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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MEIS1	55	0	55	0
#2	ATF1	48	1	49	708.477
#3	ATF2	48	1	49	34.356
#4	MEIS2	43	3	46	32998.396
#5	TCF7L1	43	4	47	1328.061
#6	TAF7	43	6	49	1279.704
#7	TFAM	42	4	46	2647.413
#8	MLL	39	4	43	738.486
#9	HMX1	37	1	38	1215.489
#10	FOXA1	37	5	42	357.591
#11	SPDEF	36	7	43	704.407
#12	FOXN3	36	6	42	900.742
#13	RB1	35	7	42	779.113
#14	FOXO3	35	4	39	3743.61
#15	POU5F1B	34	7	41	2539.539
#16	RBPJ	34	4	38	4702.179
#17	ZEB2	32	5	37	4412.853
#18	TCF12	32	4	36	2740.186
#19	FOXF1	32	5	37	2387.438
#20	MEF2A	32	3	35	907.886
#21	RCOR1	31	5	36	3890.78
#22	RAX	31	5	36	1131.514
#23	E2F4	31	4	35	624.241
#24	SMAD2	31	9	40	1127.963
#25	CREB3L2	30	5	35	1853.53
#26	FOXJ3	30	6	36	2134.345
#27	SP3	30	6	36	572.372
#28	TFAP4	30	3	33	179.737
#29	TEAD3	30	10	40	1308.944
#30	ZNF140	30	5	35	472.526
#31	THRA	29	10	39	1416.885
#32	MYNN	29	6	35	175.764
#33	PPARD	28	4	32	214.837
#34	HMG20A	28	7	35	6461.561
#35	TARDBP	28	6	34	2137.319
#36	NR3C1	28	13	41	4714.311
#37	ELK3	28	8	36	521.943
#38	TRIM28	27	7	34	3936.593
#39	TFE3	27	15	42	2642.151
#40	STRN3	27	5	32	1396.467
#41	PITX3	27	9	36	3630.718
#42	AFF1	27	8	35	2831.147
#43	NPAT	26	7	33	3904.798
#44	BRD8	26	11	37	2080.535
#45	FUBP1	26	2	28	767.973
#46	ELK1	26	5	31	452.507
#47	EPAS1	26	8	34	1579.471
#48	MLXIPL	25	1	26	9.602
#49	MITF	25	7	32	520.992
#50	TRIM22	25	10	35	2637.27
#51	RERE	25	6	31	1253.095
#52	AEBP1	24	6	30	436.448
#53	HLF	24	4	28	214.9
#54	ZFHX3	24	10	34	2607.752
#55	NFE2L1	24	9	33	510.642
#56	NR1I2	24	5	29	3211.468
#57	ETV4	24	9	33	4274.696
#58	KDM5B	23	7	30	1337.836
#59	NFATC1	23	7	30	1341.309
#60	BUD31	23	9	32	1986.774
#61	MYOG	23	4	27	542.903
#62	RARA	23	8	31	1211.526
#63	ZSCAN18	23	14	37	1134.353
#64	NR4A1	22	4	26	2702.811
#65	YEATS4	22	7	29	5624.855
#66	TCF15	22	4	26	222.958
#67	NR2F6	22	6	28	1200.253
#68	NFATC4	22	6	28	1486.129
#69	BTAF1	22	10	32	2336.501
#70	TCF21	22	8	30	593.971
#71	SNAI2	22	10	32	1091.321
#72	ELF4	22	14	36	2248.147
#73	MEF2C	21	5	26	967.512
#74	HSF2	21	12	33	1972.518
#75	RXRA	21	14	35	1209.592
#76	SPEN	21	5	26	360.269
#77	ZEB1	21	7	28	808.341
#78	MAFF	21	6	27	881.616
#79	ZNF277	21	13	34	2721.533
#80	EVX1	21	8	29	946.777
#81	FOSL2	21	3	24	430.727
#82	PBX1	21	8	29	3280.628
