Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TFAP4	67	0	67	0
#2	AFF1	66	5	71	1409.515
#3	REL	63	6	69	1921.061
#4	TLX2	62	4	66	245.247
#5	TP63	61	2	63	75.611
#6	USF2	60	8	68	830.555
#7	RUNX2	56	5	61	474.139
#8	ZNF192	56	10	66	1425.261
#9	ZNF157	46	12	58	920.179
#10	CREB3	46	9	55	2750.46
#11	MYF6	44	9	53	5183.927
#12	TRIM28	43	4	47	240.132
#13	IKZF3	43	9	52	1947.169
#14	TCF21	43	10	53	1562.584
#15	REXO4	43	4	47	83.978
#16	TCF25	43	3	46	586.529
#17	ZNF444	41	9	50	580.799
#18	ZXDC	40	6	46	256.635
#19	ARNTL2	39	11	50	1234.802
#20	RFXANK	39	9	48	820.803
#21	OLIG2	38	6	44	185.275
#22	GTF2H4	37	8	45	976.383
#23	MSC	37	15	52	2096.681
#24	NR2F6	36	9	45	1346.631
#25	DLX4	36	6	42	787.536
#26	PCGF2	36	12	48	1526.032
#27	GLI3	36	9	45	1945.845
#28	ZNF446	36	12	48	1059.035
#29	GAS7	35	5	40	1065.248
#30	HDAC1	35	12	47	1620.273
#31	RBCK1	35	12	47	1336.618
#32	ZEB2	34	5	39	783.002
#33	RUNX1	34	8	42	1383.116
#34	LHX1	34	8	42	184.394
#35	TBX6	32	11	43	1749.449
#36	YBX1	31	9	40	1163.158
#37	MEF2C	31	10	41	1214.194
#38	MYT1L	31	9	40	5579.391
#39	NFIC	30	6	36	4309.698
#40	TBR1	30	7	37	296.271
#41	HMGB1	30	11	41	863.423
#42	ZBTB17	29	9	38	1000.787
#43	HSF1	29	13	42	993.536
#44	TWIST1	28	8	36	1266.416
#45	JUNB	27	10	37	3865.176
#46	ZNF80	26	13	39	473.348
#47	NR4A1	26	11	37	1407.943
#48	TADA3	26	17	43	3535.561
#49	PDX1	26	11	37	406.542
#50	EDF1	25	9	34	312.839
#51	FOXO3	25	14	39	2438.648
#52	ENO1	25	17	42	2987.594
#53	MEIS2	25	9	34	911.464
#54	SNAPC2	25	11	36	902.049
#55	SUPT4H1	24	7	31	508.26
#56	NFATC3	24	15	39	404.973
#57	PURA	24	6	30	467.003
#58	TADA2A	24	12	36	1162.921
#59	SALL1	24	10	34	3890.303
#60	TBX3	23	13	36	1073.985
#61	PPARD	23	10	33	1590.744
#62	FOXA2	23	8	31	293.891
#63	TSC22D4	23	11	34	521.403
#64	NFKB2	23	6	29	68.176
#65	PPBPL2	23	8	31	355.765
#66	ZNF277	23	13	36	2901.173
#67	CBFA2T2	23	14	37	1387.451
#68	FLI1	23	5	28	1425.158
#69	HOXA5	23	7	30	755.742
#70	PHOX2B	22	8	30	1218.116
#71	ELF5	22	13	35	1084.539
#72	TFAM	22	9	31	880.971
#73	PLSCR1	22	13	35	1664.142
#74	VDR	22	11	33	1012.343
#75	TBX5	22	19	41	1006.201
#76	PHF1	22	19	41	1855.722
#77	HNF1A	22	12	34	3178.388
#78	NFE2L1	21	12	33	1243.615
#79	ESRRA	21	14	35	1319.136
#80	MECOM	21	11	32	2047.574
#81	HSF4	21	11	32	930.435
#82	FOXO1	21	13	34	710.674
#83	BTG2	21	10	31	237.506
#84	TFEB	21	12	33	3186.905
