Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	POU5F1B	56	1	57	8.155
#2	MLLT10	52	1	53	505.876
#3	RARA	52	4	56	2532.707
#4	FOXP3	48	2	50	1010.441
#5	HIF3A	48	8	56	184.501
#6	HMX1	47	7	54	91.009
#7	SCAND2	46	9	55	3372.51
#8	CNBP	46	12	58	2050.052
#9	ARID4A	44	7	51	578.841
#10	E2F4	43	4	47	38.445
#11	SOX15	43	8	51	1865.473
#12	MMP14	42	9	51	840.32
#13	ATF5	42	8	50	145.878
#14	ZNF207	41	7	48	4137.301
#15	TCF15	39	6	45	772.207
#16	GAS7	39	17	56	1159.29
#17	GTF2H3	39	3	42	1499.492
#18	NFATC4	38	7	45	5163.848
#19	MTF1	38	7	45	243.169
#20	YY1	37	9	46	686.553
#21	MEF2D	37	9	46	175.742
#22	SCML2	37	8	45	1143.942
#23	ZNF287	36	7	43	305.015
#24	ZNF277	36	8	44	3168.189
#25	TFAM	35	12	47	2832.099
#26	HMGB1	34	10	44	1384.523
#27	NFATC1	33	12	45	2618.929
#28	TRIM25	33	13	46	976.694
#29	SHOX	33	12	45	196.892
#30	SOX2	31	13	44	608.87
#31	LASS6	31	12	43	722.536
#32	ATF2	31	16	47	2456.784
#33	ESRRA	30	15	45	1250.135
#34	ZNF157	30	11	41	1847.256
#35	HOXB5	30	10	40	606.101
#36	HOXA10	30	6	36	175.403
#37	ETV5	29	15	44	2237.357
#38	SMAD6	29	10	39	587.777
#39	SNAPC2	29	9	38	306.45
#40	NFIX	29	11	40	1491.193
#41	HR	28	11	39	775.931
#42	SMAD2	28	12	40	1448.465
#43	GLI3	28	12	40	1051.512
#44	STAT6	28	8	36	949.527
#45	PAX8	28	15	43	1285.985
#46	TFE3	28	15	43	1689.473
#47	XBP1	28	6	34	492.149
#48	NR6A1	27	13	40	866.147
#49	ZNF93	27	10	37	1321.919
#50	TSC22D1	27	17	44	1763.17
#51	GABPB1	27	11	38	2224.887
#52	TP53	27	17	44	4376.25
#53	TFAP2A	27	15	42	1304.01
#54	NR4A1	26	16	42	1170.13
#55	NFATC3	26	14	40	535.027
#56	RBPJ	26	14	40	1589.618
#57	CREB3L2	26	7	33	1141.951
#58	E2F1	26	12	38	290.833
#59	ATF3	25	3	28	339.66
#60	MEF2A	25	15	40	1692.085
#61	TAF7	25	12	37	2329.369
#62	FOXC1	25	9	34	1045.557
#63	EDF1	25	15	40	557.365
#64	SLC30A9	25	10	35	588.722
#65	POU2F2	24	13	37	726.316
#66	TAF10	24	13	37	684.427
#67	PBX1	24	15	39	1489.438
#68	TCF7	24	5	29	2196.967
#69	HNRNPK	24	20	44	1390.363
#70	ESR2	24	12	36	1220.101
#71	ZHX2	23	17	40	2016.02
#72	IRF7	23	16	39	1408.058
#73	MBD1	23	15	38	1446.109
#74	SPDEF	23	11	34	1043.503
#75	JUN	23	12	35	1731.009
#76	CTBP1	23	6	29	1328.186
#77	VAV1	23	12	35	1819.245
#78	NFYA	22	7	29	620.311
#79	LASS2	22	15	37	1103.232
#80	CBFA2T2	22	13	35	326.908
#81	GRHL2	22	12	34	1908.03
#82	CNOT7	22	14	36	1513.112
#83	ENO1	22	8	30	1371.511
#84	SOX4	22	14	36	1524.315
