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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NOLC1	42	3	45	748.727
#2	BRD8	39	8	47	8364.307
#3	VSX1	38	4	42	775.535
#4	NEUROD2	37	2	39	55.552
#5	CNBP	36	5	41	1779.238
#6	FLI1	33	2	35	81.197
#7	HHEX	33	5	38	3194.667
#8	NR2F6	33	6	39	1353.245
#9	DMTF1	31	10	41	2211.978
#10	SCMH1	31	7	38	26694.08
#11	RNF4	30	8	38	1821.856
#12	RERE	30	6	36	4004.731
#13	YY1	29	3	32	1426.937
#14	NFIB	29	11	40	10146.301
#15	BLZF1	29	7	36	19195.994
#16	ZRANB2	28	5	33	220.096
#17	C11orf9	28	5	33	597.005
#18	VDR	28	4	32	83.128
#19	LHX9	27	3	30	336.305
#20	ZNF83	27	3	30	252.277
#21	ZBTB25	27	3	30	5607.159
#22	ZFP36L1	27	8	35	3936.135
#23	E2F4	26	1	27	14.322
#24	FOXJ3	26	5	31	726.954
#25	ZHX2	25	6	31	5519.587
#26	NFAT5	25	9	34	938.942
#27	NFIC	25	7	32	3293.042
#28	ALX3	25	7	32	616.677
#29	STAT5B	24	11	35	2448.397
#30	HOXA6	24	5	29	1096.732
#31	ETV7	23	5	28	2794.338
#32	MEIS2	22	11	33	3825.592
#33	NFATC3	22	3	25	1957.384
#34	ATF2	22	11	33	1987.53
#35	AFF4	22	6	28	411.531
#36	ADNP	22	6	28	1232.065
#37	LHX3	22	6	28	513.792
#38	MBD1	22	9	31	2088.616
#39	FOXN4	21	5	26	1503.131
#40	FUBP1	21	11	32	1842.757
#41	CEBPB	21	8	29	1841.861
#42	PBX1	21	8	29	1396.282
#43	MAX	21	10	31	1143.391
#44	GATA4	21	8	29	10799.396
#45	AFF1	20	8	28	631.92
#46	TCF7L2	20	11	31	1077.832
#47	CREB1	20	10	30	2659.406
#48	CREB3L2	20	9	29	8163.28
#49	ASCL1	20	3	23	552.538
#50	EN2	20	8	28	990.22
#51	HNRNPAB	20	9	29	22005.852
#52	CREBZF	20	11	31	3082.871
#53	SOX5	19	9	28	977.918
#54	POU3F1	19	11	30	387.895
#55	TFEC	18	4	22	104.801
#56	ZNF85	18	10	28	741.519
#57	RELA	18	5	23	417.966
#58	HDAC1	18	5	23	612.544
#59	SNAPC5	18	10	28	3198.478
#60	MEF2A	18	8	26	2073.104
#61	ZKSCAN3	18	5	23	304.473
#62	EDF1	18	9	27	402.292
#63	BTAF1	18	7	25	2044.211
#64	ZNF496	18	6	24	8418.025
#65	TAF7	18	5	23	342.058
#66	IRF8	18	8	26	880.85
#67	ZNF154	18	8	26	361.843
#68	ZHX1	17	10	27	677.003
#69	BCL3	17	9	26	4715.756
#70	MEIS3P1	17	6	23	2344.715
#71	HSF1	17	10	27	2412.309
#72	ELK3	17	12	29	4061.529
#73	ZFP36L2	17	7	24	711.856
#74	RCOR1	17	15	32	16963.69
#75	JUNB	17	2	19	277.401
#76	ZNF169	17	11	28	9397.647
#77	EPAS1	17	7	24	1677.218
#78	PPARD	17	8	25	1003.615
#79	EBF1	17	5	22	370.025
#80	TRIM25	17	7	24	592.681
#81	GATA3	17	2	19	75.494
