Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZFP36L2	40	0	40	0
#2	IKZF1	30	1	31	11.846
#3	TCF7	30	7	37	2498.261
#4	FOXO1	29	5	34	551.459
#5	JUND	28	3	31	172.067
#6	STAT6	28	7	35	1682.716
#7	FLI1	28	4	32	2485.956
#8	ATF3	26	9	35	1579.093
#9	HSF1	25	9	34	3343.633
#10	ENO1	25	4	29	265.569
#11	RELA	25	4	29	389.427
#12	NR4A2	25	6	31	671.818
#13	BCL6	25	11	36	4223.996
#14	MGA	24	7	31	1668.535
#15	CREM	24	4	28	299.676
#16	SPIB	24	3	27	164.674
#17	REL	24	8	32	266.027
#18	BHLHE40	24	5	29	980.598
#19	LEF1	23	7	30	275.427
#20	CEBPA	23	10	33	1162.082
#21	MAFF	23	3	26	84.93
#22	SCML1	23	9	32	2189.921
#23	ZGPAT	22	11	33	2009.156
#24	RUNX3	22	7	29	244.371
#25	EGR1	22	6	28	1209.98
#26	MAX	22	6	28	474.617
#27	CBFA2T3	22	3	25	1045.688
#28	ZXDC	22	7	29	1779.039
#29	TBX21	21	4	25	283.617
#30	ZBTB48	21	7	28	2658.843
#31	SOLH	21	8	29	579.543
#32	NFIL3	20	3	23	350.712
#33	GAS7	20	13	33	2086.09
#34	ZNF238	20	10	30	1757.184
#35	STAT1	20	8	28	446.579
#36	CUX1	20	11	31	2367.885
#37	TAF12	20	10	30	5589.207
#38	FOSB	20	8	28	1993.737
#39	JUNB	20	4	24	110.636
#40	TFEB	20	4	24	3574.871
#41	CBFA2T2	19	7	26	760.597
#42	ALS2CR8	19	7	26	999.104
#43	MYF6	19	10	29	2581.151
#44	SOX17	19	10	29	2220.223
#45	RORA	19	10	29	713.718
#46	FOXA1	18	6	24	996.544
#47	SMAD3	18	5	23	1927.727
#48	GABPB1	18	14	32	2200.867
#49	TBR1	18	7	25	1194.968
#50	FOSL2	18	4	22	162.928
#51	ARNTL	18	8	26	782.378
#52	PHTF1	18	12	30	1310.345
#53	ZEB2	18	5	23	1838.174
#54	TSC22D3	18	10	28	483.573
#55	SMAD5	18	9	27	764.898
#56	SIX5	18	9	27	1137.99
#57	BACH2	18	11	29	1004.305
#58	HHEX	17	5	22	128.951
#59	SIX2	17	11	28	1761.628
#60	LHX5	17	7	24	666.118
#61	CBFB	17	7	24	1813.172
#62	NR1D2	17	9	26	307.662
#63	TCF3	17	10	27	468.546
#64	TADA3	17	9	26	1443.961
#65	MZF1	17	11	28	824.055
#66	ZSCAN18	17	13	30	2584.103
#67	HNF4A	17	7	24	1811.409
#68	CBL	17	6	23	722.136
#69	HOPX	17	4	21	516.306
#70	MTA2	16	15	31	3461.275
#71	NFYB	16	8	24	1259.555
#72	NFYA	16	9	25	822.318
#73	HOXD13	16	12	28	3041.16
#74	GATA6	16	13	29	2091.399
#75	JUN	16	8	24	376.603
#76	ARNT	16	5	21	596.127
#77	ZFHX3	16	9	25	1446.068
#78	MYC	16	11	27	2093.798
#79	TCF4	16	3	19	417.678
#80	HMG20B	16	6	22	543.128
#81	GATA3	16	6	22	542.893
#82	AHR	15	13	28	775.638
#83	SUPT4H1	15	10	25	1599.399
#84	TP73	15	7	22	912.807
#85	SOX18	15	10	25	1207.648