#85	BHLHE40	22	14	36	1380.623
#86	ZSCAN18	21	13	34	1189.792
#87	POU4F2	21	11	32	169.956
#88	ATF1	21	17	38	4032.92
#89	ZNF446	21	10	31	373.425
#90	TRPS1	21	16	37	1088.576
#91	MECOM	21	8	29	1110.794
#92	GABPA	21	19	40	882.485
#93	JUND	21	11	32	1270.787
#94	STRN3	21	9	30	1406.168
#95	TSC22D4	21	10	31	462.078
#96	SREBF2	21	8	29	189.236
#97	RFX5	21	18	39	1514.531
#98	EPAS1	21	15	36	938.245
#99	TRIM28	21	15	36	2026.137
#100	VSX1	20	8	28	712.386
#101	ATF6B	20	11	31	786.122
#102	HOXA4	20	14	34	1003.215
#103	SP3	20	13	33	1372.835
#104	ZNF500	20	13	33	714.928
#105	TWIST1	20	13	33	2000.513
#106	STAT1	20	18	38	803.792
#107	NR2F6	20	21	41	1462.875
#108	CREBBP	20	16	36	2052.417
#109	HSF2	20	13	33	1643.88
#110	ZEB2	19	15	34	1520.025
#111	ZGPAT	19	12	31	1505.689
#112	SNAI2	19	11	30	691.179
#113	MEOX2	19	8	27	1305.14
#114	HMG20B	19	13	32	1817.788
#115	SREBF1	19	12	31	615.851
#116	UBP1	19	15	34	1275.482
#117	ETV1	19	16	35	1018.669
#118	CTCF	19	13	32	938.723
#119	GATA3	19	12	31	754.14
#120	FOXA1	19	8	27	401.174
#121	PAX5	19	10	29	241.013
#122	MEIS3P1	19	20	39	2016.972
#123	ZNF274	19	12	31	4802.683
#124	FOS	18	8	26	640.57
#125	ZNF83	18	14	32	816.656
#126	CBFB	18	15	33	884.764
#127	EHF	18	21	39	1861.527
#128	NFKB2	18	13	31	1285.33
#129	FOXO3	18	16	34	748.268
#130	ZNF189	18	18	36	3829.959
#131	TBX6	18	10	28	154.168
#132	HMGB2	18	19	37	2415.385
#133	CSDA	18	18	36	2087.059
#134	FOXA2	18	14	32	387.998
#135	ZNF236	18	13	31	742.897
#136	HEYL	18	10	28	1172.988
#137	MITF	18	14	32	1057.334
#138	CTNNB1	17	17	34	1562.561
#139	ZNF140	17	18	35	2582.56
#140	TFCP2L1	17	14	31	1655.364
#141	BLZF1	17	15	32	3070.944
#142	MZF1	17	19	36	1822.444
#143	HOXA5	17	9	26	1222.001
#144	ZSCAN16	17	14	31	434.278
#145	PHOX2B	17	8	25	580.408
#146	GATAD2A	17	9	26	574.695
#147	IRX5	17	12	29	557.183
#148	SP4	17	5	22	496.643
#149	MLX	17	22	39	7521.628
#150	ATF4	17	18	35	898.557
#151	KLF7	17	11	28	819.001
#152	ZNF24	17	21	38	1642.244
#153	NANOG	17	16	33	1052.439
#154	STAT5A	16	13	29	1426.504
#155	EGR1	16	7	23	777.298
#156	MAFF	16	14	30	585.393
#157	ELK1	16	13	29	422.272
#158	POU4F1	16	19	35	721.882
#159	KLF5	16	12	28	893.505
#160	ST18	16	10	26	842.605
#161	UBN1	16	14	30	1238.609
#162	LMO4	16	16	32	1203.314
#163	NFIL3	16	19	35	1104.928
#164	ZFP36L1	16	13	29	1111.088
#165	NFIB	16	18	34	1611.863
#166	HAND1	16	6	22	279.17
