Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ELF4	45	4	49	558.302
#2	MTA3	42	6	48	666.825
#3	SOX6	39	5	44	487.337
#4	MYNN	38	3	41	519.88
#5	CSRNP3	37	10	47	3666.601
#6	ELK3	36	7	43	1599.238
#7	CNOT8	36	3	39	90.882
#8	TCF3	34	3	37	1106.058
#9	SMAD4	34	0	34	0
#10	RFXANK	34	5	39	571.249
#11	ARNT2	34	9	43	2779.108
#12	ZNF639	34	3	37	195.991
#13	SOX4	34	13	47	2263.553
#14	KLF12	34	7	41	1028.027
#15	SOX8	32	5	37	793.01
#16	TGIF1	32	11	43	2753.236
#17	ZNF217	32	8	40	1091.566
#18	E2F7	31	6	37	954.66
#19	ETV1	30	9	39	2900.475
#20	OLIG2	30	4	34	606.585
#21	CSDA	29	10	39	1613.277
#22	ZNF238	29	7	36	1662.087
#23	SOX2	29	8	37	1415.258
#24	MYT1	29	8	37	1976.977
#25	TSHZ1	28	8	36	634.001
#26	JUNB	28	0	28	0
#27	ZNF277	28	5	33	2663.595
#28	ZKSCAN5	28	5	33	325.969
#29	HDAC2	28	8	36	838.788
#30	HSF2	28	10	38	1686.39
#31	PCGF6	28	4	32	138.274
#32	ZNF131	27	5	32	634.323
#33	PAX6	26	17	43	3527.093
#34	THRA	26	7	33	1056.848
#35	ATF1	26	7	33	227.479
#36	MSRB2	26	8	34	683.85
#37	KDM5A	26	7	33	859.391
#38	ZNF92	25	6	31	670.256
#39	YEATS4	25	4	29	110.585
#40	ZNF45	25	7	32	295.47
#41	MSX1	25	9	34	2027.351
#42	HNRNPAB	25	9	34	1247.666
#43	TRPS1	25	11	36	3099.446
#44	FOSL2	25	4	29	505.247
#45	ZNF134	24	4	28	489.672
#46	STAT3	24	4	28	351.886
#47	TCF12	24	7	31	722.935
#48	SALL1	24	14	38	3576.138
#49	BCL3	24	13	37	1630.799
#50	GABPA	24	11	35	1123.468
#51	ZFHX4	24	8	32	1310.19
#52	SMAD2	24	4	28	2695.308
#53	RUNX2	24	9	33	2633.481
#54	C1orf85	24	7	31	1282.55
#55	FOXN2	23	7	30	478.289
#56	RUNX1	23	7	30	1535.287
#57	LEF1	23	9	32	2038.986
#58	KCNH8	23	16	39	1799.155
#59	GLIS3	23	15	38	3620.583
#60	SNAI2	23	18	41	4370.763
#61	TFE3	23	7	30	369.919
#62	MYCN	23	18	41	4984.734
#63	PURA	23	9	32	1541.23
#64	NR2C2	23	6	29	242.472
#65	SOX11	23	11	34	2137.319
#66	MEF2C	22	9	31	1887.554
#67	ZSCAN21	22	10	32	1585.292
#68	TRIM22	22	6	28	1078.537
#69	PRDM2	22	14	36	1341.448
#70	YBX1	22	12	34	1129.537
#71	NR2E1	22	15	37	1629.858
#72	POU3F2	22	11	33	6592.923
#73	TEF	21	8	29	377.079
#74	ZSCAN16	21	8	29	487.104
#75	SP4	21	7	28	459.913
#76	CBFA2T3	21	13	34	4398.594
#77	HMG20B	21	7	28	2055.33
#78	ZNF367	21	12	33	1483.119
#79	HMG20A	21	12	33	1744.607
#80	CEBPB	21	9	30	1467.093
#81	TCF7L1	21	16	37	2196.105
#82	HIF1A	20	13	33	2033.225
#83	ZEB1	20	9	29	928.059
#84	FBXW7	20	13	33	1388.91
