Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MAFF	168	1	169	361.9
#2	GATA3	144	3	147	1307.624
#3	TEAD4	89	1	90	16.565
#4	ZEB1	84	7	91	7827.037
#5	TSC22D3	82	2	84	49.986
#6	FOS	65	6	71	1998.186
#7	MXD1	63	8	71	1944.375
#8	NR2F2	62	4	66	2166.95
#9	KLF4	61	5	66	668.193
#10	PRDM2	55	7	62	2047.217
#11	TSC22D1	49	5	54	6320.572
#12	SATB1	43	7	50	1679.717
#13	SOX9	43	5	48	6052.945
#14	NFE2L1	39	7	46	1247.148
#15	GTF2IRD1	39	8	47	4761.004
#16	FOXC1	38	11	49	9337.582
#17	ZNF394	37	7	44	1265.994
#18	MSRB2	37	5	42	5888.88
#19	SP3	36	3	39	91.287
#20	BTG2	36	4	40	273.783
#21	BACH1	35	10	45	7029.288
#22	SIX1	34	8	42	827.778
#23	NR3C1	34	9	43	14343.384
#24	EPAS1	34	8	42	3916.504
#25	TRIM22	34	5	39	1222.584
#26	RELB	33	7	40	5956.103
#27	IRX3	32	5	37	1592.554
#28	CITED2	32	8	40	7071.664
#29	NR4A2	30	9	39	1428.79
#30	TFAP2C	28	4	32	64.824
#31	CEBPD	26	4	30	105.937
#32	SCML1	25	9	34	689.693
#33	KLF2	24	5	29	608.754
#34	RUNX2	24	5	29	756.82
#35	ETS1	23	6	29	3644.154
#36	NR2F6	22	7	29	825.532
#37	JUNB	21	2	23	25.035
#38	ZNF232	21	7	28	184.506
#39	MTA3	20	11	31	11307.212
#40	KDM5A	19	8	27	1226.468
#41	SIX4	19	8	27	819.771
#42	PBX3	18	7	25	3244.937
#43	TCFL5	18	6	24	3724.214
#44	ZFP36L1	17	7	24	897.51
#45	HHEX	17	9	26	8506.358
#46	NFIL3	17	9	26	566.925
#47	PURA	17	7	24	121.734
#48	SOX4	17	9	26	8199.099
#49	STRN3	16	5	21	380.79
#50	ZXDC	16	11	27	1293.668
#51	NR1H2	16	8	24	990.899
#52	TCF7L2	16	8	24	3666.989
#53	MEIS2	16	9	25	2173.977
#54	ZSCAN18	16	8	24	1017.035
#55	STAT5A	15	9	24	779.968
#56	ZNF238	15	6	21	346.689
#57	MSX1	14	8	22	115.804
#58	IRF7	14	6	20	279.924
#59	FOSL2	14	2	16	1898.74
#60	TEAD2	14	9	23	557.565
#61	PPARG	14	5	19	382.01
#62	SMAD3	13	6	19	410.211
#63	HES1	13	8	21	373.754
#64	RUNX1	13	8	21	2468.173
#65	TAF4	13	11	24	1056.618
#66	RUNX3	13	7	20	243.078
#67	IRF9	13	6	19	624.858
#68	KLF5	12	5	17	312.767
#69	FOXK2	12	10	22	11855.792
#70	RXRA	12	10	22	413.06
#71	LMO4	12	6	18	796.261
#72	HMGA2	11	6	17	437.134
#73	CNOT8	11	9	20	1556.023
#74	DDIT3	11	11	22	3031.983
#75	JUN	11	7	18	4797.519
#76	HLF	11	2	13	111.886
#77	GLIS2	11	7	18	730.889
#78	STAT3	11	11	22	212.129
#79	OVOL1	10	4	14	313.242
#80	ONECUT2	10	7	17	357.082
#81	TCF4	10	3	13	159.558
#82	CREB3L4	10	6	16	207.278
#83	THRB	10	10	20	6028.466
#84	TCF19	10	9	19	942.873
#85	REL	10	12	22	2950.766
#86	ETV5	10	7	17	193.244
#87	NPAS2	10	4	14	958.302
#88	PURB	10	10	20	258.273
#89	STAT1	10	11	21	938.501
#90	AFF1	10	9	19	7159.931
#91	EHF	10	6	16	621.433
#92	FOSB	9	3	12	31.818