#83	HNRNPAB	20	12	32	4136.864
#84	FOSB	20	1	21	69.043
#85	SUPT4H1	20	12	32	1703.238
#86	XBP1	20	11	31	5390.73
#87	SOX4	20	9	29	1330.006
#88	PCGF2	20	12	32	1491.702
#89	CEBPB	20	7	27	1368.973
#90	SLC30A9	20	9	29	1761.34
#91	SNAPC5	20	12	32	2987.531
#92	RELA	20	8	28	742.429
#93	HCFC1	20	10	30	948.742
#94	ZNF189	19	9	28	794.101
#95	MZF1	19	12	31	2247.209
#96	ZKSCAN1	19	14	33	2247.468
#97	ELF1	19	3	22	728.719
#98	ZNF217	19	10	29	4566.515
#99	TCEAL1	19	7	26	1725.179
#100	NR2F2	19	14	33	4676.764
#101	PAX8	19	3	22	969.197
#102	SIM2	19	14	33	7141.619
#103	UBN1	18	1	19	126.388
#104	ZSCAN16	18	10	28	1287.333
#105	MTA1	18	11	29	1567.719
#106	JUNB	18	3	21	85.925
#107	CSDA	18	13	31	2185.867
#108	NFYB	18	10	28	352.637
#109	CNOT8	18	8	26	533.433
#110	PEG3	18	8	26	807.452
#111	RARG	17	4	21	116.76
#112	FOXO4	17	7	24	692.111
#113	ZBTB17	17	7	24	400.274
#114	SMAD3	17	7	24	1035.761
#115	STAT3	17	9	26	713.24
#116	CREBZF	17	9	26	4304.713
#117	MEIS3P1	17	10	27	843.862
#118	SUPT6H	17	11	28	1705.362
#119	ETV7	17	7	24	481.389
#120	PURA	17	10	27	3431.515
#121	EGR3	16	2	18	742.362
#122	TFCP2	16	7	23	1354.148
#123	TRPS1	16	8	24	961.996
#124	SOX10	16	9	25	1491.842
#125	HOXC11	16	11	27	236.996
#126	SATB1	16	11	27	3582.199
#127	CUX2	16	14	30	3050.151
#128	NOTCH1	16	11	27	4196.711
#129	SMAD4	16	13	29	1720.795
#130	HSF1	16	10	26	1948.995
#131	GATA3	15	8	23	470.742
#132	NKX3-1	15	11	26	1984.121
#133	YY1	15	7	22	3058.272
#134	SOX13	15	13	28	2506.447
#135	E2F5	15	12	27	1237.675
#136	HIF1A	15	8	23	400.327
#137	CDX2	15	11	26	560.209
#138	TFDP1	15	15	30	3188.616
#139	CEBPD	15	6	21	159.007
#140	ZNF148	15	7	22	706.503
#141	TULP4	15	8	23	280.705
#142	IRF5	15	5	20	215.201
#143	YBX1	15	12	27	3532.314
#144	MLX	14	15	29	1692.824
#145	HOXA9	14	11	25	1913.686
#146	REL	14	11	25	6513.49
#147	CUX1	14	12	26	2016.366
#148	ZNF219	14	15	29	966.835
#149	KLF4	14	6	20	935.923
#150	JUND	14	10	24	3301.011
#151	GABPB1	14	10	24	1355.884
#152	ESRRA	14	7	21	246.386
#153	BLZF1	14	7	21	410.79
#154	SNAPC2	14	9	23	292.9
#155	TRIM29	14	12	26	1276.178
#156	TP63	14	12	26	716.764
#157	PRRX2	14	9	23	3129.902
#158	NR2F1	14	17	31	2970.233
#159	ZGPAT	14	10	24	2404.116
#160	KLF7	14	13	27	1041.372
#161	TAF10	14	17	31	1200.703
#162	CREB3L1	14	18	32	1369.54
#163	KLF10	14	5	19	870.451
#164	ZNF207	13	7	20	790.688
