Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NKX3-1	34	6	40	688.753
#2	MTF1	32	5	37	914.429
#3	EHF	30	5	35	916.275
#4	MYC	26	7	33	3076.478
#5	E2F7	25	1	26	30.41
#6	GLI3	25	4	29	582.219
#7	SP1	24	3	27	453.389
#8	GATA3	24	3	27	164.808
#9	PHTF1	24	4	28	165.046
#10	HEY1	23	8	31	840.029
#11	PGR	23	5	28	3138.874
#12	BHLHE40	23	4	27	2218.162
#13	FOXJ1	23	3	26	414.049
#14	HOXD9	22	8	30	5760.477
#15	AHR	22	2	24	706.398
#16	ESR1	22	2	24	119.612
#17	HOXB6	21	3	24	1691.915
#18	IRF1	21	6	27	507.582
#19	HHEX	21	7	28	3517.661
#20	MYCL1	20	4	24	537.391
#21	E2F4	20	10	30	5178.661
#22	PRRX2	19	8	27	2238.562
#23	ETV4	19	7	26	568.285
#24	ZNF238	18	2	20	231.887
#25	MEIS1	18	7	25	925.773
#26	LHX2	18	5	23	134.71
#27	CSRNP1	18	7	25	3876.129
#28	ETS2	17	6	23	1473.027
#29	NR4A2	17	5	22	613.963
#30	ELF5	17	6	23	271.003
#31	SCAND1	17	8	25	4107.052
#32	RARG	17	4	21	584.376
#33	LHX6	16	3	19	657.404
#34	CREB1	16	9	25	1561.76
#35	GATA6	16	7	23	2143.69
#36	GATAD2B	16	7	23	3100.855
#37	KLF11	16	10	26	5313.624
#38	CREB3L2	16	7	23	351.373
#39	FOXF2	15	8	23	2520.681
#40	HEY2	15	8	23	659.921
#41	HOXB5	15	11	26	5793.105
#42	SIX5	15	9	24	1435.565
#43	HOXB2	15	6	21	482.545
#44	SPEN	15	5	20	427.384
#45	HES6	15	6	21	2429.864
#46	TSC22D2	15	10	25	2700.261
#47	DLX1	15	5	20	493.547
#48	AFF4	15	6	21	4629.365
#49	ZSCAN2	14	7	21	1889.583
#50	ZNF207	14	2	16	337.166
#51	POU4F3	14	12	26	2619.194
#52	ZEB2	14	7	21	1989.207
#53	TWIST1	14	5	19	488.633
#54	GSX2	14	8	22	2553.787
#55	FOXQ1	14	6	20	290.435
#56	HOXB3	14	5	19	1514.96
#57	ONECUT2	14	5	19	729.91
#58	KLF3	14	5	19	702.783
#59	NFAT5	14	7	21	1726.045
#60	EBF1	14	5	19	2446.917
#61	ZNF483	13	8	21	2116.769
#62	NFIA	13	7	20	1369.77
#63	NR1D2	13	6	19	2372.178
#64	TCF7	13	7	20	4806.109
#65	RFX3	13	8	21	717.107
#66	HOXA1	13	9	22	243.972
#67	ZIC2	13	10	23	1924.438
#68	FOXH1	13	7	20	2846.642
#69	SMAD5	13	5	18	2623.059
#70	HSF1	13	2	15	487.347
#71	PITX1	13	16	29	3442.573
#72	HOXA2	13	7	20	511.278
#73	PPARG	13	5	18	2193.643
#74	POU3F1	13	7	20	993.082
#75	SMAD6	13	9	22	1208.133
#76	ZEB1	13	4	17	3098.11
#77	FOXA1	13	3	16	929.407
#78	NOTCH1	13	11	24	1975.946
#79	TADA3	13	6	19	5792.474
#80	BTG2	13	6	19	711.283
#81	SOX1	12	10	22	2062.066
#82	NFIX	12	4	16	670.174
#83	BATF2	12	8	20	1558.27