#86	MEIS3P1	15	11	26	1092.068
#87	KLF6	15	8	23	1317.611
#88	NEUROD1	15	8	23	1077.817
#89	AFF1	15	11	26	1016.913
#90	ZNF140	15	7	22	1188.344
#91	SOX13	15	10	25	1031.931
#92	E2F6	15	8	23	1086.68
#93	ZSCAN2	15	10	25	1637.78
#94	GATA2	15	7	22	886.661
#95	TP53	15	9	24	597.625
#96	ZNF174	15	15	30	2485.006
#97	ATOH1	15	11	26	2057.258
#98	GLI2	15	11	26	1485.892
#99	ZNF165	15	12	27	992.204
#100	IRF8	15	3	18	181.431
#101	MAF	14	8	22	593.684
#102	ZNF175	14	10	24	942.694
#103	RXRB	14	9	23	655.696
#104	BACH1	14	7	21	586.416
#105	HOXA5	14	13	27	2156.157
#106	EGR3	14	7	21	1068.908
#107	TFAP2A	14	10	24	1720.233
#108	BTG2	14	7	21	542.057
#109	GTF2H4	14	11	25	966.349
#110	NFYC	14	6	20	7634.015
#111	NEUROG1	14	7	21	978.56
#112	SP1	14	8	22	1673.966
#113	LHX2	14	12	26	2219.274
#114	PCGF2	14	10	24	2092.644
#115	SPI1	14	9	23	1284.608
#116	E2F5	14	7	21	857.087
#117	MAFB	14	10	24	1256.339
#118	USF2	14	12	26	490.631
#119	TFAP4	14	15	29	2418.778
#120	MYCN	14	10	24	1309.313
#121	CSDA	14	14	28	526.419
#122	MSRB2	14	15	29	2640.737
#123	HOXA6	14	12	26	1527.557
#124	TBX2	13	12	25	2327.038
#125	NR1H4	13	13	26	2289.53
#126	ONECUT2	13	14	27	2603.376
#127	MEF2C	13	9	22	2226.804
#128	HOXC5	13	9	22	1217.29
#129	KLF9	13	5	18	449.681
#130	HOXA11	13	12	25	1114.704
#131	C11orf9	13	11	24	1178.233
#132	GTF2I	13	8	21	438.879
#133	NKX3-2	13	10	23	1489.704
#134	NR3C2	13	11	24	1251.99
#135	C2orf3	13	14	27	2197.958
#136	CITED2	13	11	24	771.215
#137	HINFP	13	13	26	1636.114
#138	SREBF1	13	10	23	867.637
#139	MEF2A	13	8	21	718.436
#140	NFX1	13	6	19	632.106
#141	WT1	13	10	23	1245.793
#142	IKZF3	13	13	26	911.506
#143	ZNF236	13	12	25	2649.248
#144	HNF1A	13	10	23	1290.348
#145	RUNX2	13	8	21	656.302
#146	E2F1	13	10	23	1188.57
#147	FOXO4	13	11	24	1243.591
#148	HOXA4	13	8	21	833.848
#149	ZNF323	13	10	23	2097.942
#150	NKX2-5	13	12	25	1775.934
#151	GCM1	13	9	22	2600.038
#152	SOX5	12	9	21	1191.535
#153	NR4A3	12	8	20	226.57
#154	ZNF444	12	12	24	1636.544
#155	SOX30	12	12	24	1716.166
#156	TFEC	12	13	25	1345.022
#157	RERE	12	14	26	1301.746
#158	ZNF639	12	10	22	1105.481
#159	BRD8	12	15	27	1773.196
#160	EHF	12	14	26	1397.642
#161	LHX6	12	14	26	1903.941
#162	ZEB1	12	14	26	2732.238
#163	PLSCR1	12	9	21	1484.218
#164	GATA1	12	10	22	1470.086
#165	PPARA	12	11	23	1433.096
#166	NPAS1	12	13	25	1458.37
