Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ENO1	46	3	49	1595.631
#2	BHLHE40	43	2	45	220.485
#3	FOXA1	40	0	40	0
#4	FOXC1	35	2	37	329.529
#5	YBX1	34	3	37	1870.132
#6	NFYC	32	2	34	30.98
#7	MYC	31	7	38	1119.815
#8	EN1	30	5	35	113.397
#9	RELA	30	4	34	293.986
#10	DRAP1	30	5	35	1237.26
#11	BCL3	28	14	42	1861.7
#12	XBP1	28	4	32	696.002
#13	ZFP36L2	28	3	31	55.896
#14	STAT3	28	5	33	182.779
#15	FOXM1	27	5	32	622.17
#16	MAX	27	5	32	245.821
#17	AR	27	4	31	264.647
#18	TFAP2B	27	11	38	2185.408
#19	BATF	26	12	38	2497.927
#20	CBFB	25	10	35	854.755
#21	CEBPB	24	7	31	504.163
#22	PRRX1	24	8	32	408.147
#23	TCF3	23	10	33	1563.829
#24	CSDA	23	10	33	2077.419
#25	E2F8	23	9	32	2843.218
#26	MMP14	23	8	31	376.111
#27	FOS	23	9	32	1525.904
#28	TFCP2L1	22	7	29	901.659
#29	KLF5	22	7	29	723.274
#30	HOXB2	22	7	29	721.29
#31	GTF2I	22	8	30	845.837
#32	CBFA2T3	22	7	29	1174.236
#33	SPDEF	22	3	25	301.419
#34	SNAI2	22	7	29	1046.247
#35	SUPT6H	21	11	32	2061.12
#36	ERF	21	7	28	494.547
#37	RXRB	21	8	29	750.592
#38	OVOL1	20	10	30	1229.885
#39	KLF6	20	8	28	850.714
#40	ZKSCAN1	20	7	27	1346.536
#41	AFF4	20	4	24	1082.317
#42	ZEB2	19	3	22	490.167
#43	LMO4	19	10	29	2157.078
#44	EPAS1	19	9	28	851.977
#45	TCF4	19	8	27	1028.741
#46	TCF7L1	19	11	30	804.783
#47	MAF	18	7	25	1311.752
#48	JUND	18	9	27	1009.158
#49	MECOM	18	12	30	2474.447
#50	TFDP1	18	12	30	815.276
#51	NFE2L3	18	12	30	1358.262
#52	CDKN2A	18	10	28	513.867
#53	HIRA	18	8	26	1871.937
#54	E2F3	18	9	27	1172.222
#55	ARNT	18	14	32	733.194
#56	GATA2	18	7	25	320.032
#57	ZNF148	18	6	24	329.529
#58	GATA3	17	12	29	3074.435
#59	RARA	17	14	31	1555.128
#60	NKX2-1	17	6	23	820.281
#61	ELF3	17	7	24	1614.924
#62	SUPT4H1	17	10	27	927.258
#63	IRF7	17	14	31	1591.625
#64	GLI2	17	12	29	2111.865
#65	KLF4	17	14	31	2341.498
#66	ZNF238	17	13	30	2129.608
#67	ARNTL2	17	11	28	1953.402
#68	NR2F1	17	10	27	1564.896
#69	CUX2	17	10	27	1379.893
#70	TEAD4	16	9	25	821.741
#71	REXO4	16	6	22	1557.622
#72	ZFHX4	16	8	24	1147.23
#73	FUBP1	16	9	25	1175.953
#74	RUNX1	16	12	28	1845.425
#75	ZNF323	16	9	25	2206.068
#76	HOXC10	16	13	29	1141.058
#77	SMAD3	16	11	27	1778.766
#78	HOXA4	16	11	27	1949.314
#79	FOXA2	16	8	24	1362.349
#80	BRD8	16	10	26	2183.2
#81	HOXA10	16	10	26	1729.152
#82	SLC26A3	16	9	25	1124.8
#83	BCL11B	16	10	26	1279.904
#84	AEBP1	16	11	27	1013.857