#85	STAT6	20	10	30	1416.414
#86	ZNF3	20	9	29	385.878
#87	ZNF148	20	10	30	1449.945
#88	GATA6	20	9	29	1829.613
#89	TSC22D1	19	9	28	2158.655
#90	ZNF33A	19	12	31	1523.883
#91	RELA	19	8	27	908.649
#92	TCF19	19	5	24	995.581
#93	MEOX2	19	19	38	1883.724
#94	HOXD4	19	8	27	1114.059
#95	SATB1	19	12	31	1309.229
#96	FOXM1	19	3	22	197.77
#97	GLI2	19	13	32	3106.723
#98	ETV6	19	11	30	1199.098
#99	NOTCH1	19	13	32	818.222
#100	KLF6	18	6	24	486.58
#101	ZFHX3	18	13	31	1332.836
#102	ASCL1	18	10	28	942.215
#103	E2F3	18	12	30	802.988
#104	HES6	18	9	27	491.578
#105	DMTF1	18	15	33	3791.194
#106	NFYA	18	12	30	2031.243
#107	PLSCR1	18	12	30	1030.311
#108	BRD8	18	9	27	2336.317
#109	TCF25	18	11	29	1164.667
#110	NFYB	18	9	27	360.006
#111	DLX6	18	3	21	1287.09
#112	SMAD5	18	12	30	1191.044
#113	TFAM	18	16	34	1511.724
#114	STAT4	18	5	23	988.488
#115	THRB	17	14	31	1712.222
#116	C2orf3	17	11	28	1181.741
#117	ZNF24	17	5	22	500.363
#118	SALL2	17	11	28	1485.051
#119	TEAD2	17	12	29	1040.4
#120	STRN3	17	10	27	1377.091
#121	GLI3	17	17	34	2384.902
#122	TEAD4	17	12	29	1817.121
#123	SOX9	17	14	31	1478.396
#124	CREB1	17	9	26	822.325
#125	VDR	17	13	30	1927.053
#126	ZEB2	17	5	22	591.875
#127	HCLS1	17	2	19	114.654
#128	HMGB2	17	10	27	562.96
#129	LMO4	17	13	30	2032.475
#130	KDM5B	17	14	31	3386.473
#131	ADNP2	17	10	27	823.881
#132	ZNF167	17	14	31	998.814
#133	SMAD1	17	14	31	1054.806
#134	CREBL2	17	14	31	1809.141
#135	TFCP2	17	7	24	168.913
#136	HDAC1	17	14	31	799.823
#137	CUX1	17	4	21	261.379
#138	BACH1	16	12	28	857.562
#139	ZNF138	16	11	27	731.687
#140	JUN	16	11	27	2014.701
#141	ZNF140	16	7	23	327.062
#142	MYC	16	11	27	2982.687
#143	SRF	16	8	24	1501.347
#144	BTG2	16	5	21	502.648
#145	PHTF1	16	16	32	628.789
#146	TFAP2C	16	10	26	4182.959
#147	E2F8	16	8	24	2328.086
#148	PURB	16	12	28	1305.578
#149	ATF3	16	6	22	117.274
#150	ZNF232	16	13	29	2799.698
#151	CSRNP1	16	3	19	1061.932
#152	ZNF281	16	11	27	1093.263
#153	GCFC1	16	10	26	1304.02
#154	HOPX	16	14	30	1313.757
#155	PEG3	16	19	35	4156.244
#156	MZF1	16	13	29	2179.52
#157	E2F5	16	12	28	762.995
#158	BACH2	15	16	31	1290.59
#159	SMAD3	15	10	25	1404.142
#160	GATAD2B	15	10	25	1616.205
#161	CNOT7	15	12	27	671.086
#162	CNBP	15	9	24	497.686
#163	SIX5	15	12	27	2521.783
#164	CREBZF	15	9	24	607.546
#165	ARNTL	15	10	25	1520.486
#166	ONECUT2	15	10	25	960.733