#85	MEOX1	21	1	22	16.789
#86	MEOX2	21	8	29	1071.708
#87	ALX3	21	14	35	2930.64
#88	POU3F1	20	13	33	392.431
#89	IRX5	20	8	28	893.571
#90	POU2F2	20	11	31	889.971
#91	FOXD2	20	15	35	3525.734
#92	E2F6	20	13	33	1362.326
#93	MZF1	20	12	32	380.535
#94	GATA6	19	12	31	1004.259
#95	TFE3	19	13	32	997.726
#96	GBX2	19	8	27	2090.343
#97	BATF3	19	15	34	2759.892
#98	ZNF174	19	13	32	725.68
#99	YEATS4	19	16	35	2883.104
#100	TCF4	19	10	29	1295.143
#101	BNC1	19	8	27	1165.917
#102	ZBTB48	19	12	31	217.826
#103	HOXA9	19	15	34	1939.758
#104	HOXC5	19	12	31	2140.845
#105	ADNP2	18	12	30	1376.4
#106	TSHZ2	18	12	30	687.786
#107	BCL6	18	8	26	127.357
#108	SLC2A4RG	18	16	34	726.326
#109	AEBP1	18	16	34	1987.859
#110	TCF3	18	14	32	654.882
#111	IRF3	18	14	32	2606.883
#112	NKX2-5	18	12	30	2779.267
#113	ZFPM2	18	7	25	422.713
#114	ZNF394	18	6	24	280.822
#115	ONECUT2	18	16	34	496.263
#116	SMAD1	18	15	33	1570.096
#117	MSX1	18	10	28	2185.335
#118	IRF4	18	11	29	597.706
#119	NR5A1	18	15	33	2569.869
#120	BACH1	18	11	29	1076.139
#121	MYOD1	17	12	29	331.568
#122	MSRB2	17	12	29	4929.613
#123	FOXA1	17	12	29	1674.576
#124	EPAS1	17	8	25	558.73
#125	VTN	17	12	29	212.33
#126	SNAPC5	17	10	27	2512.38
#127	HMG20B	17	6	23	318.266
#128	HSF2	17	16	33	1632.751
#129	PRRX2	17	13	30	7489.506
#130	OVOL1	17	11	28	519.984
#131	MAFB	17	8	25	618.472
#132	TFAP2A	17	13	30	2030.046
#133	LASS6	17	20	37	1093.056
#134	MAFK	16	14	30	1574.109
#135	PBX2	16	11	27	391.85
#136	MBD1	16	14	30	3385.288
#137	PRDM2	16	10	26	425.253
#138	ELF1	16	15	31	1621.93
#139	ZNF133	16	14	30	1765.819
#140	POU6F1	16	15	31	2152.466
#141	KLF2	16	11	27	379.526
#142	NR1I2	16	14	30	6203.367
#143	ESR2	16	7	23	1587.332
#144	NR2C1	16	15	31	1701.523
#145	PRDM1	16	15	31	394.828
#146	PKNOX1	16	14	30	807.331
#147	PAX4	16	8	24	1230.596
#148	FOXN3	16	16	32	740.885
#149	STAT3	16	16	32	2363.488
#150	ELF2	16	15	31	1990.379
#151	BLZF1	16	9	25	1651.496
#152	LHX2	15	12	27	499.396
#153	RUNX1T1	15	11	26	614.55
#154	ECSIT	15	13	28	1154.946
#155	CRX	15	19	34	1653.353
#156	CTBP1	15	7	22	646.171
#157	E2F3	15	8	23	515.033
#158	GATA2	15	20	35	1780.253
#159	MLL	15	15	30	1272.938
#160	SUPT6H	15	12	27	562.192
#161	HMX1	15	9	24	291.645
#162	SOX4	15	11	26	1123.635
#163	GATAD1	15	15	30	1371.873
#164	TSC22D3	15	9	24	102.019
#165	BCL3	15	12	27	1839.45
#166	AHR	15	5	20	171.26