#93	SLC2A4RG	9	14	23	11040.321
#94	ADNP2	9	6	15	545.459
#95	ZNF165	9	10	19	2310.826
#96	FOXN3	9	9	18	606.377
#97	HOXA5	9	6	15	519.484
#98	FOSL1	9	5	14	1361.655
#99	TFDP1	9	6	15	87.867
#100	GATA2	9	8	17	362.827
#101	FOXA1	9	8	17	641.209
#102	TEAD1	9	8	17	645.337
#103	HOXB7	9	6	15	273.146
#104	IRF8	9	5	14	437.47
#105	CUX1	9	7	16	7343.653
#106	PPARD	8	12	20	6389.877
#107	ZEB2	8	4	12	283.982
#108	IRF1	8	2	10	265.568
#109	NFIB	8	13	21	378.167
#110	MSX2	8	6	14	630.895
#111	ZIC2	8	5	13	139.575
#112	SMAD9	8	7	15	186.623
#113	CSRNP1	8	8	16	3429.186
#114	CTNNB1	8	5	13	77.291
#115	FOXO1	8	8	16	309.191
#116	CBFA2T3	8	3	11	44.541
#117	SATB2	8	9	17	1186.794
#118	TFEB	8	10	18	553.359
#119	HCLS1	7	3	10	36.215
#120	FOXD1	7	12	19	198.513
#121	LASS6	7	12	19	471.339
#122	FOXQ1	7	7	14	1432.424
#123	HOXB3	7	9	16	414.603
#124	BHLHE40	7	8	15	1537.185
#125	TP53	7	5	12	165.945
#126	PHF1	7	10	17	309.156
#127	RFXAP	7	11	18	444.502
#128	ZNF274	7	6	13	2146.712
#129	HMGB1	7	4	11	17.651
#130	SOX2	7	8	15	458.621
#131	ARID4A	7	8	15	632.679
#132	ZNF193	7	7	14	1169.57
#133	ZIC1	6	9	15	244.344
#134	ARNTL	6	9	15	355.128
#135	ETV6	6	8	14	80.108
#136	NR1H4	6	3	9	126.368
#137	SALL1	6	10	16	350.618
#138	C5orf41	6	3	9	30.474
#139	KDM5B	6	11	17	611.726
#140	ZKSCAN1	6	14	20	1443.996
#141	PPARA	6	9	15	2803.883
#142	MNX1	6	5	11	213.082
#143	ZNF367	6	12	18	314.685
#144	AEBP1	6	3	9	82.932
#145	RCAN1	6	8	14	1023.755
#146	SMAD1	6	8	14	314.234
#147	ESX1	6	5	11	686.679
#148	ELF1	6	6	12	456.832
#149	NR4A3	6	7	13	1884.309
#150	VAV1	6	7	13	1779.133
#151	NFKB1	6	7	13	2832.537
#152	TBX2	6	8	14	343.916
#153	JUND	6	9	15	1615.794
#154	SUPT4H1	6	6	12	188.186
#155	HOXB6	6	5	11	164.347
#156	ASCL1	6	2	8	50.799
#157	SIX5	6	10	16	452.609
#158	PLAGL2	6	10	16	276.953
#159	FOXM1	6	10	16	1215.128
#160	FOXA3	5	7	12	301.072
#161	CEBPA	5	3	8	1726.212
#162	EGR3	5	7	12	119.159
#163	C11orf9	5	2	7	4.739
#164	TFCP2	5	9	14	914.859
#165	HES6	5	6	11	591.249
#166	FOXP4	5	8	13	4494.731
#167	MLXIPL	5	8	13	274.992
#168	L3MBTL4	5	7	12	160.882
#169	MYCL1	5	9	14	148.741
#170	ZNF217	5	8	13	233.024
#171	SMAD5	5	15	20	927.413
#172	ZFPM1	5	12	17	3310.788
#173	PAX6	5	5	10	154.337
#174	TCEAL1	5	9	14	263.495
#175	ZNF256	5	7	12	220.863
#176	ZBTB38	5	5	10	359.465
#177	FOXO6	5	7	12	489.513
#178	CCRN4L	5	9	14	186.587
#179	FOXL1	5	5	10	51.855
#180	ZXDA	5	8	13	55.192
#181	CBL	5	6	11	113.611
#182	HMGA1	5	6	11	870.81
#183	HNF1A	5	9	14	340.535
#184	ELF4	5	11	16	132.925
#185	MEF2D	5	8	13	233.22
#186	BATF	5	8	13	184.848