#82	TARDBP	17	7	24	2040.398
#83	TBX4	17	5	22	638.18
#84	MEF2D	16	11	27	1671.875
#85	PHF1	16	5	21	905.376
#86	SP3	16	12	28	1097.034
#87	FOXC2	16	8	24	266.192
#88	NR2F2	16	12	28	1310.733
#89	C12orf28	16	8	24	1156.07
#90	ZNF628	16	9	25	5520.009
#91	KLF12	16	5	21	6605.852
#92	NFIL3	16	12	28	2781.37
#93	BCL6	15	14	29	3561.111
#94	TEAD3	15	10	25	2438.736
#95	TFE3	15	11	26	2364.443
#96	ZSCAN16	15	11	26	2333.251
#97	SPIB	15	7	22	1405.704
#98	SPI1	15	6	21	312.133
#99	TRIM22	15	12	27	3793.631
#100	CSRNP1	15	2	17	183.16
#101	ZNF3	15	8	23	210.906
#102	PRDM2	15	11	26	7799.474
#103	SOX13	14	9	23	195.364
#104	HMG20B	14	6	20	1697.329
#105	BTG2	14	9	23	2507.032
#106	NPAT	14	9	23	7159.752
#107	ZNF91	14	8	22	1154.32
#108	ESRRA	14	4	18	129.575
#109	GLIS2	14	7	21	499.807
#110	TP73	14	9	23	278.116
#111	CSDA	14	9	23	2178.379
#112	VENTX	14	5	19	356.503
#113	PRRX1	14	5	19	300.241
#114	NR2F1	14	7	21	6427.036
#115	HDAC2	14	10	24	11108.121
#116	POU2F1	14	10	24	1210.626
#117	MEF2C	14	6	20	382.11
#118	KLF3	14	11	25	480.616
#119	NFIA	13	15	28	6668.868
#120	BHLHE40	13	8	21	2070.932
#121	CTBP1	13	9	22	3538.808
#122	NCOR1	13	12	25	1959.792
#123	ELF2	13	11	24	1742.7
#124	TCF3	13	13	26	1785.603
#125	HOPX	13	10	23	835.909
#126	PBX2	13	7	20	2136.967
#127	MAFG	13	11	24	784.586
#128	TCF20	13	8	21	39254.828
#129	GAS7	13	11	24	10679.042
#130	LASS5	13	11	24	1706.516
#131	TFCP2	13	7	20	401.482
#132	ZNF238	13	12	25	1033.57
#133	E2F7	13	7	20	147.513
#134	THRA	13	6	19	22723.982
#135	SUPT6H	13	5	18	1133.986
#136	PDX1	13	6	19	521.944
#137	SCAND1	13	9	22	475.978
#138	HMGB1	12	10	22	1284.89
#139	C5orf41	12	10	22	9624.111
#140	ELF1	12	3	15	4750.665
#141	IRF6	12	13	25	2484.746
#142	NR1I2	12	8	20	243.743
#143	FOSL2	12	13	25	5406.289
#144	HES6	12	9	21	17246.109
#145	NR2C2	12	7	19	336.788
#146	LMX1A	12	8	20	230.578
#147	HOXD10	12	11	23	6389.658
#148	TCF21	12	6	18	364.475
#149	GTF2H3	12	5	17	1898.894
#150	SOX6	12	10	22	941.122
#151	GABPB1	12	8	20	113.907
#152	MAFF	12	12	24	16446.847
#153	CNOT7	12	6	18	2431.208
#154	STAT3	12	10	22	1541.849
#155	SCML1	12	11	23	823.946
#156	MLL	12	12	24	700.214
#157	HOXC8	12	10	22	1978.506
#158	MYT1	12	8	20	247.434
#159	CUX1	12	10	22	906.695
#160	RBPJ	11	9	20	296.975
#161	POU6F1	11	9	20	7128.427
#162	TGIF2LY	11	6	17	455.948