#85	ZNF45	16	9	25	1987.451
#86	STAT1	16	7	23	643.297
#87	FOXO3	16	11	27	1395.094
#88	C2orf3	15	6	21	460.379
#89	GAS7	15	16	31	1684.295
#90	ELF1	15	5	20	585.813
#91	CTNNB1	15	9	24	998.19
#92	ZNF91	15	10	25	1052.095
#93	IRF8	15	10	25	1077.997
#94	DBP	15	15	30	2504.098
#95	MTA2	15	8	23	2142.59
#96	PAX5	15	6	21	944.245
#97	PAX6	15	14	29	2814.718
#98	ESR1	15	9	24	338.613
#99	MYT1	15	10	25	1684.272
#100	MEOX1	15	10	25	1025.037
#101	PKNOX1	15	11	26	1726.243
#102	ETV1	15	17	32	3132.559
#103	NFATC1	15	11	26	3208.153
#104	MYF6	15	8	23	1073.37
#105	ZEB1	15	12	27	1407.088
#106	TFAP2C	15	12	27	1660.956
#107	PBX1	14	16	30	1682.381
#108	ELK4	14	12	26	1709.669
#109	RORC	14	13	27	1714.585
#110	FLI1	14	11	25	911.064
#111	ALX1	14	7	21	900.365
#112	NR2E3	14	9	23	2097.951
#113	SOX10	14	11	25	661.405
#114	FOXN3	14	9	23	969.739
#115	SOX9	14	12	26	1533.349
#116	PPARA	14	11	25	1651.908
#117	ZNF155	14	13	27	1273.169
#118	NR2F6	14	10	24	1708.019
#119	HMG20B	14	12	26	790.451
#120	NPAT	13	11	24	1370.431
#121	THRA	13	11	24	1286.834
#122	TSHZ2	13	8	21	1128.153
#123	VTN	13	5	18	633.013
#124	STAT6	13	14	27	1764.009
#125	TFAP2A	13	11	24	1244.279
#126	JUN	13	11	24	1113.36
#127	ZNF444	13	14	27	1020.635
#128	ALS2CR8	13	8	21	1149.057
#129	RERE	13	12	25	1532.862
#130	ZNF236	13	10	23	1796.13
#131	EGR1	13	6	19	832.795
#132	HSF2	13	11	24	1758.035
#133	HOPX	13	13	26	953.401
#134	ZNF134	13	13	26	1932.915
#135	TBR1	13	10	23	1444.115
#136	ZFPM2	13	10	23	1022.004
#137	SOX2	13	8	21	865.295
#138	MAFF	13	11	24	1783.364
#139	TAF12	13	11	24	1503.769
#140	MXD1	13	11	24	1950.466
#141	TWIST1	13	12	25	1401.006
#142	ZNF192	13	9	22	962.436
#143	VSX1	13	7	20	1302.204
#144	MAFB	13	11	24	2071.855
#145	HEY2	13	12	25	1327.177
#146	TRPS1	13	9	22	1228.48
#147	VAX2	13	7	20	1238.083
#148	SOX13	13	6	19	615.902
#149	HOXC13	13	15	28	2519.362
#150	KLF9	12	5	17	415.587
#151	TP53	12	15	27	1318.066
#152	MSX2	12	15	27	973.017
#153	RUNX1T1	12	14	26	1518.15
#154	GATA6	12	10	22	1395.956
#155	HOXA9	12	10	22	1193.905
#156	ZNF117	12	7	19	937.007
#157	ARNTL	12	11	23	1226.075
#158	GABPA	12	13	25	1118.748
#159	RB1	12	10	22	1232.715
#160	ZNF639	12	10	22	1249.102
#161	NR5A1	12	10	22	1342.73
#162	SOX4	12	11	23	922.038
#163	OLIG2	12	11	23	1943.644
#164	BHLHE41	12	7	19	1122.798
#165	NR1H4	12	13	25	1437.265