#187	SCAND1	4	11	15	308.517
#188	HOXB4	4	6	10	290.065
#189	FOXC2	4	9	13	92.396
#190	IRF4	4	7	11	295.747
#191	ZSCAN1	4	8	12	554.501
#192	FOXA2	4	7	11	168.329
#193	KLF6	4	14	18	5933.76
#194	BRD8	4	9	13	138.138
#195	AFF4	4	7	11	44.315
#196	HOXD1	4	5	9	1564.718
#197	HOXB9	4	7	11	141.561
#198	PAX8	4	4	8	95.025
#199	ASCL2	4	4	8	73.432
#200	NEUROD1	4	7	11	473.714
#201	ZNF268	4	11	15	187.39
#202	MEIS3P1	4	8	12	2504.297
#203	ZFP36L2	4	11	15	3740.361
#204	SREBF1	4	6	10	491.398
#205	ATF6B	4	7	11	97.034
#206	MTF1	4	8	12	405.816
#207	ISL2	4	7	11	44.717
#208	HR	4	5	9	390.081
#209	UHRF1	4	11	15	1851.347
#210	E2F7	4	13	17	277.405
#211	PGR	4	4	8	84.38
#212	PLSCR1	4	2	6	9.48
#213	VTN	4	8	12	2504.934
#214	AR	4	7	11	135.773
#215	SOX7	4	8	12	125.818
#216	CREBBP	4	5	9	148.534
#217	TCF12	4	9	13	839.838
#218	ZFHX3	4	11	15	359.227
#219	NFE2L3	4	8	12	104.707
#220	ZIC5	4	5	9	440.418
#221	BLZF1	4	9	13	351.767
#222	ELF3	4	9	13	182.092
#223	HIRA	4	8	12	75.563
#224	ARNT	4	8	12	132.066
#225	ENO1	3	8	11	1243.53
#226	ETV4	3	5	8	43.408
#227	PROX1	3	10	13	220.599
#228	TRPS1	3	6	9	29.403
#229	NR2F1	3	6	9	827.314
#230	HOXA3	3	8	11	108.62
#231	TBX3	3	10	13	121.251
#232	HOXB8	3	6	9	229.761
#233	HOXB2	3	1	4	1.392
#234	TFAP2A	3	7	10	1279.957
#235	MEIS1	3	5	8	49.679
#236	ZNF24	3	6	9	159.819
#237	CREB3L2	3	6	9	141.632
#238	MEF2C	3	6	9	624.658
#239	PITX1	3	2	5	56.192
#240	RORA	3	11	14	202.128
#241	HOXD10	3	5	8	90.273
#242	IRF5	3	3	6	14.451
#243	NFATC2	3	11	14	707.71
#244	MYCN	3	7	10	104.695
#245	HOXC12	3	5	8	307.8
#246	SOX30	3	8	11	122.185
#247	TULP4	3	9	12	3929.285
#248	TFE3	3	5	8	217.912
#249	E2F6	3	6	9	370.665
#250	ZNF148	3	11	14	64.039
#251	EGR2	3	5	8	46.199
#252	NFX1	3	8	11	405.764
#253	ZNF41	3	7	10	63.851
#254	KLF7	3	8	11	171.675
#255	TEAD3	3	12	15	213.43
#256	PAX7	3	7	10	396.671
#257	ZNF175	3	6	9	76.802
#258	KLF12	3	11	14	148.661
#259	GAS7	3	11	14	164.19
#260	E2F5	3	14	17	182.138
#261	CREBZF	3	9	12	793.024
#262	TEF	3	10	13	181.123
#263	IRX4	3	5	8	122.439
#264	NFKB2	3	9	12	89.328
#265	RAX2	3	7	10	735.733
#266	CSDA	3	7	10	139.968
#267	ZNF33A	3	8	11	146.93
#268	ARNT2	3	8	11	66.182
#269	NFATC3	3	9	12	3349.168
#270	HOXC4	3	5	8	109.272
#271	NFE2	2	6	8	14.054
#272	HEY2	2	5	7	126.09
#273	RARA	2	9	11	136.684
#274	FOXN4	2	5	7	176.469
#275	SOX8	2	8	10	96.84
#276	NR1D2	2	15	17	109.828
#277	CREB5	2	6	8	43.245
#278	EGR1	2	9	11	265.415
#279	LASS2	2	9	11	18.99
#280	IRX2	2	3	5	159.941
#281	SPIB	2	4	6	110.058
#282	ST18	2	5	7	116.427
#283	HOXC13	2	5	7	95.861
#284	ZNF483	2	8	10	180.108
