Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MEF2C	57	5	62	849.028
#2	ZFPM2	56	8	64	246.186
#3	ZEB1	56	1	57	11.99
#4	EBF1	56	7	63	2303.435
#5	ETS1	51	11	62	1097.284
#6	ZEB2	49	9	58	449.958
#7	NR3C1	48	4	52	801.552
#8	MAFB	46	2	48	23.467
#9	RUNX1T1	44	6	50	277.046
#10	MEIS2	43	7	50	170.282
#11	HMGA1	42	8	50	938.925
#12	NR1I2	42	7	49	616.685
#13	NKX2-3	42	8	50	3168.827
#14	MEOX1	41	15	56	659.966
#15	HOXB2	40	14	54	1068.614
#16	NR3C2	38	8	46	560.383
#17	ETV4	38	13	51	1028.667
#18	BCL3	37	9	46	1199.75
#19	ZNF165	37	11	48	1013.006
#20	SATB2	37	6	43	311.88
#21	HEY1	36	11	47	1268.99
#22	NR2F6	36	10	46	455.198
#23	TFCP2L1	36	10	46	579.57
#24	TCF21	35	7	42	384.318
#25	CDX2	35	11	46	333.329
#26	STRN3	35	9	44	1493.447
#27	ZGLP1	35	10	45	565.499
#28	NPAS2	35	15	50	1500.026
#29	RARA	34	13	47	586.594
#30	MEIS1	34	15	49	234.612
#31	HIC1	34	11	45	427.233
#32	PLAG1	34	11	45	1102.792
#33	ATOH1	34	10	44	782.299
#34	FOSL2	33	10	43	682.893
#35	PROX1	33	10	43	1100.323
#36	AEBP1	32	6	38	214.902
#37	TCF7	32	14	46	420.766
#38	CREB3L1	32	7	39	359.509
#39	HOPX	32	7	39	132.92
#40	MTA2	32	9	41	902.211
#41	TFAP2A	31	14	45	827.465
#42	PITX2	31	17	48	1181.581
#43	HNF4G	31	11	42	649.028
#44	C11orf9	31	10	41	1329.834
#45	OVOL1	31	17	48	850.867
#46	MEOX2	30	15	45	195.624
#47	MMP14	30	11	41	749.654
#48	TWIST1	30	11	41	928.044
#49	USF1	30	10	40	673.185
#50	ELF4	30	13	43	997.725
#51	MBD1	30	16	46	1426.379
#52	SPIB	30	17	47	1115.769
#53	ISX	30	12	42	306.343
#54	LHX6	30	8	38	769.799
#55	TRIM22	29	12	41	1070.756
#56	ZNF193	29	15	44	1009.736
#57	HOXC11	29	17	46	2429.605
#58	HOXC10	29	14	43	1425.347
#59	STAT1	29	10	39	251.331
#60	SREBF1	29	13	42	774.898
#61	TSC22D2	29	12	41	1011.121
#62	SIX4	28	16	44	845.183
#63	HOXB6	28	10	38	939.922
#64	SUPT6H	28	11	39	895.071
#65	NR4A3	28	16	44	1946.352
#66	SMAD3	28	16	44	2720.815
#67	TRPS1	28	15	43	727.123
#68	ETV6	27	16	43	810.653
#69	SPDEF	27	10	37	443.448
#70	ZNF174	27	18	45	1186.405
#71	ARNTL2	27	19	46	770.576
#72	NR5A2	27	14	41	1621.924
#73	HOXD13	27	13	40	814.351
#74	BARHL1	26	15	41	1076.168
#75	FOXA2	26	13	39	814.346
#76	RUNX1	26	19	45	1656.938
#77	FOXP2	26	21	47	1016.306
#78	EHF	26	16	42	996.549
#79	PRRX1	26	6	32	56.039
#80	MYC	26	18	44	1533.189
#81	HOXD10	25	10	35	595.1
#82	SPI1	25	9	34	902.769
#83	ZNF256	25	13	38	739.359
#84	PGR	25	15	40	763.328
