Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ENO1	54	2	56	1290.645
#2	PTTG1	46	1	47	352.414
#3	RCAN1	43	5	48	517.903
#4	FOXM1	43	2	45	743.554
#5	SOX13	41	2	43	524.286
#6	NFIA	41	7	48	6229.999
#7	ETS2	39	4	43	1334.701
#8	PEG3	38	11	49	5930.506
#9	ZEB2	38	6	44	1582.88
#10	HMGB2	37	5	42	1050.174
#11	TRIM28	36	3	39	106.096
#12	NFIC	35	9	44	3056.662
#13	GTF2I	34	2	36	192.049
#14	AATF	33	7	40	1754.02
#15	E2F8	33	4	37	485.712
#16	NR1I2	32	12	44	958.712
#17	E2F7	31	8	39	2142.789
#18	JUNB	31	1	32	48.513
#19	NR3C2	30	11	41	2514.663
#20	HMGA1	29	6	35	446.852
#21	BACH2	29	7	36	544.957
#22	NR1H4	29	8	37	3423.404
#23	MEIS3P1	28	12	40	3106.9
#24	KDM5A	27	2	29	37.73
#25	ZNF148	27	3	30	2056.272
#26	CREB3L2	27	8	35	1126.346
#27	AEBP1	27	3	30	650.297
#28	FOXN3	26	5	31	256.92
#29	PHF5A	26	10	36	2390.694
#30	TAF4	26	7	33	2970.605
#31	HDAC1	26	10	36	2024.465
#32	JDP2	26	7	33	3124.643
#33	TCF4	26	5	31	1188.999
#34	CDKN2A	25	11	36	1788.796
#35	IRF6	25	8	33	1496.569
#36	ZIC2	25	9	34	1700.47
#37	HCLS1	25	3	28	1501.302
#38	MLX	24	5	29	746.525
#39	ADNP	24	10	34	1212.192
#40	ONECUT2	24	11	35	979.142
#41	ESR1	24	8	32	845.668
#42	ZNF189	24	6	30	518.208
#43	NOLC1	23	9	32	2276.777
#44	MAX	23	5	28	119.46
#45	CREBL2	23	10	33	4055.772
#46	MLXIPL	23	7	30	1303.611
#47	YY1	22	4	26	205.753
#48	PLAGL2	22	9	31	2904.568
#49	NFIL3	22	1	23	17.05
#50	IKZF1	22	0	22	0
#51	ZFHX4	22	11	33	6909.038
#52	PRDM1	22	2	24	58.105
#53	ATF3	22	8	30	1271.017
#54	NFE2L2	21	7	28	1422.593
#55	TCF19	21	6	27	1605.982
#56	SLC2A4RG	21	9	30	1551.334
#57	SMAD2	21	8	29	1275.494
#58	TSHZ2	21	10	31	5218.668
#59	EPAS1	21	9	30	1086.414
#60	YBX1	20	2	22	74.75
#61	UHRF1	20	6	26	767.389
#62	HSF2	20	10	30	1250.573
#63	NFIX	20	4	24	696.774
#64	HOXA3	20	11	31	2014.826
#65	FOXF1	19	8	27	3707.403
#66	ZSCAN29	19	10	29	2250.988
#67	NR1I3	19	16	35	5077.308
#68	ZGPAT	19	12	31	1130.296
#69	CSRNP1	19	8	27	2403.073
#70	FLI1	19	3	22	411.295
#71	HLF	19	19	38	7712.357
#72	IRF8	19	12	31	1038.333
#73	RELA	19	10	29	641.678
#74	HNRNPAB	19	8	27	1274.659
#75	AR	19	9	28	413.765
#76	LASS2	19	11	30	2432.432
#77	ZFPM2	19	5	24	723.307
#78	ZFHX3	18	5	23	567.895
#79	GATAD2A	18	6	24	2693.757
#80	CBFB	18	9	27	862.608
#81	RFX5	18	14	32	1916.168
#82	STAT2	18	5	23	2115.376
#83	ARID4A	18	7	25	2290.417
