Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	IRF6	72	0	72	0
#2	MAFB	71	5	76	183.123
#3	SP1	69	1	70	7.472
#4	STRN3	65	9	74	267.32
#5	MTA2	64	9	73	430.564
#6	ETV5	62	4	66	1556.852
#7	NR3C1	60	5	65	65.736
#8	TSHZ3	60	5	65	1925.419
#9	AEBP1	57	3	60	106.234
#10	MEF2C	56	9	65	108.222
#11	FOXF2	56	5	61	3619.703
#12	SNAI2	56	4	60	52.699
#13	CDX2	55	9	64	2379.365
#14	TCF4	54	3	57	175.493
#15	HCLS1	54	5	59	373.533
#16	PRRX1	54	3	57	97.62
#17	MEIS2	53	9	62	404.45
#18	ZSCAN18	53	12	65	4039.899
#19	TFAP2A	53	9	62	250.148
#20	EHF	53	3	56	29.583
#21	HOPX	52	6	58	2540.405
#22	IKZF1	51	4	55	107.137
#23	STAT1	51	7	58	1524.645
#24	MXD1	51	9	60	657.201
#25	ETS1	51	12	63	825.341
#26	TFCP2L1	50	8	58	204.445
#27	EOMES	50	11	61	322.149
#28	KLF4	47	8	55	136.388
#29	TRIM22	47	8	55	1694.729
#30	NR1I2	46	8	54	468.208
#31	C11orf9	46	9	55	1601.804
#32	MEIS1	46	12	58	179.508
#33	RB1	45	6	51	1271.029
#34	NFE2L2	44	4	48	35.434
#35	NR4A2	44	8	52	348.45
#36	MBD1	44	10	54	1257.076
#37	SLC26A3	44	17	61	790.566
#38	HOXD3	43	13	56	641.342
#39	NFATC3	42	13	55	1528.467
#40	MMP14	42	20	62	3120.023
#41	SATB2	42	7	49	135.697
#42	CBFA2T3	42	10	52	414.941
#43	FOXQ1	41	10	51	865.722
#44	HOXC9	41	15	56	522.673
#45	TWIST1	41	7	48	236.67
#46	SMAD9	41	13	54	640.579
#47	NPAS2	41	12	53	1328.479
#48	EGR2	41	11	52	146.523
#49	HNF4G	40	7	47	108.346
#50	ZFP36L2	40	9	49	404.215
#51	ONECUT2	39	12	51	509.556
#52	FOXD1	39	14	53	704.476
#53	ISX	39	11	50	846.552
#54	TRERF1	39	23	62	1028.32
#55	SPDEF	39	9	48	336.288
#56	TCF21	38	10	48	729.25
#57	LEF1	38	21	59	1388.784
#58	FOXA2	38	14	52	2867.345
#59	NR2F1	37	15	52	1229.444
#60	EBF1	37	11	48	1322.033
#61	USF1	37	16	53	865.106
#62	TAF13	37	21	58	1626.807
#63	ZEB1	37	15	52	2790.022
#64	CREB3L1	36	13	49	312.331
#65	PHF1	36	20	56	1611.987
#66	TCF3	36	13	49	711.819
#67	NKX2-3	36	12	48	4313.039
#68	PURB	35	11	46	693.422
#69	HOXA7	35	4	39	676.114
#70	ZEB2	35	18	53	461.401
#71	MESP1	35	20	55	1557.178
#72	ZNF24	35	17	52	578.542
#73	BCL6	35	17	52	825.929
#74	HHEX	34	20	54	913.096
#75	TFEC	34	21	55	935.984
#76	NR3C2	34	13	47	545.978
#77	HOXA10	33	5	38	620.562
#78	RUNX3	33	18	51	2141.642
#79	FOXL1	33	24	57	1054.691
#80	ZFPM2	32	11	43	441.215
#81	PROX1	32	15	47	941.341
#82	HOXA9	32	0	32	0
#83	ZNF238	31	13	44	638.695
#84	HOXA3	31	12	43	840.789
#85	LMO4	31	14	45	369.004
