8	29	10258.043
#95	NR3C1	21	14	35	1840.269
#96	RFXANK	21	11	32	1037.132
#97	FOXJ1	21	12	33	537.802
#98	HOXC11	21	6	27	184.966
#99	SMAD2	21	12	33	778.811
#100	HNRNPK	21	11	32	504.515
#101	ELF3	21	11	32	11473.416
#102	PHTF1	21	15	36	2530.163
#103	HSF2	20	11	31	1124.754
#104	KLF11	20	15	35	903.545
#105	POU6F1	20	11	31	652.301
#106	LASS2	20	12	32	1579.566
#107	PURA	20	9	29	630.92
#108	NR1D2	20	14	34	652.783
#109	TARDBP	20	10	30	1551.956
#110	NOLC1	20	18	38	3492.837
#111	PTTG1	20	13	33	1670.187
#112	ZSCAN16	19	14	33	687.811
#113	NFYB	19	13	32	2160.025
#114	ZNF232	19	11	30	2922.423
#115	TAF12	19	11	30	451.23
#116	PITX3	19	9	28	17266.224
#117	ELK3	19	11	30	620.905
#118	STAT5A	19	12	31	1811.573
#119	MAX	19	18	37	1897.716
#120	MYOG	19	5	24	74.848
#121	GBX1	19	10	29	625.531
#122	SCAND1	19	13	32	920.875
#123	MAFG	19	12	31	528.464
#124	ARNTL	19	11	30	910.729
#125	AHR	18	15	33	1742.477
#126	SMAD3	18	16	34	1117.95
#127	HMG20B	18	19	37	1329.464
#128	TCF12	18	11	29	904.524
#129	TFAP2C	18	13	31	1856.51
#130	FUBP1	18	12	30	1116.855
#131	KLF7	18	18	36	986.948
#132	EVX1	18	8	26	1667.758
#133	T	18	6	24	4491.891
#134	RXRB	18	9	27	582.813
#135	GABPA	18	11	29	759.018
#136	HINFP	18	13	31	1710.913
#137	SLC2A4RG	18	16	34	1926.681
#138	TFE3	18	11	29	360.918
#139	KLF3	18	16	34	3481.366
#140	MXD1	18	14	32	1110.704
#141	FOSL2	18	17	35	4423.387
#142	ZNF394	18	12	30	624.878
#143	HOXA5	18	13	31	910.58
#144	TAF5	17	14	31	3481.238
#145	TFCP2	17	14	31	316.242
#146	CITED1	17	7	24	364.22
#147	TRPS1	17	10	27	1159.349
#148	ZNF281	17	20	37	2181.004
#149	GTF2H4	17	15	32	660.174
#150	RB1	17	18	35	2052.35
#151	BHLHE41	17	19	36	1007.915
#152	FOXO1	17	13	30	1007.943
#153	NR2C1	17	13	30	488.135
#154	ECSIT	17	9	26	1862.601
#155	FOXO4	17	8	25	112.34
#156	FOS	17	12	29	822.608
#157	GLI3	17	6	23	314.058
#158	PBX2	17	9	26	731.661
#159	TCF3	17	15	32	1519.987
#160	BUD31	17	12	29	557.534
#161	LHX6	17	11	28	1906.818
#162	ATF6B	17	10	27	311.949
#163	EDF1	17	17	34	1601.58
#164	ZNF45	17	15	32	2607.48
#165	ZBTB38	16	14	30	633.397
#166	SMAD4	16	15	31	956.328
#167	NR4A1	16	12	28	1022.131
#168	MEF2A	16	18	34	1173.524
#169	SP140	16	11	27	567.549
#170	CREBL2	16	13	29	1061.509
#171	FOSB	16	9	25	682.615
#172	SIX5	16	5	21	441.531
#173	NFATC3	16	14	30	1541.975
#174	IRF1	16	16	32	693.504
