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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MAF	58	1	59	32.103
#2	ZFPM2	43	5	48	1079.624
#3	HLF	43	3	46	230.233
#4	GATA6	40	8	48	8476.782
#5	FOXL2	38	7	45	2045.6
#6	FOXO1	37	3	40	122.312
#7	ELF3	36	10	46	803.039
#8	NR3C2	33	6	39	1374.376
#9	MEIS1	33	7	40	5168.456
#10	FOXN3	31	7	38	962.754
#11	MEF2C	31	3	34	374.943
#12	TCF21	31	6	37	412.539
#13	NR2F6	31	7	38	624.784
#14	KLF2	31	6	37	431.235
#15	SCAND1	29	10	39	9770.555
#16	TCF4	29	6	35	1288.907
#17	ZEB2	29	5	34	1483.974
#18	AFF1	28	8	36	1716.201
#19	HMGA1	28	9	37	358.595
#20	CBFB	28	6	34	1232.987
#21	SMAD4	27	11	38	2062.271
#22	GAS7	27	3	30	201.644
#23	MEIS2	26	15	41	4031.077
#24	ENO1	26	5	31	447.501
#25	NFATC4	26	8	34	2462.926
#26	MLL	25	10	35	597.095
#27	NFE2L2	25	6	31	1038.811
#28	HDAC2	25	9	34	3695.743
#29	ARNT	24	10	34	427.51
#30	ZNF281	24	14	38	6735.891
#31	ZNF135	24	10	34	2143.757
#32	ZNF217	23	10	33	855.721
#33	GLI2	23	10	33	1423.58
#34	PBX3	23	9	32	320.186
#35	TCEAL1	23	9	32	400.809
#36	NR2F1	23	11	34	3752.571
#37	CITED2	23	11	34	1797.391
#38	STRN3	22	8	30	5603.378
#39	RBPJ	22	6	28	1902.56
#40	SNAI2	22	10	32	3072.792
#41	TCF7L1	22	11	33	2913.429
#42	KLF5	22	9	31	788.789
#43	NFAT5	21	5	26	458.524
#44	HCLS1	21	13	34	1905.984
#45	ZFP36L2	21	6	27	1856.275
#46	RXRA	21	9	30	987.902
#47	TEAD4	21	5	26	677.884
#48	SOX17	21	7	28	596.293
#49	EGR1	21	6	27	979.384
#50	FOS	21	4	25	326.467
#51	KLF11	20	8	28	562.598
#52	ESRRA	20	11	31	629.54
#53	THRA	20	9	29	220.78
#54	TP53	20	11	31	12244.644
#55	TFDP2	20	11	31	7227.71
#56	RFXANK	20	9	29	530.958
#57	IRF7	20	11	31	913.56
#58	TAF7	20	11	31	626.606
#59	TGIF2	20	10	30	1073.614
#60	PTTG1	20	9	29	1605.54
#61	RUNX1T1	19	12	31	2984.402
#62	HNRNPAB	19	7	26	316.959
#63	TWIST1	19	14	33	7301.655
#64	VAX2	19	7	26	738.83
#65	SALL1	19	10	29	1287.066
#66	PURA	19	13	32	636.466
#67	IRF6	19	4	23	143.56
#68	BACH2	19	8	27	616.102
#69	ZFP36L1	19	9	28	474.954
#70	STAT6	18	9	27	1569.473
#71	NR4A2	18	7	25	659.706
#72	FOXO3	18	14	32	2997.501
#73	AHR	18	13	31	2925.699
#74	WT1	18	10	28	5222.462
#75	PHF1	18	9	27	1002.581
#76	HSF2	18	9	27	806.881
#77	YBX1	18	11	29	334.733
#78	ZNF45	18	10	28	2372.04
#79	YY1	18	3	21	2211.31
#80	NR2C1	17	9	26	1462.815
#81	NFE2L1	17	11	28	423.873
#82	TFAM	17	8	25	1447.349