#163	PPARA	11	10	21	2006.995
#164	RB1	11	5	16	237.91
#165	MSL3	11	11	22	1192.633
#166	MLX	11	6	17	315.902
#167	RUNX2	11	8	19	351.743
#168	GATAD1	11	9	20	3082.177
#169	RBCK1	11	10	21	1037.189
#170	HESX1	11	8	19	661.348
#171	FOXN3	11	9	20	3057.192
#172	TGIF1	11	13	24	30836.208
#173	IRF2	11	8	19	335.568
#174	HOXB13	11	6	17	716.177
#175	PBX3	11	9	20	736.422
#176	TP63	11	8	19	1213.557
#177	GLIS3	11	11	22	498.417
#178	ZFHX3	11	8	19	460.092
#179	DMRT1	11	6	17	506.522
#180	LCOR	11	18	29	2929.421
#181	KLF5	11	12	23	639.365
#182	RUNX1	11	8	19	671.566
#183	CREB3L4	11	10	21	2586.411
#184	SOX11	10	8	18	937.929
#185	ZNF131	10	11	21	511.813
#186	YEATS4	10	11	21	406.393
#187	KLF10	10	10	20	1362.442
#188	HIF1A	10	12	22	696.327
#189	SOX30	10	4	14	473.139
#190	NKX3-1	10	7	17	3903.691
#191	SOX4	10	11	21	1942.352
#192	PHTF1	10	11	21	1625.626
#193	MSRB2	10	13	23	1862.293
#194	ZNF438	10	3	13	81.947
#195	BACH1	10	12	22	2863.196
#196	FOXN2	10	14	24	1413.031
#197	LHX2	10	9	19	543.026
#198	HOXD4	10	5	15	386.194
#199	TBX10	10	10	20	2701.787
#200	DLX2	10	10	20	2599.377
#201	TAF10	10	4	14	998.651
#202	HMGA1	10	9	19	1427.774
#203	PAX7	9	7	16	569.034
#204	HES1	9	14	23	2680.235
#205	RCAN1	9	11	20	7125.201
#206	FOXP1	9	11	20	9529.281
#207	UBN1	9	11	20	422.078
#208	FOXE1	9	8	17	1353.142
#209	ELK4	9	9	18	1281.401
#210	BATF3	9	12	21	2417.659
#211	PURB	9	15	24	666.717
#212	MITF	9	14	23	6954.982
#213	TFAP2B	9	11	20	2160.064
#214	PURA	9	10	19	1409.029
#215	EGR2	9	7	16	3077.535
#216	TCF4	9	11	20	2750.925
#217	ETS1	9	6	15	2496.305
#218	TCF25	9	14	23	5031.67
#219	JUND	9	9	18	3041.227
#220	ZNF217	9	14	23	886.427
#221	STAT1	9	11	20	1886.61
#222	ESRRB	9	5	14	136.326
#223	RFX1	9	8	17	1405.373
#224	HOMEZ	9	5	14	5677.775
#225	KCNH8	8	7	15	2469.05
#226	ZNF75D	8	16	24	1073.556
#227	ZNF24	8	13	21	5305.809
#228	ZFHX2	8	9	17	3639.356
#229	ALS2CR8	8	4	12	113.453
#230	CDX2	8	10	18	1974.275
#231	HIC1	8	9	17	5987.309
#232	CCRN4L	8	11	19	1141.33
#233	GRHL2	8	7	15	988.81
#234	MAFK	8	9	17	11883.556
#235	CBFB	8	13	21	663.222
#236	SIX5	8	7	15	585.306
#237	MLLT10	8	4	12	202.699
#238	EGR1	8	7	15	572.202
#239	FOXI1	8	6	14	672.587
#240	POU1F1	8	8	16	723.24
#241	TCEAL1	8	9	17	2079.18
#242	ELF4	8	11	19	1479.111
#243	CSRNP3	8	10	18	2456.561
#244	NFE2L1	8	9	17	546.248