#175	MLL	16	15	31	1484.275
#176	TAF5L	16	21	37	2057.146
#177	STRN3	16	15	31	1068.253
#178	MAFB	16	7	23	953.912
#179	FOXM1	16	7	23	236.614
#180	GATAD1	16	14	30	1054.74
#181	IRF9	16	9	25	617.83
#182	ZNF85	16	7	23	338.439
#183	CREB3L1	15	5	20	112.777
#184	HEY2	15	23	38	2349.767
#185	TCF20	15	12	27	2105.912
#186	STAT2	15	8	23	1272.732
#187	HIRA	15	12	27	920.603
#188	ETV6	15	15	30	1710.97
#189	JUNB	15	16	31	1063.2
#190	MSRB2	15	17	32	1489.274
#191	TGIF2	15	8	23	276.687
#192	SMAD6	15	12	27	1463.567
#193	ATF3	15	11	26	417.661
#194	GABPB1	15	14	29	1082.529
#195	STAT3	15	19	34	4448.018
#196	PA2G4	15	20	35	4416.801
#197	IKZF3	15	16	31	506.147
#198	NFATC1	15	19	34	3954.298
#199	TRIM29	15	7	22	408.843
#200	JUN	15	13	28	1768.772
#201	UBP1	15	19	34	1654.973
#202	JUND	15	17	32	904.181
#203	ZNF238	15	20	35	1372.179
#204	NPAS1	14	11	25	255.614
#205	NR4A2	14	13	27	1345.997
#206	NFKB1	14	11	25	2363.163
#207	ZEB1	14	13	27	521.781
#208	CUX1	14	17	31	2127.391
#209	PPARD	14	8	22	358.065
#210	MSC	14	8	22	713.656
#211	NR1I2	14	9	23	407.858
#212	RCAN1	14	14	28	894.33
#213	PCGF2	14	6	20	811.289
#214	SOX10	14	7	21	23350.998
#215	TFCP2L1	14	7	21	447.587
#216	HOXB1	14	12	26	1443.499
#217	ZNF165	14	18	32	2113.354
#218	AHCTF1	14	16	30	1059.333
#219	E2F3	14	12	26	576.928
#220	KDM5B	13	20	33	6540.826
#221	ZFHX3	13	12	25	1041.487
#222	KLF6	13	13	26	722.113
#223	ZBTB17	13	12	25	788.416
#224	HMGB2	13	20	33	1889.768
#225	IRF7	13	9	22	1555.19
#226	IRF4	13	15	28	691.699
#227	HIF3A	13	4	17	3963.938
#228	LASS6	13	17	30	1790.87
#229	FOXP3	13	8	21	1063.534
#230	LZTS1	13	12	25	663.048
#231	ZNF274	13	16	29	1061.159
#232	E2F5	13	18	31	296.13
#233	USF2	13	13	26	320.28
#234	TFEB	13	21	34	2350.344
#235	MZF1	13	17	30	979.172
#236	HAND2	13	9	22	1061.487
#237	ZNF24	13	11	24	917.182
#238	IKZF1	13	16	29	2941.927
#239	TFDP1	12	13	25	660.776
#240	PLAGL2	12	18	30	2333.747
#241	MYBL2	12	12	24	418.287
#242	SCML2	12	14	26	930.868
#243	HOXB7	12	20	32	1480.154
#244	BTG2	12	18	30	765.488
#245	RXRA	12	20	32	1717.098
#246	HNF4A	12	7	19	2395.367
#247	GSC2	12	8	20	703.702
#248	SPI1	12	12	24	268.879
#249	BHLHE40	12	14	26	717.582
#250	HIC1	12	10	22	288.532
#251	DDIT3	12	20	32	1050.908
#252	PBX1	12	12	24	968.334
#253	ETS2	12	10	22	1901.66
#254	KLF4	11	24	35	1342.655