#86	NFAT5	31	12	43	751.389
#87	TRPS1	31	19	50	1332.565
#88	PKNOX1	31	26	57	1537.45
#89	TWIST2	31	11	42	101.582
#90	HOXB2	31	19	50	621.944
#91	FOXC1	31	20	51	930.535
#92	NR2F6	30	14	44	405.211
#93	ZIC2	30	16	46	319.491
#94	PCGF2	30	21	51	1455.143
#95	PEG3	29	14	43	656.969
#96	ESR1	29	17	46	1299.778
#97	HEY1	29	21	50	1361.853
#98	NR6A1	29	21	50	485.747
#99	HOXB6	29	13	42	342.716
#100	KCNH8	28	16	44	783.634
#101	SOX1	28	27	55	1102.377
#102	ISL1	28	19	47	1046.687
#103	ZNF256	28	17	45	711.281
#104	NANOG	28	18	46	597.118
#105	VAV1	28	15	43	460.98
#106	AHCTF1	28	21	49	1342.816
#107	HEY2	28	21	49	1438.685
#108	HR	28	23	51	962.19
#109	POU3F4	28	21	49	1143.768
#110	YY1	28	19	47	1145.636
#111	TEAD2	27	20	47	798.454
#112	TP63	27	16	43	618.862
#113	HOXA5	27	2	29	32.968
#114	ATOH1	27	13	40	601.426
#115	FOXJ1	27	20	47	1747.941
#116	HOXA4	27	14	41	507.644
#117	GLIS3	27	20	47	293.984
#118	POU4F1	27	23	50	1191.568
#119	NR4A1	27	7	34	1572.264
#120	HMBOX1	27	15	42	636.623
#121	ETV4	27	17	44	777.415
#122	ATF6B	26	18	44	616.397
#123	SMAD3	26	17	43	1252.063
#124	HOXA11	26	8	34	206.463
#125	ZNF83	26	27	53	1821.495
#126	ASCL2	26	21	47	572.104
#127	FOXO3	26	18	44	590.164
#128	ZFHX3	25	28	53	1239.586
#129	ZNF71	25	18	43	703.373
#130	ERF	25	23	48	1078.334
#131	TBX15	25	26	51	993.359
#132	FOXA1	25	26	51	580.695
#133	OVOL1	25	19	44	2321.773
#134	ATF2	25	28	53	1370.936
#135	WNT5A	25	22	47	713.114
#136	TADA2A	25	21	46	1449.723
#137	NR4A3	25	17	42	321.023
#138	PLAG1	25	19	44	596.862
#139	RFX3	25	25	50	1242.124
#140	ZNF92	25	21	46	723.564
#141	HOXA2	25	8	33	148.487
#142	HOXD4	25	15	40	737.609
#143	ESRRG	25	26	51	1006.96
#144	POU6F1	25	27	52	1161.662
#145	NR5A2	25	22	47	1137.573
#146	HOXD10	24	11	35	221.413
#147	FOS	24	8	32	237.051
#148	SOX15	24	19	43	1435.427
#149	TBX10	24	18	42	505.424
#150	SATB1	24	13	37	443.182
#151	ZFP37	24	27	51	1859.32
#152	SALL1	24	23	47	795.263
#153	SOX17	24	19	43	1065.94
#154	SP3	24	22	46	1421.452
#155	PPARA	24	21	45	1101.168
#156	NPAT	23	26	49	2137.655
#157	DLX2	23	25	48	1539.282
#158	TP53	23	26	49	1515.632
#159	THRB	23	23	46	3017.989
#160	RARA	23	18	41	585.943
#161	NFIC	23	18	41	691.995
#162	CITED1	23	18	41	368.631
#163	MEOX1	23	16	39	416.92
#164	RUNX1T1	23	23	46	902.698
#165	HOXA13	23	14	37	386.45
#166	ZNF207	23	21	44	2201.917
#167	HOXD11	23	13	36	382.68
#168	CSRNP3	23	24	47	1095.107