#166	HOXD4	12	11	23	772.592
#167	MYCL1	12	7	19	617.076
#168	SP140	12	8	20	1519.826
#169	FOXE3	12	11	23	1584.333
#170	ELK3	12	9	21	613.539
#171	TLX1	12	8	20	1515.787
#172	HOXA5	12	2	14	332.641
#173	FOXD3	12	9	21	1228.893
#174	TFE3	12	10	22	1022.423
#175	BCL6	12	13	25	1051.75
#176	SLC2A4RG	12	6	18	675.7
#177	TFEC	12	7	19	1061.746
#178	HOXD9	11	13	24	1815.569
#179	CEBPE	11	9	20	846.835
#180	HCLS1	11	8	19	910.435
#181	GATA4	11	9	20	1157.757
#182	HOXD13	11	10	21	1325.365
#183	ZNF75D	11	11	22	1936.686
#184	TSC22D3	11	14	25	1167.332
#185	MLLT10	11	13	24	1411.654
#186	ZNF81	11	13	24	1822.586
#187	NFIX	11	8	19	1241.851
#188	ZNF434	11	11	22	1569.475
#189	SPIB	11	12	23	889.437
#190	NPAS2	11	11	22	1355.909
#191	ARNT2	11	11	22	1580.826
#192	SCML1	11	15	26	1690.407
#193	ZNF394	11	8	19	1116.94
#194	SIX2	11	10	21	1407.381
#195	MEF2A	11	8	19	850.792
#196	LHX2	11	15	26	1698.172
#197	POU6F1	11	11	22	1898.845
#198	E2F5	11	12	23	1773.198
#199	USF2	11	7	18	895.712
#200	TCF12	11	11	22	853.936
#201	ESRRA	11	11	22	651.78
#202	HOXC8	11	15	26	1654.52
#203	LASS6	10	12	22	1317.388
#204	CREB3L1	10	15	25	1844.148
#205	FOXD1	10	10	20	1027.388
#206	NR3C2	10	15	25	1379.392
#207	NR2E1	10	13	23	992.987
#208	EGR4	10	14	24	1318.174
#209	HOXA7	10	12	22	1468.733
#210	EGR2	10	6	16	846.827
#211	E2F1	10	14	24	700.928
#212	MYBL2	10	6	16	528.167
#213	PCGF2	10	12	22	1310.856
#214	HINFP	10	8	18	786.028
#215	HOXB7	10	13	23	1359.695
#216	CREM	10	9	19	1058.007
#217	NKX3-2	10	13	23	1099.983
#218	ZNF165	10	15	25	1849.613
#219	HIC1	10	12	22	867.734
#220	PHOX2B	10	11	21	1390.589
#221	NR2C1	10	16	26	1613.18
#222	HLF	10	10	20	975.395
#223	MSL3	10	6	16	383.952
#224	SATB2	10	14	24	1330.676
#225	MEF2D	10	11	21	1154.161
#226	RORA	10	7	17	575.511
#227	ETV5	10	10	20	586.088
#228	SOX18	10	9	19	829.876
#229	POU3F4	10	15	25	1599.559
#230	ERG	10	10	20	2062.837
#231	ASCL2	10	9	19	1467.763
#232	SREBF1	10	9	19	742.732
#233	TADA3	10	5	15	673.82
#234	PLSCR1	10	11	21	729.255
#235	HOXD11	10	8	18	573.292
#236	ISL1	10	14	24	1298.445
#237	SNAPC4	10	13	23	1518.398
#238	HOXB1	10	8	18	691.53
#239	ZXDC	10	14	24	1706.15
#240	ZNF24	10	11	21	390.596
#241	FOXB1	10	8	18	1068.335
#242	HSF1	10	11	21	991.453
#243	IRX5	10	11	21	1803.421
#244	POU5F1B	9	12	21	992.164
#245	HOXA11	9	8	17	797.808
#246	TBX2	9	12	21	1017.853