#255	MAF	11	18	29	1409.266
#256	BACH2	11	23	34	2266.94
#257	FOXO3	11	19	30	2501.965
#258	NFKB2	11	14	25	5762.944
#259	XBP1	11	18	29	1380.584
#260	TCFL5	11	24	35	1283.03
#261	BTAF1	11	16	27	2123.829
#262	ZNF83	11	17	28	1945.241
#263	RFX5	11	15	26	860.881
#264	C2orf3	11	13	24	576.02
#265	TCF25	11	21	32	2538.672
#266	ZNF643	11	14	25	1699.399
#267	ARNTL2	11	16	27	948.584
#268	ZNF3	11	15	26	1612.198
#269	MEF2D	11	13	24	309.304
#270	TSC22D4	11	9	20	985.258
#271	TCEAL1	11	13	24	1565.395
#272	IRF6	11	12	23	454.551
#273	SOX9	11	12	23	1279.601
#274	ZNF434	11	15	26	868.213
#275	ZBTB48	11	15	26	1190.551
#276	LHX3	11	11	22	236.812
#277	ZNF219	11	16	27	324.475
#278	TBP	11	17	28	1321.448
#279	SNAPC4	11	10	21	461.878
#280	NRL	11	16	27	970.894
#281	ZNF131	10	18	28	908.019
#282	TCF4	10	20	30	1260.582
#283	HOXC10	10	5	15	217.084
#284	ELF1	10	20	30	864.38
#285	RNF4	10	12	22	2039.6
#286	HOXC4	10	14	24	1076.09
#287	GCFC1	10	18	28	616.167
#288	LMO4	10	20	30	5253.069
#289	CREB3L2	10	20	30	698.725
#290	REL	10	12	22	875.411
#291	MITF	10	17	27	4146.452
#292	HEY1	10	16	26	751.734
#293	KLF2	10	19	29	939.982
#294	PFDN1	10	14	24	455.553
#295	STAT4	10	19	29	823.231
#296	BATF	10	14	24	968.963
#297	HMGA1	10	18	28	1472.898
#298	HDAC1	10	15	25	1461.183
#299	HHEX	10	16	26	1255.148
#300	STAT1	10	14	24	387.55
#301	CREB1	10	13	23	212.775
#302	SIX2	10	16	26	1590.716
#303	TCF7	10	14	24	610.984
#304	FOXN3	9	19	28	3233.313
#305	ZSCAN18	9	17	26	999.222
#306	IRF8	9	12	21	1415.946
#307	CBFB	9	23	32	1700.408
#308	CSRNP2	9	21	30	2746.965
#309	ZNF167	9	17	26	2177.926
#310	HCLS1	9	17	26	557.926
#311	POU5F1B	9	17	26	537.962
#312	RUNX1	9	17	26	711.516
#313	HOXA9	9	11	20	758.973
#314	TRIM22	9	17	26	852.529
#315	HOPX	9	18	27	1306.172
#316	HOXA10	9	16	25	709.256
#317	HOXA3	9	13	22	19816.509
#318	NR1H3	9	14	23	1563.48
#319	NPAS2	9	7	16	481.299
#320	MTA1	9	16	25	355.346
#321	RUNX2	9	12	21	556.854
#322	KLF10	9	22	31	1438.085
#323	CREB5	9	16	25	944.897
#324	HOXB2	9	17	26	28604.867
#325	ZGPAT	9	8	17	381.763
#326	HEYL	9	7	16	224.06
#327	SATB1	9	23	32	1526.148
#328	SOX4	9	25	34	1433.222
#329	TSC22D3	8	14	22	1070.952
#330	TAF7	8	16	24	3336.362
#331	CNOT8	8	19	27	547.426
#332	NFAT5	8	12	20	615.201
#333	YBX1	8	16	24	1906.513
#334	POU2F2	8	17	25	1568.948
