Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NKX2-1	53	2	55	472.663
#2	HOPX	35	4	39	432.082
#3	ARNTL2	35	8	43	929.326
#4	SNAI2	34	4	38	868.194
#5	FOXM1	31	2	33	488.379
#6	SOX2	31	7	38	1305.208
#7	E2F7	31	7	38	476.511
#8	MSC	30	11	41	1788.761
#9	IRX5	30	4	34	208.85
#10	FOXA2	29	15	44	1721.252
#11	HLF	29	5	34	569.375
#12	HMGA2	29	9	38	1117.099
#13	PPARG	29	10	39	1700.322
#14	MYBL2	29	8	37	1155.269
#15	GATA6	28	11	39	2337.454
#16	ZEB1	28	10	38	1348.401
#17	PROX1	28	8	36	1213.35
#18	ZNF256	28	5	33	600.284
#19	SIX2	28	7	35	1031.234
#20	HOXB2	27	10	37	2418.526
#21	EOMES	27	10	37	1405.663
#22	TFCP2L1	27	13	40	1432.309
#23	BHLHE41	26	9	35	857.116
#24	THRB	26	7	33	1189.643
#25	HIF3A	26	13	39	1966.707
#26	HOXD11	26	8	34	1070.934
#27	ZNF132	25	8	33	1117.124
#28	FOXA3	25	6	31	1042.704
#29	ETV4	24	12	36	1679.743
#30	TRIM29	24	5	29	510.409
#31	NR2F1	24	11	35	709.437
#32	PITX2	24	10	34	1812.305
#33	ZFHX4	24	10	34	1807.901
#34	PURB	23	12	35	1956.968
#35	PRRX1	23	1	24	13.626
#36	DMRT2	23	11	34	1870.617
#37	AR	23	14	37	1572.255
#38	FOXD2	22	9	31	1252.206
#39	KLF4	22	9	31	892.698
#40	FOSL1	22	10	32	1099.242
#41	SLC26A3	22	8	30	620.549
#42	IRX3	22	10	32	1291.343
#43	FOXE3	22	9	31	995.316
#44	IRX1	21	8	29	647.629
#45	ZNF157	21	10	31	1039.795
#46	HNF1A	21	13	34	2821.824
#47	SPDEF	21	7	28	633.738
#48	MYCL1	21	8	29	1038.717
#49	FOS	21	7	28	686.468
#50	FOXA1	21	9	30	805.049
#51	GRHL3	20	11	31	1574.189
#52	GSX2	20	9	29	893.049
#53	IKZF3	20	8	28	1086.042
#54	ALS2CR8	20	7	27	1286.267
#55	PITX1	20	15	35	1320.464
#56	ETV6	20	10	30	728.711
#57	ARX	20	12	32	1182.798
#58	PAX4	20	12	32	1719.27
#59	SATB2	20	8	28	860.62
#60	FOSB	20	13	33	1662.936
#61	MESP2	19	14	33	878.958
#62	AEBP1	19	7	26	697.456
#63	HOXD1	19	5	24	136.788
#64	TFEC	19	9	28	526.422
#65	CDX2	19	4	23	262.32
#66	HNF4A	19	10	29	995.398
#67	HOXA1	19	12	31	837.918
#68	VAX2	19	10	29	1110.587
#69	ZNF117	19	10	29	1138.99
#70	MEOX1	18	10	28	948.325
#71	MNX1	18	12	30	1393.024
#72	LZTS1	18	12	30	1712
#73	TFAP2C	18	12	30	1276.984
#74	SMAD3	18	14	32	1257.496
#75	SIX1	18	16	34	1075.597
#76	RARB	18	15	33	1554.191
#77	ASCL2	18	7	25	469.568
#78	ZNF135	18	12	30	1324.983
#79	HMGA1	18	8	26	631.68
#80	MNT	18	9	27	938.149
#81	RFX3	18	10	28	1141.334
#82	HOXC9	18	5	23	458.083
#83	SPI1	17	6	23	257.288
#84	IRX2	17	13	30	555.797
