Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	BACH1	38	1	39	134.945
#2	GABPB1	37	2	39	51.926
#3	HIF1A	34	8	42	1483.422
#4	ATF3	34	9	43	1211.684
#5	NR4A1	34	7	41	427.639
#6	ENO1	32	6	38	778.753
#7	ZEB1	31	6	37	4018.169
#8	ELK4	30	4	34	1050.165
#9	TSC22D3	30	7	37	524.225
#10	CITED2	29	5	34	534.876
#11	NANOGNB	29	6	35	889.816
#12	NFIL3	28	6	34	599.065
#13	CREM	28	4	32	932.492
#14	ZNF75D	27	11	38	521.172
#15	HSF5	27	10	37	848.499
#16	MZF1	25	12	37	1798.741
#17	NR4A2	25	2	27	26.979
#18	MEF2C	24	7	31	446.988
#19	GLI2	24	9	33	2274.565
#20	STRN3	24	8	32	1248.436
#21	FOXP1	24	13	37	1766.891
#22	IKZF1	24	9	33	298.274
#23	MEF2A	24	7	31	149.423
#24	THRB	23	14	37	1899.845
#25	TFCP2L1	23	12	35	1404.141
#26	TFE3	23	11	34	785.587
#27	IRF5	23	10	33	682.813
#28	NFE2L3	23	15	38	1107.287
#29	LHX3	22	10	32	3033.495
#30	MYC	22	10	32	464.472
#31	LEF1	22	8	30	1994.679
#32	KLF6	22	8	30	3962.677
#33	ZNF397	22	11	33	468.938
#34	EGR2	22	8	30	567.846
#35	ZNF80	21	14	35	2147.674
#36	KLF10	21	10	31	314.01
#37	ZNF287	21	12	33	2806.048
#38	FOXK1	21	16	37	1995.659
#39	KCNH8	21	7	28	548.914
#40	PHTF1	21	10	31	4472.82
#41	SOX30	21	11	32	757.404
#42	LMO4	21	12	33	1386.441
#43	ZNF165	20	5	25	547.965
#44	ZNF207	20	16	36	2476.932
#45	SMAD2	20	11	31	1322.379
#46	EGR3	20	10	30	910.17
#47	PPBPL2	20	14	34	1659.012
#48	SOX7	19	7	26	1569.255
#49	GAS7	19	14	33	2379.11
#50	THRA	19	8	27	415.06
#51	PBX4	19	17	36	1580.203
#52	KLF12	19	8	27	1576.826
#53	MAFB	19	18	37	2405.877
#54	FOSB	19	7	26	431.092
#55	SATB1	19	11	30	1832.013
#56	KLF3	19	10	29	670.261
#57	SIX5	19	8	27	827.091
#58	RFXAP	19	8	27	685.832
#59	SIN3A	19	11	30	1678.708
#60	HOXB7	19	11	30	1486.912
#61	JUNB	19	5	24	116.275
#62	RXRA	19	7	26	275.935
#63	TCF7	19	7	26	1460.841
#64	BHLHE40	19	12	31	2612.728
#65	ATF2	18	9	27	1244.736
#66	MAFF	18	7	25	232.19
#67	PPARD	18	14	32	1739.799
#68	SALL2	18	11	29	1390.071
#69	NFE2L2	18	12	30	3452.035
#70	FOS	18	11	29	565.628
#71	PRDM2	18	11	29	1360.662
#72	JUN	18	6	24	1298.038
#73	EGR4	17	9	26	1206.132
#74	MEIS3P1	17	5	22	5369.797
#75	FUBP1	17	13	30	809.323
#76	TSHZ2	17	11	28	1005.119
#77	MXD1	17	10	27	1085.421
#78	ZNF71	17	10	27	741.963
#79	TBX6	17	11	28	1291.805
#80	SOX10	17	10	27	1474.43
#81	TCF25	17	5	22	132.188
#82	CBL	17	7	24	738.528
#83	L3MBTL4	17	13	30	1920.606
#84	HOXB3	17	13	30	1615.863
