Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TCF4	54	4	58	1286.11
#2	NFYC	49	3	52	3582.056
#3	TCF21	47	5	52	215.444
#4	PTTG1	47	5	52	300.934
#5	ETS2	46	6	52	977.457
#6	ERG	45	2	47	45.606
#7	E2F6	44	4	48	5777.226
#8	TFCP2	43	2	45	8141.235
#9	EPAS1	43	6	49	1268.882
#10	ATF1	40	8	48	2790.066
#11	ENO1	37	6	43	1509.933
#12	HOPX	36	6	42	650.799
#13	ZHX2	34	13	47	2222.803
#14	BTG2	34	6	40	845.513
#15	RUNX1	33	11	44	1255.875
#16	NR2F2	33	13	46	5272.586
#17	E2F5	33	12	45	9090.025
#18	MEOX2	32	8	40	2571.654
#19	FOXM1	32	7	39	1375.304
#20	KLF4	31	9	40	1012.538
#21	ZNF131	31	9	40	1342.872
#22	AHR	30	12	42	2770.561
#23	MAFB	30	12	42	2046.897
#24	TBX2	30	7	37	1300.378
#25	NR2F6	30	7	37	665.319
#26	CNOT8	30	10	40	3250.497
#27	TRIM22	29	12	41	2595.676
#28	STAT5A	29	10	39	929.694
#29	CEBPD	29	7	36	1064.094
#30	SUPT4H1	29	9	38	1314.58
#31	RXRB	29	5	34	660.922
#32	IRF8	28	6	34	1470.974
#33	NFYB	27	8	35	877.576
#34	MAF	27	10	37	2802.141
#35	HSF1	27	12	39	696.502
#36	TSC22D1	27	8	35	246.68
#37	TFEB	26	8	34	2281.721
#38	CREB3L1	25	7	32	1356.244
#39	NFATC4	25	14	39	1684.049
#40	SMAD4	25	7	32	2018.046
#41	TP53	24	5	29	871.315
#42	AHCTF1	24	10	34	1486.552
#43	TSC22D3	24	11	35	1042.675
#44	KLF2	24	7	31	266.031
#45	SPI1	23	7	30	329.336
#46	REXO4	23	9	32	1664.647
#47	MLL	23	7	30	534.728
#48	ZNF643	22	11	33	4348.641
#49	IRF7	22	10	32	1630.561
#50	SOX4	22	14	36	1573.268
#51	HMGA1	22	14	36	977.556
#52	HLF	22	11	33	1743.163
#53	HOXC10	22	12	34	1387.869
#54	ZNF217	21	12	33	886.05
#55	ELF1	21	14	35	2124.842
#56	GRHL2	21	8	29	2123.105
#57	IRF6	21	10	31	310.628
#58	NR2F1	21	9	30	502.865
#59	NR4A3	21	6	27	576.913
#60	FOS	20	10	30	2027.563
#61	POU3F4	20	7	27	2693.245
#62	LEF1	20	8	28	246.826
#63	TCF25	20	6	26	624.276
#64	KLF9	19	13	32	1541.364
#65	TCF12	19	9	28	1607.046
#66	EGR2	19	10	29	751.1
#67	FOXF1	19	9	28	125.798
#68	TP73	19	14	33	2256.211
#69	FOSB	19	9	28	261.644
#70	TBX5	19	15	34	1187.405
#71	NR2E3	19	8	27	2464.574
#72	UBN1	19	3	22	219.672
#73	HOXA5	19	11	30	862.841
#74	HNF1B	19	12	31	1362.492
#75	NFYA	19	10	29	780.215
#76	GATAD1	18	12	30	785.381
#77	ZNF83	18	8	26	1825.012
#78	ZFPM2	18	12	30	700.431
#79	RAX	18	9	27	2169.804
#80	HCLS1	18	5	23	264.172
#81	GATA6	18	12	30	3710.888
#82	FLI1	18	11	29	646.158
#83	TFDP1	18	13	31	1565.303
#84	NR4A1	18	9	27	421.665