#85	HOXB7	17	8	25	762.373
#86	TSC22D1	17	10	27	1024.482
#87	CREB5	17	9	26	854.232
#88	SIM2	17	9	26	993.372
#89	DLX3	17	14	31	725.711
#90	SP140	17	7	24	561.393
#91	PKNOX1	17	14	31	1366.297
#92	SIX4	17	15	32	1700.012
#93	IRF6	17	12	29	1649.921
#94	TWIST1	17	7	24	379.078
#95	STAT5B	17	13	30	1312.275
#96	ARNT2	17	14	31	971.133
#97	RORC	17	13	30	1005.338
#98	POU4F1	17	15	32	1982.507
#99	MEIS3	17	14	31	1489.899
#100	C2orf3	17	12	29	1805.232
#101	MSX1	16	15	31	1221.046
#102	ALX4	16	8	24	816.213
#103	RCOR1	16	15	31	2224.281
#104	RUNX2	16	13	29	943.721
#105	BNC1	16	11	27	833.445
#106	SOX9	16	7	23	955.638
#107	HOXA9	16	10	26	1059.949
#108	CDKN2A	16	12	28	878.343
#109	PHOX2A	16	12	28	994.132
#110	L3MBTL4	16	13	29	1085.594
#111	HOXB9	16	3	19	196.621
#112	SOX30	16	15	31	1882.185
#113	ZSCAN18	16	12	28	1184.572
#114	EHF	16	11	27	1025.405
#115	NR1H4	16	22	38	2626.54
#116	SOX15	16	11	27	1088.557
#117	SOX21	16	11	27	1200.789
#118	FOXO6	16	15	31	1317.335
#119	POU4F3	16	11	27	1428.054
#120	LEF1	16	11	27	894.019
#121	TFAP2A	16	15	31	1341.686
#122	NR3C2	16	11	27	1319.178
#123	NR6A1	16	16	32	3104.199
#124	TRIM25	16	12	28	1230.919
#125	HES6	16	20	36	1226.541
#126	ZNF154	16	10	26	986.23
#127	HOXC12	15	14	29	1084.416
#128	GLI2	15	7	22	903.167
#129	MITF	15	16	31	1732.122
#130	PAX8	15	17	32	992.179
#131	POU5F2	15	11	26	792.15
#132	ZNF238	15	9	24	781.804
#133	ZNF131	15	7	22	788.027
#134	LASS5	15	13	28	1212.675
#135	ZNF92	15	9	24	701.148
#136	OTX1	15	13	28	1126.96
#137	SOX11	15	13	28	1191.293
#138	ALX1	15	16	31	1124.045
#139	RERE	15	12	27	1329.124
#140	OTX2	15	18	33	1409.808
#141	NR5A2	15	12	27	944.239
#142	FOXR2	15	10	25	952.873
#143	HOXD3	15	12	27	1098.446
#144	TCF3	15	11	26	1056.722
#145	FOXL1	15	14	29	1285.892
#146	MYCN	15	12	27	886.169
#147	ISX	15	17	32	1854.627
#148	FOXE1	15	10	25	804.391
#149	NFIX	14	16	30	602.274
#150	DMRT1	14	12	26	1181.901
#151	LHX2	14	21	35	1310.47
#152	RUNX1T1	14	14	28	1045.037
#153	HESX1	14	16	30	1030.695
#154	FOXD1	14	17	31	1049.195
#155	KCNH8	14	18	32	1307.645
#156	LHX1	14	21	35	1527.472
#157	RORA	14	13	27	916.714
#158	POU6F1	14	7	21	607.655
#159	IKZF1	14	8	22	671.237
#160	TBX15	14	16	30	1208.535
#161	TAF1B	14	14	28	1295.826
#162	NKX2-8	14	16	30	1173.487
#163	FOXQ1	14	21	35	1525.288
#164	CLOCK	14	10	24	1181.178
#165	MBD1	14	16	30	972.426
#166	TWIST2	14	8	22	1081.472
