Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	YBX1	64	3	67	424.758
#2	ENO1	63	2	65	3061.958
#3	NFIC	51	6	57	996.425
#4	CNOT8	50	2	52	762.855
#5	UBN1	49	2	51	47.919
#6	MLXIPL	47	5	52	1421.579
#7	NFAT5	47	8	55	848.237
#8	HNF4A	46	4	50	1046.836
#9	ELF1	42	5	47	1616.831
#10	AR	41	8	49	2009.615
#11	E2F3	41	9	50	1382.277
#12	ZFHX3	40	11	51	925.566
#13	ZNF148	39	3	42	260.121
#14	HCLS1	38	1	39	24.921
#15	TCF25	37	4	41	128.555
#16	GTF2H3	37	3	40	1181.856
#17	HLF	37	10	47	3431.509
#18	CREBL2	37	7	44	491.849
#19	SP1	37	4	41	105.195
#20	CREB1	36	2	38	17.853
#21	ZEB2	36	6	42	315.514
#22	ZXDC	35	10	45	4767.208
#23	KLF9	34	9	43	1098.235
#24	HOXA2	34	14	48	8396.627
#25	TSC22D1	34	10	44	1261.454
#26	MLL	34	5	39	3482.655
#27	RXRA	34	8	42	3736.713
#28	YEATS4	33	7	40	428.454
#29	CSDA	33	9	42	1593.744
#30	KLF15	33	4	37	180.211
#31	NR2F6	32	8	40	3817.07
#32	HIF1A	32	8	40	1605.473
#33	SMAD4	31	11	42	425.924
#34	RBPJ	31	11	42	2190.636
#35	IKZF1	30	1	31	517.526
#36	TEAD4	30	15	45	3563.476
#37	RELA	30	5	35	155.576
#38	TBX3	30	9	39	3068.367
#39	NFE2L3	30	14	44	2263.997
#40	FOXM1	29	4	33	1150.461
#41	ARID3A	29	8	37	1142.568
#42	TULP4	29	6	35	1046.541
#43	RUNX2	29	10	39	3223.388
#44	MITF	29	8	37	2591.555
#45	FOXF1	28	7	35	3217.562
#46	RFX1	28	6	34	1156.891
#47	MZF1	28	8	36	480.314
#48	NR2F2	28	7	35	183.868
#49	TCEAL1	28	13	41	2782.467
#50	HDAC2	27	10	37	900.358
#51	NFE2L2	27	8	35	477.628
#52	SPEN	27	6	33	97.441
#53	TEAD2	27	9	36	1108.145
#54	GABPA	27	10	37	329.529
#55	STAT1	27	14	41	1977.451
#56	ADNP	27	8	35	273.179
#57	RUNX3	27	3	30	1465.387
#58	CBFA2T2	27	11	38	740.211
#59	MEF2C	26	8	34	1579.022
#60	NFIB	26	11	37	351.269
#61	VTN	26	16	42	11688.596
#62	SALL1	26	12	38	3977.435
#63	KDM5A	25	8	33	476.102
#64	NOLC1	25	5	30	344.884
#65	NFXL1	25	5	30	948.33
#66	MGA	25	3	28	21.006
#67	ELF4	25	9	34	4698.855
#68	TFDP2	25	14	39	2337.959
#69	NFIA	24	10	34	1145.988
#70	MLLT10	24	10	34	1436.303
#71	MEIS3P1	24	12	36	1547.309
#72	FLI1	24	4	28	2040.505
#73	KLF3	24	8	32	1452.461
#74	TCF7	24	11	35	1340.998
#75	TFEC	24	6	30	288.117
#76	E2F7	23	5	28	173.522
#77	MYBL2	23	12	35	4271.656
#78	HHEX	23	11	34	613.542
#79	NR1H4	23	15	38	982.081
#80	TCF4	23	11	34	6129.347
#81	NFIX	23	10	33	3374.814
#82	RORC	23	8	31	2089.219
#83	ATF1	23	10	33	371.611
#84	TFAM	23	11	34	1614.584
#85	GLIS2	22	16	38	2244.712