#84	VTN	17	10	27	1635.855
#85	HOXA13	17	13	30	3314.388
#86	POU2F1	17	17	34	3290.805
#87	TULP4	17	7	24	915.312
#88	CREM	17	9	26	1412.02
#89	NR3C1	17	7	24	3465.4
#90	NFYA	17	13	30	1632.28
#91	SATB1	16	10	26	3667.008
#92	MLLT10	16	7	23	1873.963
#93	CITED2	16	13	29	1012.699
#94	E2F3	16	15	31	1985.087
#95	ATF1	16	8	24	1078.807
#96	BCL3	16	7	23	822.772
#97	FOXK1	16	8	24	508.042
#98	MGA	16	7	23	1025.102
#99	HDAC2	16	9	25	994.409
#100	AHCTF1	16	6	22	1134.268
#101	FOS	16	5	21	867.503
#102	E2F5	15	7	22	1312.759
#103	ZSCAN16	15	7	22	878.927
#104	SOX9	15	10	25	2617.503
#105	TBX3	15	7	22	4704.063
#106	ZNF83	15	14	29	4221.39
#107	RBCK1	15	12	27	4614.722
#108	RUNX2	15	6	21	666.337
#109	SIX1	15	12	27	2579.309
#110	EOMES	15	5	20	2044.997
#111	PLSCR1	15	12	27	1178.424
#112	GATA3	15	6	21	1520.028
#113	MITF	15	10	25	2798.976
#114	TCF12	15	5	20	1530.955
#115	TP53	15	15	30	1164.527
#116	MTA1	14	7	21	918.357
#117	NFYC	14	11	25	2483.667
#118	ZNF217	14	11	25	1795.087
#119	BHLHE40	14	13	27	2340.304
#120	RORC	14	13	27	859.128
#121	E2F6	14	9	23	2335.414
#122	FOSL2	14	9	23	1831.766
#123	SALL2	14	9	23	2443.674
#124	TFDP2	14	7	21	3996.953
#125	RXRA	14	9	23	2664.183
#126	ARID3A	14	10	24	1835.516
#127	GTF2H2	14	10	24	705.914
#128	PBX1	14	12	26	1103.431
#129	MAFF	14	8	22	1703.896
#130	PBX3	14	11	25	1712.876
#131	TCFL5	13	10	23	1838.208
#132	ZSCAN18	13	9	22	3099.29
#133	KLF9	13	11	24	611.325
#134	RUNX1	13	12	25	1558.707
#135	TBX15	13	15	28	1632.806
#136	GATA6	13	15	28	2405.372
#137	TCEAL1	13	12	25	5725.783
#138	TRIM22	13	13	26	762.98
#139	NR2F6	13	12	25	1889.554
#140	HNF4A	13	9	22	1184.4
#141	ZNF323	13	7	20	1749.205
#142	HMGB1	13	12	25	1908.61
#143	EBF1	12	10	22	711.073
#144	PLAG1	12	10	22	1075.656
#145	SP4	12	11	23	1061.17
#146	ATF7	12	11	23	976.338
#147	XBP1	12	11	23	1098.365
#148	GLIS2	12	16	28	3217.175
#149	KLF2	12	8	20	457.238
#150	NFXL1	12	12	24	1731.78
#151	ATF2	12	8	20	1225.04
#152	CSDA	12	12	24	3057.731
#153	TAF12	12	10	22	2285.253
#154	KLF6	12	13	25	1541.597
#155	FOXA3	12	6	18	1540.931
#156	TCF21	12	11	23	779.5
#157	TAF6	12	5	17	87.965
#158	GTF2IRD1	12	13	25	869.414
#159	LEF1	11	12	23	520.427
#160	MAF	11	13	24	1102.755
#161	UBN1	11	12	23	3236.655
#162	MYC	11	12	23	1341.639
#163	CREB3	11	12	23	1957.023
#164	PURB	11	14	25	3486.027
#165	ZNF277	11	11	22	1466.724