#167	NANOG	14	12	26	1067.421
#168	FOXK2	14	13	27	912.88
#169	TBX22	14	15	29	1087.449
#170	HOXB8	14	8	22	633.788
#171	GCM1	14	11	25	914.759
#172	HOXC11	14	12	26	696.035
#173	ZKSCAN3	14	15	29	1659.73
#174	HNF1B	14	14	28	769.251
#175	SIX3	13	18	31	2048.106
#176	ZFP42	13	20	33	2075.6
#177	WNT5A	13	13	26	1146.726
#178	C12orf28	13	7	20	790.908
#179	FOXL2	13	11	24	919.592
#180	KLF16	13	13	26	1001.101
#181	SP3	13	16	29	1632.41
#182	HSF5	13	13	26	1255.771
#183	TAF10	13	10	23	911.464
#184	ZNF33B	13	15	28	1156.613
#185	TFE3	13	9	22	778.187
#186	CREM	13	13	26	1141.213
#187	ZIC2	13	16	29	668.329
#188	LHX9	13	16	29	1616.138
#189	FOXN4	13	10	23	680.668
#190	ISL2	13	20	33	1049.811
#191	HMGB2	13	11	24	1034.741
#192	ZNF207	13	14	27	1029.274
#193	PAX6	13	15	28	1018.739
#194	DLX6	13	15	28	1584.638
#195	MGA	13	16	29	1161.609
#196	KLF17	13	15	28	1206.536
#197	POU2F1	13	14	27	1286.931
#198	PHOX2B	13	13	26	1052.557
#199	SCRT1	13	17	30	1090.205
#200	IRF5	13	12	25	1089.887
#201	MTA3	13	14	27	1392.355
#202	TBX10	13	13	26	1656.556
#203	DLX4	13	10	23	808.869
#204	ATOH1	13	11	24	1014.165
#205	ZNF215	13	17	30	1147.891
#206	NFIB	13	14	27	657.163
#207	HOXA3	12	5	17	142.258
#208	RBPJL	12	14	26	910.668
#209	ZBTB17	12	10	22	1007.54
#210	TAF4	12	14	26	948.807
#211	FOXH1	12	17	29	1300.004
#212	ZSCAN10	12	13	25	1397.868
#213	USF1	12	13	25	1000.73
#214	HOXA10	12	17	29	997.077
#215	POU3F4	12	17	29	2095.786
#216	ESRRG	12	14	26	1011.701
#217	TFAP2D	12	14	26	847.99
#218	ONECUT2	12	15	27	1040.871
#219	ZNF496	12	10	22	660.401
#220	REST	12	14	26	1289.603
#221	BARX1	12	18	30	1843.64
#222	MYNN	12	13	25	996.02
#223	ZNF90	12	10	22	919.491
#224	MSX2	12	10	22	1015.735
#225	SCAND3	12	13	25	1043.827
#226	TCF21	12	12	24	686.053
#227	NFYA	12	10	22	586.049
#228	ELF5	12	19	31	1023.858
#229	NKX3-2	12	12	24	982.051
#230	MAF	12	16	28	1135.875
#231	MLXIPL	12	10	22	806.79
#232	FOXP2	12	12	24	821.229
#233	SREBF1	12	12	24	757.885
#234	ZNF3	12	11	23	1040.688
#235	FOXC2	12	11	23	850.47
#236	ETV5	12	12	24	1004.577
#237	MYC	12	11	23	1070.031
#238	FOXG1	12	15	27	900.26
#239	NOBOX	12	9	21	800.319
#240	ZSCAN1	12	12	24	937.421
#241	POU3F1	12	14	26	1365.146
#242	TADA2A	12	10	22	779.474
#243	NKX6-1	12	10	22	813.13
#244	PCGF2	12	12	24	787.766
#245	NR4A3	12	10	22	567.629
#246	NEUROD2	12	13	25	837.957
#247	AFF4	11	14	25	1327.607