#167	HOXC10	12	13	25	1450.733
#168	ALX4	12	8	20	1126.863
#169	ISL1	12	9	21	1226.744
#170	PRRX2	12	10	22	2337.323
#171	ZNF643	12	13	25	1874.707
#172	RORC	12	12	24	1750.511
#173	HOXA1	12	10	22	1788.986
#174	CDKN2A	12	12	24	1822.024
#175	PRDM1	12	11	23	863.268
#176	ZNF277	12	12	24	1913.87
#177	SOX10	12	8	20	827.613
#178	RB1	12	12	24	1521.027
#179	CRX	12	9	21	1104.668
#180	TCF15	12	7	19	986.472
#181	NR2C2	12	4	16	449.436
#182	HMX1	12	7	19	1031.73
#183	LMO4	12	10	22	1432.4
#184	HOXC4	12	11	23	335.633
#185	HOXB9	12	8	20	1128.373
#186	THRA	11	10	21	1131.929
#187	SCAND2	11	13	24	1403.379
#188	NR4A1	11	10	21	227.084
#189	MEF2D	11	13	24	1149.177
#190	RARA	11	11	22	931.126
#191	MAFG	11	13	24	1285.817
#192	FOXI1	11	11	22	1337.669
#193	NFE2	11	7	18	827.595
#194	POU2F2	11	10	21	1884.445
#195	NFIC	11	13	24	1433.45
#196	TP63	11	10	21	1730.976
#197	NR6A1	11	16	27	1797.102
#198	PAX4	11	9	20	902.417
#199	TCF12	11	9	20	1271.629
#200	PRDM2	11	14	25	1138.124
#201	POU3F4	11	8	19	1486.23
#202	BCL3	11	7	18	682.718
#203	GABPA	11	13	24	2190.477
#204	ALX3	11	10	21	2063.002
#205	MEIS1	11	11	22	1125.403
#206	KLF1	11	10	21	1651.793
#207	E2F3	11	10	21	1357.647
#208	PAX5	11	13	24	1536.08
#209	HOXA7	11	14	25	2088.099
#210	MLL	11	12	23	540.419
#211	ZNF135	11	12	23	1585.151
#212	KLF4	11	12	23	689.447
#213	SOX4	11	12	23	1386.255
#214	NR2E1	11	9	20	1106.436
#215	MYOD1	11	7	18	770.219
#216	YY1	11	11	22	1211.68
#217	PROX1	11	7	18	631.044
#218	ZNF132	11	14	25	1475.741
#219	MEOX2	11	13	24	1423.789
#220	FOS	11	8	19	628.101
#221	TBX5	11	12	23	2154.665
#222	POU6F1	11	10	21	1803.661
#223	HES1	11	11	22	1191.705
#224	FOXC1	11	9	20	624.234
#225	MYCL1	11	10	21	1412.471
#226	HOXB8	11	11	22	1245.482
#227	ESR2	10	10	20	569.753
#228	AR	10	11	21	1187.296
#229	TAF1B	10	11	21	1743.384
#230	PAX8	10	5	15	453.961
#231	BNC1	10	13	23	1388.129
#232	IRF5	10	9	19	897.822
#233	TRIM25	10	12	22	1840.077
#234	EGR2	10	16	26	1227.546
#235	FOXE3	10	8	18	766.642
#236	LHX1	10	9	19	629.201
#237	TBX6	10	12	22	1331.528
#238	ERF	10	7	17	687.927
#239	MLXIPL	10	12	22	1374.167
#240	TBX10	10	7	17	561.558
#241	IRX5	10	10	20	1200.825
#242	EPAS1	10	13	23	978.214
#243	PBX2	10	13	23	1587.865
#244	T	10	11	21	1162.713
#245	ZNF268	10	9	19	1266.307
#246	KLF11	10	9	19	1744.6
#247	RFXAP	10	13	23	1315.095