#285	POU4F1	2	4	6	41.142
#286	MYT1L	2	5	7	86.895
#287	ZNF92	2	8	10	195.256
#288	ZNF628	2	7	9	744.444
#289	ELK4	2	6	8	170.621
#290	HOXB5	2	6	8	114.824
#291	KLF1	2	4	6	28.657
#292	FOXD4	2	6	8	296.902
#293	TAL1	2	5	7	41.281
#294	CREM	2	5	7	93.246
#295	HOXA13	2	5	7	65.009
#296	DLX1	2	6	8	16.85
#297	SOX12	2	8	10	102.011
#298	E2F4	2	5	7	20.628
#299	NR6A1	2	6	8	12.483
#300	CBFA2T2	2	8	10	28.209
#301	GLI3	2	11	13	41.445
#302	HDX	2	6	8	49.232
#303	LMX1A	2	7	9	51.614
#304	ZNF81	2	3	5	66.139
#305	STAT5B	2	9	11	110.828
#306	HNF4A	2	6	8	31.049
#307	MLX	2	6	8	138.923
#308	MBD1	2	9	11	613.498
#309	ELK3	2	11	13	125.086
#310	TARDBP	2	6	8	53.139
#311	TRERF1	2	3	5	17.468
#312	RBCK1	2	6	8	41.016
#313	ETV1	2	6	8	48.189
#314	SOLH	2	5	7	91.427
#315	IKZF1	2	6	8	1082.796
#316	ETV3	2	7	9	198.652
#317	SNAI2	2	4	6	47.75
#318	TFAP2B	2	7	9	177.541
#319	ALS2CR8	2	6	8	734.896
#320	PBX4	2	8	10	52.149
#321	ZNF33B	2	12	14	75.283
#322	ZNF207	2	9	11	36.425
#323	SP1	2	13	15	226.143
#324	GATA6	2	12	14	2053.668
#325	RERE	2	7	9	228.503
#326	TCF25	2	6	8	49.26
#327	BCL3	2	11	13	68.189
#328	TBX5	2	9	11	262.648
#329	NANOGNB	2	10	12	142.533
#330	ESR1	2	4	6	38.714
#331	E2F2	2	8	10	154.135
#332	IRX1	2	7	9	266.794
#333	PCGF2	2	11	13	938.882
#334	ZNF135	2	6	8	113.026
#335	CDKN2A	2	8	10	78.062
#336	ZFHX4	1	4	5	26.083
#337	SOX13	1	9	10	29.727
#338	NFYA	1	9	10	38.625
#339	MITF	1	6	7	14.005
#340	NFATC1	1	5	6	5.17
#341	BCL6	1	10	11	102.311
#342	NR1I2	1	7	8	49.479
#343	ZBTB17	1	8	9	8.532
#344	LHX2	1	4	5	26.227
#345	ISX	1	11	12	12.896
#346	ZNF80	1	7	8	66.205
#347	SRY	1	7	8	23.613
#348	FOXJ2	1	7	8	87.113
#349	POU5F2	1	8	9	47.198
#350	HOXD8	1	10	11	103.283
#351	MESP2	1	14	15	56.56
#352	MESP1	1	5	6	16.235
#353	SIM1	1	5	6	105.189
#354	TP73	1	7	8	52.199
#355	PEG3	1	6	7	44.667
#356	BNC1	1	4	5	46.774
#357	ZHX2	1	6	7	33.203
#358	ARID3A	1	8	9	50.11
#359	SMAD2	1	8	9	37.669
#360	GATA1	1	4	5	11.959
#361	FOXP2	1	7	8	15.286
#362	C12orf28	1	8	9	161.918
#363	MAF	1	9	10	1.167
#364	POU2F2	1	6	7	4.643
#365	ARNTL2	1	7	8	16.162
#366	AHCTF1	1	6	7	54.205
#367	GLIS3	1	4	5	37.093
#368	FOXO3	1	6	7	12.068
#369	SIN3A	1	6	7	11.486
#370	KCNH8	1	4	5	3.412
#371	HOPX	1	4	5	2.7
#372	C1orf85	1	10	11	57.799
#373	ZNF85	1	9	10	46.298
#374	BHLHE41	1	4	5	5.5
#375	MEF2A	1	11	12	10.896
#376	ZNF215	1	5	6	17.833
#377	RCOR2	1	10	11	76.948
#378	NFE2L2	1	14	15	118.572
#379	GSX1	1	4	5	80.022
#380	NFIX	1	8	9	45.583
#381	ESRRB	1	5	6	15.046
#382	ATF3	1	4	5	16.251
#383	HOXA9	1	3	4	4.343
#384	MEIS3	1	9	10	28.241
#385	TSC22D4	1	6	7	86.704