#166	SIX5	11	9	20	628.094
#167	ZNF238	11	13	24	2878.854
#168	TSC22D2	11	13	24	1997.341
#169	HNF1B	11	11	22	2232.136
#170	FOXK2	11	16	27	911.928
#171	TFEC	11	11	22	1536.419
#172	STAT1	11	10	21	854.389
#173	CEBPA	11	17	28	1725.741
#174	MXD1	11	5	16	1245.565
#175	FOXP4	11	9	20	4235.72
#176	TAF5	11	13	24	482.543
#177	TCF7L1	11	12	23	3069.186
#178	JUN	11	6	17	1430.617
#179	EGR2	10	7	17	200.132
#180	NFE2L3	10	16	26	1500.953
#181	CTNNB1	10	13	23	1557.74
#182	RUNX3	10	7	17	619.661
#183	ISX	10	15	25	3606.946
#184	TEAD2	10	16	26	2094.131
#185	HOXA10	10	12	22	1135.538
#186	SOX4	10	11	21	1046.612
#187	ZNF131	10	14	24	1549.744
#188	ATF5	10	12	22	1165.702
#189	GABPA	10	3	13	137.819
#190	SMAD6	10	11	21	1139.834
#191	ZNF140	10	14	24	2658.385
#192	MEF2C	10	5	15	1079.38
#193	IRF9	10	9	19	1131.29
#194	NKX3-1	10	18	28	2662.204
#195	HIF1A	10	14	24	1742.973
#196	ETS1	10	7	17	1031.466
#197	ARNTL2	10	10	20	1971.879
#198	FUBP1	10	7	17	462.432
#199	NR4A3	10	13	23	817.893
#200	SUPT4H1	10	6	16	552.286
#201	TAF4B	10	11	21	1532.155
#202	CEBPB	10	9	19	1693.473
#203	TEAD1	10	6	16	402.14
#204	TBX4	10	7	17	1832.615
#205	TSC22D1	10	17	27	3248.647
#206	MYBL2	10	2	12	9.677
#207	PPARD	10	12	22	2687.137
#208	HOXD1	10	4	14	5046.593
#209	SALL1	10	13	23	1636.295
#210	TSHZ3	9	11	20	759.188
#211	SLC26A3	9	9	18	2044.037
#212	HMGA2	9	3	12	32.713
#213	IRX3	9	11	20	809.068
#214	SATB2	9	14	23	1360.657
#215	SNAI2	9	14	23	1094.365
#216	GLIS3	9	12	21	1138.809
#217	HOXD4	9	13	22	4018.619
#218	IRF4	9	9	18	2861.518
#219	HEY1	9	14	23	761.336
#220	ZFP36L1	9	15	24	1530.279
#221	PROX1	9	16	25	2832.201
#222	PPARA	9	12	21	842.605
#223	HEY2	9	8	17	809.291
#224	FOXA2	9	10	19	1363.758
#225	ZNF24	9	13	22	2219.645
#226	BCL6	9	8	17	983.11
#227	KDM5B	9	16	25	4386.006
#228	BACH1	9	8	17	507.283
#229	CBFA2T2	9	8	17	1734.993
#230	ZNF496	9	12	21	1371.017
#231	C11orf9	9	11	20	1721.261
#232	ZKSCAN1	9	12	21	1983.83
#233	JUND	9	14	23	1784.397
#234	HOXB2	9	8	17	271.467
#235	SMAD5	9	12	21	1901.179
#236	NCOR1	9	11	20	692.817
#237	SIX4	9	10	19	3363.49
#238	ZHX1	9	17	26	977.24
#239	ELK3	9	7	16	881.262
#240	ZHX3	9	7	16	1369.293
#241	SMAD4	9	9	18	1675.703
#242	TFEB	9	12	21	1039.212
#243	TARDBP	9	12	21	1036.231
#244	ATF4	9	13	22	1472.581
#245	HCFC1	9	7	16	1355.139
#246	MTF1	9	7	16	313.68