#83	HOXB7	17	11	28	1629.487
#84	FUBP1	17	5	22	1263.03
#85	NR1H4	17	6	23	77.416
#86	CREB1	17	11	28	2405.544
#87	BHLHE40	17	8	25	547.382
#88	LEF1	17	12	29	1311.835
#89	NR3C1	17	16	33	3476.065
#90	ETV5	17	14	31	1713.508
#91	ZNF238	16	6	22	1305.686
#92	ATF2	16	6	22	572.556
#93	KLF4	16	6	22	615.855
#94	SPDEF	16	12	28	1618.447
#95	ZNF117	16	8	24	4195.786
#96	KLF9	16	15	31	3382.809
#97	CEBPA	16	12	28	1034.256
#98	PPARG	16	12	28	985.064
#99	FOSB	15	4	19	1188.216
#100	MLXIPL	15	17	32	3649.816
#101	HMGB1	15	12	27	3905.275
#102	TFCP2	15	11	26	1386.531
#103	FOXF2	15	9	24	2623.834
#104	JUND	15	11	26	1177.107
#105	CEBPD	15	6	21	1972.443
#106	NR5A2	15	13	28	2976.71
#107	RELB	15	11	26	984.645
#108	HOXB2	15	13	28	572.331
#109	SIM2	14	10	24	2480.873
#110	MITF	14	11	25	3707.465
#111	HIF1A	14	10	24	1019.519
#112	NFATC3	14	12	26	1935.287
#113	ZNF148	14	6	20	1981.095
#114	GATA4	14	9	23	597.11
#115	SOX11	14	6	20	1329.755
#116	RERE	14	7	21	762.489
#117	ZNF277	14	7	21	2657.773
#118	NFYA	14	9	23	2069.965
#119	TCF12	14	10	24	965.554
#120	CDKN2A	14	8	22	822.68
#121	ZNF274	14	10	24	3768.025
#122	SCML2	14	8	22	416.599
#123	JUNB	14	2	16	136.303
#124	POU4F1	14	8	22	1038.068
#125	BATF	14	5	19	521.378
#126	CTBP1	14	9	23	1318.153
#127	RORC	14	8	22	616.156
#128	HOXD1	14	15	29	2430.879
#129	SCML1	14	9	23	1107.728
#130	HEY1	14	7	21	983.694
#131	TFAP2C	14	12	26	901.896
#132	PAX8	13	7	20	923.946
#133	ZNF219	13	13	26	3541.392
#134	SIX2	13	7	20	1538.603
#135	TGIF1	13	6	19	1621.07
#136	NFIB	13	9	22	1172.426
#137	E2F1	13	11	24	407.746
#138	MYBL2	13	14	27	1623.244
#139	PITX2	13	12	25	4587.743
#140	STAT5B	13	7	20	256.66
#141	ZNF91	13	12	25	1589.88
#142	CREBL2	13	13	26	878.514
#143	POU2F3	13	8	21	419.403
#144	HIF3A	13	13	26	3461.639
#145	IKZF1	13	5	18	1408.315
#146	ZNF287	13	18	31	1959.259
#147	ELF4	13	9	22	1118.576
#148	CREBZF	13	11	24	2614.735
#149	GATA2	13	9	22	1561.397
#150	SOX10	12	14	26	2725.173
#151	NKX2-5	12	7	19	1004.23
#152	AEBP1	12	19	31	1088.108
#153	RCAN1	12	9	21	1414.955
#154	ZNF189	12	12	24	407.216
#155	NR4A1	12	9	21	275.67
#156	HOXB1	12	13	25	4326.689
#157	ATF1	12	11	23	859.483
#158	GTF2H3	12	11	23	1090.675
#159	RB1	12	9	21	3276.953
#160	ZBTB48	12	6	18	1085.792
#161	HOXA11	12	8	20	4798.668
#162	LMO4	12	6	18	1969.581
#163	SMAD5	12	7	19	4179.598
#164	BACH1	12	9	21	904.694