#167	SNAI2	15	7	22	388.483
#168	ZSCAN2	15	15	30	674.735
#169	ZNF91	15	11	26	859.616
#170	CUX1	14	12	26	1327.463
#171	POU6F2	14	14	28	1985.826
#172	SPDEF	14	15	29	2365.053
#173	ATF6	14	13	27	1483.472
#174	TSC22D2	14	15	29	2542.704
#175	HOXD1	14	12	26	859.571
#176	IRF8	14	10	24	630.65
#177	AR	14	13	27	1369.565
#178	LHX6	14	11	25	1220.06
#179	ZNF219	14	15	29	1723.403
#180	SIM1	14	15	29	564.597
#181	ZNF268	14	10	24	895.783
#182	ZSCAN12	14	11	25	1251.226
#183	ZGPAT	14	13	27	363.134
#184	TP53	13	14	27	1450.403
#185	YY1	13	9	22	223.142
#186	SREBF1	13	15	28	1421.063
#187	CITED1	13	10	23	1218.838
#188	SOX18	13	14	27	737.504
#189	NOTCH1	13	14	27	2788.312
#190	ZHX2	13	15	28	2348.747
#191	ELK1	13	13	26	414.981
#192	SATB1	13	16	29	1154.632
#193	HOXA7	13	12	25	2212.596
#194	ZNF217	13	11	24	558.537
#195	HOPX	13	17	30	1682.911
#196	ZNF41	13	13	26	1607.561
#197	ZNF117	13	11	24	455.285
#198	ZFHX3	13	10	23	369.34
#199	HNF4A	13	17	30	1709.071
#200	JUN	13	10	23	509.267
#201	E2F2	13	13	26	1693.883
#202	BHLHE41	13	9	22	645.959
#203	NR2F1	13	16	29	3263.565
#204	GATA3	12	9	21	371.207
#205	EHF	12	14	26	1244.466
#206	IRF6	12	18	30	1636.997
#207	HMGB2	12	11	23	508.394
#208	HMGA1	12	8	20	929.698
#209	PPARA	12	16	28	411.473
#210	FUBP1	12	16	28	2708.249
#211	RFX5	12	17	29	1555.642
#212	SIM2	12	13	25	1067.577
#213	SIX2	12	20	32	1720.029
#214	FOXE1	12	17	29	1860.058
#215	FOSL2	12	16	28	1574.518
#216	ZNF238	12	21	33	3104.569
#217	CREB3L1	12	14	26	1069.24
#218	ZNF140	12	10	22	557.048
#219	RORA	12	12	24	2849.213
#220	HLF	12	13	25	504.055
#221	TLX3	12	13	25	1618.621
#222	NR1I3	12	15	27	1035.167
#223	NR2F2	12	17	29	5201.942
#224	WT1	12	16	28	1586
#225	GABPA	12	13	25	695.558
#226	E2F5	11	14	25	1412.513
#227	SLC26A3	11	16	27	5713.259
#228	ZNF165	11	23	34	1058.305
#229	DLX2	11	14	25	3032.204
#230	CSDA	11	20	31	1075.785
#231	POU1F1	11	13	24	343.859
#232	TCF7L2	11	17	28	859.761
#233	KLF6	11	11	22	433.721
#234	ETV5	11	14	25	402.419
#235	DMRT1	11	14	25	1851.063
#236	HOXA10	11	15	26	977.446
#237	BARX1	11	15	26	507.337
#238	HOXB7	11	16	27	1339.167
#239	NFATC1	11	13	24	904.301
#240	TAF1B	11	14	25	3655.421
#241	FBXW7	11	19	30	1592.206
#242	RXRB	11	12	23	2058.43
#243	TAF12	10	18	28	1828.527
#244	NR4A2	10	18	28	1285.946
#245	SIX3	10	19	29	1155.355
#246	C2orf3	10	19	29	862.134