#85	HOXC9	25	13	38	996.365
#86	SIX5	24	15	39	1014.304
#87	KDM5B	24	19	43	1380.897
#88	ZNF175	24	15	39	1143.222
#89	TFDP1	24	15	39	1081.434
#90	MXD1	24	20	44	947.412
#91	FOXD1	24	22	46	805.411
#92	THRB	24	15	39	754.798
#93	ZNF71	24	11	35	659.612
#94	TLX3	23	15	38	870.02
#95	NFIC	23	17	40	1100.114
#96	AHCTF1	23	19	42	1163.953
#97	NFKB2	23	18	41	1278.135
#98	SNAI3	23	13	36	745.323
#99	RFX3	23	14	37	921.646
#100	SALL1	23	11	34	347.554
#101	FOXL1	23	16	39	743.757
#102	SIX6	23	15	38	1714.466
#103	ELF5	23	23	46	1413.983
#104	HAND1	23	12	35	711.512
#105	ZNF444	23	12	35	959.662
#106	SLC26A3	23	23	46	1007.308
#107	NFX1	23	13	36	1161.296
#108	NFATC1	22	17	39	1242.466
#109	PAX5	22	13	35	714.508
#110	NEUROD2	22	17	39	1076.425
#111	HOXA9	22	9	31	474.38
#112	TRIM29	22	25	47	1938.53
#113	FOS	22	10	32	409.859
#114	HOXB8	22	12	34	372.532
#115	ETS2	22	19	41	1338.87
#116	ZNF154	21	15	36	1158.277
#117	HES5	21	18	39	916.68
#118	TCF12	21	13	34	815.014
#119	HOXD11	21	11	32	804.367
#120	PCGF2	21	17	38	1046.221
#121	ZNF449	21	12	33	881.489
#122	GATA5	21	18	39	1531.726
#123	ZIC5	21	17	38	822.77
#124	NPAT	21	16	37	836.44
#125	FOSL1	21	23	44	1297.285
#126	KLF15	21	20	41	662.091
#127	TAF13	21	15	36	1401.214
#128	NKX3-2	21	23	44	1629.73
#129	GLIS3	21	19	40	481.737
#130	HNF4A	21	17	38	853.138
#131	ISL1	21	18	39	855.478
#132	BCL6	21	24	45	1891.402
#133	STAT5B	20	19	39	690.364
#134	ATF5	20	14	34	803.92
#135	CEBPE	20	17	37	899.407
#136	ESRRB	20	25	45	1683.337
#137	GAS7	20	17	37	474.559
#138	MZF1	20	20	40	1134.599
#139	PAX6	20	21	41	1222.961
#140	HEY2	20	14	34	420.408
#141	TBX22	20	15	35	653.168
#142	C12orf28	20	21	41	1473.085
#143	CREM	20	16	36	1098.727
#144	TRERF1	20	9	29	655.074
#145	EGR1	20	14	34	295.976
#146	SOX6	20	25	45	1386.039
#147	PDX1	20	17	37	979.104
#148	SOX10	20	11	31	643.232
#149	SOX30	20	21	41	1014.047
#150	PGBD1	20	18	38	993.09
#151	RXRB	19	15	34	929.407
#152	ZSCAN1	19	19	38	1052.817
#153	DMRT1	19	17	36	1138.914
#154	ZNF85	19	19	38	1075.012
#155	ISL2	19	19	38	1096.04
#156	TSHZ2	19	18	37	289.517
#157	HSF1	19	20	39	1129.662
#158	TFEC	19	15	34	754.511
#159	KLF2	19	15	34	844.6
#160	ARNT2	19	23	42	936.775
#161	SMAD2	19	20	39	1097.224
#162	RELA	19	15	34	1164.035
#163	ZXDC	19	17	36	1094.612
#164	VENTX	19	14	33	764.917
#165	HOXC8	18	22	40	1660.057
#166	KCNH8	18	16	34	689.575
#167	ESX1	18	18	36	1113.355