#386	HOXB13	1	10	11	165.373
#387	IRX5	1	3	4	5.2
#388	ZKSCAN3	1	6	7	335.459
#389	GSC	1	10	11	523.915
#390	TGIF1	1	12	13	33.715
#391	MECOM	1	8	9	35.7
#392	TBX1	1	7	8	100.789
#393	HNF4G	1	8	9	25.57
#394	RHOXF1	1	6	7	43.438
#395	SPDEF	1	9	10	31.35
#396	ZSCAN23	1	9	10	304.555
#397	NFIA	1	9	10	53.626
#398	HNF1B	1	6	7	23.728
#399	FLI1	1	10	11	22.527
#400	GTF2H2	1	16	17	53.707
#401	NFIC	1	9	10	56.336
#402	TBX20	1	6	7	241.568
#403	POU6F1	1	3	4	60.758
#404	KLF17	1	9	10	157.671
#405	EBF1	1	3	4	20.146
#406	CEBPE	1	6	7	27.143
#407	HSF5	1	5	6	15.344
#408	ZNF90	1	3	4	32.783
#409	DLX3	1	8	9	71.029
#410	FOXK1	1	10	11	24.823
#411	PBX1	1	4	5	20.866
#412	KLF11	1	11	12	78.566
#413	SOX6	1	8	9	9.41
#414	ERG	1	5	6	22.539
#415	IRF6	1	9	10	5.111
#416	SPEN	1	17	18	133.401
#417	SNAI3	1	4	5	13.955
#418	ZNF71	1	8	9	63.802
#419	ZNF496	1	6	7	28.564
#420	FOXP1	1	7	8	27.749
#421	CTBP1	1	4	5	315.369
#422	ZNF396	1	9	10	31.136
#423	HOXA7	1	8	9	9.094
#424	KLF16	1	11	12	63.621
#425	BACH2	1	6	7	44.437
#426	LZTS1	1	4	5	27.275
#427	MAFG	0	9	9	0
#428	PRDM1	0	6	6	0
#429	RUNX1T1	0	6	6	0
#430	NR1I3	0	3	3	0
#431	ZNF83	0	5	5	0
#432	SLC26A3	0	8	8	0
#433	MLL	0	8	8	0
#434	HOXC9	0	7	7	0
#435	RORC	0	9	9	0
#436	HOXA2	0	6	6	0
#437	TSHZ2	0	9	9	0
#438	TWIST2	0	5	5	0
#439	ZSCAN20	0	7	7	0
#440	DLX6	0	7	7	0
#441	POU2F1	0	15	15	0
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#449	HOXD4	0	7	7	0
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#451	GRHL2	0	9	9	0
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#454	MAX	0	7	7	0
#455	SUPT6H	0	8	8	0
#456	TFEC	0	4	4	0
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#458	TFDP2	0	10	10	0
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#460	ZFP42	0	7	7	0
#461	ZNF75D	0	7	7	0
#462	ZSCAN4	0	4	4	0
#463	TP63	0	11	11	0
#464	FOXL2	0	8	8	0
#465	SP140	0	4	4	0
#466	TFAP2E	0	11	11	0
#467	MYT1	0	7	7	0
#468	HIF3A	0	6	6	0
#469	SPI1	0	11	11	0
#470	MMP14	0	7	7	0
#471	MGA	0	7	7	0
#472	ZNF169	0	8	8	0
#473	RBPJ	0	9	9	0
#474	WT1	0	7	7	0
#475	GATA4	0	7	7	0
#476	LHX9	0	7	7	0
#477	MYNN	0	6	6	0
#478	ZNF446	0	10	10	0
#479	PGBD1	0	8	8	0
#480	NEUROD2	0	4	4	0
#481	NFYC	0	7	7	0
#482	LHX4	0	4	4	0
#483	KLF15	0	10	10	0
#484	SCAND3	0	17	17	0
#485	ZNF93	0	7	7	0
#486	ZNF438	0	9	9	0
#487	SOX5	0	6	6	0
#488	ATF2	0	5	5	0
#489	ZNF117	0	8	8	0
#490	ZFPM2	0	4	4	0
#491	FOXR2	0	7	7	0
#492	MIXL1	0	6	6	0
#493	ARX	0	6	6	0
#494	SEBOX	0	7	7	0
#495	ZSCAN10	0	9	9	0
#496	SIM2	0	4	4	0
#497	BCL11B	0	8	8	0
#498	MKX	0	7	7	0
#499	NR5A2	0	11	11	0
#500	MZF1	0	7	7	0