#85	STAT2	17	10	27	391.273
#86	PRRX1	16	12	28	2090.492
#87	NR2F6	16	13	29	4369.339
#88	ZFPM2	16	13	29	925.972
#89	SNAI2	16	9	25	903.636
#90	FOXC2	16	13	29	1802.827
#91	NR4A3	16	8	24	1682.829
#92	HIC1	16	13	29	978.159
#93	ATF5	16	9	25	1107.094
#94	ZNF135	16	8	24	2174.451
#95	GATA2	16	12	28	1485.658
#96	NKX6-2	16	13	29	1799.576
#97	TFDP2	16	8	24	620.687
#98	ESRRB	15	12	27	1799.055
#99	BLZF1	15	13	28	766.994
#100	NFIX	15	12	27	946.054
#101	ZNF444	15	4	19	650.904
#102	ZNF3	15	10	25	1427.958
#103	HESX1	15	10	25	622.679
#104	NPAT	15	8	23	713.556
#105	PDX1	15	10	25	808.104
#106	ETV5	15	8	23	536.304
#107	ESR1	15	9	24	1206.604
#108	PTH	15	8	23	976.288
#109	TWIST2	15	8	23	799.095
#110	LASS6	15	14	29	1401.116
#111	RORB	15	13	28	1937.24
#112	GCM1	15	10	25	661.295
#113	HOXC9	15	11	26	987.992
#114	KLF1	15	6	21	555.892
#115	TRIM29	14	12	26	1235.102
#116	FOSL2	14	10	24	766.832
#117	SOX11	14	12	26	1253.683
#118	WNT5A	14	11	25	1160.14
#119	MYBL2	14	12	26	1779.528
#120	RARA	14	12	26	594.797
#121	ZKSCAN3	14	10	24	359.753
#122	MTA2	14	13	27	1473.315
#123	ZSCAN12	14	10	24	936.23
#124	ZIC2	14	12	26	1892.613
#125	PAX8	14	12	26	1220.098
#126	HOXA9	14	13	27	2204.17
#127	CUX2	14	11	25	1010.749
#128	POU3F2	14	10	24	827.483
#129	ZFP37	14	12	26	1944.584
#130	SOX1	14	9	23	1628.804
#131	MEIS1	14	8	22	872.208
#132	ZNF157	14	15	29	1120.204
#133	ZIC3	14	12	26	1287.609
#134	E2F2	14	15	29	1302.468
#135	NPAS1	14	9	23	812.053
#136	NEUROG1	14	11	25	1925.035
#137	RCOR2	14	13	27	3680.549
#138	GATA5	13	13	26	1413.466
#139	NFIB	13	13	26	995.463
#140	TBX15	13	9	22	434.305
#141	ARNT2	13	11	24	1630.533
#142	DMRT2	13	13	26	1251.601
#143	ZNF175	13	8	21	712.817
#144	HES1	13	10	23	965.928
#145	SMAD6	13	13	26	880.091
#146	MSX1	13	13	26	1091.586
#147	NEUROD2	13	11	24	999.041
#148	IRF6	13	9	22	995.617
#149	OVOL1	13	13	26	1228.478
#150	NKX6-1	13	12	25	1345.354
#151	FOXO3	13	11	24	1096.956
#152	IRX3	13	11	24	1857.641
#153	STAT5B	13	11	24	684.589
#154	MSRB2	13	8	21	1225.891
#155	TP63	13	14	27	1186.368
#156	CSRNP3	13	15	28	1442.164
#157	HMG20B	13	9	22	683.075
#158	MYT1	13	11	24	1183.645
#159	JUND	13	17	30	1365.868
#160	CREBBP	13	9	22	785.804
#161	ZNF192	13	10	23	732.506
#162	RORA	13	20	33	1856.273
#163	AEBP1	13	12	25	983.859
#164	MSC	13	8	21	1307.164
#165	FOXP3	13	10	23	1106.383
#166	TWIST1	13	12	25	1423.521