#247	ELF5	9	13	22	1255.989
#248	NR4A1	9	11	20	1214.211
#249	FOXC2	9	11	20	906.436
#250	RARB	9	12	21	461.336
#251	CITED2	9	14	23	1117.684
#252	BTG2	9	14	23	1167.087
#253	PAX3	9	11	20	949.386
#254	KLF12	9	9	18	1265.955
#255	MLL	9	14	23	1543.357
#256	MYT1L	9	9	18	1201.005
#257	HR	9	9	18	1448.979
#258	RUNX3	9	13	22	1133.209
#259	LEF1	9	8	17	1061.506
#260	RARG	9	9	18	775.762
#261	PPARG	9	10	19	994.38
#262	DMRT1	9	12	21	1249.311
#263	SOX5	9	8	17	1470.921
#264	IKZF1	9	10	19	1753.25
#265	TLX2	9	11	20	1002.752
#266	SOX21	9	12	21	1476.422
#267	CITED1	9	11	20	961.217
#268	SMAD4	9	9	18	1507.228
#269	TBX19	9	14	23	691.504
#270	TFEB	9	10	19	1855.676
#271	ZSCAN2	9	11	20	1237.153
#272	NFYA	9	12	21	1065.99
#273	CREBBP	9	10	19	726.349
#274	YY1	9	7	16	526.169
#275	ATF3	9	10	19	1064.859
#276	NFYB	9	6	15	332.998
#277	PEG3	9	10	19	931.151
#278	MSC	9	8	17	669.42
#279	HOXB3	9	9	18	1076.594
#280	NFATC3	9	9	18	764.308
#281	TBX1	9	11	20	1691.121
#282	AHR	9	12	21	1322.631
#283	HAND1	9	10	19	883.253
#284	TBX10	9	9	18	634.348
#285	SIX3	9	12	21	1051.908
#286	HDAC2	9	10	19	618.251
#287	DLX2	9	15	24	1637.222
#288	CEBPD	9	9	18	832.232
#289	POU2F3	9	14	23	638.847
#290	VENTX	9	15	24	1121.319
#291	ZNF202	9	13	22	1176.744
#292	ELF4	9	16	25	1528.721
#293	ST18	9	9	18	1609.875
#294	TCF7L2	8	8	16	402.293
#295	NR4A3	8	12	20	747.222
#296	SRY	8	13	21	1527.946
#297	TBX3	8	13	21	1294.409
#298	SCRT1	8	11	19	911.546
#299	SMAD5	8	8	16	802.544
#300	ZNF174	8	16	24	1139.536
#301	CEBPA	8	10	18	2435.926
#302	ATF6	8	13	21	1089.873
#303	HOXB9	8	12	20	975.114
#304	MTF1	8	9	17	580.205
#305	ONECUT1	8	11	19	1148.65
#306	FOXD2	8	11	19	1215.348
#307	EHF	8	13	21	1073.551
#308	NFIB	8	14	22	937
#309	EVX1	8	8	16	357.241
#310	PLAG1	8	15	23	1576.979
#311	HOXB6	8	14	22	1113.044
#312	PITX2	8	9	17	860.86
#313	TAL1	8	9	17	928.248
#314	AFF1	8	10	18	952.403
#315	PKNOX2	8	12	20	1148.733
#316	HOXD3	8	12	20	1570.717
#317	T	8	9	17	811.898
#318	RBPJL	8	11	19	564.585
#319	STAT2	8	13	21	629.338
#320	POU4F3	8	8	16	665.028
#321	FOXJ1	8	14	22	695.552
#322	SIM1	8	13	21	1082.728
#323	HIF3A	8	10	18	738.252
#324	NR2F2	8	9	17	1400.871
#325	HMGA1	8	16	24	1286.603
#326	NPAS1	8	12	20	1437.174
#327	PTH	8	13	21	1320.234
#328	POU2F2	8	14	22	1731.813
#329	POU1F1	8	15	23	2006.927
#330	ZNF132	8	6	14	784.703
#331	FOXO4	8	15	23	1145.603