#168	LHX1	18	18	36	964.691
#169	ZSCAN18	18	18	36	1417.549
#170	GCM1	18	21	39	1117.616
#171	PBX1	18	19	37	1517.342
#172	SOX1	18	19	37	1244.814
#173	PKNOX2	18	16	34	991.942
#174	POU6F2	18	20	38	1038.882
#175	FOXQ1	18	17	35	964.704
#176	TP73	18	15	33	796.408
#177	GATA2	18	18	36	1143.34
#178	PAX4	18	15	33	861.423
#179	HOXA5	18	11	29	536.089
#180	POU3F2	18	19	37	1189.069
#181	HNRNPAB	18	12	30	594.145
#182	KDM5A	18	14	32	770.163
#183	CSRNP3	18	18	36	791.2
#184	TAL1	18	18	36	934.572
#185	SLC2A4RG	17	18	35	929.37
#186	SCAND1	17	15	32	804.394
#187	ETV5	17	25	42	991.334
#188	TBR1	17	14	31	721.49
#189	GSX2	17	17	34	923.515
#190	VAX2	17	19	36	1023.898
#191	PPARA	17	17	34	917.286
#192	TP53	17	11	28	437.94
#193	ZNF396	17	24	41	1356.307
#194	TCF3	17	16	33	717.039
#195	ZFHX3	17	21	38	854.362
#196	SIX1	17	15	32	989.776
#197	SOX4	17	14	31	853.3
#198	GLI2	17	20	37	1098.538
#199	FOSB	17	14	31	456.131
#200	ZBTB38	17	13	30	515.422
#201	NFIX	17	15	32	974.122
#202	CDKN2A	17	20	37	971.054
#203	IRX1	17	14	31	999.614
#204	ZNF41	17	16	33	1033.431
#205	HOXA13	17	14	31	789.888
#206	KLF1	17	16	33	932.351
#207	NPAS1	17	17	34	1168.299
#208	NRL	17	21	38	955.941
#209	PHF1	17	16	33	900.072
#210	TRIM25	17	18	35	797.844
#211	IRX5	17	18	35	1240.534
#212	TWIST2	17	16	33	838.824
#213	POU2F3	17	15	32	943.64
#214	SCAND2	17	22	39	1038.249
#215	RERE	17	17	34	889.863
#216	TULP4	16	13	29	459.764
#217	NR4A1	16	8	24	343.24
#218	FOXC1	16	17	33	760.047
#219	PKNOX1	16	20	36	1048.721
#220	IKZF1	16	23	39	1501.997
#221	CREB5	16	25	41	1191
#222	IRX3	16	18	34	946.94
#223	MLX	16	17	33	790.033
#224	SIM2	16	17	33	949.865
#225	SCAND3	16	23	39	1125.742
#226	SOX11	16	19	35	818.343
#227	NFATC4	16	17	33	835.019
#228	MSC	16	18	34	1323.309
#229	E2F2	16	17	33	687.548
#230	HCFC1	16	19	35	940.938
#231	GLI3	16	19	35	820.597
#232	HR	16	16	32	610.79
#233	FLI1	16	18	34	1144.639
#234	YY1	16	15	31	473.698
#235	ZNF83	16	16	32	749.38
#236	GATA1	16	15	31	624.038
#237	TADA2A	16	20	36	784.586
#238	TCF7L2	16	16	32	1323.077
#239	NFYC	16	21	37	1197.845
#240	VDR	16	17	33	809.476
#241	RORC	16	23	39	863.061
#242	NANOG	16	22	38	883.876
#243	ZNF134	16	24	40	1096.941
#244	ZNF397	16	15	31	771.674
#245	FOXD3	15	16	31	526.591
#246	ASCL2	15	23	38	608.34
#247	ARX	15	14	29	505.424
#248	FOXG1	15	18	33	1119.777
#249	MGA	15	22	37	734.228
#250	NFIB	15	25	40	979.859