#335	STAT6	8	17	25	1751.907
#336	GATA3	8	15	23	2255.052
#337	TULP4	8	15	23	722.026
#338	RFX1	8	13	21	6022.62
#339	ARNT	8	23	31	775.218
#340	BATF3	8	18	26	1553.911
#341	TCF7L1	8	10	18	1092.883
#342	NR2F6	8	17	25	1613.354
#343	FOXJ2	8	17	25	367.22
#344	NR5A1	8	11	19	131.604
#345	PLAG1	8	19	27	2272.442
#346	VAV1	8	14	22	587.972
#347	TGIF1	8	18	26	2210.295
#348	POU2F1	8	15	23	543.909
#349	CDKN2A	8	24	32	1063.945
#350	ZFP36L1	8	26	34	1179.729
#351	SPEN	8	12	20	322.281
#352	TSHZ2	8	8	16	94.672
#353	GTF2H3	8	16	24	2435.924
#354	AFF1	8	19	27	3002.487
#355	EPAS1	8	17	25	1131.605
#356	TADA3	8	16	24	933.161
#357	ZNF277	8	18	26	980.483
#358	SPIB	8	14	22	5572.202
#359	CBFA2T2	8	16	24	978.668
#360	ARNT2	8	22	30	1563.456
#361	NFE2L3	8	12	20	752.756
#362	FBXW7	8	23	31	3367.133
#363	HSF1	7	14	21	1691.051
#364	DMTF1	7	22	29	15384.742
#365	ETS1	7	16	23	421.406
#366	GATA2	7	12	19	307.064
#367	CNBP	7	12	19	1024.114
#368	TBX21	7	15	22	1252.17
#369	VDR	7	20	27	654.693
#370	CLOCK	7	18	25	1846.924
#371	PRDM1	7	13	20	216.057
#372	ZNF134	7	18	25	944.457
#373	FOXN1	7	11	18	297.466
#374	ESRRG	7	19	26	786.689
#375	NOTCH1	7	16	23	988.576
#376	TP73	7	11	18	1468.377
#377	TEF	7	14	21	942.044
#378	ZNF93	7	16	23	2922.27
#379	NKX2-8	7	12	19	11257.014
#380	C11orf9	7	17	24	1491.963
#381	TBX2	7	12	19	1772.478
#382	TFAP2A	7	6	13	1520.616
#383	CEBPE	7	11	18	177.331
#384	RARB	7	11	18	447.171
#385	ZNF323	7	14	21	2676.771
#386	ZNF193	7	14	21	204.732
#387	MEIS3P1	7	15	22	1273.005
#388	FOXK2	6	22	28	1088.051
#389	NR4A3	6	16	22	2643.51
#390	YY1	6	13	19	447.931
#391	CSDA	6	24	30	1160.245
#392	STAT5B	6	22	28	1776.255
#393	NEUROD2	6	16	22	530.151
#394	KLF5	6	19	25	1247.433
#395	IRF5	6	20	26	2642.093
#396	TAF6	6	19	25	330.308
#397	PEG3	6	21	27	2188.222
#398	HES1	6	18	24	1148.548
#399	ZNF215	6	21	27	768.857
#400	ZNF207	6	20	26	1697.272
#401	RUNX1T1	6	13	19	624.463
#402	ERF	6	14	20	695.046
#403	HMGB1	6	21	27	352.047
#404	POU4F1	6	16	22	341.608
#405	DRAP1	6	15	21	776.753
#406	ESR1	6	24	30	738.91
#407	SUPT4H1	6	15	21	924.112
#408	ZNF148	6	13	19	291.04
#409	MYC	6	25	31	3578.79
#410	MEIS2	6	24	30	1048.232
#411	ALX4	6	10	16	313.434
#412	TP63	6	14	20	1004.826
#413	GAS7	6	15	21	773.274
#414	NFE2L1	6	17	23	748.937
#415	CTBP1	6	16	22	416.974
#416	HOXD1	6	15	21	616.79