#167	MTA1	15	8	23	625.779
#168	HEYL	15	10	25	1186.555
#169	GATAD1	15	10	25	1380.448
#170	CREB3L2	15	10	25	1310.055
#171	VAV1	15	5	20	385.223
#172	ZFP37	14	14	28	767.822
#173	MEIS1	14	12	26	1496.729
#174	PTTG1	14	2	16	481.424
#175	IKZF4	14	15	29	3287.905
#176	MKX	14	14	28	4149.636
#177	LCOR	14	14	28	1039.13
#178	TAF10	14	11	25	745.133
#179	IKZF1	14	4	18	212.95
#180	ADNP	14	15	29	1251.366
#181	POU6F1	14	6	20	594.357
#182	MAFF	14	8	22	390.879
#183	FOS	14	4	18	355.392
#184	ZHX1	14	15	29	1387.552
#185	FLI1	14	10	24	1579.424
#186	SIX2	14	3	17	215.334
#187	SREBF1	14	12	26	548.584
#188	TEAD1	14	10	24	1430.676
#189	CREM	14	10	24	1119.795
#190	POU4F1	14	12	26	1283.945
#191	NR2C1	14	14	28	1759.664
#192	MEF2A	13	8	21	1003.197
#193	LHX8	13	5	18	717.145
#194	HOXA5	13	6	19	1512.034
#195	PBX1	13	14	27	871.763
#196	HEY1	13	13	26	1006.034
#197	MAFB	13	10	23	986.487
#198	NR3C2	13	14	27	932.951
#199	TRIM28	13	12	25	1844.739
#200	ZNF93	13	11	24	890.047
#201	ZNF236	13	11	24	2189.038
#202	ZNF70	13	13	26	1473.837
#203	HOXC9	13	6	19	739.093
#204	HOXA10	13	9	22	1319.034
#205	BATF3	13	11	24	1416.386
#206	STAT2	13	7	20	847.25
#207	NFATC2	13	12	25	1511.841
#208	PGBD1	13	16	29	742.157
#209	UHRF1	13	12	25	528.485
#210	HOXA7	12	15	27	1586.594
#211	MEOX1	12	3	15	807.847
#212	NFIC	12	24	36	2921.863
#213	BHLHE40	12	13	25	1770.43
#214	ARID4A	12	16	28	1363.451
#215	HES1	12	9	21	1184.831
#216	FOSB	12	4	16	42.144
#217	SIX4	12	11	23	972.961
#218	ZNF117	12	9	21	949.161
#219	NPAT	12	16	28	740.379
#220	POU2F1	12	13	25	874.7
#221	TSC22D2	12	14	26	2307.943
#222	ELF2	12	9	21	1873.2
#223	NFATC1	12	21	33	1588.06
#224	AFF1	12	9	21	681.505
#225	C5orf41	12	9	21	1249.226
#226	ZSCAN18	12	18	30	4676.234
#227	ZRANB2	12	7	19	574.682
#228	RORA	12	17	29	1204.152
#229	NFXL1	12	14	26	1308.403
#230	FOXC2	12	12	24	1492.509
#231	TBX2	12	12	24	875.049
#232	ZNF165	12	7	19	1334.945
#233	ETS1	12	18	30	2116.839
#234	EGR1	12	8	20	446.318
#235	NFIA	11	15	26	876.895
#236	RCOR1	11	13	24	2009.511
#237	CEBPA	11	8	19	630.352
#238	LASS2	11	14	25	668.92
#239	KLF7	11	12	23	1284.753
#240	MGA	11	7	18	669.831
#241	ZNF83	11	18	29	1434.252
#242	HOXA9	11	9	20	1110.219
#243	EGR3	11	10	21	1435.69
#244	GATAD2A	11	11	22	1451.427
#245	RFX3	11	17	28	2685.844
#246	MYT1L	11	16	27	1103.037
#247	RARA	11	12	23	2898.46
#248	EBF1	11	17	28	2045.312