#248	NFIX	10	13	23	1634.815
#249	AEBP1	10	9	19	590.874
#250	TAL1	10	11	21	1525.997
#251	ZFP36L1	10	8	18	400.4
#252	EMX1	10	13	23	1504.433
#253	MITF	10	13	23	1086.496
#254	FOXD2	10	11	21	4958.92
#255	PAX3	10	12	22	1221.074
#256	CLOCK	10	8	18	775.14
#257	FOXM1	10	9	19	827.758
#258	PGR	10	9	19	1764.545
#259	KLF10	10	8	18	179.165
#260	HIF3A	10	11	21	1164.978
#261	ARNT2	9	13	22	1354.547
#262	POU4F1	9	8	17	959.572
#263	CREBZF	9	7	16	371.521
#264	FOXH1	9	12	21	1231.79
#265	ERG	9	9	18	904.183
#266	ZNF131	9	11	20	359.672
#267	ZNF187	9	6	15	1122.368
#268	ZNF446	9	12	21	1205.313
#269	SRF	9	12	21	893.751
#270	ZNF80	9	11	20	1234.159
#271	CREBBP	9	11	20	390.889
#272	HOXD3	9	9	18	841.969
#273	NR1I2	9	14	23	3236.143
#274	HMGA1	9	13	22	604.677
#275	DMRT1	9	13	22	1493.475
#276	ARNTL2	9	17	26	1066.497
#277	HOXB2	9	11	20	1683.098
#278	ZNF193	9	9	18	1545.352
#279	POU6F2	9	12	21	1561.488
#280	RORB	9	9	18	958.001
#281	MMP14	9	11	20	1687.593
#282	SIX1	9	9	18	1580.653
#283	VENTX	9	10	19	925.016
#284	ZNF81	9	7	16	756.091
#285	TFDP2	9	9	18	721.049
#286	FOSL1	9	8	17	2117.455
#287	RARG	9	16	25	1999.279
#288	HOXA10	9	15	24	1468.726
#289	HOXA9	9	13	22	827.461
#290	ZNF287	9	11	20	910.345
#291	MSX2	9	19	28	1889.504
#292	GSC2	9	9	18	762.54
#293	SOX9	9	6	15	630.597
#294	FOXO3	9	14	23	723.138
#295	ZIC3	9	12	21	1149.397
#296	TSHZ2	9	10	19	1197.983
#297	TEAD4	9	12	21	1053.373
#298	ETS2	9	13	22	1252.404
#299	PKNOX2	9	15	24	1583.691
#300	PPARG	9	11	20	813.202
#301	ZNF219	8	9	17	708.13
#302	TAF4	8	9	17	458.54
#303	NR2C1	8	14	22	888.123
#304	CEBPE	8	12	20	1301.175
#305	CSRNP3	8	13	21	795.744
#306	NR2E3	8	12	20	2149.892
#307	ZNF167	8	14	22	1804.081
#308	HLF	8	13	21	1014.643
#309	KLF12	8	16	24	896.653
#310	STRN3	8	17	25	1576.9
#311	ZHX3	8	9	17	787.898
#312	HOXB6	8	9	17	442.389
#313	VTN	8	8	16	570.815
#314	TBX4	8	10	18	1010.615
#315	HOXA3	8	9	17	525.25
#316	RAX	8	15	23	1405.342
#317	ZFP37	8	7	15	675.206
#318	NR2F2	8	10	18	780.012
#319	FOXF1	8	8	16	734.843
#320	NR5A1	8	15	23	1190.528
#321	MYBL2	8	16	24	1236.163
#322	FOXB1	8	8	16	974.07
#323	SIM2	8	11	19	1580.098
#324	HAND1	8	8	16	888.845
#325	FOXD3	8	9	17	707.793
#326	HNF4G	8	13	21	1346.551
#327	ESRRA	8	6	14	569.561
#328	TADA2A	8	7	15	346.574
#329	STAT2	8	9	17	909.839
#330	FOXJ1	8	9	17	460.048
#331	GBX2	8	16	24	1632.703