#247	ZSCAN5A	9	8	17	82.61
#248	ETV4	8	9	17	455.384
#249	HOXA2	8	7	15	773.657
#250	RARA	8	9	17	853.595
#251	GTF2H4	8	10	18	876.237
#252	EGR1	8	8	16	1488.057
#253	SOX2	8	10	18	1744.992
#254	RARB	8	8	16	735.257
#255	KLF4	8	16	24	1783.378
#256	GABPB1	8	12	20	2522.993
#257	FOXN4	8	7	15	663.895
#258	ZKSCAN3	8	9	17	403.124
#259	NR2F2	8	10	18	1783.485
#260	NR4A2	8	14	22	1706.255
#261	RUNX1T1	8	8	16	2164.674
#262	MYCL1	8	14	22	1332.654
#263	FOXN2	8	13	21	641.183
#264	SREBF1	8	13	21	1382.639
#265	SUPT6H	8	8	16	728.535
#266	CCRN4L	8	6	14	299.244
#267	NFATC1	8	7	15	327.704
#268	CREBBP	8	11	19	1579.072
#269	ZSCAN21	8	7	15	787.92
#270	MAFG	8	10	18	1038.145
#271	LCOR	8	12	20	1053.888
#272	SPEN	8	6	14	554.851
#273	RB1	8	13	21	2124.179
#274	MLL	8	15	23	1471.468
#275	ZFP36L2	8	14	22	1476.628
#276	KLF15	8	14	22	950.862
#277	PCGF2	8	11	19	1396.439
#278	NFYB	8	9	17	2386.313
#279	KLF3	7	8	15	1393.3
#280	MSX1	7	12	19	2306.391
#281	SMAD3	7	15	22	955.34
#282	EHF	7	17	24	2064.821
#283	ZNF45	7	15	22	1643.821
#284	ZNF639	7	10	17	1065.512
#285	MAFK	7	9	16	452.386
#286	ZSCAN2	7	9	16	877.225
#287	ZNF449	7	8	15	659.18
#288	TSC22D3	7	14	21	1067.714
#289	SMAD9	7	16	23	1745.134
#290	KLF12	7	11	18	724.807
#291	TBX2	7	9	16	1049.252
#292	PAX6	7	5	12	393.024
#293	BCL11B	7	10	17	629.466
#294	ELF3	7	17	24	2216.173
#295	TFCP2	7	8	15	1203.282
#296	HEYL	7	12	19	1263.175
#297	RERE	7	10	17	1479.941
#298	EGR3	7	9	16	568.744
#299	ZNF281	7	13	20	774.925
#300	IRF1	7	14	21	3228.357
#301	SIN3A	7	12	19	2647.757
#302	ELF4	7	12	19	1947.391
#303	SREBF2	7	13	20	852.692
#304	RORA	7	16	23	1473.366
#305	SP140	6	8	14	799.352
#306	SOX12	6	10	16	1458.143
#307	KLF7	6	10	16	1641.809
#308	TEF	6	8	14	817.633
#309	HNF4G	6	11	17	1775.331
#310	NFIB	6	13	19	1557.045
#311	HOXB3	6	13	19	1724.573
#312	ZEB1	6	9	15	901.187
#313	SCML1	6	12	18	1115.215
#314	ZNF91	6	10	16	589.532
#315	IRF7	6	9	15	2138.646
#316	PBX2	6	12	18	1787.954
#317	FOXP1	6	11	17	1546.725
#318	HHEX	6	12	18	2505.665
#319	FBXW7	6	9	15	1820.535
#320	SOX7	6	15	21	1235.336
#321	C5orf41	6	16	22	600.214
#322	MMP14	6	9	15	507.425
#323	GAS7	6	9	15	734.048
#324	YEATS4	6	10	16	1436.717
#325	PA2G4	6	10	16	537.16
#326	ELF1	6	11	17	972.378
#327	ZNF165	6	15	21	2750.368
#328	TSHZ1	6	12	18	442.376
#329	CEBPD	6	13	19	2436.418