#167	HIF3A	13	13	26	822.447
#168	MMP14	12	12	24	1175.077
#169	SMAD3	12	11	23	1916.745
#170	PEG3	12	8	20	1266.101
#171	HNF1A	12	8	20	798.991
#172	MYF5	12	14	26	1669.479
#173	KLF7	12	8	20	705.577
#174	TFAP2B	12	14	26	1207.504
#175	TULP4	12	9	21	1134.17
#176	ETV1	12	6	18	636.613
#177	USF1	12	9	21	747.602
#178	TAF13	12	8	20	635.124
#179	KLF15	12	15	27	1275.222
#180	EPAS1	12	12	24	756.425
#181	TRERF1	12	9	21	635.64
#182	PBX1	12	13	25	1204.375
#183	TCF7L1	12	8	20	704.059
#184	EGR1	12	7	19	202.005
#185	TSC22D1	12	14	26	1862.89
#186	ZFHX3	12	12	24	807.317
#187	AHR	12	15	27	1280.494
#188	MLXIPL	12	10	22	690.286
#189	REST	12	10	22	688.578
#190	ELK1	12	10	22	1005.731
#191	POU4F2	12	10	22	1245.258
#192	TBX2	12	14	26	860.135
#193	ZFP36L1	12	9	21	666.109
#194	SOX6	12	13	25	1357.672
#195	HOXA10	12	14	26	2239.907
#196	ETV7	12	13	25	1236.109
#197	BHLHE41	12	6	18	444.428
#198	SOX4	12	15	27	1544.927
#199	MLLT10	12	14	26	1320.701
#200	ZNF483	12	13	25	1475.731
#201	SIX1	12	13	25	1230.016
#202	PAX4	12	12	24	1276.815
#203	ZSCAN4	12	11	23	867.13
#204	ARNTL	12	11	23	999.45
#205	ATOH1	12	14	26	1396.184
#206	SEBOX	12	12	24	931.315
#207	ZNF117	12	13	25	808.406
#208	RUNX1T1	12	13	25	1663.386
#209	HOXA3	12	11	23	780.696
#210	TRPS1	12	11	23	1058.082
#211	TBX5	12	11	23	785.694
#212	NFE2	11	12	23	900.805
#213	ETV4	11	8	19	620.353
#214	C12orf28	11	12	23	1154.976
#215	SIM2	11	14	25	915.003
#216	MNX1	11	13	24	1280.861
#217	ELK3	11	11	22	1383.272
#218	PAX6	11	14	25	1184.217
#219	TCF7L2	11	13	24	1082.367
#220	BCL11B	11	12	23	1505.588
#221	ONECUT2	11	12	23	1021.643
#222	HNF4G	11	9	20	927.039
#223	NFIA	11	13	24	1113.285
#224	NR2F1	11	13	24	1098.701
#225	SOX2	11	9	20	990.488
#226	VDR	11	15	26	1274.122
#227	IRF4	11	11	22	990.584
#228	HOXA2	11	8	19	641.232
#229	TEAD3	11	9	20	618.166
#230	FOXL1	11	17	28	1621.198
#231	POU4F1	11	15	26	1130.424
#232	MECOM	11	12	23	1352.295
#233	TBX3	11	6	17	583.12
#234	HOXD3	11	11	22	685.5
#235	TBX22	11	10	21	759.759
#236	ARNTL2	11	12	23	893.463
#237	POU3F3	11	12	23	1095.643
#238	SP1	11	13	24	570.665
#239	ISL2	11	11	22	736.213
#240	ST18	11	11	22	1143.408
#241	EN2	11	8	19	1034.176
#242	BRD8	11	11	22	1118.921
#243	FOSL1	11	9	20	624.942
#244	DLX4	11	14	25	1506.905
#245	ANKRD30A	11	11	22	622.014
#246	KLF5	11	8	19	489.633
#247	HOXB9	11	11	22	1266.054