#332	TBX3	8	11	19	1535.44
#333	HOXD1	8	11	19	970.826
#334	HEY2	8	9	17	694.17
#335	PAX7	8	9	17	860.674
#336	PBX1	8	10	18	733.729
#337	ELF5	8	10	18	869.745
#338	TFAP2C	8	8	16	714.286
#339	MEIS2	8	12	20	938.738
#340	TCF7L2	8	11	19	473.611
#341	HOXD9	8	12	20	856.74
#342	SCRT1	8	8	16	910.709
#343	MYT1L	8	10	18	780.523
#344	ZNF134	7	17	24	1168.441
#345	ELK4	7	14	21	819.524
#346	TEF	7	11	18	641.142
#347	MSC	7	14	21	1269.566
#348	BHLHE41	7	9	16	732.981
#349	SOX2	7	15	22	1478.989
#350	ZNF155	7	13	20	690.93
#351	PITX2	7	12	19	996.781
#352	POU3F2	7	11	18	411.292
#353	ETV5	7	11	18	621.948
#354	NFAT5	7	14	21	752.929
#355	DLX6	7	15	22	856.01
#356	NFATC4	7	13	20	1163.631
#357	TAF13	7	10	17	688.669
#358	TRIM29	7	7	14	490.861
#359	HOXC8	7	17	24	1579.208
#360	RARB	7	13	20	1019.667
#361	TBX19	7	8	15	753.552
#362	KLF15	7	18	25	1250.046
#363	HOXD11	7	10	17	837.297
#364	NR5A2	7	12	19	887.693
#365	POU3F3	7	15	22	1539.318
#366	MECOM	7	17	24	1329.235
#367	TEAD3	7	13	20	1092.993
#368	ETV2	7	19	26	1368.516
#369	RBPJL	7	14	21	1199.05
#370	HAND2	7	12	19	1106.672
#371	FOXE1	7	12	19	1174.208
#372	NANOG	7	10	17	323.99
#373	WNT5A	7	15	22	1158.174
#374	HOXB7	7	14	21	900.336
#375	FOXA2	7	8	15	456.516
#376	DLX4	7	10	17	957.121
#377	KDM5B	7	12	19	1462.554
#378	SNAPC5	7	9	16	560.361
#379	TCFL5	7	10	17	620.23
#380	FOXD1	7	14	21	1664.042
#381	NR2F6	7	17	24	1123.425
#382	SOX21	7	11	18	979.616
#383	POU3F1	7	14	21	5809.52
#384	POU2F3	7	13	20	711.534
#385	ETV1	7	18	25	1805.037
#386	IRF4	7	13	20	1132.068
#387	HIRA	7	13	20	870.616
#388	ELF4	7	17	24	1210.632
#389	ASCL1	7	13	20	778.626
#390	ZNF202	7	7	14	574.589
#391	HOXC13	6	11	17	781.913
#392	VDR	6	14	20	705.989
#393	ELK3	6	16	22	1010.492
#394	ESRRB	6	10	16	404.744
#395	BLZF1	6	15	21	1115.87
#396	ONECUT1	6	14	20	1070.868
#397	OLIG2	6	12	18	1124.022
#398	SALL1	6	13	19	1216.294
#399	ETV7	6	11	17	393.537
#400	FOXC2	6	10	16	520.388
#401	NKX6-1	6	11	17	598.437
#402	NR1I3	6	12	18	673.735
#403	PPARD	6	14	20	986.846
#404	NKX2-1	6	12	18	1033.629
#405	HOXA2	6	10	16	968.555
#406	MYT1	6	12	18	727.846
#407	ESR1	6	14	20	791.43
#408	KLF5	6	9	15	1057.893
#409	IRX4	6	10	16	641.248
#410	TFAP2B	6	14	20	735.992
#411	EN2	6	17	23	928.991
#412	SIM1	6	15	21	1039.901
#413	SIX3	6	9	15	1203.828
#414	HIC1	6	13	19	1441.669
#415	HESX1	6	12	18	907.813