#330	WNT5A	6	8	14	312.341
#331	SOLH	6	16	22	949.31
#332	CUX1	6	17	23	836.367
#333	ZNF138	6	7	13	1071.681
#334	NFKB2	6	11	17	958.598
#335	ZKSCAN4	6	9	15	1448.85
#336	ZNF92	5	11	16	348.399
#337	TAF13	5	9	14	1697.656
#338	CBL	5	11	16	789.254
#339	KLF10	5	12	17	1948.228
#340	BHLHE41	5	9	14	380.595
#341	ZFPM1	5	10	15	2038.649
#342	NR5A2	5	15	20	2066.024
#343	PGBD1	5	8	13	201.633
#344	TRERF1	5	7	12	592.172
#345	DLX1	5	3	8	288.032
#346	CREBZF	5	8	13	494.183
#347	MEIS2	5	17	22	1534.651
#348	NFE2L1	5	17	22	1673.27
#349	HES1	5	6	11	460.612
#350	KLF11	5	12	17	242.866
#351	ERG	5	8	13	277.699
#352	TRPS1	5	16	21	1769.402
#353	HOPX	5	13	18	455.636
#354	AHR	5	10	15	961.308
#355	ZNF117	5	12	17	1885.662
#356	ZNF193	5	12	17	663.835
#357	NR4A1	5	11	16	1196.333
#358	NANOGNB	5	9	14	298.51
#359	ZBTB38	5	16	21	2046.644
#360	ZNF397	5	8	13	995.07
#361	CREB3L3	5	17	22	2113.715
#362	NFATC2	5	10	15	1724.114
#363	GCFC1	5	12	17	2203.848
#364	CNOT7	5	14	19	3186.564
#365	FOXO3	4	15	19	476.287
#366	SP1	4	8	12	262.786
#367	HOXA5	4	9	13	1528.548
#368	MKX	4	15	19	1024.494
#369	MYCN	4	16	20	1907.653
#370	DLX2	4	3	7	162.502
#371	TRIM25	4	13	17	830.492
#372	BATF2	4	9	13	472.253
#373	ZNF70	4	13	17	461.308
#374	ZNF268	4	9	13	673.439
#375	SOX5	4	14	18	310.754
#376	NFAT5	4	10	14	792.522
#377	ZKSCAN5	4	6	10	200.664
#378	ZNF167	4	7	11	304.666
#379	SMAD1	4	6	10	66.195
#380	ETV6	4	11	15	582.551
#381	BTG2	4	16	20	385.707
#382	SIM1	4	15	19	1072.735
#383	TFDP1	4	9	13	532.015
#384	MAFB	4	13	17	224.448
#385	MECOM	4	11	15	382.046
#386	ZNF438	4	16	20	3803.468
#387	MSC	4	12	16	1806.141
#388	TEAD4	4	11	15	1048.743
#389	REL	4	10	14	519.69
#390	WT1	4	9	13	1810.766
#391	LHX2	4	7	11	469.284
#392	ZNF256	4	8	12	631.622
#393	FOXC1	4	8	12	1101.942
#394	MEF2D	4	8	12	1000.075
#395	TAF7	4	12	16	2569.221
#396	FOXP2	4	15	19	303.573
#397	SOX6	4	11	15	1089.381
#398	CUX2	4	18	22	1549.77
#399	HIC1	4	6	10	126.682
#400	TRIM29	4	12	16	1109.483
#401	ZBTB48	4	10	14	315.548
#402	FOSB	4	11	15	801.785
#403	C2orf3	4	16	20	1882.496
#404	C1orf85	4	13	17	418.397
#405	BATF	4	10	14	253.314
#406	SLC30A9	4	12	16	631.724
#407	DDIT3	3	11	14	911.518
#408	ARNT	3	13	16	435.073
#409	TGIF2	3	9	12	146.453
#410	CSRNP3	3	8	11	479.521
#411	DBP	3	15	18	284.428
#412	THRB	3	13	16	581.542
#413	ZHX2	3	9	12	968.666