#332	TCF15	8	8	16	855.635
#333	HOXA2	8	11	19	1146.165
#334	GATA1	8	9	17	1171.611
#335	NFE2	8	10	18	882.408
#336	PHF1	8	10	18	911.416
#337	TLX3	8	11	19	735.966
#338	PRDM1	8	13	21	1142.65
#339	ATOH1	7	8	15	590.298
#340	ZSCAN18	7	7	14	389.216
#341	E2F2	7	9	16	848.247
#342	SMAD6	7	13	20	1273.558
#343	ESR2	7	15	22	927.294
#344	NFKB2	7	15	22	1301.544
#345	ARID3A	7	13	20	1016.832
#346	TADA2A	7	8	15	684.053
#347	SMAD1	7	14	21	994.84
#348	ZNF135	7	15	22	1557.154
#349	PITX1	7	10	17	671.977
#350	TCF7	7	7	14	500.204
#351	BARX1	7	14	21	866.805
#352	LHX1	7	8	15	763.031
#353	ESRRG	7	15	22	1056.202
#354	CTBP1	7	12	19	1656.223
#355	ATF6B	7	14	21	1378.951
#356	SPI1	7	12	19	1187.337
#357	ZBTB25	7	10	17	708.789
#358	NR4A2	7	15	22	862.308
#359	TBX6	7	10	17	483.023
#360	ZNF167	7	12	19	834.601
#361	HOXC5	7	14	21	648.658
#362	SRF	7	10	17	618.296
#363	MEF2C	7	13	20	939.588
#364	NR5A2	7	18	25	1738.139
#365	MNX1	7	12	19	860.86
#366	ZNF80	7	11	18	784.05
#367	SIM2	7	21	28	1753.014
#368	LZTS1	7	10	17	793.764
#369	EGR3	7	12	19	1096.192
#370	RCAN1	7	15	22	1497.331
#371	FOXI1	7	10	17	665.539
#372	REST	7	14	21	685.719
#373	ZIC3	7	8	15	793.468
#374	PAX4	7	10	17	760.938
#375	NFAT5	7	16	23	1086.207
#376	PDX1	7	11	18	568.409
#377	HNF1A	7	13	20	1069.951
#378	FOXP3	6	13	19	604.949
#379	ZFP36L1	6	15	21	1035.219
#380	SIX1	6	8	14	643.961
#381	NKX6-1	6	11	17	1140.864
#382	GBX2	6	13	19	688.863
#383	POU4F1	6	11	17	762.343
#384	BNC1	6	11	17	875.82
#385	HNF4G	6	13	19	1669.133
#386	EN2	6	14	20	1035.774
#387	TFAP4	6	7	13	881.186
#388	MAFK	6	16	22	1106.876
#389	NR0B1	6	14	20	1096.151
#390	CRX	6	14	20	853.679
#391	RAX	6	11	17	626.252
#392	HNF4A	6	12	18	637.782
#393	HESX1	6	15	21	955.851
#394	HES1	6	9	15	429.402
#395	NEUROG1	6	13	19	1316.822
#396	CREBZF	6	15	21	865.476
#397	SP1	6	20	26	528.693
#398	ZNF157	6	12	18	1205.525
#399	FOXK2	6	14	20	739.982
#400	ZNF446	6	9	15	1012.575
#401	NFX1	6	16	22	858.345
#402	ZIC1	6	17	23	749.073
#403	MEOX2	6	19	25	756.212
#404	MYF5	6	13	19	882.326
#405	ETV2	6	11	17	674.634
#406	FOXE1	6	16	22	1169.424
#407	IKZF3	6	11	17	1257.081
#408	NEUROD1	6	14	20	1041.118
#409	ZNF140	6	12	18	717.089
#410	NKX2-5	6	13	19	498.607
#411	TAF1B	6	5	11	381.194
#412	FOSL1	6	12	18	723.706
#413	SOX15	6	15	21	1404.189
#414	TAF13	6	13	19	653.681
#415	IRF4	6	12	18	1191.627