#165	SOX9	12	11	23	1766.122
#166	ESRRG	12	9	21	1932.378
#167	MEOX2	12	15	27	1382.96
#168	ATF6	12	12	24	902.877
#169	CEBPB	12	9	21	454.15
#170	ZNF232	12	12	24	977.105
#171	MLLT10	12	13	25	1061.795
#172	MTA1	12	8	20	1556.808
#173	ESR1	12	12	24	1766.317
#174	NFIL3	12	5	17	212.043
#175	EHF	12	12	24	548.055
#176	HMGA2	12	13	25	1211.229
#177	AATF	12	8	20	2540.075
#178	EGR3	11	9	20	224.739
#179	ZNF24	11	5	16	228.9
#180	PLAGL2	11	12	23	1212.388
#181	PHTF1	11	11	22	1090.923
#182	RUNX3	11	12	23	2369.238
#183	TFDP3	11	6	17	628.532
#184	ARNTL2	11	15	26	2744.075
#185	KLF10	11	4	15	329.943
#186	HR	11	7	18	4057.414
#187	NR2E1	11	8	19	1676.413
#188	UBN1	11	7	18	2135.517
#189	HOXA5	11	7	18	965.139
#190	TRIM28	11	13	24	1312.106
#191	TEF	11	10	21	757.621
#192	PAX7	11	9	20	781.565
#193	EPAS1	11	12	23	957.818
#194	TRPS1	11	11	22	1350.556
#195	TSC22D1	11	11	22	754.964
#196	PROX1	11	9	20	792.93
#197	TEAD1	11	13	24	960.615
#198	POU3F4	10	10	20	1855.976
#199	PLSCR1	10	12	22	2033.287
#200	ARID4A	10	9	19	258.414
#201	MYC	10	14	24	1423.751
#202	PAX6	10	12	22	1216.938
#203	PPARA	10	8	18	616.39
#204	MYOG	10	7	17	1248.354
#205	KDM5A	10	6	16	946.357
#206	HSF4	10	10	20	2105.737
#207	MYCN	10	16	26	3325.999
#208	NR1H3	10	13	23	2508.983
#209	NR2E3	10	14	24	3646.741
#210	ETV6	10	9	19	607.859
#211	HDAC1	10	8	18	3451.033
#212	CSDA	10	7	17	746.656
#213	SLC2A4RG	10	12	22	2114.901
#214	HOXA10	10	10	20	1726.842
#215	HSF1	10	15	25	1006.787
#216	ATF3	10	9	19	840.953
#217	CNOT7	10	9	19	723.124
#218	C11orf9	10	9	19	549.731
#219	SOX4	10	17	27	1871.239
#220	GTF2H4	10	10	20	1890.398
#221	DMRT1	10	16	26	2879.752
#222	STAT5A	10	8	18	1038.905
#223	TRIM29	10	16	26	784.994
#224	HOXC4	10	14	24	1938.123
#225	HOXC13	10	12	22	1839.636
#226	HOXC11	10	9	19	1344.905
#227	SATB1	9	7	16	539.101
#228	HOXB5	9	8	17	316.154
#229	ZNF134	9	8	17	1317.969
#230	KLF7	9	9	18	173.7
#231	MAFF	9	10	19	588.33
#232	KLF6	9	13	22	1133.488
#233	REL	9	14	23	1448.706
#234	NPAT	9	12	21	1887.622
#235	BTG2	9	6	15	136.061
#236	ZFP37	9	12	21	370.017
#237	SREBF1	9	9	18	1401.371
#238	ISL1	9	15	24	1512.824
#239	FOXO4	9	13	22	586.239
#240	POU6F1	9	16	25	1329.395
#241	HOXB6	9	8	17	764.534
#242	HOXD10	9	9	18	1361.57
#243	CEBPE	9	5	14	556.117
#244	MEF2A	9	14	23	1758.802
#245	ATF5	9	17	26	495.798