#86	SOX4	22	13	35	1198.66
#87	PROX1	22	14	36	3904.919
#88	PTTG1	22	9	31	601.775
#89	ELK3	22	9	31	4591.429
#90	JUNB	22	9	31	311.518
#91	HDAC1	22	10	32	759.474
#92	CSRNP2	22	13	35	1195.093
#93	GATA3	22	8	30	638.147
#94	PRDM1	21	8	29	1184.671
#95	BRD8	21	12	33	15476.316
#96	ONECUT2	21	17	38	2135.958
#97	NR3C1	21	8	29	320.558
#98	MLX	21	12	33	989.73
#99	AEBP1	21	4	25	317.337
#100	ATF2	21	13	34	1550.691
#101	MYCL1	21	13	34	1353.231
#102	EGR2	20	13	33	1173.329
#103	ERG	20	6	26	784.795
#104	ONECUT1	20	13	33	1430.324
#105	TRERF1	20	5	25	310.975
#106	HSF2	20	9	29	1964.082
#107	SOX13	20	11	31	745.355
#108	ZEB1	20	7	27	411.762
#109	ZKSCAN1	20	8	28	404.321
#110	NR1I2	20	14	34	783.667
#111	TSHZ2	20	20	40	2684.531
#112	CITED2	20	13	33	253.599
#113	RORA	20	22	42	5183.655
#114	SP3	20	13	33	2225.938
#115	ZFP36L2	20	9	29	1239.986
#116	ZFPM1	20	11	31	2393.672
#117	NR5A2	19	11	30	608.657
#118	LCOR	19	15	34	1237.418
#119	RXRB	19	9	28	3093.123
#120	RUNX1	19	10	29	3799.157
#121	CNOT7	19	10	29	567.988
#122	ZFPM2	19	5	24	351.724
#123	SATB1	19	22	41	18522.984
#124	MAX	19	10	29	904.22
#125	FUBP1	19	11	30	850.619
#126	TAF12	19	8	27	124.468
#127	E2F5	19	18	37	1626.589
#128	PCGF6	18	11	29	381.55
#129	NFYC	18	7	25	1082.871
#130	TCF12	18	6	24	5874.339
#131	PA2G4	18	8	26	304.385
#132	E2F8	18	12	30	455.08
#133	SMAD1	18	13	31	1715.028
#134	EGR3	18	10	28	378.996
#135	TSC22D4	18	10	28	2540.681
#136	RCAN1	18	18	36	2266.105
#137	TFDP1	18	12	30	686.061
#138	TRIM28	17	10	27	1757.684
#139	MESP1	17	14	31	8748.763
#140	ZNF277	17	11	28	873.55
#141	PBX1	17	17	34	4110.225
#142	HSF1	17	8	25	4984.811
#143	FOXP1	17	13	30	565.969
#144	MTA1	17	12	29	970.614
#145	CSRNP1	17	8	25	571.751
#146	UHRF1	16	14	30	1762.911
#147	PURA	16	13	29	1959.541
#148	SOX15	16	11	27	395.62
#149	MECOM	16	11	27	5794.426
#150	TFEB	16	16	32	1257.35
#151	HOXB3	16	9	25	923.662
#152	TCF7L2	16	13	29	1011.12
#153	CBFB	16	17	33	1092.205
#154	AFF1	16	8	24	5155.449
#155	FOS	16	7	23	123.641
#156	PRRX1	16	14	30	1122.393
#157	HMGB2	16	11	27	721.577
#158	BLZF1	16	13	29	450.205
#159	HOXD10	16	15	31	2435.303
#160	FOXP4	16	16	32	863.187
#161	FOXN2	16	13	29	766.741
#162	C5orf41	16	14	30	1459.159
#163	RB1	16	11	27	612.687
#164	AFF4	16	14	30	1640.564
#165	ARNT	16	9	25	68.316
#166	ETV5	16	16	32	4063.662
#167	ZNF70	15	13	28	1114.056
