Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SPEN	72	4	76	177.52
#2	POU4F2	71	4	75	212.907
#3	THRB	71	6	77	2835.602
#4	HNF4A	70	6	76	1524.282
#5	PHOX2B	65	6	71	526.169
#6	TCF25	62	2	64	241.389
#7	PKNOX2	58	6	64	233.638
#8	EDF1	56	5	61	1182.836
#9	MAFB	56	2	58	618.057
#10	NEUROD2	53	10	63	3350.71
#11	ZFPM2	48	3	51	459.039
#12	RFXANK	47	5	52	5551.276
#13	FOXK2	47	6	53	258.973
#14	YBX1	46	2	48	503.043
#15	ENO1	46	2	48	59.844
#16	GATAD1	46	6	52	516.474
#17	NFYC	46	7	53	1307.564
#18	CREB3L1	43	9	52	238.642
#19	TBR1	43	9	52	5637.63
#20	RUNX1T1	42	7	49	953.295
#21	STAT3	42	7	49	1203.64
#22	SMAD5	41	8	49	1930.189
#23	MZF1	40	10	50	806.549
#24	PKNOX1	39	6	45	1076.998
#25	MAX	39	7	46	522.395
#26	KLF15	38	13	51	380.638
#27	FLI1	38	8	46	2960.291
#28	MECOM	38	9	47	446.779
#29	GTF2H3	37	5	42	1730.509
#30	MEOX2	36	8	44	468.972
#31	HMG20B	36	5	41	393.582
#32	SNAI2	36	1	37	5.649
#33	MEIS2	35	9	44	1023.508
#34	ZBTB48	35	10	45	3673.179
#35	TRIM22	34	3	37	91.982
#36	DLX4	33	20	53	2948.549
#37	JUND	33	12	45	2284.861
#38	ZFP36L2	33	12	45	2169.958
#39	NFATC3	33	9	42	867.228
#40	BHLHE41	33	9	42	495.109
#41	HMGA2	31	14	45	1640.162
#42	BHLHE40	31	9	40	1185.332
#43	ETV1	30	9	39	1607.437
#44	KLF1	30	12	42	1584.251
#45	SPDEF	30	6	36	458.513
#46	KLF9	30	11	41	615.47
#47	SPIB	30	15	45	1174.682
#48	LMO4	29	17	46	1726.327
#49	CNOT8	29	14	43	3456.655
#50	TWIST1	29	15	44	1172.695
#51	SOX4	28	9	37	369.41
#52	AEBP1	28	8	36	512.22
#53	CLOCK	28	12	40	912.024
#54	ZEB2	28	10	38	1212.088
#55	SIX6	27	13	40	890.674
#56	TCF7L2	27	11	38	2455.638
#57	HOPX	27	8	35	936.646
#58	ATF1	26	7	33	496.108
#59	ETS1	26	13	39	1492.972
#60	FOXF1	26	11	37	1856.39
#61	CBL	26	16	42	1945.401
#62	HOXA9	26	17	43	1771.375
#63	ARNTL	25	13	38	993.189
#64	ATF7	25	9	34	146.801
#65	ZNF500	25	15	40	1234.047
#66	ZNF91	24	8	32	1425.171
#67	ZFP36L1	24	14	38	771.787
#68	YEATS4	24	8	32	1058.089
#69	PPARG	24	12	36	900.16
#70	ZNF24	24	18	42	2826.478
#71	FOXN3	24	10	34	1106.983
#72	TCF4	24	10	34	1824.698
#73	NFYA	24	15	39	957.352
#74	MAF	23	13	36	432.599
#75	KLF12	23	19	42	3101.056
#76	KLF6	23	9	32	350.432
#77	NFYB	23	10	33	1184.118
#78	KLF4	23	14	37	913.946
#79	PBX1	23	11	34	1377.068
#80	TP53	23	14	37	1550.167
#81	AFF1	22	12	34	239.875
#82	ATF6	22	13	35	1061.081
#83	MLL	22	13	35	1051.696
#84	ZNF131	22	14	36	3522.228