#84	ZNF396	12	6	18	1715.097
#85	HOXD11	12	5	17	2035.169
#86	SPI1	12	5	17	220.758
#87	TP63	12	7	19	282.435
#88	MAF	12	13	25	1071.304
#89	ARNTL2	12	9	21	910.178
#90	CREB3L4	12	5	17	246.902
#91	KLF1	12	8	20	4714.952
#92	NFKB2	12	9	21	1984.981
#93	HNF4G	12	9	21	9557.031
#94	ATOH1	12	10	22	1849.149
#95	ZXDC	12	6	18	1462.075
#96	ETV6	12	16	28	905.253
#97	ZNF277	12	8	20	1360.214
#98	MSX2	12	7	19	4243.498
#99	BCL11B	12	6	18	563.986
#100	FOXA3	12	9	21	2171.88
#101	MEF2C	12	6	18	585.148
#102	SOX21	12	12	24	4150.683
#103	FOXP4	12	8	20	5382.302
#104	TLX2	11	8	19	1569.574
#105	SMAD3	11	12	23	2429.335
#106	L3MBTL4	11	8	19	1174.218
#107	MGA	11	10	21	1472.894
#108	TGIF2	11	7	18	1861.157
#109	MAFF	11	8	19	816.606
#110	TSHZ2	11	13	24	8541.063
#111	SIX2	11	11	22	1165.627
#112	EGR3	11	8	19	362.57
#113	CEBPA	11	6	17	3497.561
#114	TEAD2	11	7	18	828.138
#115	MXD1	11	14	25	1591.357
#116	RORC	11	8	19	4325.063
#117	MYCN	11	9	20	1424.452
#118	ZNF165	11	13	24	3676.94
#119	GSX1	11	7	18	1767.898
#120	ZFP36L1	11	9	20	1285.17
#121	HOXB7	11	6	17	546.135
#122	NR2E1	11	9	20	6809.033
#123	CITED2	11	15	26	1646.118
#124	SOX17	11	7	18	892.316
#125	USF1	11	10	21	2220.278
#126	MLL	11	8	19	4177.619
#127	TP53	11	8	19	6827.361
#128	HMGA2	11	9	20	2616.239
#129	NR2F6	11	5	16	475.553
#130	ELF1	11	7	18	1071.371
#131	SNAI2	11	2	13	60.708
#132	PROX1	11	9	20	2828.9
#133	NFIB	11	9	20	2274.755
#134	RELA	11	7	18	799.535
#135	ZNF236	11	7	18	1595.46
#136	ZNF83	11	14	25	4408.709
#137	HOXA9	10	16	26	3142.294
#138	ZFP36L2	10	8	18	1310.897
#139	FOS	10	6	16	231.165
#140	EPAS1	10	12	22	2411.25
#141	HOXA3	10	11	21	1443.689
#142	RCAN1	10	10	20	3072.239
#143	SCRT1	10	13	23	1340.076
#144	ZSCAN12	10	11	21	3828.576
#145	TFAP2C	10	8	18	608.31
#146	AHCTF1	10	5	15	758.072
#147	TAF10	10	8	18	1765.25
#148	BARHL1	10	6	16	452.229
#149	FOXC1	10	11	21	2655.612
#150	SCAND2	10	6	16	1712.561
#151	TCF15	10	10	20	2943.928
#152	BCL6	10	8	18	360.862
#153	JUND	10	8	18	877.135
#154	ARNT	10	7	17	1544.627
#155	FOSL2	10	9	19	880.398
#156	NR4A3	10	9	19	4730.184
#157	IRF8	10	5	15	1214.324
#158	POU4F1	10	8	18	2371.29
#159	FOXK2	10	6	16	1631.347
#160	STRN3	10	6	16	594.984
#161	FOXR2	10	5	15	5591.692
#162	GATA1	10	9	19	1419.45
#163	NFYC	10	5	15	953.086
#164	CREB3L3	10	10	20	4159.643