#248	TAL1	11	13	24	686.649
#249	HOXC10	11	6	17	369.907
#250	PRRX2	11	12	23	592.603
#251	FOXP3	11	13	24	859.088
#252	PRDM2	11	12	23	990.161
#253	MTA2	11	11	22	758.395
#254	GATAD1	11	12	23	1081.117
#255	POU1F1	11	13	24	774.214
#256	BCL11B	11	14	25	985.389
#257	POU3F2	11	12	23	1065.597
#258	NR2F6	11	8	19	644.217
#259	CREB3L1	11	11	22	1001.505
#260	MECOM	11	15	26	1348.075
#261	HNF4G	11	19	30	1223.381
#262	HOXB6	11	10	21	854.08
#263	MYF6	11	15	26	936.755
#264	PGR	11	12	23	847.879
#265	NRL	11	11	22	815.99
#266	SIM1	11	16	27	1152.739
#267	VTN	11	13	24	957.104
#268	NR5A1	11	12	23	706.21
#269	MESP1	11	13	24	887.281
#270	TSHZ2	11	8	19	392.14
#271	MZF1	11	8	19	658.744
#272	WT1	11	14	25	493.084
#273	ZNF287	11	14	25	1068.256
#274	HOXA13	11	16	27	1089.266
#275	ZIC3	11	17	28	1231.167
#276	SIX6	11	14	25	1006.727
#277	VSX1	11	16	27	1098.755
#278	POU2F2	11	13	24	529.111
#279	HMX1	11	12	23	616.402
#280	SMAD4	11	11	22	712.833
#281	FOXJ1	11	14	25	606.16
#282	NKX2-3	11	14	25	1193.237
#283	GLI3	10	14	24	666.779
#284	SALL1	10	13	23	1113.694
#285	MEOX2	10	8	18	524.267
#286	NR1I2	10	10	20	651.14
#287	PTH	10	20	30	1200.426
#288	ST18	10	12	22	1047.087
#289	PAX3	10	19	29	1300.507
#290	ZSCAN4	10	14	24	792.589
#291	GATA3	10	20	30	1061.664
#292	MYT1	10	17	27	1247.832
#293	ZNF81	10	11	21	754.011
#294	OVOL1	10	11	21	689.267
#295	TFDP3	10	14	24	763.511
#296	MXD1	10	9	19	553.128
#297	ARNT	10	14	24	990.402
#298	SCAND2	10	11	21	829.801
#299	OLIG2	10	13	23	737.934
#300	FOXO3	10	20	30	1197.864
#301	ESRRB	10	17	27	1335.26
#302	ETV1	10	8	18	319.819
#303	ONECUT1	10	11	21	663.146
#304	ZNF483	10	17	27	724.384
#305	SEBOX	10	9	19	567.228
#306	GSX1	10	9	19	521.208
#307	GATA4	10	12	22	923.089
#308	TBX5	10	10	20	636.226
#309	PBX1	10	16	26	1129.149
#310	MIXL1	10	12	22	529.023
#311	ZNF397	10	16	26	997.581
#312	THRA	10	12	22	483.537
#313	FOXC1	10	14	24	1174.888
#314	YY1	10	13	23	945.272
#315	TBX6	10	10	20	675.995
#316	HOXA2	10	13	23	886
#317	MAFK	10	14	24	1127.969
#318	RFXAP	10	15	25	1148.336
#319	GATAD2A	10	10	20	919.257
#320	SNAPC5	10	13	23	800.681
#321	NKX2-5	10	11	21	950.138
#322	KLF15	10	13	23	699.432
#323	HOXB1	10	11	21	1049.043
#324	ZBTB38	10	11	21	599.736
#325	PURA	10	12	22	588.606
#326	ATF5	10	16	26	1195.816
#327	GBX2	9	17	26	1014.942
#328	SOX1	9	16	25	1080.023
#329	POU3F3	9	9	18	505.955