#85	ZSCAN18	22	11	33	329.557
#86	ELF1	22	9	31	1257.4
#87	EGR1	22	9	31	927.759
#88	HOXA5	22	10	32	1269.654
#89	FOS	22	12	34	663.384
#90	E2F5	22	14	36	1524.8
#91	IRF8	22	8	30	234.571
#92	ZNF238	22	17	39	3075.78
#93	CITED2	22	14	36	1264.455
#94	NR4A1	22	10	32	655
#95	VDR	21	18	39	1306.386
#96	RXRG	21	16	37	2241.026
#97	RUNX2	21	11	32	695.724
#98	MEOX1	21	10	31	1352.984
#99	NR1I3	21	11	32	266.449
#100	ZNF41	20	14	34	3294.366
#101	NFAT5	20	9	29	1122.458
#102	SMAD6	20	19	39	2494.509
#103	ZNF394	20	9	29	1066.634
#104	CREBBP	20	14	34	341.137
#105	ETV5	20	11	31	1238.733
#106	NPAT	20	14	34	589.83
#107	ELK4	20	11	31	471.725
#108	ZNF45	20	14	34	838.59
#109	NR2F1	20	10	30	193.41
#110	NR2E3	19	15	34	899.495
#111	PURA	19	8	27	710.299
#112	LHX6	19	13	32	538
#113	HNF1B	19	14	33	300.041
#114	SOX10	18	10	28	2848.736
#115	ZKSCAN1	18	16	34	1078.818
#116	HOXC10	18	7	25	765.02
#117	IKZF1	18	15	33	1654.71
#118	SMAD9	18	17	35	1492.417
#119	DRAP1	18	8	26	739.31
#120	CSDA	18	17	35	753.625
#121	HIC1	18	15	33	419.909
#122	NFX1	18	14	32	1316.808
#123	SOX9	18	12	30	500.225
#124	GABPA	18	12	30	1084.63
#125	NKX3-2	18	14	32	559.764
#126	PLSCR1	18	13	31	2078.14
#127	HOXC11	18	14	32	371.824
#128	HSF1	18	12	30	1522.355
#129	POU6F1	18	16	34	1593.732
#130	ZNF192	18	14	32	526.177
#131	EGR2	17	11	28	369.506
#132	ASCL2	17	13	30	2397.109
#133	NR2F6	17	13	30	943.242
#134	TP63	17	17	34	771.256
#135	SNAPC4	17	11	28	310.204
#136	FOXM1	17	16	33	1198.071
#137	NR2C1	17	17	34	1083.784
#138	GATA6	17	15	32	652.777
#139	HEYL	17	16	33	1665.192
#140	HIRA	17	13	30	1022.904
#141	ZIC3	17	16	33	1520.485
#142	EVX1	17	12	29	958.467
#143	CSRNP3	17	15	32	737.675
#144	TFEC	17	12	29	1503.479
#145	NR2F2	17	8	25	484.097
#146	TCF12	17	15	32	1318.155
#147	GTF2I	16	9	25	868.784
#148	ZNF444	16	18	34	1250.953
#149	TRIM29	16	14	30	2458.186
#150	BCL3	16	20	36	2728.525
#151	MYC	16	11	27	782.02
#152	ZXDC	16	10	26	1662.238
#153	MTF1	16	11	27	301.887
#154	ZFHX3	16	15	31	1107.918
#155	EN1	16	14	30	1818.213
#156	ATF6B	16	16	32	956.511
#157	BACH1	16	15	31	2008.64
#158	MLLT10	16	12	28	1638.856
#159	ESR1	16	12	28	435.883
#160	FOSB	16	4	20	128.894
#161	HSF4	16	16	32	973.823
#162	RUNX3	16	11	27	607.718
#163	ZNF167	15	17	32	4831.067
#164	NFKB2	15	12	27	758.136
#165	SUPT6H	15	14	29	1000.727
#166	SATB1	15	17	32	1312.535