#246	MEF2D	9	8	17	1334.641
#247	MSC	9	11	20	2381.558
#248	HEY2	9	10	19	1576.211
#249	HNF1B	9	11	20	1252.926
#250	HOXD4	9	11	20	4623.701
#251	CDX2	9	8	17	1628.186
#252	FOXH1	9	14	23	2233.102
#253	NFIC	8	15	23	828.822
#254	RARG	8	14	22	3501.074
#255	NFATC1	8	12	20	975.159
#256	TBX1	8	12	20	4315.904
#257	BCL3	8	15	23	1077.184
#258	AFF4	8	12	20	1452.534
#259	ZNF140	8	13	21	565.383
#260	ZNF83	8	14	22	1060.038
#261	SRF	8	13	21	1092.405
#262	REXO4	8	8	16	814.379
#263	ELK4	8	9	17	1270.645
#264	ATOH1	8	10	18	908.628
#265	NEUROG1	8	10	18	2360.437
#266	AR	8	16	24	547.825
#267	PBX2	8	12	20	1258.023
#268	FOXN2	8	9	17	661.18
#269	PITX3	8	8	16	674.246
#270	PFDN1	8	7	15	914.799
#271	ARNTL	8	14	22	588.52
#272	EGR2	8	6	14	491.953
#273	HOXA9	8	8	16	1107.782
#274	ETS1	8	7	15	693.285
#275	FOXJ1	8	15	23	359.415
#276	HOXD9	8	14	22	628.187
#277	RORB	8	9	17	1087.897
#278	TCF7	7	9	16	703.356
#279	ZNF165	7	18	25	481.676
#280	HIC1	7	14	21	1600.821
#281	SIX1	7	10	17	801.855
#282	VDR	7	15	22	408.763
#283	MYF5	7	9	16	1446.524
#284	HOXA1	7	14	21	2191.548
#285	STAT1	7	16	23	884.382
#286	PKNOX1	7	11	18	2018.165
#287	SMAD6	7	17	24	1285.181
#288	TAF12	7	13	20	1873.917
#289	WNT5A	7	13	20	852.065
#290	HOXA4	7	10	17	1190.684
#291	VTN	7	10	17	2951.739
#292	ALX4	7	11	18	1895.126
#293	ZNF167	7	11	18	1782.892
#294	HOXD12	7	9	16	1714.397
#295	FOXC1	7	9	16	1851.312
#296	NKX2-1	7	7	14	317.646
#297	RFX1	7	10	17	1180.136
#298	FOXD1	7	6	13	754.464
#299	GATA3	7	8	15	910.456
#300	JUN	7	11	18	1360.363
#301	SCRT1	7	7	14	1462.556
#302	KLF12	7	12	19	1595.974
#303	SP140	7	9	16	419.603
#304	TADA3	7	12	19	1828.56
#305	GLI3	7	12	19	568.08
#306	XBP1	7	11	18	2032.678
#307	HAND1	7	11	18	1287.231
#308	MMP14	7	9	16	506.079
#309	ZNF175	7	9	16	316.436
#310	SOX13	7	12	19	554.07
#311	IRF9	7	9	16	381.541
#312	POU6F2	7	10	17	994.675
#313	RARA	7	12	19	652.252
#314	GTF2IRD1	7	10	17	541.245
#315	RFX5	7	11	18	344.141
#316	ZBTB25	7	8	15	681.347
#317	VENTX	7	6	13	1353.693
#318	SOX12	7	12	19	1150.622
#319	SHOX	7	11	18	1430.58
#320	SRY	6	9	15	888.6
#321	CBL	6	7	13	1391.989
#322	FOXD3	6	9	15	1093.08
#323	TLX3	6	12	18	3223.273
#324	DLX4	6	9	15	834.817
#325	KLF3	6	9	15	553.466
#326	POU3F1	6	9	15	1494.013
#327	FOXE1	6	14	20	7337.949
#328	EN2	6	8	14	1044.516
#329	LHX2	6	16	22	3231.116
#330	ETS2	6	9	15	1460.379