#167	ZBTB17	16	11	27	282.741
#168	FOXD1	16	8	24	701.773
#169	KLF9	16	13	29	906.687
#170	HMBOX1	16	19	35	464.603
#171	TFDP1	16	20	36	2106.541
#172	SMAD1	16	8	24	915.253
#173	BHLHE41	16	12	28	1365.282
#174	ARNTL	16	15	31	1089.05
#175	ADNP	16	20	36	1971.752
#176	KLF6	15	16	31	1092.044
#177	TAF1B	15	8	23	881.044
#178	TULP4	15	14	29	819.923
#179	SUPT4H1	15	17	32	755.038
#180	ZNF434	15	7	22	802.295
#181	ALX1	15	11	26	1008.426
#182	RERE	15	23	38	1590.169
#183	SNAPC4	15	9	24	582.641
#184	PA2G4	15	11	26	480.571
#185	FOXJ2	15	16	31	894.43
#186	HCFC1	15	12	27	1743.583
#187	VDR	15	18	33	1437.516
#188	NFYC	15	15	30	840.487
#189	PFDN1	15	14	29	1250.882
#190	PRRX1	15	16	31	861.481
#191	CITED2	15	13	28	956.407
#192	CEBPB	15	22	37	1956.29
#193	HDAC2	15	18	33	1258.435
#194	SRF	15	12	27	1315.214
#195	NFE2L1	15	13	28	794.555
#196	MYNN	15	16	31	1923.176
#197	ZNF175	15	14	29	572.804
#198	STAT5B	15	11	26	893.319
#199	BTAF1	15	28	43	1807.401
#200	SOX30	15	12	27	729.166
#201	CREB3L1	14	15	29	1593.368
#202	MAF	14	21	35	2262.36
#203	SOX10	14	14	28	1556.253
#204	ZNF238	14	15	29	351.071
#205	ZNF148	14	24	38	484.619
#206	CREM	14	15	29	876.63
#207	KDM5B	14	15	29	2345.048
#208	FBXW7	14	15	29	385.835
#209	TSC22D2	14	10	24	599.647
#210	AHCTF1	14	11	25	1355.277
#211	JUNB	14	13	27	932.274
#212	ZNF281	14	17	31	1273.943
#213	ASCL1	14	4	18	232.146
#214	ZNF3	14	17	31	1544.103
#215	NR3C2	14	12	26	1359.719
#216	FOXJ3	14	14	28	957.058
#217	FOXK2	14	18	32	1902.327
#218	HNF1A	14	11	25	564.45
#219	IRF1	14	9	23	722.752
#220	NR5A2	14	9	23	687.354
#221	CREB1	14	8	22	605.339
#222	BATF3	13	10	23	883.18
#223	AATF	13	9	22	590.261
#224	ZNF268	13	20	33	1480.046
#225	IRF9	13	12	25	1061.652
#226	NR2F1	13	16	29	991.936
#227	PPARD	13	25	38	1874.365
#228	TAF13	13	8	21	513.703
#229	EGR2	13	8	21	413.745
#230	ZSCAN12	13	10	23	273.022
#231	HSF1	13	12	25	972.581
#232	SOX5	13	13	26	740.321
#233	SIM1	13	10	23	607.345
#234	NEUROD2	13	7	20	574.889
#235	HDAC1	13	15	28	731.784
#236	AR	13	13	26	561.625
#237	RCOR1	13	12	25	743.598
#238	NCOR1	13	13	26	971.725
#239	ZHX3	13	9	22	671.92
#240	WNT5A	13	17	30	1616.443
#241	PHF1	13	18	31	914.89
#242	RNF4	13	10	23	970.616
#243	USF2	12	15	27	577.703
#244	HOXB2	12	13	25	1070.347
#245	PLAGL2	12	14	26	614.225
#246	SIX2	12	15	27	1109.876
#247	ZNF444	12	21	33	960.846
#248	TCF12	12	21	33	1316.076