#165	LHX3	13	13	26	902.392
#166	NFIC	13	7	20	926.616
#167	ECSIT	13	11	24	1820.836
#168	NR1H2	13	13	26	3291.99
#169	ETV2	13	12	25	1487.282
#170	NFYC	13	8	21	8291.783
#171	ADNP	13	13	26	2975.917
#172	HSF4	13	12	25	1139.598
#173	USF2	13	8	21	476.422
#174	RUNX1T1	13	10	23	439.289
#175	SRF	13	9	22	3531.033
#176	RBCK1	13	11	24	996.792
#177	LASS6	13	11	24	1755.156
#178	ZNF35	13	8	21	2426.066
#179	TCF7L2	13	14	27	2326.806
#180	SREBF2	13	13	26	4157.59
#181	FOXP3	12	6	18	642.96
#182	NRL	12	14	26	3857.015
#183	MAF	12	13	25	770.858
#184	RNF4	12	13	25	1873.633
#185	ETS2	12	12	24	2557.776
#186	ISL1	12	9	21	2150.291
#187	LMO4	12	8	20	3581.603
#188	CREBBP	12	8	20	946.151
#189	NR4A3	12	4	16	191.792
#190	BHLHE40	12	12	24	5798.68
#191	HOXB13	12	16	28	2303.034
#192	GATAD1	12	8	20	1227.193
#193	HDAC2	12	13	25	1257.766
#194	TSC22D4	12	13	25	977.045
#195	PHF1	11	15	26	862.819
#196	C2orf3	11	14	25	748.448
#197	LASS2	11	11	22	3185.21
#198	ZNF236	11	2	13	30.707
#199	HNF1A	11	7	18	855.833
#200	NFKB1	11	12	23	1429.592
#201	NR3C2	11	11	22	1082.754
#202	HNRNPK	11	18	29	1250.968
#203	HDAC1	11	11	22	430.013
#204	CTBP1	11	14	25	1606.63
#205	MYBL2	11	18	29	652.874
#206	FOXO1	11	14	25	2456.381
#207	ZBTB38	11	11	22	1022.911
#208	ZNF444	11	14	25	4478.756
#209	CREBL2	11	16	27	1260.594
#210	NFIL3	11	7	18	179.19
#211	SNAPC4	11	14	25	610.022
#212	HOXB1	11	7	18	602.997
#213	ESRRG	11	11	22	853.492
#214	PLSCR1	11	9	20	980.135
#215	SOX15	11	4	15	26.833
#216	DMTF1	10	8	18	822.072
#217	FOSL1	10	8	18	1000.021
#218	KDM5A	10	11	21	838.416
#219	FOXD1	10	11	21	1113.88
#220	TCF3	10	9	19	954.984
#221	HNF1B	10	11	21	3643.444
#222	FOS	10	8	18	2731.335
#223	PTTG1	10	16	26	2624.566
#224	PLAG1	10	14	24	1272.865
#225	ENO1	10	6	16	1986.628
#226	BHLHE41	10	11	21	449.667
#227	POU2F2	10	10	20	351.732
#228	MSRB2	10	14	24	2670.582
#229	NR1D2	10	10	20	2178.254
#230	SCAND1	10	10	20	1303.085
#231	FLI1	10	10	20	845.177
#232	TCF4	10	13	23	1327.621
#233	GATA6	10	10	20	117.404
#234	KLF9	10	18	28	3385.372
#235	MAX	9	10	19	2594.264
#236	REST	9	13	22	2167.409
#237	JUN	9	12	21	714.027
#238	IRF6	9	13	22	2978.333
#239	STAT6	9	8	17	889.042
#240	MMP14	9	7	16	433.273
#241	TBX4	9	13	22	2043.951
#242	NFIX	9	7	16	791.86
#243	TBX2	9	18	27	2203.805
#244	NR4A2	9	12	21	4110.478
#245	FOXA2	9	8	17	1433.59