#169	MECOM	23	21	44	696.264
#170	SOX6	23	23	46	754.066
#171	BACH2	23	21	44	422.509
#172	MSX2	23	29	52	1797.578
#173	HOXD9	22	18	40	916.322
#174	EGR1	22	18	40	489.059
#175	POU2F3	22	18	40	643.019
#176	SPI1	22	21	43	649.797
#177	GATA4	22	23	45	918.568
#178	NEUROD1	22	23	45	1245.12
#179	TSHZ2	22	24	46	471.006
#180	FOXK1	22	26	48	1389.063
#181	BCL3	22	25	47	515.376
#182	ZNF117	22	28	50	1171.065
#183	SPIB	22	16	38	446.663
#184	HES5	22	21	43	992.147
#185	SOX8	22	22	44	470.941
#186	REL	22	20	42	926.692
#187	ZNF496	22	22	44	844.15
#188	GCM1	22	21	43	1031.374
#189	POU3F2	22	17	39	1497.563
#190	BARX1	22	22	44	936.214
#191	HCFC1	22	18	40	358.08
#192	ELF5	22	26	48	1002.659
#193	MKX	22	29	51	1676.811
#194	IRX1	22	20	42	1255.445
#195	HOXC11	21	19	40	628.923
#196	NKX2-8	21	24	45	1113.075
#197	MEIS3	21	24	45	983.263
#198	GATA3	21	18	39	761.404
#199	HIF3A	21	25	46	1206.39
#200	BLZF1	21	25	46	978.957
#201	ZNF483	21	30	51	1276.933
#202	SIX2	21	22	43	1099.96
#203	ARNT	21	22	43	1317.118
#204	ETV6	21	14	35	393.597
#205	RORC	21	18	39	542.185
#206	ZNF81	21	23	44	1023.81
#207	MESP2	21	20	41	834.184
#208	DMRT2	21	21	42	913.886
#209	TFAP2C	20	27	47	848.288
#210	HNF1B	20	20	40	318.004
#211	ZNF33B	20	22	42	1223.752
#212	ZNF93	20	28	48	1701.582
#213	MITF	20	27	47	1329.014
#214	HOXB1	20	26	46	895.797
#215	ZNF155	20	27	47	1179.309
#216	HNF4A	20	23	43	858.845
#217	PITX2	20	19	39	778.86
#218	ENO1	20	17	37	412.622
#219	SOX2	20	26	46	977.566
#220	MAFG	20	19	39	526.382
#221	AR	20	21	41	1329.654
#222	HOXB8	20	16	36	343.608
#223	ST18	20	24	44	1012.838
#224	TFE3	20	26	46	826.649
#225	ARNT2	20	29	49	1630.936
#226	HOXC10	20	21	41	690.073
#227	SOX18	20	20	40	377.006
#228	THRA	20	24	44	632.32
#229	TLX2	20	28	48	749.535
#230	GATAD2A	19	26	45	876.29
#231	SCAND2	19	25	44	1677.695
#232	KLF12	19	21	40	900.545
#233	ZNF135	19	23	42	629.564
#234	HIC1	19	31	50	1571.8
#235	MEOX2	19	19	38	526.858
#236	SIX6	19	27	46	1060.371
#237	C12orf28	19	24	43	740.538
#238	ZNF70	19	23	42	760.74
#239	NFE2	19	19	38	481.466
#240	PAX4	19	25	44	1087.578
#241	C2orf3	19	28	47	885.63
#242	CDKN2A	19	23	42	808.834
#243	EN2	19	27	46	1011.263
#244	ZNF192	19	24	43	736.291
#245	RXRG	19	18	37	601.547
#246	SNAPC5	19	21	40	1508.401
#247	ZNF167	19	26	45	909.432
#248	KLF9	19	23	42	796.151
#249	TBX2	18	18	36	306.464
#250	FOXI1	18	26	44	1267.487