#331	STAT3	6	9	15	617.417
#332	SMAD1	6	10	16	802.767
#333	PHOX2B	6	9	15	1567.388
#334	TBX5	6	11	17	1767.765
#335	HIRA	6	8	14	703.952
#336	GABPB1	6	13	19	1192.797
#337	IRX4	6	10	16	2085.305
#338	NR2C2	6	10	16	2303.521
#339	IRF8	6	13	19	625.4
#340	TBX10	6	12	18	1937.065
#341	BARX1	6	14	20	2176.694
#342	OVOL1	6	13	19	992.942
#343	ATF6B	6	11	17	1429.476
#344	FOSL2	6	14	20	814.351
#345	MEOX1	6	16	22	570.016
#346	ASCL1	6	10	16	1117.473
#347	SOX5	6	14	20	1001.817
#348	NPAS2	6	10	16	1127.078
#349	ZNF174	6	11	17	1307.067
#350	T	6	12	18	974.135
#351	GABPA	6	14	20	543.602
#352	USF2	6	7	13	448.011
#353	PRDM2	6	12	18	547.626
#354	MSX1	5	17	22	1842.565
#355	TBR1	5	6	11	411.397
#356	TSC22D4	5	15	20	1185.8
#357	PBX1	5	11	16	704.979
#358	TBX2	5	16	21	1607.289
#359	GCM1	5	10	15	1722.229
#360	SOX15	5	11	16	381.753
#361	IRX5	5	11	16	733.097
#362	PHOX2A	5	15	20	4062.846
#363	NFE2L3	5	14	19	223.194
#364	HOXD11	5	9	14	688.874
#365	TBX19	5	13	18	542.522
#366	TFAP4	5	13	18	771.15
#367	BNC1	5	12	17	1086.051
#368	TFEC	5	10	15	1749.611
#369	NKX6-1	5	6	11	1013.594
#370	DLX2	5	9	14	1321.128
#371	NR4A3	5	13	18	941.95
#372	E2F3	5	11	16	207.69
#373	LZTS1	5	11	16	643.437
#374	NKX3-2	5	10	15	942.262
#375	TFAP2A	5	13	18	1108.14
#376	TP73	5	10	15	1631.111
#377	SOX30	5	8	13	562.021
#378	VSX1	5	13	18	775.124
#379	HOXD13	5	10	15	608.443
#380	DBP	5	8	13	236.205
#381	POU1F1	5	13	18	937.759
#382	LHX6	5	8	13	929.767
#383	EGR4	5	8	13	678.718
#384	CREM	5	8	13	753.454
#385	HOXD3	5	13	18	2223.335
#386	RAX	5	11	16	990.538
#387	BCL6	5	12	17	1741.618
#388	RARB	5	12	17	823.045
#389	CTNNB1	5	7	12	182.179
#390	RBPJL	5	10	15	599.957
#391	TCF15	4	11	15	504.343
#392	ESR2	4	15	19	1310.098
#393	PDX1	4	11	15	919.315
#394	RORA	4	8	12	266.122
#395	HOXC8	4	7	11	697.763
#396	FOXI1	4	13	17	870.149
#397	PLAG1	4	16	20	2480.145
#398	NR0B1	4	11	15	646.518
#399	PGR	4	13	17	788.69
#400	SMAD9	4	13	17	496.485
#401	NEUROD1	4	10	14	350.457
#402	ERF	4	15	19	840.748
#403	BATF3	4	9	13	459.883
#404	CREB5	4	11	15	352.688
#405	MAFB	4	13	17	872.226
#406	HOXC5	4	11	15	962.863
#407	BCL11B	4	11	15	368.818
#408	FOXA2	4	12	16	217.516
#409	EN1	4	13	17	2472.631
#410	FOXC2	4	11	15	1135.186
#411	CBFA2T3	4	9	13	752.42
#412	ZFHX3	4	17	21	617.491
#413	SLC26A3	4	7	11	1639.697
#414	HOXA2	4	9	13	806.502
#415	HOXC10	4	10	14	607.847