#85	SMAD5	18	11	29	1584.846
#86	FOXA1	18	10	28	2947.424
#87	GAS7	18	11	29	2117.127
#88	POU6F2	18	8	26	692.992
#89	MEIS1	18	7	25	179.024
#90	GTF2H3	17	8	25	4375.359
#91	REL	17	10	27	1287.743
#92	NKX2-1	17	11	28	583.909
#93	SPEN	17	8	25	1674.145
#94	TAF1B	17	13	30	3649.576
#95	ZNF45	17	13	30	2814.304
#96	REST	17	13	30	3314.561
#97	ZNF75D	16	13	29	1480.992
#98	ZEB2	16	10	26	638.528
#99	ZSCAN16	16	10	26	1022.409
#100	SNAI2	16	10	26	2782.877
#101	MAFF	16	7	23	307
#102	ELF3	16	9	25	643.105
#103	FOSL1	16	15	31	1855.634
#104	MAX	16	13	29	1291.565
#105	TAL1	16	9	25	356.266
#106	NFATC3	16	9	25	2969.439
#107	CBFA2T3	16	11	27	547.123
#108	SMAD1	16	14	30	1370.22
#109	MGA	16	11	27	2394.473
#110	MYC	15	8	23	521.46
#111	BHLHE41	15	13	28	1388.438
#112	TFAM	15	5	20	443.511
#113	NR1D2	15	10	25	1257.733
#114	JUNB	15	5	20	118.041
#115	SIM2	15	10	25	1666.479
#116	AEBP1	15	9	24	1240.633
#117	ZBTB48	15	13	28	2595.704
#118	PLSCR1	15	9	24	2191.81
#119	CEBPE	15	8	23	1673.025
#120	FOXN2	15	12	27	2574.433
#121	CBFB	15	6	21	419.944
#122	ZNF192	14	9	23	3589.522
#123	SATB1	14	13	27	1120.633
#124	SOX21	14	7	21	785.862
#125	TBX19	14	8	22	804.006
#126	ETV4	14	15	29	351.768
#127	NR3C2	14	13	27	2389.103
#128	HMGA2	14	13	27	656.753
#129	SUPT6H	14	14	28	2306.68
#130	DLX2	14	12	26	786.175
#131	C2orf3	14	8	22	1128.155
#132	ZBTB25	14	12	26	2837.445
#133	E2F8	14	11	25	651.041
#134	HIRA	14	15	29	1589.452
#135	TBX3	14	13	27	1289.926
#136	CREB5	13	16	29	2365.296
#137	FOXO4	13	15	28	1469.466
#138	FOXD1	13	13	26	1404.935
#139	SMAD6	13	13	26	2150.546
#140	ZEB1	13	11	24	435.839
#141	LHX2	13	7	20	309.024
#142	KLF11	13	9	22	360.042
#143	SOX13	13	12	25	1740.393
#144	CREB1	13	6	19	314.207
#145	ZNF134	13	10	23	1627.486
#146	FOXF2	13	12	25	280.422
#147	STAT6	13	14	27	3009.468
#148	NR3C1	13	13	26	3733.201
#149	RARA	13	14	27	1638.806
#150	GTF2I	13	10	23	1130.706
#151	SRF	13	9	22	525.44
#152	FOXJ1	13	8	21	767.598
#153	EGR1	13	6	19	234.488
#154	ARNTL2	12	8	20	975.168
#155	MYBL2	12	14	26	391.774
#156	ZNF167	12	11	23	946.406
#157	WNT5A	12	12	24	1508.733
#158	ALS2CR8	12	7	19	717.223
#159	HR	12	9	21	801.461
#160	MEF2C	12	14	26	780.108
#161	SCML1	12	8	20	952.745
#162	SOX17	12	8	20	419.378
#163	GBX2	12	12	24	2201.867
#164	HOXC13	12	12	24	990.393
#165	FOXA2	12	15	27	1108.973