#417	KDM5A	6	16	22	880.78
#418	CNOT7	6	20	26	479.158
#419	MYNN	6	18	24	625.736
#420	NFX1	6	21	27	5427.32
#421	MYF6	6	16	22	3183.959
#422	RERE	6	19	25	797.597
#423	SOX12	6	19	25	651.543
#424	NFIL3	5	22	27	691.152
#425	EGR3	5	15	20	2132.662
#426	TAF4B	5	23	28	1236.334
#427	CEBPD	5	21	26	627.975
#428	PBX3	5	19	24	1855.426
#429	MLLT10	5	16	21	1905.988
#430	SRF	5	17	22	767.608
#431	CITED2	5	23	28	1091.829
#432	MYT1L	5	12	17	418.247
#433	TCF7L2	5	17	22	522.474
#434	ZFP36L2	5	25	30	1005.253
#435	AFF4	5	17	22	973.433
#436	HIF1A	5	25	30	482.372
#437	ZNF174	5	21	26	653.527
#438	ZBTB25	5	17	22	557.837
#439	ZNF133	5	16	21	409.247
#440	SATB2	5	21	26	1433.917
#441	ATF6	5	27	32	899.046
#442	ZFPM2	4	13	17	186.41
#443	BCL6	4	18	22	397.403
#444	NKX3-1	4	10	14	2310.03
#445	ZHX2	4	21	25	816.951
#446	TFEC	4	17	21	639.441
#447	MNT	4	21	25	208.371
#448	NFIC	4	20	24	703.07
#449	SUPT6H	4	18	22	1267.489
#450	SMAD1	4	23	27	1760.242
#451	E2F2	4	16	20	1042.997
#452	SMAD5	4	17	21	2768.467
#453	PROX1	4	11	15	364.675
#454	AEBP1	4	16	20	270.294
#455	ELF5	4	17	21	1132.845
#456	UBN1	4	26	30	1022.692
#457	PITX1	4	18	22	1469.273
#458	CTNNB1	4	14	18	160.95
#459	LEF1	4	17	21	335.608
#460	RBCK1	4	13	17	1159.271
#461	BRD8	4	19	23	301.279
#462	TFDP2	4	19	23	1183.303
#463	ZNF91	4	29	33	1145.211
#464	NFYA	4	18	22	170.682
#465	SCML1	4	16	20	264.875
#466	ATF5	3	19	22	712.084
#467	CEBPB	3	23	26	207.579
#468	TAF10	3	25	28	1237.647
#469	ETV5	3	20	23	1321.113
#470	EGR2	3	20	23	683.693
#471	ZNF268	3	15	18	153.21
#472	EGR1	3	15	18	163.779
#473	NFE2	3	13	16	640.034
#474	PAX6	3	14	17	360.619
#475	HOXA1	3	17	20	918.256
#476	SREBF2	3	17	20	147.535
#477	THRA	3	14	17	111.9
#478	PLSCR1	3	18	21	690.287
#479	ETV3	3	12	15	1439.283
#480	MYCN	3	12	15	283.994
#481	FOXA1	3	16	19	317.801
#482	MSL3	3	21	24	439.365
#483	FOXN2	3	22	25	535.079
#484	SOLH	2	19	21	289.128
#485	CREM	2	20	22	241.52
#486	SOX2	2	17	19	97.656
#487	NR2F2	2	10	12	99.444
#488	SREBF1	2	19	21	752.665
#489	ZNF117	2	19	21	832.126
#490	CREB3	2	17	19	120.969
#491	NFIB	2	27	29	860.252
#492	ARID3A	2	16	18	160.381
#493	ESR2	2	18	20	466.627
#494	MBD1	1	14	15	112.177
#495	WNT5A	1	30	31	100.65
#496	TSC22D1	1	28	29	270.993
#497	HMBOX1	1	17	18	75.526
#498	FOXD1	1	15	16	37.174
#499	ETV1	1	24	25	245.659
#500	ZNF263	1	15	16	41.195