#249	HES5	11	14	25	1532.302
#250	DMRT2	11	12	23	3825.435
#251	GAS7	11	21	32	4091.04
#252	FUBP1	11	14	25	720.565
#253	TFEC	11	7	18	911.72
#254	EGR2	11	8	19	319.354
#255	ZSCAN29	10	9	19	956.743
#256	ST18	10	8	18	1304.59
#257	CEBPD	10	12	22	873.583
#258	HLF	10	13	23	563.022
#259	STAT1	10	4	14	125.382
#260	FOXG1	10	17	27	938.352
#261	FOXC1	10	15	25	754.273
#262	TCF7L2	10	16	26	844.064
#263	NR1D2	10	14	24	922.161
#264	KLF5	10	17	27	1522.719
#265	NFIL3	10	15	25	848.476
#266	ZFP36L2	10	21	31	1299.842
#267	ETV5	10	13	23	1218.636
#268	BCL6	10	18	28	1164.66
#269	NR2F1	10	15	25	1737.398
#270	RBPJ	10	13	23	1600.849
#271	PCGF2	10	13	23	1280.672
#272	KLF3	10	16	26	1347.872
#273	ZBTB38	10	18	28	1068.942
#274	CTNNB1	10	19	29	693.501
#275	SPEN	10	10	20	1738.508
#276	TBX15	10	14	24	997.645
#277	AHCTF1	10	19	29	1156.329
#278	HMGA1	10	9	19	819.778
#279	CBFB	10	18	28	2123.479
#280	SP3	10	17	27	2270.328
#281	TFEB	10	15	25	1552.189
#282	MEF2D	10	15	25	1305.31
#283	SCAND1	10	9	19	1025.908
#284	BTAF1	10	9	19	1159.948
#285	RUNX3	10	11	21	1880.704
#286	TBX3	10	10	20	489.755
#287	RARB	9	16	25	2701.546
#288	TWIST2	9	12	21	2994.204
#289	NFAT5	9	9	18	573.852
#290	TWIST1	9	20	29	4134.581
#291	TSHZ3	9	21	30	1644.493
#292	NR0B1	9	14	23	1610.02
#293	IRF8	9	3	12	69.065
#294	NFE2L2	9	11	20	962.309
#295	ZXDA	9	20	29	969.543
#296	HOXC10	9	8	17	1611.992
#297	NFATC4	9	12	21	1601.339
#298	FOXP1	9	20	29	1074.859
#299	EGR4	9	13	22	3179.136
#300	ETS2	9	14	23	678.679
#301	TAF7	9	12	21	277.376
#302	TARDBP	9	15	24	1901.599
#303	ESRRG	9	18	27	891.689
#304	ZHX3	9	18	27	1730.289
#305	HOXB6	9	9	18	488.774
#306	KLF10	9	13	22	1608.229
#307	IRX2	9	15	24	1779.242
#308	TCF4	9	17	26	719.903
#309	HOXA1	9	10	19	1330.385
#310	DLX1	9	17	26	1654.138
#311	RFX5	9	18	27	1489.961
#312	ZNF397	9	15	24	1167.697
#313	FOXN3	9	13	22	1384.991
#314	NR4A1	9	6	15	572.959
#315	TRIM25	8	16	24	1463.977
#316	NR4A3	8	12	20	480.501
#317	FOXD1	8	15	23	594.053
#318	NANOG	8	18	26	1303.8
#319	DDIT3	8	21	29	3550.176
#320	NFIB	8	18	26	1575.295
#321	HOXD8	8	13	21	789.608
#322	JUND	8	12	20	837.038
#323	CREB5	8	16	24	397.285
#324	TFDP1	8	19	27	1124.056
#325	CTBP1	8	22	30	2076.575
#326	FOXQ1	8	12	20	987.959
#327	TGIF2	8	18	26	1481.823
#328	IRF7	8	5	13	159.959
#329	YY1	8	12	20	744.513
#330	ZNF175	8	7	15	478.693