#416	IRF5	6	12	18	718.802
#417	FOXN2	6	7	13	451.176
#418	POU3F1	5	10	15	809.981
#419	NR6A1	5	10	15	653.381
#420	DLX6	5	9	14	471.512
#421	CBFA2T2	5	15	20	697.38
#422	TEF	5	12	17	828.194
#423	TBX5	5	11	16	447.734
#424	C11orf9	5	9	14	546.284
#425	ZNF643	5	10	15	638.694
#426	SOX30	5	11	16	879.659
#427	ATF5	5	12	17	569.476
#428	NR1I2	5	8	13	581.989
#429	IRF6	5	8	13	218.361
#430	PRRX2	5	13	18	767.586
#431	TSC22D2	5	13	18	880.897
#432	RFXAP	5	15	20	1111.053
#433	FOXH1	5	12	17	685.855
#434	HOXA1	5	11	16	663.601
#435	TCF21	5	13	18	463.069
#436	FOXL2	5	11	16	733.717
#437	KDM5B	5	10	15	600.125
#438	MZF1	5	17	22	1519.763
#439	IRX4	5	11	16	685.405
#440	FOXG1	5	13	18	887.707
#441	ZNF83	5	11	16	697.096
#442	BLZF1	5	12	17	558.543
#443	POU3F3	5	9	14	751.047
#444	NFIC	5	9	14	492.952
#445	PGR	5	11	16	739.586
#446	HMX1	5	10	15	601.696
#447	NKX2-8	5	13	18	924.32
#448	MYCN	5	15	20	803.508
#449	FOSB	5	10	15	823.619
#450	HOXA3	5	11	16	973.859
#451	PPARD	5	15	20	1323.491
#452	NFATC4	5	14	19	840.477
#453	ZFP37	5	13	18	828.116
#454	SOX11	5	13	18	536.388
#455	POU6F2	5	15	20	1347.18
#456	VDR	5	9	14	576.198
#457	ZGPAT	5	14	19	998.638
#458	CREB5	5	10	15	515.987
#459	FOSL2	5	12	17	337.628
#460	PAX8	4	12	16	546.117
#461	PPBPL2	4	9	13	253.615
#462	ZFHX3	4	12	16	320.359
#463	SALL1	4	14	18	617.901
#464	ZNF175	4	11	15	557.797
#465	RUNX2	4	14	18	289.047
#466	HEY1	4	17	21	925.002
#467	ZNF154	4	13	17	661.023
#468	ZHX3	4	13	17	564.324
#469	ZNF287	4	15	19	832.611
#470	ZBTB48	4	16	20	930.961
#471	CSRNP3	4	13	17	529.165
#472	RXRA	4	11	15	350.635
#473	ALX3	4	10	14	438.694
#474	GSC2	4	9	13	259.154
#475	TP63	4	11	15	443.096
#476	SCAND2	4	14	18	783.66
#477	WT1	4	11	15	558.371
#478	PRDM2	4	14	18	589.487
#479	MBD1	4	13	17	330.198
#480	MLXIPL	4	14	18	645.376
#481	GABPB1	4	18	22	736.683
#482	PAX7	3	9	12	214.094
#483	ZNF3	3	10	13	396.157
#484	HOXD1	3	12	15	588.206
#485	HNF1B	3	11	14	266.353
#486	ZSCAN12	3	10	13	782.434
#487	GCM1	3	15	18	811.974
#488	REL	3	10	13	400.044
#489	TRIM29	3	12	15	348.252
#490	TRIM25	3	9	12	352.994
#491	EMX1	3	10	13	360.162
#492	ZNF41	3	10	13	503.396
#493	POU3F2	3	10	13	369.656
#494	ASCL1	2	16	18	373.085
#495	ETV4	2	13	15	167.688
#496	STRN3	2	11	13	214.94
#497	ALX4	2	18	20	411.153
#498	ELK1	2	15	17	331.991
#499	WNT5A	2	15	17	387.686
#500	SNAPC5	1	15	16	193.171