#251	RFXAP	15	17	32	499.336
#252	HOXD3	15	14	29	704.874
#253	HLF	15	16	31	696.812
#254	IRF4	15	17	32	954.646
#255	HOXD1	15	18	33	753.29
#256	CITED1	15	22	37	995.469
#257	ETV1	15	15	30	589.595
#258	TEAD2	15	17	32	800.863
#259	TFAP2B	15	23	38	965.115
#260	HES6	15	17	32	695.605
#261	TBX6	15	21	36	837.058
#262	NKX2-1	15	15	30	868.81
#263	PITX1	15	16	31	645.819
#264	ZNF24	15	22	37	760.519
#265	FOXJ1	15	21	36	929.322
#266	GATA4	15	15	30	2458.05
#267	FOXO3	15	26	41	969.492
#268	LEF1	15	17	32	724.216
#269	PHOX2B	15	22	37	636.917
#270	KLF9	15	18	33	808.741
#271	EPAS1	15	19	34	822.287
#272	TBX20	15	19	34	3348.921
#273	BRD8	15	16	31	929.936
#274	CUX2	15	23	38	1084.448
#275	ZNF500	15	25	40	1006.377
#276	ARNT	15	16	31	837.439
#277	CSDA	15	16	31	837.337
#278	BACH2	15	17	32	633.797
#279	POU3F1	15	17	32	642.417
#280	TSC22D3	15	18	33	904.033
#281	NEUROG1	15	14	29	587.751
#282	CTBP1	15	18	33	1086.406
#283	CEBPD	15	18	33	973.045
#284	BARX1	15	16	31	849.687
#285	LASS5	15	15	30	1094.449
#286	EMX1	15	15	30	867.568
#287	ZNF155	14	14	28	687.242
#288	ZNF135	14	16	30	260.28
#289	DMRT2	14	19	33	1304.05
#290	ZNF207	14	19	33	1470.509
#291	ZFP42	14	20	34	807.734
#292	ESRRG	14	15	29	631.651
#293	SMAD9	14	21	35	860.399
#294	HOXA1	14	19	33	1214.741
#295	FOXI1	14	15	29	659.334
#296	RUNX3	14	22	36	1011.8
#297	DLX3	14	16	30	649.83
#298	MYF6	14	20	34	575.338
#299	HOXB13	14	25	39	1181.561
#300	ZBTB17	14	20	34	896.12
#301	HMGA2	14	16	30	686.303
#302	ERG	14	16	30	799.437
#303	MAF	14	23	37	695.69
#304	NFYA	14	21	35	1114.807
#305	CREB3L3	14	19	33	870.063
#306	SCRT1	14	20	34	1253.388
#307	IRX2	14	31	45	1157.017
#308	BHLHE41	14	21	35	648.057
#309	SMAD6	14	20	34	1654.387
#310	ESR1	14	18	32	1065.74
#311	FOXK2	14	20	34	844.682
#312	SPEN	14	19	33	1117.073
#313	MYNN	14	16	30	654.621
#314	RCOR1	14	12	26	448.337
#315	TAF4	14	14	28	470.356
#316	GRHL3	14	24	38	1263.206
#317	OLIG2	14	18	32	1207.199
#318	HOXD9	13	19	32	633.125
#319	NEUROD1	13	20	33	1003.155
#320	PLSCR1	13	24	37	890.47
#321	TLX2	13	20	33	1532.977
#322	PAX7	13	21	34	1060.75
#323	HOXA3	13	13	26	581.929
#324	VSX1	13	18	31	937.524
#325	LMO4	13	22	35	804.831
#326	NR2E3	13	22	35	1027.471
#327	MYT1L	13	26	39	916.525
#328	ANKRD30A	13	22	35	877.272
#329	SMAD4	13	16	29	719.649
#330	JUND	13	21	34	1203.568
#331	PPBPL2	13	19	32	958.092
#332	NFIA	13	12	25	318.102