#247	SCRT1	10	18	28	679.193
#248	MAX	10	16	26	2026.238
#249	FOXD3	10	12	22	2082.626
#250	BHLHE40	10	11	21	716.947
#251	HOXC10	10	12	22	1193.583
#252	MLXIPL	10	12	22	1905.368
#253	ZNF132	10	11	21	1037.761
#254	ARNT2	10	14	24	1068.951
#255	SOX2	10	19	29	3253.748
#256	POU4F3	10	13	23	782.959
#257	HEY1	10	15	25	1132.384
#258	FOXJ1	10	12	22	1142.547
#259	EMX1	10	13	23	1124.749
#260	HMBOX1	10	15	25	1382.154
#261	ZFP37	10	15	25	575.532
#262	ZNF131	10	13	23	550.23
#263	HOXD3	10	16	26	741.962
#264	ZNF187	10	14	24	2194.534
#265	KLF9	10	16	26	715.083
#266	ZNF135	10	16	26	794.243
#267	HOXC8	9	14	23	1122.27
#268	RUNX3	9	16	25	999.418
#269	RARG	9	15	24	958.587
#270	ZFP36L1	9	15	24	1475.757
#271	DBP	9	13	22	559.749
#272	ZNF155	9	14	23	1617.535
#273	HCFC1	9	13	22	917.037
#274	NEUROG1	9	12	21	1296.583
#275	CREBZF	9	17	26	604.968
#276	PEG3	9	14	23	1276.461
#277	PPARG	9	15	24	876.948
#278	E2F8	9	14	23	962.094
#279	FOS	9	17	26	975.583
#280	MYBL2	9	14	23	1103.344
#281	LEF1	9	13	22	963.633
#282	JUND	9	11	20	647.914
#283	MMP14	9	4	13	416.162
#284	ZNF93	9	18	27	1411.745
#285	SOX9	9	15	24	1137.9
#286	MYC	9	17	26	1145.988
#287	TBX2	9	18	27	650.173
#288	PKNOX2	9	17	26	1224.72
#289	NFE2L3	9	14	23	884.435
#290	HOXB6	9	13	22	1132.085
#291	ATF6B	9	17	26	432.07
#292	MAF	9	17	26	1166.816
#293	ZNF236	9	16	25	1506.487
#294	SCAND2	9	9	18	126.918
#295	SIX1	9	17	26	1894.23
#296	RARA	8	19	27	1300.694
#297	ZNF202	8	16	24	549.424
#298	SMAD5	8	12	20	578.041
#299	ASCL1	8	18	26	940.157
#300	HOXA1	8	11	19	727.614
#301	HEY2	8	13	21	861.877
#302	POU4F1	8	14	22	449.796
#303	HOXA11	8	11	19	1452.248
#304	IRF5	8	14	22	650.596
#305	FOXP3	8	17	25	2273.934
#306	ESRRG	8	16	24	1504.896
#307	PAX3	8	14	22	1529.704
#308	ZNF75D	8	14	22	1078.176
#309	SMAD6	8	21	29	1424.865
#310	RARB	8	13	21	478.213
#311	SMAD3	8	17	25	1618.086
#312	SATB2	8	14	22	1525.76
#313	MSX2	8	16	24	3118.017
#314	MLLT10	8	9	17	511.14
#315	VSX1	8	11	19	1499.512
#316	SCML1	8	15	23	794.268
#317	LMO4	8	11	19	200.5
#318	PROX1	8	15	23	919.735
#319	GTF2I	8	15	23	1043.593
#320	HOXA2	8	16	24	939.801
#321	RCAN1	8	12	20	1016.816
#322	NR6A1	8	13	21	3170.85
#323	CTNNB1	8	11	19	1051.543
#324	ZNF154	8	13	21	175.281
#325	HOXC13	8	12	20	1041.075
#326	STAT2	8	17	25	912.845
#327	BRD8	8	17	25	847.447
#328	MAFF	8	14	22	1134.042
#329	REST	8	13	21	509.607