#416	ZNF639	4	10	14	1025.196
#417	LHX1	4	11	15	398.3
#418	RUNX1	4	12	16	1444.782
#419	TFAP2B	4	16	20	1581.711
#420	ZNF157	4	12	16	911.529
#421	GSC2	4	17	21	1759.761
#422	MYF6	4	10	14	496.149
#423	FOXD2	4	11	15	1357.741
#424	HNF4A	4	9	13	1239.937
#425	TFDP1	4	16	20	838.941
#426	YEATS4	4	13	17	841.304
#427	NR5A1	4	12	16	118.274
#428	FOXB1	4	8	12	292.853
#429	SOX18	4	15	19	736.152
#430	PAX4	4	4	8	340.447
#431	ESRRB	4	11	15	898.927
#432	NR1I2	3	14	17	533.665
#433	KLF1	3	9	12	622.686
#434	PRRX2	3	11	14	1159.436
#435	ELK3	3	9	12	238.828
#436	CITED1	3	8	11	237.25
#437	ELF5	3	13	16	2256.186
#438	HOXA6	3	16	19	3666.635
#439	MSX2	3	15	18	774.902
#440	ZNF215	3	11	14	1313.02
#441	RUNX2	3	13	16	1066.335
#442	NPAS1	3	10	13	1631.379
#443	MNX1	3	13	16	764.644
#444	FOXG1	3	14	17	987.158
#445	E2F2	3	11	14	1030.576
#446	HNF4G	3	11	14	4029.624
#447	PRRX1	3	14	17	134.614
#448	ALX1	3	8	11	509.846
#449	PPBPL2	3	12	15	1785.584
#450	RFX3	3	13	16	906.565
#451	POU4F3	3	12	15	795.786
#452	BLZF1	3	14	17	373.9
#453	HESX1	3	10	13	366.92
#454	ELK1	3	12	15	1208.699
#455	SIM1	3	14	17	502.665
#456	NKX3-1	3	8	11	242.678
#457	LHX5	3	13	16	920.615
#458	NKX2-8	3	16	19	868.967
#459	SCAND2	3	11	14	197.564
#460	ZNF80	3	19	22	484.632
#461	PTH	3	12	15	548.445
#462	FOXA1	3	10	13	730.301
#463	HNF1A	3	9	12	858.135
#464	POU3F3	3	13	16	1179.251
#465	FOXE3	3	11	14	892.182
#466	SPI1	3	11	14	236.907
#467	EVX1	3	14	17	604.207
#468	GBX2	3	15	18	475.041
#469	FEV	3	8	11	842.57
#470	DLX6	3	11	14	231.886
#471	HAND2	3	9	12	61.444
#472	POU3F2	2	12	14	356.276
#473	NR6A1	2	9	11	100.652
#474	ZIC1	2	19	21	333.728
#475	HMX1	2	15	17	705.379
#476	ARID3A	2	8	10	652.376
#477	HOXA3	2	16	18	1203.399
#478	SOX21	2	14	16	548.019
#479	MXD1	2	11	13	640.989
#480	NFIX	2	9	11	268.157
#481	SIX3	2	10	12	481.072
#482	PAX3	2	11	13	209.805
#483	ASCL2	2	15	17	1171.914
#484	TAF13	2	19	21	810.163
#485	ZNF155	2	8	10	225.543
#486	ALX3	2	15	17	897.774
#487	TRIM25	2	15	17	415.258
#488	PRDM1	2	11	13	352.099
#489	FOSL1	2	15	17	329.427
#490	ZIC3	2	11	13	1595.845
#491	HOXB8	1	11	12	106.084
#492	PITX1	1	13	14	244.271
#493	HES1	1	9	10	43.952
#494	NFE2	1	13	14	118.609
#495	HOXB3	1	15	16	95.48
#496	IKZF3	1	8	9	197.148
#497	ZNF85	1	15	16	46.737
#498	ONECUT2	1	14	15	794.684
#499	RFXAP	1	10	11	593.792
#500	MAFK	1	13	14	207.375