#167	IRX5	15	10	25	766.475
#168	REL	15	15	30	2430.078
#169	CBFA2T3	15	11	26	1485.717
#170	JUN	15	14	29	743.958
#171	RARA	15	14	29	594.019
#172	MEF2A	15	14	29	982.125
#173	CTBP1	15	13	28	819.449
#174	MBD1	15	19	34	691.44
#175	AR	15	14	29	663.131
#176	SOX21	15	18	33	1025.842
#177	MSC	15	14	29	1036.476
#178	STAT1	15	17	32	1996.373
#179	TFEB	14	16	30	823.694
#180	MYT1	14	18	32	2001.375
#181	HOXA2	14	11	25	427.452
#182	NR6A1	14	10	24	1057.667
#183	GLI2	14	16	30	1294.721
#184	BTG2	14	13	27	608.005
#185	POU2F2	14	12	26	477.884
#186	MYF6	14	15	29	1397.208
#187	WT1	14	18	32	4380.369
#188	OLIG2	14	11	25	816.899
#189	HCFC1	14	17	31	819.602
#190	HOXA3	14	15	29	1062.456
#191	HEY2	14	14	28	396.298
#192	TADA3	14	19	33	2310.529
#193	HMGA1	14	13	27	765.025
#194	PAX5	14	18	32	1639.911
#195	E2F4	14	13	27	589.902
#196	HOXB6	13	15	28	2115.601
#197	FOXI1	13	16	29	2088.665
#198	PAX4	13	17	30	1899.363
#199	MYCL1	13	16	29	919.668
#200	RARG	13	14	27	329.393
#201	NEUROG1	13	17	30	2761.807
#202	ATF3	13	7	20	480.178
#203	SCRT1	13	9	22	1811.752
#204	TFAP2C	13	15	28	2105.868
#205	AHR	13	17	30	894.293
#206	TAF12	13	17	30	892.586
#207	PHOX2A	13	12	25	338.718
#208	FUBP1	13	21	34	1267.785
#209	SP1	13	21	34	1779.712
#210	MAFK	13	13	26	1139.642
#211	RAX	13	16	29	1426.887
#212	RFX3	13	13	26	1086.071
#213	NR1H4	13	12	25	2611.123
#214	PRRX2	13	16	29	2146.825
#215	SPI1	13	18	31	3631.522
#216	HOXD10	13	14	27	1512.726
#217	VTN	13	18	31	704.304
#218	POU5F1B	13	14	27	1935.374
#219	TCF15	12	17	29	1131.161
#220	HLF	12	11	23	634.751
#221	YY1	12	14	26	2821.793
#222	SREBF1	12	17	29	785.619
#223	HOXD9	12	12	24	1597.754
#224	PPBPL2	12	21	33	1400.896
#225	HIF3A	12	15	27	1897.962
#226	HOXC8	12	14	26	2077.645
#227	HOXC5	12	15	27	700.044
#228	NR2C2	12	17	29	1675.456
#229	C2orf3	12	10	22	1307.249
#230	HOXD11	12	15	27	879.187
#231	NFIB	12	15	27	715.167
#232	FOXB1	12	16	28	1452.353
#233	WNT5A	12	14	26	647.066
#234	TFAP2A	12	17	29	1899.712
#235	MYBL2	12	11	23	280.079
#236	FOXO3	12	16	28	920.372
#237	AFF4	12	15	27	2687.932
#238	ERG	12	17	29	2087.195
#239	ALX3	12	14	26	819.598
#240	ZEB1	12	15	27	557.051
#241	HHEX	12	13	25	751.665
#242	HSF2	12	14	26	1866.371
#243	CEBPD	12	13	25	1451.937
#244	ZSCAN12	11	15	26	1678.129
#245	NR5A1	11	11	22	390.478
#246	SIX2	11	15	26	1661.453
#247	TLX3	11	16	27	719.842