#251	POU1F1	18	29	47	1261.62
#252	RFXAP	18	21	39	661.151
#253	NR2E3	18	26	44	1173.824
#254	ZFHX2	18	25	43	1205.853
#255	PBX1	18	29	47	1265.102
#256	PKNOX2	18	24	42	1019.734
#257	HOXB13	18	24	42	679.443
#258	FOXE1	18	31	49	1477.682
#259	SNAI3	18	23	41	832.85
#260	RORB	18	22	40	618.115
#261	TGIF2LY	18	21	39	906.915
#262	MYCN	18	18	36	450.267
#263	TP73	18	30	48	1382.726
#264	HOXA1	18	16	34	252.67
#265	TADA3	18	28	46	1351.112
#266	FOXN4	18	20	38	831.691
#267	STAT5B	18	24	42	691.092
#268	TEAD1	18	25	43	1105.862
#269	PDX1	18	22	40	775.529
#270	ZSCAN2	18	29	47	902.472
#271	IRX3	18	33	51	585.184
#272	MLLT10	18	21	39	701.174
#273	HOXB9	17	20	37	348.209
#274	TBR1	17	24	41	725.956
#275	BNC1	17	28	45	885.995
#276	MYT1	17	26	43	709.352
#277	ATF3	17	14	31	206.462
#278	HOXC5	17	20	37	351.089
#279	ALX4	17	24	41	686.376
#280	SUPT6H	17	26	43	812.101
#281	DLX4	17	28	45	1287.901
#282	IRX4	17	20	37	874.343
#283	ATF7	17	21	38	566.632
#284	HESX1	17	19	36	397.611
#285	NR1I3	17	26	43	983.026
#286	ZIC5	17	17	34	258.24
#287	CREBZF	17	19	36	773.846
#288	NFATC2	17	30	47	1341.9
#289	FOXH1	17	31	48	1187.017
#290	SIX1	17	22	39	688.979
#291	NOBOX	16	22	38	642.258
#292	ZNF90	16	26	42	944.909
#293	ETV1	16	29	45	720.067
#294	TFAP2D	16	26	42	2354.355
#295	LZTS1	16	26	42	689.471
#296	ZIC3	16	25	41	679.436
#297	POU3F1	16	24	40	1124.214
#298	DLX3	16	22	38	468.214
#299	ESX1	16	21	37	1222.463
#300	BCL11B	16	21	37	781.116
#301	ARX	16	38	54	874.137
#302	LMX1A	16	23	39	962
#303	ESR2	16	20	36	2675.753
#304	ZNF134	16	22	38	456.146
#305	FOSB	16	5	21	39.74
#306	VENTX	16	28	44	1245.179
#307	CTBP1	16	26	42	679.491
#308	ESRRB	16	22	38	663.36
#309	PAX7	16	26	42	984.578
#310	MGA	16	24	40	751.283
#311	TBX20	16	22	38	714.448
#312	MIXL1	16	22	38	834.632
#313	HMGA2	16	28	44	953.168
#314	GATA5	16	20	36	851.636
#315	ETV7	16	19	35	882.601
#316	SMAD2	16	24	40	745.114
#317	ZNF396	15	18	33	1322.346
#318	TBX22	15	26	41	740.476
#319	TRIM29	15	24	39	1090.281
#320	ZNF157	15	21	36	575.558
#321	L3MBTL4	15	32	47	987.591
#322	IKZF3	15	29	44	916.335
#323	CREB5	15	31	46	594.646
#324	NEUROG1	15	25	40	3880.119
#325	CUX2	15	28	43	1785.647
#326	GRHL3	15	26	41	989.956
#327	GSX2	15	21	36	1031.507
#328	SOX21	15	20	35	683.632
#329	PBX3	15	26	41	1205.649
#330	CREB3L3	15	27	42	741.996
#331	EN1	15	22	37	878.002
#332	TSC22D3	15	27	42	1036.687