#248	FOXC1	11	11	22	3348.058
#249	POU5F2	11	13	24	1215.16
#250	NR0B1	11	15	26	1676.778
#251	HMGA2	11	17	28	1554.38
#252	TCF20	11	9	20	620.412
#253	CTBP1	11	16	27	1286.642
#254	POU1F1	11	19	30	1912.324
#255	STAT4	11	11	22	994.056
#256	PAX5	11	9	20	720.26
#257	TAL1	11	14	25	1052.919
#258	SOX8	11	10	21	843.215
#259	NR5A2	11	10	21	1440.218
#260	GLIS3	11	13	24	1300.945
#261	BATF2	11	17	28	857.892
#262	HOXC5	11	11	22	1245.487
#263	GATAD1	11	13	24	1364.412
#264	PKNOX2	11	12	23	1064.148
#265	ESRRG	11	15	26	2707.781
#266	HOXA4	10	13	23	908.653
#267	MEOX2	10	11	21	698.736
#268	NR2F2	10	16	26	1106.58
#269	LASS5	10	14	24	839.65
#270	FOXD3	10	12	22	969.465
#271	SOX21	10	15	25	1321.283
#272	HOXC10	10	8	18	655.591
#273	HOXB8	10	14	24	1573.188
#274	PPARA	10	13	23	1014.652
#275	DLX1	10	10	20	679.709
#276	SIM1	10	15	25	1036.282
#277	PGR	10	10	20	1193.455
#278	FOXP2	10	13	23	939.703
#279	HOXC4	10	19	29	727.779
#280	BARX1	10	13	23	1109.828
#281	GSC2	10	15	25	1153.773
#282	HNF4A	10	13	23	890.113
#283	RUNX3	10	17	27	1269.111
#284	E2F7	10	12	22	1008.534
#285	ETS2	10	12	22	1363.598
#286	MESP1	10	6	16	358.159
#287	GATA6	10	16	26	1115.883
#288	HOXD10	10	15	25	976.079
#289	MAF	10	11	21	974.937
#290	GATAD2A	10	13	23	1157.967
#291	NOTCH1	10	15	25	1163.642
#292	ZNF90	10	14	24	701.278
#293	FOXF1	10	10	20	1383.386
#294	MLL	10	9	19	660.248
#295	POU3F4	10	11	21	849.24
#296	NR6A1	10	11	21	874.415
#297	ZNF85	10	9	19	834.508
#298	ELF3	10	10	20	937.241
#299	GATA4	10	15	25	1496.876
#300	HOXC12	10	8	18	581.78
#301	ZNF396	10	17	27	746.749
#302	EN1	10	13	23	1359.981
#303	HEY2	10	10	20	983.116
#304	TCF3	10	12	22	947.907
#305	ZNF93	10	14	24	959.135
#306	POU4F3	10	9	19	717.896
#307	RBPJL	10	11	21	959.135
#308	UHRF1	10	13	23	1311.57
#309	SCML1	10	16	26	464.182
#310	HOXD13	10	13	23	888.028
#311	NEUROD1	10	14	24	1248.498
#312	MYCN	9	11	20	870.653
#313	RXRG	9	14	23	1058.536
#314	PLSCR1	9	13	22	1089.054
#315	NANOG	9	14	23	799.664
#316	ARX	9	8	17	693.509
#317	LHX9	9	16	25	1305.005
#318	MYF6	9	20	29	1032.686
#319	KLF4	9	14	23	551.317
#320	GSX1	9	16	25	1107.321
#321	CREB3L3	9	12	21	648.667
#322	RCOR1	9	13	22	869.34
#323	PITX2	9	16	25	1012.56
#324	PAX7	9	19	28	1054.125
#325	AR	9	13	22	990.617
#326	NR3C2	9	14	23	937.158
#327	RARG	9	12	21	1024.907
#328	ZNF81	9	13	22	1078.81
#329	C11orf9	9	13	22	880.73