#166	STAT2	12	13	25	2224.72
#167	BATF	12	15	27	1017.35
#168	MEOX1	12	14	26	1359.229
#169	TBX6	12	12	24	2181.474
#170	GABPB1	12	10	22	538.266
#171	VSX1	12	9	21	2099.48
#172	GABPA	12	6	18	196.77
#173	ZNF24	12	11	23	935.954
#174	HOXB9	12	15	27	2302.816
#175	STAT3	12	12	24	860.058
#176	MYT1L	12	7	19	1559.559
#177	ETV1	12	13	25	919.37
#178	NR5A1	12	11	23	1872.612
#179	JUND	12	9	21	650.898
#180	MYCL1	12	8	20	1197.698
#181	TWIST1	12	15	27	1581.879
#182	PITX1	12	15	27	773.657
#183	FOXO1	12	12	24	1678.414
#184	ALX1	11	10	21	512.987
#185	C11orf9	11	11	22	2246.215
#186	FOXD2	11	16	27	2066.56
#187	PKNOX2	11	10	21	759.981
#188	MEF2D	11	10	21	1384.385
#189	TFAP2A	11	14	25	651.257
#190	POU3F2	11	11	22	1626.853
#191	ZIC3	11	13	24	2527.764
#192	E2F1	11	8	19	916.8
#193	MECOM	11	11	22	531.759
#194	HSF2	11	16	27	2962.912
#195	RUNX1T1	11	11	22	487.246
#196	EGR3	11	9	20	743.079
#197	ETV5	11	15	26	1952.742
#198	CITED2	11	16	27	1513.082
#199	ZFP36L2	11	10	21	954.413
#200	MZF1	11	12	23	1624.529
#201	TEAD4	11	9	20	1172.76
#202	HOXA6	11	10	21	2712.164
#203	PRRX2	11	12	23	1009.231
#204	PHOX2B	11	10	21	1359.454
#205	SRY	11	12	23	2168.971
#206	PAX5	11	14	25	3631.008
#207	HOXD13	10	13	23	1681.615
#208	SOX9	10	12	22	564.224
#209	RB1	10	11	21	1255.031
#210	YEATS4	10	15	25	923.646
#211	ARNT	10	8	18	700.774
#212	KLF10	10	10	20	401.23
#213	BCL6	10	12	22	1792.436
#214	ST18	10	16	26	3514.22
#215	HSF4	10	11	21	1179.966
#216	ISL1	10	10	20	794.622
#217	RCAN1	10	7	17	1564.377
#218	HOXD9	10	13	23	1671.095
#219	MSRB2	10	11	21	363.586
#220	ATF3	10	8	18	209.076
#221	RXRA	10	14	24	2699.999
#222	NKX2-8	10	18	28	2920.283
#223	TCF7L2	10	16	26	1142.506
#224	IKZF3	10	13	23	1835.928
#225	BHLHE40	10	13	23	978.396
#226	RORB	10	14	24	1868.853
#227	KDM5A	10	9	19	1343.236
#228	CRX	10	9	19	876.472
#229	HOXA4	10	13	23	760.78
#230	TFEC	10	6	16	233.275
#231	PPARG	10	14	24	507.056
#232	FOXO3	10	11	21	767.182
#233	HMX1	10	10	20	1121.301
#234	ZNF41	10	11	21	1741.047
#235	ZNF33B	9	9	18	1637.841
#236	HOXA10	9	15	24	694.15
#237	BARX1	9	12	21	1226.24
#238	NFAT5	9	11	20	1650.711
#239	CDKN2A	9	13	22	1788.29
#240	SIX3	9	13	22	1005.941
#241	SMAD3	9	17	26	1505.025
#242	TLX3	9	16	25	1408.804
#243	ZNF236	9	14	23	1567.785
#244	MEF2A	9	10	19	928.955
#245	HOXC8	9	10	19	880.476
#246	NR2E1	9	9	18	1054.094