#165	SUPT6H	10	4	14	283.452
#166	TBX4	9	10	19	2436.578
#167	STAT1	9	6	15	499.261
#168	SMAD9	9	10	19	605.696
#169	ZSCAN18	9	9	18	1224.149
#170	HMGB2	9	7	16	998.573
#171	MYT1L	9	8	17	1820.906
#172	ZNF397	9	9	18	1929.979
#173	PURB	9	6	15	1209.666
#174	AR	9	9	18	1048.142
#175	NFYA	9	10	19	2455.647
#176	FOXJ2	9	10	19	1928.908
#177	NPAT	9	12	21	2677.908
#178	ZNF438	9	7	16	1033.34
#179	TBX5	9	13	22	3468.212
#180	NFIC	9	8	17	1154.475
#181	FOXR1	9	12	21	7041.801
#182	POU1F1	9	6	15	1196.251
#183	TAF4B	9	11	20	5165.187
#184	GLIS3	9	7	16	577.836
#185	TFE3	9	8	17	1112.642
#186	POU5F2	9	8	17	2519.198
#187	NANOGNB	9	2	11	1025.504
#188	TRPS1	9	14	23	1531.277
#189	NFATC3	9	13	22	3316.619
#190	HMG20B	9	9	18	1163.875
#191	FLI1	9	8	17	897.024
#192	RARB	9	7	16	839.302
#193	TRIM22	9	10	19	301.238
#194	ZNF132	9	8	17	370.22
#195	EN1	9	6	15	1451.339
#196	RFX1	9	12	21	3754.223
#197	RXRG	9	5	14	1420.928
#198	SOX7	9	5	14	1515.183
#199	TBX20	9	8	17	989.147
#200	TRERF1	9	9	18	1641.681
#201	THRA	9	10	19	1202.615
#202	FOXD3	9	12	21	2001.806
#203	NR2E3	9	8	17	1278.101
#204	CTBP1	9	6	15	1802.513
#205	HOXB9	9	10	19	541.409
#206	TFEC	8	8	16	1518.772
#207	GBX2	8	6	14	1081.36
#208	NR2F1	8	6	14	378.768
#209	NKX2-5	8	9	17	1739.553
#210	SOX5	8	7	15	642.112
#211	TULP4	8	6	14	424.13
#212	SIN3A	8	10	18	2184.075
#213	TFAP2B	8	8	16	897.663
#214	ZNF3	8	9	17	3117.603
#215	REL	8	12	20	2147.903
#216	FOXO3	8	4	12	867.912
#217	SPDEF	8	11	19	4197.582
#218	VTN	8	9	17	673.205
#219	ZKSCAN1	8	11	19	839.742
#220	DMBX1	8	7	15	1519.219
#221	RUNX1T1	8	10	18	1317.631
#222	CRX	8	10	18	1710.185
#223	SIM1	8	8	16	270.634
#224	CSRNP3	8	9	17	2759.632
#225	NR6A1	8	7	15	1671.825
#226	ISL1	8	9	17	1120.149
#227	LMX1A	8	7	15	1587.634
#228	KLF6	8	12	20	1329.333
#229	OTX1	8	6	14	1085.824
#230	FOXN4	8	6	14	1028.252
#231	ASCL2	8	7	15	1262.826
#232	RB1	8	10	18	1057.351
#233	CLOCK	8	9	17	854.831
#234	NR3C2	8	10	18	1551.608
#235	EGR1	8	9	17	752.28
#236	CREBZF	8	9	17	1036.604
#237	HAND2	8	10	18	1816.318
#238	TLX3	8	7	15	1401.553
#239	IRX4	8	11	19	936.405
#240	PPARA	8	7	15	968.337
#241	ESRRG	8	8	16	2362.051
#242	MLLT10	8	10	18	2174.352
#243	POU2F2	8	8	16	1046.732
#244	TBX1	8	8	16	857.997
#245	ZNF175	8	7	15	1797.784
#246	MBD1	8	8	16	399.157
#247	KLF5	8	8	16	400.963
#248	CSDA	8	10	18	4314.434