#249	KLF10	12	17	29	1129.517
#250	HCLS1	12	18	30	1217.048
#251	FOXM1	12	14	26	968.848
#252	TGIF1	12	15	27	1048.586
#253	KDM5A	12	18	30	1545.698
#254	ZNF45	12	19	31	711.367
#255	CBL	12	10	22	791.429
#256	C2orf3	12	9	21	1148.02
#257	AFF1	12	17	29	1111.363
#258	HOXC4	12	14	26	797.047
#259	KLF11	12	18	30	1231.19
#260	ELK4	12	11	23	815.25
#261	PGR	12	13	25	987.966
#262	TCF25	12	15	27	1441.764
#263	ZNF135	12	11	23	428.123
#264	RB1	12	24	36	1473.562
#265	ZFHX4	12	18	30	1598.581
#266	SATB1	12	20	32	873.06
#267	ZNF639	12	11	23	487.658
#268	TSC22D3	12	13	25	1217.693
#269	TAL1	12	13	25	1465.236
#270	HNRNPAB	12	12	24	628.45
#271	MTA1	12	13	25	609.227
#272	E2F6	12	16	28	1826.025
#273	NFAT5	12	15	27	1072.916
#274	SOX11	12	27	39	3386.762
#275	NFE2L2	12	11	23	1054.41
#276	HOXD9	12	10	22	1096.402
#277	DLX2	11	20	31	1747.341
#278	SOX9	11	23	34	1835.394
#279	TCF7L1	11	10	21	392.674
#280	SATB2	11	20	31	1316.909
#281	THRA	11	10	21	506.369
#282	ZEB1	11	27	38	1616.438
#283	ZIC1	11	13	24	893.826
#284	TFCP2	11	13	24	643.636
#285	PHTF1	11	12	23	733.286
#286	MSL3	11	20	31	1679.186
#287	EN1	11	8	19	495.861
#288	CEBPD	11	15	26	920.184
#289	BRD8	11	22	33	1257.157
#290	TCF3	11	17	28	2110.625
#291	IRF3	11	14	25	1589.396
#292	ONECUT1	11	14	25	1226.568
#293	MLL	11	18	29	1464.704
#294	HESX1	11	21	32	1002.02
#295	NOLC1	11	18	29	995.686
#296	SNAPC5	11	18	29	281.066
#297	CUX1	11	22	33	1243.287
#298	ZNF187	11	17	28	1369.11
#299	ZNF193	11	13	24	746.827
#300	ELF1	11	13	24	857.763
#301	KLF2	11	18	29	1662.815
#302	IRF2	11	16	27	880.17
#303	TFEC	11	14	25	986.878
#304	SMAD3	11	18	29	1357.098
#305	LZTS1	11	12	23	750.018
#306	ZKSCAN5	11	14	25	409.79
#307	AHR	11	19	30	1054.46
#308	PTTG1	11	18	29	730.325
#309	TFAP2C	11	25	36	1685.077
#310	FOSB	11	23	34	1332.109
#311	TSHZ2	11	17	28	978.6
#312	ZNF131	10	18	28	602.174
#313	HIF1A	10	24	34	2013.708
#314	NR2C1	10	19	29	1367.942
#315	ECSIT	10	15	25	855.875
#316	ELF2	10	19	29	855.915
#317	PLSCR1	10	25	35	1093.29
#318	HOXA2	10	13	23	1341.488
#319	BCL6	10	17	27	1102.21
#320	ZFP36L2	10	17	27	1265.972
#321	RXRA	10	18	28	829.719
#322	MYC	10	14	24	595.222
#323	SMAD4	10	15	25	647.518
#324	ZNF165	10	14	24	758.496
#325	CSRNP3	10	9	19	469.815
#326	CREBL2	10	23	33	1973.871
#327	RUNX3	10	11	21	610.706
#328	RARB	10	8	18	595.746
#329	PBX2	10	15	25	737.193
