Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HAND1	51	1	52	410.192
#2	AFF4	49	4	53	298.603
#3	GATA4	43	4	47	448.86
#4	STAT2	42	7	49	540.471
#5	PLAGL2	37	6	43	224.501
#6	MLXIPL	33	2	35	138.615
#7	HIF3A	33	5	38	212.636
#8	ESR2	33	12	45	3351.128
#9	CREB1	32	6	38	1553.506
#10	SIN3A	31	11	42	662.433
#11	VDR	31	6	37	219.952
#12	SOX8	29	4	33	5666.965
#13	VAX2	29	10	39	277.137
#14	NR3C1	28	5	33	1096.107
#15	RBCK1	27	7	34	175.199
#16	SOLH	27	11	38	3612.928
#17	ZIC5	27	7	34	379.642
#18	RB1	26	5	31	344.314
#19	FOXE1	26	5	31	90.659
#20	PDX1	26	11	37	1269.592
#21	CTCF	25	5	30	124.121
#22	DMTF1	24	9	33	1164.122
#23	ZNF93	24	7	31	3583.872
#24	NFE2	24	5	29	142.64
#25	HMG20A	23	4	27	199.762
#26	TAF10	23	11	34	335.034
#27	IRF7	23	5	28	370.523
#28	ESRRG	23	9	32	1688.316
#29	MECOM	23	8	31	238.977
#30	FUBP1	22	1	23	15.158
#31	IKZF1	22	16	38	1946.436
#32	RORA	22	9	31	392.236
#33	TEF	22	3	25	127.139
#34	SMAD6	22	10	32	2189.197
#35	FOXJ1	21	8	29	332.952
#36	PURB	21	4	25	109.832
#37	USF1	21	9	30	435.193
#38	TP73	21	4	25	298.144
#39	IRF6	21	14	35	1041.915
#40	NFIA	21	13	34	2687.584
#41	HNF4A	21	8	29	112.803
#42	JUNB	20	6	26	358.072
#43	POU2F1	20	12	32	3297.557
#44	NR1I3	20	12	32	2476.589
#45	IRF5	20	7	27	740.272
#46	CREM	20	12	32	1885.276
#47	NFKB1	20	13	33	1473.728
#48	SIX4	20	7	27	1852.227
#49	RXRA	20	10	30	1587.201
#50	GTF2I	19	4	23	104.984
#51	GSC2	19	8	27	381.351
#52	TSC22D4	19	12	31	1158.795
#53	USF2	19	7	26	843.86
#54	ARNTL2	19	5	24	467.28
#55	ZNF323	19	12	31	1532.886
#56	HOXB1	19	7	26	114.039
#57	MAF	19	5	24	598.501
#58	KLF6	19	6	25	2591.292
#59	ATF7	19	3	22	45.492
#60	NOTCH1	18	4	22	265.216
#61	ZHX3	18	8	26	865.708
#62	NPAT	18	12	30	3336.638
#63	SMAD4	18	0	18	0
#64	CITED2	18	8	26	812.428
#65	L3MBTL4	17	6	23	380.687
#66	HSF5	17	9	26	235.164
#67	TLX2	17	8	25	246.53
#68	KCNH8	17	15	32	1254.198
#69	HOXC12	17	3	20	41.882
#70	TFAP4	16	8	24	1075.063
#71	E2F2	16	6	22	153.925
#72	SOX1	16	13	29	1515.743
#73	FBXW7	16	10	26	1970.342
#74	POU2F2	16	11	27	1468.582
#75	GSC	16	3	19	127.901
#76	TBX5	16	8	24	275.408
#77	STAT3	16	8	24	52.231
#78	FOXP1	15	6	21	551.076
#79	BLZF1	15	7	22	212.708
#80	ZNF138	15	6	21	223.854
#81	ZNF134	15	4	19	88.764
#82	XBP1	15	11	26	1948.668
#83	TFE3	15	10	25	1479.482
#84	TCF15	15	11	26	642.611
#85	SOX7	15	3	18	265.844
#86	SIX6	15	15	30	941.947
#87	SHOX	15	16	31	1474.867
#88	FOXA1	15	8	23	255.78
#89	FOXA2	15	12	27	2729.672
#90	PTH	15	9	24	293.578
#91	PRRX1	15	8	23	1539.945
#92	NR2F2	15	15	30	2917.188
#93	NR1H4	15	11	26	4707.533
#94	MYT1L	15	7	22	344.98
#95	MLL	15	17	32	3490.68
#96	LASS2	15	7	22	1061.488
#97	HOXA7	15	6	21	178.08
#98	ZXDA	14	8	22	343.716
#99	SP1	14	2	16	25.746
#100	TAF5L	14	8	22	389.57
#101	HSF2	14	7	21	187.205