#249	TFAP2D	8	7	15	1191.279
#250	ZFP42	8	9	17	1665.735
#251	HIC1	8	9	17	734.083
#252	NPAS2	8	6	14	357.431
#253	GATAD1	8	6	14	1021.51
#254	MYNN	8	6	14	1334.428
#255	BACH2	8	7	15	4887.352
#256	SOX11	7	11	18	1472.447
#257	NR2F2	7	13	20	968.843
#258	THRB	7	8	15	522.991
#259	ZBTB38	7	8	15	1207.6
#260	MYT1	7	9	16	1399.556
#261	TCF4	7	9	16	1299.968
#262	ERG	7	10	17	699.938
#263	ELK4	7	12	19	1254.262
#264	IRF6	7	8	15	872.554
#265	NEUROD2	7	10	17	2975.864
#266	RUNX1	7	7	14	1326.116
#267	MECOM	7	6	13	912.664
#268	ATF6B	7	12	19	1607.709
#269	SMAD2	7	12	19	2267.969
#270	RORA	7	7	14	686.292
#271	C11orf9	7	12	19	2055.214
#272	FOXE1	7	9	16	1809.727
#273	PAX3	7	9	16	3446.27
#274	RBPJL	7	10	17	1030.077
#275	MYF5	7	7	14	1350.567
#276	DLX2	7	8	15	1183.634
#277	NEUROD1	7	9	16	1517.322
#278	ATF2	7	10	17	1287.19
#279	ZSCAN5A	7	6	13	675.514
#280	ZNF117	7	17	24	738.933
#281	HOXB8	7	12	19	1995.113
#282	NR1I3	7	6	13	1986.381
#283	PDX1	7	7	14	1424.691
#284	HES1	7	9	16	1533.99
#285	NR2C1	7	10	17	709.748
#286	PAX5	7	14	21	1949.591
#287	TCF25	7	10	17	1348.02
#288	FOXP2	7	10	17	1938.533
#289	HOXA13	7	8	15	852.586
#290	MITF	7	11	18	566.355
#291	LHX8	7	13	20	1805.947
#292	ZNF287	7	7	14	1014.936
#293	GCM1	7	10	17	1783.031
#294	SNAPC4	7	8	15	1757.014
#295	SATB1	7	10	17	638.394
#296	SP3	7	11	18	2522.676
#297	NR5A2	7	12	19	2052.147
#298	CBFA2T3	7	5	12	1329.74
#299	RARA	7	9	16	833.721
#300	CREM	7	8	15	1488.694
#301	NFE2	7	7	14	853.773
#302	ZNF91	7	8	15	1471.866
#303	SIX4	7	9	16	1112.765
#304	SOX2	7	8	15	707.725
#305	STAT4	7	14	21	1310.469
#306	MLX	7	9	16	2335.666
#307	TAF4	7	9	16	1608.267
#308	ZNF81	7	12	19	1959.184
#309	HOXD1	6	6	12	656.058
#310	TAL1	6	12	18	1081.221
#311	ALS2CR8	6	10	16	1404.075
#312	MEOX1	6	7	13	652.462
#313	NFATC4	6	4	10	511.097
#314	KDM5A	6	5	11	886.702
#315	HNF1B	6	10	16	939.733
#316	ZFHX4	6	7	13	827.359
#317	TCF7L2	6	6	12	912.541
#318	BRD8	6	13	19	1237.727
#319	ZNF155	6	7	13	3333.231
#320	PRDM1	6	11	17	1256.966
#321	ESRRB	6	10	16	1531.265
#322	BNC1	6	9	15	717.181
#323	NR1I2	6	6	12	596.471
#324	BHLHE41	6	4	10	2484.512
#325	DLX6	6	10	16	1839.322
#326	CUX2	6	9	15	5142.284
#327	HOPX	6	8	14	1500.191
#328	ZNF85	6	9	15	921.95
#329	E2F2	6	12	18	2251.182
#330	NKX6-1	6	12	18	1644.434
#331	TCF3	6	7	13	1064.982