#246	CBFB	9	14	23	1555.9
#247	NFE2L2	9	14	23	3665.484
#248	ZNF91	9	14	23	1672.316
#249	TGIF1	9	13	22	3156.325
#250	RORC	9	11	20	1232.001
#251	SOX9	9	19	28	3661.413
#252	ZNF83	9	12	21	377.892
#253	ZFP36L2	9	15	24	415.452
#254	NFKB2	9	9	18	1343.052
#255	AHR	9	14	23	1959.823
#256	TFAP2C	9	13	22	1419.435
#257	ZNF287	9	9	18	596.498
#258	HMG20B	9	11	20	2696.13
#259	ERG	8	9	17	2734.627
#260	ATF3	8	8	16	239.129
#261	KLF6	8	13	21	3618.673
#262	ELF3	8	16	24	3200.723
#263	FEV	8	17	25	4172.743
#264	MECOM	8	12	20	1114.918
#265	ETV5	8	15	23	1053.271
#266	HOXD13	8	14	22	1722.978
#267	SREBF1	8	11	19	1571.076
#268	DRAP1	8	13	21	2497.326
#269	PBX3	8	18	26	7422.458
#270	NFATC3	8	12	20	1089.242
#271	ERF	8	10	18	1548.268
#272	BACH1	8	12	20	1050.113
#273	ZNF45	8	11	19	2451.629
#274	GLI3	8	9	17	3814.524
#275	E4F1	8	15	23	1506.638
#276	RXRB	8	9	17	2633.646
#277	SATB2	8	19	27	1564.935
#278	TSHZ2	8	16	24	2064.372
#279	AATF	8	13	21	765.425
#280	TBP	8	13	21	803.03
#281	TEF	8	15	23	1953.114
#282	ELK4	8	12	20	1107.559
#283	HAND2	8	8	16	618.093
#284	NOLC1	7	17	24	1766.085
#285	ARNT	7	12	19	993.703
#286	POU6F1	7	11	18	486.537
#287	ZNF24	7	6	13	941.583
#288	GTF2H3	7	16	23	1924.738
#289	TCF20	7	19	26	3686.499
#290	HOXC8	7	12	19	1480.357
#291	CBFA2T3	7	13	20	1712.944
#292	STAT5B	7	5	12	621.635
#293	MGA	7	10	17	470.107
#294	RCAN1	7	11	18	1375.294
#295	DBP	7	14	21	1532.821
#296	FOXK2	7	17	24	571.242
#297	HOXD11	7	11	18	2084.179
#298	TBX1	7	10	17	644.51
#299	HOPX	7	19	26	2620.305
#300	HINFP	7	14	21	981.844
#301	BCL3	7	10	17	860.673
#302	GATA2	7	18	25	1111.232
#303	MNT	7	13	20	1660.056
#304	ZFP36L1	7	11	18	1662.028
#305	SMAD1	7	13	20	1291.77
#306	BCL6	7	11	18	1092.297
#307	DLX2	7	19	26	1346.449
#308	FOXJ1	7	16	23	493.148
#309	SOX18	7	17	24	1286.026
#310	KLF2	7	7	14	3936.662
#311	EHF	6	15	21	2735.659
#312	ELF2	6	19	25	1111.565
#313	IRX4	6	14	20	1296
#314	POU3F1	6	7	13	561.855
#315	E2F3	6	12	18	1530.709
#316	NFAT5	6	9	15	1039.831
#317	MEF2D	6	13	19	878.851
#318	TFDP2	6	15	21	1903.162
#319	HCLS1	6	8	14	183.946
#320	KLF5	6	13	19	576.826
#321	TFEB	6	19	25	1035.094
#322	ELF5	6	15	21	3231.37
#323	ZNF434	6	13	19	311.98
#324	LZTR1	6	16	22	1057.477
#325	ZNF187	6	13	19	2811.373
#326	GAS7	6	17	23	680.96
#327	ARID4A	6	9	15	116.77
#328	SOLH	6	10	16	519.839
#329	TWIST1	6	21	27	1571.94