#102	E2F4	14	13	27	2379.878
#103	DMRT2	14	4	18	521.732
#104	HOXC10	14	11	25	573.098
#105	DLX2	14	10	24	469.027
#106	ZNF197	14	3	17	95.846
#107	PA2G4	14	10	24	1457.191
#108	PITX1	14	11	25	788.126
#109	ZNF217	14	11	25	427.325
#110	ZNF167	13	14	27	6754.378
#111	HMGB1	13	15	28	1784.306
#112	HMGB2	13	7	20	301.257
#113	PROX1	13	10	23	2104.008
#114	TGIF1	13	7	20	124.225
#115	ZNF213	13	8	21	997.986
#116	ATF6	13	4	17	547.037
#117	ZFPM2	13	9	22	274.872
#118	RAX2	13	8	21	398.019
#119	FOXJ2	13	8	21	803.404
#120	RCOR1	13	7	20	1188.658
#121	HCFC1	13	17	30	1293.983
#122	HOXD9	13	10	23	2412.566
#123	SPDEF	13	4	17	544.608
#124	STAT4	13	17	30	3023.603
#125	C1orf85	13	11	24	2083.008
#126	TBX21	13	14	27	458.011
#127	IRX1	13	11	24	1866.138
#128	MYC	13	8	21	373.601
#129	KLF12	12	10	22	3227.105
#130	ATF1	12	5	17	31.357
#131	ATF4	12	11	23	871.11
#132	CNBP	12	10	22	727.409
#133	CREB3L3	12	11	23	2594.06
#134	FOXP4	12	13	25	1254.13
#135	GSX2	12	7	19	245.683
#136	JUND	12	9	21	425.353
#137	MNT	12	10	22	400.082
#138	NFKB2	12	7	19	175.597
#139	NRL	12	11	23	962.579
#140	RBPJ	12	4	16	2011.673
#141	RELB	12	11	23	594.622
#142	SCAND2	12	13	25	590.505
#143	SOX2	12	6	18	144.353
#144	STRN3	12	7	19	190.314
#145	TAF12	12	6	18	319.818
#146	TFAP2D	12	8	20	942.52
#147	TFCP2L1	12	7	19	1268.264
#148	TLX1	12	6	18	276.395
#149	HNRNPAB	11	4	15	80.313
#150	SOX15	11	10	21	1040.629
#151	VTN	11	13	24	710.596
#152	MAX	11	5	16	963.203
#153	GTF2H3	11	18	29	589.605
#154	ERG	11	10	21	2935.427
#155	LBX2	11	7	18	246.553
#156	TRIM25	11	7	18	474.881
#157	ARNT	10	11	21	430.335
#158	ZSCAN21	10	7	17	321.203
#159	HOXB3	10	16	26	2852.355
#160	PGR	10	10	20	876.214
#161	PEG3	10	11	21	1173.217
#162	TCFL5	10	14	24	1792.23
#163	FOXO3	10	7	17	1245.819
#164	HOXC8	10	12	22	1875.589
#165	E2F6	10	12	22	610.394
#166	HOXB7	10	13	23	3292.03
#167	BACH1	10	7	17	184.324
#168	BUD31	10	10	20	1146.065
#169	MKX	10	8	18	961.269
#170	C11orf9	10	16	26	1071.037
#171	RFX1	10	12	22	578.544
#172	ZNF445	10	15	25	4405.017
#173	NR1D2	10	11	21	1359.077
#174	ETS2	10	5	15	263.145
#175	E2F1	10	16	26	3176.767
#176	MSX2	10	9	19	1501.841
#177	NME2	10	13	23	960.337
#178	TP53	10	16	26	2388.786
#179	ZNF397	10	13	23	1093.799
#180	NFE2L1	10	9	19	1829.479
#181	HIF1A	10	9	19	1935.94
#182	IKZF3	10	11	21	2354.852
#183	FOXQ1	10	12	22	527.003
#184	ZNF91	9	11	20	1101.551
#185	RHOXF2B	9	13	22	1269.765
#186	SATB2	9	12	21	325.264
#187	ZNF207	9	8	17	193.148
#188	MEIS3	9	10	19	972.258
#189	MLX	9	7	16	1003.25
#190	HNF1A	9	8	17	617.597
#191	YBX1	9	10	19	756.841
#192	UBN1	9	11	20	5895.371
#193	IRX4	9	11	20	1851.081
#194	TRIM22	9	8	17	784.148
#195	NFYA	9	9	18	96.049
#196	NKX2-1	9	7	16	1586.741
#197	HDAC1	9	8	17	128.887
#198	NR1I2	9	7	16	276.627
#199	KLF2	9	13	22	319.545