#168	SIN3A	15	14	29	1017.136
#169	IRX5	15	7	22	2348.359
#170	PPARD	15	12	27	1015.641
#171	RERE	15	12	27	1138.752
#172	SOLH	15	9	24	2401.983
#173	BCL11B	15	5	20	93.656
#174	SLC2A4RG	15	13	28	439.478
#175	TSC22D2	15	14	29	530.936
#176	HNF4G	15	15	30	1866.182
#177	FOXO1	15	15	30	1526.305
#178	ZNF207	14	14	28	18704.66
#179	ZNF238	14	13	27	4518.552
#180	PHF1	14	19	33	540.446
#181	ZSCAN21	14	15	29	1743.684
#182	VAV1	14	6	20	586.688
#183	JUND	14	13	27	2072.033
#184	SNAI2	14	29	43	3588.295
#185	NR1I3	14	17	31	759.174
#186	KLF2	14	10	24	799.877
#187	RUNX1T1	14	10	24	358.915
#188	SUPT4H1	14	10	24	385.046
#189	GLIS3	14	12	26	982.438
#190	HEY1	14	13	27	1936.919
#191	REL	14	13	27	1497.301
#192	ATF4	14	11	25	1136.352
#193	E2F6	14	13	27	2732.931
#194	RFXAP	13	13	26	518.989
#195	ZFHX4	13	14	27	1828.814
#196	NR1H2	13	13	26	1131.563
#197	RCOR1	13	11	24	695.818
#198	HEYL	13	10	23	468.08
#199	LASS6	13	16	29	3203.144
#200	TP53	13	14	27	660.714
#201	CTNNB1	13	14	27	586.974
#202	CEBPB	13	18	31	2087.369
#203	KDM5B	13	19	32	1071.691
#204	GATAD2B	13	10	23	280.566
#205	HOPX	13	9	22	949.103
#206	ZNF496	13	16	29	965.675
#207	GATAD1	13	18	31	1412.512
#208	SMAD3	13	12	25	1270.82
#209	HMGA1	13	13	26	1070.229
#210	CREB3L2	13	13	26	2833.497
#211	NR4A1	13	12	25	706.457
#212	ARNTL2	13	15	28	1288.177
#213	EGR1	13	13	26	1128.027
#214	SOX9	13	19	32	1146.103
#215	IRF6	13	23	36	2172.407
#216	GAS7	13	13	26	3261.406
#217	FOXA2	13	15	28	1125.991
#218	MEIS2	12	18	30	3489.547
#219	HOXA3	12	20	32	4397.289
#220	NFX1	12	13	25	2228.637
#221	SMAD2	12	12	24	1201.58
#222	FOXA3	12	15	27	1389.259
#223	TEF	12	18	30	1335.712
#224	BACH1	12	9	21	1568.428
#225	NANOGNB	12	13	25	167.99
#226	GTF2I	12	11	23	655.69
#227	EPAS1	12	13	25	1099.674
#228	KLF6	12	15	27	2016.603
#229	BTG2	12	19	31	671.554
#230	LZTS1	12	12	24	1714.099
#231	TFE3	12	10	22	207.861
#232	BHLHE41	12	17	29	6791.609
#233	NFE2L1	12	19	31	891.819
#234	RARA	12	14	26	803.927
#235	PBX3	12	13	25	1302.221
#236	CREBZF	12	12	24	435.945
#237	STAT6	12	15	27	626.97
#238	ZNF45	12	11	23	345.869
#239	CBL	12	8	20	256.136
#240	ZNF202	12	14	26	1223.584
#241	HOXD8	12	12	24	1110.726
#242	SP140	12	9	21	2095.797
#243	ETS2	12	16	28	3828.205
#244	KLF12	12	15	27	1257.683
#245	HMGA2	12	18	30	3781.095
#246	TAF5	11	17	28	1567.725
#247	ETS1	11	19	30	626.973