#330	TSC22D2	6	16	22	1903.472
#331	TAF4	6	16	22	461.795
#332	HOXA5	6	18	24	3460.109
#333	SCML1	6	13	19	924.999
#334	ZNF167	6	10	16	1478.035
#335	IRF3	6	17	23	612.187
#336	SMAD6	6	11	17	956.251
#337	BACH2	6	9	15	317.261
#338	CREB3	6	9	15	383.451
#339	TFCP2L1	6	8	14	1678.842
#340	RFXANK	6	8	14	110.221
#341	NCOR1	6	13	19	1801.696
#342	SIX2	6	13	19	3002.813
#343	SOX21	5	15	20	674.223
#344	MYCL1	5	16	21	1159.674
#345	IKZF1	5	11	16	419.765
#346	CDKN2A	5	16	21	1985.439
#347	MSL3	5	14	19	519.273
#348	ETV1	5	13	18	36466.122
#349	CREM	5	15	20	1728.644
#350	ZNF323	5	15	20	3092.53
#351	TFAP2A	5	22	27	2359.137
#352	IRF7	5	17	22	2960.532
#353	HEY1	5	10	15	152.391
#354	HIF3A	5	15	20	534.645
#355	CREB1	5	11	16	463.12
#356	FOXM1	5	13	18	1346.36
#357	KLF11	5	12	17	683.266
#358	NFYA	5	20	25	1036.39
#359	RORA	5	12	17	598.692
#360	GCFC1	5	11	16	481.646
#361	CNBP	5	14	19	2392.965
#362	TAF12	5	10	15	177.366
#363	CLOCK	5	6	11	76.971
#364	HOXD10	5	13	18	376.081
#365	TCF25	5	16	21	3366.303
#366	ZFPM2	5	8	13	58.335
#367	HMGB2	5	17	22	1438.56
#368	ZHX3	5	11	16	978.629
#369	ZNF93	5	8	13	1707.77
#370	SOX12	5	13	18	711.562
#371	PBX2	5	8	13	64.285
#372	ZNF238	5	23	28	2174.415
#373	ESR1	5	16	21	4671.763
#374	GATAD2A	4	13	17	815.017
#375	RFX5	4	9	13	316.833
#376	PA2G4	4	12	16	252.726
#377	WNT5A	4	26	30	2000.305
#378	PLAGL2	4	15	19	1126.413
#379	PFDN1	4	12	16	1712.75
#380	GTF2I	4	17	21	5362.695
#381	KLF3	4	21	25	890.476
#382	NPAS2	4	17	21	2177.841
#383	HOXC4	4	12	16	1112.359
#384	ZSCAN12	4	13	17	2120.986
#385	HMGA1	4	15	19	1622.063
#386	CBFA2T2	4	11	15	698.952
#387	TADA3	4	14	18	615.975
#388	SCMH1	4	15	19	1016.062
#389	PRDM2	4	14	18	1607.884
#390	DDIT3	4	12	16	3102.634
#391	TCF7	4	14	18	615.547
#392	MTF1	4	16	20	1518.682
#393	UBP1	4	13	17	74.67
#394	AR	4	14	18	1332.667
#395	E2F6	4	12	16	307.246
#396	ZNF133	4	18	22	1428.787
#397	ATF5	4	20	24	910.878
#398	RELB	4	12	16	962.859
#399	MEOX1	4	12	16	4497.75
#400	RUNX1	4	14	18	737.464
#401	CTCF	4	15	19	517.353
#402	TGIF2	4	11	15	322.439
#403	TEAD4	4	9	13	1380.741
#404	BATF	4	19	23	684.448
#405	STAT1	4	11	15	1137.109
#406	ZNF281	4	16	20	1061.755
#407	HHEX	4	12	16	5074.261
#408	ZNF500	4	14	18	149.049
#409	MLLT10	4	15	19	736.06
#410	ZNF394	4	10	14	671.893
#411	ZIC3	4	14	18	12679.193
#412	MNX1	3	17	20	264.524
#413	PKNOX2	3	16	19	111.065