#247	NFATC1	9	10	19	776.463
#248	FOXL2	9	12	21	1434.035
#249	ELK4	9	8	17	699.797
#250	ESR2	9	8	17	718.823
#251	TADA3	9	12	21	991.976
#252	GATA4	9	11	20	4296.408
#253	HAND1	9	14	23	1254.448
#254	ZNF444	9	12	21	1242.626
#255	BCL3	9	9	18	1299.832
#256	RUNX2	9	10	19	1646.389
#257	PPBPL2	9	11	20	1363.581
#258	MSX1	9	17	26	754.337
#259	ZFP37	9	12	21	944.997
#260	NKX3-2	9	8	17	152.998
#261	HOXD11	9	13	22	1471.163
#262	KLF15	9	10	19	897.392
#263	ONECUT2	9	7	16	4090.981
#264	BUD31	9	12	21	1437.835
#265	CTBP1	9	12	21	1329.796
#266	KLF1	9	15	24	9474.119
#267	HOXA1	8	13	21	759.81
#268	BACH1	8	10	18	2115.086
#269	TAF4	8	9	17	867.571
#270	ZGPAT	8	11	19	1190.595
#271	HINFP	8	10	18	2217.104
#272	PRDM1	8	13	21	1150.056
#273	TBX1	8	14	22	1155.399
#274	FOSL2	8	13	21	706.747
#275	PKNOX1	8	12	20	2141.88
#276	ARNTL	8	17	25	783.773
#277	NPAS2	8	13	21	571.412
#278	TCF3	8	13	21	280.291
#279	CSDA	8	11	19	4297.547
#280	TRIM25	8	5	13	165.816
#281	AR	8	12	20	1436.821
#282	CEBPA	8	10	18	645.052
#283	CBL	8	12	20	1346.646
#284	TFAP2C	8	9	17	587.575
#285	SPDEF	8	13	21	423.601
#286	KLF6	8	12	20	514.089
#287	HNF1A	8	13	21	383.397
#288	MBD1	8	15	23	714.236
#289	PPARA	8	12	20	5018.069
#290	RFXAP	8	8	16	131.462
#291	PBX1	8	15	23	584.507
#292	VAX2	8	16	24	3181.745
#293	NFX1	8	11	19	835.289
#294	VTN	8	11	19	2088.964
#295	MNX1	8	11	19	202.617
#296	ZKSCAN1	8	6	14	481.639
#297	ZNF81	8	11	19	1577.639
#298	HOXB7	8	13	21	896.279
#299	ESRRB	8	13	21	1572.598
#300	ZNF157	8	14	22	1211.032
#301	TP63	8	16	24	1700.424
#302	TSHZ2	8	11	19	927.579
#303	NANOG	8	16	24	882.685
#304	MYCN	8	14	22	1534.865
#305	HOXA7	8	11	19	1182.382
#306	VDR	8	15	23	803.159
#307	ZXDC	8	14	22	1219.058
#308	IKZF1	8	16	24	2920.481
#309	TFDP2	8	10	18	982.123
#310	T	7	11	18	624.59
#311	SNAPC5	7	9	16	331.471
#312	HOXB3	7	12	19	1395.72
#313	TAF12	7	19	26	397.742
#314	POU6F1	7	10	17	665.141
#315	CSRNP3	7	14	21	1390.765
#316	POU2F2	7	16	23	1103.578
#317	ZNF155	7	10	17	809.727
#318	FOXH1	7	12	19	621.706
#319	NR4A2	7	12	19	344.74
#320	ZNF174	7	11	18	1399.175
#321	ZNF117	7	15	22	647.843
#322	E2F2	7	15	22	475.927
#323	PDX1	7	10	17	886.607
#324	RERE	7	17	24	734.85
#325	ZSCAN12	7	7	14	478.676
#326	FOXI1	7	13	20	2556.918
#327	MYF5	7	11	18	773.855
#328	NPAT	7	15	22	2483.793
#329	GATA3	7	16	23	1883.964
#330	TBR1	7	8	15	1496.346