#200	IRX3	9	13	22	1501.744
#201	NR4A3	9	4	13	108.279
#202	TCF7	9	7	16	1013.301
#203	GATA6	9	12	21	65.895
#204	ELF5	9	8	17	993.075
#205	T	9	8	17	303.912
#206	SUPT4H1	9	9	18	319.692
#207	EN1	9	11	20	1446.89
#208	EPAS1	9	9	18	556.538
#209	ZNF90	9	12	21	2855.94
#210	CCRN4L	8	12	20	140.996
#211	HOXD8	8	19	27	2293.925
#212	MAFA	8	9	17	744.873
#213	HOPX	8	14	22	2143.376
#214	TWIST1	8	11	19	292.524
#215	RHOXF2	8	8	16	954.11
#216	HNRNPK	8	8	16	725.22
#217	TP63	8	13	21	541.841
#218	HES6	8	10	18	617.109
#219	ASCL2	8	10	18	335.497
#220	CDKN2A	8	12	20	560.283
#221	TFAP2C	8	9	17	854.381
#222	TMEM229A	8	15	23	809.462
#223	TCF7L2	8	14	22	1126.481
#224	NKX2-3	8	8	16	612.51
#225	SOX11	8	11	19	627.331
#226	RXRG	8	12	20	402.586
#227	TFAP2B	8	17	25	1638.634
#228	SMAD2	8	17	25	242.233
#229	ZNF238	8	7	15	260.285
#230	SMAD5	7	8	15	306.18
#231	RXRB	7	7	14	1261.393
#232	MTF1	7	11	18	598.448
#233	MTA3	7	12	19	890.547
#234	GTF2IRD1	7	15	22	1603.819
#235	SPIC	7	11	18	768.13
#236	MEIS2	7	8	15	799.912
#237	SOX12	7	10	17	178.882
#238	ETV3L	7	14	21	830.791
#239	SMAD1	7	11	18	737.44
#240	E4F1	7	11	18	3225.768
#241	TEAD1	7	10	17	2120.807
#242	ATF3	7	9	16	681.986
#243	ESR1	7	11	18	3666.382
#244	ECSIT	7	10	17	879.266
#245	TBX4	7	16	23	1431.692
#246	PITX3	7	11	18	1243.565
#247	FOXM1	7	10	17	494.455
#248	FOXK1	7	7	14	253.574
#249	PLSCR1	7	8	15	349.31
#250	JDP2	7	9	16	2300.858
#251	RFX3	7	10	17	1632.917
#252	NCOR1	7	7	14	146.94
#253	PPARA	7	10	17	207.16
#254	CNOT7	7	5	12	46.907
#255	FOXO4	6	15	21	1490.45
#256	KLF15	6	18	24	2076.768
#257	MNX1	6	18	24	3280.199
#258	NFATC3	6	10	16	322.706
#259	ZNF446	6	7	13	447.81
#260	GCM1	6	12	18	240.266
#261	GBX1	6	5	11	57.874
#262	NR5A1	6	15	21	1487.014
#263	GATA2	6	16	22	527.74
#264	PPARG	6	19	25	1863.128
#265	ETV6	6	15	21	886.131
#266	ZSCAN16	6	14	20	1321.15
#267	SOX30	6	16	22	1483.34
#268	ENO1	6	9	15	1035.357
#269	SRY	6	15	21	1769.977
#270	STAT1	6	15	21	892.676
#271	ZSCAN22	6	11	17	284.622
#272	TAL1	6	11	17	3252.372
#273	ZXDC	6	8	14	375.745
#274	YEATS4	6	15	21	1226.227
#275	ZC3H8	6	6	12	40.312
#276	ZNF189	6	14	20	1663.395
#277	ZNF37A	6	16	22	879.808
#278	IRF2	6	14	20	872.108
#279	IRF3	6	10	16	352.355
#280	HOXC9	6	14	20	622.541
#281	TSHZ1	5	12	17	1084.595
#282	RFX5	5	15	20	1988.974
#283	HESX1	5	19	24	293.584
#284	NFX1	5	11	16	1338.216
#285	CTNNB1	5	18	23	1366.353
#286	NPAS2	5	18	23	453.443
#287	TCF20	5	12	17	2794.021
#288	TFDP2	5	9	14	440.846
#289	ZSCAN4	5	16	21	1203.783
#290	ZNF256	5	13	18	830.992
#291	ZNF496	5	7	12	129.238
#292	LHX3	5	17	22	684.555
#293	LMX1B	5	12	17	436.115
#294	PRDM1	5	12	17	141.72
#295	PPARD	5	14	19	746.364
#296	MAFK	5	7	12	666.742
#297	POU4F2	5	8	13	320.936
#298	KLF3	5	17	22	2288.875
#299	MGA	5	12	17	1764.714