#414	RUNX3	3	15	18	176.569
#415	STAT2	3	10	13	589.531
#416	NR2C1	3	10	13	1130.306
#417	CEBPA	3	16	19	333.8
#418	SLC2A4RG	3	18	21	368.237
#419	TCFL5	3	18	21	391.31
#420	ZNF131	3	16	19	347.808
#421	ZNF268	3	13	16	338.964
#422	SOX17	3	11	14	790.815
#423	MAFB	3	14	17	195.308
#424	CNOT7	3	13	16	2646.918
#425	TP53	3	16	19	885.035
#426	TSC22D3	3	17	20	1021.861
#427	BATF3	3	12	15	464.704
#428	HIC1	3	16	19	474.083
#429	IRX5	3	15	18	970.801
#430	HMGB1	3	13	16	1030.114
#431	SCML2	3	16	19	1823.658
#432	PITX1	3	17	20	625.895
#433	EGR2	3	7	10	523.863
#434	NFIB	3	17	20	792.876
#435	HOXA3	3	13	16	53.944
#436	BTG2	3	18	21	1149.801
#437	GLI2	3	18	21	522.121
#438	EDF1	3	9	12	1155.852
#439	FOXC1	3	13	16	463.664
#440	MYC	2	13	15	80.692
#441	CSRNP2	2	10	12	782.313
#442	SPIB	2	11	13	87.662
#443	HMBOX1	2	13	15	306.893
#444	NR1H3	2	10	12	362.676
#445	ZNF75D	2	15	17	671.992
#446	CITED2	2	22	24	359.95
#447	MSX2	2	10	12	288.403
#448	ARNT2	2	15	17	756.772
#449	IRF9	2	18	20	413.066
#450	ZFHX4	2	17	19	2040.159
#451	HES1	2	28	30	2928.259
#452	HOXA10	2	13	15	130.89
#453	ZNF232	2	15	17	103.958
#454	ZXDC	2	14	16	202.43
#455	CITED1	2	16	18	216.723
#456	RARB	2	11	13	1163.13
#457	HOXB7	2	13	15	1826.506
#458	TBX3	2	18	20	1950.34
#459	MAFG	2	11	13	312.002
#460	SMAD5	2	7	9	267.446
#461	ZBTB48	2	17	19	576.255
#462	HOXD1	2	9	11	578.543
#463	ZNF3	2	16	18	185.767
#464	ZHX2	2	15	17	95.156
#465	GRHL2	2	18	20	129.305
#466	MSX1	2	15	17	610.143
#467	FBXW7	2	19	21	1097.437
#468	HOXA11	1	20	21	86.9
#469	MYF6	1	13	14	1064.895
#470	ATF4	1	13	14	281.18
#471	HR	1	16	17	51.267
#472	ADNP2	1	17	18	1771.874
#473	SIX5	1	10	11	58.425
#474	FOXI1	1	17	18	1631.997
#475	IRF1	1	13	14	69.632
#476	PRRX1	1	18	19	10636.759
#477	ATF6B	1	18	19	962.08
#478	FOXG1	1	16	17	3882.068
#479	CTNNB1	1	11	12	212.399
#480	SLC26A3	1	15	16	110.933
#481	ATF6	1	18	19	373.354
#482	GTF2H4	1	11	12	457.018
#483	PPARG	1	13	14	344.199
#484	IRF8	1	16	17	36.629
#485	HOXB2	1	16	17	399.736
#486	TSC22D1	1	14	15	80.36
#487	IRF2	1	14	15	54.009
#488	ASCL1	1	16	17	56.975
#489	FOXJ2	1	9	10	490.013
#490	TAF6	0	18	18	0
#491	LEF1	0	22	22	0
#492	PHTF1	0	17	17	0
#493	PKNOX1	0	13	13	0
#494	EGR1	0	11	11	0
#495	HEY2	0	16	16	0
#496	HIRA	0	16	16	0
#497	CIR1	0	18	18	0
#498	EGR4	0	13	13	0
#499	SIX1	0	18	18	0
#500	FOXF2	0	15	15	0