#248	ZRANB2	11	8	19	123.436
#249	ZNF281	11	18	29	2711.881
#250	ZNF91	11	18	29	1349.214
#251	TAL1	11	8	19	1004.048
#252	ARID4A	11	11	22	257.533
#253	CEBPA	11	20	31	1661.621
#254	ZNF189	11	17	28	1157.262
#255	FOXN3	11	13	24	3892.558
#256	AHR	11	22	33	1764.817
#257	PCGF2	11	12	23	994.953
#258	LHX2	11	12	23	3880.426
#259	HOXB7	11	18	29	1275.4
#260	TWIST2	11	10	21	1156.08
#261	ZNF3	11	14	25	1778.72
#262	FBXW7	11	14	25	1288.655
#263	ZNF131	11	14	25	687.447
#264	ZNF628	11	14	25	766.809
#265	ALS2CR8	11	15	26	939.402
#266	ELK4	10	12	22	1086.621
#267	GABPB1	10	18	28	705.807
#268	TCF3	10	15	25	909.263
#269	KLF10	10	18	28	1762.469
#270	NANOG	10	13	23	2331.956
#271	C11orf9	10	12	22	523.802
#272	FOXK2	10	17	27	739.287
#273	TRIM22	10	15	25	1246.336
#274	ESRRG	10	11	21	749.594
#275	TRPS1	10	17	27	1603.228
#276	TAF6	10	17	27	1509.885
#277	NR2F1	10	20	30	4608.805
#278	ZSCAN2	10	12	22	2108.27
#279	WT1	10	13	23	4176.569
#280	LEF1	10	23	33	2611.719
#281	NR4A3	10	13	23	1215.588
#282	STAT4	10	12	22	3147.433
#283	HNF1B	10	13	23	1066.661
#284	CDKN2A	10	17	27	1179.46
#285	TAF4B	10	13	23	273.378
#286	CUX1	10	14	24	972.405
#287	ZNF92	10	12	22	833.201
#288	MYCN	10	16	26	458.187
#289	ZNF140	10	14	24	574.647
#290	PHTF1	10	12	22	1418.254
#291	PITX1	10	15	25	675.563
#292	FOXP3	9	17	26	6432.927
#293	TCF7L1	9	21	30	1778.911
#294	XBP1	9	15	24	309.555
#295	SMAD6	9	10	19	501.87
#296	TCFL5	9	20	29	1282.879
#297	CUX2	9	21	30	2207.111
#298	MAFK	9	22	31	919.532
#299	DLX1	9	14	23	1267.793
#300	CREB3L1	9	12	21	404.599
#301	RARB	9	17	26	1679.139
#302	C2orf3	9	8	17	1106.852
#303	EOMES	9	7	16	31.42
#304	ADNP2	9	6	15	43.569
#305	ZBTB38	9	15	24	1051.416
#306	ZNF232	9	19	28	3712.911
#307	FOSB	9	16	25	1153.362
#308	ATF7	9	10	19	801.4
#309	MEF2A	9	15	24	531.503
#310	PPARA	9	12	21	2140.334
#311	TSHZ1	9	20	29	481.155
#312	PGBD1	9	15	24	1697.128
#313	NFATC2	9	21	30	1825.04
#314	NFYA	9	17	26	860.291
#315	LASS2	9	15	24	1419.043
#316	SP4	8	14	22	1048.595
#317	EHF	8	21	29	1594.405
#318	ZNF83	8	22	30	4744.528
#319	CEBPD	8	21	29	692.549
#320	GATA6	8	22	30	2400.72
#321	CREB3L3	8	17	25	880.807
#322	ZSCAN18	8	16	24	2838.63
#323	KLF5	8	20	28	782.468
#324	ZHX2	8	17	25	391.92
#325	CREM	8	21	29	959.189
#326	DBP	8	17	25	862.348
#327	SATB2	8	19	27	995.283
#328	BCL3	8	19	27	822.32
#329	C1orf85	8	13	21	1794.31