#330	VAV1	8	12	20	642.54
#331	SOX13	7	14	21	575.698
#332	SPI1	7	11	18	810.599
#333	NFYC	7	15	22	1135.074
#334	RERE	7	14	21	1125.44
#335	ELF4	7	20	27	913.516
#336	NR4A3	7	16	23	500.262
#337	ZNF3	7	16	23	1593.219
#338	HOXD11	7	19	26	1815.375
#339	ZNF500	7	15	22	1582.316
#340	NPAT	7	15	22	757.527
#341	PITX2	7	19	26	2601.793
#342	WNT5A	7	13	20	728.559
#343	EN2	7	13	20	852.507
#344	TEAD4	7	12	19	878.672
#345	SPIB	7	14	21	1380.944
#346	TFDP2	7	10	17	277.278
#347	NKX3-1	7	15	22	1247.574
#348	SOX10	7	15	22	607.051
#349	CSRNP3	7	16	23	736.285
#350	ZNF639	7	14	21	1437.002
#351	KLF5	7	10	17	664.911
#352	HESX1	7	15	22	997.769
#353	GCM1	7	14	21	399.43
#354	TCF15	7	11	18	985.182
#355	HOXB2	7	11	18	509.145
#356	NFYB	7	12	19	582.802
#357	ELK4	7	16	23	1306.083
#358	SIX5	7	19	26	601.947
#359	EGR4	7	15	22	426.814
#360	SP1	7	20	27	1283.212
#361	GTF2H3	7	13	20	155.063
#362	TLX1	7	15	22	2056.898
#363	ETV1	7	13	20	619.064
#364	MYT1	7	20	27	1830.515
#365	NFIX	7	14	21	1637.358
#366	CEBPE	7	11	18	1189.907
#367	LMX1B	7	13	20	1132.703
#368	NFIB	7	17	24	1031.822
#369	TFEC	7	11	18	521.346
#370	MNX1	7	20	27	939.938
#371	ZNF323	7	17	24	1413.325
#372	MYCN	6	16	22	761.174
#373	ETV2	6	14	20	1023.792
#374	HOXD13	6	9	15	696.251
#375	TP73	6	10	16	885.014
#376	TFAP2C	6	11	17	995.44
#377	ZNF134	6	18	24	986.183
#378	EVX1	6	19	25	888.473
#379	TAF13	6	16	22	1108.296
#380	ONECUT1	6	18	24	3395.314
#381	KDM5B	6	16	22	2104.085
#382	NFYA	6	17	23	937.924
#383	ZNF45	6	14	20	544.867
#384	HNF4G	6	10	16	435.066
#385	PAX8	6	15	21	1155.618
#386	MEF2A	6	13	19	504.513
#387	RELA	6	16	22	1083.988
#388	NKX2-1	6	13	19	496.309
#389	TCEAL1	6	17	23	493.821
#390	SRY	6	12	18	633.818
#391	CEBPB	6	14	20	1755.239
#392	PGR	6	16	22	1649.061
#393	RB1	6	14	20	1612.445
#394	NPAS2	6	21	27	854.812
#395	CITED2	6	18	24	853.355
#396	IKZF1	6	16	22	601.09
#397	ZNF167	6	21	27	2035.12
#398	EGR3	6	10	16	1463.479
#399	FOXI1	6	18	24	515.355
#400	NKX2-8	6	12	18	609.357
#401	ZSCAN18	6	11	17	453.573
#402	PITX1	6	13	19	421.461
#403	NR0B1	6	16	22	1216.249
#404	GABPB1	6	13	19	970.077
#405	EN1	6	14	20	1777.667
#406	CREB1	6	16	22	845.995
#407	ZNF81	6	16	22	545.227
#408	NR3C2	6	19	25	719.421
#409	TBX19	6	16	22	963.219
#410	FOSB	6	10	16	1304.06
#411	KLF4	5	19	24	710.912
#412	ZNF643	5	12	17	847.891
#413	E2F4	5	13	18	760.543
#414	FOXH1	5	18	23	567.076