#332	NKX2-1	6	9	15	1306.855
#333	SOX9	6	8	14	533.065
#334	PRDM2	6	12	18	2185.531
#335	RORB	6	6	12	697.942
#336	GAS7	6	9	15	1169.963
#337	SP140	6	9	15	842.901
#338	FOXE3	6	11	17	3847.152
#339	SOX4	6	14	20	1066.213
#340	HDX	6	13	19	1464.536
#341	FOXD4	6	6	12	530.147
#342	WT1	6	11	17	1895.37
#343	PAX4	6	7	13	896.857
#344	ALX3	6	8	14	1678.857
#345	IRF4	6	12	18	1861.744
#346	ZNF169	6	8	14	1515.497
#347	ISX	6	11	17	1455.153
#348	TGIF2LY	6	5	11	401.993
#349	ZFPM2	6	7	13	174.013
#350	PTH	6	6	12	874.848
#351	POU6F1	6	11	17	1847.954
#352	ZNF496	5	12	17	1921.163
#353	ZNF24	5	7	12	1683.038
#354	TBX15	5	11	16	741.661
#355	NRL	5	10	15	1156.432
#356	ZNF219	5	8	13	704.957
#357	PKNOX2	5	11	16	1726.177
#358	SLC26A3	5	11	16	1496.93
#359	KDM5B	5	9	14	1053.561
#360	LEF1	5	14	19	2145.074
#361	POU4F2	5	6	11	632.738
#362	TFCP2L1	5	9	14	360.453
#363	ISL2	5	11	16	1255.694
#364	BARX1	5	9	14	858.238
#365	ETV5	5	9	14	853.647
#366	FUBP1	5	12	17	1520.471
#367	ZFP37	5	7	12	1934.519
#368	NR0B1	5	8	13	518.587
#369	GATA4	5	14	19	2675.938
#370	TBR1	5	15	20	1365.496
#371	ZNF628	5	11	16	1350.114
#372	MIXL1	5	9	14	684.997
#373	FOXL2	5	11	16	938.735
#374	TFAP2E	5	8	13	483.66
#375	BUD31	5	12	17	1551.049
#376	PEG3	5	7	12	953.185
#377	KLF9	5	9	14	872.691
#378	SP4	5	7	12	1008.186
#379	RUNX2	5	10	15	915.184
#380	MSX1	5	8	13	1107.347
#381	ESR2	5	11	16	1764.269
#382	HMX1	5	14	19	3297.542
#383	ZIC3	5	7	12	444.403
#384	PITX3	5	13	18	1103.253
#385	ETS1	5	9	14	1047.349
#386	ZNF154	5	6	11	456.654
#387	FOXG1	5	8	13	810.82
#388	HOXC5	5	9	14	1128.947
#389	HOXD13	5	9	14	1480.47
#390	OLIG2	5	9	14	1341.441
#391	ASCL1	5	11	16	1175.585
#392	VSX1	5	11	16	927.939
#393	TLX1	5	16	21	1586.353
#394	TBX10	5	8	13	675.433
#395	POU2F1	5	11	16	1001.25
#396	VENTX	5	5	10	376.407
#397	HNF4A	5	7	12	575.749
#398	SIX1	5	5	10	284.444
#399	KLF16	5	11	16	1469.45
#400	HOXD10	5	10	15	546.005
#401	FOXN1	5	10	15	1207.617
#402	HCFC1	5	10	15	878.744
#403	SIM2	5	10	15	3564.605
#404	PLSCR1	5	7	12	311.873
#405	ZNF167	4	9	13	688.114
#406	FEV	4	11	15	1450.344
#407	TFAP2A	4	10	14	638.835
#408	ZNF135	4	5	9	288.744
#409	FOXI1	4	5	9	811.498
#410	OTX2	4	12	16	992.226
#411	FOXP3	4	8	12	1183.94
#412	LHX5	4	3	7	466.232
#413	TCF21	4	8	12	510.323
#414	FOXC2	4	11	15	1913.023