#330	NFE2L2	9	12	21	742.481
#331	SOX5	9	14	23	754.042
#332	HR	9	10	19	519.59
#333	MYT1L	9	11	20	720.929
#334	TBX20	9	13	22	587.693
#335	ZNF628	9	13	22	944.486
#336	CREBBP	9	16	25	816.394
#337	PDX1	9	15	24	853.788
#338	FOXI1	9	12	21	708.974
#339	HNRNPAB	9	15	24	943.919
#340	TBX2	9	14	23	961.704
#341	E2F2	9	17	26	744.509
#342	HOXB13	9	12	21	590.041
#343	FOXN3	9	12	21	1133.674
#344	CREB3L3	9	10	19	714.67
#345	NR0B1	9	18	27	1384.566
#346	ZFP36L1	9	13	22	833.955
#347	PAX7	9	22	31	1253.276
#348	VENTX	9	11	20	757.513
#349	SRY	9	14	23	786.057
#350	ZSCAN2	9	12	21	616.62
#351	DLX2	9	22	31	1025.116
#352	ISL1	9	17	26	1028.687
#353	DMBX1	9	15	24	681.316
#354	TFAP4	9	13	22	835.701
#355	RELA	9	11	20	658.91
#356	EMX1	9	11	20	594.415
#357	CSDA	9	11	20	852.692
#358	FOXD3	9	16	25	1011.579
#359	SOX8	9	16	25	819.982
#360	TADA3	9	12	21	641.349
#361	NFATC1	9	12	21	807.529
#362	CITED1	9	14	23	937.474
#363	NPAT	9	14	23	1113.795
#364	HOXD9	9	14	23	821.413
#365	MLLT10	9	9	18	525.614
#366	KLF1	9	12	21	542.407
#367	ESX1	9	19	28	1249.732
#368	SOX6	9	12	21	1118.155
#369	RARA	9	10	19	505.81
#370	FLI1	9	13	22	807.044
#371	SUPT6H	9	13	22	680.172
#372	CUX2	8	13	21	796.94
#373	NFKB2	8	15	23	737.795
#374	ZNF639	8	16	24	835.106
#375	SOX13	8	12	20	761.907
#376	NPAS1	8	21	29	962.395
#377	TCF20	8	14	22	845.364
#378	CBL	8	15	23	674.589
#379	SMAD9	8	11	19	674.416
#380	NFATC4	8	12	20	405.351
#381	ALX3	8	16	24	715.309
#382	RARG	8	11	19	643.118
#383	TBX3	8	17	25	776.591
#384	SIN3A	8	16	24	712.995
#385	ZIC5	8	19	27	707.234
#386	NEUROD1	8	17	25	722.779
#387	T	8	13	21	609.669
#388	TEAD2	8	13	21	388.601
#389	TCF25	8	10	18	805.921
#390	C11orf9	8	11	19	802.534
#391	LMX1A	8	12	20	871.553
#392	HOXA11	8	14	22	1051.066
#393	IRX4	8	13	21	562.492
#394	HIC1	8	13	21	618.078
#395	ELK1	8	8	16	524.387
#396	TFAP2B	8	19	27	951.811
#397	RUNX1	8	16	24	748.975
#398	KLF9	8	15	23	630.751
#399	TULP4	8	15	23	809.099
#400	NR4A1	8	13	21	539.765
#401	HOXC8	8	13	21	1049.756
#402	HOXD13	8	12	20	500.98
#403	HOXD10	8	13	21	731.964
#404	ZNF19	8	11	19	725.352
#405	FOXO1	8	18	26	1400.879
#406	HMG20B	8	15	23	946.957
#407	CTBP1	8	18	26	756.226
#408	HCFC1	8	15	23	800.206
#409	PBX3	8	16	24	1164.616
#410	LMO4	7	11	18	538.006
#411	SMAD6	7	16	23	628.255
#412	TBX4	7	10	17	441.82
#413	ZSCAN23	7	13	20	432.715
#414	DLX1	7	17	24	991.503