#330	ZNF367	8	15	23	826.252
#331	NR3C2	8	20	28	1637.282
#332	MSC	8	12	20	654.344
#333	NFYB	8	19	27	438.135
#334	STAT2	8	13	21	212.32
#335	PPARG	8	14	22	630.849
#336	JDP2	8	18	26	1763.609
#337	BATF2	8	9	17	914.763
#338	L3MBTL4	8	19	27	1389.075
#339	SALL2	8	20	28	635.674
#340	HOXD1	8	11	19	974.965
#341	STAT3	8	22	30	1112.535
#342	TRIM25	8	16	24	366.224
#343	ZSCAN16	8	11	19	573.17
#344	LMO4	8	21	29	1806.881
#345	TGIF2	8	18	26	658.544
#346	MMP14	8	12	20	407.929
#347	IRF2	8	15	23	1651.637
#348	HOXA1	8	7	15	1486.089
#349	TEAD3	8	15	23	1695.554
#350	ZC3H8	8	15	23	3062.103
#351	HMBOX1	7	19	26	752.207
#352	THRB	7	17	24	769.493
#353	HOXA5	7	18	25	2308.448
#354	SOX18	7	22	29	749.09
#355	DLX2	7	11	18	1619.791
#356	PLSCR1	7	13	20	440.2
#357	TAF7	7	11	18	158.272
#358	PITX2	7	9	16	302.61
#359	STAT5B	7	11	18	270.075
#360	KLF7	7	19	26	745.532
#361	SMAD5	7	18	25	259.017
#362	TCF19	7	8	15	422.314
#363	ZNF323	7	21	28	1647.181
#364	HES1	7	17	24	1314.058
#365	MAFG	7	14	21	2242.341
#366	YY1	7	16	23	1024.992
#367	RXRG	7	20	27	1830.172
#368	MEIS1	7	18	25	1755.535
#369	ETV4	7	20	27	1132.423
#370	SMAD9	7	15	22	605.224
#371	SOX7	7	18	25	796.084
#372	GATAD2A	7	15	22	896.752
#373	ESR1	7	17	24	738.764
#374	TP63	7	16	23	1404.087
#375	TBX15	7	16	23	616.199
#376	TAF5L	7	15	22	1005.302
#377	SOX12	7	18	25	455.537
#378	HIC1	7	12	19	782.27
#379	ZNF37A	7	16	23	1097.046
#380	TLX1	7	10	17	1679.223
#381	PAX6	6	16	22	4051.578
#382	HOXC10	6	11	17	1033.43
#383	IRF8	6	13	19	632.846
#384	ISL1	6	8	14	1614.586
#385	ZNF138	6	13	19	650.671
#386	ELF3	6	20	26	906.71
#387	NKX2-1	6	8	14	643.187
#388	ZNF217	6	18	24	1310.789
#389	BATF	6	19	25	836.081
#390	GTF2H2	6	15	21	133.451
#391	BACH2	6	19	25	2606.946
#392	PLAG1	6	22	28	2653.839
#393	ZFP36L1	6	12	18	375.748
#394	SIX5	6	15	21	470.04
#395	MAFB	6	18	24	637.281
#396	NPAS2	6	20	26	775.19
#397	WNT5A	6	26	32	2610.149
#398	ETV6	6	18	24	1542.255
#399	MEOX2	6	18	24	1638.56
#400	TFCP2	6	19	25	542.399
#401	GTF2IRD1	6	21	27	2019.477
#402	ATF3	6	15	21	498.561
#403	NFATC1	6	10	16	111.534
#404	SLC26A3	6	18	24	925.719
#405	MAFF	6	17	23	1114.231
#406	LHX3	6	11	17	1472.379
#407	CSRNP3	6	22	28	3391.57
#408	ZNF117	5	25	30	737.378
#409	SOX5	5	19	24	580.887
#410	TBX2	5	17	22	414.75
#411	KLF11	5	23	28	933.324
#412	PURB	5	16	21	569.78
#413	NFATC3	5	14	19	134.776
#414	MXD1	5	22	27	1327.877