#330	IRF6	10	19	29	963.069
#331	RORB	10	8	18	352.661
#332	MAFB	10	12	22	626.386
#333	LZTR1	10	14	24	614.583
#334	CBFA2T3	10	8	18	494.174
#335	ALS2CR8	10	13	23	743.091
#336	TCEAL1	10	16	26	793.365
#337	TFDP2	10	18	28	1060.029
#338	ZNF167	10	20	30	915.258
#339	ZNF91	10	13	23	571.81
#340	LHX6	10	11	21	610.888
#341	TBX19	10	13	23	715.614
#342	SIX1	10	12	22	714.865
#343	E2F3	10	19	29	1174.056
#344	LEF1	10	16	26	734.818
#345	YBX1	9	24	33	1030.354
#346	SOX12	9	10	19	476.668
#347	NFYB	9	25	34	2408.363
#348	NR2E1	9	9	18	771.498
#349	SOX13	9	18	27	1094.958
#350	DRAP1	9	12	21	400.213
#351	FOXN2	9	18	27	580.741
#352	ZBTB38	9	19	28	1104.514
#353	NFX1	9	7	16	760.084
#354	CSRNP2	9	15	24	264.266
#355	MAX	9	18	27	734.012
#356	ELF4	9	14	23	803.462
#357	TEAD4	9	19	28	756.624
#358	RELA	9	13	22	419.304
#359	KLF12	9	12	21	767.134
#360	GATA2	9	15	24	526.55
#361	NFE2L3	9	13	22	546.57
#362	ZNF215	9	12	21	609.189
#363	E4F1	9	16	25	658.207
#364	NR1H3	9	11	20	584.601
#365	SP1	9	12	21	607.151
#366	ZNF202	9	19	28	1372.027
#367	HLF	9	11	20	311.135
#368	CIR1	9	16	25	1911.794
#369	NKX2-1	9	7	16	423.964
#370	ESRRG	9	23	32	1328.912
#371	DMRT1	8	11	19	848.703
#372	ZNF75D	8	22	30	1442.207
#373	TCF4	8	26	34	1184.466
#374	TARDBP	8	25	33	1368.462
#375	ETS2	8	16	24	624.824
#376	TAF4	8	15	23	877.456
#377	FOSL2	8	17	25	343.668
#378	RUNX1T1	8	24	32	1888.282
#379	HOXB7	8	10	18	488.27
#380	ZNF217	8	18	26	510.503
#381	PKNOX1	8	14	22	1092.315
#382	TRIM29	8	13	21	551.36
#383	PRDM2	8	16	24	664.83
#384	HOXD3	8	20	28	855.461
#385	MEF2C	8	22	30	1566.554
#386	MNT	8	16	24	672.477
#387	GATA6	8	26	34	1089.36
#388	SIX3	8	11	19	406.513
#389	BTG2	8	19	27	754.365
#390	HES1	8	20	28	619.828
#391	NR3C1	8	24	32	784.689
#392	SALL2	8	17	25	872.912
#393	NKX3-1	8	18	26	1959.965
#394	REXO4	8	14	22	533.741
#395	NPAT	8	16	24	931.421
#396	POU2F1	8	13	21	643.553
#397	TFAP2B	8	22	30	943.589
#398	ERG	8	11	19	421.385
#399	SMAD5	8	22	30	1214.301
#400	NR2F2	7	21	28	720.329
#401	HOXD4	7	14	21	594.214
#402	FOXO1	7	24	31	1433.839
#403	AFF4	7	8	15	789.907
#404	HEY1	7	29	36	2023.42
#405	MEIS2	7	21	28	515.242
#406	ESR1	7	19	26	892.825
#407	RUNX1	7	18	25	607.667
#408	HIRA	7	9	16	379.856
#409	REL	7	16	23	975.605
#410	STAT4	7	7	14	254.874
#411	POU2F3	7	19	26	2307.978
#412	SIM2	7	20	27	1439.656
#413	TCFL5	7	13	20	260.045
#414	ZFPM2	7	15	22	420.384