#248	FOXE1	11	12	23	486.921
#249	PGR	11	23	34	1252.161
#250	ONECUT1	11	20	31	995.351
#251	ZNF117	11	16	27	1444.931
#252	IKZF3	11	16	27	483.711
#253	HMX1	11	15	26	853.398
#254	EHF	11	25	36	2622.954
#255	TBX19	11	18	29	1193.87
#256	ARNT	11	15	26	1341.026
#257	TBX3	11	14	25	1349.805
#258	DLX6	11	13	24	2293.443
#259	IRF5	11	10	21	300.639
#260	RXRB	11	20	31	805.377
#261	ARNTL2	11	17	28	2099.279
#262	ZGPAT	11	17	28	1994.464
#263	HOXA4	11	17	28	1703.306
#264	HOXA1	11	14	25	1104.035
#265	ALS2CR8	11	13	24	787.487
#266	SP140	11	13	24	1410.175
#267	TCEAL1	11	16	27	777.147
#268	SIM2	11	15	26	2134.387
#269	NPAS2	11	14	25	930.527
#270	HOXB1	10	12	22	1594.541
#271	SIM1	10	18	28	1940.326
#272	MYT1L	10	13	23	548.779
#273	EGR3	10	9	19	460.001
#274	FOXD2	10	14	24	808.744
#275	BATF3	10	20	30	2491.839
#276	TEAD4	10	11	21	567.697
#277	STAT6	10	15	25	492.391
#278	PROX1	10	12	22	715.743
#279	HOXB7	10	16	26	1144.464
#280	TFAP4	10	17	27	784.376
#281	ZNF165	10	16	26	717.207
#282	BLZF1	10	13	23	1286.849
#283	ZNF132	10	12	22	849.628
#284	ZNF434	10	13	23	1295.074
#285	NR4A2	10	12	22	317.049
#286	OVOL1	10	18	28	941.178
#287	LEF1	10	17	27	1023.04
#288	NFATC1	10	19	29	1308.298
#289	NKX2-5	9	18	27	2537.555
#290	TFDP3	9	18	27	772.297
#291	DLX2	9	15	24	993.629
#292	HINFP	9	16	25	826.119
#293	ETV2	9	12	21	821.566
#294	NFIX	9	16	25	1208.453
#295	PDX1	9	14	23	1405.642
#296	ZNF155	9	14	23	816.563
#297	ASCL1	9	20	29	3719.004
#298	TBX5	9	15	24	1339.181
#299	RBPJL	9	19	28	2404.48
#300	BRD8	9	19	28	911.591
#301	SOX5	9	16	25	703.779
#302	ONECUT2	9	14	23	1709.838
#303	ALX4	9	13	22	582.798
#304	RXRA	9	11	20	292.985
#305	NKX6-1	9	17	26	1090.871
#306	FOXL2	9	15	24	781.865
#307	ISL1	9	23	32	1557.363
#308	PEG3	9	16	25	1397.314
#309	RCAN1	9	11	20	431.643
#310	HOXA7	9	13	22	1035.797
#311	ARNT2	9	23	32	1236.729
#312	IRF4	9	15	24	1437.846
#313	HOXD1	9	16	25	3145.936
#314	FOXO4	8	13	21	1211.467
#315	ZNF81	8	19	27	6447.688
#316	PTH	8	18	26	1878.595
#317	BNC1	8	12	20	491.489
#318	RORB	8	14	22	723.073
#319	HEY1	8	14	22	562.94
#320	ZNF639	8	21	29	1701.661
#321	MEF2C	8	14	22	1017.261
#322	NR3C2	8	17	25	898.179
#323	TCF3	8	15	23	383.124
#324	TBX2	8	16	24	804.84
#325	ESR2	8	15	23	549.548
#326	TBX10	8	13	21	1107.632
#327	NKX2-8	8	12	20	795.726
#328	E2F1	8	17	25	853.856
#329	EN2	8	21	29	1400.673
#330	T	8	13	21	847.001