#245	PLSCR1	8	8	16	1062.93
#246	TFAP2A	8	10	18	1473.927
#247	ZNF434	7	8	15	719.794
#248	ARNT	7	13	20	1986.921
#249	CEBPD	7	11	18	4899.53
#250	SPDEF	7	10	17	3281.742
#251	SMAD2	7	13	20	326.388
#252	FOXD1	7	14	21	3065.021
#253	PHOX2A	7	10	17	374.075
#254	ZNF639	7	11	18	1033.566
#255	FOXH1	7	7	14	1376.466
#256	CRX	7	10	17	285.489
#257	HMGB2	7	14	21	4154.488
#258	HOXD13	7	9	16	366.595
#259	IRF1	7	11	18	680.485
#260	MTA1	7	8	15	837.158
#261	TBX20	7	6	13	88.481
#262	NR4A3	7	7	14	258.188
#263	HCLS1	7	10	17	2179.55
#264	TBX3	7	9	16	676.257
#265	ISL1	7	5	12	347.452
#266	SIM2	7	11	18	537.148
#267	ZNF281	7	9	16	1194.398
#268	TCF12	7	8	15	378.108
#269	SIN3A	7	11	18	2882.055
#270	ZNF449	7	5	12	1180.084
#271	MYT1L	7	1	8	570.339
#272	FOXK2	7	10	17	52235.999
#273	HNF4A	7	5	12	499.27
#274	HOXA7	7	16	23	1427.321
#275	E2F2	7	12	19	3878.549
#276	ZFPM1	7	4	11	76.058
#277	RXRA	7	10	17	583.635
#278	DLX4	7	8	15	4282.294
#279	PKNOX2	7	9	16	1255.609
#280	PPBPL2	7	7	14	3058.583
#281	CBFA2T2	6	12	18	611.063
#282	BNC1	6	6	12	115.123
#283	NR4A2	6	10	16	3553.158
#284	ZNF207	6	10	16	345.654
#285	HIF3A	6	7	13	602.19
#286	NFATC2	6	5	11	4674.515
#287	DLX3	6	8	14	180.418
#288	NFE2L2	6	13	19	1941.428
#289	FOXO3	6	15	21	2054.097
#290	ZNF483	6	6	12	105.604
#291	SPIC	6	6	12	5449.615
#292	STAT6	6	11	17	530.034
#293	LMO4	6	12	18	1682.209
#294	TSHZ3	6	7	13	663.453
#295	TFAP2C	6	10	16	422.118
#296	FEV	6	13	19	1611.256
#297	SNAPC4	6	11	17	2027.01
#298	RARA	6	5	11	176.258
#299	ZNF148	6	10	16	924.134
#300	TAF1B	6	5	11	238.455
#301	KLF6	6	11	17	591.373
#302	FBXW7	6	11	17	3625.923
#303	NFYC	6	4	10	928.13
#304	TEF	6	11	17	7656.722
#305	FOXA1	6	9	15	349.38
#306	IKZF1	6	12	18	354.543
#307	CREBBP	6	16	22	17606.161
#308	ZNF219	6	5	11	253.224
#309	ETS2	6	10	16	520.681
#310	HLF	6	14	20	1401.03
#311	YBX1	6	12	18	1678.085
#312	NFKB2	6	11	17	175.919
#313	SMAD1	6	12	18	9077.219
#314	ESR2	6	12	18	1282.652
#315	C1orf85	6	13	19	819.243
#316	C2orf3	5	9	14	268.907
#317	NFIX	5	11	16	7793.129
#318	HNRNPK	5	9	14	1100.468
#319	ZNF277	5	7	12	822.207
#320	FOXC1	5	16	21	619.986
#321	HOXA11	5	12	17	690.746
#322	DLX1	5	7	12	1759.311
#323	SPEN	5	9	14	599.545
#324	IRF5	5	7	12	5157.879
#325	ZNF268	5	13	18	864.47
#326	HOXA9	5	13	18	663.645
#327	MIXL1	5	6	11	222.038
#328	CBL	5	17	22	2006.799