#333	HMG20B	15	29	44	1290.154
#334	ASCL1	14	20	34	549.001
#335	HDX	14	24	38	1084.153
#336	LASS5	14	25	39	690.893
#337	NKX6-2	14	25	39	639.834
#338	ZNF85	14	24	38	751.32
#339	GBX2	14	23	37	528.656
#340	ZNF287	14	22	36	748.884
#341	FOXR2	14	23	37	630.352
#342	PGR	14	24	38	671.262
#343	ZNF154	14	25	39	719.646
#344	JUND	14	24	38	1159.17
#345	LHX4	14	26	40	828.246
#346	ISL2	14	25	39	359.738
#347	SOX30	14	30	44	789.915
#348	NKX2-1	14	30	44	744.089
#349	RARB	14	27	41	629.046
#350	CSDA	14	23	37	396.163
#351	ELK4	14	30	44	1076.466
#352	MYT1L	14	31	45	1056.227
#353	GSX1	14	22	36	736.865
#354	NFIA	14	23	37	629.057
#355	GSC2	14	25	39	681.712
#356	IRX5	14	20	34	463.028
#357	TLX1	14	24	38	706.825
#358	FOXP2	14	29	43	403.125
#359	DLX6	13	28	41	567.247
#360	IRX2	13	34	47	2409.893
#361	OTX1	13	26	39	695.079
#362	HOXD1	13	24	37	838.712
#363	HNRNPAB	13	22	35	494.98
#364	TFAP2B	13	23	36	477.252
#365	FOXP3	13	26	39	777.532
#366	NCOR1	13	29	42	843.995
#367	RXRB	13	29	42	966.779
#368	HOXC12	13	22	35	448.382
#369	ZNF215	13	25	38	661.437
#370	FOXD3	13	28	41	1136.277
#371	ZSCAN10	13	26	39	720.002
#372	LHX9	13	29	42	636.341
#373	HSF4	13	21	34	375.43
#374	RUNX2	13	28	41	726.348
#375	ZNF80	13	26	39	781.819
#376	PLSCR1	13	23	36	626.782
#377	TAL1	13	29	42	1024.325
#378	PAX3	13	30	43	883.048
#379	KLF15	13	25	38	449.838
#380	DMRT1	12	25	37	511.383
#381	SOX4	12	25	37	674.536
#382	KLF17	12	28	40	1062.32
#383	GAS7	12	27	39	753.478
#384	MYNN	12	23	35	652.597
#385	TCF20	12	24	36	815.219
#386	KDM5B	12	28	40	676.738
#387	RUNX1	12	35	47	734.99
#388	VSX1	12	28	40	620.585
#389	LHX2	12	33	45	1203.627
#390	NANOGNB	12	24	36	1005.383
#391	ALS2CR8	12	31	43	688.619
#392	OLIG2	12	28	40	1501.569
#393	POU4F2	12	25	37	753.414
#394	PPARD	12	24	36	476.145
#395	NFIB	12	26	38	782.726
#396	ONECUT1	12	25	37	798.255
#397	SRY	12	20	32	444.573
#398	RCAN1	12	26	38	726.916
#399	FOXJ2	12	23	35	640.184
#400	CLOCK	12	21	33	733.664
#401	TULP4	11	29	40	1227.352
#402	FUBP1	11	26	37	575.684
#403	POU4F3	11	27	38	1337.823
#404	E2F2	11	34	45	677.63
#405	ZNF131	11	23	34	1182.431
#406	TEF	11	26	37	737.76
#407	MYF6	11	23	34	697.8
#408	ZIC1	11	22	33	417.401
#409	ERG	11	23	34	531.751
#410	RORA	11	21	32	427.276
#411	GATAD1	11	35	46	825.899
#412	EMX1	11	24	35	446.862
#413	FLI1	11	29	40	573.011
#414	TBX3	11	28	39	1442.633
#415	BRD8	11	25	36	604.974