#415	SOX30	5	17	22	959.541
#416	STAT1	5	14	19	396.171
#417	BATF	5	15	20	692.482
#418	TAL1	5	16	21	388.291
#419	PAX6	5	19	24	878.602
#420	HOXD9	5	11	16	470.129
#421	NFX1	5	16	21	1018.314
#422	CEBPD	5	14	19	1176.908
#423	T	5	19	24	1061.055
#424	PTH	5	17	22	1264.282
#425	FOXO4	5	9	14	840.429
#426	CBFB	5	10	15	426.995
#427	ATF5	5	10	15	337.117
#428	TFCP2	5	15	20	477.491
#429	ZBTB25	5	17	22	773.569
#430	TFAP2B	5	25	30	1643.017
#431	ESR1	5	17	22	854.844
#432	PBX1	5	29	34	1753.576
#433	POU2F3	5	16	21	383.133
#434	HOXB8	5	15	20	738.476
#435	ZNF24	5	13	18	484.249
#436	HEYL	5	13	18	826.185
#437	HES1	5	11	16	785.839
#438	GLI2	5	14	19	526.974
#439	HOXD4	5	22	27	1247.968
#440	RELB	4	14	18	163
#441	SOX11	4	14	18	1067.654
#442	MEF2D	4	17	21	914.39
#443	MYCL1	4	11	15	231.577
#444	RXRG	4	19	23	715.67
#445	CDKN2A	4	16	20	1275.794
#446	STRN3	4	11	15	359.696
#447	MYF5	4	17	21	741.061
#448	POU5F1B	4	11	15	346.146
#449	HOXB9	4	18	22	706.283
#450	FOSL1	4	21	25	1346.329
#451	ARNTL	4	11	15	401.698
#452	ISL1	4	17	21	1308.492
#453	FOXD1	4	19	23	850.464
#454	CREM	4	11	15	525.789
#455	HDAC2	4	12	16	206.547
#456	C11orf9	4	16	20	696.369
#457	FOXB1	4	12	16	430.721
#458	NFAT5	4	17	21	435.671
#459	NPAS1	4	20	24	821.151
#460	THRA	4	17	21	738.514
#461	NR1H4	3	18	21	935.912
#462	ZFP36L2	3	17	20	150.367
#463	TCF12	3	16	19	428.609
#464	ZEB1	3	21	24	267.96
#465	TRIM29	3	13	16	268.664
#466	VENTX	3	13	16	458.355
#467	HIF3A	3	13	16	149.99
#468	LZTS1	3	21	24	248.944
#469	NKX3-2	3	14	17	252.717
#470	KLF12	3	16	19	1883.548
#471	ZIC3	3	14	17	152.606
#472	CBL	3	17	20	397.243
#473	NFATC4	3	15	18	433.542
#474	FOXM1	3	18	21	382.319
#475	E2F1	3	17	20	2488.505
#476	CREBBP	3	16	19	949.19
#477	ST18	3	14	17	228.032
#478	GSC2	3	14	17	376.889
#479	ETV6	2	12	14	245.905
#480	KLF15	2	12	14	69.007
#481	IRX4	2	16	18	239.706
#482	PLAG1	2	15	17	239.581
#483	RORC	2	19	21	1547.872
#484	TCF7	2	16	18	509.909
#485	HIRA	2	21	23	714.57
#486	ZIC1	2	20	22	248.642
#487	POU3F4	2	15	17	496.104
#488	NR5A2	2	11	13	150.779
#489	GATA4	1	15	16	215.592
#490	SRF	1	21	22	275.361
#491	TFDP1	1	16	17	408.76
#492	CREB5	1	14	15	71.71
#493	TBX1	1	12	13	82.461
#494	ZNF287	1	19	20	43.706
#495	TEF	1	15	16	161.109
#496	CUX2	1	19	20	254.006
#497	ALS2CR8	1	16	17	146.193
#498	NFE2	0	15	15	0
#499	ETV4	0	12	12	0
#500	MGA	0	15	15	0