#415	TSC22D1	4	11	15	957.647
#416	EVX1	4	8	12	814.266
#417	RUNX3	4	6	10	630.444
#418	PAX8	4	12	16	1302.166
#419	ATF7	4	8	12	1051.918
#420	PBX3	4	10	14	1097.17
#421	MEIS2	4	9	13	116.602
#422	HESX1	4	8	12	1495.136
#423	GATA5	4	10	14	515.474
#424	FOXA2	4	11	15	740.63
#425	ZNF449	4	11	15	1008.006
#426	KLF2	4	12	16	1374.489
#427	PPARD	4	10	14	909.752
#428	SOX6	4	8	12	958.262
#429	ZNF92	4	10	14	1083.408
#430	ZNF148	4	5	9	320.709
#431	MYOG	4	13	17	1969.373
#432	IKZF1	4	12	16	777.564
#433	CBL	4	9	13	907.859
#434	ELK1	4	6	10	736.11
#435	NKX2-3	4	8	12	580.057
#436	NFATC1	4	7	11	719.175
#437	ZSCAN20	4	9	13	958.987
#438	ATF5	4	10	14	5078.059
#439	CREB5	3	6	9	253.897
#440	TFCP2	3	8	11	1789.137
#441	FOXO1	3	13	16	517.519
#442	FOXN3	3	8	11	779.584
#443	SOX30	3	5	8	1474.872
#444	HOXA11	3	3	6	161.934
#445	FOXB1	3	10	13	532.512
#446	ZNF157	3	7	10	813.145
#447	SIX6	3	8	11	639.686
#448	MMP14	3	9	12	426.761
#449	ZNF192	3	7	10	598.072
#450	CITED1	3	11	14	292.654
#451	FOXK1	3	8	11	1168.208
#452	HMX2	3	10	13	506.84
#453	ELF3	3	6	9	172.623
#454	CDX2	3	13	16	1131.518
#455	LMO4	3	8	11	420.131
#456	LHX4	3	5	8	539.291
#457	EGR2	3	6	9	74.338
#458	NR1H4	3	12	15	531.361
#459	KCNH8	3	10	13	615.219
#460	HOXB13	3	9	12	704.782
#461	POU3F3	3	9	12	430.883
#462	POU6F2	3	8	11	372.827
#463	ZNF71	3	8	11	433.123
#464	ST18	3	10	13	585.37
#465	TEF	3	11	14	626.76
#466	SALL1	3	7	10	469.656
#467	POU3F2	3	14	17	787.072
#468	SIX3	3	8	11	849.907
#469	ZBTB48	3	10	13	448.476
#470	KLF12	3	9	12	715.888
#471	HOXD3	2	8	10	769.487
#472	WNT5A	2	13	15	443.809
#473	LASS5	2	10	12	485.843
#474	CEBPD	2	10	12	326.172
#475	LHX3	2	10	12	387.629
#476	TBX3	2	11	13	352.761
#477	HIF3A	2	13	15	1134.508
#478	MEOX2	2	11	13	412.063
#479	LZTS1	2	9	11	239.799
#480	SOX10	2	8	10	253.101
#481	IKZF3	2	9	11	702.406
#482	HLF	2	14	16	322.975
#483	PURA	2	12	14	512.608
#484	ZKSCAN3	2	5	7	214.462
#485	ETV7	2	7	9	296.619
#486	CREB3L1	2	12	14	310.388
#487	RERE	2	10	12	366.623
#488	NFATC2	2	10	12	381.5
#489	PAX7	2	9	11	532.926
#490	ZNF197	2	15	17	303.124
#491	GSC	2	7	9	259.924
#492	ETV1	1	11	12	202.146
#493	LHX9	1	12	13	256.15
#494	DMRT1	1	6	7	241.415
#495	ZIC5	1	8	9	170.987
#496	MKX	1	4	5	3.569
#497	SPIC	1	8	9	70.385
#498	HES5	1	8	9	86.435
#499	FOSB	1	9	10	117.737
#500	PGBD1	0	9	9	0