#416	MAF	11	29	40	390.385
#417	SP140	11	22	33	564.079
#418	AFF4	11	20	31	412.048
#419	POU5F2	11	29	40	892.207
#420	SOX11	11	22	33	460.89
#421	SOX5	11	29	40	856.123
#422	HOXD13	11	27	38	844.407
#423	RELA	11	24	35	373.681
#424	ZSCAN23	11	25	36	748.264
#425	NRL	11	22	33	497.364
#426	PURA	11	21	32	637.512
#427	EPAS1	11	28	39	567.417
#428	SMAD4	11	33	44	1042.433
#429	FOXO1	11	25	36	662.256
#430	ARNTL2	10	25	35	373.989
#431	PAX6	10	23	33	678.728
#432	GLI2	10	22	32	493.38
#433	SMAD6	10	30	40	892.986
#434	HIRA	10	24	34	698.072
#435	NFATC1	10	20	30	461.111
#436	NR1H4	10	34	44	941.076
#437	LHX8	10	28	38	863.977
#438	MYF5	10	23	33	542.116
#439	TFDP3	10	22	32	509.579
#440	PRDM2	10	23	33	537.808
#441	NR2E1	10	23	33	465.342
#442	ZSCAN20	10	25	35	1549.993
#443	POU3F3	10	30	40	568.172
#444	NPAS1	10	31	41	514.537
#445	SCAND3	10	36	46	748.52
#446	SLC2A4RG	10	20	30	790.552
#447	ZFHX4	10	27	37	752.931
#448	TCF25	10	26	36	599.467
#449	SIX3	9	34	43	829.711
#450	DMBX1	9	30	39	700.013
#451	SIX4	9	28	37	515.901
#452	SIN3A	9	24	33	674.016
#453	SP4	9	26	35	404.744
#454	HSF5	9	29	38	543.075
#455	VTN	9	25	34	499.48
#456	SPIC	9	28	37	780.498
#457	RARG	9	25	34	559.428
#458	ANKRD30A	9	22	31	410.111
#459	NFKB2	9	23	32	586.267
#460	CBL	9	26	35	486.282
#461	ZNF132	9	25	34	453.5
#462	PAX8	9	31	40	783.168
#463	LMX1B	9	29	38	602.46
#464	ZSCAN1	8	32	40	365.665
#465	TBX1	8	27	35	600.569
#466	DLX1	8	28	36	542.32
#467	MLL	8	29	37	449.935
#468	WT1	8	36	44	563.286
#469	NOTCH1	8	30	38	396.755
#470	SEBOX	8	23	31	295.408
#471	REST	8	23	31	362.444
#472	MLX	8	30	38	550.932
#473	POU2F1	8	24	32	441.635
#474	ZSCAN4	8	39	47	501.047
#475	OTX2	8	30	38	1379.064
#476	TLX3	8	32	40	361.396
#477	NR0B1	8	27	35	531.212
#478	FOXG1	8	28	36	570.446
#479	ZNF175	8	20	28	371.466
#480	HLF	8	21	29	369.38
#481	POU6F2	8	30	38	351.354
#482	ZSCAN12	8	26	34	375.059
#483	ZNF397	7	25	32	282.506
#484	PTH	7	29	36	730.66
#485	TBX5	7	31	38	402.194
#486	NEUROD2	7	28	35	440.157
#487	ZFP36L1	7	26	33	339.304
#488	BHLHE41	7	29	36	336.174
#489	SIM1	7	35	42	543.621
#490	RERE	7	29	36	374.747
#491	FOXL2	7	29	36	519.88
#492	ELK1	6	29	35	1507.534
#493	GLI3	6	26	32	495.511
#494	ZFP42	5	26	31	303.498
#495	SIM2	5	25	30	350.305
#496	EGR4	5	29	34	233.901
#497	PHOX2B	5	29	34	527.823
#498	ZKSCAN3	5	34	39	415.309
#499	NFYA	5	26	31	220.1
#500	IRF4	3	31	34	214.649