#331	SOX2	7	14	21	1286.121
#332	ZNF91	7	12	19	679.966
#333	ZFP36L1	7	13	20	735.813
#334	HOXA2	7	10	17	1015.274
#335	POU3F1	7	14	21	1052.382
#336	TBX10	7	12	19	1013.092
#337	PAX6	7	10	17	423.302
#338	PAX4	7	9	16	1215.307
#339	ESR1	7	16	23	943.323
#340	HIF3A	7	9	16	210.389
#341	GLI2	7	14	21	1239.418
#342	ERF	7	15	22	1070.395
#343	SOX30	6	11	17	1167.864
#344	GCM1	6	9	15	582.105
#345	ZNF238	6	10	16	1248.183
#346	CBFA2T2	6	12	18	959.174
#347	SNAPC4	6	15	21	819.012
#348	CREM	6	8	14	252.106
#349	MLXIPL	6	13	19	1303.736
#350	DMRT1	6	11	17	879.279
#351	FOXE1	6	12	18	494.988
#352	HEY2	6	12	18	752.698
#353	PLAG1	6	10	16	437.798
#354	NPAS1	6	11	17	1301.135
#355	HOXB6	6	14	20	3220.541
#356	SCRT1	6	13	19	2018.8
#357	ELK3	6	11	17	1878.058
#358	ATF5	6	14	20	853.295
#359	NFE2	6	13	19	1156.58
#360	EN2	6	14	20	1017.401
#361	SALL1	6	13	19	1552.105
#362	HEY1	6	23	29	1672.361
#363	STAT1	6	15	21	330.508
#364	MLLT10	6	13	19	555.991
#365	OLIG2	6	15	21	983.952
#366	HMG20B	6	19	25	4058.696
#367	FOXG1	6	11	17	148.135
#368	ESRRG	6	12	18	524.925
#369	PRRX1	6	9	15	521.027
#370	BLZF1	5	11	16	668.599
#371	AFF1	5	9	14	725.454
#372	ZNF434	5	14	19	473.98
#373	ELK1	5	11	16	583.772
#374	NFIX	5	12	17	886.15
#375	NFKB2	5	10	15	613.128
#376	SIM1	5	17	22	844.115
#377	NR0B1	5	13	18	938.697
#378	MXD1	5	13	18	447.022
#379	RARG	5	14	19	1231.02
#380	STRN3	5	16	21	1306.109
#381	POU5F1B	5	6	11	945.38
#382	ZNF202	5	11	16	666.888
#383	TCF7	5	14	19	1145.522
#384	NEUROG1	5	13	18	1668.75
#385	KLF12	5	12	17	1445.174
#386	MAFK	5	16	21	805.509
#387	TBX4	5	7	12	109.044
#388	NRL	5	12	17	1295.11
#389	ALX3	5	13	18	985.2
#390	ATOH1	5	8	13	366.205
#391	PPARD	5	11	16	880.525
#392	RBPJL	5	14	19	798.491
#393	CUX2	5	16	21	1797.242
#394	HOXB1	5	9	14	395.397
#395	HES1	5	15	20	1155.196
#396	EMX1	5	12	17	477.259
#397	IRF5	5	11	16	627.104
#398	PHOX2A	5	13	18	1129.865
#399	ZNF215	5	11	16	363.309
#400	EGR4	5	15	20	3013.487
#401	SOX11	5	11	16	697.815
#402	IRF4	5	16	21	1115.792
#403	JUN	5	12	17	472.7
#404	EHF	5	12	17	241.743
#405	MYF6	5	12	17	788.688
#406	ZNF446	5	8	13	1335.964
#407	ZIC1	5	10	15	449.078
#408	NFIC	5	8	13	682.689
#409	GSC2	5	15	20	2059.761
#410	MTA2	5	13	18	934.915
#411	TADA2A	5	8	13	270.066
#412	ZNF165	5	18	23	855.85
#413	ETV2	5	15	20	940.345
#414	EN1	4	16	20	788.642
#415	POU3F3	4	9	13	852.284