#331	ZNF202	8	17	25	533.547
#332	HOXD3	8	16	24	2569.093
#333	NKX3-1	8	18	26	1162.003
#334	NKX2-1	8	15	23	1141.932
#335	TSHZ2	8	12	20	827.305
#336	FOXG1	8	15	23	888.9
#337	PAX7	8	15	23	2284.463
#338	ZNF215	8	16	24	361.395
#339	NR4A3	8	11	19	262.797
#340	RB1	8	15	23	762.75
#341	ELF5	8	19	27	1056.5
#342	MMP14	8	16	24	545.098
#343	SP4	7	17	24	575.292
#344	ZIC1	7	16	23	1021.548
#345	ESRRG	7	20	27	1283.043
#346	PLAG1	7	14	21	1111.708
#347	CUX2	7	19	26	1216.08
#348	E2F8	7	17	24	1202.269
#349	TCF21	7	19	26	1055.284
#350	FOXD1	7	14	21	1199.134
#351	HOXB2	7	11	18	926.103
#352	SCAND2	7	16	23	1180.874
#353	ZNF174	7	18	25	367.409
#354	ELK1	7	16	23	306.984
#355	SIX3	7	17	24	1357.71
#356	THRA	7	17	24	347.12
#357	SMAD3	7	17	24	419.419
#358	HOXD13	7	19	26	729.251
#359	NR1I2	7	14	21	567.901
#360	TAF1B	7	12	19	754.529
#361	TSC22D3	7	15	22	1249.793
#362	CDKN2A	7	16	23	901.982
#363	FOXP3	7	12	19	1300.998
#364	HR	7	18	25	731.188
#365	MAFF	7	13	20	281.071
#366	ELK3	7	17	24	1378.971
#367	HOXB9	7	16	23	866.717
#368	PAX6	7	16	23	339.519
#369	ZFP37	7	16	23	795.94
#370	TP73	6	19	25	517.742
#371	ZNF643	6	15	21	825.077
#372	HNF1A	6	18	24	854.334
#373	SOX2	6	18	24	485.74
#374	TFAP2B	6	18	24	319.433
#375	SRF	6	14	20	588.426
#376	NR2E1	6	16	22	866.664
#377	ZNF3	6	15	21	919.725
#378	CRX	6	12	18	414.495
#379	PAX3	6	17	23	2772.468
#380	TCF7	6	13	19	1066.285
#381	IRX4	6	15	21	731.354
#382	PBX3	6	10	16	1110.394
#383	LMX1B	6	21	27	1416.465
#384	ZNF323	6	14	20	929.965
#385	TLX2	6	17	23	495.679
#386	VENTX	6	12	18	265.649
#387	GAS7	6	19	25	706.909
#388	PITX1	6	19	25	733.25
#389	ZNF80	6	17	23	564.784
#390	MYF5	6	20	26	1440.951
#391	KDM5B	6	19	25	531.822
#392	EMX1	6	21	27	1652.947
#393	SLC26A3	6	21	27	679.241
#394	EPAS1	6	17	23	508.1
#395	KLF5	6	20	26	1103.329
#396	E2F2	6	12	18	495.413
#397	POU4F3	6	23	29	1356.093
#398	HNF4G	6	11	17	269.474
#399	HAND1	6	14	20	1440.022
#400	NEUROD1	6	15	21	832.724
#401	HOXA11	6	16	22	186.566
#402	CREM	6	17	23	1200.957
#403	DMRT1	6	12	18	728.624
#404	HESX1	6	15	21	496.793
#405	REST	6	20	26	958.098
#406	ZNF154	6	17	23	1159.101
#407	FOXD3	5	19	24	489.399
#408	TRIM25	5	18	23	418.284
#409	LHX1	5	17	22	446.847
#410	HOXB3	5	19	24	1366.571
#411	ATF5	5	16	21	778.663
#412	HOXB8	5	14	19	450.485
#413	POU3F1	5	14	19	1231.704
#414	CBFB	5	13	18	152.13
#415	RARB	5	13	18	973.447