#331	MLLT10	8	10	18	975.831
#332	ERG	8	13	21	1553.954
#333	PA2G4	8	13	21	483.948
#334	HOXD3	8	16	24	747.026
#335	VAX2	8	13	21	894.29
#336	SIX3	8	10	18	2232.494
#337	SIM1	8	8	16	695.438
#338	RFXAP	8	13	21	578.037
#339	HOXD11	8	9	17	1228.695
#340	ZNF268	8	6	14	221.756
#341	HHEX	8	6	14	196.938
#342	SATB2	8	16	24	453.177
#343	TCFL5	8	16	24	983.818
#344	XBP1	8	17	25	515.607
#345	MAF	8	18	26	1519.431
#346	HNF4G	8	16	24	411.131
#347	TAF4	8	16	24	1140.687
#348	TULP4	8	18	26	915.934
#349	TSHZ2	8	20	28	1989.382
#350	PRRX1	7	15	22	1040.545
#351	FOXP2	7	14	21	571.357
#352	CREB3	7	14	21	1557.855
#353	PLAG1	7	18	25	1719.665
#354	RERE	7	15	22	1538.418
#355	ZNF91	7	22	29	1610.429
#356	CSRNP2	7	14	21	2121.585
#357	HOXB2	7	11	18	397.677
#358	MLL	7	14	21	788.942
#359	NFX1	7	14	21	1253.054
#360	HOXB7	7	9	16	376.504
#361	NFE2L3	7	14	21	1040.724
#362	TAF4B	7	14	21	538.001
#363	TSC22D4	7	14	21	650.672
#364	HOXD13	7	9	16	1081.111
#365	AR	7	22	29	1384.417
#366	NFIX	7	13	20	1051.275
#367	NEUROD1	7	18	25	2502.638
#368	TSC22D3	7	13	20	979.078
#369	ZKSCAN1	7	12	19	404.286
#370	FOXF2	7	11	18	621.171
#371	BUD31	7	10	17	148.79
#372	BHLHE41	7	20	27	1005.309
#373	ZNF256	7	11	18	675.963
#374	C11orf9	7	10	17	456.513
#375	KLF15	7	17	24	2139.917
#376	BCL11B	7	15	22	646.034
#377	ELF1	6	11	17	685.688
#378	ZHX2	6	15	21	927.776
#379	ZNF207	6	22	28	791.258
#380	PRDM1	6	13	19	261.444
#381	LASS6	6	14	20	1508.756
#382	NR2F6	6	17	23	257.773
#383	EPAS1	6	19	25	1540.783
#384	HMGB1	6	18	24	954.144
#385	IRF9	6	12	18	1011.336
#386	IRF2	6	15	21	598.591
#387	FOXO1	6	14	20	1023.909
#388	SOX5	6	17	23	1433.472
#389	FOXO6	6	17	23	876.735
#390	MECOM	6	15	21	541.855
#391	WNT5A	6	20	26	1752.361
#392	LHX9	6	20	26	1368.993
#393	FOXO3	6	12	18	1250.342
#394	NFATC3	6	18	24	471.318
#395	KLF4	6	11	17	651.989
#396	HOXA3	6	11	17	589.943
#397	ATF7	6	15	21	458.314
#398	AEBP1	6	19	25	1111.777
#399	BATF2	6	9	15	350.481
#400	ARNTL2	6	15	21	793.256
#401	ZSCAN5A	6	13	19	524.861
#402	MTF1	6	16	22	392.944
#403	OTX2	6	7	13	628.376
#404	NR5A2	5	11	16	455.321
#405	HMGA2	5	16	21	1447.027
#406	SIX6	5	13	18	406.292
#407	ZNF274	5	19	24	697.295
#408	WT1	5	10	15	982.211
#409	MXD1	5	17	22	504.419
#410	CUX2	5	13	18	1786.782
#411	FOXF1	5	13	18	755.207
#412	CBFA2T2	5	22	27	740.334
#413	TBX5	5	13	18	758.172
#414	PBX3	5	19	24	2233.613