#415	ZNF75D	5	16	21	661.16
#416	KCNH8	5	15	20	836.036
#417	FOXO3	5	16	21	630.363
#418	HOXD4	5	13	18	692.346
#419	NFIL3	5	18	23	640.12
#420	MSX1	5	18	23	512.357
#421	BCL6	5	22	27	1006.612
#422	ISX	5	20	25	1157.71
#423	ZNF165	5	23	28	555.889
#424	IRF1	5	10	15	250.087
#425	JUN	5	13	18	1231.711
#426	MAF	5	17	22	276.283
#427	ETV7	5	10	15	277.21
#428	HMGB1	5	17	22	839.989
#429	TEAD1	5	12	17	1044.903
#430	EBF1	5	15	20	1049.559
#431	PEG3	5	22	27	2474.436
#432	TFDP3	5	13	18	1214.462
#433	MYC	5	19	24	779.566
#434	ARX	5	7	12	1065.53
#435	TFAP2A	5	22	27	1575.606
#436	NR1H3	4	18	22	1054.43
#437	TGIF1	4	19	23	211.525
#438	ZHX1	4	16	20	1470.828
#439	CTBP1	4	10	14	209.923
#440	FOXC1	4	22	26	1622.177
#441	SREBF1	4	17	21	735.498
#442	DDIT3	4	10	14	302.799
#443	GATA4	4	15	19	927.614
#444	IRF7	4	16	20	3352.672
#445	CLOCK	4	12	16	402.915
#446	FOXP2	4	16	20	299.605
#447	RFX5	4	17	21	413.735
#448	NFKB2	4	18	22	293.316
#449	BHLHE40	4	20	24	598.996
#450	NR4A2	4	18	22	460.615
#451	IRX3	4	24	28	1298.182
#452	SOX2	4	19	23	355.193
#453	HEY2	4	21	25	1645.772
#454	ZNF268	4	21	25	791.336
#455	KLF4	4	14	18	485.959
#456	ZNF256	4	17	21	281.707
#457	NR1D2	4	16	20	900.729
#458	SIM1	4	19	23	1351.653
#459	SCML1	4	18	22	215.393
#460	ZNF33B	4	16	20	729.356
#461	SREBF2	3	16	19	258.505
#462	ZNF24	3	15	18	126.796
#463	CREB5	3	21	24	506.122
#464	ZGPAT	3	21	24	529.159
#465	SLC30A9	3	18	21	2650.273
#466	TSC22D3	3	19	22	212.601
#467	CCRN4L	3	19	22	957.089
#468	ARNT2	3	25	28	252.654
#469	FOSL2	3	24	27	461.791
#470	NCOR1	3	12	15	573.736
#471	ZFP90	3	22	25	214.409
#472	ZIC2	3	24	27	390.704
#473	STRN3	3	20	23	361.959
#474	MKX	3	19	22	254.051
#475	VDR	3	14	17	338.402
#476	SIX1	3	19	22	508.807
#477	SIX4	2	15	17	73.215
#478	FOXQ1	2	26	28	929.01
#479	SCAND3	2	25	27	274.119
#480	HOXA13	2	18	20	253.557
#481	SOX6	2	21	23	1031.994
#482	ZNF167	2	20	22	323.037
#483	ASCL1	2	17	19	501.115
#484	IRF9	2	17	19	480.137
#485	ETV1	2	21	23	373.015
#486	MBD1	2	13	15	135.791
#487	MSRB2	2	17	19	146.277
#488	IRF5	2	20	22	260.874
#489	MSX2	2	4	6	64.731
#490	PGR	2	9	11	188.398
#491	ZIC1	1	24	25	199.452
#492	ARNTL	1	20	21	77.356
#493	ZHX3	1	17	18	403.34
#494	ATF5	1	21	22	122.375
#495	NKX3-1	1	21	22	69.307
#496	HOXA10	1	16	17	620.873
#497	FOXA1	0	16	16	0
#498	AHCTF1	0	25	25	0
#499	LHX9	0	17	17	0
#500	ATF6	0	18	18	0