#333	BATF	13	16	29	691.188
#334	PTH	13	17	30	809.168
#335	ALX4	13	24	37	765.349
#336	L3MBTL4	13	19	32	927.032
#337	RARG	13	22	35	887.807
#338	TBX15	13	19	32	785.458
#339	PBX3	13	18	31	856.858
#340	ZIC1	13	20	33	733.551
#341	POU3F3	13	21	34	1253.454
#342	HOXA2	13	19	32	557.581
#343	FOXO1	13	12	25	689.366
#344	HOXA4	13	18	31	712.801
#345	ONECUT2	13	22	35	1071.872
#346	POU2F1	13	24	37	794.841
#347	MYCL1	13	19	32	603.851
#348	MESP1	13	16	29	476.576
#349	LHX2	13	19	32	702.641
#350	MITF	13	16	29	535.504
#351	BCL11B	12	14	26	436.871
#352	NKX2-8	12	17	29	515.928
#353	PHOX2A	12	17	29	569.496
#354	ZIC3	12	13	25	454.007
#355	ZNF33B	12	20	32	856
#356	ZNF496	12	17	29	551.957
#357	MYCN	12	27	39	911.958
#358	TFE3	12	21	33	1106.884
#359	GATAD1	12	20	32	776.526
#360	MYT1	12	19	31	971.051
#361	FOXA1	12	28	40	943.197
#362	C2orf3	12	19	31	572.397
#363	RUNX2	12	22	34	723.058
#364	SIM1	12	26	38	1020.522
#365	NR5A1	12	15	27	597.301
#366	FOXB1	12	16	28	611.534
#367	NFE2	12	22	34	724.422
#368	NR0B1	12	18	30	775.388
#369	REST	12	15	27	620.483
#370	GSX1	12	14	26	406.3
#371	DLX1	12	13	25	575.797
#372	RARB	12	23	35	739.661
#373	HIF3A	12	26	38	827.473
#374	ZNF19	12	15	27	530.944
#375	ZNF287	12	18	30	773.068
#376	TEF	12	25	37	927.544
#377	SIX3	12	21	33	734.238
#378	PEG3	12	20	32	396.219
#379	MSRB2	12	19	31	763.563
#380	BNC1	12	26	38	752.289
#381	FOXO6	12	18	30	451.176
#382	HOXA11	12	15	27	1043.085
#383	ZNF215	11	24	35	1018.452
#384	GATAD2A	11	22	33	835.197
#385	ZNF90	11	21	32	1016.947
#386	SPIC	11	22	33	821.278
#387	GBX2	11	19	30	680.798
#388	SNAPC5	11	20	31	576.766
#389	ZNF93	11	20	31	868.814
#390	ELK1	11	19	30	739.932
#391	CRX	11	16	27	542.599
#392	POU2F2	11	16	27	437.388
#393	FOXL2	11	19	30	599.677
#394	DMBX1	11	21	32	895.725
#395	PURB	11	19	30	509.131
#396	NR1I3	11	15	26	585.876
#397	ERF	11	19	30	619.729
#398	TBX19	11	20	31	868.915
#399	THRA	11	22	33	904.295
#400	ZSCAN12	11	17	28	585.261
#401	ZKSCAN3	11	13	24	514.626
#402	CREBBP	11	22	33	668.566
#403	KLF12	11	21	32	710.037
#404	BACH1	11	19	30	532.465
#405	TBX3	11	19	30	776.899
#406	ENO1	11	18	29	628.928
#407	ST18	11	16	27	501.788
#408	EVX1	11	18	29	478.101
#409	FOXH1	11	22	33	857.791
#410	BLZF1	11	22	33	757.931
#411	ZSCAN4	11	12	23	695.861
#412	ASCL1	11	23	34	858.892
#413	ZNF446	11	18	29	774.073
#414	ATF6B	11	11	22	249.828
#415	MLXIPL	11	16	27	483.051