#329	JUN	5	11	16	521.413
#330	FOXK1	5	13	18	686.636
#331	SOX7	5	12	17	4094.484
#332	ZFHX4	5	10	15	366.581
#333	NR4A1	5	14	19	4075.524
#334	TRERF1	5	13	18	7304.989
#335	MGA	5	13	18	1941.92
#336	CUX2	5	8	13	8722.135
#337	CDKN2A	5	6	11	485.556
#338	XBP1	5	14	19	7818.554
#339	ENO1	5	6	11	613.461
#340	ZNF37A	5	12	17	344.574
#341	HOXD1	5	11	16	1214.06
#342	ARID4A	5	9	14	1045.052
#343	EHF	5	13	18	6887.887
#344	ZNF71	5	7	12	65.21
#345	ETV5	5	11	16	2753.223
#346	RFX5	5	15	20	802.294
#347	IRX3	5	10	15	1233.752
#348	EGR3	4	11	15	2461.768
#349	NFXL1	4	14	18	2470.17
#350	FOSB	4	7	11	408.581
#351	SCAND2	4	6	10	90.198
#352	IRX2	4	9	13	270.847
#353	LASS6	4	10	14	83.219
#354	FOS	4	5	9	67.65
#355	MNX1	4	14	18	967.24
#356	AHR	4	16	20	1166.238
#357	ZFP42	4	8	12	2352.333
#358	TFAM	4	10	14	198.746
#359	TRPS1	4	9	13	703.025
#360	ESR1	4	17	21	4713.86
#361	ELF3	4	12	16	1734.864
#362	HOXA2	4	10	14	804.854
#363	SREBF1	4	12	16	747.613
#364	MECOM	4	14	18	1462.37
#365	TCF15	4	8	12	3563.921
#366	TFDP1	4	11	15	276.188
#367	KDM5B	4	9	13	930.205
#368	ZKSCAN1	4	11	15	1234.841
#369	ZNF135	4	11	15	1334.97
#370	ZNF33A	4	9	13	429.289
#371	PROX1	4	8	12	157.11
#372	KLF4	4	13	17	2496.284
#373	ETV3	4	7	11	116.509
#374	NPAS2	4	8	12	564.087
#375	STRN3	4	8	12	508.318
#376	PCGF2	4	14	18	2271.834
#377	FOXA2	4	9	13	224.612
#378	ARNTL2	4	7	11	340.97
#379	MEIS1	4	8	12	516.339
#380	E4F1	4	12	16	806.128
#381	TFCP2L1	4	9	13	845.859
#382	ARNTL	4	8	12	362.202
#383	SMAD6	4	8	12	567.693
#384	ZNF274	4	8	12	869.481
#385	PAX4	4	12	16	5425.897
#386	RARG	4	4	8	146.973
#387	HSF5	4	9	13	1084.728
#388	NFX1	4	11	15	857.053
#389	SMAD5	4	12	16	2101.767
#390	TSC22D3	4	10	14	3419.387
#391	GCFC1	3	14	17	1811.62
#392	AHCTF1	3	13	16	177.868
#393	AR	3	14	17	470.594
#394	PCGF6	3	8	11	26.54
#395	THRB	3	12	15	12087.768
#396	IRF7	3	9	12	794.238
#397	ZNF41	3	10	13	781.097
#398	FOXF1	3	16	19	588.087
#399	TBX6	3	6	9	104.786
#400	TFDP2	3	10	13	862.135
#401	BHLHE41	3	14	17	1833.303
#402	KDM5A	3	11	14	479.753
#403	SOX2	3	10	13	870.089
#404	NKX2-3	3	3	6	15.552
#405	ISL2	3	12	15	1247.085
#406	SP1	3	12	15	362.998
#407	TRIM28	3	11	14	200.688
#408	PLAG1	3	8	11	1342.499
#409	HEYL	3	8	11	892.016
#410	ZNF189	3	13	16	206.677
#411	ZNF396	3	10	13	655.233
#412	JDP2	3	10	13	637.689