#416	ELF3	6	12	18	1096.533
#417	REST	6	9	15	430.977
#418	CUX2	6	9	15	653.957
#419	ZKSCAN4	6	16	22	1314.309
#420	SLC26A3	6	12	18	698.58
#421	NPAT	6	11	17	1367.335
#422	SMAD6	6	11	17	639.453
#423	BARX1	6	14	20	942.296
#424	BATF3	6	14	20	1108.38
#425	MAFK	6	11	17	675.584
#426	PITX1	5	10	15	377.293
#427	NFKB2	5	11	16	616.28
#428	HOXB3	5	12	17	662.864
#429	RUNX1T1	5	12	17	530.828
#430	MEOX1	5	9	14	542.577
#431	HNF1B	5	13	18	390.559
#432	CTBP1	5	13	18	729.058
#433	DBP	5	11	16	613.121
#434	PKNOX1	5	11	16	683.901
#435	NR2F1	5	8	13	566.605
#436	SNAI2	5	11	16	803.954
#437	MNX1	5	14	19	734.879
#438	TSC22D2	5	8	13	413.068
#439	PTH	5	13	18	768.655
#440	ZNF41	5	9	14	267.35
#441	MLLT10	5	13	18	523.7
#442	TLX3	5	15	20	503.524
#443	NRL	5	13	18	698.972
#444	RUNX1	5	15	20	622.175
#445	ELK1	5	10	15	1064.16
#446	ZNF117	5	10	15	541.651
#447	E2F8	5	14	19	738.723
#448	ATF6B	5	18	23	984.641
#449	GATA4	5	14	19	805.245
#450	SPDEF	5	19	24	1297.02
#451	POU1F1	5	13	18	886.744
#452	SRY	5	9	14	379.86
#453	VSX1	5	15	20	630.855
#454	TLX2	5	9	14	648.561
#455	EGR4	5	13	18	497.785
#456	PPBPL2	5	10	15	421.313
#457	CEBPD	5	10	15	710.144
#458	BUD31	5	11	16	599.943
#459	TBX1	5	15	20	653.991
#460	HOXB1	5	13	18	718.963
#461	CREB5	4	11	15	432.826
#462	NFATC1	4	14	18	571.467
#463	MYF5	4	14	18	498.464
#464	ATF6	4	16	20	795.694
#465	OVOL1	4	10	14	560.551
#466	NKX2-8	4	11	15	487.264
#467	DLX2	4	11	15	524.384
#468	ZNF154	4	10	14	387.642
#469	TEAD1	4	11	15	826.273
#470	ZNF3	4	11	15	379.143
#471	HOXD4	4	15	19	624.702
#472	SOX11	4	15	19	1072.795
#473	KDM5A	4	15	19	719.371
#474	NFIB	4	14	18	1298.309
#475	E2F2	4	12	16	554.968
#476	ESRRG	4	13	17	821.199
#477	FOXP3	4	11	15	475.206
#478	TCF21	4	16	20	1215.14
#479	SATB2	4	16	20	722.663
#480	EN1	3	12	15	165.476
#481	PHOX2A	3	12	15	271.987
#482	MSX1	3	13	16	802.564
#483	PDX1	3	14	17	383.042
#484	ZFPM2	3	10	13	468.375
#485	FOXG1	3	14	17	317.952
#486	LZTS1	3	13	16	298.122
#487	ZNF157	3	15	18	763.358
#488	POU4F3	3	11	14	532.595
#489	TFDP3	2	14	16	396.461
#490	NR0B1	2	12	14	401.997
#491	MXD1	2	16	18	256.943
#492	ATF5	2	14	16	277.462
#493	FOXL2	2	15	17	273.029
#494	TWIST1	2	18	20	303.589
#495	RCAN1	2	12	14	260.476
#496	ETV4	2	9	11	171.191
#497	RXRA	2	15	17	131.098
#498	NPAS2	2	15	17	608.538
#499	SMAD1	1	16	17	144.491
#500	ETV3	1	20	21	107.625