#330	NCOR1	9	20	29	1540.437
#331	HOXD1	9	15	24	1003.845
#332	PRDM1	9	14	23	1369.839
#333	SIX2	9	7	16	606.538
#334	HMX2	9	13	22	966.411
#335	NFATC2	9	10	19	624.82
#336	FOXD4	9	14	23	802.817
#337	GATA3	9	12	21	755.836
#338	SOX13	9	12	21	981.261
#339	SPIC	9	17	26	1531.866
#340	HOXD4	9	14	23	711.235
#341	NKX2-3	9	11	20	1110.634
#342	SLC26A3	9	11	20	586.161
#343	GLIS2	9	15	24	1112.053
#344	ZHX3	9	9	18	563.81
#345	POU2F1	9	12	21	660.136
#346	CREB3L1	9	9	18	958.947
#347	ERG	9	10	19	713.919
#348	EBF1	9	8	17	470.663
#349	AFF4	9	14	23	948.538
#350	FOXE1	9	12	21	990.021
#351	HES6	9	16	25	1035.381
#352	MSX2	9	10	19	753.36
#353	MYT1L	9	17	26	1031.813
#354	ONECUT1	9	15	24	1700.942
#355	ZSCAN20	9	15	24	768.218
#356	FLI1	9	10	19	757.446
#357	NR2E3	9	14	23	910.186
#358	MITF	9	15	24	991.901
#359	PHOX2B	9	14	23	848.281
#360	TEAD2	8	15	23	1530.521
#361	BNC1	8	12	20	1057.458
#362	TFEC	8	18	26	1076.932
#363	IRX1	8	8	16	399.816
#364	NFYA	8	15	23	1042.312
#365	FOXR2	8	9	17	771.51
#366	NKX3-2	8	12	20	739.637
#367	MYNN	8	11	19	659.359
#368	C2orf3	8	12	20	708.457
#369	ZFP42	8	14	22	868.266
#370	TADA3	8	10	18	446.315
#371	SOX9	8	8	16	682.525
#372	SIX4	8	11	19	936.018
#373	NR1I3	8	13	21	878.262
#374	ZNF19	8	13	21	1378.119
#375	SMAD4	8	12	20	1009.189
#376	ZSCAN2	8	14	22	597.688
#377	HMGB2	8	15	23	694.962
#378	FOXB1	8	12	20	921.569
#379	TLX2	8	12	20	662.584
#380	TADA2A	8	15	23	829.398
#381	ISL1	8	13	21	860.708
#382	SALL1	8	14	22	943.62
#383	ZNF132	8	16	24	242.548
#384	TFAP2C	8	14	22	955.498
#385	KLF11	8	9	17	194.667
#386	OTX1	8	15	23	880.242
#387	ZSCAN23	8	16	24	1436.78
#388	DLX3	8	10	18	606.244
#389	FOXF2	8	12	20	951.063
#390	ATF7	8	11	19	561.354
#391	SATB2	8	14	22	845.896
#392	ZIC1	8	10	18	602.367
#393	MYCL1	8	11	19	703.42
#394	MGA	8	12	20	851.021
#395	HNRNPAB	8	17	25	675.748
#396	LHX8	8	18	26	1031.537
#397	NFATC4	8	12	20	706.238
#398	ZNF215	8	18	26	939.966
#399	HDX	8	10	18	1244.98
#400	ETV2	8	13	21	698.782
#401	CEBPA	8	9	17	851.937
#402	DLX6	8	15	23	991.307
#403	NR1I2	8	12	20	604.312
#404	EHF	8	18	26	1195.487
#405	ESX1	7	11	18	491.018
#406	OTX2	7	13	20	841.358
#407	MKX	7	16	23	1323.188
#408	ELF5	7	10	17	751.12
#409	NR5A1	7	12	19	628.389
#410	HOXB6	7	14	21	840.878
#411	HIRA	7	13	20	983.808
#412	ZFHX2	7	11	18	462.631
#413	FOXS1	7	13	20	1368.206
#414	HOXA5	7	16	23	649.828
#415	LMX1A	7	12	19	682.566