#415	KLF9	5	20	25	923.409
#416	ENO1	5	19	24	429.926
#417	ZFP36L1	5	18	23	411.325
#418	ZC3H8	5	17	22	427.17
#419	NR2F2	5	18	23	2117.43
#420	ZXDC	5	18	23	855.516
#421	IRF1	5	13	18	252.372
#422	SOX7	5	17	22	728.956
#423	SOX1	5	20	25	1335.116
#424	NR3C1	5	12	17	341.123
#425	ZNF37A	5	14	19	598.965
#426	HNRNPK	5	10	15	668.989
#427	CLOCK	5	13	18	2327.105
#428	RCAN1	5	19	24	606.741
#429	PHF5A	5	16	21	1954.763
#430	RBCK1	5	12	17	208.508
#431	LZTS1	5	17	22	348.213
#432	MEIS3P1	5	20	25	942.87
#433	SMAD9	5	16	21	648.309
#434	PKNOX2	4	20	24	514.206
#435	PROX1	4	19	23	696.93
#436	SIX1	4	15	19	711.612
#437	HOXA2	4	12	16	292.4
#438	SOX10	4	13	17	446.284
#439	REL	4	11	15	316.75
#440	NFYC	4	11	15	229.462
#441	HIF3A	4	20	24	954.885
#442	TRERF1	4	22	26	1099.787
#443	DLX2	4	10	14	758.74
#444	L3MBTL4	4	18	22	602.385
#445	KLF11	4	16	20	639.161
#446	ATF6	4	16	20	462.658
#447	RB1	4	11	15	286.957
#448	AFF4	4	17	21	517.136
#449	ZIC2	4	24	28	1221.822
#450	TFAP2B	4	13	17	430.03
#451	GLIS2	4	14	18	474.459
#452	SLC30A9	4	12	16	715.438
#453	HOXD10	4	6	10	172.314
#454	ARX	3	18	21	934.617
#455	ATF5	3	24	27	1732.427
#456	TFCP2L1	3	17	20	321.926
#457	FOXD3	3	13	16	1547.439
#458	ELK1	3	13	16	754.335
#459	ZFPM2	3	21	24	404.418
#460	HIRA	3	13	16	340.011
#461	KLF2	3	10	13	688.629
#462	HEY2	3	15	18	854.586
#463	HOXB3	3	19	22	486.227
#464	CITED2	3	16	19	510.178
#465	SMAD6	3	15	18	222.614
#466	SCML1	3	18	21	503.166
#467	FOXK1	3	21	24	825.099
#468	GRHL3	3	13	16	403.795
#469	RORB	3	18	21	230.171
#470	TFDP2	3	23	26	376.407
#471	TFAP2A	3	21	24	971.875
#472	MAFK	3	16	19	295.485
#473	RUNX1T1	3	21	24	620.934
#474	CITED1	3	23	26	543.65
#475	ZFP90	2	19	21	262.811
#476	IRX3	2	21	23	315.237
#477	GTF2H2	2	17	19	254.694
#478	EN1	2	16	18	262.185
#479	PAX3	2	19	21	235.309
#480	HMBOX1	2	19	21	558.716
#481	SIN3A	2	16	18	939.156
#482	IRX1	2	24	26	1529.452
#483	LHX2	2	24	26	308.618
#484	MITF	2	23	25	595.358
#485	ZIC1	2	30	32	526.027
#486	NPAS2	2	14	16	715.283
#487	GTF2H4	2	9	11	115.391
#488	TP53	2	14	16	272.192
#489	ZNF135	1	16	17	402.412
#490	MEIS2	1	20	21	82.76
#491	ZNF323	1	20	21	106.239
#492	NR1H4	1	7	8	8.562
#493	SCAND3	1	17	18	29.695
#494	IRF5	1	10	11	58.448
#495	TAL1	1	21	22	803.155
#496	AHR	1	22	23	224.186
#497	SOX13	1	14	15	134.547
#498	NR4A2	0	12	12	0
#499	CBL	0	12	12	0
#500	CDKN2A	0	29	29	0