#300	FOXH1	5	11	16	271.687
#301	MSL3	5	14	19	322.982
#302	KLF4	5	12	17	1481.64
#303	HMG20B	5	17	22	1391.124
#304	VSX1	5	13	18	2821.033
#305	FOXR1	5	9	14	345.516
#306	CREBBP	5	12	17	333.715
#307	RFXANK	5	24	29	654.016
#308	CREBL2	5	12	17	775.914
#309	HOXB6	5	9	14	521.416
#310	NEUROD2	5	12	17	1413.213
#311	SALL1	5	16	21	1590.372
#312	RUNX1	5	16	21	948.361
#313	FOXP2	5	13	18	360.362
#314	RUNX2	5	9	14	118.463
#315	REXO4	4	11	15	424.814
#316	RELA	4	12	16	1244.088
#317	ZNF33A	4	12	16	2237.699
#318	HOXA4	4	16	20	370.954
#319	GABPB1	4	13	17	557.603
#320	ELF4	4	12	16	306.848
#321	TAF7	4	15	19	2038.687
#322	HOXD4	4	11	15	309.145
#323	TBX19	4	7	11	309.813
#324	ELF1	4	8	12	944.808
#325	PAX7	4	12	16	608.762
#326	TFAM	4	13	17	473.7
#327	TFCP2	4	6	10	444.104
#328	AHCTF1	4	5	9	87.769
#329	TGIF2	4	14	18	449.672
#330	TGIF2LY	4	13	17	412.743
#331	HOXD1	4	14	18	707.734
#332	CSRNP3	4	9	13	702.764
#333	HIRA	4	10	14	400.22
#334	YY1	4	14	18	771.683
#335	ZBTB38	4	12	16	519.488
#336	MLLT10	4	15	19	1961.7
#337	BTAF1	4	12	16	797.035
#338	MBD1	4	10	14	203.783
#339	RORB	4	6	10	143.421
#340	SCML2	4	10	14	147.136
#341	FOSL1	4	12	16	906.478
#342	SIM2	4	13	17	690.142
#343	ZFHX3	3	6	9	190.551
#344	IRX5	3	13	16	317.502
#345	C12orf28	3	11	14	1545.107
#346	CTBP1	3	16	19	622.717
#347	ZIC3	3	16	19	470.781
#348	ZNF215	3	6	9	201.725
#349	HOXA1	3	14	17	705.831
#350	POU3F2	3	15	18	2598.08
#351	SMAD3	3	11	14	525.994
#352	NANOG	3	9	12	34.02
#353	PKNOX1	3	7	10	39.266
#354	POU1F1	3	15	18	422.881
#355	AR	3	21	24	1561.32
#356	HOXB4	3	11	14	128.941
#357	NFE2L3	3	17	20	720.253
#358	MYF5	3	11	14	694.807
#359	PHF5A	3	15	18	148.767
#360	MSRB2	3	18	21	204.213
#361	FOXC1	3	15	18	329.583
#362	SCML1	3	15	18	389.707
#363	ESRRA	3	13	16	3971.41
#364	GATAD1	3	11	14	233.831
#365	ZFP37	3	12	15	293.298
#366	OVOL1	2	15	17	244.034
#367	NEUROG1	2	3	5	25.226
#368	FOXG1	2	14	16	429.426
#369	TAF1B	2	14	16	193.696
#370	ELK1	2	11	13	38.751
#371	ELK4	2	13	15	224.054
#372	JUN	2	10	12	250.03
#373	EMX1	2	11	13	217.592
#374	ZIC2	2	12	14	599.57
#375	MEOX1	2	11	13	567.212
#376	SPEN	2	11	13	128.12
#377	ETV7	2	9	11	29.342
#378	SOX5	2	18	20	1283.149
#379	TEAD3	2	12	14	971.403
#380	NFYB	2	13	15	480.371
#381	PRDM2	2	16	18	367.843
#382	DLX4	2	15	17	1010.271
#383	LCOR	2	18	20	645.085
#384	EHF	1	15	16	62.289
#385	GRHL3	1	17	18	432.725
#386	ZNF154	1	15	16	437.041
#387	ZNF18	1	12	13	317.239
#388	PHOX2B	1	6	7	22.078
#389	ATF6B	1	15	16	43.846
#390	TCF4	1	14	15	512.778
#391	ETV1	1	12	13	67.54
#392	TBX10	1	7	8	20.167
#393	FOXN3	1	17	18	163.94
#394	ZNF281	1	13	14	100.137
#395	OTX2	1	15	16	445.415
#396	FOXO1	0	19	19	0
#397	PBX3	0	12	12	0
#398	ZKSCAN1	0	12	12	0
#399	SOX21	0	19	19	0
#400	CEBPB	0	17	17	0
#401	TCF12	0	11	11	0
#402	PAX3	0	5	5	0