#415	CEBPE	7	9	16	402.967
#416	NR2E1	7	22	29	1011.311
#417	NCOR1	7	14	21	742.775
#418	HES5	7	15	22	582.251
#419	ANKRD30A	7	12	19	665.987
#420	HEY2	7	11	18	393.831
#421	TLX3	7	15	22	713.623
#422	NFIA	7	13	20	866.826
#423	TBX1	7	15	22	662.592
#424	SPIB	7	12	19	495.246
#425	KLF12	7	16	23	564.254
#426	ZFHX2	7	12	19	614.735
#427	ZFP36L2	7	17	24	779.583
#428	TRERF1	7	12	19	573.05
#429	HOXC13	7	10	17	408.037
#430	SPIC	7	16	23	641.316
#431	ZNF396	7	15	22	938.854
#432	EGR4	7	17	24	605.793
#433	ESR2	7	15	22	606.135
#434	NPAS2	7	16	23	817.465
#435	ATF7	7	9	16	287.556
#436	NR1I3	7	14	21	665.418
#437	ZHX3	7	13	20	799.568
#438	EN2	7	12	19	732.421
#439	FOXK1	7	13	20	469.297
#440	MKX	7	8	15	337.373
#441	MLL	7	14	21	578.127
#442	EVX1	7	14	21	537.675
#443	LHX8	6	17	23	661.055
#444	GATA5	6	17	23	503.984
#445	CREBZF	6	17	23	403.266
#446	HAND2	6	17	23	650.222
#447	TLX2	6	17	23	593.594
#448	FOXB1	6	10	16	310.217
#449	EN1	6	13	19	613.031
#450	VDR	6	14	20	375.276
#451	TSC22D2	6	18	24	994.967
#452	ZIC1	6	15	21	653.286
#453	CSRNP3	6	11	17	409.817
#454	ZNF85	6	16	22	710.873
#455	FOXD4	6	12	18	387.697
#456	TSC22D3	6	18	24	504.114
#457	POU4F2	6	16	22	904.279
#458	PPARA	6	14	20	677.367
#459	ELK4	6	9	15	530.775
#460	GSC2	6	15	21	750.611
#461	FUBP1	6	13	19	570.884
#462	FOXJ2	6	14	20	459.617
#463	PPARD	6	14	20	460.222
#464	NEUROG1	6	11	17	473.167
#465	IRF4	6	14	20	491.776
#466	ZNF175	6	10	16	415.995
#467	ZNF71	6	13	19	710.754
#468	HIRA	6	13	19	586.059
#469	ASCL1	6	22	28	573.025
#470	MYF5	6	11	17	593.406
#471	RCAN1	6	18	24	771.674
#472	RAX2	6	12	18	441.294
#473	NFE2	5	18	23	705.305
#474	POU6F2	5	21	26	786.432
#475	ESR1	5	16	21	632.254
#476	PKNOX2	5	14	19	612.32
#477	TBR1	5	12	17	438.375
#478	ERF	5	17	22	806.507
#479	TP63	5	15	20	500.108
#480	POU2F3	5	15	20	967.554
#481	NKX6-2	5	12	17	922.171
#482	HAND1	5	17	22	767.655
#483	ZNF80	5	16	21	496.439
#484	ZFHX3	5	13	18	671.358
#485	BRD8	5	10	15	362.027
#486	HOXD4	5	15	20	560.471
#487	NFATC2	5	13	18	643.313
#488	TEF	5	13	18	696.269
#489	TP73	5	10	15	329.679
#490	ETV3	5	13	18	453.863
#491	RORB	4	12	16	284.156
#492	EPAS1	4	9	13	166.094
#493	ZNF93	4	13	17	333.915
#494	JUND	4	15	19	407.895
#495	ZSCAN12	4	15	19	390.629
#496	HOXB3	4	8	12	265.544
#497	PAX5	3	15	18	277.171
#498	KDM5B	3	14	17	319.887
#499	ZNF167	3	12	15	380.058
#500	SLC2A4RG	2	18	20	307.905