#416	GSX2	7	9	16	872.034
#417	TEAD1	7	16	23	1041.006
#418	FOXN4	7	16	23	749.7
#419	LHX6	7	12	19	618.547
#420	FOXD1	7	12	19	459.983
#421	PROX1	7	19	26	1081.545
#422	SOX5	7	11	18	365.884
#423	DLX2	7	11	18	902.884
#424	FOXA3	7	14	21	741.605
#425	RCAN1	7	14	21	631.541
#426	PAX3	7	13	20	657.383
#427	NFATC1	7	11	18	819.635
#428	ZEB2	7	14	21	675.257
#429	HLF	7	15	22	853.011
#430	RUNX2	7	17	24	892.757
#431	DMBX1	7	11	18	749.026
#432	TBX20	7	12	19	495.867
#433	NFKB2	7	7	14	816.185
#434	CREB5	7	15	22	733.214
#435	VTN	7	14	21	971.989
#436	HOPX	7	9	16	605.995
#437	TLX3	6	8	14	513.988
#438	RUNX1	6	16	22	544.628
#439	HOXD11	6	12	18	550.137
#440	HOXA1	6	14	20	786.818
#441	NR1H4	6	12	18	654.922
#442	VSX1	6	15	21	817.44
#443	FOXL2	6	11	17	587.978
#444	KLF9	6	14	20	491.398
#445	RERE	6	12	18	518.312
#446	SOX17	6	8	14	528.057
#447	ISX	6	18	24	1052.599
#448	FOXM1	6	16	22	755.012
#449	SMAD1	6	11	17	502.526
#450	PPARG	6	11	17	531.155
#451	ESR2	6	13	19	793.085
#452	NPAS2	6	11	17	411.128
#453	TBX1	6	12	18	652.634
#454	ZFHX4	6	15	21	727.854
#455	TFDP3	6	13	19	963.338
#456	SCRT1	6	18	24	959.201
#457	TGIF2LY	6	13	19	1282.686
#458	FOXA1	6	14	20	674.943
#459	RARB	6	16	22	744.972
#460	ARNT	6	17	23	812.801
#461	FOXI1	6	17	23	723.298
#462	FOXH1	6	13	19	602.645
#463	ASCL1	6	11	17	469.44
#464	TBR1	5	15	20	845.197
#465	KLF17	5	14	19	579.682
#466	POU2F3	5	16	21	609.696
#467	TCF21	5	15	20	499.666
#468	CEBPD	5	12	17	537.271
#469	ZSCAN10	5	14	19	390.357
#470	SLC2A4RG	5	14	19	788.036
#471	PBX3	5	12	17	569.606
#472	NKX3-1	5	10	15	453.519
#473	E2F8	5	13	18	553.275
#474	CREBZF	5	12	17	438.334
#475	ZSCAN1	5	9	14	258.268
#476	ZNF131	4	13	17	348.761
#477	LZTS1	4	17	21	548.968
#478	TSC22D2	4	17	21	503.155
#479	GTF2IRD1	4	14	18	624.071
#480	FOXA2	4	13	17	535.771
#481	LHX2	4	16	20	665.529
#482	IRX5	4	7	11	195.938
#483	IRX4	4	9	13	319.059
#484	FOXD2	4	13	17	585.429
#485	TEF	4	13	17	465.584
#486	MIXL1	4	14	18	515.445
#487	ASCL2	4	15	19	469.831
#488	HOXA6	4	13	17	467.179
#489	TP73	4	14	18	625.302
#490	CCRN4L	4	10	14	937.459
#491	SOX18	4	14	18	444.42
#492	HOXB2	4	16	20	679.669
#493	SIX3	4	17	21	385.058
#494	NKX2-8	4	17	21	414.728
#495	TSHZ3	3	17	20	690.155
#496	NKX2-1	3	18	21	513.473
#497	KLF2	3	17	20	375.831
#498	OLIG2	3	13	16	406.373
#499	DMRT1	2	15	17	269.772
#500	SCAND3	1	16	17	197.44