#416	IRX4	4	13	17	450.68
#417	HNF4A	4	9	13	230.524
#418	FOXP3	4	12	16	1111.35
#419	WT1	4	12	16	228.47
#420	LHX1	4	13	17	1159.179
#421	ZNF154	4	9	13	579.323
#422	NKX2-5	4	14	18	197.949
#423	TCF15	4	11	15	277.167
#424	ZNF80	4	10	14	350.86
#425	POU1F1	4	12	16	1470.786
#426	BRD8	4	13	17	371.416
#427	HOXA3	4	14	18	1194.676
#428	SCAND2	4	12	16	968.761
#429	ZSCAN2	4	14	18	692.066
#430	ASCL1	4	16	20	873.242
#431	PTH	4	14	18	593.834
#432	NR1H4	4	11	15	558.868
#433	PROX1	4	11	15	1302.786
#434	NR5A2	4	12	16	599.637
#435	TSC22D2	4	11	15	947.161
#436	DLX6	4	9	13	434.047
#437	TRIM29	4	13	17	669.546
#438	PGR	4	12	16	2174.905
#439	ATF6B	4	10	14	270.654
#440	ARNT2	4	9	13	241.693
#441	KDM5B	4	8	12	776.748
#442	ZNF3	4	11	15	522.901
#443	HOXA9	3	12	15	328.35
#444	FOXD3	3	8	11	148.058
#445	ATF6	3	8	11	167.49
#446	TFAP2B	3	10	13	531.444
#447	NR6A1	3	13	16	519.054
#448	YY1	3	13	16	913.908
#449	MSX2	3	19	22	940.551
#450	ZNF287	3	13	16	679.422
#451	CITED1	3	11	14	352.455
#452	LZTS1	3	12	15	419.68
#453	HOXD4	3	14	17	693.376
#454	GTF2H4	3	10	13	527.111
#455	RARB	3	9	12	440.546
#456	ELF5	3	9	12	354.102
#457	TLX2	3	7	10	914.979
#458	HESX1	3	12	15	637.237
#459	HNF4G	3	14	17	715.328
#460	PAX3	3	19	22	407.746
#461	THRA	3	11	14	278.355
#462	FOXE3	3	16	19	326.48
#463	DBP	3	12	15	921.118
#464	HOXD3	3	13	16	1204.266
#465	FOXC2	3	12	15	198.883
#466	BNC1	3	11	14	453.339
#467	NFIB	3	10	13	123.555
#468	CREBZF	3	12	15	2034.817
#469	GATA1	3	13	16	696.64
#470	SP1	3	10	13	448.789
#471	ELF4	3	15	18	498.913
#472	PAX8	3	13	16	412.114
#473	PRDM2	3	14	17	621.976
#474	ZHX3	2	11	13	229.41
#475	MMP14	2	12	14	337.466
#476	NEUROD1	2	15	17	922.035
#477	ZNF639	2	13	15	155.775
#478	MSC	2	11	13	282.278
#479	HOXA11	2	12	14	330.215
#480	NR1I2	2	8	10	248.16
#481	NR2C1	2	12	14	1483.28
#482	POU4F1	2	11	13	279.432
#483	SIX1	2	15	17	651.58
#484	IRX5	2	10	12	355.612
#485	POU2F3	2	11	13	850.783
#486	OVOL1	2	16	18	352.049
#487	CREBBP	2	12	14	267.827
#488	TFDP3	2	11	13	457.98
#489	TEF	2	17	19	1453.251
#490	PITX2	2	12	14	280.566
#491	ZNF135	2	8	10	172.57
#492	SOX18	2	17	19	730.039
#493	ZSCAN18	2	14	16	401.364
#494	ONECUT1	1	16	17	185.485
#495	HIC1	1	13	14	211.162
#496	SLC26A3	1	19	20	346.066
#497	TAF13	1	12	13	131.578
#498	HOXD1	1	12	13	75.876
#499	POU4F3	1	15	16	199.207
#500	SATB2	0	16	16	0