#416	EN2	11	24	35	753.74
#417	NCOR1	10	23	33	675.045
#418	NOBOX	10	19	29	477.688
#419	TP63	10	19	29	664.476
#420	POU1F1	10	23	33	759.27
#421	SOX5	10	21	31	501.641
#422	SOX8	10	23	33	792.625
#423	RCAN1	10	19	29	539.745
#424	KLF16	10	26	36	651.13
#425	DLX6	10	25	35	756.223
#426	CREBZF	10	22	32	746.862
#427	ELK4	10	25	35	673.443
#428	NR1H4	10	28	38	623.013
#429	MSX2	10	21	31	586.185
#430	PRDM2	10	22	32	611.331
#431	HOXD4	10	14	24	441.464
#432	FOXS1	10	17	27	589.582
#433	NFATC2	10	25	35	728.621
#434	ZNF81	10	18	28	534.338
#435	ZNF483	10	17	27	400.469
#436	WT1	9	26	35	802.844
#437	SOX2	9	30	39	731.737
#438	ZNF157	9	23	32	786.388
#439	ZFHX4	9	21	30	582.042
#440	ONECUT1	9	19	28	572.774
#441	TFAP2C	9	17	26	459.083
#442	FOXP3	9	20	29	413.523
#443	EGR4	9	21	30	542.441
#444	ZSCAN20	9	21	30	461.776
#445	GATAD2B	9	19	28	912.302
#446	ZNF132	9	17	26	559.269
#447	DLX2	9	23	32	676.448
#448	OTX2	9	25	34	933.072
#449	NKX6-2	9	21	30	657.27
#450	POU4F1	9	18	27	611.616
#451	ZFP36L1	8	17	25	790.087
#452	HMG20B	8	17	25	537.883
#453	MAFK	8	16	24	302.169
#454	ZFHX2	8	21	29	569.905
#455	IRX4	8	24	32	674.076
#456	ESR2	8	22	30	701.205
#457	MYF5	8	25	33	1044.46
#458	HESX1	8	23	31	689.302
#459	RORB	8	22	30	622.093
#460	MECOM	8	19	27	549.779
#461	HIRA	8	25	33	992.758
#462	PPARD	8	21	29	751.862
#463	FOXN4	8	23	31	682.603
#464	FOXE1	8	29	37	909.241
#465	TSC22D1	8	23	31	686.058
#466	HSF5	8	19	27	518.031
#467	ZNF167	8	25	33	317.791
#468	MIXL1	8	20	28	790.944
#469	RORA	8	24	32	661.82
#470	ALS2CR8	8	17	25	438.14
#471	ZSCAN23	7	28	35	768.351
#472	POU6F1	7	21	28	447.739
#473	ATF2	7	17	24	342.891
#474	SP140	7	17	24	338.93
#475	LHX8	7	21	28	519.442
#476	GATA3	7	23	30	493.121
#477	LMX1A	7	19	26	479.865
#478	IKZF3	7	22	29	367.727
#479	LZTS1	7	22	29	559.238
#480	TADA3	7	21	28	478.813
#481	SIN3A	7	18	25	432.525
#482	ZIC2	6	35	41	483.245
#483	SOX21	6	23	29	459.645
#484	MLLT10	6	29	35	701.821
#485	MLL	6	18	24	752.677
#486	MKX	6	20	26	333.332
#487	TBX1	6	19	25	497.488
#488	TBX5	6	16	22	238.446
#489	HMGB2	6	22	28	440.344
#490	LHX9	5	22	27	310.352
#491	PAX8	5	24	29	280.699
#492	GSC2	5	14	19	166.484
#493	AFF4	5	20	25	329.494
#494	ZNF3	5	22	27	304.606
#495	ZNF80	5	26	31	412.511
#496	RAX2	5	23	28	375.871
#497	TBX2	5	20	25	262.792
#498	ZNF131	5	23	28	372.49
#499	PAX3	4	25	29	308.48
#500	TCF20	3	20	23	218.719