#414	ZNF33A	3	11	14	840.3
#415	ZNF207	3	11	14	1426.663
#416	NPAS2	3	13	16	965.73
#417	PHTF1	3	10	13	304.276
#418	STAT5B	3	13	16	457.333
#419	SCAND1	3	13	16	942.944
#420	ARNT2	3	9	12	504.219
#421	MYNN	3	7	10	424.094
#422	GATA4	3	12	15	130.006
#423	HOXD10	3	10	13	886.279
#424	STAT3	3	11	14	621.468
#425	ST18	3	7	10	350.148
#426	ZFP90	3	18	21	440.871
#427	TAL1	3	8	11	536.615
#428	TAF5L	3	13	16	692.463
#429	VAV1	3	7	10	724.408
#430	NR1D2	3	17	20	963.776
#431	USF2	3	13	16	2237.279
#432	ELK4	3	12	15	993.074
#433	FOXA1	3	13	16	832.633
#434	HSF1	3	11	14	680.322
#435	TCF3	3	16	19	220.074
#436	CREB1	3	10	13	102.926
#437	HOXB7	3	9	12	355.551
#438	NR2F1	3	18	21	1569.077
#439	L3MBTL4	3	16	19	992.013
#440	GATAD2B	3	10	13	814.316
#441	CSRNP2	2	16	18	285.646
#442	ZXDC	2	12	14	400.019
#443	NFATC3	2	11	13	938.673
#444	BLZF1	2	17	19	1883.914
#445	NFX1	2	11	13	101.692
#446	PRDM2	2	16	18	5116.073
#447	TCF7L2	2	14	16	306.119
#448	ZNF232	2	9	11	400.324
#449	CTBP1	2	13	15	951.173
#450	PRRX1	2	13	15	532.225
#451	ZNF367	2	15	17	3666.108
#452	ETV5	2	11	13	2743.632
#453	RELB	2	15	17	425.321
#454	CREB3L4	2	13	15	842.411
#455	FOXQ1	2	14	16	392.222
#456	SP3	2	10	12	787.843
#457	ZNF187	2	15	17	233.119
#458	ALS2CR8	2	9	11	360.49
#459	MNT	2	15	17	981.605
#460	IRF5	2	8	10	415.839
#461	FOXO1	2	24	26	392.361
#462	FOSL1	2	9	11	63.567
#463	ATF6	2	9	11	159.651
#464	LASS6	2	13	15	360.901
#465	MEOX2	2	10	12	333.01
#466	ALX1	2	3	5	11.202
#467	STAT6	2	7	9	136.919
#468	ZNF274	1	9	10	99.943
#469	AFF4	1	9	10	68.541
#470	TWIST2	1	9	10	771.218
#471	SRF	1	13	14	47.305
#472	NANOG	1	11	12	27.309
#473	KLF5	1	14	15	68.462
#474	ZNF33B	1	14	15	271.143
#475	PPARG	1	15	16	700.96
#476	STRN3	1	13	14	39.33
#477	PKNOX1	1	10	11	199.077
#478	ETV7	1	9	10	90.75
#479	CREB5	1	13	14	688.41
#480	ZXDA	1	10	11	54.045
#481	ETV1	1	10	11	204.509
#482	SCAND3	1	13	14	1303.815
#483	ZIC1	1	16	17	612.991
#484	MYPOP	1	14	15	922.762
#485	MEIS1	1	9	10	636.914
#486	HOXC10	1	8	9	301.935
#487	LHX9	1	9	10	2826.482
#488	STAT4	1	16	17	632.82
#489	ZNF75D	1	13	14	225.133
#490	USF1	1	10	11	82.292
#491	SOX17	1	12	13	115.208
#492	FOXR1	0	5	5	0
#493	ADNP2	0	12	12	0
#494	TGIF1	0	14	14	0
#495	ESRRG	0	14	14	0
#496	HMBOX1	0	11	11	0
#497	ARNTL	0	17	17	0
#498	SPIC	0	10	10	0
#499	ASCL1	0	16	16	0
#500	VDR	0	16	16	0