#416	POU3F4	5	22	27	577.364
#417	GABPB1	5	19	24	661.676
#418	CEBPE	5	12	17	1079.078
#419	TSC22D2	5	22	27	1152.496
#420	PPARA	5	14	19	513.775
#421	CREB5	5	21	26	759.241
#422	SALL1	5	19	24	965.222
#423	GATA1	5	20	25	953.614
#424	PAX8	5	14	19	545.508
#425	GATA2	5	13	18	1282.438
#426	SOX30	5	14	19	1533.915
#427	MXD1	5	14	19	668.725
#428	HES1	5	12	17	409.317
#429	HOXA10	5	18	23	573.858
#430	CITED1	5	16	21	1294.255
#431	ZNF157	5	21	26	647.839
#432	NPAS1	5	18	23	495.033
#433	SATB2	5	17	22	697.493
#434	ZHX3	5	17	22	415.166
#435	ZSCAN2	5	10	15	441.525
#436	MTA2	4	18	22	452.992
#437	GATA4	4	17	21	602.827
#438	NR0B1	4	18	22	485.115
#439	EGR4	4	15	19	676.822
#440	SCML1	4	20	24	366.758
#441	POU6F2	4	16	20	158.382
#442	PHF1	4	12	16	407.67
#443	NR5A2	4	22	26	365.349
#444	POU2F3	4	20	24	338.845
#445	MLXIPL	4	13	17	213.904
#446	TADA2A	4	20	24	272.19
#447	LZTS1	4	15	19	371.578
#448	GCM1	4	15	19	1224.642
#449	NRL	4	20	24	487.913
#450	ZNF236	4	18	22	673.897
#451	FOSL2	4	16	20	362.942
#452	SOX11	4	18	22	659.628
#453	FOSL1	4	14	18	314.277
#454	CREBZF	4	20	24	779.064
#455	NANOG	4	17	21	975.38
#456	PPARD	4	16	20	368.273
#457	ELF4	4	17	21	597.306
#458	LHX2	4	15	19	568.433
#459	NFE2	4	17	21	502.235
#460	ZNF135	4	12	16	319.139
#461	MNX1	4	16	20	503.092
#462	SNAPC5	4	9	13	610.221
#463	FOXA2	4	16	20	556.895
#464	PRDM2	4	15	19	366.224
#465	DBP	4	12	16	609.822
#466	POU1F1	4	19	23	386.402
#467	BARX1	4	14	18	351.238
#468	TBX6	3	17	20	463.187
#469	RUNX1	3	20	23	293.947
#470	STRN3	3	18	21	204.954
#471	POU3F3	3	17	20	376.045
#472	ST18	3	17	20	344.094
#473	TAL1	3	20	23	586.684
#474	TAF13	3	19	22	369.018
#475	PITX2	3	18	21	209.322
#476	STAT2	3	16	19	440.54
#477	TEF	3	21	24	355.58
#478	RFXAP	3	17	20	272.915
#479	FOXH1	3	20	23	475.286
#480	RERE	3	17	20	300.488
#481	FOXJ1	3	18	21	751.846
#482	NFATC4	2	17	19	276.507
#483	ETV4	2	16	18	181.683
#484	FOXC2	2	17	19	742.316
#485	POU4F1	2	13	15	289.331
#486	SRY	2	18	20	380.52
#487	MSX2	2	16	18	229.831
#488	ATOH1	2	15	17	461.963
#489	HOXC13	2	13	15	153.324
#490	GBX2	2	13	15	963.844
#491	CBFA2T2	2	14	16	261.716
#492	ARID3A	2	17	19	173.632
#493	MYCN	1	16	17	81.808
#494	TBX1	1	16	17	144.714
#495	GSC2	1	21	22	254.056
#496	SIX1	1	20	21	230.762
#497	C11orf9	1	17	18	87.075
#498	POU3F2	1	14	15	47.486
#499	ZNF287	0	20	20	0
#500	MEF2D	0	16	16	0