#415	BCL3	7	13	20	600.021
#416	IRF8	7	18	25	576.926
#417	EGR3	7	14	21	546.033
#418	NR2C2	7	10	17	350.785
#419	TAF4B	7	13	20	1010.211
#420	POU3F2	7	11	18	432.554
#421	DMTF1	7	16	23	1096.89
#422	ATF6	7	15	22	481.604
#423	DLX4	7	22	29	1170.793
#424	ZNF323	7	18	25	869.263
#425	ELF3	7	16	23	478.179
#426	STAT3	7	19	26	780.991
#427	HMGA1	7	13	20	357.408
#428	TEAD1	7	20	27	1113.988
#429	SP140	7	12	19	520.787
#430	ARNT	6	16	22	533.82
#431	ZNF394	6	15	21	963.969
#432	ADNP2	6	24	30	644.827
#433	MSX1	6	20	26	969.129
#434	HMG20A	6	13	19	648.336
#435	FOXF1	6	14	20	635.397
#436	NR4A2	6	11	17	406.21
#437	KLF4	6	20	26	486.437
#438	FLI1	6	22	28	623.099
#439	ELK3	6	14	20	479.044
#440	WT1	6	22	28	745.332
#441	BACH1	6	18	24	761.388
#442	CREBZF	6	16	22	771.014
#443	GTF2IRD1	6	17	23	856.697
#444	ZXDC	6	17	23	714.809
#445	RCAN1	6	23	29	693.918
#446	RORA	6	12	18	393.924
#447	MEIS1	6	13	19	597.028
#448	PCGF2	6	29	35	925.821
#449	SLC26A3	6	20	26	652.345
#450	ARNT2	6	13	19	367.492
#451	ATF7	6	9	15	458.183
#452	TP63	6	22	28	795.432
#453	ETV6	6	17	23	446.847
#454	ISL1	6	25	31	1107.525
#455	HOXC11	6	12	18	396.504
#456	TCF7L2	6	25	31	1015.582
#457	LHX2	6	19	25	813.643
#458	CDKN2A	5	24	29	586.564
#459	TCF20	5	16	21	935.833
#460	AEBP1	5	18	23	650.498
#461	ZNF232	5	20	25	699.761
#462	POU6F1	5	14	19	335.127
#463	NFIC	5	18	23	508.139
#464	RBCK1	5	15	20	294.719
#465	TAF5L	5	14	19	703.01
#466	FOXN3	5	23	28	610.844
#467	TGIF2	5	18	23	290.994
#468	PEG3	5	16	21	322.368
#469	PBX3	5	18	23	703.165
#470	PURA	5	25	30	1220.058
#471	ELF5	5	18	23	471.574
#472	TBX3	5	17	22	308.794
#473	HOXC10	5	23	28	393.536
#474	GATAD1	5	14	19	442.311
#475	SPEN	5	20	25	486.094
#476	MYT1	4	7	11	320.309
#477	TADA3	4	17	21	327.27
#478	ZNF35	4	14	18	421.557
#479	GCFC1	4	19	23	416.71
#480	TBP	4	20	24	451.984
#481	ZNF174	4	21	25	466.129
#482	BUD31	4	20	24	596.089
#483	CITED1	3	12	15	346.307
#484	NR4A3	3	29	32	426.251
#485	MGA	3	23	26	856.264
#486	TAF5	3	25	28	638.497
#487	HOXA9	3	18	21	462.142
#488	HOPX	3	15	18	321.284
#489	NPAS2	3	13	16	407.884
#490	HEY2	3	20	23	364.789
#491	SCML1	3	17	20	284.405
#492	FOXG1	3	20	23	358.042
#493	ZNF117	3	22	25	338.73
#494	MSRB2	2	17	19	272.392
#495	NR2E3	2	11	13	362.636
#496	TRIM22	2	22	24	987.506
#497	FUBP1	2	24	26	239.129
#498	CNOT8	2	18	20	147.484
#499	MSX2	2	14	16	127.003
#500	ARNTL2	0	19	19	0