#413	ZNF33B	3	9	12	295.301
#414	RXRB	3	11	14	2819.189
#415	TWIST1	3	15	18	687.229
#416	ETV6	3	12	15	304.163
#417	NR3C1	2	15	17	1969.934
#418	ZSCAN2	2	9	11	162.772
#419	CREM	2	17	19	2433.901
#420	ATF1	2	7	9	735.255
#421	LEF1	2	11	13	8313.631
#422	ATF4	2	11	13	2267.807
#423	SP4	2	13	15	1932.826
#424	MXD1	2	11	13	416.156
#425	AEBP1	2	10	12	335.138
#426	SLC26A3	2	13	15	3839.106
#427	ZNF174	2	13	15	7250.826
#428	HOXB2	2	13	15	4932.443
#429	HOXB3	2	12	14	517.792
#430	NR2C1	2	13	15	1172.219
#431	HOXA5	2	15	17	901.103
#432	SNAI2	2	13	15	3686.68
#433	FOXO1	2	13	15	2313.464
#434	RHOXF1	2	11	13	159.273
#435	ZEB1	2	11	13	125.793
#436	TEAD1	2	7	9	794.193
#437	RFXAP	2	16	18	486.729
#438	PEG3	2	17	19	245.62
#439	HMBOX1	2	10	12	685.922
#440	OTX2	2	9	11	1954.052
#441	TAF4	2	13	15	508.357
#442	MESP1	2	10	12	411.028
#443	ZSCAN5A	2	8	10	145.773
#444	RORB	2	7	9	592.65
#445	CITED1	2	10	12	261.801
#446	KLF7	2	8	10	180.806
#447	ATF3	2	7	9	216.466
#448	ERG	2	13	15	963.874
#449	ZNF133	2	13	15	99.3
#450	RORC	2	8	10	761.463
#451	ESRRG	2	16	18	711.376
#452	CTNNB1	2	11	13	984.527
#453	FOXQ1	2	9	11	4731.34
#454	NFATC1	2	15	17	2516.273
#455	NR3C2	2	13	15	1397.192
#456	HOXA10	1	10	11	228.565
#457	SREBF2	1	15	16	1415.18
#458	ZHX3	1	13	14	864.18
#459	LZTS1	1	5	6	519.275
#460	FOXP2	1	9	10	72.226
#461	IRX4	1	10	11	68.497
#462	SOLH	1	8	9	26.472
#463	HMGA2	1	12	13	1053.443
#464	MAF	1	14	15	637.174
#465	ANKRD30A	1	10	11	40.88
#466	HOXC4	1	12	13	1438.84
#467	REST	1	4	5	6.609
#468	RUNX1T1	1	15	16	89.038
#469	MYNN	1	8	9	2163.741
#470	SATB1	1	13	14	2869.866
#471	SIX1	1	11	12	166.912
#472	TSC22D1	1	13	14	61.181
#473	KLF9	1	10	11	60.908
#474	HEY1	1	14	15	311.79
#475	TBX5	1	12	13	3076.985
#476	TSC22D2	1	10	11	2047.036
#477	SOX9	1	13	14	6065.896
#478	LHX6	1	5	6	36.754
#479	TSHZ2	1	9	10	1780.872
#480	RORA	1	14	15	640.076
#481	SLC30A9	1	13	14	607.19
#482	MAFB	1	15	16	32.453
#483	CREBL2	1	14	15	11270.788
#484	RARB	1	13	14	88.627
#485	GATAD2B	1	7	8	6.764
#486	KLF2	1	13	14	630.919
#487	ZFP90	1	14	15	1154.264
#488	MYC	0	17	17	0
#489	NR2E3	0	8	8	0
#490	CITED2	0	12	12	0
#491	SMAD9	0	17	17	0
#492	ETV1	0	5	5	0
#493	ZNF397	0	9	9	0
#494	GATA2	0	10	10	0
#495	IRF4	0	4	4	0
#496	WNT5A	0	14	14	0
#497	ZNF93	0	11	11	0
#498	HOXA3	0	6	6	0
#499	TFEB	0	15	15	0
#500	SCML2	0	12	12	0